BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0010.17
         (237 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

SFRF_HUMAN (O95104) Splicing factor, arginine/serine-rich 15 (CT...    41  0.003
RU17_ARATH (Q42404) U1 small nuclear ribonucleoprotein 70 kDa (U...    39  0.008
TF20_MOUSE (Q9EPQ8) Transcription factor 20 (Stromelysin 1 PDGF-...    39  0.014
GATB_BOMMO (P52167) Transcription factor BCFI (GATA-beta) (BmGAT...    39  0.014
RU17_MOUSE (Q62376) U1 small nuclear ribonucleoprotein 70 kDa (U...    37  0.031
TF20_HUMAN (Q9UGU0) Transcription factor 20 (Stromelysin 1 PDGF-...    36  0.070
RU17_HUMAN (P08621) U1 small nuclear ribonucleoprotein 70 kDa (U...    36  0.092
Y220_HUMAN (Q92617) Hypothetical protein KIAA0220 (Fragment)           35  0.12
PPIG_RAT (O55035) Peptidyl-prolyl cis-trans isomerase G (EC 5.2....    35  0.16
ACIN_MOUSE (Q9JIX8) Apoptotic chromatin condensation inducer in ...    35  0.16
RP3A_MOUSE (P47708) Rabphilin-3A (Exophilin 1)                         34  0.27
FURI_BOVIN (Q28193) Furin precursor (EC 3.4.21.75) (Paired basic...    34  0.27
SOX9_PONPY (P61754) Transcription factor SOX-9                         34  0.35
SOX9_PIG (O18896) Transcription factor SOX-9                           34  0.35
SOX9_PANTR (Q9BG89) Transcription factor SOX-9                         34  0.35
SOX9_MACMU (P61753) Transcription factor SOX-9                         34  0.35
SOX9_HUMAN (P48436) Transcription factor SOX-9                         34  0.35
IF3A_MOUSE (P23116) Eukaryotic translation initiation factor 3 s...    33  0.45
DED2_HUMAN (Q8WXF8) DNA-binding death effector domain-containing...    33  0.45
V70K_TYMVC (P28478) 69 kDa protein                                     33  0.59

>SFRF_HUMAN (O95104) Splicing factor, arginine/serine-rich 15
            (CTD-binding SR-like protein RA4) (Fragment)
          Length = 1157

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 32/111 (28%), Positives = 46/111 (40%), Gaps = 24/111 (21%)

Query: 112  PATQQPYNLHEHRQQQQPPPPQPTTFTLSTEPRKTDKRRR-----------RRDPGKEIE 160
            P  Q P    + +QQQ PP  QP       +  + D R++           RR  G  +E
Sbjct: 961  PQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVE 1020

Query: 161  RDREPPIETSHPNLHRDRDGGGMERR--GARS------RETAKRDRETMDH 203
             DRE      + N + DRD    +RR  G RS      R+  +R+R +  H
Sbjct: 1021 NDRE-----RYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGH 1066



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 34/134 (25%), Positives = 49/134 (36%), Gaps = 13/134 (9%)

Query: 94  GFLVDPKFT-VASPIFTLNPATQQPYNLHEHRQQQQPPPPQPTTFTLSTEP--------- 143
           G L  P F  +A P+    P  QQP+     + Q +P   +P    +  E          
Sbjct: 379 GLLPTPPFPPMAQPVIPPTPPVQQPFQA-SFQAQNEPLTQKPHQQEMEVEQPCIQEVKRH 437

Query: 144 RKTDKRRRRRDPGKEIERDREPPIETSHPNLHRDRDGGGMERR--GARSRETAKRDRETM 201
              +++ R R   +  +R R      S  + HR       +RR    RSR   +RDRE  
Sbjct: 438 MSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKE 497

Query: 202 DHHHALHLPPQIPE 215
                  LP   PE
Sbjct: 498 RERRQKGLPQVKPE 511


>RU17_ARATH (Q42404) U1 small nuclear ribonucleoprotein 70 kDa (U1
           snRNP 70 kDa) (snRNP70) (U1-70K)
          Length = 427

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 30/84 (35%), Positives = 36/84 (42%), Gaps = 16/84 (19%)

Query: 132 PQPTTFTLSTEPRKTDKRRRRRDPGKEIERDRE------------PPIETSHPNLHRDRD 179
           PQ  T       R  ++R + R+ GKE ER RE             P E  H   HRDRD
Sbjct: 248 PQGRTSQSEEPSRPREEREKSREKGKERERSRELSHEQPRERSRDRPREDKH---HRDRD 304

