BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0004a.6
         (418 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

PCY2_HUMAN (Q99447) Ethanolamine-phosphate cytidylyltransferase ...   330  5e-90
PCY2_RAT (O88637) Ethanolamine-phosphate cytidylyltransferase (E...   323  5e-88
PCY2_MOUSE (Q922E4) Ethanolamine-phosphate cytidylyltransferase ...   319  9e-87
ECT1_SCHPO (Q9UTI6) Probable ethanolamine-phosphate cytidylyltra...   170  5e-42
ECT1_YEAST (P33412) Ethanolamine-phosphate cytidylyltransferase ...   148  3e-35
CTPT_PLAFK (P49587) Choline-phosphate cytidylyltransferase (EC 2...   110  9e-24
CTPU_RAT (Q9QZC4) Choline-phosphate cytidylyltransferase B (EC 2...   108  2e-23
CTPU_HUMAN (Q9Y5K3) Choline-phosphate cytidylyltransferase B (EC...   108  2e-23
CTPT_YEAST (P13259) Choline-phosphate cytidylyltransferase (EC 2...   107  7e-23
CTPT_RAT (P19836) Choline-phosphate cytidylyltransferase A (EC 2...   105  2e-22
CTPT_HUMAN (P49585) Choline-phosphate cytidylyltransferase A (EC...   105  2e-22
CTPT_MOUSE (P49586) Choline-phosphate cytidylyltransferase A (EC...   105  3e-22
CTPT_CRIGR (P49584) Choline-phosphate cytidylyltransferase A (EC...   103  8e-22
CTPT_CAEEL (P49583) Putative choline-phosphate cytidylyltransfer...    99  2e-20
HLDE_HAEDU (Q7VM30) Bifunctional protein hldE [Includes: D-beta-...    69  2e-11
HLDE_VIBVY (Q7MNY3) Bifunctional protein hldE [Includes: D-beta-...    69  2e-11
HLDE_VIBVU (Q8DEH7) Bifunctional protein hldE [Includes: D-beta-...    69  2e-11
HLDE_SHEON (Q8EAZ2) Bifunctional protein hldE [Includes: D-beta-...    67  7e-11
HLDE_HELHP (Q7VFZ3) Bifunctional protein hldE [Includes: D-beta-...    67  1e-10
HLDE_VIBPA (Q87SJ9) Bifunctional protein hldE [Includes: D-beta-...    66  1e-10

>PCY2_HUMAN (Q99447) Ethanolamine-phosphate cytidylyltransferase (EC
           2.7.7.14) (Phosphorylethanolamine transferase)
           (CTP:phosphoethanolamine cytidylyltransferase)
          Length = 389

 Score =  330 bits (845), Expect = 5e-90
 Identities = 159/359 (44%), Positives = 236/359 (65%), Gaps = 14/359 (3%)

Query: 61  GKRRVRVYMDGCFDLMHYGHANALRQAKALGDELVVGLVNDEEILATKGPPVLTMAERLA 120
           G+R VRV+ DGC+D++HYGH+N LRQA+A+GD L+VG+  DEEI   KGPPV T  ER  
Sbjct: 19  GRRAVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDEEIAKHKGPPVFTQEERYK 78

Query: 121 LVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAKKAGR 180
           +V  +KWVDEV+  APY  T + L +    Y  D+ +HG+D  L  DG D Y   K+AGR
Sbjct: 79  MVQAIKWVDEVVPAAPYVTTLETLDK----YNCDFCVHGNDITLTVDGRDTYEEVKQAGR 134

Query: 181 YKQIKRTEGVSSTDIVGRIMSSLKDQKTCEDQNGTDVKRQEESMSKD-------SHISQF 233
           Y++ KRT+GVS+TD+VGR++   K   + ++ + ++ +   +S  K        + +SQF
Sbjct: 135 YRECKRTQGVSTTDLVGRMLLVTKAHHSSQEMS-SEYREYADSFGKCPGGRNPWTGVSQF 193

Query: 234 LPTSRRIVQFSNGKGPGPNARIVYIDGAFDLFHAGHVEILKRARELGD--FLLVGIHSDE 291
           L TS++I+QF++GK P P   ++Y+ GAFDLFH GHV+ L++   L +  +++ G+H D+
Sbjct: 194 LQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLEKVHRLAERPYIIAGLHFDQ 253

Query: 292 TVSEHRGNHYPIMHLHERSLSVLACRHVDEVIIGAPWEITKDMITTFNISLVVHGTVAEK 351
            V+ ++G +YPIM+LHER+LSVLACR+V EV+IGAP+ +T ++++ F + LV HG     
Sbjct: 254 EVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYAVTAELLSHFKVDLVCHGKTEII 313

Query: 352 SLHSERDPYEVPKSMGMFRLLESPKDITTTTVAQRILANHEAYEKRNAKKSQSEKRYYE 410
                 DPY+ PK  G+FR ++S  ++TT  + QRI+ N   YE RN KK   E  + E
Sbjct: 314 PDRDGSDPYQEPKRRGIFRQIDSGSNLTTDLIVQRIITNRLEYEARNQKKEAKELAFLE 372


>PCY2_RAT (O88637) Ethanolamine-phosphate cytidylyltransferase (EC
           2.7.7.14) (Phosphorylethanolamine transferase)
           (CTP:phosphoethanolamine cytidylyltransferase)
          Length = 404

 Score =  323 bits (828), Expect = 5e-88
 Identities = 161/381 (42%), Positives = 234/381 (61%), Gaps = 32/381 (8%)

Query: 57  KKKSGKRRVRVYMDGCFDLMHYGHANALRQAKALGDELVVGLVNDEEILATKGPPVLTMA 116
           K   G+R VRV+ DGC+D++HYGH+N LRQA+A+GD L+VG+  DEEI   KGPPV T  
Sbjct: 15  KGPGGQRTVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDEEIAKHKGPPVFTQE 74

Query: 117 ERLALVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAK 176
           ER  +V  +KWVDEV+  APY  T + L +    +  D+ +HG+D  L  DG D Y   K
Sbjct: 75  ERYKMVQAIKWVDEVVPAAPYVTTLETLDK----HNCDFCVHGNDITLTVDGRDTYEEVK 130

Query: 177 KAGRYKQIKRTEGVSSTDIVGRIMSSLKDQKTCEDQNGTDVKRQEESMSKDSH------- 229
           +AGRY++ KRT+GVS+TD+VGR++   K   + ++ + ++ +   +S  K  H       
Sbjct: 131 QAGRYRECKRTQGVSTTDLVGRMLLVTKAHHSSQEMS-SEYREYADSFGKPPHPTPAGDT 189

