BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0437b.7
(824 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_657286.1| Viral A-type inclusion protein repeat, putative... 172 4e-41
gb|AAX80557.1| hypothetical protein, conserved [Trypanosoma brucei] 172 5e-41
pir||S51364 sperm tail-specific protein mst101(2) - fruit fly (... 168 6e-40
emb|CAA51876.1| mst101(2) [Drosophila hydei] gi|730072|sp|Q08696... 168 6e-40
ref|XP_653447.1| Viral A-type inclusion protein repeat, putative... 167 2e-39
gb|AAX79229.1| hypothetical protein, conserved [Trypanosoma brucei] 158 8e-37
ref|XP_657028.1| myosin heavy chain [Entamoeba histolytica HM-1:... 155 4e-36
gb|EAA53821.1| hypothetical protein MG09571.4 [Magnaporthe grise... 155 4e-36
ref|XP_654864.1| hypothetical protein 42.t00003 [Entamoeba histo... 155 7e-36
gb|AAB48065.1| myosin heavy chain [Entamoeba histolytica] gi|749... 154 1e-35
emb|CAG77705.1| unnamed protein product [Yarrowia lipolytica CLI... 153 3e-35
emb|CAA98621.1| USO1 [Saccharomyces cerevisiae] gi|6320145|ref|N... 152 3e-35
emb|CAA38253.1| Uso1 protein [Saccharomyces cerevisiae] 152 3e-35
emb|CAA98620.1| USO1 [Saccharomyces cerevisiae] 152 3e-35
gb|AAB00143.1| putative 152 3e-35
ref|NP_504584.1| immunoglobulin-like and fibronectin, type III a... 149 3e-34
pir||T34418 hypothetical protein F12F3.3 - Caenorhabditis elegans 149 3e-34
gb|AAN61518.1| 2MDa_2 protein [Caenorhabditis elegans] 149 3e-34
gb|AAN61517.1| 2MDa_1 protein [Caenorhabditis elegans] 149 3e-34
gb|AAF58087.2| CG18255-PD, isoform D [Drosophila melanogaster] g... 148 8e-34
>ref|XP_657286.1| Viral A-type inclusion protein repeat, putative [Entamoeba
histolytica HM-1:IMSS] gi|56474542|gb|EAL51907.1| Viral
A-type inclusion protein repeat, putative [Entamoeba
histolytica HM-1:IMSS]
Length = 1387
Score = 172 bits (436), Expect = 4e-41
Identities = 199/888 (22%), Positives = 406/888 (45%), Gaps = 117/888 (13%)
Query: 6 AVIPEPANCCSKCE-ELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQ 64
+V+ E K E E++ KC+ + L ++ EK ++ L K+ K I + +
Sbjct: 379 SVMKEKKEEAEKAEREMRMKCQN----ESTLMGIIEEFEKSVKELNDRIKEKNKQIDDYE 434
Query: 65 A---QRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKV 121
+ K E K I L++E+ L + +KLK+ + ++ + L++ K
Sbjct: 435 KTIEENKEDFEAKELI---IQQLKDEIIQLTNTEQKLKEQLEIKEKE------LQEQTKE 485
Query: 122 VEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEV 181
V+ +N + ++ E+ I +++ +N++ + IQ+E + + E+ K+++ LEN +
Sbjct: 486 VKEQNQQQNIIQKKEQEIIDIKKKNEETIQLIQKEMEKERNELSIKIKE------LENII 539
Query: 182 SALKSENKKLKK--DILEEQAQRKVA-MEGKLEISNAFAALENEVSALKSENKKLKQDI- 237
S + E K+K+ D E++ QR M + EI+N + E++ +K EN + K I
Sbjct: 540 SGKEEEMNKIKEIHDYKEKEIQRITEKMNKETEINNK---TQQELNKIKEENNEYKNQIN 596
Query: 238 -----------------LDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLES 280
L+ + K LK+ E+ + + VK L+K IE +
Sbjct: 597 TLEIEIKTKEEEKGTTELELKENQKSIQELKELKEQERINKEIKEKEVKELQKIIEEWKV 656
Query: 281 ENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKD--ILEEQAQR 338
+ K+ K+ ++E +++ E K ++ E EV L E K+ K+ I++E+ +
Sbjct: 657 KEKEWKEQVEENQKEKEESEENKNQMKRIIEKKEEEVKGLNQEIDKINKENEIMKEKMKE 716
Query: 339 KVAMEGKLEI--------SNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKC 390
++G++E+ SN + E + LK + + +K D +E+ + + KKK
Sbjct: 717 LERIKGEIEVLKIKETGDSNEY---EKMIEELKKQIEIIKNDNEKERKNNEI--EQKKKN 771
Query: 391 EKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALE 450
E+ + L ++ +K IE L + ++LK+ EE + IE + ++ N L+
Sbjct: 772 EEFNQKEEELNNDIEKKKKEIEKLNKQIEELKQK-NEENTKENIEKQNQINQLN----LD 826
Query: 451 NEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCG 510
E + EST ++K+ +EE+ + + I EK +I++ + + +++ L I L+++
Sbjct: 827 KEKIMKELESTIMEKNQIEEERKKEQEINEK-KINDIITSKDTKINELNKSIIELKEEWN 885
Query: 511 AGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKL 570
N + L I E+ +N KE +K+ + E+KT E + + ++
Sbjct: 886 KKENNLNKSNQELTEQIIQKEEIINVTIKENENLKKVKEEIEKKTET-EINELQRKIKEN 944
Query: 571 LEAAKKIAPEKAVIPEPA-----NCCSKCDELKKKCEK-----------VAVGRNALRQA 614
E +I EK I + N + +E+K+K EK + +N L
Sbjct: 945 NEQINEINKEKENIQKEFEIQIDNKNKEINEIKEKNEKEINEIKIQIEEMNKEKNQLENL 1004
Query: 615 VKILEKGIENLESENKKLKKENE------------VSALKSEISALQQKCGAGAR----- 657
K LE E ++ ENKK ++EN+ + ++++EI++ +++ G +
Sbjct: 1005 KKQLENENEIIKKENKKKEEENKEMGYLIKENEKKIESIRNEINSKERELGTKIKLIEMI 1064
Query: 658 EGNGDV--EVLKAGISDTKKEVNRLKKEHVEEERIVA------DSERKTAVDERKNAAAE 709
+ D+ + K + + E+ RL+ + +++ + D ++K +++E+KN E
Sbjct: 1065 KNEKDIMEKDFKKEVDNKNIEIKRLQIDIEKKKNDITLIIQKNDEDKKKSIEEKKNLNQE 1124
Query: 710 ARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKK 769
K+ K +V+K+ ++ L + L+ N+ K ++ E + KE + +
Sbjct: 1125 IEKI----KSEKNDVQKEKEQILLEKEDLQSDFNKYKTQMENEKLQIKEEHENNITNLQN 1180
Query: 770 LLVEKINAESKIKKAQERSESELD---KKTADMEKQQAEEQKKLAEDK 814
+ EKIN +IK E+ +LD ++ + +K++ EE KK E K
Sbjct: 1181 EINEKINQNDEIKLQIEQLNKQLDELKQQLVETQKEKEEETKKYEEVK 1228
Score = 145 bits (365), Expect = 7e-33
Identities = 178/782 (22%), Positives = 361/782 (45%), Gaps = 89/782 (11%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEIS 78
+ELK+ EQ + + + VK L+K IE + + K+ K+ ++E Q +++ + E K ++
Sbjct: 624 QELKELKEQERINKEIKEKEVKELQKIIEEWKVKEKEWKEQVEENQKEKEESEENKNQMK 683
Query: 79 NTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVE-----GRNALRQAVK 133
E EV L E K+ ++ + + K +++K +V++ N + ++
Sbjct: 684 RIIEKKEEEVKGLNQEIDKINKENEIMKEKMKELERIKGEIEVLKIKETGDSNEYEKMIE 743
Query: 134 ILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKK 193
L+K+IE ++++N+K +K+ + EQ ++ E K E+ L N++ K E +KL K
Sbjct: 744 ELKKQIEIIKNDNEKERKNNEIEQKKKNEEFNQKEEE------LNNDIEKKKKEIEKLNK 797
Query: 194 DILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKK 253
I E + + + + +E +N+++ L + +K+ +++ + + +KK
Sbjct: 798 QIEELKQKNEENTKENIE-------KQNQINQLNLDKEKIMKELESTIMEKNQIEEERKK 850
Query: 254 CEKVVEGR-----NALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISN 308
+++ E + + + L K I L+ E K + ++ + + + +I K EI N
Sbjct: 851 EQEINEKKINDIITSKDTKINELNKSIIELKEEWNKKENNLNKSNQELTEQIIQKEEIIN 910
Query: 309 AFAALENEVSALKSE-NKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENK 367
+ +K E KK + +I E Q + K E EI+ ++ E ++ +NK
Sbjct: 911 VTIKENENLKKVKEEIEKKTETEINELQRKIKENNEQINEINKEKENIQKEFE-IQIDNK 969
Query: 368 KLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQE 427
+ + ++E+ + K +++K + E++ + +N L K LE E ++ ENKK K++ +
Sbjct: 970 NKEINEIKEKNE-KEINEIKIQIEEMNKEKNQLENLKKQLENENEIIKKENKK-KEEENK 1027
Query: 428 EQAQRKIEIEGKLE-ISNAFAALENEVSALKS--ESTKLKKDILEEQAQIKVAIEEKLEI 484
E E E K+E I N + E E+ E K +KDI+E+ + K + +EI
Sbjct: 1028 EMGYLIKENEKKIESIRNEINSKERELGTKIKLIEMIKNEKDIMEKDFK-KEVDNKNIEI 1086
Query: 485 SNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKE---- 540
L+ ++ K++I + QK ++ + + L I + E N ++KE
Sbjct: 1087 KR----LQIDIEKKKNDITLIIQKNDEDKKKSIEEKKNLNQEIEKIKSEKNDVQKEKEQI 1142
Query: 541 LVEKEKIVAD-SERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKK 599
L+EKE + +D ++ KT ++ K E E I + I E N + DE+K
Sbjct: 1143 LLEKEDLQSDFNKYKTQMENEKLQIKE-----EHENNITNLQNEINEKIN---QNDEIKL 1194
Query: 600 KCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREG 659
+ E++ + L+Q + +E + + ++ KK EV K +I Q
Sbjct: 1195 QIEQLNKQLDELKQQL------VETQKEKEEETKKYEEV---KGQIDGAHQ--------- 1236
Query: 660 NGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKK 719
+VE +K +T++++N++KKE DE + EA++ L +
Sbjct: 1237 --EVENIK---KETEQQINQMKKE----------------CDEMQKTTFEAKEELRVQVE 1275
Query: 720 IAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAES 779
+E +++ ++ L+K+V E ++ E K + K EKKK+ + + +
Sbjct: 1276 SVKMIETKVSTQKVSNTKLKKRVEE--LERTIEKLKNERNEKEAFWEKKKMWMIEDEEDK 1333
Query: 780 KI 781
K+
Sbjct: 1334 KV 1335
Score = 125 bits (315), Expect = 4e-27
Identities = 180/848 (21%), Positives = 379/848 (44%), Gaps = 105/848 (12%)
Query: 23 KKCEQVVVGRNALRQAVKILEKG--IENLESENKKLKKDIQEEQAQRKVAIEGKLEISNT 80
K E++ +GR + V+ ++ IE LE +K+ E + + ++ ++N
Sbjct: 238 KVAEKIFLGRRERTKEVRRAKRDELIEELEKLMDICRKNTDELVKDKIEKL--RVNVANM 295
Query: 81 FAALENEVSALISENKKLKQDILEEQA---QGKICDQLKKCEKVVEGRNA---------- 127
LE V E ++ D++ ++ +GKI + + + ++V+ ++
Sbjct: 296 MEGLEM-VEVEEDEFDEMDNDMIIQELNIHKGKIDNMMLEAMELVKEESSTPIEIRGEDS 354
Query: 128 -----LRQAVKILEKRIENLESENKKLKKDIQE-EQAQRKIEIEGKLEKSNAFAALENEV 181
LR +K K+IE LE +K+ +E E+A+R++ ++ + E S +E
Sbjct: 355 QALEELRVQIKQKIKKIEELEKLVSVMKEKKEEAEKAEREMRMKCQNE-STLMGIIEEFE 413
Query: 182 SALKSENKKLKKDILEEQAQRKVAMEGKLEISNA---FAALENEVSALKSENKKLKQDIL 238
++K N ++K+ + K E K + L++E+ L + +KLK+ +
Sbjct: 414 KSVKELNDRIKEKNKQIDDYEKTIEENKEDFEAKELIIQQLKDEIIQLTNTEQKLKEQLE 473
Query: 239 DEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKV 298
++ + L+++ ++V E +N + ++ E+ I +++ +N++ + IQ+E + +
Sbjct: 474 IKEKE------LQEQTKEVKE-QNQQQNIIQKKEQEIIDIKKKNEETIQLIQKEMEKERN 526
Query: 299 EIEGKLEISNAFAALENEVSALKSENKKLKK--DILEEQAQRKVA-MEGKLEISNAFAAL 355
E+ K++ LEN +S + E K+K+ D E++ QR M + EI+N
Sbjct: 527 ELSIKIK------ELENIISGKEEEMNKIKEIHDYKEKEIQRITEKMNKETEINNK---T 577
Query: 356 ENEVSALKSENKKLKQDI------------------LEEQAQGKFCDQLKKKCEKVVEGR 397
+ E++ +K EN + K I LE + K +LK+ E+ +
Sbjct: 578 QQELNKIKEENNEYKNQINTLEIEIKTKEEEKGTTELELKENQKSIQELKELKEQERINK 637
Query: 398 NALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALK 457
+ VK L+K IE + + K+ K+ ++E Q +++ E K ++ E EV L
Sbjct: 638 EIKEKEVKELQKIIEEWKVKEKEWKEQVEENQKEKEESEENKNQMKRIIEKKEEEVKGLN 697
Query: 458 SESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGN 517
E K+ K+ ++EK++ E+ +K EI L+ K S E
Sbjct: 698 QEIDKINKE--------NEIMKEKMK----------ELERIKGEIEVLKIKETGDSNEYE 739
Query: 518 GDVEVLKAGI----SDTEKE--VNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLL 571
+E LK I +D EKE N ++++ +E + E ++++KK + K +
Sbjct: 740 KMIEELKKQIEIIKNDNEKERKNNEIEQKKKNEEFNQKEEELNNDIEKKKKEIEKLNKQI 799
Query: 572 EAAKKIAPEKAVIP-EPANCCSKC----DELKKKCEKVAVGRNALRQAVKILEKGIENLE 626
E K+ E E N ++ +++ K+ E + +N + + K E+ I +
Sbjct: 800 EELKQKNEENTKENIEKQNQINQLNLDKEKIMKELESTIMEKNQIEEERK-KEQEINEKK 858
Query: 627 SENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVE 686
+ K+ +++ L I L+++ N + L I ++ +N KE+
Sbjct: 859 INDIITSKDTKINELNKSIIELKEEWNKKENNLNKSNQELTEQIIQKEEIINVTIKENEN 918
Query: 687 EERIVADSERK--TAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNE 744
+++ + E+K T ++E + E + + K ++K+ E++ + K++NE
Sbjct: 919 LKKVKEEIEKKTETEINELQRKIKENNEQINEINKEKENIQKEF---EIQIDNKNKEINE 975
Query: 745 RKMKLAFELSKTKEATKRFEAEKKKL--LVEKINAESKIKKAQERSESELDKKTADMEKQ 802
K K E+++ K + EK +L L +++ E++I K + + + E +K+ + K
Sbjct: 976 IKEKNEKEINEIKIQIEEMNKEKNQLENLKKQLENENEIIKKENKKKEEENKEMGYLIK- 1034
Query: 803 QAEEQKKL 810
E +KK+
Sbjct: 1035 --ENEKKI 1040
Score = 46.6 bits (109), Expect = 0.003
Identities = 66/301 (21%), Positives = 133/301 (43%), Gaps = 46/301 (15%)
Query: 540 ELVEKEK---IVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCD- 595
ELV++E I E A++E + + K +E +K+ +V+ E K +
Sbjct: 337 ELVKEESSTPIEIRGEDSQALEELRVQIKQKIKKIEELEKLV---SVMKEKKEEAEKAER 393
Query: 596 ELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAG 655
E++ KC+ + L ++ EK ++ L N ++K++N+ +I ++
Sbjct: 394 EMRMKCQN----ESTLMGIIEEFEKSVKEL---NDRIKEKNK------QIDDYEKTI--- 437
Query: 656 AREGNGDVEVLKAGISDTKKEVNRLK--KEHVEEERIVADSERKTAVDERKNAAAEARKL 713
E D E + I K E+ +L ++ ++E+ + + E + E K + +
Sbjct: 438 -EENKEDFEAKELIIQQLKDEIIQLTNTEQKLKEQLEIKEKELQEQTKEVKEQNQQQNII 496
Query: 714 LEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAF----------ELSKTKEATKRF 763
+ ++I +K ++L Q +EK+ NE +K+ E++K KE
Sbjct: 497 QKKEQEIIDIKKKNEETIQLIQKEMEKERNELSIKIKELENIISGKEEEMNKIKEIHDYK 556
Query: 764 EAEKKKLLVEKINAESKI---------KKAQERSESELDKKTADMEKQQAEEQKKLAEDK 814
E E +++ EK+N E++I K +E +E + T ++E + EE+K E +
Sbjct: 557 EKEIQRI-TEKMNKETEINNKTQQELNKIKEENNEYKNQINTLEIEIKTKEEEKGTTELE 615
Query: 815 L 815
L
Sbjct: 616 L 616
>gb|AAX80557.1| hypothetical protein, conserved [Trypanosoma brucei]
Length = 1378
Score = 172 bits (435), Expect = 5e-41
Identities = 205/819 (25%), Positives = 366/819 (44%), Gaps = 85/819 (10%)
Query: 22 KKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTF 81
+K +V A A K + +E LE+ K+ K D + ++A +K++ ++ +T
Sbjct: 373 QKNNMNIVTDETAFNTATK--KASMERLETRQKRSKTDGERKRA-KKLSARSRMREKDTT 429
Query: 82 AALENEVSALISENKKLKQDILEEQAQGKICDQL--KKCEKVVEGRNALRQAV-KILEKR 138
A E + +E + ++ EE A+ + ++ KK E+ + A +A K E+
Sbjct: 430 AKKAEEAARKKAEEEAARKKAEEEAARKRAEEEAARKKAEEEAARKKAEEEAARKKAEEE 489
Query: 139 IENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEE 198
+E + +K +EE A++K E E +K+ E E + K+E + +K EE
Sbjct: 490 AARKRAEEEAARKKAEEEAARKKAEEEAARKKA------EEEAARKKAEEEAARKKAEEE 543
Query: 199 QAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVV 258
A++K E A + E A + + +K+++ A+ K + +KK E+
Sbjct: 544 AARKKAEEEA--------ARKKAEEEAARKKAEKMRKRAQARNARMKAEEAARKKAEEEA 595
Query: 259 EGRNALRQAV-KILEKGIENLESENKKLKKDIQEEHAQRKVEIEG---KLEISNAFAALE 314
+ A +A K E+ +E + +K +EE A++K E E K E A E
Sbjct: 596 ARKRAEEEAARKKAEEEAARKRAEEEAARKRAEEEAARKKAEEEAARKKAEEEAARKKAE 655
Query: 315 NEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDIL 374
EV+ ++E + +K EE A++K E A + E A + + +K+++
Sbjct: 656 EEVARKRAEEEAARKKAEEEAARKKAEEEA--------ARKKAEEEAARKKAEKMRKRAQ 707
Query: 375 EEQAQGKFCDQLKKKCEKVVEGRNALRQAV-KILEKGIENLESENKKLKKDIQEEQAQRK 433
+A+ K + +KK E+ + A +A K E+ +E + +K +EE A+++
Sbjct: 708 ARKARMKAEEAARKKAEEEAARKKAEEEAARKKAEEEAARKRAEEEAARKKAEEEAARKR 767
Query: 434 IEIEG---KLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKV---AIEEKLEISNA 487
E E K E A E E + K+E +K EE A+ K A ++ E A
Sbjct: 768 AEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKRAEEEAA 827
Query: 488 FAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKI 547
E E + K+E A ++K + + E + E+ +E ++K
Sbjct: 828 RKRAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAE--EEAARKKAEEEAARKKA 885
Query: 548 VADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVG 607
++ RK A +E + AE EAA+K A E+A + A K E +K K A
Sbjct: 886 EEEAARKKAEEEAARKKAEE----EAARKRAEEEAA-RKKAERARKLAEARKTLRKRA-N 939
Query: 608 RNALRQAVKILEKGIEN----LESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDV 663
+ A R A K+ +++ + E +++K E + +K+E A + K D
Sbjct: 940 KGARRMAEKVSRNQLQSDAWTKKEEAERMKAEEDAERMKAEEDAERMKA-------EEDA 992
Query: 664 EVLKAGISDTKKEVNRLKKEHVEEERIVA--DSERKTAVDERKNAAAEARKLLEAPKKIA 721
E +KA ++E R+K E E ER+ A D+ER A +E AE K E +++
Sbjct: 993 ERMKA-----EEEAERMKAEE-EAERMKAEEDAERMKAEEE-----AERMKAEEEAERMK 1041
Query: 722 AE--VEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAES 779
AE E+ A+ E ++ E++ K + E K +E +R +AE++ E++ AE
Sbjct: 1042 AEEDAERVEAEEEAERMKAEEEAERMKAEEEAERMKAEEEAERMKAEEE---AERMKAEE 1098
Query: 780 KIK--KAQERS-------ESELDKKTADMEKQQAEEQKK 809
++K KA+E + E+E K D E+ +AEE+ K
Sbjct: 1099 EVKRMKAEEEAERMKAEEEAERMKAEEDAERMKAEEEVK 1137
Score = 142 bits (359), Expect = 3e-32
Identities = 160/711 (22%), Positives = 299/711 (41%), Gaps = 58/711 (8%)
Query: 121 VVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENE 180
+V A A K + +E LE+ K+ K D + ++A +K+ ++ + + A E
Sbjct: 379 IVTDETAFNTATK--KASMERLETRQKRSKTDGERKRA-KKLSARSRMREKDTTAKKAEE 435
Query: 181 VSALKSENKKLKKDILEEQAQRKVAMEG---KLEISNAFAALENEVSALKSENKKLKQDI 237
+ K+E + +K EE A+++ E K E A E E + K+E + ++
Sbjct: 436 AARKKAEEEAARKKAEEEAARKRAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKRA 495
Query: 238 LDEQAQGKFCDRLKKKCEKVVEGRNALRQAV-KILEKGIENLESENKKLKKDIQEEHAQR 296
+E A +KK E+ + A +A K E+ ++E + +K +EE A++
Sbjct: 496 EEEAA--------RKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARK 547
Query: 297 KVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALE 356
K E E A E E + K+E + + + + + A K E A E
Sbjct: 548 KAEEEA------ARKKAEEEAARKKAEKMRKRAQARNARMKAEEAARKKAEEEAARKRAE 601
Query: 357 NEVSALKSENKKLKQDILEEQAQGKFCDQL-KKKCEKVVEGRNALRQAV-KILEKGIENL 414
E + K+E + ++ EE A+ + ++ +KK E+ + A +A K E+ +
Sbjct: 602 EEAARKKAEEEAARKRAEEEAARKRAEEEAARKKAEEEAARKKAEEEAARKKAEEEVARK 661
Query: 415 ESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQI 474
+E + +K +EE A++K E E A + E A + ++ K++K +A++
Sbjct: 662 RAEEEAARKKAEEEAARKKAEEEA--------ARKKAEEEAARKKAEKMRKRAQARKARM 713
Query: 475 KV--AIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEK 532
K A +K E A E E + K+E A +++ + + E + E+
Sbjct: 714 KAEEAARKKAEEEAARKKAEEEAARKKAEEEAARKRAEEEAARKKAEEEAARKRAE--EE 771
Query: 533 EVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCS 592
+E ++K ++ RK A +E + AE + A++ A K E A +
Sbjct: 772 AARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKRAEEEAARKRA 831
Query: 593 KCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKC 652
+ + +KK E+ A + A +A + + E E + K E E + K+E A ++K
Sbjct: 832 EEEAARKKAEEEAARKKAEEEAAR------KKAEEEAARKKAEEEAARKKAEEEAARKKA 885
Query: 653 GAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDE-----RKNAA 707
A + E + KK ++ EEE +ER + E RK A
Sbjct: 886 EEEAARKKAEEEAAR------KKAEEEAARKRAEEEAARKKAERARKLAEARKTLRKRAN 939
Query: 708 AEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAE- 766
AR++ E + + + K E ++ E+ K + E K +E +R +AE
Sbjct: 940 KGARRMAEKVSRNQLQSDAWTKKEEAERMKAEEDAERMKAEEDAERMKAEEDAERMKAEE 999
Query: 767 -----KKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAE 812
K + E++ AE ++ + E+E K + E+ +AEE + E
Sbjct: 1000 EAERMKAEEEAERMKAEEDAERMKAEEEAERMKAEEEAERMKAEEDAERVE 1050
Score = 138 bits (348), Expect = 6e-31
Identities = 196/803 (24%), Positives = 345/803 (42%), Gaps = 98/803 (12%)
Query: 2 ASEKAVIPEPANCCSKCEELKKKCEQVVVGRNALRQAV-KILEKGIENLESENKKLKKDI 60
A+ K E A ++ E +KK E+ + A +A K E+ ++E + +K
Sbjct: 454 AARKRAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKRAEEEAARKKAEEEAARKKA 513
Query: 61 QEEQAQRKVAIEGKLEISNTFAA---LENEVSALISENKKLKQDILEEQAQGKICDQLKK 117
+EE A++K E + + AA E E + +E + ++ EE A+ K +K
Sbjct: 514 EEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKA----EK 569
Query: 118 CEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAA- 176
K + RNA +A + K+ +E + +K +EE A++K E E +++ AA
Sbjct: 570 MRKRAQARNARMKAEEAARKK-----AEEEAARKRAEEEAARKKAEEEAARKRAEEEAAR 624
Query: 177 --LENEVSALKSENKKLKKDILEEQAQRKVAME---GKLEISNAFAALENEVSALKSENK 231
E E + K+E + +K EE A++K E + E A E E + K+E +
Sbjct: 625 KRAEEEAARKKAEEEAARKKAEEEAARKKAEEEVARKRAEEEAARKKAEEEAARKKAEEE 684
Query: 232 KLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQE 291
++ +E+A K ++++K+ + A A K E+ ++E + +K +E
Sbjct: 685 AARKKA-EEEAARKKAEKMRKRAQARKARMKAEEAARKKAEEEAARKKAEEEAARKKAEE 743
Query: 292 EHAQRKVEIEG---KLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEG---K 345
E A+++ E E K E A E E + K+E + +K EE A++K E K
Sbjct: 744 EAARKRAEEEAARKKAEEEAARKRAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKK 803
Query: 346 LEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQL-KKKCEKVVEGRNALRQAV 404
E A E E + ++E + ++ EE A+ K ++ +KK E+ + A +A
Sbjct: 804 AEEEAARKKAEEEAARKRAEEEAARKRAEEEAARKKAEEEAARKKAEEEAARKKAEEEAA 863
Query: 405 -KILEKGIENLESENKKLKKDIQEEQAQRKIEIEG---KLEISNAFAALENEVSALKSE- 459
K E+ ++E + +K +EE A++K E E K E A E E + K+E
Sbjct: 864 RKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKRAEEEAARKKAER 923
Query: 460 ----------------------STKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSA 497
+ K+ ++ L+ A K E+++ ++ E A