Query: 180 GGGMER-RGARSRETAKRDRETMD 202
            GG +R R +R      RDR   D
Sbjct: 305 QGGRDRDRDSRRDRDRTRDRGDRD 328


>TF20_MOUSE (Q9EPQ8) Transcription factor 20 (Stromelysin 1
            PDGF-responsive element-binding protein) (SPRE-binding
            protein) (Nuclear factor SPBP)
          Length = 1983

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 22/65 (33%), Positives = 31/65 (46%), Gaps = 9/65 (13%)

Query: 119  NLHEHRQQQQPPPPQPTTFTLST-----EPRKTDKRRRRRDPG----KEIERDREPPIET 169
            N  + +QQQ PPPPQP      +     +P+K  +RR RR PG    K   +   P +E 
Sbjct: 1576 NKQKKQQQQPPPPPQPPQMPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEP 1635

Query: 170  SHPNL 174
              P +
Sbjct: 1636 QEPEI 1640


>GATB_BOMMO (P52167) Transcription factor BCFI (GATA-beta)
           (BmGATA-beta)
          Length = 508

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 44/128 (34%), Positives = 51/128 (39%), Gaps = 14/128 (10%)

Query: 116 QPYNLHEHRQQQQPPPP---QPTTFTLSTEPRKTDKRRRRR--DPGKEIERDREPPIETS 170
           QPY+ H      +PP P    PT  T +  P    +RR RR   P      D  PP   S
Sbjct: 47  QPYS-HLDDSLFKPPTPGSAPPTASTCAGVPSSAPRRRPRRLRPPAPLHYDDYAPPPPYS 105

Query: 171 HPNLHRDRDGGGMERRGARSRETAKRDRETMDHHHALHLPPQIPEPTFALGFLRLVVVL- 229
           H + H    GGG    GA SR TA R          LH   +   P  AL  +R V  L 
Sbjct: 106 HDHHHHLEQGGG--GNGAASRCTAVR---LQQRRAILHQRSRPLRPAAALDRVRRVSELR 160

Query: 230 --GDGGGR 235
              D GGR
Sbjct: 161 QQRDTGGR 168


>RU17_MOUSE (Q62376) U1 small nuclear ribonucleoprotein 70 kDa (U1
           SNRNP 70 kDa) (snRNP70) (Fragment)
          Length = 378

 Score = 37.4 bits (85), Expect = 0.031
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 12/82 (14%)

Query: 130 PPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIETSHPNLHRDRD---------- 179
           P P P         R+ ++R R R+  KE ER R    +    +  RD+D          
Sbjct: 153 PGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRQRRSRSRDKDERRRSRERTK 212

Query: 180 --GGGMERRGARSRETAKRDRE 199
                 +RR +RSRE A+R+RE
Sbjct: 213 DKDRDRKRRSSRSRERARRERE 234



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 1/79 (1%)

Query: 121 HEHRQQQQPPPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIETSHPNLHRDRDG 180
           H  R        +P    L    R  D+ R RR+  +E +++RE     S     R R  
Sbjct: 140 HSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRQRRSRSR 199

Query: 181 GGMERRGARSRETAKRDRE 199
              ERR +R R T  +DR+
Sbjct: 200 DKDERRRSRER-TKDKDRD 217


>TF20_HUMAN (Q9UGU0) Transcription factor 20 (Stromelysin 1
            PDGF-responsive element-binding protein) (SPRE-binding
            protein) (Nuclear factor SPBP) (AR1)
          Length = 1960

 Score = 36.2 bits (82), Expect = 0.070
 Identities = 20/67 (29%), Positives = 33/67 (48%), Gaps = 11/67 (16%)

Query: 119  NLHEHRQQQQPPPPQPTTFTL-------STEPRKTDKRRRRRDPG----KEIERDREPPI 167
            ++++ ++QQQPPPP P    +         +P+K  +RR RR PG    K   +   P +
Sbjct: 1546 SVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIV 1605

Query: 168  ETSHPNL 174
            E   P +
Sbjct: 1606 EPQEPEI 1612


>RU17_HUMAN (P08621) U1 small nuclear ribonucleoprotein 70 kDa (U1
           snRNP 70 kDa) (snRNP70) (U1-70K)
          Length = 437

 Score = 35.8 bits (81), Expect = 0.092
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 18/85 (21%)

Query: 130 PPPQPTTFTLSTEPRKTDKRRRRRDPGKEIER---------------DREPPIETSHPNL 174
           P P P         R+ ++R R R+  KE ER               D+E    +   + 
Sbjct: 223 PGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSK 282