Query: 230 ------------------ISQFLPTSRRIVQFSNGKGPGPNARIVYIDGAFDLFHAGHVE 271
                             +SQFL TS++I+QF++GK P P   ++Y+ GAFDLFH GHV+
Sbjct: 190 LSSEVSSQCPGGQSPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVD 249

Query: 272 ILKRARELGD--FLLVGIHSDETVSEHRGNHYPIMHLHERSLSVLACRHVDEVIIGAPWE 329
            L+   +L    +++ G+H D+ V+ ++G +YPIM+LHER+LSVLACR+V EV+IGAP+ 
Sbjct: 250 FLQEVHKLAKRPYVIAGLHFDQEVNRYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYS 309

Query: 330 ITKDMITTFNISLVVHGTVAEKSLHSERDPYEVPKSMGMFRLLESPKDITTTTVAQRILA 389
           +T +++  F + LV HG           DPYE PK  G+F  ++S  D+TT  + QRI+ 
Sbjct: 310 VTAELLNHFKVDLVCHGKTEIVPDRDGSDPYEEPKRRGIFCQIDSGSDLTTDLIVQRIIK 369

Query: 390 NHEAYEKRNAKKSQSEKRYYE 410
           N   YE RN KK   E  + E
Sbjct: 370 NRLEYEARNQKKEAKELAFLE 390


>PCY2_MOUSE (Q922E4) Ethanolamine-phosphate cytidylyltransferase (EC
           2.7.7.14) (Phosphorylethanolamine transferase)
           (CTP:phosphoethanolamine cytidylyltransferase)
          Length = 404

 Score =  319 bits (817), Expect = 9e-87
 Identities = 159/381 (41%), Positives = 233/381 (60%), Gaps = 32/381 (8%)

Query: 57  KKKSGKRRVRVYMDGCFDLMHYGHANALRQAKALGDELVVGLVNDEEILATKGPPVLTMA 116
           K    +R VRV+ DGC+D++HYGH+N LRQA+A+GD L+VG+  DEEI   KGPPV T  
Sbjct: 15  KGPGDQRIVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDEEIAKHKGPPVFTQE 74

Query: 117 ERLALVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAK 176
           ER  +V  +KWVDEV+  APY  T + L +    +  D+ +HG+D  L  DG D Y   K
Sbjct: 75  ERYKMVQAIKWVDEVVPAAPYVTTLETLDK----HNCDFCVHGNDITLTVDGRDTYEEVK 130

Query: 177 KAGRYKQIKRTEGVSSTDIVGRIMSSLKDQKTCEDQNGTDVKRQEESMSKDSH------- 229
           +AGRY++ KRT+GVS+TD+VGR++   K   + ++ + ++ +   +S  K  H       
Sbjct: 131 QAGRYRECKRTQGVSTTDLVGRMLLVTKAHHSSQEMS-SEYREYADSFGKPPHPTPAGDT 189

Query: 230 ------------------ISQFLPTSRRIVQFSNGKGPGPNARIVYIDGAFDLFHAGHVE 271
                             +SQFL TS++I+QF++GK P P   ++Y+ GAFDLFH GHV+
Sbjct: 190 LSSEVSSQCPGGQSPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVD 249

Query: 272 ILKRARELGD--FLLVGIHSDETVSEHRGNHYPIMHLHERSLSVLACRHVDEVIIGAPWE 329
            L+   +L    +++ G+H D+ V+ ++G +YPIM+LHER+LSVLACR+V EV+IGAP+ 
Sbjct: 250 FLQEVHKLAKRPYVIAGLHFDQEVNRYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYS 309

Query: 330 ITKDMITTFNISLVVHGTVAEKSLHSERDPYEVPKSMGMFRLLESPKDITTTTVAQRILA 389
           +T +++  F + LV HG           DPY+ PK  G+F  ++S  D+TT  + QRI+ 
Sbjct: 310 VTAELLNHFKVDLVCHGKTEIVPDRDGSDPYQEPKRRGIFYQIDSGSDLTTDLIVQRIIK 369

Query: 390 NHEAYEKRNAKKSQSEKRYYE 410
           N   YE RN KK   E  + E
Sbjct: 370 NRLEYEARNQKKEAKELAFLE 390


>ECT1_SCHPO (Q9UTI6) Probable ethanolamine-phosphate
           cytidylyltransferase (EC 2.7.7.14)
           (Phosphorylethanolamine transferase)
           (CTP:phosphoethanolamine cytidylyltransferase)
          Length = 365

 Score =  170 bits (431), Expect = 5e-42
 Identities = 95/273 (34%), Positives = 150/273 (54%), Gaps = 20/273 (7%)

Query: 66  RVYMDGCFDLMHYGHANALRQAKALGDELVVGLVNDEEILATKGPPVLTMAERLALVSGL 125
           R+++DGC D  HYGH+NA+ QAK LG+ LV+G+ +DEEI   KGPPV+T+ ER    +  
Sbjct: 10  RLWLDGCMDFFHYGHSNAILQAKQLGETLVIGIHSDEEITLNKGPPVMTLEERCLSANTC 69

Query: 126 KWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAKKAGRYKQIK 185
           KWVDEV+  APY    +++ R    Y   YV+HGDD     +G D Y  AK A +Y ++K
Sbjct: 70  KWVDEVVPSAPYVFDLEWMRR----YGCQYVVHGDDISTDANGDDCYRFAKAADQYLEVK 125

Query: 186 RTEGVSSTDIVGRIMSS--LKDQKTCEDQNGTDVKRQEESMSKDSHISQFLPT------- 236
           RTEGVS+T+++ R++SS  L+   T      + +       +    ++ F          
Sbjct: 126 RTEGVSTTELLDRLLSSVPLEIYSTPVSVLSSQIDLLRRFATDSDGLTPFTDVFIYNTEK 185

Query: 237 SRRIVQFSNGKGPGPNARIVYIDGAFDLFHAGHVEILKRAREL--GDFLLVGIHSDETVS 294
              ++  +      P   I+YIDG +DLF   H+  L+    +  G  ++ GI +DE   
Sbjct: 186 PETLISGTTLLRLNPEKNIIYIDGDWDLFTEKHISALELCTRMFPGIPIMAGIFADEKCF 245

Query: 295 EHRGNHYPIMHLHERSLSVLACRHVDEVIIGAP 327
           E      P+++L ER L++L C+++  +++G P
Sbjct: 246 EK-----PMLNLLERILNLLQCKYISSILVGPP 273



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 43/135 (31%), Positives = 77/135 (56%), Gaps = 3/135 (2%)

Query: 256 VYIDGAFDLFHAGHVEILKRARELGDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSVLA 315
           +++DG  D FH GH   + +A++LG+ L++GIHSDE ++ ++G   P+M L ER LS   
Sbjct: 11  LWLDGCMDFFHYGHSNAILQAKQLGETLVIGIHSDEEITLNKGP--PVMTLEERCLSANT 68