Sbjct: 924 ARKLAEARKTLRKRANKGARRMAEKVSRNQLQSDAWTKKEEAERMKAEEDAERMKAEEDA 983
Query: 498 -----------LKSEIAALQQKCG--AGSREGNGDVEVLKAGISDTEKEVNTLK-KELVE 543
+K+E A + K A + D E +KA E+E +K +E E
Sbjct: 984 ERMKAEEDAERMKAEEEAERMKAEEEAERMKAEEDAERMKA-----EEEAERMKAEEEAE 1038
Query: 544 KEKIVADSERKTAVDE--RKKAAAEARKLL---EAAKKIAPEKAV---IPEPANCCSKCD 595
+ K D+ER A +E R KA EA ++ EA + A E+A E A +
Sbjct: 1039 RMKAEEDAERVEAEEEAERMKAEEEAERMKAEEEAERMKAEEEAERMKAEEEAERMKAEE 1098
Query: 596 ELKK-KCEKVAVGRNALRQAVKI-LEKGIENLESEN--KKLKKENEVSALKSEISALQQK 651
E+K+ K E+ A A +A ++ E+ E +++E K++K E E +K+E A + K
Sbjct: 1099 EVKRMKAEEEAERMKAEEEAERMKAEEDAERMKAEEEVKRMKAEEEAERMKAEEEAERMK 1158
Query: 652 CGAGAREGNGDVE---VLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAA 708
GA N D E V + G+ + RI ++ E + +R A
Sbjct: 1159 AEGGAGRKNSDEEGCVVEEEGLGGNRASDG--------PPRIASNQECTLSEQQRHERA- 1209
Query: 709 EARKLLEAPKKIAAEVEKQIAKV 731
+KL K++ A ++ + KV
Sbjct: 1210 -RKKLERYRKQVMARNQRPVCKV 1231
Score = 125 bits (313), Expect = 7e-27
Identities = 159/650 (24%), Positives = 268/650 (40%), Gaps = 77/650 (11%)
Query: 179 NEVSALKSE--NKKLKKDILEEQAQRKVAMEGKLEI---SNAFAALENEVSALKSENKKL 233
N ALK + N + + IL K + + I AF + S + E ++
Sbjct: 344 NNGDALKQKRVNSSVSRPILSAFVDVKTFQKNNMNIVTDETAFNTATKKASMERLETRQK 403
Query: 234 KQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEH 293
+ E+ + K + EK + A A K E+ ++E + +K +EE
Sbjct: 404 RSKTDGERKRAKKLSARSRMREKDTTAKKAEEAARKKAEEEAARKKAEEEAARKRAEEEA 463
Query: 294 AQRKVEIEG---KLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEG---KLE 347
A++K E E K E A E E + ++E + +K EE A++K E K E
Sbjct: 464 ARKKAEEEAARKKAEEEAARKKAEEEAARKRAEEEAARKKAEEEAARKKAEEEAARKKAE 523
Query: 348 ISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQL-KKKCEKV---VEGRNALRQA 403
A E E + K+E + ++ EE A+ K ++ +KK EK+ + RNA +A
Sbjct: 524 EEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEKMRKRAQARNARMKA 583
Query: 404 VKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKL 463
+ K ++E + +K +EE A++K E E A E E + ++E
Sbjct: 584 EEAARK-----KAEEEAARKRAEEEAARKKAEEEA------ARKRAEEEAARKRAEEEAA 632
Query: 464 KKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVL 523
+K EE A+ +K E A E EV+ ++E A ++K + + E
Sbjct: 633 RKKAEEEAAR------KKAEEEAARKKAEEEVARKRAEEEAARKKAEEEAARKKAEEEAA 686
Query: 524 KAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLL---EAAKKIAPE 580
+ E+E K E + K + K RKKA EA + EAA+K A E
Sbjct: 687 R---KKAEEEAARKKAEKMRKRAQARKARMKAEEAARKKAEEEAARKKAEEEAARKKAEE 743
Query: 581 KAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSA 640
+A +K+ E+ A + A +A + + E E + K E E +
Sbjct: 744 EAA--------------RKRAEEEAARKKAEEEAAR------KRAEEEAARKKAEEEAAR 783
Query: 641 LKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAV 700
K+E A ++K A + E + KK ++ EEE +E + A
Sbjct: 784 KKAEEEAARKKAEEEAARKKAEEEAAR------KKAEEEAARKRAEEEAARKRAEEEAA- 836
Query: 701 DERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEAT 760
RK A EA A KK E ++ A+ E + E++ +K + K +E
Sbjct: 837 --RKKAEEEA-----ARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEE-- 887
Query: 761 KRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKL 810
EA +KK E +++ + A++R+E E +K A+ ++ AE +K L
Sbjct: 888 ---EAARKKAEEEAARKKAEEEAARKRAEEEAARKKAERARKLAEARKTL 934
Score = 115 bits (288), Expect = 6e-24
Identities = 143/640 (22%), Positives = 269/640 (41%), Gaps = 47/640 (7%)
Query: 191 LKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQ----GKF 246
L +++ E +Q +G + + EV ++ LKQ ++ F
Sbjct: 307 LPRNVPEMHSQGLNYGDGPVYSKDFVCQTPGEVERARNNGDALKQKRVNSSVSRPILSAF 366
Query: 247 CD--RLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKL 304
D +K +V A A K + +E LE+ K+ K D + + A +K+ ++
Sbjct: 367 VDVKTFQKNNMNIVTDETAFNTATK--KASMERLETRQKRSKTDGERKRA-KKLSARSRM 423
Query: 305 EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEG---KLEISNAFAALENEVSA 361
+ A E + K+E + +K EE A+++ E K E A E E +
Sbjct: 424 REKDTTAKKAEEAARKKAEEEAARKKAEEEAARKRAEEEAARKKAEEEAARKKAEEEAAR 483
Query: 362 LKSENKKLKQDILEEQAQGKFCDQL-KKKCEKVVEGRNALRQAVKILEKGIENLESENKK 420
K+E + ++ EE A+ K ++ +KK E+ + A +A + ++E +
Sbjct: 484 KKAEEEAARKRAEEEAARKKAEEEAARKKAEEEAARKKAEEEAAR--------KKAEEEA 535
Query: 421 LKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKV--AI 478
+K +EE A++K E E A + E A + ++ K++K A++K A
Sbjct: 536 ARKKAEEEAARKKAEEEA--------ARKKAEEEAARKKAEKMRKRAQARNARMKAEEAA 587
Query: 479 EEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLK 538
+K E A E E + K+E A +++ + + E + E+
Sbjct: 588 RKKAEEEAARKRAEEEAARKKAEEEAARKRAEEEAARKRAEEEAARKKAE--EEAARKKA 645
Query: 539 KELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELK 598
+E ++K + RK A +E + AE EAA+K A E+A A ++ + +
Sbjct: 646 EEEAARKKAEEEVARKRAEEEAARKKAEE----EAARKKAEEEA-----ARKKAEEEAAR 696
Query: 599 KKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGARE 658
KK EK+ A + +K E + E E + K E E + K+E A +++ A
Sbjct: 697 KKAEKMRKRAQARKARMKAEEAARKKAEEEAARKKAEEEAARKKAEEEAARKRAEEEAAR 756
Query: 659 GNGDVEVLKAGISDT---KKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLE 715
+ E + + KK ++ EEE +E + A + + AA + E
Sbjct: 757 KKAEEEAARKRAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEE 816
Query: 716 APKKIAAE-VEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEK 774
A +K A E ++ A+ E + E++ +K + K +E R +AE++ +K
Sbjct: 817 AARKRAEEEAARKRAEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKKAEEEAAR-KK 875
Query: 775 INAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAEDK 814
E+ KKA+E + + ++ A +K + E +K AE++
Sbjct: 876 AEEEAARKKAEEEAARKKAEEEAARKKAEEEAARKRAEEE 915
Score = 59.7 bits (143), Expect = 4e-07
Identities = 82/367 (22%), Positives = 144/367 (38%), Gaps = 54/367 (14%)
Query: 451 NEVSALKSE--STKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQK 508
N ALK + ++ + + IL +K + + I A E +QK
Sbjct: 344 NNGDALKQKRVNSSVSRPILSAFVDVKTFQKNNMNIVTDETAFNTATKKASMERLETRQK 403
Query: 509 CGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEAR 568
E + L A EK+ K E ++K ++ RK A +E + AE
Sbjct: 404 RSKTDGERKR-AKKLSARSRMREKDTTAKKAEEAARKKAEEEAARKKAEEEAARKRAEE- 461
Query: 569 KLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESE 628
EAA+K A E+A +KK E+ A + A +A + + E E
Sbjct: 462 ---EAARKKAEEEAA--------------RKKAEEEAARKKAEEEAAR------KRAEEE 498
Query: 629 NKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEE 688
+ K E E + K+E A ++K A KK ++ EEE
Sbjct: 499 AARKKAEEEAARKKAEEEAARKKAEEEAAR---------------KKAEEEAARKKAEEE 543
Query: 689 RIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMK 748
+ RK A +E AE + +K+ + + A+++ + +K E K
Sbjct: 544 -----AARKKAEEEAARKKAEEEAARKKAEKMRKRAQARNARMKAEEAARKKAEEEAARK 598
Query: 749 LAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQK 808
A E + K+A + EA +K+ E+ K+A+E + + ++ A +K + E +
Sbjct: 599 RAEEEAARKKAEE--EAARKRA-----EEEAARKRAEEEAARKKAEEEAARKKAEEEAAR 651
Query: 809 KLAEDKL 815
K AE+++
Sbjct: 652 KKAEEEV 658
>pir||S51364 sperm tail-specific protein mst101(2) - fruit fly (Drosophila hydei)
Length = 1390
Score = 168 bits (426), Expect = 6e-40
Identities = 205/809 (25%), Positives = 369/809 (45%), Gaps = 57/809 (7%)
Query: 17 KCEELKKKCEQVVVGRNALRQAVKILEKGI-ENLESENKKLKKDIQE--EQAQRKVAIEG 73
K E+ KK C+++ + + K E E +E KK +K +E E A++K E
Sbjct: 358 KEEDEKKACKELAKKKKEADEKKKCEEAANKEKKAAEKKKCEKAAKERKEAAEKKKCEE- 416
Query: 74 KLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVK 133
AA + + +A + ++L ++I ++ A+ K C + K EK R + K
Sbjct: 417 --------AAKKEKEAAERKKCEELAKNI-KKAAEKKKCKEAAKKEKEAAERKKCEELAK 467
Query: 134 ILEKRIENLESENKKLK-KDIQE----EQAQRKIEIEGKLEKSNAFAALENEVSALKSEN 188
++K E + E K K++ E E+ +KI+ +K A E E + K
Sbjct: 468 KIKKAAEKKKCEETAKKGKEVAERKKCEELAKKIKKAEIKKKCKKLAKKEKETAEKKKCE 527
Query: 189 KKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALK----SENKKLKQDILD--EQA 242
K KK +E A++K + + A + E SA K +E KK ++ + E A
Sbjct: 528 KAAKKR--KEAAEKKKCEKAAKKRKEAAEKKKCEKSAKKRKEAAEKKKCEKAAKERKEAA 585
Query: 243 QGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEG 302
+ K C+ KK EK V R + K ++K +E KK K+ ++E + E G
Sbjct: 586 EKKKCEEAAKK-EKEVAERKKCEELAKKIKKA-----AEKKKCKEAAKKEKEAAEREKCG 639
Query: 303 KLEISNAFAALENEVSAL-KSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSA 361
+L AA + + L K E + +K E+ A+++ K + + A A E E +
Sbjct: 640 ELAKKIKKAAEKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCAEA-AKKEKEAAE 698
Query: 362 LKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKL 421
K + K++ +E A+ K C++L KK +K E + + A K L+ NKK
Sbjct: 699 KKKCEEAAKKE--KEAAERKKCEELAKKIKKAAEKKKCKKLAKKKKAGEKNKLKKGNKKG 756
Query: 422 KKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEK 481
KK ++E++ R++ + E A + E A + + + +E+A+ K +
Sbjct: 757 KKALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTA 816
Query: 482 LEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKEL 541
+ A + E +A K + A ++KC +++ E K ++ +K+
Sbjct: 817 KKRKEAAEKKKCEKAAKKRKEEAEKKKCEKTAKKRKETAEKKKC------EKAAKKRKQA 870
Query: 542 VEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANC-CSKCDELKKK 600
EK+K ++++ E+KK A A+K E A+K E+A E KC+EL KK
Sbjct: 871 AEKKKCEKAAKKRKEAAEKKKCAEAAKKEKELAEKKKCEEAAKKEKEVAERKKCEELAKK 930
Query: 601 CEKVAVGRNALRQAVKILEKGIEN-LESENKKLKKENEVSALKSEISALQQKCGAGAREG 659
+K A + + A K + G +N L+ + K KK+ + KS+ +A ++KC A++
Sbjct: 931 IKKAAEKKKCKKLAKKEKKAGEKNKLKKKAGKGKKKCKKLGKKSKRAAEKKKCAEAAKKE 990
Query: 660 NGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKK 719
+A +E + +KE E+++ +++ E+K A+KL EA +K
Sbjct: 991 K------EAATKKKCEERAKKQKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEK 1044
Query: 720 IAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAES 779
E + +L++ +KQ ER KL E ++ K+ +R A+K+K EK E
Sbjct: 1045 KQCEERAK----KLKEAAEQKQCEERAKKLK-EAAEKKQCEER--AKKEKEAAEKKQCEE 1097
Query: 780 KIKKAQERSESELDKKTADMEKQQAEEQK 808
+ KK +E +E + ++ A EK+ AE+++
Sbjct: 1098 RAKKLKEAAEKKQCEERAKKEKEAAEKKR 1126
Score = 158 bits (400), Expect = 6e-37
Identities = 206/825 (24%), Positives = 355/825 (42%), Gaps = 79/825 (9%)
Query: 17 KCEELKKKCEQVVVGRNALRQAVKILEKGIENLESEN--KKLKKDIQEEQA---QRKVAI 71
KCEE KK E+ V R + K ++K E + + KK K+ + E+ +K+
Sbjct: 589 KCEEAAKK-EKEVAERKKCEELAKKIKKAAEKKKCKEAAKKEKEAAEREKCGELAKKIKK 647
Query: 72 EGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQA 131
+ + A E E + K K+ +E A+ K C + K EK + +A
Sbjct: 648 AAEKKKCKKLAKKEKETAEKKKCEKAAKKR--KEAAEKKKCAEAAKKEKEAAEKKKCEEA 705
Query: 132 VKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKL 191
K ++ E + E +L K I++ ++K + K +K+ E + LK NKK
Sbjct: 706 AKKEKEAAERKKCE--ELAKKIKKAAEKKKCKKLAKKKKAG-------EKNKLKKGNKKG 756
Query: 192 KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLK 251
KK + E++ R++A + E A + E A + + + E+A+ K C++
Sbjct: 757 KKALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTA 816
Query: 252 KKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFA 311
KK ++ E + + A K E E+E KK +K A+++ E K + A
Sbjct: 817 KKRKEAAEKKKCEKAAKKRKE------EAEKKKCEKT-----AKKRKETAEKKKCEKAAK 865
Query: 312 ALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQ 371
+ K E K+ +E A++K E A E E++ K + K+
Sbjct: 866 KRKQAAEKKKCEKAAKKR---KEAAEKKKCAEA--------AKKEKELAEKKKCEEAAKK 914
Query: 372 DILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQ 431
+ +E A+ K C++L KK +K E + + A K E E KLKK + + +
Sbjct: 915 E--KEVAERKKCEELAKKIKKAAEKKKCKKLAKK------EKKAGEKNKLKK--KAGKGK 964
Query: 432 RKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAAL 491
+K + GK S A + A K E K EE+A+ + EK + L
Sbjct: 965 KKCKKLGKK--SKRAAEKKKCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAKKL 1022
Query: 492 ENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLK-KELVEKEKIVAD 550
+ + E A + K A ++ + LK + E K KE EK++
Sbjct: 1023 KEAAEQKQCEERAKKLKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCEER 1082
Query: 551 SERKTAVDERKKAAAEARKLLEAA-KKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRN 609
++++ E+K+ A+KL EAA KK E+A + A +C+E K+ ++ A +
Sbjct: 1083 AKKEKEAAEKKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKRCEEAAKREKEAAEKKK 1142
Query: 610 ALRQAVKILE-----KGIENLESENKKLKKENEVSALKSEISALQ-QKCGAGAREGNGDV 663
A K E K E + E + +K+ A K E A Q +KC A++
Sbjct: 1143 CAEAAKKEKEATEKQKCAEAAKKEKEAAEKKKCAEAAKREKEAAQKKKCADLAKKEQEPA 1202
Query: 664 EVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEA--PKKIA 721
E+ K +E + +KE E+++ ++++ E+K A A+K EA KK A
Sbjct: 1203 EMKKC------EEAAKKEKEAAEKQKCAKAAKKEKEAAEKKKCAEAAKKEQEAAEKKKCA 1256
Query: 722 AEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFE----AEKKKLLVEKINA 777
+K+ + R+ ++ K + A + + KEA R + A+K K+ EK
Sbjct: 1257 EAAKKEKEAEKKRKCEKAEKAAALKRQCAKLVIRAKEAALRKKCAIIAKKAKMAAEKKEC 1316
Query: 778 ESKIKKAQERSE----SELDKKTADMEKQQ----AEEQKKLAEDK 814
E KKA+E E ++L KK + EK++ A+++K+ AE K
Sbjct: 1317 EKLAKKAKEAIEWKKCAKLAKKKREAEKKKCAKLAKKEKEAAEKK 1361
Score = 155 bits (392), Expect = 5e-36
Identities = 210/851 (24%), Positives = 363/851 (41%), Gaps = 68/851 (7%)
Query: 17 KCEELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLE 76
KCEEL KK ++ + + + A K E + + K +K+ E++ K A + K
Sbjct: 493 KCEELAKKIKKAEIKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCEKAAKKRKEA 552
Query: 77 ISNTFAALENEVSALISENKKLKQDILE--EQAQGKICDQLKKCEKVVEGRNALRQAVKI 134
+ +E KK ++ E E A+ K C++ K EK V R + K
Sbjct: 553 AEKKKCEKSAKKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKK 612
Query: 135 LEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSAL-KSENKKLKK 193
++K +E KK K+ ++E+ + E G+L K AA + + L K E + +K
Sbjct: 613 IKKA-----AEKKKCKEAAKKEKEAAEREKCGELAKKIKKAAEKKKCKKLAKKEKETAEK 667
Query: 194 DILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKK 253
E+ A+++ K + + A A E E + K + K++ E A+ K C+ L KK
Sbjct: 668 KKCEKAAKKRKEAAEKKKCAEA-AKKEKEAAEKKKCEEAAKKE--KEAAERKKCEELAKK 724
Query: 254 CEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAAL 313
+K E + + A K L+ NKK KK ++E+ R++ + E A
Sbjct: 725 IKKAAEKKKCKKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKKAAEKKKCKEAA 784
Query: 314 ENEVSAL---------KSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKS 364
+ E A K ++ +K E+ A+++ K + A + E K
Sbjct: 785 KKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAKKRKEEAEKKKC 844
Query: 365 ENKKLKQDILEEQAQGKFCDQL---------KKKCEKVVEGRNALRQAVKILEKGIENLE 415
E K+ +E A+ K C++ KKKCEK + R + K E + E
Sbjct: 845 EKTAKKR---KETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKE 901
Query: 416 SENKKL-------KKDIQE----EQAQRKIEIEGKLEISNAFAALEN---EVSALKSEST 461
KK +K++ E E+ +KI+ + + A E E + LK ++
Sbjct: 902 LAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKKLAKKEKKAGEKNKLKKKAG 961
Query: 462 KLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVE 521
K KK + + K A E+K + + A + + K E A +QK A ++ +
Sbjct: 962 KGKKKCKKLGKKSKRAAEKK-KCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAK 1020
Query: 522 VLKAGISDTEKEVNTLK-KELVEKEKIVADSERKTAVDERKKAAAEARKLLEAA-KKIAP 579
LK + E K KE EK++ +++ E+K+ A+KL EAA KK
Sbjct: 1021 KLKEAAEQKQCEERAKKLKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCE 1080
Query: 580 EKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGI-----ENLESENKKLKK 634
E+A + A +C+E KK ++ A + +A K E E + E + +K
Sbjct: 1081 ERAKKEKEAAEKKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKRCEEAAKREKEAAEK 1140
Query: 635 ENEVSALKSEISALQ-QKCGAGAREGNGDVEVLK-AGISDTKKEVNRLKK--EHVEEERI 690
+ A K E A + QKC A++ E K A + +KE + KK + ++E+
Sbjct: 1141 KKCAEAAKKEKEATEKQKCAEAAKKEKEAAEKKKCAEAAKREKEAAQKKKCADLAKKEQE 1200
Query: 691 VADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLA 750
A+ ++ +++ AAE +K +A KK EK+ + + ++Q K K A
Sbjct: 1201 PAEMKKCEEAAKKEKEAAEKQKCAKAAKKEKEAAEKK----KCAEAAKKEQEAAEKKKCA 1256
Query: 751 FELSKTKEATKRFEAEK-KKLLVEKINAESKIKKAQE---RSESELDKKTADM--EKQQA 804
K KEA K+ + EK +K K + +A+E R + + K A M EK++
Sbjct: 1257 EAAKKEKEAEKKRKCEKAEKAAALKRQCAKLVIRAKEAALRKKCAIIAKKAKMAAEKKEC 1316
Query: 805 EEQKKLAEDKL 815
E+ K A++ +
Sbjct: 1317 EKLAKKAKEAI 1327
Score = 150 bits (378), Expect = 2e-34
Identities = 212/794 (26%), Positives = 358/794 (44%), Gaps = 88/794 (11%)
Query: 47 ENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQ 106
+N E + K+L+++I +EQA+ + I G +++ + + AL + K L + ++E+
Sbjct: 291 KNDEKKEKELEREILKEQAEEEAKIRGVVKVKK-----KCKEKALKKKCKDLGRK-MKEE 344
Query: 107 AQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEG 166
A+ K C L K +K + + A ++ K + E++ KK + E+A K +
Sbjct: 345 AEKKKCAALAKKQKEEDEKKACKELAK------KKKEADEKK-----KCEEAANKEKKAA 393
Query: 167 KLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSAL 226
+ +K A E + K + KK+ +E A+RK E I A
Sbjct: 394 EKKKCEKAAKERKEAAEKKKCEEAAKKE--KEAAERKKCEELAKNIKKA----------- 440
Query: 227 KSENKKLKQDILDEQ--AQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESEN-K 283
+E KK K+ E+ A+ K C+ L KK +K E + A +KG E E + +
Sbjct: 441 -AEKKKCKEAAKKEKEAAERKKCEELAKKIKKAAEKKKCEETA----KKGKEVAERKKCE 495
Query: 284 KLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAME 343
+L K I +K EI+ K + A E E + K K KK +E A++K +
Sbjct: 496 ELAKKI------KKAEIKKKCK---KLAKKEKETAEKKKCEKAAKKR--KEAAEKKKCEK 544
Query: 344 GKLEISNAFAALENEVSALK----SENKKLKQDILE--EQAQGKFCDQLKKKCEKVVEGR 397
+ A + E SA K +E KK ++ E E A+ K C++ KK EK V R
Sbjct: 545 AAKKRKEAAEKKKCEKSAKKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKK-EKEVAER 603
Query: 398 NALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSAL- 456
+ K ++K +E KK K+ ++E+ + E G+L AA + + L
Sbjct: 604 KKCEELAKKIKKA-----AEKKKCKEAAKKEKEAAEREKCGELAKKIKKAAEKKKCKKLA 658
Query: 457 KSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREG 516
K E +K E+ A+ + EK + + A + K E AA ++K A ++
Sbjct: 659 KKEKETAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKEAAEKKKCEEAAKKEKEAAERKKC 718
Query: 517 NGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSER-KTAVDERKKA-------AAEAR 568
+ +K + + KK+ EK K+ +++ K A+ E+KK AAE +
Sbjct: 719 EELAKKIKKAAEKKKCKKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKKAAEKK 778
Query: 569 KLLEAAKKI--APEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLE 626
K EAAKK A EK + A K + KKKCEK A R + K EK + +
Sbjct: 779 KCKEAAKKEKEAAEKKKCEKTAKK-RKEEAEKKKCEKTAKKRKEAAEKKKC-EKAAKKRK 836
Query: 627 SENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKK---E 683
E +K K+ E +A K + +A ++KC A++ E K + K++ KK E
Sbjct: 837 EEAEK--KKCEKTAKKRKETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKKKCAE 894
Query: 684 HVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVN 743
++E+ +A+ ++ +++ AE +K E KKI EK+ K ++ EK+
Sbjct: 895 AAKKEKELAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKKLAKK---EKKAG 951
Query: 744 ERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQ----ERSESELDKKTADM 799
E K KL + K K+ K+ + K+ +K AE+ K+ + ++ E K+
Sbjct: 952 E-KNKLKKKAGKGKKKCKKLGKKSKRAAEKKKCAEAAKKEKEAATKKKCEERAKKQKEAA 1010
Query: 800 EKQQAEEQ-KKLAE 812
EK+Q EE+ KKL E
Sbjct: 1011 EKKQCEERAKKLKE 1024
Score = 138 bits (348), Expect = 6e-31
Identities = 195/724 (26%), Positives = 325/724 (43%), Gaps = 85/724 (11%)
Query: 108 QGKICDQLKKCEK-----VVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKI 162
+ + +L+ C K V E RN K L + + +E K +K ++
Sbjct: 214 KNRFTQKLEHCIKSEWADVCECRNFTEDERKRLAASYKCMGTETK-IKSICRKRVIAEMC 272