Query: 175 HRDRDGGGMERRGARSRETAKRDRE 199
            +DRD    +RR +RSRE A+R+RE
Sbjct: 283 DKDRD---RKRRSSRSRERARRERE 304



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 1/80 (1%)

Query: 121 HEHRQQQQPPPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIETSHPNLHRDRDG 180
           H  R        +P    L    R  D+ R RR+  +E +++RE     S     R R  
Sbjct: 210 HSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSR 269

Query: 181 GGMERRGARSRETAK-RDRE 199
              ERR +R R   K RDR+
Sbjct: 270 DKEERRRSRERSKDKDRDRK 289


>Y220_HUMAN (Q92617) Hypothetical protein KIAA0220 (Fragment)
          Length = 884

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 31/129 (24%), Positives = 45/129 (34%), Gaps = 31/129 (24%)

Query: 106 PIFTLNPATQQPYNLHEHRQQQQPPPPQPTTFTL-STEPRKTDKRRRRRD---------- 154
           P+ T     ++P      R  +  PPP+P    +   EP +  KRRR  D          
Sbjct: 763 PLATQEAEAEKPRKPKRQRAAEMEPPPEPKRRRVGDVEPSRKPKRRRAADVEPSSPEPKR 822

Query: 155 -------PGKEIERDREPPIETSHPNLHRDRDGGGMERRGARSRETAKRDRETMDHHHAL 207
                  P ++ +R R   +E S P   R R G     R  + R  A             
Sbjct: 823 RRVGDVEPSRKPKRRRAADVEPSSPEPKRRRVGDVEPSRKPKRRRAA------------- 869

Query: 208 HLPPQIPEP 216
            + P +PEP
Sbjct: 870 DVEPSLPEP 878


>PPIG_RAT (O55035) Peptidyl-prolyl cis-trans isomerase G (EC
           5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G)
           (Rotamase G) (Cyclophilin G) (Matrin cyclophilin)
           (Matrin-cyp)
          Length = 752

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 10/93 (10%)

Query: 124 RQQQQPPPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIETSHPNLHR-----DR 178
           R ++ PP P+       + P+  DK R+ R+  +E ER+  PP   S P  ++      R
Sbjct: 271 RPEEIPPIPENRFLMRKSPPKADDKERKNRE--RERERECNPP--NSQPASYQRRFLVTR 326

Query: 179 DGGGMERRGARSRETAKRDRETMDHHHALHLPP 211
            G  ++ RG R   T  R R + D       PP
Sbjct: 327 SGRKIKGRGPRRYRTPSRSR-SRDRFRRSETPP 358


>ACIN_MOUSE (Q9JIX8) Apoptotic chromatin condensation inducer in the
            nucleus (Acinus)
          Length = 1338

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 35/135 (25%), Positives = 53/135 (38%), Gaps = 26/135 (19%)

Query: 85   REKQKQQRQGFLVDPKF--TVASPIFTLNPATQQPYNLHEHRQQQQPPPPQPTTFTLSTE 142
            +EK +++    L+D  F  T A+P     P T+      E  Q ++    +        E
Sbjct: 1198 KEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTESQIVQKEAEQAERAKEREKRRKEREEE 1257

Query: 143  PRKTDK------------RRRRRDPGKEIERDREPPIETSHPNLHRDRDGGGMERRGARS 190
             +K  +            R +RR+  +E ERDRE           R+RD G  ER   R 
Sbjct: 1258 EQKEREKEAERERNRQLEREKRREHSRERERDRE-----------RERDRGDRERERERD 1306

Query: 191  RETAK-RDRETMDHH 204
            R+  + RDR     H
Sbjct: 1307 RDRGRERDRRDTKRH 1321


>RP3A_MOUSE (P47708) Rabphilin-3A (Exophilin 1)
          Length = 681

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 24/79 (30%), Positives = 29/79 (36%), Gaps = 4/79 (5%)

Query: 131 PPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIETSHPNL----HRDRDGGGMERR 186
           P QP     + E    + R   R P +    DR PP +   P+L     R   G    R 
Sbjct: 174 PQQPAGEPATQEQPTPESRHPARAPARGDMEDRRPPGQKPGPDLTSAPGRGSHGPPTRRA 233

Query: 187 GARSRETAKRDRETMDHHH 205
                 TA RD E  DH H
Sbjct: 234 SEARMSTAARDSEGWDHAH 252


>FURI_BOVIN (Q28193) Furin precursor (EC 3.4.21.75) (Paired basic
           amino acid residue cleaving enzyme) (PACE) (Dibasic
           processing enzyme) (Trans Golgi network protease furin)
          Length = 797