Query: 316 CRHVDEVIIGAPWEITKDMITTFNISLVVHGTVAEKSLHSERDPYEVPKSMGMFRLLESP 375
           C+ VDEV+  AP+    + +  +    VVHG       + + D Y   K+   +  ++  
Sbjct: 69  CKWVDEVVPSAPYVFDLEWMRRYGCQYVVHGDDISTDANGD-DCYRFAKAADQYLEVKRT 127

Query: 376 KDITTTTVAQRILAN 390
           + ++TT +  R+L++
Sbjct: 128 EGVSTTELLDRLLSS 142



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 25/102 (24%), Positives = 47/102 (45%), Gaps = 10/102 (9%)

Query: 67  VYMDGCFDLMHYGHANALRQAKAL--GDELVVGLVNDEEILATKGPPVLTMAERLALVSG 124
           +Y+DG +DL    H +AL     +  G  ++ G+  DE+       P+L + ER+  +  
Sbjct: 205 IYIDGDWDLFTEKHISALELCTRMFPGIPIMAGIFADEKCFE---KPMLNLLERILNLLQ 261

Query: 125 LKWVDEVITDAPYA---ITEQFLHRLFHEY--KIDYVIHGDD 161
            K++  ++   P A    + +++   F E   K+ Y I   D
Sbjct: 262 CKYISSILVGPPPASLFASSKYIKLCFDEQISKVYYPIFSTD 303


>ECT1_YEAST (P33412) Ethanolamine-phosphate cytidylyltransferase (EC
           2.7.7.14) (Phosphorylethanolamine transferase)
           (CTP:phosphoethanolamine cytidylyltransferase)
          Length = 323

 Score =  148 bits (373), Expect = 3e-35
 Identities = 110/348 (31%), Positives = 170/348 (48%), Gaps = 43/348 (12%)

Query: 66  RVYMDGCFDLMHYGHANALRQAKAL----GDELVVGLVNDEEILATKGPPVLTMAERLAL 121
           +V++DGCFD  H+GHA A+ QA+        +L  G+  DE+I   KG PV+  +ER   
Sbjct: 9   KVWIDGCFDFTHHGHAGAILQARRTVSKENGKLFCGVHTDEDIQHNKGTPVMNSSERYEH 68

Query: 122 VSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAKKAGRY 181
               +W  EV+  APY     ++ +    Y+  YV+HGDD  +  +G D Y   K+ GR+
Sbjct: 69  TRSNRWCSEVVEAAPYVTDPNWMDK----YQCQYVVHGDDITIDANGEDCYKLVKEMGRF 124

Query: 182 KQIKRTEGVSSTDIVGRIMSSLKDQKTCEDQNGTDVKRQEESMSKDSHISQFLPTSRRIV 241
           K +KRT GVS+T+I+ RI++      T  D   T  +    S+++D+ +S+     +R +
Sbjct: 125 KVVKRTYGVSTTEIIHRILTKKSLPPTHPDYYPTTQELSFYSVAQDA-VSKHCYVFQRDL 183

Query: 242 Q--FSNGKGPGPNARIVYIDGAFDLFHAGHVEILKRAR---ELGDFLLVGIHSDETVSEH 296
                NG         VY+DG FDLFH G ++ L++ +        L+VGI    T S++
Sbjct: 184 DNVLVNGGYKFDAEDCVYVDGDFDLFHMGDIDQLRKLKMDLHPDKKLIVGI----TTSDY 239

Query: 297 RGNHYPIMHLHERSLSVLACRHVDEVIIGAPWEITKDMITTFNISLVVHGTVAEKSLHSE 356
                 IM + ER LSVL+C++VD VII A        ++ +N      GT         
Sbjct: 240 SST---IMTMKERVLSVLSCKYVDAVIIDA----DATSMSQYNCEKYHIGTA-------- 284

Query: 357 RDPYEVPKSMGMFRLLESPKDITTTTVAQRILANHEAYEKRNAKKSQS 404
                V  + G F      + +T   + +R+ +  E Y  RN KK  S
Sbjct: 285 -----VLTAAGKF-----SEYLTKELIVKRVESQREVYIARNQKKGMS 322


>CTPT_PLAFK (P49587) Choline-phosphate cytidylyltransferase (EC
           2.7.7.15) (Phosphorylcholine transferase)
           (CTP:phosphocholine cytidylyltransferase) (CT) (CCT)
          Length = 370

 Score =  110 bits (274), Expect = 9e-24
 Identities = 60/163 (36%), Positives = 90/163 (54%), Gaps = 24/163 (14%)

Query: 63  RRVRVYMDGCFDLMHYGHANALRQAKALGDE--LVVGLVNDEEILATKGPPVLTMAERLA 120
           + V +Y DG +D++H GH   L QAK L +   L+VG+ +D E    KG  V T+ ER  
Sbjct: 90  KNVVIYADGVYDMLHLGHMKQLEQAKKLFENTTLIVGVTSDNETKLFKGQVVQTLEERTE 149

Query: 121 LVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDP------------------ 162
            +  ++WVDE+I+  P+ +T +FL +    YKIDYV H D P                  
Sbjct: 150 TLKHIRWVDEIISPCPWVVTPEFLEK----YKIDYVAHDDIPYANNQKKKKKKKSKGKSF 205

Query: 163 CLLPDGTDAYAAAKKAGRYKQIKRTEGVSSTDIVGRIMSSLKD 205
               +  D YA  K+AG++K  +RTEGVS+TD++ RI+ + +D
Sbjct: 206 SFDEENEDIYAWLKRAGKFKATQRTEGVSTTDLIVRILKNYED 248



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 56/235 (23%), Positives = 106/235 (44%), Gaps = 26/235 (11%)

Query: 191 SSTDIVGRIMSSLK-----DQKTCEDQNGTDVKRQEESMSKDSHISQFLPTSRRIVQFSN 245
           S+ DI G+    +K     +Q    D N   V   ++    +S+      +S+   + + 
Sbjct: 24  SNNDINGKQKEHIKKGNSENQDVDPDTNPDAVPDDDDDDDDNSNDESEYESSQMDSEKNK 83

Query: 246 GKGPGPNARIVYIDGAFDLFHAGHVEILKRARELGD--FLLVGIHSDETVSEHRGNHYPI 303
           G        ++Y DG +D+ H GH++ L++A++L +   L+VG+ SD      +G    +
Sbjct: 84  GSIKNSKNVVIYADGVYDMLHLGHMKQLEQAKKLFENTTLIVGVTSDNETKLFKGQ--VV 141

Query: 304 MHLHERSLSVLACRHVDEVIIGAPWEITKDMITTFNISLVVHGTVAEKSLHSER------ 357
             L ER+ ++   R VDE+I   PW +T + +  + I  V H  +   +   ++      
Sbjct: 142 QTLEERTETLKHIRWVDEIISPCPWVVTPEFLEKYKIDYVAHDDIPYANNQKKKKKKKSK 201