Query: 163 EIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENE 222
E G ++ S + + + K E K+L+++IL+EQA+ + + G +++ + +
Sbjct: 273 EAAGYVKSSEPKKKGKKKKNDEKKE-KELEREILKEQAEEEAKIRGVVKVKK-----KCK 326
Query: 223 VSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESEN 282
ALK + K L + + E+A+ K C L KK ++ E ++A K L K + + +
Sbjct: 327 EKALKKKCKDLGRK-MKEEAEKKKCAALAKKQKEEDE-----KKACKELAKKKKEADEKK 380
Query: 283 KKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAM 342
K + +E+ A K + E AA E + +A K + ++ K +E A+RK
Sbjct: 381 KCEEAANKEKKAAEKKKCEK--------AAKERKEAAEKKKCEEAAKKE-KEAAERKKCE 431
Query: 343 EGKLEISNAFAALENEVSALKSENKKLKQDILEEQ--AQGKFCDQLKKKCEKVVEGRNAL 400
E I A +E KK K+ +E+ A+ K C++L KK +K E +
Sbjct: 432 ELAKNIKKA------------AEKKKCKEAAKKEKEAAERKKCEELAKKIKKAAEKKKCE 479
Query: 401 RQAVKILEKGIENLESEN-KKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSE 459
A +KG E E + ++L K I++ + ++K + K E A + E +A K +
Sbjct: 480 ETA----KKGKEVAERKKCEELAKKIKKAEIKKKCKKLAKKEKETA-EKKKCEKAAKKRK 534
Query: 460 STKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGD 519
KK + + K A E+K + E SA K + AA ++KC ++E
Sbjct: 535 EAAEKKKCEKAAKKRKEAAEKK----------KCEKSAKKRKEAAEKKKCEKAAKERKEA 584
Query: 520 VEVLKAG-ISDTEKEVNTLKK---------ELVEKEKIVADSERKTAVDERKKAAAEARK 569
E K + EKEV KK + EK+K ++++ ER+K A+K
Sbjct: 585 AEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKEAAKKEKEAAEREKCGELAKK 644
Query: 570 LLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESEN 629
+ +AA+K +K E K KKKCEK A R + K E + E+
Sbjct: 645 IKKAAEKKKCKKLAKKE------KETAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKEAAE 698
Query: 630 KKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKK---EVNRLKKEHVE 686
KK+ E +A K + +A ++KC A++ E K KK E N+LKK + +
Sbjct: 699 ---KKKCEEAAKKEKEAAERKKCEELAKKIKKAAEKKKCKKLAKKKKAGEKNKLKKGNKK 755
Query: 687 EERIVADSERKTAVDERKNAAAEARKLLEAPK--KIAAEVEKQIAKVELRQVHLEKQVNE 744
++ A E+K + K AAE +K EA K K AAE +K + R+ EK+ E
Sbjct: 756 GKK--ALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAAEKKKCEKTAKKRKEEAEKKKCE 813
Query: 745 RKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQA 804
+ K E ++ K+ K A+K+K EK E KK +E +E + +K A KQ A
Sbjct: 814 KTAKKRKEAAEKKKCEK--AAKKRKEEAEKKKCEKTAKKRKETAEKKKCEKAAKKRKQAA 871
Query: 805 EEQK 808
E++K
Sbjct: 872 EKKK 875
Score = 125 bits (315), Expect = 4e-27
Identities = 198/804 (24%), Positives = 357/804 (43%), Gaps = 103/804 (12%)
Query: 53 NKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQG--K 110
+KK +K +EEQA+ + L++ A E S +++ L Q +++ G K
Sbjct: 68 DKKKQKQKEEEQAKIREYKRECLKVQKRVLAEEIRCSG--EKDRILIQGMMKCLTDGMKK 125
Query: 111 ICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEK 170
C ++ K + + + A++ A + +++ L KK ++ +E++ + EG ++
Sbjct: 126 ACTKIAKAKLIADKELAVQCAALSKKDKVKALL---KKCERKSKEKECNQNSPAEGDKDR 182
Query: 171 SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAA-LENEVS---AL 226
+ + + KS K+ E +A++ GK + N F LE+ + A
Sbjct: 183 T------KKGKTKGKSGGGNKKRSTKENRAKK-----GKKLVKNRFTQKLEHCIKSEWAD 231
Query: 227 KSENKKLKQDILDEQAQGKFC----DRLKKKCEKVV-----EGRNALRQAV-KILEKGIE 276
E + +D A C ++K C K V E ++ + K K +
Sbjct: 232 VCECRNFTEDERKRLAASYKCMGTETKIKSICRKRVIAEMCEAAGYVKSSEPKKKGKKKK 291
Query: 277 NLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQA 336
N E + K+L+++I +E A+ + +I G +++ + + ALK + K L + + EE
Sbjct: 292 NDEKKEKELEREILKEQAEEEAKIRGVVKVKK-----KCKEKALKKKCKDLGRKMKEEAE 346
Query: 337 QRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEG 396
++K A K + E+E A K KK K E + K C++ K +K E
Sbjct: 347 KKKCAALAKKQKE------EDEKKACKELAKKKK-----EADEKKKCEEAANKEKKAAEK 395
Query: 397 RNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSAL 456
+ +A K ++ E + E K ++E A+RK E I A + + +A
Sbjct: 396 KKC-EKAAKERKEAAEKKKCEEAAKK---EKEAAERKKCEELAKNIKKAAEKKKCKEAAK 451
Query: 457 KSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREG 516
K + +K E +IK A E+K + E +A K + A ++KC +++
Sbjct: 452 KEKEAAERKKCEELAKKIKKAAEKK----------KCEETAKKGKEVAERKKCEELAKK- 500
Query: 517 NGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKK 576
+ KA I K++ +KE EK+K ++++ E+KK A+K EAA+K
Sbjct: 501 -----IKKAEIKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCEKAAKKRKEAAEK 555
Query: 577 IAPEKAV-----IPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKK 631
EK+ E C E K+ EK A ++ K E L + KK
Sbjct: 556 KKCEKSAKKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKK 615
Query: 632 L--KKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEER 689
KK+ + +A K + +A ++KCG A++ + KA K++ + +KE E+++
Sbjct: 616 AAEKKKCKEAAKKEKEAAEREKCGELAKK------IKKAAEKKKCKKLAKKEKETAEKKK 669
Query: 690 IV-ADSERKTAVDERKNA--------AAEARKLLEAPKKI--AAEVEK--QIAKVELRQV 736
A +RK A +++K A AAE +K EA KK AAE +K ++AK +
Sbjct: 670 CEKAAKKRKEAAEKKKCAEAAKKEKEAAEKKKCEEAAKKEKEAAERKKCEELAKKIKKAA 729
Query: 737 HLEKQVNERKMKLAFELSKTKEATKRFEA---EKKK---LLVEKINAESKIKKAQERSES 790
+K K K A E +K K+ K+ + EKKK L +K + K K+A ++ +
Sbjct: 730 EKKKCKKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKKAAEKKKCKEAAKKEKE 789
Query: 791 ELDKKTADMEKQQAEEQKKLAEDK 814
+KK + + A+++K+ AE K
Sbjct: 790 AAEKKKCE---KTAKKRKEEAEKK 810
Score = 91.7 bits (226), Expect = 9e-17
Identities = 141/565 (24%), Positives = 242/565 (41%), Gaps = 53/565 (9%)
Query: 22 KKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTF 81
KKKCE+ R + K + + E+ KK K + + ++++A + K E +
Sbjct: 857 KKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKK--KCAEAAKKEKELAEKKKCEEA--- 911
Query: 82 AALENEVSALISENKKLKQ--DILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRI 139
A E EV+ E KK ++ +++ A+ K C +L K EK +N L++ +K+
Sbjct: 912 AKKEKEVA----ERKKCEELAKKIKKAAEKKKCKKLAKKEKKAGEKNKLKKKAGKGKKKC 967
Query: 140 ENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQ 199
+ L ++K+ + + +A +K + +K A + E + K ++ KK L+E
Sbjct: 968 KKLGKKSKRAAEKKKCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAKK--LKEA 1025
Query: 200 AQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVE 259
A++K E ++ A + E A KKLK E A+ K C+ KK ++ E
Sbjct: 1026 AEQKQCEERAKKLKEAAEKKQCEERA-----KKLK-----EAAEQKQCEERAKKLKEAAE 1075
Query: 260 GRNALRQAVKILEKGIEN-LESENKKLKKDIQ----EEHAQRKVEIEGKLEISNAFAALE 314
+ +A K E + E KKLK+ + EE A+++ E K A A E
Sbjct: 1076 KKQCEERAKKEKEAAEKKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKRCEEA-AKRE 1134
Query: 315 NEVSALK--SENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQD 372
E + K +E K +K+ E+Q + A + K E + E ++ KK D
Sbjct: 1135 KEAAEKKKCAEAAKKEKEATEKQKCAEAAKKEK-EAAEKKKCAEAAKREKEAAQKKKCAD 1193
Query: 373 IL---EEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILE-----KGIENLESENKKLKKD 424
+ +E A+ K C++ KK ++ E + + A K E K E + E + +K
Sbjct: 1194 LAKKEQEPAEMKKCEEAAKKEKEAAEKQKCAKAAKKEKEAAEKKKCAEAAKKEQEAAEKK 1253
Query: 425 IQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEI 484
E A+++ E E K + A + +ALK + KL E + K AI K +
Sbjct: 1254 KCAEAAKKEKEAEKKRKCEKA-----EKAAALKRQCAKLVIRAKEAALRKKCAIIAK-KA 1307
Query: 485 SNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEK 544
A E E A K++ A +KC +++ + A ++ EKE EK
Sbjct: 1308 KMAAEKKECEKLAKKAKEAIEWKKCAKLAKKKREAEKKKCAKLAKKEKEA-------AEK 1360
Query: 545 EKIVADSERKTAVDERKKAAAEARK 569
+K D + +KK E RK
Sbjct: 1361 KKRCKDLAKNKKKGHKKKGRNENRK 1385
>emb|CAA51876.1| mst101(2) [Drosophila hydei] gi|730072|sp|Q08696|MST2_DROHY
Axoneme-associated protein mst101(2)
Length = 1391
Score = 168 bits (426), Expect = 6e-40
Identities = 205/809 (25%), Positives = 369/809 (45%), Gaps = 57/809 (7%)
Query: 17 KCEELKKKCEQVVVGRNALRQAVKILEKGI-ENLESENKKLKKDIQE--EQAQRKVAIEG 73
K E+ KK C+++ + + K E E +E KK +K +E E A++K E
Sbjct: 359 KEEDEKKACKELAKKKKEADEKKKCEEAANKEKKAAEKKKCEKAAKERKEAAEKKKCEE- 417
Query: 74 KLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVK 133
AA + + +A + ++L ++I ++ A+ K C + K EK R + K
Sbjct: 418 --------AAKKEKEAAERKKCEELAKNI-KKAAEKKKCKEAAKKEKEAAERKKCEELAK 468
Query: 134 ILEKRIENLESENKKLK-KDIQE----EQAQRKIEIEGKLEKSNAFAALENEVSALKSEN 188
++K E + E K K++ E E+ +KI+ +K A E E + K
Sbjct: 469 KIKKAAEKKKCEETAKKGKEVAERKKCEELAKKIKKAEIKKKCKKLAKKEKETAEKKKCE 528
Query: 189 KKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALK----SENKKLKQDILD--EQA 242
K KK +E A++K + + A + E SA K +E KK ++ + E A
Sbjct: 529 KAAKKR--KEAAEKKKCEKAAKKRKEAAEKKKCEKSAKKRKEAAEKKKCEKAAKERKEAA 586
Query: 243 QGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEG 302
+ K C+ KK EK V R + K ++K +E KK K+ ++E + E G
Sbjct: 587 EKKKCEEAAKK-EKEVAERKKCEELAKKIKKA-----AEKKKCKEAAKKEKEAAEREKCG 640
Query: 303 KLEISNAFAALENEVSAL-KSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSA 361
+L AA + + L K E + +K E+ A+++ K + + A A E E +
Sbjct: 641 ELAKKIKKAAEKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCAEA-AKKEKEAAE 699
Query: 362 LKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKL 421
K + K++ +E A+ K C++L KK +K E + + A K L+ NKK
Sbjct: 700 KKKCEEAAKKE--KEAAERKKCEELAKKIKKAAEKKKCKKLAKKKKAGEKNKLKKGNKKG 757
Query: 422 KKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEK 481
KK ++E++ R++ + E A + E A + + + +E+A+ K +
Sbjct: 758 KKALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTA 817
Query: 482 LEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKEL 541
+ A + E +A K + A ++KC +++ E K ++ +K+
Sbjct: 818 KKRKEAAEKKKCEKAAKKRKEEAEKKKCEKTAKKRKETAEKKKC------EKAAKKRKQA 871
Query: 542 VEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANC-CSKCDELKKK 600
EK+K ++++ E+KK A A+K E A+K E+A E KC+EL KK
Sbjct: 872 AEKKKCEKAAKKRKEAAEKKKCAEAAKKEKELAEKKKCEEAAKKEKEVAERKKCEELAKK 931
Query: 601 CEKVAVGRNALRQAVKILEKGIEN-LESENKKLKKENEVSALKSEISALQQKCGAGAREG 659
+K A + + A K + G +N L+ + K KK+ + KS+ +A ++KC A++
Sbjct: 932 IKKAAEKKKCKKLAKKEKKAGEKNKLKKKAGKGKKKCKKLGKKSKRAAEKKKCAEAAKKE 991
Query: 660 NGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKK 719
+A +E + +KE E+++ +++ E+K A+KL EA +K
Sbjct: 992 K------EAATKKKCEERAKKQKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEK 1045
Query: 720 IAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAES 779
E + +L++ +KQ ER KL E ++ K+ +R A+K+K EK E
Sbjct: 1046 KQCEERAK----KLKEAAEQKQCEERAKKLK-EAAEKKQCEER--AKKEKEAAEKKQCEE 1098
Query: 780 KIKKAQERSESELDKKTADMEKQQAEEQK 808
+ KK +E +E + ++ A EK+ AE+++
Sbjct: 1099 RAKKLKEAAEKKQCEERAKKEKEAAEKKR 1127
Score = 158 bits (400), Expect = 6e-37
Identities = 206/825 (24%), Positives = 355/825 (42%), Gaps = 79/825 (9%)
Query: 17 KCEELKKKCEQVVVGRNALRQAVKILEKGIENLESEN--KKLKKDIQEEQA---QRKVAI 71
KCEE KK E+ V R + K ++K E + + KK K+ + E+ +K+
Sbjct: 590 KCEEAAKK-EKEVAERKKCEELAKKIKKAAEKKKCKEAAKKEKEAAEREKCGELAKKIKK 648
Query: 72 EGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQA 131
+ + A E E + K K+ +E A+ K C + K EK + +A
Sbjct: 649 AAEKKKCKKLAKKEKETAEKKKCEKAAKKR--KEAAEKKKCAEAAKKEKEAAEKKKCEEA 706
Query: 132 VKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKL 191
K ++ E + E +L K I++ ++K + K +K+ E + LK NKK
Sbjct: 707 AKKEKEAAERKKCE--ELAKKIKKAAEKKKCKKLAKKKKAG-------EKNKLKKGNKKG 757
Query: 192 KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLK 251
KK + E++ R++A + E A + E A + + + E+A+ K C++
Sbjct: 758 KKALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTA 817
Query: 252 KKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFA 311
KK ++ E + + A K E E+E KK +K A+++ E K + A
Sbjct: 818 KKRKEAAEKKKCEKAAKKRKE------EAEKKKCEKT-----AKKRKETAEKKKCEKAAK 866
Query: 312 ALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQ 371
+ K E K+ +E A++K E A E E++ K + K+
Sbjct: 867 KRKQAAEKKKCEKAAKKR---KEAAEKKKCAEA--------AKKEKELAEKKKCEEAAKK 915
Query: 372 DILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQ 431
+ +E A+ K C++L KK +K E + + A K E E KLKK + + +
Sbjct: 916 E--KEVAERKKCEELAKKIKKAAEKKKCKKLAKK------EKKAGEKNKLKK--KAGKGK 965
Query: 432 RKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAAL 491
+K + GK S A + A K E K EE+A+ + EK + L
Sbjct: 966 KKCKKLGKK--SKRAAEKKKCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAKKL 1023
Query: 492 ENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLK-KELVEKEKIVAD 550
+ + E A + K A ++ + LK + E K KE EK++
Sbjct: 1024 KEAAEQKQCEERAKKLKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCEER 1083
Query: 551 SERKTAVDERKKAAAEARKLLEAA-KKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRN 609
++++ E+K+ A+KL EAA KK E+A + A +C+E K+ ++ A +
Sbjct: 1084 AKKEKEAAEKKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKRCEEAAKREKEAAEKKK 1143
Query: 610 ALRQAVKILE-----KGIENLESENKKLKKENEVSALKSEISALQ-QKCGAGAREGNGDV 663
A K E K E + E + +K+ A K E A Q +KC A++
Sbjct: 1144 CAEAAKKEKEATEKQKCAEAAKKEKEAAEKKKCAEAAKREKEAAQKKKCADLAKKEQEPA 1203
Query: 664 EVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEA--PKKIA 721
E+ K +E + +KE E+++ ++++ E+K A A+K EA KK A
Sbjct: 1204 EMKKC------EEAAKKEKEAAEKQKCAKAAKKEKEAAEKKKCAEAAKKEQEAAEKKKCA 1257
Query: 722 AEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFE----AEKKKLLVEKINA 777
+K+ + R+ ++ K + A + + KEA R + A+K K+ EK
Sbjct: 1258 EAAKKEKEAEKKRKCEKAEKAAALKRQCAKLVIRAKEAALRKKCAIIAKKAKMAAEKKEC 1317
Query: 778 ESKIKKAQERSE----SELDKKTADMEKQQ----AEEQKKLAEDK 814
E KKA+E E ++L KK + EK++ A+++K+ AE K
Sbjct: 1318 EKLAKKAKEAIEWKKCAKLAKKKREAEKKKCAKLAKKEKEAAEKK 1362
Score = 155 bits (392), Expect = 5e-36
Identities = 210/851 (24%), Positives = 363/851 (41%), Gaps = 68/851 (7%)
Query: 17 KCEELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLE 76
KCEEL KK ++ + + + A K E + + K +K+ E++ K A + K
Sbjct: 494 KCEELAKKIKKAEIKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCEKAAKKRKEA 553
Query: 77 ISNTFAALENEVSALISENKKLKQDILE--EQAQGKICDQLKKCEKVVEGRNALRQAVKI 134
+ +E KK ++ E E A+ K C++ K EK V R + K
Sbjct: 554 AEKKKCEKSAKKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKK 613
Query: 135 LEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSAL-KSENKKLKK 193
++K +E KK K+ ++E+ + E G+L K AA + + L K E + +K
Sbjct: 614 IKKA-----AEKKKCKEAAKKEKEAAEREKCGELAKKIKKAAEKKKCKKLAKKEKETAEK 668
Query: 194 DILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKK 253
E+ A+++ K + + A A E E + K + K++ E A+ K C+ L KK
Sbjct: 669 KKCEKAAKKRKEAAEKKKCAEA-AKKEKEAAEKKKCEEAAKKE--KEAAERKKCEELAKK 725
Query: 254 CEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAAL 313
+K E + + A K L+ NKK KK ++E+ R++ + E A
Sbjct: 726 IKKAAEKKKCKKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKKAAEKKKCKEAA 785
Query: 314 ENEVSAL---------KSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKS 364
+ E A K ++ +K E+ A+++ K + A + E K
Sbjct: 786 KKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAKKRKEEAEKKKC 845
Query: 365 ENKKLKQDILEEQAQGKFCDQL---------KKKCEKVVEGRNALRQAVKILEKGIENLE 415
E K+ +E A+ K C++ KKKCEK + R + K E + E
Sbjct: 846 EKTAKKR---KETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKE 902
Query: 416 SENKKL-------KKDIQE----EQAQRKIEIEGKLEISNAFAALEN---EVSALKSEST 461
KK +K++ E E+ +KI+ + + A E E + LK ++
Sbjct: 903 LAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKKLAKKEKKAGEKNKLKKKAG 962
Query: 462 KLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVE 521
K KK + + K A E+K + + A + + K E A +QK A ++ +
Sbjct: 963 KGKKKCKKLGKKSKRAAEKK-KCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAK 1021
Query: 522 VLKAGISDTEKEVNTLK-KELVEKEKIVADSERKTAVDERKKAAAEARKLLEAA-KKIAP 579
LK + E K KE EK++ +++ E+K+ A+KL EAA KK
Sbjct: 1022 KLKEAAEQKQCEERAKKLKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCE 1081
Query: 580 EKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGI-----ENLESENKKLKK 634
E+A + A +C+E KK ++ A + +A K E E + E + +K
Sbjct: 1082 ERAKKEKEAAEKKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKRCEEAAKREKEAAEK 1141
Query: 635 ENEVSALKSEISALQ-QKCGAGAREGNGDVEVLK-AGISDTKKEVNRLKK--EHVEEERI 690
+ A K E A + QKC A++ E K A + +KE + KK + ++E+
Sbjct: 1142 KKCAEAAKKEKEATEKQKCAEAAKKEKEAAEKKKCAEAAKREKEAAQKKKCADLAKKEQE 1201
Query: 691 VADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLA 750
A+ ++ +++ AAE +K +A KK EK+ + + ++Q K K A
Sbjct: 1202 PAEMKKCEEAAKKEKEAAEKQKCAKAAKKEKEAAEKK----KCAEAAKKEQEAAEKKKCA 1257
Query: 751 FELSKTKEATKRFEAEK-KKLLVEKINAESKIKKAQE---RSESELDKKTADM--EKQQA 804
K KEA K+ + EK +K K + +A+E R + + K A M EK++
Sbjct: 1258 EAAKKEKEAEKKRKCEKAEKAAALKRQCAKLVIRAKEAALRKKCAIIAKKAKMAAEKKEC 1317
Query: 805 EEQKKLAEDKL 815
E+ K A++ +
Sbjct: 1318 EKLAKKAKEAI 1328
Score = 148 bits (373), Expect = 8e-34
Identities = 214/799 (26%), Positives = 357/799 (43%), Gaps = 97/799 (12%)
Query: 47 ENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISEN--KKLKQDI-- 102
+N E + K+L+++I +EQA+ + I G ++ EV E KK +D+
Sbjct: 291 KNDEKKEKELEREILKEQAEEEAKIRGVVK----------EVKKKCKEKALKKKCKDLGR 340
Query: 103 -LEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRK 161
++E+A+ K C L K +K + + A ++ K + E++ KK + E+A K
Sbjct: 341 KMKEEAEKKKCAALAKKQKEEDEKKACKELAK------KKKEADEKK-----KCEEAANK 389
Query: 162 IEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALEN 221
+ + +K A E + K + KK+ +E A+RK E I A
Sbjct: 390 EKKAAEKKKCEKAAKERKEAAEKKKCEEAAKKE--KEAAERKKCEELAKNIKKA------ 441
Query: 222 EVSALKSENKKLKQDILDEQ--AQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLE 279
+E KK K+ E+ A+ K C+ L KK +K E + A +KG E E
Sbjct: 442 ------AEKKKCKEAAKKEKEAAERKKCEELAKKIKKAAEKKKCEETA----KKGKEVAE 491
Query: 280 SEN-KKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQR 338
+ ++L K I +K EI+ K + A E E + K K KK +E A++
Sbjct: 492 RKKCEELAKKI------KKAEIKKKCK---KLAKKEKETAEKKKCEKAAKKR--KEAAEK 540
Query: 339 KVAMEGKLEISNAFAALENEVSALK----SENKKLKQDILE--EQAQGKFCDQLKKKCEK 392
K + + A + E SA K +E KK ++ E E A+ K C++ KK EK
Sbjct: 541 KKCEKAAKKRKEAAEKKKCEKSAKKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKK-EK 599
Query: 393 VVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENE 452
V R + K ++K +E KK K+ ++E+ + E G+L AA + +
Sbjct: 600 EVAERKKCEELAKKIKKA-----AEKKKCKEAAKKEKEAAEREKCGELAKKIKKAAEKKK 654
Query: 453 VSAL-KSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGA 511
L K E +K E+ A+ + EK + + A + K E AA ++K A
Sbjct: 655 CKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKEAAEKKKCEEAAKKEKEAA 714
Query: 512 GSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSER-KTAVDERKKA------- 563
++ + +K + + KK+ EK K+ +++ K A+ E+KK
Sbjct: 715 ERKKCEELAKKIKKAAEKKKCKKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKK 774
Query: 564 AAEARKLLEAAKKI--APEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKG 621
AAE +K EAAKK A EK + A K + KKKCEK A R + K EK
Sbjct: 775 AAEKKKCKEAAKKEKEAAEKKKCEKTAKK-RKEEAEKKKCEKTAKKRKEAAEKKKC-EKA 832
Query: 622 IENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLK 681
+ + E +K K+ E +A K + +A ++KC A++ E K + K++ K
Sbjct: 833 AKKRKEEAEK--KKCEKTAKKRKETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEK 890
Query: 682 K---EHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHL 738
K E ++E+ +A+ ++ +++ AE +K E KKI EK+ K ++
Sbjct: 891 KKCAEAAKKEKELAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKKLAKK--- 947
Query: 739 EKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQ----ERSESELDK 794
EK+ E K KL + K K+ K+ + K+ +K AE+ K+ + ++ E K
Sbjct: 948 EKKAGE-KNKLKKKAGKGKKKCKKLGKKSKRAAEKKKCAEAAKKEKEAATKKKCEERAKK 1006
Query: 795 KTADMEKQQAEEQ-KKLAE 812