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 14/31 (45%), Positives = 20/31 (64%)

Query: 114 TQQPYNLHEHRQQQQPPPPQPTTFTLSTEPR 144
           ++Q  +  E  QQQ PPPP+P    ++TEPR
Sbjct: 676 SRQSQSSRESHQQQPPPPPRPPPAEVATEPR 706


>SOX9_PONPY (P61754) Transcription factor SOX-9
          Length = 509

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 3/47 (6%)

Query: 122 EHRQQQQPPPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIE 168
           EH  Q Q PP  PTT     +P K D +R  R      E  R+PPI+
Sbjct: 226 EHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLP---EGGRQPPID 269


>SOX9_PIG (O18896) Transcription factor SOX-9
          Length = 509

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 3/47 (6%)

Query: 122 EHRQQQQPPPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIE 168
           EH  Q Q PP  PTT     +P K D +R  R      E  R+PPI+
Sbjct: 226 EHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLP---EGGRQPPID 269


>SOX9_PANTR (Q9BG89) Transcription factor SOX-9
          Length = 509

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 3/47 (6%)

Query: 122 EHRQQQQPPPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIE 168
           EH  Q Q PP  PTT     +P K D +R  R      E  R+PPI+
Sbjct: 226 EHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLP---EGGRQPPID 269


>SOX9_MACMU (P61753) Transcription factor SOX-9
          Length = 509

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 3/47 (6%)

Query: 122 EHRQQQQPPPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIE 168
           EH  Q Q PP  PTT     +P K D +R  R      E  R+PPI+
Sbjct: 226 EHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLP---EGGRQPPID 269


>SOX9_HUMAN (P48436) Transcription factor SOX-9
          Length = 509

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 3/47 (6%)

Query: 122 EHRQQQQPPPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIE 168
           EH  Q Q PP  PTT     +P K D +R  R      E  R+PPI+
Sbjct: 226 EHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLP---EGGRQPPID 269


>IF3A_MOUSE (P23116) Eukaryotic translation initiation factor 3
            subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3
            p185) (eIF3a) (p162 protein) (Centrosomin)
          Length = 1344

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 11/85 (12%)

Query: 119  NLHEHRQQQQPPPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIETSHPNLHRDR 178
            +L + R ++ PP        L +E  +    RR  D   +   +R+PP     P L RDR
Sbjct: 1252 DLRDDRDRRGPP--------LRSEREEASSWRRTDDRKDDRTEERDPPRRVPPPALSRDR 1303

Query: 179  DGGGMERRGARSRET--AKRDRETM 201
            +    ER G + + +  A++DRE++
Sbjct: 1304 E-REREREGEKEKASWRAEKDRESL 1327


>DED2_HUMAN (Q8WXF8) DNA-binding death effector domain-containing
           protein 2 (DED-containing protein FLAME-3)
          Length = 326

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 19/71 (26%), Positives = 32/71 (44%)

Query: 121 HEHRQQQQPPPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIETSHPNLHRDRDG 180
           H  R++++P  P+  ++  S+  ++T+   RRR         ++   ET  P   R R  
Sbjct: 101 HLARKRRRPVSPERYSYGTSSSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRS 160

Query: 181 GGMERRGARSR 191
            G    GAR R
Sbjct: 161 RGRPSGGARRR 171


>V70K_TYMVC (P28478) 69 kDa protein
          Length = 628

 Score = 33.1 bits (74), Expect = 0.59
 Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 7/108 (6%)

Query: 117 PYNLHEHRQQQQPPPPQPTTFTLSTEPRKTDKRRRRRDPGKEIERDREPPIETSHPNLHR 176
           P++ H  R    P  P        T+PR + ++ R    G        P +     ++H 
Sbjct: 139 PHHFHARRPDVLPSVPDHGPVLAETKPRTSVRQPRSATRGPSFRPILLPKVV----HVHD 194

Query: 177 DRDGGGMERRGARSRE---TAKRDRETMDHHHALHLPPQIPEPTFALG 221
           D     +  RG+RSR+   T +R     +  H+   PP + +    LG
Sbjct: 195 DPPHSSLRPRGSRSRQLQPTVRRPLLAPNQFHSPRQPPPLSDDPGILG 242


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.318    0.138    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,683,118
Number of Sequences: 164201
Number of extensions: 1512994
Number of successful extensions: 6020
Number of sequences better than 10.0: 104
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 5728
Number of HSP's gapped (non-prelim): 244
length of query: 237
length of database: 59,974,054
effective HSP length: 107
effective length of query: 130
effective length of database: 42,404,547
effective search space: 5512591110
effective search space used: 5512591110
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)