Query: 358 -----------DPYEVPKSMGMFRLLESPKDITTTTVAQRILANHEAYEKRNAKK 401
                      D Y   K  G F+  +  + ++TT +  RIL N+E Y +R+ ++
Sbjct: 202 GKSFSFDEENEDIYAWLKRAGKFKATQRTEGVSTTDLIVRILKNYEDYIERSLQR 256


>CTPU_RAT (Q9QZC4) Choline-phosphate cytidylyltransferase B (EC
           2.7.7.15) (Phosphorylcholine transferase B)
           (CTP:phosphocholine cytidylyltransferase B) (CT B) (CCT
           B) (CCT-beta)
          Length = 369

 Score =  108 bits (271), Expect = 2e-23
 Identities = 62/140 (44%), Positives = 84/140 (59%), Gaps = 6/140 (4%)

Query: 63  RRVRVYMDGCFDLMHYGHANALRQAKAL--GDELVVGLVNDEEILATKGPPVLTMAERLA 120
           R VRVY DG FDL H GHA AL QAK L     L+VG+ +D+     KG  V+  AER  
Sbjct: 75  RPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYE 134

Query: 121 LVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAKKAGR 180
            +   ++VDEVI DAP+ +T +FL +    +KID+V H D P       D Y   K+AG 
Sbjct: 135 ALRHCRYVDEVIRDAPWTLTPEFLEK----HKIDFVAHDDIPYSSAGSDDVYKHIKEAGM 190

Query: 181 YKQIKRTEGVSSTDIVGRIM 200
           +   +RTEG+S++DI+ RI+
Sbjct: 191 FVPTQRTEGISTSDIITRIV 210



 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 57/165 (34%), Positives = 91/165 (54%), Gaps = 9/165 (5%)

Query: 256 VYIDGAFDLFHAGHVEILKRAREL--GDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSV 313
           VY DG FDLFH+GH   L +A+ L    +LLVG+ SD+   + +G  + +M+  ER  ++
Sbjct: 79  VYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKG--FTVMNEAERYEAL 136

Query: 314 LACRHVDEVIIGAPWEITKDMITTFNISLVVHGTVAEKSLHSERDPYEVPKSMGMFRLLE 373
             CR+VDEVI  APW +T + +    I  V H  +   S  S+ D Y+  K  GMF   +
Sbjct: 137 RHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSD-DVYKHIKEAGMFVPTQ 195

Query: 374 SPKDITTTTVAQRILANHEAYEKRNAKKSQSEKR----YYEEKNY 414
             + I+T+ +  RI+ +++ Y +RN ++  + K     +  EK Y
Sbjct: 196 RTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY 240


>CTPU_HUMAN (Q9Y5K3) Choline-phosphate cytidylyltransferase B (EC
           2.7.7.15) (Phosphorylcholine transferase B)
           (CTP:phosphocholine cytidylyltransferase B) (CT B) (CCT
           B) (CCT-beta)
          Length = 369

 Score =  108 bits (271), Expect = 2e-23
 Identities = 62/140 (44%), Positives = 84/140 (59%), Gaps = 6/140 (4%)

Query: 63  RRVRVYMDGCFDLMHYGHANALRQAKAL--GDELVVGLVNDEEILATKGPPVLTMAERLA 120
           R VRVY DG FDL H GHA AL QAK L     L+VG+ +D+     KG  V+  AER  
Sbjct: 75  RPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYE 134

Query: 121 LVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAKKAGR 180
            +   ++VDEVI DAP+ +T +FL +    +KID+V H D P       D Y   K+AG 
Sbjct: 135 ALRHCRYVDEVIRDAPWTLTPEFLEK----HKIDFVAHDDIPYSSAGSDDVYKHIKEAGM 190

Query: 181 YKQIKRTEGVSSTDIVGRIM 200
           +   +RTEG+S++DI+ RI+
Sbjct: 191 FVPTQRTEGISTSDIITRIV 210



 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 57/165 (34%), Positives = 91/165 (54%), Gaps = 9/165 (5%)

Query: 256 VYIDGAFDLFHAGHVEILKRAREL--GDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSV 313
           VY DG FDLFH+GH   L +A+ L    +LLVG+ SD+   + +G  + +M+  ER  ++
Sbjct: 79  VYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKG--FTVMNEAERYEAL 136

Query: 314 LACRHVDEVIIGAPWEITKDMITTFNISLVVHGTVAEKSLHSERDPYEVPKSMGMFRLLE 373
             CR+VDEVI  APW +T + +    I  V H  +   S  S+ D Y+  K  GMF   +
Sbjct: 137 RHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSD-DVYKHIKEAGMFVPTQ 195

Query: 374 SPKDITTTTVAQRILANHEAYEKRNAKKSQSEKR----YYEEKNY 414
             + I+T+ +  RI+ +++ Y +RN ++  + K     +  EK Y
Sbjct: 196 RTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRY 240


>CTPT_YEAST (P13259) Choline-phosphate cytidylyltransferase (EC
           2.7.7.15) (Phosphorylcholine transferase)
           (CTP:phosphocholine cytidylyltransferase) (CT) (CCT)
          Length = 424

 Score =  107 bits (266), Expect = 7e-23
 Identities = 65/181 (35%), Positives = 98/181 (53%), Gaps = 16/181 (8%)

Query: 63  RRVRVYMDGCFDLMHYGHANALRQAKALGDE--LVVGLVNDEEILATKGPPVLTMAERLA 120
           R +R+Y DG FDL H GH   L Q K       L+VG+ +D+     KG  VLT  +R  
Sbjct: 102 RPIRIYADGVFDLFHLGHMKQLEQCKKAFPNVTLIVGVPSDKITHKLKGLTVLTDKQRCE 161

Query: 121 LVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAKKAGR 180
            ++  +WVDEV+ +AP+ +T +FL     E+KIDYV H D P +  D  D Y   K+ G+
Sbjct: 162 TLTHCRWVDEVVPNAPWCVTPEFLL----EHKIDYVAHDDIPYVSADSDDIYKPIKEMGK 217

Query: 181 YKQIKRTEGVSSTDIVGRI--------MSSLKDQKTCEDQNGTDVKRQEESMSKDSHISQ 232
           +   +RT GVS++DI+ +I        M +     T ++ N + +K+ E    K  HI++
Sbjct: 218 FLTTQRTNGVSTSDIITKIIRDYDKYLMRNFARGATRQELNVSWLKKNELEFKK--HINE 275

Query: 233 F 233
           F
Sbjct: 276 F 276



 Score = 80.5 bits (197), Expect = 7e-15
 Identities = 63/231 (27%), Positives = 108/231 (46%), Gaps = 16/231 (6%)