+ EK+Q EE+ KKL E
Sbjct: 1007 QKEAAEKKQCEERAKKLKE 1025
Score = 135 bits (341), Expect = 4e-30
Identities = 197/735 (26%), Positives = 315/735 (42%), Gaps = 102/735 (13%)
Query: 113 DQLKKCEKVVEGR--NALRQAVK-----ILEKRIENLESENKKLKKDIQ-----EEQAQR 160
++ KK +K+V+ R L +K + E R E E K+L + + R
Sbjct: 205 NRAKKGKKLVKNRFTQKLEHCIKSEWADVCECRQNFTEDERKRLAASYKCMGTKIKSICR 264
Query: 161 KIEIEGKLEKSNAFAALENEVSALKSEN-----KKLKKDILEEQAQRKVAMEGKLEISNA 215
K I E + + E + K +N K+L+++IL+EQA+ + + G
Sbjct: 265 KRVIAEMCEAAGYVKSSEPKKKGKKKKNDEKKEKELEREILKEQAEEEAKIRG------- 317
Query: 216 FAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGI 275
+K KK K E+A K C L +K ++ E + A K E+
Sbjct: 318 ---------VVKEVKKKCK-----EKALKKKCKDLGRKMKEEAEKKKCAALAKKQKEEDE 363
Query: 276 ENLESENKKLKKDIQE----EHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDI 331
+ E K KK+ E E A K + + + A E + K + KK+
Sbjct: 364 KKACKELAKKKKEADEKKKCEEAANKEKKAAEKKKCEKAAKERKEAAEKKKCEEAAKKE- 422
Query: 332 LEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQ--AQGKFCDQLKKK 389
+E A+RK E I A +E KK K+ +E+ A+ K C++L KK
Sbjct: 423 -KEAAERKKCEELAKNIKKA------------AEKKKCKEAAKKEKEAAERKKCEELAKK 469
Query: 390 CEKVVEGRNALRQAVKILEKGIENLESEN-KKLKKDIQEEQAQRKIEIEGKLEISNAFAA 448
+K E + A +KG E E + ++L K I++ + ++K + K E A
Sbjct: 470 IKKAAEKKKCEETA----KKGKEVAERKKCEELAKKIKKAEIKKKCKKLAKKEKETA-EK 524
Query: 449 LENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQK 508
+ E +A K + KK + + K A E+K + E SA K + AA ++K
Sbjct: 525 KKCEKAAKKRKEAAEKKKCEKAAKKRKEAAEKK----------KCEKSAKKRKEAAEKKK 574
Query: 509 CGAGSREGNGDVEVLKAG-ISDTEKEVNTLKK---------ELVEKEKIVADSERKTAVD 558
C ++E E K + EKEV KK + EK+K ++++
Sbjct: 575 CEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKEAAKKEKEAA 634
Query: 559 ERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKIL 618
ER+K A+K+ +AA+K +K E K KKKCEK A R + K
Sbjct: 635 EREKCGELAKKIKKAAEKKKCKKLAKKE------KETAEKKKCEKAAKKRKEAAEKKKCA 688
Query: 619 EKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKK--- 675
E + E+ KK+ E +A K + +A ++KC A++ E K KK
Sbjct: 689 EAAKKEKEAAE---KKKCEEAAKKEKEAAERKKCEELAKKIKKAAEKKKCKKLAKKKKAG 745
Query: 676 EVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPK--KIAAEVEKQIAKVEL 733
E N+LKK + + ++ A E+K + K AAE +K EA K K AAE +K +
Sbjct: 746 EKNKLKKGNKKGKK--ALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAAEKKKCEKTAKK 803
Query: 734 RQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELD 793
R+ EK+ E+ K E ++ K+ K A+K+K EK E KK +E +E +
Sbjct: 804 RKEEAEKKKCEKTAKKRKEAAEKKKCEK--AAKKRKEEAEKKKCEKTAKKRKETAEKKKC 861
Query: 794 KKTADMEKQQAEEQK 808
+K A KQ AE++K
Sbjct: 862 EKAAKKRKQAAEKKK 876
Score = 124 bits (312), Expect = 1e-26
Identities = 195/797 (24%), Positives = 349/797 (43%), Gaps = 88/797 (11%)
Query: 53 NKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQG--K 110
+KK +K +EEQA+ + L++ A E S +++ L Q +++ G K
Sbjct: 68 DKKKQKQKEEEQAKIREYKRECLKVQKRVLAEEIRCSG--EKDRILIQGMMKCLTDGMKK 125
Query: 111 ICDQLKKCEKVVEGRNALRQA-------VKILEKRIENLESENKKLKKDIQEEQAQRKIE 163
C ++ K + + + A++ A VK L K+ E +S+ K+ ++ E + +
Sbjct: 126 ACTKIAKAKLIADKELAVQCAALSKKDKVKALLKKCEREKSKEKECNQNSPAEGDKDRT- 184
Query: 164 IEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEV 223
K K+ + N+ + K K K +++ + +K+ K E ++ +N
Sbjct: 185 ---KKGKTKGKSGGGNKKRSTKENRAKKGKKLVKNRFTQKLEHCIKSEWADVCECRQNFT 241
Query: 224 SALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENK 283
+ E K+L + K R + E K K +N E + K
Sbjct: 242 ---EDERKRLAASYKCMGTKIKSICRKRVIAEMCEAAGYVKSSEPKKKGKKKKNDEKKEK 298
Query: 284 KLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAME 343
+L+++I +E A+ + +I G ++ + + ALK + K L + + EE ++K A
Sbjct: 299 ELEREILKEQAEEEAKIRGVVKEVKK----KCKEKALKKKCKDLGRKMKEEAEKKKCAAL 354
Query: 344 GKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQA 403
K + E+E A K KK K E + K C++ K +K E + +A
Sbjct: 355 AKKQKE------EDEKKACKELAKKKK-----EADEKKKCEEAANKEKKAAEKKKC-EKA 402
Query: 404 VKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKL 463
K ++ E + E K ++E A+RK E I A + + +A K +
Sbjct: 403 AKERKEAAEKKKCEEAAKK---EKEAAERKKCEELAKNIKKAAEKKKCKEAAKKEKEAAE 459
Query: 464 KKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVL 523
+K E +IK A E+K + E +A K + A ++KC +++ +
Sbjct: 460 RKKCEELAKKIKKAAEKK----------KCEETAKKGKEVAERKKCEELAKK------IK 503
Query: 524 KAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAV 583
KA I K++ +KE EK+K ++++ E+KK A+K EAA+K EK+
Sbjct: 504 KAEIKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCEKAAKKRKEAAEKKKCEKSA 563
Query: 584 -----IPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKL--KKEN 636
E C E K+ EK A ++ K E L + KK KK+
Sbjct: 564 KKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKC 623
Query: 637 EVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIV-ADSE 695
+ +A K + +A ++KCG A++ + KA K++ + +KE E+++ A +
Sbjct: 624 KEAAKKEKEAAEREKCGELAKK------IKKAAEKKKCKKLAKKEKETAEKKKCEKAAKK 677
Query: 696 RKTAVDERKNA--------AAEARKLLEAPKKI--AAEVEK--QIAKVELRQVHLEKQVN 743
RK A +++K A AAE +K EA KK AAE +K ++AK + +K
Sbjct: 678 RKEAAEKKKCAEAAKKEKEAAEKKKCEEAAKKEKEAAERKKCEELAKKIKKAAEKKKCKK 737
Query: 744 ERKMKLAFELSKTKEATKRFEA---EKKK---LLVEKINAESKIKKAQERSESELDKKTA 797
K K A E +K K+ K+ + EKKK L +K + K K+A ++ + +KK
Sbjct: 738 LAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAAEKKKC 797
Query: 798 DMEKQQAEEQKKLAEDK 814
+ + A+++K+ AE K
Sbjct: 798 E---KTAKKRKEEAEKK 811
Score = 91.7 bits (226), Expect = 9e-17
Identities = 141/565 (24%), Positives = 242/565 (41%), Gaps = 53/565 (9%)
Query: 22 KKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTF 81
KKKCE+ R + K + + E+ KK K + + ++++A + K E +
Sbjct: 858 KKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKK--KCAEAAKKEKELAEKKKCEEA--- 912
Query: 82 AALENEVSALISENKKLKQ--DILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRI 139
A E EV+ E KK ++ +++ A+ K C +L K EK +N L++ +K+
Sbjct: 913 AKKEKEVA----ERKKCEELAKKIKKAAEKKKCKKLAKKEKKAGEKNKLKKKAGKGKKKC 968
Query: 140 ENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQ 199
+ L ++K+ + + +A +K + +K A + E + K ++ KK L+E
Sbjct: 969 KKLGKKSKRAAEKKKCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAKK--LKEA 1026
Query: 200 AQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVE 259
A++K E ++ A + E A KKLK E A+ K C+ KK ++ E
Sbjct: 1027 AEQKQCEERAKKLKEAAEKKQCEERA-----KKLK-----EAAEQKQCEERAKKLKEAAE 1076
Query: 260 GRNALRQAVKILEKGIEN-LESENKKLKKDIQ----EEHAQRKVEIEGKLEISNAFAALE 314
+ +A K E + E KKLK+ + EE A+++ E K A A E
Sbjct: 1077 KKQCEERAKKEKEAAEKKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKRCEEA-AKRE 1135
Query: 315 NEVSALK--SENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQD 372
E + K +E K +K+ E+Q + A + K E + E ++ KK D
Sbjct: 1136 KEAAEKKKCAEAAKKEKEATEKQKCAEAAKKEK-EAAEKKKCAEAAKREKEAAQKKKCAD 1194
Query: 373 IL---EEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILE-----KGIENLESENKKLKKD 424
+ +E A+ K C++ KK ++ E + + A K E K E + E + +K
Sbjct: 1195 LAKKEQEPAEMKKCEEAAKKEKEAAEKQKCAKAAKKEKEAAEKKKCAEAAKKEQEAAEKK 1254
Query: 425 IQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEI 484
E A+++ E E K + A + +ALK + KL E + K AI K +
Sbjct: 1255 KCAEAAKKEKEAEKKRKCEKA-----EKAAALKRQCAKLVIRAKEAALRKKCAIIAK-KA 1308
Query: 485 SNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEK 544
A E E A K++ A +KC +++ + A ++ EKE EK
Sbjct: 1309 KMAAEKKECEKLAKKAKEAIEWKKCAKLAKKKREAEKKKCAKLAKKEKEA-------AEK 1361
Query: 545 EKIVADSERKTAVDERKKAAAEARK 569
+K D + +KK E RK
Sbjct: 1362 KKRCKDLAKNKKKGHKKKGRNENRK 1386
>ref|XP_653447.1| Viral A-type inclusion protein repeat, putative [Entamoeba
histolytica HM-1:IMSS] gi|56470397|gb|EAL48061.1| Viral
A-type inclusion protein repeat, putative [Entamoeba
histolytica HM-1:IMSS]
Length = 1813
Score = 167 bits (422), Expect = 2e-39
Identities = 217/923 (23%), Positives = 422/923 (45%), Gaps = 169/923 (18%)
Query: 17 KCEELKKKCEQVVVGRNALRQAVKILEKGIENLESE---NKKLKKDIQ---EEQAQRKVA 70
K ELK++ +++ ++ L + GI L E K+ K++IQ EE+ ++
Sbjct: 870 KENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEEKEKLER 929
Query: 71 IEGKL-EISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALR 129
IE +L EI LE E + I E L+Q++ E + KI ++L + ++ E N
Sbjct: 930 IETELKEIKEAKQELEEEKNKTIEEKTNLQQELNENK---KIVEELTQTKQEKEEINNEL 986
Query: 130 QAVKILEKRIEN----LESENKKLK----KDIQEEQAQRKI------EIEGKLEKSNAFA 175
++K +KRIE + +ENK++K K I+E+ + E++G+LE+S
Sbjct: 987 NSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKGRLEESKGER 1046
Query: 176 A--------LENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISN--AFAALENEVSA 225
+ +E++ +K +N+ +KK + EE R M+ E S +L N+++
Sbjct: 1047 IEIEKERDRVISELNDIKLQNEGMKKQV-EEAHNRMTEMQKSFEGSENEMINSLNNQITQ 1105
Query: 226 LKSENKKLKQDILDEQ-------------------AQGKFCDRLKKKCEKVVEGRNALRQ 266
L + K++ + ++ Q +Q K+ ++ ++ + V + RN + +
Sbjct: 1106 LNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYT-QINEEKDCVEQERNKINE 1164
Query: 267 AVKILEKGIENLESENKKLKKDIQEEHAQRKVEI-EGKLEISNAFAALENEVSALKSENK 325
K + + +E +NKK D+Q ++ +E+ + K E+++ L+ E + L+ + K
Sbjct: 1165 EYKTVNEELE----KNKKELNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVK 1220
Query: 326 KLKKD-----------------ILEEQAQRKVAMEGKLEISNAFAAL-------ENEVSA 361
K++++ + EE Q K + K EI+N ++ E E +
Sbjct: 1221 KMEEEKSKLITELSNGSDGVSKLNEELTQTK---QEKEEINNELNSIKEEKKRIEEEKNQ 1277
Query: 362 LKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKL 421
+ +ENK++K++ + + + K +L K+ EK EG N L+ + ++ ++ +E +N+++
Sbjct: 1278 IINENKEIKEEKEKIEEEKK---ELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEI 1334
Query: 422 KKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEK 481
D +E A+ K E E L+ E++ +K E +KL D+ + EE
Sbjct: 1335 ICDNNKEIAKFKEEQEN----------LQKELNQIKEEKSKLITDLSNGNDGLSKLNEEI 1384
Query: 482 LEISNAFAALENEVSALKSEIAALQQKCGAGSRE-----------------GNGDVEVLK 524
I+ + E+ +LK E +Q + ++E GN + L
Sbjct: 1385 ETINKEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGINQLN 1444
Query: 525 AGISD--------TEK------EVNTLKKELVE-KEKIVADSERKTAVDERKKAAAEAR- 568
++ TEK E+N LK E E + + E V+E A E R
Sbjct: 1445 EDLNQIKNDKEELTEKNVQLQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIKEERD 1504
Query: 569 KLLEAAKKIAPEKAVIPEPAN-----CCSKCDELKKKCEKVAVGRNALRQAVKILEKGIE 623
+L++ KKI EK + E N + ++ + E++ N L+Q +K L+ IE
Sbjct: 1505 ELVKQIKKIEEEKRKVEEELNFNGSEVNEQIAQINNEKEQLNQECNELKQNLKELQSKIE 1564
Query: 624 NLESENK--KLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLK 681
+E E + ++KK+ E+ L+ EI+ E + D++ LK +E+ R++
Sbjct: 1565 EIEQEKESNEIKKKEELQELQEEIT-----------EKDNDIKNLK-------EEIERIE 1606
Query: 682 KEHVEEERIVADSERKTA-VDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEK 740
KE E+E + T ++E KN E ++LLE KK EK+ E + ++
Sbjct: 1607 KELQEKEEDMEQMSNNTEELEELKNKLTETQRLLEEEKK-----EKESISNEFEET--KE 1659
Query: 741 QVNERKMKLAFELSKTKEATKRFEAEKKKLL--VEKINAESKIKKAQERSESELDKKTAD 798
QV ++ E++K E + E EK++L + K+ ++ + + Q + S+L + ++
Sbjct: 1660 QVLVELQRVNNEMNKMNEIKQEDENEKEELQEHINKLKSQIERENEQLKEVSKLKWELSE 1719
Query: 799 MEKQQAEEQKKLAEDKLLLLGDS 821
+ K + E K++ +K LL ++
Sbjct: 1720 L-KTENESMKQMIMNKKSLLDNT 1741
Score = 164 bits (416), Expect = 8e-39
Identities = 183/822 (22%), Positives = 378/822 (45%), Gaps = 111/822 (13%)
Query: 42 LEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQD 101
+E+ + L++EN++LKK + + K ++ ++E LENE LI +
Sbjct: 182 IEEENKRLQNENEELKKKCDAQDSLLKTKMKSEMEAKKKVEILENEKKDLIDKMAN---- 237
Query: 102 ILEEQAQGKICDQLKKCEKVVEGRN----ALRQAVKILEKRIENLESENKKLKKDIQEEQ 157
E K+ ++L + + E N +Q + + + L+++N + + ++ + +
Sbjct: 238 --ENDGMSKLNEELTQIKNEKESINNELIQTKQEKESINNELTQLKTDNDQKENELNQVR 295
Query: 158 AQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKL--EISN- 214
++ IE + NE+S LK E K+ K++ L+EQ ++ + KL E+SN
Sbjct: 296 HEKDEVIEKFNTSKEENEKIMNELSQLKQE-KEEKENELKEQVKKMEEEKSKLITELSNG 354
Query: 215 --AFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILE 272
+ L E++ K E +++ ++ + +K++ +++ E +N + K ++
Sbjct: 355 SDGISKLNEELTQTKQEKEEINNEL----------NSIKEEKKRIEEEKNQIINENKEIK 404
Query: 273 KGIENLESENKKLKKDIQEE---HAQRKVEIE------GKLEISNAFAALEN--EVSALK 321
+ E +E E K+L K+I++E + Q + EI ++E N +N E++ K
Sbjct: 405 EEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFK 464
Query: 322 SENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGK 381
E + L+K++ + + +++ K E+ + ENE++ LK E K+ I E+
Sbjct: 465 EEQENLQKELNQIKEEKQKTENEKNELVDVKTQKENELNKLKEE----KEQIFNEKT--- 517
Query: 382 FCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLE 441
++ ++VE +N L + + +++ +++++++N + +I + E K +
Sbjct: 518 ---TIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTKELEINKIN-------EEKNQ 567
Query: 442 ISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSE 501
+ N + ++ E ++ E ++K + +++ ++ EEK ++ + A L +++
Sbjct: 568 LQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEKAKLITDIANGNDG 627
Query: 502 IAALQQ---KCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVD 558
+ L + K + ++ +K + E N K+E+ +KE +E +
Sbjct: 628 LTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQKE-----NETIQLNE 682
Query: 559 ERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKIL 618
E+ E ++ E +KI EKAVI + K +E+ K E V N L Q +K
Sbjct: 683 EKSVLLNELNQIKEEKQKIEDEKAVIQQ-----EKENEITKLNEDKTVIENELNQ-IKTE 736
Query: 619 EKGIEN--LESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKK- 675
++ IEN +++++K K E+E S L +E+S GN + L ++ TK+
Sbjct: 737 KQEIENELNQTKDEKQKIEDEKSKLITELS-----------NGNDGISKLNEELTQTKQE 785
Query: 676 ------EVNRLKKE-------HVEEERIVADSERKTAVD-ERKNAAAEARKLLEAPKKIA 721
E+N++K E + ++E + D K + E+KN E KL E I+
Sbjct: 786 KENVLNELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKN--NEVSKLEEEKGNIS 843
Query: 722 AEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKI 781
E+ ++E ++ + E++ K ++ KE K+ E EK KL+ E N I
Sbjct: 844 NELSNTKQELEQKKQEIITITQEKEEK----ENELKEQVKKIEEEKSKLITELSNGSDGI 899
Query: 782 KK-----AQERSESELDKKTADMEKQQAE----EQKKLAEDK 814
K Q + E E +K + EK++ E E K++ E K
Sbjct: 900 SKLNEELTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAK 941
Score = 161 bits (407), Expect = 9e-38
Identities = 200/921 (21%), Positives = 418/921 (44%), Gaps = 148/921 (16%)
Query: 4 EKAVIPEPANCCSKCEELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEE 63
EKAVI + K E+ K E V N L Q +K ++ IEN ++ K K+ I++E
Sbjct: 704 EKAVIQQ-----EKENEITKLNEDKTVIENELNQ-IKTEKQEIENELNQTKDEKQKIEDE 757
Query: 64 QA------------------------QRKVAIEGKL-EISNTFAALENE----VSALISE 94
++ Q K + +L +I N FA+ + + + L E
Sbjct: 758 KSKLITELSNGNDGISKLNEELTQTKQEKENVLNELNQIKNEFASFKEQNTQKENELKDE 817
Query: 95 NKKLKQDILE--------EQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESEN 146
N K++Q++ + E+ +G I ++L ++ +E + +Q + + + E E+E
Sbjct: 818 NNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQELEQK---KQEIITITQEKEEKENEL 874
Query: 147 KKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAM 206
K+ K I+EE+++ E+ S+ + L E++ K E ++++K LEE+ ++ +
Sbjct: 875 KEQVKKIEEEKSKLITELSNG---SDGISKLNEELTQTKQEKEEIQK-ALEEEKEKLERI 930
Query: 207 EGKL-EISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALR 265
E +L EI A LE E + E L+Q++ + + + + K++ E++ N+++
Sbjct: 931 ETELKEIKEAKQELEEEKNKTIEEKTNLQQELNENKKIVEELTQTKQEKEEINNELNSIK 990
Query: 266 QAVKILEKGIENLESENKKLK----KDIQEEHAQRKV------EIEGKLE--------IS 307
+ K +E+ + +ENK++K K I+E+ + E++G+LE I
Sbjct: 991 EEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKGRLEESKGERIEIE 1050
Query: 308 NAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISN--AFAALENEVSALKSE 365
+ +E++ +K +N+ +KK + EE R M+ E S +L N+++ L +
Sbjct: 1051 KERDRVISELNDIKLQNEGMKKQV-EEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEK 1109
Query: 366 NKKLKQDILEEQAQ-----------GKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENL 414
K++ + ++ Q Q K + + K ++ E ++ + Q + + + +
Sbjct: 1110 EKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTV 1169
Query: 415 ESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILE-EQAQ 473
E +K KK++ + Q + EI LE++ L + ++ LK E T L++ + + E+ +
Sbjct: 1170 NEELEKNKKELNDLQTKYDNEI---LELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEK 1226
Query: 474 IKVAIE--------------------EKLEISNAFAALENEVSALKSE----------IA 503
K+ E EK EI+N +++ E ++ E I
Sbjct: 1227 SKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIK 1286
Query: 504 ALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLK---KELVEK-EKIVADSERKTAVDE 559
++K +E ++E K G + + E+NT++ KE+ EK ++I+ D+ ++ A
Sbjct: 1287 EEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIA--- 1343
Query: 560 RKKAAAEARKLLEAAKKIAPEKA-VIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKIL 618
K E L + +I EK+ +I + +N +L ++ E + + +R
Sbjct: 1344 --KFKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIR------ 1395
Query: 619 EKGIENLESENKKLK-----KENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDT 673
K +E+L+ EN K++ K E+S +K E ++K GN + L ++
Sbjct: 1396 -KELESLKEENNKIQDELEQKNQELSKVKEE----KEKLIHDLTNGNDGINQLNEDLNQI 1450
Query: 674 KKEVNRLKKEHVEEERIV-----ADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQI 728
K + L +++V+ + + + E + K + + + A K+ E+ KQI
Sbjct: 1451 KNDKEELTEKNVQLQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIKEERDELVKQI 1510
Query: 729 AKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERS 788
K+E + +E+++N ++ ++++ ++ E +L +SKI++ ++
Sbjct: 1511 KKIEEEKRKVEEELNFNGSEVNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQEK 1570
Query: 789 ESELDKKTADMEKQQAEEQKK 809
ES KK ++++ Q E +K
Sbjct: 1571 ESNEIKKKEELQELQEEITEK 1591
Score = 159 bits (403), Expect = 3e-37
Identities = 191/852 (22%), Positives = 408/852 (47%), Gaps = 98/852 (11%)
Query: 16 SKCEELKKKCEQVVVGRNALRQAVKILE----KGIENLESENKKLKKDIQEEQAQRKVAI 71
++ +LK++ E+ N L++ VK +E K I L + + + K + EE Q K
Sbjct: 317 NELSQLKQEKEEK---ENELKEQVKKMEEEKSKLITELSNGSDGISK-LNEELTQTK--- 369
Query: 72 EGKLEISNTFAAL-------ENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEG 124
+ K EI+N ++ E E + +I+ENK++K++ +E+ + + + LK+ EK EG
Sbjct: 370 QEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEE--KEKIEEEKKELLKEIEKEKEG 427
Query: 125 RNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSAL 184
N L+ + ++ R++ +E +N+++ D +E A+ K E E L+ E++ +
Sbjct: 428 NNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQEN----------LQKELNQI 477
Query: 185 KSENKKL---KKDILEEQAQRKVAM----EGKLEISNAFAALENEVSALKSENKKL--KQ 235
K E +K K ++++ + Q++ + E K +I N +EN ++ + E KL ++
Sbjct: 478 KEEKQKTENEKNELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEK 537
Query: 236 DILDEQAQGKFCDRLKKKCE--KVVEGRNALRQAVKILEKGIENLESENKKLK-KDIQEE 292
+ + ++ D K+ E K+ E +N L+ +++ EN++ E ++K + Q+E
Sbjct: 538 ESIKQELDSIKADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKE 597
Query: 293 HAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKL-EISNA 351
K++ E K ++ + A L +++ KL +++++ K + +L +I N
Sbjct: 598 EELNKIK-EEKQQVEDEKAKLITDIANGNDGLTKLN-EVIDKLKDEKENISNELNQIKNE 655
Query: 352 FAALENEVSALKSENKKLKQDILEEQAQGKFC----DQLKKKCEKVVEGRNALRQA---- 403
+ NE + K E K+ + + ++ + +Q+K++ +K+ + + ++Q
Sbjct: 656 RDNISNEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENE 715
Query: 404 -VKILEKG--IENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSES 460
K+ E IEN ++ K K++I+ E Q K E K +I + + L E+S
Sbjct: 716 ITKLNEDKTVIENELNQIKTEKQEIENELNQTKDE---KQKIEDEKSKLITELSNGNDGI 772
Query: 461 TKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDV 520
+KL +++ + + + + + E +I N FA+ + + + ++E+ K + N +V
Sbjct: 773 SKLNEELTQTKQEKENVLNELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEV 832
Query: 521 EVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPE 580
L+ + E++ K+EL +K++ + T E+++ E L E KKI E
Sbjct: 833 SKLEEEKGNISNELSNTKQELEQKKQEII-----TITQEKEEKENE---LKEQVKKIEEE 884
Query: 581 KA-VIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKK----- 634
K+ +I E +N +L ++ + + +++A++ ++ +E +E+E K++K+
Sbjct: 885 KSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAKQEL 944
Query: 635 ENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKE--HVEEERIVA 692
E E + E + LQQ E N + ++++ ++ TK+E + E ++EE+
Sbjct: 945 EEEKNKTIEEKTNLQQ-------ELNENKKIVEE-LTQTKQEKEEINNELNSIKEEKKRI 996
Query: 693 DSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFE 752
+ E+ ++E K E K +E + E+ +E + LE+ ER E
Sbjct: 997 EEEKNQIINENKEIKEENIKSIEEKTQ---EINSLTTSIEELKGRLEESKGER-----IE 1048
Query: 753 LSKTKEAT-------KRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAE 805
+ K ++ K KK + E N ++++K+ E SE+E+ + Q E
Sbjct: 1049 IEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNE 1108
Query: 806 EQKKLAEDKLLL 817
++K++ E + L
Sbjct: 1109 KEKQMNEQVMAL 1120
Score = 138 bits (348), Expect = 6e-31
Identities = 166/756 (21%), Positives = 335/756 (43%), Gaps = 121/756 (16%)
Query: 93 SENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKD 152
SE + +++ K D+ K +K + + + +KR+ L ++ +
Sbjct: 89 SETQSQTNELVSTPPHEKSGDEAKNEQKQSSSQTSESTEKETHKKRLSFLGRKSFSKRNS 148
Query: 153 IQ-------EEQAQRKIEIEGKLEKSNAF--AALENEVSALKSENKKLKKDILEEQAQRK 203
+ E A + E E+ N A +E E L++EN++LKK + + K
Sbjct: 149 TENTGHSSSEHSATSSLASETTAEEVNRSVNAQIEEENKRLQNENEELKKKCDAQDSLLK 208
Query: 204 VAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNA 263
M+ ++E LENE K+D++D+ A D + K E++ + +N
Sbjct: 209 TKMKSEMEAKKKVEILENE-----------KKDLIDKMANEN--DGMSKLNEELTQIKNE 255
Query: 264 LRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSE 323
K+ I E Q K E E ++ NE++ LK++
Sbjct: 256 ----------------------KESINNELIQTKQEKE----------SINNELTQLKTD 283
Query: 324 NKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFC 383
N + + ++ + + + K E+ F + E + +E +LKQ+ E++
Sbjct: 284 NDQKENELNQVRHE-------KDEVIEKFNTSKEENEKIMNELSQLKQEKEEKE------ 330
Query: 384 DQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEIS 443
++LK++ +K+ E ++ L + GI L E + K++ +E + E K I
Sbjct: 331 NELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNELNSIKEEKKRIE 390
Query: 444 NAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIA 503
+ NE +K E K++ EE+ ++ IE++ E +N L+NE++ +++ +
Sbjct: 391 EEKNQIINENKEIKEEKEKIE----EEKKELLKEIEKEKEGNN---QLQNEINTIQTRMK 443
Query: 504 ALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKA 563
+++K + N ++ K + +KE+N +K+ EK+K ++E+ VD + +
Sbjct: 444 EIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKE---EKQK--TENEKNELVDVKTQK 498
Query: 564 AAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIE 623
E KL E ++I EK I N ++ +N L + + +++ ++
Sbjct: 499 ENELNKLKEEKEQIFNEKTTIENSLN-------------QIVEEKNKLTEEKESIKQELD 545
Query: 624 NLESENKKLKKENEVSALKSEISALQQKCGAGAREGNG---DVEVLKAGISDTKKEVNRL 680
+++++N KE E++ + E + LQ +E ++ +K S ++E+N++
Sbjct: 546 SIKADNS--TKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKI 603
Query: 681 K--KEHVEEER------IVADSERKTAV--------DERKNAAAEARKLLEAPKKIAAEV 724
K K+ VE+E+ I ++ T + DE++N + E ++ I+ E
Sbjct: 604 KEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEF 663
Query: 725 EKQIAKVELRQVHLEK-QVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKK 783
K K E++Q E Q+NE K L EL++ KE ++ E EK + EK N +K+ +
Sbjct: 664 NK--TKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNE 721
Query: 784 AQERSESEL-----DKKTADMEKQQAEEQKKLAEDK 814
+ E+EL +K+ + E Q +++K+ ED+
Sbjct: 722 DKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDE 757
Score = 115 bits (287), Expect = 8e-24
Identities = 138/572 (24%), Positives = 243/572 (42%), Gaps = 115/572 (20%)
Query: 311 AALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLK 370
A +E E L++EN++LKK + + K M+ ++E LENE K
Sbjct: 180 AQIEEENKRLQNENEELKKKCDAQDSLLKTKMKSEMEAKKKVEILENE-----------K 228
Query: 371 QDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQA 430
+D++++ A D + K E++ + +N ++ I N + K+ K+ I E
Sbjct: 229 KDLIDKMANEN--DGMSKLNEELTQIKNE--------KESINNELIQTKQEKESINNELT 278
Query: 431 QRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKL-EISNAFA 489
Q K + + K N ++EV + S + + I+ E +Q+K EEK E+
Sbjct: 279 QLKTDNDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNELSQLKQEKEEKENELKEQVK 338
Query: 490 ALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVA 549
+E E S L +E++ NG GIS +E+ K+E KE+I
Sbjct: 339 KMEEEKSKLITELS-------------NGS-----DGISKLNEELTQTKQE---KEEI-- 375
Query: 550 DSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRN 609
++E + +E+K+ E +++ K+I EK I E EL K+ EK G N
Sbjct: 376 NNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKK------ELLKEIEKEKEGNN 429
Query: 610 ALRQAVKILEKGIENLESENKKLKKEN--EVSALKSEISALQQKCGAGAREGNGDVEVLK 667
L+ + ++ ++ +E +N+++ +N E++ K E LQ++ +E E K
Sbjct: 430 QLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQ-IKEEKQKTENEK 488
Query: 668 AGISDTK----KEVNRLK--KEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIA 721
+ D K E+N+LK KE + E+ ++ V+E+ E + + I
Sbjct: 489 NELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIK 548
Query: 722 AE--------------------------VEKQIAKVELRQVHLEKQVNERKMKLAFELSK 755
A+ EK+ + EL Q+ +EK E EL+K
Sbjct: 549 ADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEE------ELNK 602
Query: 756 TKEATKRFEAEKKKLLVEKINAES----------KIKKAQERSESELDK----------- 794
KE ++ E EK KL+ + N K+K +E +EL++
Sbjct: 603 IKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNE 662
Query: 795 --KTADMEKQQAEEQKKLAEDKLLLLGDSLQL 824
KT + KQ+ E +L E+K +LL + Q+
Sbjct: 663 FNKTKEEIKQKENETIQLNEEKSVLLNELNQI 694
Score = 99.4 bits (246), Expect = 4e-19
Identities = 125/578 (21%), Positives = 245/578 (41%), Gaps = 76/578 (13%)
Query: 273 KGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDIL 332
KG + SE + ++ K E K E + + + S K +KK +
Sbjct: 82 KGFLSRRSETQSQTNELVSTPPHEKSGDEAKNEQKQSSS--QTSESTEKETHKKRLSFLG 139
Query: 333 EEQAQRKVAMEGKLEISNAFAALENEVSALKSE--NKKLKQDILEEQAQ-GKFCDQLKKK 389
+ ++ + E S+ +A + S +E N+ + I EE + ++LKKK
Sbjct: 140 RKSFSKRNSTENTGHSSSEHSATSSLASETTAEEVNRSVNAQIEEENKRLQNENEELKKK 199
Query: 390 CEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAAL 449
C+ ++ +K +E LE+E KKD+ ++ A ++ + L
Sbjct: 200 CDAQDSLLKTKMKSEMEAKKKVEILENE----KKDLIDKMANE----------NDGMSKL 245
Query: 450 ENEVSALKSES---------------------TKLKKDILEEQAQIKVAIEEKLEISNAF 488
E++ +K+E T+LK D +++ ++ EK E+ F
Sbjct: 246 NEELTQIKNEKESINNELIQTKQEKESINNELTQLKTDNDQKENELNQVRHEKDEVIEKF 305
Query: 489 AALENEVSALKSEIAALQQKCGAGSREGNGDVEVLK-------AGISDTEKEVNTLKKEL 541
+ E + +E++ L+Q+ E V+ ++ +S+ ++ L +EL
Sbjct: 306 NTSKEENEKIMNELSQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEEL 365
Query: 542 VE--KEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKK 599
+ +EK ++E + +E+K+ E +++ K+I EK I E EL K
Sbjct: 366 TQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKK------ELLK 419
Query: 600 KCEKVAVGRNALRQAVKILEKGIENLESENKKLKKEN--EVSALKSEISALQQKCGAGAR 657
+ EK G N L+ + ++ ++ +E +N+++ +N E++ K E LQ++ +
Sbjct: 420 EIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQ-IK 478
Query: 658 EGNGDVEVLKAGISDTK-KEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEA 716
E E K + D K ++ N L K E+E+I +E+ T + E KL E
Sbjct: 479 EEKQKTENEKNELVDVKTQKENELNKLKEEKEQIF--NEKTTIENSLNQIVEEKNKLTEE 536
Query: 717 PKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKIN 776
+ I E++ A +++ + K +NE K +L + ++ + + E ++ +EK
Sbjct: 537 KESIKQELDSIKADNSTKELEINK-INEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQ 595
Query: 777 AESKIKKAQERSESELDKKTADMEKQQAEEQK-KLAED 813
E ++ K +E EKQQ E++K KL D
Sbjct: 596 KEEELNKIKE-------------EKQQVEDEKAKLITD 620
Score = 93.2 bits (230), Expect = 3e-17
Identities = 93/425 (21%), Positives = 197/425 (45%), Gaps = 29/425 (6%)
Query: 16 SKCEELKKKCEQVVVGRNA----LRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAI 71
++ +E+++K ++++ N ++ + L+K + ++ E KL D+
Sbjct: 1322 TRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSKLN 1381
Query: 72 EGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVV-------EG 124
E I+ + E+ +L EN K++ ++ EQ ++ ++ EK++ +G
Sbjct: 1382 EEIETINKEKEGIRKELESLKEENNKIQDEL--EQKNQELSKVKEEKEKLIHDLTNGNDG 1439
Query: 125 RNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLE-KSNAFAALENEVSA 183
N L + + ++ E L +N +L+ +I + +++ + E+ L + + EV+A
Sbjct: 1440 INQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENE-ELSNNLSFEKEGLKQVNEEVNA 1498
Query: 184 LKSENKKLKKDILE-EQAQRKVAMEGKL---EISNAFAALENEVSALKSENKKLKQDILD 239
+K E +L K I + E+ +RKV E E++ A + NE L E +LKQ++ +
Sbjct: 1499 IKEERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQIAQINNEKEQLNQECNELKQNLKE 1558
Query: 240 EQAQGKFCDRLKKKCE-KVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKV 298
Q++ + ++ K+ E K E L++ + + I+NL+ E ++++K++QE+ +
Sbjct: 1559 LQSKIEEIEQEKESNEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQEKEEDMEQ 1618
Query: 299 EIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLE-ISNAFAAL-- 355
E+ L E L E KK K+ I E + K + +L+ ++N +
Sbjct: 1619 MSNNTEELEELKNKL-TETQRLLEEEKKEKESISNEFEETKEQVLVELQRVNNEMNKMNE 1677
Query: 356 -----ENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKG 410
ENE L+ KLK I E Q K +LK + ++ +++Q + +
Sbjct: 1678 IKQEDENEKEELQEHINKLKSQIERENEQLKEVSKLKWELSELKTENESMKQMIMNKKSL 1737
Query: 411 IENLE 415
++N +
Sbjct: 1738 LDNTD 1742
>gb|AAX79229.1| hypothetical protein, conserved [Trypanosoma brucei]
Length = 1692
Score = 158 bits (399), Expect = 8e-37
Identities = 208/877 (23%), Positives = 397/877 (44%), Gaps = 101/877 (11%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEIS 78
E +++C+ ++ ++ L + + + E LE+E ++L+ ++++ + + +++ +G E++
Sbjct: 704 ERQREQCQNLLNAQDDLLAELSGVSEEKEKLEAECERLEAELRQMEEKSRLSEQGLSEMT 763
Query: 79 NTFAALENEVSALISENKKLKQDI-----LEEQAQG-------KICDQLKKCEKVVEGRN 126
+ E+ L+ ++L + + E+ AQ +I D ++ E ++
Sbjct: 764 QRLEEKQAEIEGLLENLEQLDEQLEALRAAEKSAQAHIEARDREISDLQQRLEGEIDDHI 823
Query: 127 ALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKS 186
++ L K NLE ++ ++Q + K + ++ +LE + + +
Sbjct: 824 KTTALLEELRKHYNNLE--------ELFDKQEAELMAYREKRQNAHKVRSLEPTLRPIGT 875
Query: 187 ENKKLKKDILEEQAQRKVAMEGKLEI-------SNAFAA----LENEVSALKSENK---- 231
+ K ++ + ++ + + L+ SN F L ++ E +
Sbjct: 876 QTKPFQEMVSADEISSEPLLSVTLDEYNDHMHRSNQFQQENDLLRQQLQQANDERENLHD 935
Query: 232 KLKQDILDEQAQGKFCDRLKKKCEKVVEGRNAL-----RQAVKILEKGIEN--LESENKK 284
+L+Q + + Q+ + + ++ E+ R+ + R A +I K EN L EN K
Sbjct: 936 RLEQLMAENQSLSEQLHNMHEELEREERDRSGVTLQNERLAEEIQRKTAENEQLVLENNK 995
Query: 285 LKKDIQE---------EHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQ 335
+ DI+ E + K KL A ENE A + E K + + L E+
Sbjct: 996 SRSDIRNLNVQVQRLMEELELKAAENEKLAEELELKAAENEKLAEELELKVAENEKLAEE 1055
Query: 336 AQRKVAMEGKLEISNAFAALENEVSALK-----SENKKLKQDILEEQAQG-KFCDQLKKK 389
+ KVA KL A ENE A + +EN+KL +++ + A+ K ++L+ K
Sbjct: 1056 LELKVAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELK 1115
Query: 390 C---EKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAF 446
EK+ E + L + +E +EN+KL ++++ + A+ + ++ +LE+ A
Sbjct: 1116 AAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENE-KLAEELELKVA- 1173
Query: 447 AALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQ 506
ENE A + E + + L E+ ++KVA EKL A ENE A + E+ A +
Sbjct: 1174 ---ENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKAAE 1230
Query: 507 QKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDER-----K 561
+ A E L+ ++ EK L+ + E EK+ + E K A +E+ +
Sbjct: 1231 NEKLA---------EELELKAAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELE 1281
Query: 562 KAAAEARKLLEAAK-KIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKIL-- 618
AAE KL E + K+A + + E ++ ++L ++ E L + +++
Sbjct: 1282 LKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELKAA 1341
Query: 619 --EKGIENLE---SENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDT 673
EK E LE +EN+KL +E E+ A ++E A + + A E + LKA ++
Sbjct: 1342 ENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKA--AEN 1399
Query: 674 KKEVNRLKKEHVEEERIVADSERKTAVDER-----KNAAAEARKLLEAPKKIAAEVEKQI 728
+K L+ + E E++ + E K A +E+ + AE KL E + AAE EK
Sbjct: 1400 EKLAEELELKAAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLA 1459
Query: 729 AKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQ-ER 787
++EL+ EK E ++K A E K E E E K EK+ E ++K A+ E+
Sbjct: 1460 EELELKVAENEKLAEELELKAA-ENEKLAE-----ELELKAAENEKLAEELELKAAENEK 1513
Query: 788 SESELDKKTADMEKQQAEEQKKLAEDKLLLLGDSLQL 824
EL+ K A+ ++ E ++L+E +LL S +L
Sbjct: 1514 LAEELELKVAENKRLAEEVTQRLSEKELLAEDTSARL 1550
Score = 157 bits (398), Expect = 1e-36
Identities = 200/850 (23%), Positives = 380/850 (44%), Gaps = 95/850 (11%)
Query: 7 VIPEPANCCSKCEELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQ 66
++ E + + E+L+ +CE++ + + ++ E+G+ ++ + ++E+QA+
Sbjct: 720 LLAELSGVSEEKEKLEAECERLEAELRQMEEKSRLSEQGL-------SEMTQRLEEKQAE 772
Query: 67 RKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRN 126
IEG LE L+ ++ AL + K + I E +I D ++ E ++
Sbjct: 773 ----IEGLLE---NLEQLDEQLEALRAAEKSAQAHI--EARDREISDLQQRLEGEIDDHI 823
Query: 127 ALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKS 186
++ L K NLE ++ ++Q + K + ++ +LE + + +
Sbjct: 824 KTTALLEELRKHYNNLE--------ELFDKQEAELMAYREKRQNAHKVRSLEPTLRPIGT 875
Query: 187 ENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKF 246
+ K ++ + ++ + + L+ N N+ + EN L+Q + +QA +
Sbjct: 876 QTKPFQEMVSADEISSEPLLSVTLDEYNDHMHRSNQ---FQQENDLLRQQL--QQANDE- 929
Query: 247 CDRLKKKCEKVVEGRNALRQAVKILEKGIENLES-------ENKKLKKDIQEEHAQRKVE 299
+ L + E+++ +L + + + + +E E +N++L ++IQ + A+
Sbjct: 930 RENLHDRLEQLMAENQSLSEQLHNMHEELEREERDRSGVTLQNERLAEEIQRKTAE---- 985
Query: 300 IEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEV 359
N LEN S N ++ L E+ + K A KL A ENE
Sbjct: 986 --------NEQLVLENNKSRSDIRNLNVQVQRLMEELELKAAENEKLAEELELKAAENEK 1037
Query: 360 SALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENK 419
A + E K + + L E+ + K + EK+ E + L + +E +EN+
Sbjct: 1038 LAEELELKVAENEKLAEELELKVAEN-----EKLAEELELKAAENEKLAEELELKAAENE 1092
Query: 420 KLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIE 479
KL ++++ + A+ + ++ +LE+ A ENE A + E + + L E+ ++K A
Sbjct: 1093 KLAEELELKAAENE-KLAEELELK----AAENEKLAEELELKAAENEKLAEELELKAAEN 1147
Query: 480 EKLEISNAFAALENEVSALKSEIAA-----LQQKCGAGSREGNGDVEVLKAGISDTEKEV 534
EKL A ENE A + E+ L ++ + E E L+ +++ EK
Sbjct: 1148 EKLAEELELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKVAENEKLA 1207
Query: 535 NTLKKELVEKEKIVADSERKTAVDER-----KKAAAEARKLLEAAKKIAPEKAVIPEPAN 589
L+ + E EK+ + E K A +E+ + AAE KL E + A E + E
Sbjct: 1208 EELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELE 1267
Query: 590 C-CSKCDELKKKCEKVAVGRNALRQAVKIL----EKGIENLE---SENKKLKKENEVSAL 641
++ ++L ++ E A L + +++ EK E LE +EN+KL +E E+
Sbjct: 1268 LKVAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKVA 1327
Query: 642 KSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVD 701
++E L ++ A E E L+ +++ +K L+ + E E++ + E K A +
Sbjct: 1328 ENE--KLAEELELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKAAEN 1385
Query: 702 ER-----KNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKT 756
E+ + AAE KL E + AAE EK ++EL+ EK E ++K+A E K
Sbjct: 1386 EKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKVA-ENEKL 1444
Query: 757 KEATKRFEAEKKKLLV---------EKINAESKIKKAQ-ERSESELDKKTADMEKQQAEE 806
E + AE +KL EK+ E ++K A+ E+ EL+ K A+ EK E
Sbjct: 1445 AEELELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKAAENEKLAEEL 1504
Query: 807 QKKLAEDKLL 816
+ K AE++ L
Sbjct: 1505 ELKAAENEKL 1514
Score = 152 bits (383), Expect = 6e-35
Identities = 198/790 (25%), Positives = 355/790 (44%), Gaps = 86/790 (10%)
Query: 6 AVIPEPANCCSKCEELKKKCEQVVVGRNALRQ---AVKILEKGIENLESENKKLKKDIQE 62
A++ E + EEL K E ++ RQ V+ LE + + ++ K ++ +
Sbjct: 827 ALLEELRKHYNNLEELFDKQEAELMAYREKRQNAHKVRSLEPTLRPIGTQTKPFQEMVSA 886
Query: 63 EQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVV 122
++ + + L+ N N+ EN L+Q + +QA + + + E+++
Sbjct: 887 DEISSEPLLSVTLDEYNDHMHRSNQFQ---QENDLLRQQL--QQANDERENLHDRLEQLM 941
Query: 123 EGRNALRQAVKILEKRIENLESE-------NKKLKKDIQEEQAQRKIEIEGKLEKSNAFA 175
+L + + + + +E E + N++L ++IQ + A+ N
Sbjct: 942 AENQSLSEQLHNMHEELEREERDRSGVTLQNERLAEEIQRKTAE------------NEQL 989
Query: 176 ALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQ 235
LEN S N ++ L E+ + K A KL A ENE A + E K +
Sbjct: 990 VLENNKSRSDIRNLNVQVQRLMEELELKAAENEKLAEELELKAAENEKLAEELELKVAEN 1049
Query: 236 DILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQ 295
+ L E+ + K + EK+ E + L + +E +EN+KL ++++ + A+
Sbjct: 1050 EKLAEELELKVAEN-----EKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAE 1104
Query: 296 RKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAAL 355
+ ++ +LE+ A ENE A + E K + + L E+ + K A KL A
Sbjct: 1105 NE-KLAEELELK----AAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAA 1159
Query: 356 ENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLE 415
ENE A + E K + + L E+ + K + EK+ E L V EK E LE
Sbjct: 1160 ENEKLAEELELKVAENEKLAEELELKAAEN-----EKLAE---ELELKVAENEKLAEELE 1211
Query: 416 ---SENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQA 472
+EN+KL ++++ + A+ + ++ +LE+ A ENE A + E + + L E+
Sbjct: 1212 LKAAENEKLAEELELKAAENE-KLAEELELK----AAENEKLAEELELKAAENEKLAEEL 1266
Query: 473 QIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEK 532
++KVA EKL A ENE A + E+ + + A E L+ ++ EK
Sbjct: 1267 ELKVAENEKLAEELELKAAENEKLAEELELKVAENEKLA---------EELELKAAENEK 1317
Query: 533 EVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCS 592
L+ ++ E EK+ + E K A E +K A E + +K+A E +
Sbjct: 1318 LAEELELKVAENEKLAEELELKAA--ENEKLAEELELKVAENEKLAEELEL--------- 1366
Query: 593 KCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKC 652
K E +K E++ + + K+ E+ +E +EN+KL +E E+ A ++E L ++
Sbjct: 1367 KAAENEKLAEELEL---KAAENEKLAEE-LELKAAENEKLAEELELKAAENE--KLAEEL 1420
Query: 653 GAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDER-----KNAA 707
A E E L+ +++ +K L+ + E E++ + E K A +E+ + A
Sbjct: 1421 ELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELKA 1480
Query: 708 AEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEK 767
AE KL E + AAE EK ++EL+ EK E ++K+A +E T+R +
Sbjct: 1481 AENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKVAENKRLAEEVTQRL--SE 1538
Query: 768 KKLLVEKINA 777
K+LL E +A
Sbjct: 1539 KELLAEDTSA 1548
Score = 145 bits (366), Expect = 5e-33
Identities = 207/891 (23%), Positives = 393/891 (43%), Gaps = 113/891 (12%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEIS 78
EE +++ + + +LRQ L I L +KL+ D+ + QA ++ + +
Sbjct: 602 EEFRRQTASTMREQESLRQRNGELHAEIGRLRDLVEKLR-DLADNQASELELLKLQKTQA 660