Query: 176 KKAGRYKQIKRTEGVSSTDIVGRIMSSLKDQKTCEDQNGTDVKRQ---EESMSKDSHISQ 232
           KK    +Q + TE   + D         K+Q   +D   T  KR+   +E   K++  + 
Sbjct: 25  KKNKNKRQREETEEQDNED-----KDESKNQDENKDTQLTPRKRRRLTKEFEEKEARYTN 79

Query: 233 FLPTSRRIVQ---FSNGKGPGPNARIVYIDGAFDLFHAGHVEILKRAREL--GDFLLVGI 287
            LP   R  +   F     P      +Y DG FDLFH GH++ L++ ++      L+VG+
Sbjct: 80  ELPKELRKYRPKGFRFNLPPTDRPIRIYADGVFDLFHLGHMKQLEQCKKAFPNVTLIVGV 139

Query: 288 HSDETVSEHRGNHYPIMHLHERSLSVLACRHVDEVIIGAPWEITKDMITTFNISLVVHGT 347
            SD+   + +G    ++   +R  ++  CR VDEV+  APW +T + +    I  V H  
Sbjct: 140 PSDKITHKLKG--LTVLTDKQRCETLTHCRWVDEVVPNAPWCVTPEFLLEHKIDYVAHDD 197

Query: 348 VAEKSLHSERDPYEVPKSMGMFRLLESPKDITTTTVAQRILANHEAYEKRN 398
           +   S  S+ D Y+  K MG F   +    ++T+ +  +I+ +++ Y  RN
Sbjct: 198 IPYVSADSD-DIYKPIKEMGKFLTTQRTNGVSTSDIITKIIRDYDKYLMRN 247


>CTPT_RAT (P19836) Choline-phosphate cytidylyltransferase A (EC
           2.7.7.15) (Phosphorylcholine transferase A)
           (CTP:phosphocholine cytidylyltransferase A) (CT A) (CCT
           A) (CCT-alpha)
          Length = 367

 Score =  105 bits (263), Expect = 2e-22
 Identities = 61/141 (43%), Positives = 84/141 (59%), Gaps = 6/141 (4%)

Query: 62  KRRVRVYMDGCFDLMHYGHANALRQAKAL--GDELVVGLVNDEEILATKGPPVLTMAERL 119
           +R VRVY DG FDL H GHA AL QAK L     L+VG+ +DE     KG  V+   ER 
Sbjct: 74  ERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERY 133

Query: 120 ALVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAKKAG 179
             V   ++VDEV+ +AP+ +T +FL     E++ID+V H D P       D Y   K+AG
Sbjct: 134 DAVQHCRYVDEVVRNAPWTLTPEFLA----EHRIDFVAHDDIPYSSAGSDDVYKHIKEAG 189

Query: 180 RYKQIKRTEGVSSTDIVGRIM 200
            +   +RTEG+S++DI+ RI+
Sbjct: 190 MFAPTQRTEGISTSDIITRIV 210



 Score =  102 bits (254), Expect = 2e-21
 Identities = 57/165 (34%), Positives = 91/165 (54%), Gaps = 9/165 (5%)

Query: 256 VYIDGAFDLFHAGHVEILKRAREL--GDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSV 313
           VY DG FDLFH+GH   L +A+ L    +L+VG+ SDE     +G  + +M+ +ER  +V
Sbjct: 79  VYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKG--FTVMNENERYDAV 136

Query: 314 LACRHVDEVIIGAPWEITKDMITTFNISLVVHGTVAEKSLHSERDPYEVPKSMGMFRLLE 373
             CR+VDEV+  APW +T + +    I  V H  +   S  S+ D Y+  K  GMF   +
Sbjct: 137 QHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSD-DVYKHIKEAGMFAPTQ 195

Query: 374 SPKDITTTTVAQRILANHEAYEKRNAKKSQSEKR----YYEEKNY 414
             + I+T+ +  RI+ +++ Y +RN ++  + K     +  EK Y
Sbjct: 196 RTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY 240


>CTPT_HUMAN (P49585) Choline-phosphate cytidylyltransferase A (EC
           2.7.7.15) (Phosphorylcholine transferase A)
           (CTP:phosphocholine cytidylyltransferase A) (CT A) (CCT
           A) (CCT-alpha)
          Length = 367

 Score =  105 bits (263), Expect = 2e-22
 Identities = 61/141 (43%), Positives = 84/141 (59%), Gaps = 6/141 (4%)

Query: 62  KRRVRVYMDGCFDLMHYGHANALRQAKAL--GDELVVGLVNDEEILATKGPPVLTMAERL 119
           +R VRVY DG FDL H GHA AL QAK L     L+VG+ +DE     KG  V+   ER 
Sbjct: 74  ERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERY 133

Query: 120 ALVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAKKAG 179
             V   ++VDEV+ +AP+ +T +FL     E++ID+V H D P       D Y   K+AG
Sbjct: 134 DAVQHCRYVDEVVRNAPWTLTPEFLA----EHRIDFVAHDDIPYSSAGSDDVYKHIKEAG 189

Query: 180 RYKQIKRTEGVSSTDIVGRIM 200
            +   +RTEG+S++DI+ RI+
Sbjct: 190 MFAPTQRTEGISTSDIITRIV 210



 Score =  103 bits (256), Expect = 1e-21
 Identities = 63/202 (31%), Positives = 103/202 (50%), Gaps = 9/202 (4%)

Query: 219 RQEESMSKDSHISQFLPTSRRIVQFSNGKGPGPNARIVYIDGAFDLFHAGHVEILKRARE 278
           RQ    S +  +    P  R  ++ ++   P      VY DG FDLFH+GH   L +A+ 
Sbjct: 42  RQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKN 101

Query: 279 L--GDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSVLACRHVDEVIIGAPWEITKDMIT 336
           L    +L+VG+ SDE     +G  + +M+ +ER  +V  CR+VDEV+  APW +T + + 
Sbjct: 102 LFPNTYLIVGVCSDELTHNFKG--FTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLA 159

Query: 337 TFNISLVVHGTVAEKSLHSERDPYEVPKSMGMFRLLESPKDITTTTVAQRILANHEAYEK 396
              I  V H  +   S  S+ D Y+  K  GMF   +  + I+T+ +  RI+ +++ Y +
Sbjct: 160 EHRIDFVAHDDIPYSSAGSD-DVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYAR 218

Query: 397 RNAKKSQSEKR----YYEEKNY 414
           RN ++  + K     +  EK Y
Sbjct: 219 RNLQRGYTAKELNVSFINEKKY 240


>CTPT_MOUSE (P49586) Choline-phosphate cytidylyltransferase A (EC
           2.7.7.15) (Phosphorylcholine transferase A)
           (CTP:phosphocholine cytidylyltransferase A) (CT A) (CCT
           A) (CCT-alpha)
          Length = 367