Query: 79 NTFAALENEVSALISENKK----LKQDILEEQAQGKICDQLKK--------CEKVVEGRN 126
N A N + + + + D L EQ + CDQ+++ C+ ++ ++
Sbjct: 661 NQIRAQRNLSTFRGDDTAEPVYCVTLDELREQTEH--CDQVERELERQREQCQNLLNAQD 718
Query: 127 ALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKS 186
L + + + E LE+E ++L+ ++++ + + ++ +G E + + E+ L
Sbjct: 719 DLLAELSGVSEEKEKLEAECERLEAELRQMEEKSRLSEQGLSEMTQRLEEKQAEIEGLLE 778
Query: 187 ENKKLKKDI-----LEEQAQRKVAMEGKLEISNAFAALENEV------SALKSENKK--- 232
++L + + E+ AQ + + EIS+ LE E+ +AL E +K
Sbjct: 779 NLEQLDEQLEALRAAEKSAQAHIEARDR-EISDLQQRLEGEIDDHIKTTALLEELRKHYN 837
Query: 233 LKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENL-------------- 278
+++ D+Q R K++ V + + K + +
Sbjct: 838 NLEELFDKQEAELMAYREKRQNAHKVRSLEPTLRPIGTQTKPFQEMVSADEISSEPLLSV 897
Query: 279 ---------------ESENKKLKKDIQEEHAQRKVEIEGKL-----EISNAFAALENEVS 318
+ EN L++ +Q+ + +R+ + +L E + L N
Sbjct: 898 TLDEYNDHMHRSNQFQQENDLLRQQLQQANDERE-NLHDRLEQLMAENQSLSEQLHNMHE 956
Query: 319 ALKSENK-----KLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDI 373
L+ E + L+ + L E+ QRK A +L + N + +++ L + ++L +++
Sbjct: 957 ELEREERDRSGVTLQNERLAEEIQRKTAENEQLVLENNKS--RSDIRNLNVQVQRLMEEL 1014
Query: 374 -LEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLE---SENKKLKKDIQEEQ 429
L+ K ++L+ K + + L V EK E LE +EN+KL ++++ +
Sbjct: 1015 ELKAAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELKVAENEKLAEELELKA 1074
Query: 430 AQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFA 489
A+ + ++ +LE+ A ENE A + E + + L E+ ++K A EKL
Sbjct: 1075 AENE-KLAEELELK----AAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELK 1129
Query: 490 ALENEVSALKSEIAA-----LQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEK 544
A ENE A + E+ A L ++ + E E L+ +++ EK L+ + E
Sbjct: 1130 AAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELKAAEN 1189
Query: 545 EKIVADSERKTAVDER-----KKAAAEARKLLEAAKKIAPEKAVIPEPANC-CSKCDELK 598
EK+ + E K A +E+ + AAE KL E + A E + E ++ ++L
Sbjct: 1190 EKLAEELELKVAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLA 1249
Query: 599 KKCEKVAVGRNALRQAVKIL----EKGIENLE---SENKKLKKENEVSALKSEISALQQK 651
++ E A L + +++ EK E LE +EN+KL +E E+ ++E L ++
Sbjct: 1250 EELELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKVAENE--KLAEE 1307
Query: 652 CGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDER-----KNA 706
A E E L+ +++ +K L+ + E E++ + E K A +E+ +
Sbjct: 1308 LELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELK 1367
Query: 707 AAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAE 766
AAE KL E + AAE EK ++EL+ EK E ++K A E K E E E
Sbjct: 1368 AAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAA-ENEKLAE-----ELE 1421
Query: 767 KKKLLVEKINAESKIKKAQ-ERSESELDKKTADMEKQQAEEQKKLAEDKLL 816
K EK+ E ++K A+ E+ EL+ K A+ EK E + K+AE++ L
Sbjct: 1422 LKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKVAENEKL 1472
Score = 144 bits (364), Expect = 9e-33
Identities = 183/755 (24%), Positives = 343/755 (45%), Gaps = 61/755 (8%)
Query: 33 NALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALI 92
N +Q +L + ++ E + L +++ A+ + E + E + S +
Sbjct: 910 NQFQQENDLLRQQLQQANDERENLHDRLEQLMAENQSLSEQLHNMHEELEREERDRSGVT 969
Query: 93 SENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKD 152
+N++L ++I + A+ + L+ + + RN Q +++E+ +E +EN+KL ++
Sbjct: 970 LQNERLAEEIQRKTAENEQL-VLENNKSRSDIRNLNVQVQRLMEE-LELKAAENEKLAEE 1027
Query: 153 IQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEI 212
++ + A+ + KL + ENE A + E K + + L E+ + K A KL
Sbjct: 1028 LELKAAENE-----KLAEELELKVAENEKLAEELELKVAENEKLAEELELKAAENEKLAE 1082
Query: 213 SNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILE 272
A ENE A + E K + + L E+ + K + EK+ E + L
Sbjct: 1083 ELELKAAENEKLAEELELKAAENEKLAEELELKAAEN-----EKLAEELELKAAENEKLA 1137
Query: 273 KGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDIL 332
+ +E +EN+KL ++++ + A+ + ++ +LE+ A ENE A + E K + + L
Sbjct: 1138 EELELKAAENEKLAEELELKAAENE-KLAEELELKVA----ENEKLAEELELKAAENEKL 1192
Query: 333 EEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEK 392
E+ + KVA KL A ENE A + E K + + L E+ + K + EK
Sbjct: 1193 AEELELKVAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAEN-----EK 1247
Query: 393 VVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENE 452
+ E + L + +E +EN+KL ++++ + A+ + ++ +LE+ A ENE
Sbjct: 1248 LAEELELKAAENEKLAEELELKVAENEKLAEELELKAAENE-KLAEELELKVA----ENE 1302
Query: 453 VSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAG 512
A + E + + L E+ ++KVA EKL A ENE A + E+ + + A
Sbjct: 1303 KLAEELELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKVAENEKLA- 1361
Query: 513 SREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDER-----KKAAAEA 567
E L+ ++ EK L+ + E EK+ + E K A +E+ + AAE
Sbjct: 1362 --------EELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAEN 1413
Query: 568 RKLLEAAKKIAPEKAVIPEPANC-CSKCDELKKKCEKVAVGRNALRQAVKIL----EKGI 622
KL E + A E + E ++ ++L ++ E A L + +++ EK
Sbjct: 1414 EKLAEELELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKVAENEKLA 1473
Query: 623 ENLE---SENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNR 679
E LE +EN+KL +E E+ A ++E L ++ A E E L+ +++ K+
Sbjct: 1474 EELELKAAENEKLAEELELKAAENE--KLAEELELKAAENEKLAEELELKVAENKRLAEE 1531
Query: 680 LKKEHVEEERIVADSERKTAVDERKNAA--AEARKLLEAPKKIAAEVEKQIAKVELRQVH 737
+ + E+E + D+ + + N+A + + L E +++E E +A +E V
Sbjct: 1532 VTQRLSEKELLAEDTSARLLEADSANSALQCKVKHLEEKLTLLSSEKETALATLEAEIVD 1591
Query: 738 LEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLV 772
L Q+ L+ T A + A K+K LV
Sbjct: 1592 LLTQLK--------GLNGTNSALESLCASKEKELV 1618
Score = 84.0 bits (206), Expect = 2e-14
Identities = 108/470 (22%), Positives = 218/470 (45%), Gaps = 60/470 (12%)
Query: 19 EELKKKCEQVVVGRNALRQAVKIL----EKGIENLE---SENKKLKKDIQEEQAQR-KVA 70
E+L ++ E V L + +++ EK E LE +EN+KL ++++ + A+ K+A
Sbjct: 1190 EKLAEELELKVAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLA 1249
Query: 71 IEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQG-KICDQLK----KCEKVVEGR 125
E +L+ + L E+ ++EN+KL +++ + A+ K+ ++L+ + EK+ E
Sbjct: 1250 EELELKAAEN-EKLAEELELKVAENEKLAEELELKAAENEKLAEELELKVAENEKLAEEL 1308
Query: 126 NALRQAVKILEKRIENLESENKKLKKDIQ---------EEQAQRKIEIEGKLEKSNAFAA 176
+ L + +E +EN+KL ++++ E+ + K+ KL + A
Sbjct: 1309 ELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELKA 1368
Query: 177 LENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQD 236
ENE A + E K + + L E+ + K A KL A ENE A + E K + +
Sbjct: 1369 AENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENE 1428
Query: 237 ILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQR 296
L E+ + K + EK+ E + L + +E +EN+KL ++++ + A+
Sbjct: 1429 KLAEELELKVAEN-----EKLAEELELKAAENEKLAEELELKVAENEKLAEELELKAAEN 1483
Query: 297 KVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALE 356
+ ++ +LE+ A ENE A + E K + + L E+ + KVA
Sbjct: 1484 E-KLAEELELK----AAENEKLAEELELKAAENEKLAEELELKVA--------------- 1523
Query: 357 NEVSALKSENKKLKQDILEEQAQGK-FCDQLKKKCEKVVEGRNALRQAVKILEKGIENLE 415
ENK+L +++ + ++ + + + + +AL+ VK LE+ + L
Sbjct: 1524 --------ENKRLAEEVTQRLSEKELLAEDTSARLLEADSANSALQCKVKHLEEKLTLLS 1575
Query: 416 SENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKK 465
SE + ++ E +++G ++ +ALE+ ++ + E L++
Sbjct: 1576 SEKETALATLEAEIVDLLTQLKG---LNGTNSALESLCASKEKELVFLRE 1622
>ref|XP_657028.1| myosin heavy chain [Entamoeba histolytica HM-1:IMSS]
gi|56474266|gb|EAL51645.1| myosin heavy chain [Entamoeba
histolytica HM-1:IMSS]
Length = 2151
Score = 155 bits (393), Expect = 4e-36
Identities = 199/824 (24%), Positives = 365/824 (44%), Gaps = 111/824 (13%)
Query: 48 NLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQA 107
N E E KK K+I E ++K+A E K A EN AL S K+ +
Sbjct: 870 NFEEEGKKKDKEI--EDLKKKLAEEIKKR-----EAAEN---ALASATAKI------GEL 913
Query: 108 QGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGK 167
+ KI D K ++ +A + L +IENLE + ++LK+ I + + K + K
Sbjct: 914 EAKIQDLEDKISELESKLSAAELDKQELNLKIENLEEDKEELKETIDKLKGDLK---DSK 970
Query: 168 LEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALK 227
L+ + LE+E++ L S+ L + ++ E E + L+ ++ L+
Sbjct: 971 LKGED----LEDEITELNSQINTLNATVDKKDKTIAEMQESIDEKEDEITKLKGDIKLLE 1026
Query: 228 SENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKK 287
E L+QD D A D + KK K+ + + LE+ +E+ E++NK L
Sbjct: 1027 EEKDDLEQDRADVSATK---DDIAKKLNKITIECEDAKDEIAKLEQELEDEENKNKDLTN 1083
Query: 288 DIQEEHAQRKVEIEGKLEISNAFAALENEVSALK---SENKKLKKDILEEQAQRKVAMEG 344
++Q+ +L++ +L +V+A K E L +++ E+ K +
Sbjct: 1084 ELQQT----------QLKLGETEKSLAAQVAATKKASDERDTLSQNLENEKLTTKNLTKT 1133
Query: 345 KLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQ-----------LKKKCE-- 391
K ++ + L+ + L+ + K++ D+ Q + K D L+K+ E
Sbjct: 1134 KADLEKKISGLKQDYEDLEDDKNKIEGDLRNAQRKIKELDDEITKGADVSQYLQKQKEEY 1193
Query: 392 -----KVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAF 446
K+ E + A+ VK EK I+ E E + L++ + E + +++ + K EI
Sbjct: 1194 ESQIAKMQEEKEAIGNDVKNKEKTIKEKELEIQSLQEKLDETEVEKEDAEKKKKEIEKEM 1253
Query: 447 AALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENE-VSALKSEIAAL 505
AL+ E ++S +KD + + +K ++KL+ A +NE + A ++ A
Sbjct: 1254 KALQEEKENVESSKNSTEKDKKKLEDNLK-DTQKKLDDMTA----DNEKLKAKAKDLEAQ 1308
Query: 506 QQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKEL--VEKEKIVADSERKTAVDER--- 560
+ + D E+L + ++KE+N+LK EL + K K V +S+ K + +E+
Sbjct: 1309 LNEVQDNHEKAVADAELLNKKKAQSDKELNSLKAELEALTKAKSVVESKNKDSENEKAAL 1368
Query: 561 -----------KKAAAEARK----LLEAAKKIAPEKA----VIPEPANCCSKCDELKKKC 601
K A+ RK L EA +K A +A ++ + +E+K +
Sbjct: 1369 SEEIDQANEKLKNIQADLRKATADLQEANEKKAEVEAQRDKLVADNKKMTKTLEEIKARD 1428
Query: 602 E----KVAVGRNALRQAVKILEKGIENLESENK-KLKKENEVSALKSEISALQQKCGAGA 656
E KV L++ LE+ ENL+ E K ++ KE +V L+ E+ + K A
Sbjct: 1429 EENTYKVENYEKVLKRKEADLEEANENLDIEKKDRMNKEKQVKKLEGELKETKDKLNAAI 1488
Query: 657 REGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAA-----EAR 711
E + K +D +E+N+ +EH + +VA + R N +A E R
Sbjct: 1489 AEKDSIFTAKKQSDADL-EELNKTVEEH---DEVVAKLNTQITKLTRDNQSAEEELNELR 1544
Query: 712 KLLEAPKKIAAEVEKQIAKVELRQVHL----EKQVNERKMKLAFELSKTKE----ATKRF 763
+ KK +E+E+Q+ ++E R V E ++ R ++A +L+K E +
Sbjct: 1545 SKADKDKKKISELEEQVNELESRPVGTGNADENEIKIRDAQIA-DLNKALEMKGDQNNQL 1603
Query: 764 EAEKKKLLVEKINAESKIKKAQ-ERSESELDKKTADMEKQQAEE 806
+A K+L + + SKI+ + E + E KK + +K +A++
Sbjct: 1604 QATNKELKAKNNDLTSKIEITENEMKKLENAKKRLEQDKDEADK 1647
Score = 144 bits (363), Expect = 1e-32
Identities = 164/710 (23%), Positives = 325/710 (45%), Gaps = 73/710 (10%)
Query: 130 QAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENK 189
+A +L++R N E E KK K+I++ + + EI+ + NA A+ ++ L+++ +
Sbjct: 861 KARPMLKRR--NFEEEGKKKDKEIEDLKKKLAEEIKKREAAENALASATAKIGELEAKIQ 918
Query: 190 KLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDR 249
L+ I E +++ A K E++ LE + LK KLK D+ D + +G
Sbjct: 919 DLEDKISELESKLSAAELDKQELNLKIENLEEDKEELKETIDKLKGDLKDSKLKG----- 973
Query: 250 LKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNA 309
E+LE E +L I +A + + E+ +
Sbjct: 974 --------------------------EDLEDEITELNSQINTLNATVDKKDKTIAEMQES 1007
Query: 310 FAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKL 369
E+E++ LK + K L+++ + + R K +I+ + E K E KL
Sbjct: 1008 IDEKEDEITKLKGDIKLLEEEKDDLEQDRADVSATKDDIAKKLNKITIECEDAKDEIAKL 1067
Query: 370 KQDILEEQAQGK-FCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEE 428
+Q++ +E+ + K ++L++ K+ E +L V +K E L ++++ E
Sbjct: 1068 EQELEDEENKNKDLTNELQQTQLKLGETEKSLAAQVAATKKA----SDERDTLSQNLENE 1123
Query: 429 QAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAF 488
+ K + K ++ + L+ + L+ + K++ D+ Q +IK +E + ++
Sbjct: 1124 KLTTKNLTKTKADLEKKISGLKQDYEDLEDDKNKIEGDLRNAQRKIKELDDEITKGADVS 1183
Query: 489 AALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIV 548
L+ + +S+IA +Q++ A GN DV+ + I + E E+ +L+++L E E
Sbjct: 1184 QYLQKQKEEYESQIAKMQEEKEA---IGN-DVKNKEKTIKEKELEIQSLQEKLDETEVEK 1239
Query: 549 ADSE-RKTAVDERKKAAAEARKLLEAAKKIA--PEKAVIPEPANCCSKCDELKKKCEKVA 605
D+E +K +++ KA E ++ +E++K +K + + K D++ EK+
Sbjct: 1240 EDAEKKKKEIEKEMKALQEEKENVESSKNSTEKDKKKLEDNLKDTQKKLDDMTADNEKLK 1299
Query: 606 VGRNALRQAVKIL----EKGIENLESEN-KKLKKENEVSALKSEISALQQKCGAGAREGN 660
L + + EK + + E N KK + + E+++LK+E+ AL K + N
Sbjct: 1300 AKAKDLEAQLNEVQDNHEKAVADAELLNKKKAQSDKELNSLKAELEAL-TKAKSVVESKN 1358
Query: 661 GDVEVLKAGISDTKKEVN-RLKKEHVEEERIVAD----SERKTAVD-ERKNAAAEARKLL 714
D E KA +S+ + N +LK + + AD +E+K V+ +R A+ +K+
Sbjct: 1359 KDSENEKAALSEEIDQANEKLKNIQADLRKATADLQEANEKKAEVEAQRDKLVADNKKMT 1418
Query: 715 EAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEK 774
+ ++I A E+ KVE + EK + ++ L +EA + + EKK ++
Sbjct: 1419 KTLEEIKARDEENTYKVE----NYEKVLKRKEADL-------EEANENLDIEKK----DR 1463
Query: 775 INAESKIKKAQERSESELDKKTADM-EKQQAEEQKKLAEDKLLLLGDSLQ 823
+N E ++KK + + DK A + EK KK ++ L L +++
Sbjct: 1464 MNKEKQVKKLEGELKETKDKLNAAIAEKDSIFTAKKQSDADLEELNKTVE 1513
Score = 137 bits (346), Expect = 1e-30
Identities = 183/818 (22%), Positives = 370/818 (44%), Gaps = 82/818 (10%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEIS 78
EE + + ++ + A+ VK EK I+ E E + L++ + E + +++ A + K EI
Sbjct: 1191 EEYESQIAKMQEEKEAIGNDVKNKEKTIKEKELEIQSLQEKLDETEVEKEDAEKKKKEIE 1250
Query: 79 NTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKR 138
AL+ E + S ++D +++ + + D KK + + L+ K LE +
Sbjct: 1251 KEMKALQEEKENVESSKNSTEKD--KKKLEDNLKDTQKKLDDMTADNEKLKAKAKDLEAQ 1308
Query: 139 IENLESENKKLKKD---IQEEQAQR-------KIEIEGKLEKSNAFAAL----ENEVSAL 184
+ ++ ++K D + +++AQ K E+E + + + ENE +AL
Sbjct: 1309 LNEVQDNHEKAVADAELLNKKKAQSDKELNSLKAELEALTKAKSVVESKNKDSENEKAAL 1368
Query: 185 KSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQG 244
E + + + QA + A E + A +E + L ++NKK+ + + + +A+
Sbjct: 1369 SEEIDQANEKLKNIQADLRKATADLQEANEKKAEVEAQRDKLVADNKKMTKTLEEIKARD 1428
Query: 245 KFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENK-KLKKDIQEEHAQRKVEIEGK 303
+ + EKV++ + A LE+ ENL+ E K ++ K+ Q + + +++ E K
Sbjct: 1429 EENTYKVENYEKVLKRKEA------DLEEANENLDIEKKDRMNKEKQVKKLEGELK-ETK 1481
Query: 304 LEISNAFAALENEVSALKSENKKLKK--DILEEQAQRKVAMEGKL-EISNAFAALENEVS 360
+++ A A ++ +A K + L++ +EE + + ++ +++ + E E++
Sbjct: 1482 DKLNAAIAEKDSIFTAKKQSDADLEELNKTVEEHDEVVAKLNTQITKLTRDNQSAEEELN 1541
Query: 361 ALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQA-VKILEKGIENLESENK 419
L+S+ K K+ I E + Q + E +R A + L K +E +N
Sbjct: 1542 ELRSKADKDKKKISELEEQVNELESRPVGTGNADENEIKIRDAQIADLNKALEMKGDQNN 1601
Query: 420 KLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILE-EQAQIKVAI 478
+L+ +E +A+ ++ K+EI+ ENE+ L++ +L++D E ++A + I
Sbjct: 1602 QLQATNKELKAKNN-DLTSKIEIT------ENEMKKLENAKKRLEQDKDEADKAVSEQTI 1654
Query: 479 EEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLK 538
+ K LE EV L +EI AL+ + A S + + E ++ LK
Sbjct: 1655 KRK--------GLEEEVKKLTTEIQALKFQINAPSSVAQEEEK------QRLESDIAELK 1700
Query: 539 KELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELK 598
++L ++ A++E ERKK AE ++ + + ++ ++L
Sbjct: 1701 EQLEQERTTAANAEA-----ERKKIQAELDEVKFNLEDVTNQR-------------EKLV 1742
Query: 599 KKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGARE 658
K + ++L++ K LE IE + +N KL +E I +L +K A
Sbjct: 1743 AKNSENDAEIDSLKEEKKALEDEIEKITDDNNKLNEE---------IDSLDRKYNALLDS 1793
Query: 659 GNGDV---EVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLE 715
+ DV E + + TK + KK H E R+ E++ A + + A + L
Sbjct: 1794 KDSDVSMKEKFQDELKVTKDALETEKKNHAETMRLKGRLEKEAAEVQVRLEALQKNLDLA 1853
Query: 716 APKKIAAEVEKQIAKVELRQVHLE-KQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEK 774
+K A + + A EL+ + E V ++ K +L+ ++ + + K L+ +K
Sbjct: 1854 QQEKAKATKDYRAADGELKSLMNELDDVKDQLDKAQDDLADKEDELATLDQKYKTLVKQK 1913
Query: 775 INAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAE 812
+S+I++ QE+ + E + A +KQ+ +KKL E
Sbjct: 1914 SVFDSRIQEMQEQLDLEKAGR-AKAQKQKQAYEKKLQE 1950
Score = 129 bits (324), Expect = 4e-28
Identities = 188/875 (21%), Positives = 386/875 (43%), Gaps = 117/875 (13%)
Query: 17 KCEELKKKCEQVVVGRNALRQAVKILEKGIENLES---ENKKLKKDIQEEQAQRKVAIEG 73
K +E + + E + + + +K L++ EN+ES +K KK +++ + ++
Sbjct: 1231 KLDETEVEKEDAEKKKKEIEKEMKALQEEKENVESSKNSTEKDKKKLEDNLKDTQKKLDD 1290
Query: 74 KLEISNTFAALENEVSALISE---------------NKKLKQDILEEQAQGKICDQLKKC 118
+ A ++ A ++E NKK Q E + + L K
Sbjct: 1291 MTADNEKLKAKAKDLEAQLNEVQDNHEKAVADAELLNKKKAQSDKELNSLKAELEALTKA 1350
Query: 119 EKVVEGRN--------ALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEK 170
+ VVE +N AL + + ++++N++++ +K D+QE ++K E+E + +K
Sbjct: 1351 KSVVESKNKDSENEKAALSEEIDQANEKLKNIQADLRKATADLQEAN-EKKAEVEAQRDK 1409
Query: 171 SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSEN 230
L ++NKK+ K + E +A+ + E ++ N L+ + + L+ N
Sbjct: 1410 -------------LVADNKKMTKTLEEIKARDE---ENTYKVENYEKVLKRKEADLEEAN 1453
Query: 231 KKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQ 290
+ L + D + K +L+ + ++ + NA + + +++ ++L K +
Sbjct: 1454 ENLDIEKKDRMNKEKQVKKLEGELKETKDKLNAAIAEKDSIFTAKKQSDADLEELNKTV- 1512
Query: 291 EEHAQRKVEIEGKL-EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEIS 349
EEH + ++ ++ +++ + E E++ L+S+ K KK I E + Q +
Sbjct: 1513 EEHDEVVAKLNTQITKLTRDNQSAEEELNELRSKADKDKKKISELEEQVNELESRPVGTG 1572
Query: 350 NAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEK 409
NA ENE+ ++ L + + + +G +QL+ +++ N L ++I E
Sbjct: 1573 NAD---ENEIKIRDAQIADLNKAL---EMKGDQNNQLQATNKELKAKNNDLTSKIEITEN 1626
Query: 410 GIENLESENKKLKKD-------IQEEQAQRKIEIEGKLEISNAFAALENEVSALKS---- 458
++ LE+ K+L++D + E+ +RK E +++ AL+ +++A S
Sbjct: 1627 EMKKLENAKKRLEQDKDEADKAVSEQTIKRKGLEEEVKKLTTEIQALKFQINAPSSVAQE 1686
Query: 459 -ESTKLKKDILEEQAQIKVAIEEKLEISNAFA------ALENEVSALKSEIAALQQKCGA 511
E +L+ DI E + Q++ +E+ +NA A A +EV ++ ++K A
Sbjct: 1687 EEKQRLESDIAELKEQLE---QERTTAANAEAERKKIQAELDEVKFNLEDVTNQREKLVA 1743
Query: 512 GSREGNGDVEVLKAGISDTEKEV-------NTLKKE-----------LVEKEKIVADSER 553
+ E + +++ LK E E+ N L +E L K+ V+ E+
Sbjct: 1744 KNSENDAEIDSLKEEKKALEDEIEKITDDNNKLNEEIDSLDRKYNALLDSKDSDVSMKEK 1803
Query: 554 --------KTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVA 605
K A++ KK AE +L +K A E V E D +++ K
Sbjct: 1804 FQDELKVTKDALETEKKNHAETMRLKGRLEKEAAEVQVRLEALQ--KNLDLAQQEKAKAT 1861
Query: 606 VGRNALRQAVKILEKGIENLESENKKLK-----KENEVSALKSEISAL-QQKCGAGAR-- 657
A +K L +++++ + K + KE+E++ L + L +QK +R
Sbjct: 1862 KDYRAADGELKSLMNELDDVKDQLDKAQDDLADKEDELATLDQKYKTLVKQKSVFDSRIQ 1921
Query: 658 EGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVAD-SERKTAVDERKNAAA----EARK 712
E +++ KAG + +K+ +K+ E + D E K D+R N + + +K
Sbjct: 1922 EMQEQLDLEKAGRAKAQKQKQAYEKKLQELQENDNDFEEYKETADKRINTLSAQKDDLQK 1981
Query: 713 LLEAPKKIAAEVEKQIAKVELRQVHLEKQVNE---RKMKLAFELSKTKEATKRFEAEKKK 769
LE + + + EK++ ++ ++ LE +V E + +A +K + + E +
Sbjct: 1982 ELEKERGLKQDSEKEVQRLRVKCQELETKVAEVGGANVSIAKVKAKYEAEIEELTTEAED 2041
Query: 770 LLVEKINAESKIKKAQERSESELDKKTADMEKQQA 804
L K+ AE K K +Q++ + EL K AD E ++A
Sbjct: 2042 ALKAKMKAEKKAKTSQKKLD-ELQKTIADYETKEA 2075
Score = 99.4 bits (246), Expect = 4e-19
Identities = 162/652 (24%), Positives = 280/652 (42%), Gaps = 102/652 (15%)
Query: 16 SKCEELKKKCEQVVVGR-NALRQAVKI-------LEKGIENLESENKKLKKDIQEEQAQR 67
S+ EE + E VG NA +KI L K +E +N +L+ +E +A+
Sbjct: 1555 SELEEQVNELESRPVGTGNADENEIKIRDAQIADLNKALEMKGDQNNQLQATNKELKAKN 1614