 Score =  105 bits (261), Expect = 3e-22
 Identities = 61/141 (43%), Positives = 83/141 (58%), Gaps = 6/141 (4%)

Query: 62  KRRVRVYMDGCFDLMHYGHANALRQAKAL--GDELVVGLVNDEEILATKGPPVLTMAERL 119
           +R VRVY DG FDL H GHA AL QAK L     L+VG+ +DE     KG  V+   ER 
Sbjct: 74  ERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERY 133

Query: 120 ALVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAKKAG 179
             V   ++VDEV+ +AP+ +T +FL     E++ID+V H D P       D Y   K AG
Sbjct: 134 DAVQHCRYVDEVVRNAPWTLTPEFLA----EHRIDFVAHDDIPYSSAGSDDVYKHIKDAG 189

Query: 180 RYKQIKRTEGVSSTDIVGRIM 200
            +   +RTEG+S++DI+ RI+
Sbjct: 190 MFAPTQRTEGISTSDIITRIV 210



 Score =  102 bits (254), Expect = 2e-21
 Identities = 57/165 (34%), Positives = 91/165 (54%), Gaps = 9/165 (5%)

Query: 256 VYIDGAFDLFHAGHVEILKRAREL--GDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSV 313
           VY DG FDLFH+GH   L +A+ L    +L+VG+ SDE     +G  + +M+ +ER  +V
Sbjct: 79  VYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKG--FTVMNENERYDAV 136

Query: 314 LACRHVDEVIIGAPWEITKDMITTFNISLVVHGTVAEKSLHSERDPYEVPKSMGMFRLLE 373
             CR+VDEV+  APW +T + +    I  V H  +   S  S+ D Y+  K  GMF   +
Sbjct: 137 QHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSD-DVYKHIKDAGMFAPTQ 195

Query: 374 SPKDITTTTVAQRILANHEAYEKRNAKKSQSEKR----YYEEKNY 414
             + I+T+ +  RI+ +++ Y +RN ++  + K     +  EK Y
Sbjct: 196 RTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY 240


>CTPT_CRIGR (P49584) Choline-phosphate cytidylyltransferase A (EC
           2.7.7.15) (Phosphorylcholine transferase A)
           (CTP:phosphocholine cytidylyltransferase A) (CT A) (CCT
           A) (CCT-alpha)
          Length = 367

 Score =  103 bits (257), Expect = 8e-22
 Identities = 60/141 (42%), Positives = 83/141 (58%), Gaps = 6/141 (4%)

Query: 62  KRRVRVYMDGCFDLMHYGHANALRQAKALGDEL--VVGLVNDEEILATKGPPVLTMAERL 119
           +R VRVY DG FDL H GHA AL QAK L      +VG+ +DE     KG  V+   ER 
Sbjct: 74  ERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYPIVGVCSDELTHNFKGFTVMNENERY 133

Query: 120 ALVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAKKAG 179
             V   ++VDEV+ +AP+ +T +FL     E++ID+V H D P       D Y   K+AG
Sbjct: 134 DAVQHCRYVDEVVRNAPWTLTPEFLA----EHRIDFVAHDDIPYSSAGSDDVYKHIKEAG 189

Query: 180 RYKQIKRTEGVSSTDIVGRIM 200
            +   +RTEG+S++DI+ RI+
Sbjct: 190 MFAPTQRTEGISTSDIITRIV 210



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 56/165 (33%), Positives = 90/165 (53%), Gaps = 9/165 (5%)

Query: 256 VYIDGAFDLFHAGHVEILKRAREL--GDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSV 313
           VY DG FDLFH+GH   L +A+ L    + +VG+ SDE     +G  + +M+ +ER  +V
Sbjct: 79  VYADGIFDLFHSGHARALMQAKNLFPNTYPIVGVCSDELTHNFKG--FTVMNENERYDAV 136

Query: 314 LACRHVDEVIIGAPWEITKDMITTFNISLVVHGTVAEKSLHSERDPYEVPKSMGMFRLLE 373
             CR+VDEV+  APW +T + +    I  V H  +   S  S+ D Y+  K  GMF   +
Sbjct: 137 QHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSD-DVYKHIKEAGMFAPTQ 195

Query: 374 SPKDITTTTVAQRILANHEAYEKRNAKKSQSEKR----YYEEKNY 414
             + I+T+ +  RI+ +++ Y +RN ++  + K     +  EK Y
Sbjct: 196 RTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY 240


>CTPT_CAEEL (P49583) Putative choline-phosphate cytidylyltransferase
           (EC 2.7.7.15) (Phosphorylcholine transferase)
           (CTP:phosphocholine cytidylyltransferase) (CT) (CCT)
          Length = 362

 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 55/140 (39%), Positives = 81/140 (57%), Gaps = 6/140 (4%)

Query: 63  RRVRVYMDGCFDLMHYGHANALRQAKALGDE--LVVGLVNDEEILATKGPPVLTMAERLA 120
           R VR+Y DG +DL H+GHAN LRQ K +     L+VG+  D +    KG  V +  ER  
Sbjct: 79  RPVRIYADGIYDLFHHGHANQLRQVKKMFPNVYLIVGVCGDRDTHKYKGRTVTSEEERYD 138

Query: 121 LVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDDPCLLPDGTDAYAAAKKAGR 180
            V   ++VDEV  +AP+  T +FL  L    K+D++ H   P + P   D Y   ++ G 
Sbjct: 139 GVRHCRYVDEVYREAPWFCTVEFLKNL----KVDFIAHDAIPYVAPGEEDLYEKFRREGM 194

Query: 181 YKQIKRTEGVSSTDIVGRIM 200
           + + +RTEGVS++D+V RI+
Sbjct: 195 FLETERTEGVSTSDVVCRII 214



 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 46/153 (30%), Positives = 79/153 (51%), Gaps = 5/153 (3%)

Query: 256 VYIDGAFDLFHAGHVEILKRAREL--GDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSV 313
           +Y DG +DLFH GH   L++ +++    +L+VG+  D    +++G    +    ER   V
Sbjct: 83  IYADGIYDLFHHGHANQLRQVKKMFPNVYLIVGVCGDRDTHKYKGR--TVTSEEERYDGV 140

Query: 314 LACRHVDEVIIGAPWEITKDMITTFNISLVVHGTVAEKSLHSERDPYEVPKSMGMFRLLE 373
             CR+VDEV   APW  T + +    +  + H  +   +   E D YE  +  GMF   E
Sbjct: 141 RHCRYVDEVYREAPWFCTVEFLKNLKVDFIAHDAIPYVA-PGEEDLYEKFRREGMFLETE 199