Query: 68 KVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNA 127
+ K+EI+ ENE+ L + K+L+QD +++A + +Q K R
Sbjct: 1615 N-DLTSKIEIT------ENEMKKLENAKKRLEQD--KDEADKAVSEQTIK-------RKG 1658
Query: 128 LRQAVKILEKRIENLESENKKLKKDIQEEQAQRK----IEIEGKLEKSNAFAA-LENEVS 182
L + VK L I+ L+ + QEE+ QR E++ +LE+ AA E E
Sbjct: 1659 LEEEVKKLTTEIQALKFQINAPSSVAQEEEKQRLESDIAELKEQLEQERTTAANAEAERK 1718
Query: 183 ALKSENKKLKKDILEEQAQRKVAMEGKLE-------ISNAFAALENEVSALKSENKKLKQ 235
+++E ++K ++ + QR+ + E + ALE+E+ + +N KL +
Sbjct: 1719 KIQAELDEVKFNLEDVTNQREKLVAKNSENDAEIDSLKEEKKALEDEIEKITDDNNKLNE 1778
Query: 236 DILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLE---SENKKLKKDIQEE 292
+I + K+ L K + V + + +K+ + +E + +E +LK +++E
Sbjct: 1779 EI--DSLDRKYNALLDSK-DSDVSMKEKFQDELKVTKDALETEKKNHAETMRLKGRLEKE 1835
Query: 293 HAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAF 352
A+ +V +E AL+ + + E K KD A +G+L+
Sbjct: 1836 AAEVQVRLE----------ALQKNLDLAQQEKAKATKDYR--------AADGELK----- 1872
Query: 353 AALENEVSALKSENKKLKQDILEEQAQGKFCDQLKK---KCEKVVEGRNALRQAVKILEK 409
+L NE+ +K + K + D+ +++ + DQ K K + V + R Q LEK
Sbjct: 1873 -SLMNELDDVKDQLDKAQDDLADKEDELATLDQKYKTLVKQKSVFDSRIQEMQEQLDLEK 1931
Query: 410 -GIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTK---LKK 465
G + + + +K +QE Q E K L + L+ E K LK+
Sbjct: 1932 AGRAKAQKQKQAYEKKLQELQENDNDFEEYKETADKRINTLSAQKDDLQKELEKERGLKQ 1991
Query: 466 DILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKA 525
D +E +++V +E LE A EV IA ++ K A E + E
Sbjct: 1992 DSEKEVQRLRVKCQE-LETKVA------EVGGANVSIAKVKAKYEAEIEELTTEAEDALK 2044
Query: 526 GISDTEKEVNTLKKELVEKEKIVADSERKTAVDERK--KAAAEARKLLEAAKKIAPEKAV 583
EK+ T +K+L E +K +AD E K A + K AE +K ++ V
Sbjct: 2045 AKMKAEKKAKTSQKKLDELQKTIADYETKEASFNTQIGKTQAELKKY---------QQQV 2095
Query: 584 IPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKE 635
+ S DE+KK G +AL A K LE ++ + + +KLKK+
Sbjct: 2096 RDDETRMSSLEDEIKK-------GTDAL--ANKQLE--LDKVNKQYEKLKKQ 2136
>gb|EAA53821.1| hypothetical protein MG09571.4 [Magnaporthe grisea 70-15]
gi|39961876|ref|XP_364726.1| hypothetical protein
MG09571.4 [Magnaporthe grisea 70-15]
Length = 709
Score = 155 bits (393), Expect = 4e-36
Identities = 188/707 (26%), Positives = 329/707 (45%), Gaps = 91/707 (12%)
Query: 121 VVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENE 180
+V+ + L A K LE+ LE++ KK +D+ ++ K ++ +++ NA +
Sbjct: 47 LVQRADELAAAKKPLEEEKTELEAKLKKASEDLSTRDSEIK-DLLKNIDQVNA------K 99
Query: 181 VSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDE 240
V +LK E + + + E Q ++ A + LE ALE + L ++ +KLK ++ D
Sbjct: 100 VESLKKEKAAVDQQLAEAQKGKEGAQKETLE---KIDALEKAKAELNAQVEKLKSEVADV 156
Query: 241 QAQGKFCDRLKKKCEKVVEGRNALRQAVKI-LEKGIENLESENKKLKKDIQ---EEHAQR 296
++ D L+++ K++E N+ + +K L+ I L S+ K D+ EE A
Sbjct: 157 SSKN---DSLRQEQSKLLEETNSAKDTLKAELDAKIVALTSDLDAAKADLSRANEEAATT 213
Query: 297 KVEIEGKLEISNA-FAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISN-AFAA 354
K ++E +++ A A + + A S+ + K + + +E LE +N +
Sbjct: 214 KTKLEEQVKTLQAELDATKKDAQAAASKGTEEAKSEVTSLNTKIAKLEEDLEAANKSTET 273
Query: 355 LENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENL 414
+ E + LK++ KL++D+ ++Q Q + +K ++ NA QA K E+L
Sbjct: 274 AQAEAATLKTKISKLEEDLAAAKSQSDKLTQEAEAQKKSLDDANAQIQAKT---KETEDL 330
Query: 415 ESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQI 474
++ K + + E+QA + + + E+++ ++L+++ SA S L+
Sbjct: 331 LAKLKAAEASVAEKQASLE---KTQAELTSTKSSLDSDKSAGAEASKALEA--------- 378
Query: 475 KVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEV 534
EK + A A + SAL++E QK A +++ VEV KA +D +K V
Sbjct: 379 -----EKASRAEAEKAAADAKSALEAE-----QKAHADAKKA---VEVEKAAAADAKKAV 425
Query: 535 NTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPE--KAVIPEPANCCS 592
E EK A +E KTA++ KKA AE + LE K A E K++ E A+
Sbjct: 426 --------EAEK-TAHAETKTALEAEKKAHAETKTALETEKIAAAEAKKSLDSEKASKAD 476
Query: 593 KCDELKKKCEKVAVGRNALRQAVKILEKGIENLESE-----NKKLKKENEVSALKSEISA 647
L+ + VA + A+ K + LE+E + K E+E S + A
Sbjct: 477 ANSALETQKSAVADAQKAVEAEKKAHAETKSALEAEKTAAADAKKAVESEKSTAQEAQKA 536
Query: 648 LQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERI-----VADSERKTAVDE 702
L+ + A A E E + +++ +K + K H E ++ A ++ K A+D
Sbjct: 537 LEAEKAAHA-ETKKSSEAGTSAVTEAQKALESEKAAHAEAKKASEADKAALADAKKALDA 595
Query: 703 RKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKR 762
K AAA+A+K LEA K AA+ +K LE + K L E + TKEA K
Sbjct: 596 EKAAAADAQKALEAEKAAAADAKKA----------LEAEKASAKKALETETAATKEAKKA 645
Query: 763 FEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKK 809
E +A+SK+KKA+E +++ L+K+ AD EK+ E K
Sbjct: 646 AE-----------DAQSKLKKAEEDTKA-LNKRVADAEKESKELSTK 680
Score = 135 bits (339), Expect = 7e-30
Identities = 153/664 (23%), Positives = 283/664 (42%), Gaps = 84/664 (12%)
Query: 177 LENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQD 236
L+ +V L+ + K + + K ++ E++ A LE E + L+++ KK +D
Sbjct: 19 LQTKVKELQEKLDATKTQLDTRDSDIKTLVQRADELAAAKKPLEEEKTELEAKLKKASED 78
Query: 237 ILDEQAQGKFC----DRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEE 292
+ ++ K D++ K E + + + A+ Q + +KG E + E + +++
Sbjct: 79 LSTRDSEIKDLLKNIDQVNAKVESLKKEKAAVDQQLAEAQKGKEGAQKETLEKIDALEKA 138
Query: 293 HAQRKVEIEGKL-----EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLE 347
A+ ++E KL ++S+ +L E S L E K + E + VA+ L+
Sbjct: 139 KAELNAQVE-KLKSEVADVSSKNDSLRQEQSKLLEETNSAKDTLKAELDAKIVALTSDLD 197
Query: 348 ISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVV-EGRNALRQAVKI 406
+ A + NE +A + KL++ + QA+ D KK + +G + V
Sbjct: 198 AAKADLSRANEEAA--TTKTKLEEQVKTLQAE---LDATKKDAQAAASKGTEEAKSEVTS 252
Query: 407 LEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKL--- 463
L I LE + + K + QA+ + + LE +++A KS+S KL
Sbjct: 253 LNTKIAKLEEDLEAANKSTETAQAEAAT-------LKTKISKLEEDLAAAKSQSDKLTQE 305
Query: 464 ----KKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGD 519
KK + + AQI+ +E ++ A E V+ ++ + Q + + + D
Sbjct: 306 AEAQKKSLDDANAQIQAKTKETEDLLAKLKAAEASVAEKQASLEKTQAELTSTKSSLDSD 365
Query: 520 VEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAP 579
K+ ++ K + K E EK AD+ K+A++ +KA A+A+K +E K A
Sbjct: 366 ----KSAGAEASKALEAEKASRAEAEKAAADA--KSALEAEQKAHADAKKAVEVEKAAAA 419
Query: 580 EKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVS 639
+ KK E + A++ +K +E K + +++
Sbjct: 420 DA----------------KKAVEAEKTAHAETKTALEAEKKA----HAETKTALETEKIA 459
Query: 640 ALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTA 699
A +++ S +K A + N +E K+ ++D +K V KK H +E K+A
Sbjct: 460 AAEAKKSLDSEK--ASKADANSALETQKSAVADAQKAVEAEKKAH---------AETKSA 508
Query: 700 VDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEA 759
++ K AAA+A+K +E+ K A E +K + E + E K+ EA
Sbjct: 509 LEAEKTAAADAKKAVESEKSTAQEAQKAL---------------EAEKAAHAETKKSSEA 553
Query: 760 TKRFEAEKKKLLVEKINAESKIKKAQERSESELD--KKTADMEKQQAEEQKKLAEDKLLL 817
E +K L + A ++ KKA E ++ L KK D EK A + +K E +
Sbjct: 554 GTSAVTEAQKALESEKAAHAEAKKASEADKAALADAKKALDAEKAAAADAQKALEAEKAA 613
Query: 818 LGDS 821
D+
Sbjct: 614 AADA 617
Score = 124 bits (311), Expect = 1e-26
Identities = 147/607 (24%), Positives = 270/607 (44%), Gaps = 67/607 (11%)
Query: 213 SNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILE 272
S++ ++ + L+++ K+L++ + + Q D + +V+ + L A K LE
Sbjct: 6 SSSTSSGSGDSKELQTKVKELQEKLDATKTQ---LDTRDSDIKTLVQRADELAAAKKPLE 62
Query: 273 KGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDIL 332
+ LE++ KK +D+ ++ K ++ ++ NA +V +LK E + + +
Sbjct: 63 EEKTELEAKLKKASEDLSTRDSEIK-DLLKNIDQVNA------KVESLKKEKAAVDQQLA 115
Query: 333 EEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEK 392
E Q ++ A + LE ALE + L ++ +KLK ++ + ++ D L+++ K
Sbjct: 116 EAQKGKEGAQKETLE---KIDALEKAKAELNAQVEKLKSEVADVSSKN---DSLRQEQSK 169
Query: 393 VVEGRNALRQAVKI-LEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALEN 451
++E N+ + +K L+ I L S+ K D+ E + LE
Sbjct: 170 LLEETNSAKDTLKAELDAKIVALTSDLDAAKADLSRANE----------EAATTKTKLEE 219
Query: 452 EVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGA 511
+V L++E KKD QA EE ++EV++L ++IA L++ A
Sbjct: 220 QVKTLQAELDATKKDA---QAAASKGTEEA----------KSEVTSLNTKIAKLEEDLEA 266
Query: 512 GSRE---GNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEAR 568
++ + LK IS E+++ K + +K A++++K+ D + A+ +
Sbjct: 267 ANKSTETAQAEAATLKTKISKLEEDLAAAKSQS-DKLTQEAEAQKKSLDDANAQIQAKTK 325
Query: 569 KLLEAAKKIAPEKAVIPEPANCCSKCD-ELKKKCEKVAVGRNALRQAVKILEKGIENLES 627
+ + K+ +A + E K EL + ++A +A K LE
Sbjct: 326 ETEDLLAKLKAAEASVAEKQASLEKTQAELTSTKSSLDSDKSAGAEASKALEA------E 379
Query: 628 ENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEE 687
+ + + E + KS + A +QK A A++ VEV KA +D KK V K H
Sbjct: 380 KASRAEAEKAAADAKSALEA-EQKAHADAKKA---VEVEKAAAADAKKAVEAEKTAH--- 432
Query: 688 ERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKM 747
+E KTA++ K A AE + LE K AAE +K + + + + +K
Sbjct: 433 ------AETKTALEAEKKAHAETKTALETEKIAAAEAKKSLDSEKASKADANSALETQKS 486
Query: 748 KLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKA--QERSESELDKKTADMEKQQAE 805
+A + K EA K+ AE K L + A + KKA E+S ++ +K + EK
Sbjct: 487 AVA-DAQKAVEAEKKAHAETKSALEAEKTAAADAKKAVESEKSTAQEAQKALEAEKAAHA 545
Query: 806 EQKKLAE 812
E KK +E
Sbjct: 546 ETKKSSE 552
Score = 120 bits (301), Expect = 2e-25
Identities = 179/757 (23%), Positives = 327/757 (42%), Gaps = 126/757 (16%)
Query: 20 ELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKD---IQEEQAQRKVAIEG-KL 75
EL+ K ++ + +K L K I+ + ++ + LKK+ + ++ A+ + EG +
Sbjct: 67 ELEAKLKKASEDLSTRDSEIKDLLKNIDQVNAKVESLKKEKAAVDQQLAEAQKGKEGAQK 126
Query: 76 EISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE-KVVEGRNALRQAVKI 134
E ALE + L ++ +KLK ++ + ++ D L++ + K++E N+ + +K
Sbjct: 127 ETLEKIDALEKAKAELNAQVEKLKSEVADVSSKN---DSLRQEQSKLLEETNSAKDTLKA 183
Query: 135 -LEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKK 193
L+ +I L S+ K D+ E + LE +V L++E KK
Sbjct: 184 ELDAKIVALTSDLDAAKADLSRANE----------EAATTKTKLEEQVKTLQAELDATKK 233
Query: 194 DILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKK 253
D + A K E K +EV++L ++ KL++D+ + K
Sbjct: 234 D--AQAAASKGTEEAK-----------SEVTSLNTKIAKLEEDL----------EAANKS 270
Query: 254 CEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNA-FAA 312
E L+ + LE+ + +S++ KL QE AQ+K L+ +NA A
Sbjct: 271 TETAQAEAATLKTKISKLEEDLAAAKSQSDKL---TQEAEAQKK-----SLDDANAQIQA 322
Query: 313 LENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQD 372
E L ++ K + + E+QA + + + E+++ ++L+++ SA +K L+ +
Sbjct: 323 KTKETEDLLAKLKAAEASVAEKQASLE---KTQAELTSTKSSLDSDKSAGAEASKALEAE 379
Query: 373 ILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQR 432
+ + +A K LE+E K A++
Sbjct: 380 ------------------------KASRAEAEKAAADAKSALEAEQK------AHADAKK 409
Query: 433 KIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIE-EKLEISNAFAAL 491
+E+E K ++A A+E E +A T L+ + + A+ K A+E EK+ + A +L
Sbjct: 410 AVEVE-KAAAADAKKAVEAEKTAHAETKTALEAE-KKAHAETKTALETEKIAAAEAKKSL 467
Query: 492 ENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADS 551
++E ++ +AL E K+ ++D +K V KK A +
Sbjct: 468 DSEKASKADANSAL---------------ETQKSAVADAQKAVEAEKK---------AHA 503
Query: 552 ERKTAVDERKKAAAEARKLLEAAKKIAPE--KAVIPEPANCCSKCDELKKKCEKVAVGRN 609
E K+A++ K AAA+A+K +E+ K A E KA+ E A E KK E G +
Sbjct: 504 ETKSALEAEKTAAADAKKAVESEKSTAQEAQKALEAEKAAHA----ETKKSSE---AGTS 556
Query: 610 ALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAG 669
A+ +A K LE E K E + +AL AL + A A + +E KA
Sbjct: 557 AVTEAQKALES--EKAAHAEAKKASEADKAALADAKKALDAE-KAAAADAQKALEAEKAA 613
Query: 670 ISDTKK--EVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQ 727
+D KK E + + E A E K A ++ ++ +A + +A K A+ EK+
Sbjct: 614 AADAKKALEAEKASAKKALETETAATKEAKKAAEDAQSKLKKAEEDTKALNKRVADAEKE 673
Query: 728 IAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFE 764
++ + E + E + K+ ELS+ K+ + E
Sbjct: 674 SKELSTKATAAESRTKELEAKVK-ELSEQKKEEAKAE 709
>ref|XP_654864.1| hypothetical protein 42.t00003 [Entamoeba histolytica HM-1:IMSS]
gi|56471951|gb|EAL49477.1| hypothetical protein 42.t00003
[Entamoeba histolytica HM-1:IMSS]
Length = 1575
Score = 155 bits (391), Expect = 7e-36
Identities = 200/792 (25%), Positives = 350/792 (43%), Gaps = 122/792 (15%)
Query: 47 ENLESENKKLKKDIQEEQ------------AQRKVAIEGKLEISNTFAALENEVS--ALI 92
E++ NK+L++ +E+Q A + VA KL S L S A I
Sbjct: 660 EDINGVNKELQQGNEEDQCVKPSSMGLKSSAAQIVAQRKKLPKSGKNNTLTGSASLNAYI 719
Query: 93 SENKKLKQDILEEQAQGKI-CDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKK 151
++ KQD +E + KI + +K E++ ++ +R K E E ++KK ++
Sbjct: 720 QRQEQYKQDEIERE---KIRMEMQRKREEIQRKQDEIR-------KMREETEKQHKKGEE 769
Query: 152 DIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDIL--EEQAQRKVAMEGK 209
+++E+ + K E E + +K E E ENK++K++ EE+ ++K A E +
Sbjct: 770 RLKQEEERFKKEEEERKKKEEERLRQEEE------ENKRIKEERQRKEEELRKKKAEEER 823
Query: 210 LEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVK 269
LE E K E ++ K+ E+ + K + LKKK E+ + + A+ K
Sbjct: 824 KR------KLEEEARKRKEEEEQRKE----EEEKRKVEEELKKKEEEERKRKEAIELKKK 873
Query: 270 ILEKGIENLESENKKL----KKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENK 325
LE+ + E E KK +K +EE +++E E + ++ E + K E +
Sbjct: 874 QLEEERKKKEEERKKREEEERKKEEEEERLKQIEQEKQRKLEEERKKKEEAIKRKKEEEE 933
Query: 326 KLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQ 385
+ +K EE+ +++ E K + E E K E K K +E++ Q K ++
Sbjct: 934 RKRK---EEERRKREEAERKRK--------EEEERKRKEEEAKRK---IEQERQRKIEEE 979
Query: 386 LKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNA 445
+KK E E + L + K+LE+ + LE E +K E+ ++++E E K +
Sbjct: 980 RRKKEE---EEQRRLEEEKKLLEEEQKRLEEEERKA------EEERKRVEAERKRKEEEE 1030
Query: 446 FAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAAL 505
E E K E K K++ EE+ + + + K E+ E E + E+
Sbjct: 1031 RKRKEEEERKRKEEERKRKEE--EERKRKEEEEKRKKELEELKKLKEEERRKKEEELKRK 1088
Query: 506 QQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAA 565
Q++ E KA KE K++ E+E+ + E++ A +ERK+
Sbjct: 1089 QEE------------EKRKAEAERKRKEEEERKRK-EEEERKRKEEEKRKAEEERKRKEE 1135
Query: 566 EARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENL 625
E RK EA +K K + E K +EL+KK E+ R E
Sbjct: 1136 ELRKKKEAEEK----KRKLEEEHK--KKEEELRKKKEEEEKRRQEE-----------EKR 1178
Query: 626 ESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHV 685
++E ++ +KE E A K E +++ + E K K+E KK+
Sbjct: 1179 KAEEERKRKEEEEKARKEEEERIKR-----------EEEERK------KQEEEERKKKEE 1221
Query: 686 EEERIVADSERKTAVDE---RKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQV 742
EE R+ + E+K +E R+ A RK EA KK EVE+ ++E + L++
Sbjct: 1222 EELRVKQEEEKKKRAEEEEKRRRAEERKRKEEEARKKEEEEVERLKKELEEEERKLKEAE 1281
Query: 743 NERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQ 802
ERK A K +E KR E EK+K E+ + + +KA++ E + ++ + ++
Sbjct: 1282 EERKRIEAERKRKEEEKKKREEEEKRKREEEERKRKEEEEKARKEEEEKRKREDEERMRR 1341
Query: 803 QAEEQKKLAEDK 814
EE++K E++
Sbjct: 1342 HEEERRKWEEEQ 1353
Score = 140 bits (353), Expect = 2e-31
Identities = 202/773 (26%), Positives = 341/773 (43%), Gaps = 83/773 (10%)
Query: 21 LKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNT 80
LK Q+V R K+ + G N + + L IQ ++ ++ IE + +I
Sbjct: 686 LKSSAAQIVAQRK------KLPKSGKNNTLTGSASLNAYIQRQEQYKQDEIERE-KIRME 738
Query: 81 FAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIE 140
E+ E +K++++ ++ +G+ ++LK+ E+ + R+ K E+R+
Sbjct: 739 MQRKREEIQRKQDEIRKMREETEKQHKKGE--ERLKQEEERFKKEEEERK--KKEEERLR 794
Query: 141 NLESENKKLKKDIQ-----------EEQAQRKIEIEGKLEKSNAFAALENEVSALKSENK 189
E ENK++K++ Q EE+ +RK+E E + K E E E
Sbjct: 795 QEEEENKRIKEERQRKEEELRKKKAEEERKRKLEEEARKRKEEEEQRKEEEEKRKVEEEL 854
Query: 190 KLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDR 249
K K+ EE+ +RK A+E K + LE E + E KK +++ E+ + + +R
Sbjct: 855 KKKE---EEERKRKEAIELKKK------QLEEERKKKEEERKKREEE---ERKKEEEEER 902
Query: 250 LKK----KCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLE 305
LK+ K K+ E R +A+K ++ E E ++ K++ E +RK E E K +
Sbjct: 903 LKQIEQEKQRKLEEERKKKEEAIKRKKEEEERKRKEEERRKRE--EAERKRKEEEERKRK 960
Query: 306 ISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSE 365
A +E E K E ++ KK EE+ QR++ E KL LE E L+ E
Sbjct: 961 EEEAKRKIEQERQR-KIEEERRKK---EEEEQRRLEEEKKL--------LEEEQKRLEEE 1008
Query: 366 NKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDI 425
+K +++ +A+ K ++ ++K K E R + K E+ + E +K KK++
Sbjct: 1009 ERKAEEERKRVEAERKRKEEEERK-RKEEEERKRKEEERKRKEEEERKRKEEEEKRKKEL 1067
Query: 426 QE-----EQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEE 480
+E E+ +RK E E K + E K+E+ + +K+ EE+ + K E
Sbjct: 1068 EELKKLKEEERRKKEEELKRK---------QEEEKRKAEAERKRKE--EEERKRKEEEER 1116
Query: 481 KLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKE 540
K + A E K + L++K A ++ + E K + K+ +K
Sbjct: 1117 KRKEEEKRKAEEER----KRKEEELRKKKEAEEKKRKLEEEHKKKE-EELRKKKEEEEKR 1171
Query: 541 LVEKEKIVADSERKTAVDERKKAAAEARKLL---EAAKKIAPEKAVIPEPANCCSKCDEL 597
E+EK A+ ERK +E K E ++ E KK E+ E K +E
Sbjct: 1172 RQEEEKRKAEEERKRKEEEEKARKEEEERIKREEEERKKQEEEERKKKEEEELRVKQEEE 1231
Query: 598 KKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAR 657
KKK + R + + E+ + E E ++LKKE E K + A +++ A
Sbjct: 1232 KKKRAEEEEKRRRAEERKRKEEEARKKEEEEVERLKKELEEEERKLK-EAEEERKRIEAE 1290
Query: 658 EGNGDVEVLKAGISDTKK--EVNRLKKEHVEEERIVADSERKTAVDER-KNAAAEARKLL 714
+ E K + +K E R +KE E+ R + +RK +ER + E RK
Sbjct: 1291 RKRKEEEKKKREEEEKRKREEEERKRKEEEEKARKEEEEKRKREDEERMRRHEEERRKWE 1350
Query: 715 EAPKKIAAEVEKQIAKVE-LRQVHLE-KQVNERKMKLAFELSKTKEATKRFEA 765
E K AE E+ + E LRQ K+ ER + A L K KE T+RF+A
Sbjct: 1351 EEQKARMAEFEEMKREAERLRQEAARLKEEEERLKQEAERLKKEKEETERFKA 1403
Score = 127 bits (318), Expect = 2e-27
Identities = 178/785 (22%), Positives = 343/785 (43%), Gaps = 129/785 (16%)
Query: 52 ENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKK-LKQDILEEQAQGK 110
+ ++ ++ Q+ +AQ+ ++ + +F + S + + K+ +KQ+ ++ +
Sbjct: 549 QRQRYLREQQDLEAQKTSVTRNVVKPTPSFKKSATQSSTIEEKQKEGMKQETNQQTEEVD 608
Query: 111 ICD----QLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIE-IE 165
+ Q ++ E+ + + A + K E ++ KDI + ++ I +
Sbjct: 609 LSKMTFVQRQRWEREQQDKRAEQTTAK--SHGYEAKFAKQTSTPKDIVYQDSREDINGVN 666
Query: 166 GKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRK-VAMEGKLEISNAFAALENEVS 224
+L++ N E +K + LK + AQRK + GK A+L +
Sbjct: 667 KELQQGN------EEDQCVKPSSMGLKSSAAQIVAQRKKLPKSGKNNTLTGSASL----N 716
Query: 225 ALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALR----QAVKILEKGIENLES 280
A ++ KQD ++ + K +++K E++ ++ +R + K +KG E L+
Sbjct: 717 AYIQRQEQYKQDEIERE---KIRMEMQRKREEIQRKQDEIRKMREETEKQHKKGEERLKQ 773
Query: 281 ENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDIL--EEQAQR 338
E ++ KK EE ++K E E + + ENK++K++ EE+ ++
Sbjct: 774 EEERFKK---EEEERKKKE--------------EERLRQEEEENKRIKEERQRKEEELRK 816
Query: 339 KVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRN 398
K A E + LE E K E ++ K EE+ + K ++LKKK E+ + +
Sbjct: 817 KKAEEERKR------KLEEEARKRKEEEEQRK----EEEEKRKVEEELKKKEEEERKRKE 866
Query: 399 ALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKS 458
A+ K LE+ + E E KK +EE+ ++K E E +L+ +E E
Sbjct: 867 AIELKKKQLEEERKKKEEERKK-----REEEERKKEEEEERLK------QIEQEKQRKLE 915
Query: 459 ESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNG 518
E K K++ ++ + + EE+ + E K E A ++K
Sbjct: 916 EERKKKEEAIKRKKE-----EEERK--------RKEEERRKREEAERKRK---------- 952