Query: 374 SPKDITTTTVAQRILANHEAYEKRNAKKSQSEK 406
             + ++T+ V  RI+ +++ Y +RN ++  S K
Sbjct: 200 RTEGVSTSDVVCRIIRDYDKYVRRNLQRGYSPK 232


>HLDE_HAEDU (Q7VM30) Bifunctional protein hldE [Includes:
           D-beta-D-heptose 7-phosphate kinase (EC 2.7.1.-)
           (D-beta-D-heptose 7-phosphotransferase);
           D-beta-D-heptose 1-phosphate adenosyltransferase (EC
           2.7.7.-)]
          Length = 475

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 46/151 (30%), Positives = 77/151 (50%), Gaps = 12/151 (7%)

Query: 55  FHKKKSGKRRVRVYMDGCFDLMHYGHANALRQAKALGDELVVGLVNDEEILATKGP--PV 112
           F K+   +    V  +GCFD++H GH + L  A+ LGD L+V +  D+ +   KG   P+
Sbjct: 331 FTKEAKNRGEKIVMTNGCFDILHPGHVSYLENARKLGDRLIVAVNCDQSVKRLKGESRPI 390

Query: 113 LTMAERLALVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDD--PCLLPDGTD 170
            +++ R+A+++GL  VD VI     A  E    RL  E   D ++ G D  P  +    +
Sbjct: 391 NSLSARMAILAGLASVDWVI-----AFEEDTPQRLISEILPDVLVKGGDYKPEQIVGCQE 445

Query: 171 AYAAAKKAGRYKQIKRTEGVSSTDIVGRIMS 201
            +A     G  K +   +G S+TD++ +I +
Sbjct: 446 VWA---NGGNVKALNFEDGCSTTDVIKKIQA 473



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 32/88 (36%), Positives = 47/88 (53%), Gaps = 1/88 (1%)

Query: 236 TSRRIVQFSNGKGPGPNARIVYIDGAFDLFHAGHVEILKRARELGDFLLVGIHSDETVSE 295
           T  R+ QF+  +      +IV  +G FD+ H GHV  L+ AR+LGD L+V ++ D++V  
Sbjct: 324 TEERLKQFTK-EAKNRGEKIVMTNGCFDILHPGHVSYLENARKLGDRLIVAVNCDQSVKR 382

Query: 296 HRGNHYPIMHLHERSLSVLACRHVDEVI 323
            +G   PI  L  R   +     VD VI
Sbjct: 383 LKGESRPINSLSARMAILAGLASVDWVI 410


>HLDE_VIBVY (Q7MNY3) Bifunctional protein hldE [Includes:
           D-beta-D-heptose 7-phosphate kinase (EC 2.7.1.-)
           (D-beta-D-heptose 7-phosphotransferase);
           D-beta-D-heptose 1-phosphate adenosyltransferase (EC
           2.7.7.-)]
          Length = 476

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 49/147 (33%), Positives = 71/147 (47%), Gaps = 12/147 (8%)

Query: 57  KKKSGKRRVRVYMDGCFDLMHYGHANALRQAKALGDELVVGLVNDEEILATKGP--PVLT 114
           K    K    V  +GCFD++H GH + L  A  LGD L+V +  DE +   KGP  PV  
Sbjct: 333 KAAQAKGEKVVMTNGCFDILHAGHVSYLNNAAKLGDRLIVAVNTDESVKRLKGPGRPVNP 392

Query: 115 MAERLALVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDD--PCLLPDGTDAY 172
              R+A+++GL  VD V+       +E    RL  E   D ++ G D  P  +  G +  
Sbjct: 393 TDRRMAVLAGLGAVDWVV-----PFSEDTPQRLISEVLPDLLVKGGDYKPEDIAGGKEVI 447

Query: 173 AAAKKAGRYKQIKRTEGVSSTDIVGRI 199
           AA    G  K +   +G S+T+I+  I
Sbjct: 448 AA---GGEVKVLNFEDGCSTTEIIDAI 471



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 25/62 (40%), Positives = 41/62 (65%), Gaps = 1/62 (1%)

Query: 254 RIVYIDGAFDLFHAGHVEILKRARELGDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSV 313
           ++V  +G FD+ HAGHV  L  A +LGD L+V +++DE+V   +G   P+ +  +R ++V
Sbjct: 341 KVVMTNGCFDILHAGHVSYLNNAAKLGDRLIVAVNTDESVKRLKGPGRPV-NPTDRRMAV 399

Query: 314 LA 315
           LA
Sbjct: 400 LA 401


>HLDE_VIBVU (Q8DEH7) Bifunctional protein hldE [Includes:
           D-beta-D-heptose 7-phosphate kinase (EC 2.7.1.-)
           (D-beta-D-heptose 7-phosphotransferase);
           D-beta-D-heptose 1-phosphate adenosyltransferase (EC
           2.7.7.-)]
          Length = 476

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 49/147 (33%), Positives = 71/147 (47%), Gaps = 12/147 (8%)

Query: 57  KKKSGKRRVRVYMDGCFDLMHYGHANALRQAKALGDELVVGLVNDEEILATKGP--PVLT 114
           K    K    V  +GCFD++H GH + L  A  LGD L+V +  DE +   KGP  PV  
Sbjct: 333 KAAQAKGEKVVMTNGCFDILHAGHVSYLNNAAKLGDRLIVAVNTDESVKRLKGPGRPVNP 392

Query: 115 MAERLALVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDD--PCLLPDGTDAY 172
              R+A+++GL  VD V+       +E    RL  E   D ++ G D  P  +  G +  
Sbjct: 393 TDRRMAVLAGLGAVDWVV-----PFSEDTPQRLISEVLPDLLVKGGDYKPEDIAGGKEVI 447

Query: 173 AAAKKAGRYKQIKRTEGVSSTDIVGRI 199
           AA    G  K +   +G S+T+I+  I
Sbjct: 448 AA---GGEVKVLNFEDGCSTTEIIDAI 471



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 25/62 (40%), Positives = 41/62 (65%), Gaps = 1/62 (1%)

Query: 254 RIVYIDGAFDLFHAGHVEILKRARELGDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSV 313
           ++V  +G FD+ HAGHV  L  A +LGD L+V +++DE+V   +G   P+ +  +R ++V
Sbjct: 341 KVVMTNGCFDILHAGHVSYLNNAAKLGDRLIVAVNTDESVKRLKGPGRPV-NPTDRRMAV 399

Query: 314 LA 315
           LA
Sbjct: 400 LA 401


>HLDE_SHEON (Q8EAZ2) Bifunctional protein hldE [Includes:
           D-beta-D-heptose 7-phosphate kinase (EC 2.7.1.-)
           (D-beta-D-heptose 7-phosphotransferase);
           D-beta-D-heptose 1-phosphate adenosyltransferase (EC
           2.7.7.-)]
          Length = 476

 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 45/143 (31%), Positives = 75/143 (51%), Gaps = 20/143 (13%)

Query: 67  VYMDGCFDLMHYGHANALRQAKALGDELVVGLVNDEEI--LATKGPPVLTMAERLALVSG 124
           V  +GCFD++H GH + L+QAKALGD L+V + +D  +  L  +G PV  +  R+A+++G
Sbjct: 344 VMTNGCFDILHAGHVSYLKQAKALGDRLIVAVNDDASVKRLKGEGRPVNQVDRRMAVLAG 403

Query: 125 LKWVDEVI---TDAPYAITEQFLHRLF---HEYKIDYVIHGDDPCLLPDGTDAYAAAKKA 178
           L  VD V+    D P  I  + L  L     +YK++ +  G +                 
Sbjct: 404 LASVDWVVPFSEDTPQRIIARLLPDLLVKGGDYKVEDIAGGAE------------VISAG 451

Query: 179 GRYKQIKRTEGVSSTDIVGRIMS 201
           G+ + +   +G+S+T I+  IM+
Sbjct: 452 GQVQVLGFEDGISTTAIIQNIMA 474



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 40/136 (29%), Positives = 70/136 (51%), Gaps = 3/136 (2%)

Query: 254 RIVYIDGAFDLFHAGHVEILKRARELGDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSV 313
           R+V  +G FD+ HAGHV  LK+A+ LGD L+V ++ D +V   +G   P+  + +R ++V
Sbjct: 342 RVVMTNGCFDILHAGHVSYLKQAKALGDRLIVAVNDDASVKRLKGEGRPVNQV-DRRMAV 400

Query: 314 LACRHVDEVIIGAPWEITKDMITTFNISLVVHGTVAEKSLHSERDPYEVPKSMGMFRLLE 373
           LA     + ++    +  + +I      L+V G   +  +       EV  + G  ++L 
Sbjct: 401 LAGLASVDWVVPFSEDTPQRIIARLLPDLLVKG--GDYKVEDIAGGAEVISAGGQVQVLG 458

Query: 374 SPKDITTTTVAQRILA 389
               I+TT + Q I+A
Sbjct: 459 FEDGISTTAIIQNIMA 474


>HLDE_HELHP (Q7VFZ3) Bifunctional protein hldE [Includes:
           D-beta-D-heptose 7-phosphate kinase (EC 2.7.1.-)
           (D-beta-D-heptose 7-phosphotransferase);
           D-beta-D-heptose 1-phosphate adenosyltransferase (EC
           2.7.7.-)]
          Length = 482

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 28/71 (39%), Positives = 46/71 (64%)

Query: 253 ARIVYIDGAFDLFHAGHVEILKRARELGDFLLVGIHSDETVSEHRGNHYPIMHLHERSLS 312
           ++IV+ +G FD+ H GH+  L +AR+LGD L+VG++ D+++   +G   PI  LH R+L 
Sbjct: 346 SKIVFTNGCFDILHIGHLSYLNKARDLGDILIVGLNDDDSIKRLKGKERPINTLHNRALM 405

Query: 313 VLACRHVDEVI 323
           +     VD V+
Sbjct: 406 LAGLECVDYVV 416



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 40/117 (34%), Positives = 62/117 (52%), Gaps = 13/117 (11%)

Query: 50  SNSGIFHKKKSGKRRVRVYMDGCFDLMHYGHANALRQAKALGDELVVGLVNDEEILATKG 109
           S   +F   K  K+   V+ +GCFD++H GH + L +A+ LGD L+VGL +D+ I   KG
Sbjct: 332 SQESLFTLLKDLKQSKIVFTNGCFDILHIGHLSYLNKARDLGDILIVGLNDDDSIKRLKG 391

Query: 110 P--PVLTMAERLALVSGLKWVDEVIT---DAPYAITEQFLHRLFHEYKIDYVIHGDD 161
              P+ T+  R  +++GL+ VD V++   D P          L    K D ++ G D
Sbjct: 392 KERPINTLHNRALMLAGLECVDYVVSFCQDTPL--------ELIKAIKPDVLVKGGD 440


>HLDE_VIBPA (Q87SJ9) Bifunctional protein hldE [Includes:
           D-beta-D-heptose 7-phosphate kinase (EC 2.7.1.-)
           (D-beta-D-heptose 7-phosphotransferase);
           D-beta-D-heptose 1-phosphate adenosyltransferase (EC
           2.7.7.-)]
          Length = 476

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 48/147 (32%), Positives = 74/147 (49%), Gaps = 13/147 (8%)

Query: 58  KKSGKRRVRVYM-DGCFDLMHYGHANALRQAKALGDELVVGLVNDEEILATKGP--PVLT 114
           KK+  R  +V M +GCFD++H GH + L  A  LGD L+V +  DE +   KGP  PV  
Sbjct: 333 KKARARGEKVVMTNGCFDILHAGHVSYLNHAAELGDRLIVAVNTDESVKRLKGPGRPVNP 392

Query: 115 MAERLALVSGLKWVDEVITDAPYAITEQFLHRLFHEYKIDYVIHGDD--PCLLPDGTDAY 172
              R+A+++GL  VD V+       +E    RL  E     ++ G D  P  +  G +  
Sbjct: 393 TDRRMAVLAGLGAVDWVV-----PFSEDTPQRLISEVLPSMLVKGGDYKPEEIAGGKEVI 447

Query: 173 AAAKKAGRYKQIKRTEGVSSTDIVGRI 199
           AA    G  + +   +G S+++I+  I
Sbjct: 448 AA---GGEVRVLNFEDGCSTSEIINAI 471



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 30/93 (32%), Positives = 54/93 (57%), Gaps = 1/93 (1%)

Query: 254 RIVYIDGAFDLFHAGHVEILKRARELGDFLLVGIHSDETVSEHRGNHYPIMHLHERSLSV 313
           ++V  +G FD+ HAGHV  L  A ELGD L+V +++DE+V   +G   P+ +  +R ++V
Sbjct: 341 KVVMTNGCFDILHAGHVSYLNHAAELGDRLIVAVNTDESVKRLKGPGRPV-NPTDRRMAV 399

Query: 314 LACRHVDEVIIGAPWEITKDMITTFNISLVVHG 346
           LA     + ++    +  + +I+    S++V G
Sbjct: 400 LAGLGAVDWVVPFSEDTPQRLISEVLPSMLVKG 432


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.319    0.137    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,060,461
Number of Sequences: 164201
Number of extensions: 2277047
Number of successful extensions: 5695
Number of sequences better than 10.0: 95
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 5447
Number of HSP's gapped (non-prelim): 186
length of query: 418
length of database: 59,974,054
effective HSP length: 113
effective length of query: 305
effective length of database: 41,419,341
effective search space: 12632899005
effective search space used: 12632899005
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)