Query: 519 DVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIA 578
+ E K + ++++ ++ +E+E+ + E + ++E KK E +K LE ++ A
Sbjct: 953 EEEERKRKEEEAKRKIEQERQRKIEEERRKKEEEEQRRLEEEKKLLEEEQKRLEEEERKA 1012
Query: 579 PEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEV 638
E+ E + +E K+K E+ + R+ + E+ + E E K+ K+ E+
Sbjct: 1013 EEERKRVEAERKRKEEEERKRKEEEERKRKEEERKRKEEEER--KRKEEEEKRKKELEEL 1070
Query: 639 SALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKT 698
LK E + +K+ LK++ EE+R ++
Sbjct: 1071 KKLKEE---------------------------ERRKKEEELKRKQEEEKRKAEAERKRK 1103
Query: 699 AVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKE 758
+ERK E RK E K+ AE E++ + ELR+ +K+ E+K KL E K +E
Sbjct: 1104 EEEERKRKEEEERKRKEEEKR-KAEEERKRKEEELRK---KKEAEEKKRKLEEEHKKKEE 1159
Query: 759 AT--KRFEAEKKKLLVEKINAESKIKKAQE-----RSESELDKKTADMEKQQAEEQKKLA 811
K+ E EK++ EK AE + K+ +E + E E K+ + K+Q EE++K
Sbjct: 1160 ELRKKKEEEEKRRQEEEKRKAEEERKRKEEEEKARKEEEERIKREEEERKKQEEEERKKK 1219
Query: 812 EDKLL 816
E++ L
Sbjct: 1220 EEEEL 1224
Score = 124 bits (312), Expect = 1e-26
Identities = 153/630 (24%), Positives = 281/630 (44%), Gaps = 96/630 (15%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEIS 78
EELKKK E+ + A+ K LE+ + E E KK +EE+ ++K E +L+
Sbjct: 852 EELKKKEEEERKRKEAIELKKKQLEEERKKKEEERKK-----REEEERKKEEEEERLK-- 904
Query: 79 NTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKR 138
+E E + E +K K++ ++ + + ++ K+ E+ R + K E+R
Sbjct: 905 ----QIEQEKQRKLEEERKKKEEAIKRKKEE---EERKRKEEERRKREEAERKRKEEEER 957
Query: 139 IENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEE 198
E +K+ E++ QRKIE E + ++ LE E L+ E K+L+++ +
Sbjct: 958 KRKEEEAKRKI-----EQERQRKIEEERRKKEEEEQRRLEEEKKLLEEEQKRLEEEERKA 1012
Query: 199 QAQRK-VAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKV 257
+ +RK V E K + E E K E +K K++ +E+ + + ++ KK+ E++
Sbjct: 1013 EEERKRVEAERKRKEEEERKRKEEEERKRKEEERKRKEE--EERKRKEEEEKRKKELEEL 1070
Query: 258 VEGRNALRQAVKILEKGIENLESENKKL----KKDIQEEHAQRKVEIEGKLEISNAFAAL 313
+ + R+ E+ ++ + E K+ +K +EE +RK E E K
Sbjct: 1071 KKLKEEERRK---KEEELKRKQEEEKRKAEAERKRKEEEERKRKEEEERK---------- 1117
Query: 314 ENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDI 373
E K+E ++ +K+ EE ++K A E K ++ E E+ K E +K +Q+
Sbjct: 1118 RKEEEKRKAEEERKRKE--EELRKKKEAEEKKRKLEEEHKKKEEELRKKKEEEEKRRQE- 1174
Query: 374 LEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKD-----IQEE 428
EE+ + ++ +K+ E+ + R + +K E+ + E E +K K++ QEE
Sbjct: 1175 -EEKRK---AEEERKRKEEEEKARKEEEERIKREEEERKKQEEEERKKKEEEELRVKQEE 1230
Query: 429 QAQRKIEIEGKLEISNAFAALENEVSALKSEST-KLKKDILEEQAQIKVAIEEKLEISNA 487
+ +++ E E K + E E + E +LKK++ EE+ ++K A EE+ I
Sbjct: 1231 EKKKRAEEEEKRRRAEERKRKEEEARKKEEEEVERLKKELEEEERKLKEAEEERKRIEAE 1290
Query: 488 FAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKI 547
E E + E E K +E +KE EK +
Sbjct: 1291 RKRKEEEKKKREEE-------------------EKRK------REEEERKRKEEEEKARK 1325
Query: 548 VADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVG 607
+ +RK +ER + E R+ E +K ++ +E+K++ E+
Sbjct: 1326 EEEEKRKREDEERMRRHEEERRKWEEEQKAR------------MAEFEEMKREAER---- 1369
Query: 608 RNALRQAVKILEKGIENLESENKKLKKENE 637
LRQ L++ E L+ E ++LKKE E
Sbjct: 1370 ---LRQEAARLKEEEERLKQEAERLKKEKE 1396
Score = 115 bits (287), Expect = 8e-24
Identities = 167/720 (23%), Positives = 321/720 (44%), Gaps = 71/720 (9%)
Query: 126 NALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALK 185
+ +++ +K + + N+E K + + Q +Q K+ + K +++ + N K
Sbjct: 483 STVQETIKSPKTQQPNIE---KPIVSNHQSTASQPKLLVNLKSSPTSSSPSNTNNSDKEK 539
Query: 186 SENKKL----KKDILEEQ----AQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDI 237
+ K+ ++ L EQ AQ+ ++ + +F + S ++ + K+ +
Sbjct: 540 VDLSKMSFVQRQRYLREQQDLEAQKTSVTRNVVKPTPSFKKSATQSSTIEEKQKEGMKQE 599
Query: 238 LDEQAQGKFCDRL----KKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEH 293
++Q + ++ +++ E+ + + A + K G E ++ KDI +
Sbjct: 600 TNQQTEEVDLSKMTFVQRQRWEREQQDKRAEQTTAK--SHGYEAKFAKQTSTPKDIVYQD 657
Query: 294 AQRKVE-IEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRK-VAMEGKLEISNA 351
++ + + +L+ N E +K + LK + AQRK + GK
Sbjct: 658 SREDINGVNKELQQGN------EEDQCVKPSSMGLKSSAAQIVAQRKKLPKSGKNNTLTG 711
Query: 352 FAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALR----QAVKIL 407
A+L +A ++ KQD +E + K ++++K E++ ++ +R + K
Sbjct: 712 SASL----NAYIQRQEQYKQDEIERE---KIRMEMQRKREEIQRKQDEIRKMREETEKQH 764
Query: 408 EKGIENLESENKKLKKDIQE----EQAQRKIEIEGKLEISNAFAALENEVSALKSESTKL 463
+KG E L+ E ++ KK+ +E E+ + + E E I E E+ K+E +
Sbjct: 765 KKGEERLKQEEERFKKEEEERKKKEEERLRQEEEENKRIKEERQRKEEELRKKKAEEERK 824
Query: 464 KKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVL 523
+K LEE+A+ + EE+ + +E E+ K E ++K ++ + E
Sbjct: 825 RK--LEEEARKRKEEEEQRKEEEEKRKVEEELK--KKEEEERKRKEAIELKKKQLEEERK 880
Query: 524 KAGISDTEKEVNTLKKELVEK--EKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEK 581
K ++E KKE E+ ++I + +RK + +KK A RK E +K E+
Sbjct: 881 KKEEERKKREEEERKKEEEEERLKQIEQEKQRKLEEERKKKEEAIKRKKEEEERKRKEEE 940
Query: 582 AVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSAL 641
E A K +E +K+ E+ A + + KI E+ + E E ++L++E ++ L
Sbjct: 941 RRKREEAERKRKEEEERKRKEEEAKRKIEQERQRKIEEERRKKEEEEQRRLEEEKKL--L 998
Query: 642 KSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVD 701
+ E L++ E KA + E R +KE E +R + ERK +
Sbjct: 999 EEEQKRLEE-------------EERKAEEERKRVEAERKRKEEEERKR-KEEEERKRKEE 1044
Query: 702 ERKNAAAEARKLLEAPKKIAAEVE--KQIAKVELRQVHLE---KQVNERKMKLAFELSKT 756
ERK E RK E +K E+E K++ + E R+ E KQ E++ A K
Sbjct: 1045 ERKRKEEEERKRKEEEEKRKKELEELKKLKEEERRKKEEELKRKQEEEKRKAEAERKRKE 1104
Query: 757 KEATKRFEAEKKKLLVEKINAESKIKKAQERSESEL-DKKTADMEKQQAEEQKKLAEDKL 815
+E KR E E++K K + K ++ ++R E EL KK A+ +K++ EE+ K E++L
Sbjct: 1105 EEERKRKEEEERK---RKEEEKRKAEEERKRKEEELRKKKEAEEKKRKLEEEHKKKEEEL 1161
Score = 86.3 bits (212), Expect = 4e-15
Identities = 144/680 (21%), Positives = 290/680 (42%), Gaps = 68/680 (10%)
Query: 170 KSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGK---LEISNAFAALENEVSAL 226
KS + EN+VS N + I + Q ++ + L S+ +A + + +
Sbjct: 355 KSPTSSLNENKVSTGSHINSTISSPIKQTQPTTSQTLQTRKQSLTPSHQISAEQMKQPLV 414
Query: 227 KSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLK 286
K+ KQ + + R+ K E ++ + +N+ + K
Sbjct: 415 KTSTNTQKQQPSISKQESFSSQRVAKSPEPTLKDMS-------------QNVSKSTEPAK 461
Query: 287 KDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKL 346
+ + Q++ I K S+ ++ + + K++ ++K I+ + A + KL
Sbjct: 462 TNTTVKGIQKQSNIPVKETESST---VQETIKSPKTQQPNIEKPIVSNH--QSTASQPKL 516
Query: 347 EISNAFAALENEVSALKSENKKLKQDILEE---QAQGKFCDQLKKKCEKVVEGRNALR-- 401
++ + + S + +K+ K D+ + Q Q +Q + +K RN ++
Sbjct: 517 LVNLKSSPTSSSPSNTNNSDKE-KVDLSKMSFVQRQRYLREQQDLEAQKTSVTRNVVKPT 575
Query: 402 --------QAVKILEKGIENLESENKKLKKDIQEEQA----QRKIEIEGKLEISNAFAAL 449
Q+ I EK E ++ E + +++ + +++ E E + + + A
Sbjct: 576 PSFKKSATQSSTIEEKQKEGMKQETNQQTEEVDLSKMTFVQRQRWEREQQDKRAEQTTAK 635
Query: 450 ENEVSALKSESTKLKKDILEEQAQIKV-AIEEKLEISNAF-AALENEVSALKSEIAALQQ 507
+ A ++ T KDI+ + ++ + + ++L+ N ++ LKS A +
Sbjct: 636 SHGYEAKFAKQTSTPKDIVYQDSREDINGVNKELQQGNEEDQCVKPSSMGLKSSAAQIVA 695
Query: 508 KCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEA 567
+ + G + A ++ + K++ +E+EKI + +RK +RK+ E
Sbjct: 696 QRKKLPKSGKNNTLTGSASLNAYIQRQEQYKQDEIEREKIRMEMQRKREEIQRKQD--EI 753
Query: 568 RKLLEAAKKIAP--EKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENL 625
RK+ E +K E+ + E + +E KKK E+ ++ ++ EN
Sbjct: 754 RKMREETEKQHKKGEERLKQEEERFKKEEEERKKKEEE------------RLRQEEEENK 801
Query: 626 ESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHV 685
+ ++ +KE E+ K+E ++K AR+ + E K K E KKE
Sbjct: 802 RIKEERQRKEEELRKKKAE-EERKRKLEEEARKRKEEEEQRKEEEEKRKVEEELKKKEEE 860
Query: 686 EEERIVA-DSERKTAVDERKNAAAEARKLLEAPKKIAAEVE--KQIAKVELRQVHLEKQV 742
E +R A + ++K +ERK E +K E +K E E KQI + + R++ E++
Sbjct: 861 ERKRKEAIELKKKQLEEERKKKEEERKKREEEERKKEEEEERLKQIEQEKQRKLEEERKK 920
Query: 743 NERKMKLAFELSKTK----EATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKK-TA 797
E +K E + K E KR EAE+K+ E+ + K ++A+ + E E +K
Sbjct: 921 KEEAIKRKKEEEERKRKEEERRKREEAERKR--KEEEERKRKEEEAKRKIEQERQRKIEE 978
Query: 798 DMEKQQAEEQKKLAEDKLLL 817
+ K++ EEQ++L E+K LL
Sbjct: 979 ERRKKEEEEQRRLEEEKKLL 998
Score = 48.1 bits (113), Expect = 0.001
Identities = 52/188 (27%), Positives = 87/188 (45%), Gaps = 21/188 (11%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEIS 78
EE KK+ E+ R A + K E+ + E E ++LKK+++EE+ + K A E + I
Sbjct: 1230 EEKKKRAEEEEKRRRAEERKRKE-EEARKKEEEEVERLKKELEEEERKLKEAEEERKRIE 1288
Query: 79 NTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKR 138
E E E K+ ++ EE+ + K ++ +K K E + E+R
Sbjct: 1289 AERKRKEEEKKKREEEEKRKRE---EEERKRK--EEEEKARKEEEEKRKRED-----EER 1338
Query: 139 IENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAF----AALENEVSALKSENKKLKKD 194
+ E E +K +EEQ R E E ++ A L+ E LK E ++LKK+
Sbjct: 1339 MRRHEEERRKW----EEEQKARMAEFEEMKREAERLRQEAARLKEEEERLKQEAERLKKE 1394
Query: 195 ILEEQAQR 202
+E+ +R
Sbjct: 1395 --KEETER 1400
>gb|AAB48065.1| myosin heavy chain [Entamoeba histolytica] gi|7494129|pir||T18296
myosin heavy chain - Entamoeba histolytica
Length = 2139
Score = 154 bits (389), Expect = 1e-35
Identities = 194/824 (23%), Positives = 367/824 (43%), Gaps = 111/824 (13%)
Query: 48 NLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQA 107
N E E KK K+I E ++K+A E K A EN +++ ++ +L+ I + +
Sbjct: 858 NFEEEGKKKDKEI--EDLKKKLAEEIKKR-----EAAENALASATAKTGELEAKIQDLE- 909
Query: 108 QGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGK 167
D++ + E + +Q + + +IENLE + ++LK+ I + K + K
Sbjct: 910 -----DKISELESKLSAAELDKQELNL---KIENLEEDKEELKETIDNLKGDLK---DSK 958
Query: 168 LEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALK 227
L+ + LE E++ L S+ L + ++ E E + L+ ++ L+
Sbjct: 959 LKGED----LEVEITELNSQINTLNATVDKKDKTIAEMQESIDEKEDEITKLKGDIKLLE 1014
Query: 228 SENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKK 287
E L+QD D A D + KK K+ + + LE+ +E+ E++NK L
Sbjct: 1015 EEKDDLEQDRADVSATK---DDIAKKLNKITIECEDAKDEIAKLEQELEDEENKNKDLTN 1071
Query: 288 DIQEEHAQRKVEIEGKLEISNAFAALENEVSALK---SENKKLKKDILEEQAQRKVAMEG 344
++Q+ +L++ +L +V+A K E L +++ E+ K +
Sbjct: 1072 ELQQT----------QLKLGETEKSLAAQVAATKKASDERDTLSQNLENEKLTTKNLTKT 1121
Query: 345 KLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQ-----------LKKKCE-- 391
K ++ + L+ + L+ + K++ D+ Q + K D L+K+ E
Sbjct: 1122 KADLEKKISGLKQDYEDLEDDKNKIEGDLRNAQRKIKELDDEITKGADVSQYLQKQKEEY 1181
Query: 392 -----KVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAF 446
K+ E + A+ VK EK I+ E E + L++ + E + +++ + K EI
Sbjct: 1182 ESQIAKMQEEKEAIGNDVKNKEKTIKEKELEIQSLQEKLDETEVEKEDAEKKKKEIEKEM 1241
Query: 447 AALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENE-VSALKSEIAAL 505
AL+ E ++S +KD + + +K ++KL+ A +NE + A ++ A
Sbjct: 1242 KALQEEKENVESSKNSTEKDKKKLEDNLK-DTQKKLDDMTA----DNEKLKAKAKDLEAQ 1296
Query: 506 QQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKEL--VEKEKIVADSERKTAVDER--- 560
+ + D E+L + ++KE+N+LK EL + K K V +S+ K + +E+
Sbjct: 1297 LNEVQDNHEKAVADAELLNKKKAQSDKELNSLKAELEALTKAKSVVESKNKDSENEKAAL 1356
Query: 561 -----------KKAAAEARK----LLEAAKKIAPEKA----VIPEPANCCSKCDELKKKC 601
K A+ RK L EA +K A +A ++ + +E+K +
Sbjct: 1357 SEEIDQANEKLKNIQADLRKATADLQEANEKKAEVEAQRDKLVADNKKMTKTLEEIKARD 1416
Query: 602 E----KVAVGRNALRQAVKILEKGIENLESENK-KLKKENEVSALKSEISALQQKCGAGA 656
E KV L++ LE+ ENL+ E K ++ KE +V L+ E+ + K A
Sbjct: 1417 EENTYKVENYEKVLKRKEADLEEANENLDIEKKDRMNKEKQVKKLEGELKETKDKLNAAI 1476
Query: 657 REGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAA-----EAR 711
E + K +D +E+N+ +EH + +VA + R N +A E R
Sbjct: 1477 AEKDSIFTAKKQSDADL-EELNKTVEEH---DEVVAKLNTQITKLTRDNQSAEEELNELR 1532
Query: 712 KLLEAPKKIAAEVEKQIAKVELRQVHL----EKQVNERKMKLAFELSKTKE----ATKRF 763
+ KK +E+E+Q+ ++E R V E ++ R ++A +L+K E +
Sbjct: 1533 SKADKDKKKISELEEQVNELESRPVGTGNADENEIKIRDAQIA-DLNKALEMKGVQNNQL 1591
Query: 764 EAEKKKLLVEKINAESKIKKAQ-ERSESELDKKTADMEKQQAEE 806
+A K+L + + SKI+ + E + E KK + +K +A++
Sbjct: 1592 QATNKELKAKDNDLTSKIEITENEMKKLENAKKRLEQDKDEADK 1635
Score = 140 bits (353), Expect = 2e-31
Identities = 163/710 (22%), Positives = 323/710 (44%), Gaps = 73/710 (10%)
Query: 130 QAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENK 189
+A +L++R N E E KK K+I++ + + EI+ + NA A+ + L+++ +
Sbjct: 849 KARPMLKRR--NFEEEGKKKDKEIEDLKKKLAEEIKKREAAENALASATAKTGELEAKIQ 906
Query: 190 KLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDR 249
L+ I E +++ A K E++ LE + LK LK D+ D + +G
Sbjct: 907 DLEDKISELESKLSAAELDKQELNLKIENLEEDKEELKETIDNLKGDLKDSKLKG----- 961
Query: 250 LKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNA 309
E+LE E +L I +A + + E+ +
Sbjct: 962 --------------------------EDLEVEITELNSQINTLNATVDKKDKTIAEMQES 995
Query: 310 FAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKL 369
E+E++ LK + K L+++ + + R K +I+ + E K E KL
Sbjct: 996 IDEKEDEITKLKGDIKLLEEEKDDLEQDRADVSATKDDIAKKLNKITIECEDAKDEIAKL 1055
Query: 370 KQDILEEQAQGK-FCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEE 428
+Q++ +E+ + K ++L++ K+ E +L V +K E L ++++ E
Sbjct: 1056 EQELEDEENKNKDLTNELQQTQLKLGETEKSLAAQVAATKKA----SDERDTLSQNLENE 1111
Query: 429 QAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAF 488
+ K + K ++ + L+ + L+ + K++ D+ Q +IK +E + ++
Sbjct: 1112 KLTTKNLTKTKADLEKKISGLKQDYEDLEDDKNKIEGDLRNAQRKIKELDDEITKGADVS 1171
Query: 489 AALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIV 548
L+ + +S+IA +Q++ A GN DV+ + I + E E+ +L+++L E E
Sbjct: 1172 QYLQKQKEEYESQIAKMQEEKEA---IGN-DVKNKEKTIKEKELEIQSLQEKLDETEVEK 1227
Query: 549 ADSE-RKTAVDERKKAAAEARKLLEAAKKIA--PEKAVIPEPANCCSKCDELKKKCEKVA 605
D+E +K +++ KA E ++ +E++K +K + + K D++ EK+
Sbjct: 1228 EDAEKKKKEIEKEMKALQEEKENVESSKNSTEKDKKKLEDNLKDTQKKLDDMTADNEKLK 1287
Query: 606 VGRNALRQAVKIL----EKGIENLESEN-KKLKKENEVSALKSEISALQQKCGAGAREGN 660
L + + EK + + E N KK + + E+++LK+E+ AL K + N
Sbjct: 1288 AKAKDLEAQLNEVQDNHEKAVADAELLNKKKAQSDKELNSLKAELEAL-TKAKSVVESKN 1346
Query: 661 GDVEVLKAGISDTKKEVN-RLKKEHVEEERIVAD----SERKTAVD-ERKNAAAEARKLL 714
D E KA +S+ + N +LK + + AD +E+K V+ +R A+ +K+
Sbjct: 1347 KDSENEKAALSEEIDQANEKLKNIQADLRKATADLQEANEKKAEVEAQRDKLVADNKKMT 1406
Query: 715 EAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEK 774
+ ++I A E+ KVE + EK + ++ L +EA + + EKK ++
Sbjct: 1407 KTLEEIKARDEENTYKVE----NYEKVLKRKEADL-------EEANENLDIEKK----DR 1451
Query: 775 INAESKIKKAQERSESELDKKTADM-EKQQAEEQKKLAEDKLLLLGDSLQ 823
+N E ++KK + + DK A + EK KK ++ L L +++
Sbjct: 1452 MNKEKQVKKLEGELKETKDKLNAAIAEKDSIFTAKKQSDADLEELNKTVE 1501
Score = 136 bits (342), Expect = 3e-30
Identities = 189/835 (22%), Positives = 361/835 (42%), Gaps = 116/835 (13%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEIS 78
EE + + ++ + A+ VK EK I+ E E + L++ + E + +++ A + K EI
Sbjct: 1179 EEYESQIAKMQEEKEAIGNDVKNKEKTIKEKELEIQSLQEKLDETEVEKEDAEKKKKEIE 1238
Query: 79 NTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKR 138
AL+ E + S ++D + L +K +K+
Sbjct: 1239 KEMKALQEEKENVESSKNSTEKD-----------------------KKKLEDNLKDTQKK 1275
Query: 139 IENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEE 198
++++ ++N+KLK ++ +AQ E++ EK+ A A L N+ A + K LE
Sbjct: 1276 LDDMTADNEKLKAKAKDLEAQLN-EVQDNHEKAVADAELLNKKKAQSDKELNSLKAELEA 1334
Query: 199 QAQRKVAMEGKLEIS-NAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCE-- 255
+ K +E K + S N AAL E+ + K ++ D+ A + + K + E
Sbjct: 1335 LTKAKSVVESKNKDSENEKAALSEEIDQANEKLKNIQADLRKATADLQEANEKKAEVEAQ 1394
Query: 256 --KVVEGRNALRQAVKILEKG-------IENLESENKKLKKDIQEEHAQRKVEIEGKLEI 306
K+V + + ++ ++ +EN E K+ + D++E + +E + ++
Sbjct: 1395 RDKLVADNKKMTKTLEEIKARDEENTYKVENYEKVLKRKEADLEEANENLDIEKKDRMNK 1454
Query: 307 SNAFAALENEVSALKSENKKLKKDILEEQA--QRKVAMEGKLEISN--------AFAALE 356
LE E LK KL I E+ + K + LE N A L
Sbjct: 1455 EKQVKKLEGE---LKETKDKLNAAIAEKDSIFTAKKQSDADLEELNKTVEEHDEVVAKLN 1511
Query: 357 NEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQA-----------VK 405
+++ L +N+ ++++ E +++ D+ KKK ++ E N L +K
Sbjct: 1512 TQITKLTRDNQSAEEELNELRSKA---DKDKKKISELEEQVNELESRPVGTGNADENEIK 1568
Query: 406 ILEKGIENLESENKKLK-KDIQEEQAQR-KIEIEGK-LEISNAFAALENEVSALKSESTK 462
I + I +L NK L+ K +Q Q Q E++ K ++++ ENE+ L++ +
Sbjct: 1569 IRDAQIADL---NKALEMKGVQNNQLQATNKELKAKDNDLTSKIEITENEMKKLENAKKR 1625
Query: 463 LKKDILE-EQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVE 521
L++D E ++A + I+ K LE EV L +EI AL+ + A S + +
Sbjct: 1626 LEQDKDEADKAVSEQTIKRK--------GLEEEVKKLTTEIQALKFQINAPSSVAQEEEK 1677
Query: 522 VLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEK 581
E ++ LK++L ++ A++E ERKK AE ++ + + ++
Sbjct: 1678 ------QRLESDIAELKEQLEQERTTAANAEA-----ERKKIQAELDEVKFNLEDVTNQR 1726
Query: 582 AVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSAL 641
++L K + ++L++ K LE IE + +N KL +E
Sbjct: 1727 -------------EKLVAKNSENDAEIDSLKEEKKALEDEIEKITDDNNKLSEE------ 1767
Query: 642 KSEISALQQKCGAGAREGNGDV---EVLKAGISDTKKEVNRLKKEHVEEERIVADSERKT 698
I +L +K A + DV E + + TK + KK H E R+ E++
Sbjct: 1768 ---IDSLDRKYNALLDSKDSDVSMKEKFQDELKVTKDALETEKKNHAETMRLKGRLEKEA 1824
Query: 699 AVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLE-KQVNERKMKLAFELSKTK 757
A + + A + L +K A + + A EL+ + E V ++ K +L+ +
Sbjct: 1825 AEVQVRLEALQKNLDLAQQEKAKATKDYRAADGELKSLMNELDDVKDQLDKAQDDLADKE 1884
Query: 758 EATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAE 812
+ + + K L+ +K +S+I++ QE+ + E + A +KQ+ +KKL E
Sbjct: 1885 DELATLDQKYKTLVKQKSVFDSRIQEMQEQLDLEKAGR-AKAQKQKQAYEKKLQE 1938
Score = 128 bits (321), Expect = 9e-28
Identities = 188/875 (21%), Positives = 386/875 (43%), Gaps = 117/875 (13%)
Query: 17 KCEELKKKCEQVVVGRNALRQAVKILEKGIENLES---ENKKLKKDIQEEQAQRKVAIEG 73
K +E + + E + + + +K L++ EN+ES +K KK +++ + ++
Sbjct: 1219 KLDETEVEKEDAEKKKKEIEKEMKALQEEKENVESSKNSTEKDKKKLEDNLKDTQKKLDD 1278
Query: 74 KLEISNTFAALENEVSALISE---------------NKKLKQDILEEQAQGKICDQLKKC 118
+ A ++ A ++E NKK Q E + + L K
Sbjct: 1279 MTADNEKLKAKAKDLEAQLNEVQDNHEKAVADAELLNKKKAQSDKELNSLKAELEALTKA 1338
Query: 119 EKVVEGRN--------ALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEK 170
+ VVE +N AL + + ++++N++++ +K D+QE ++K E+E + +K
Sbjct: 1339 KSVVESKNKDSENEKAALSEEIDQANEKLKNIQADLRKATADLQEAN-EKKAEVEAQRDK 1397
Query: 171 SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSEN 230
L ++NKK+ K + E +A+ + E ++ N L+ + + L+ N
Sbjct: 1398 -------------LVADNKKMTKTLEEIKARDE---ENTYKVENYEKVLKRKEADLEEAN 1441
Query: 231 KKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQ 290
+ L + D + K +L+ + ++ + NA + + +++ ++L K +
Sbjct: 1442 ENLDIEKKDRMNKEKQVKKLEGELKETKDKLNAAIAEKDSIFTAKKQSDADLEELNKTV- 1500
Query: 291 EEHAQRKVEIEGKL-EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEIS 349
EEH + ++ ++ +++ + E E++ L+S+ K KK I E + Q +
Sbjct: 1501 EEHDEVVAKLNTQITKLTRDNQSAEEELNELRSKADKDKKKISELEEQVNELESRPVGTG 1560
Query: 350 NAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEK 409
NA ENE+ ++ L + + + +G +QL+ +++ N L ++I E
Sbjct: 1561 NAD---ENEIKIRDAQIADLNKAL---EMKGVQNNQLQATNKELKAKDNDLTSKIEITEN 1614
Query: 410 GIENLESENKKLKKD-------IQEEQAQRKIEIEGKLEISNAFAALENEVSALKS---- 458
++ LE+ K+L++D + E+ +RK E +++ AL+ +++A S
Sbjct: 1615 EMKKLENAKKRLEQDKDEADKAVSEQTIKRKGLEEEVKKLTTEIQALKFQINAPSSVAQE 1674
Query: 459 -ESTKLKKDILEEQAQIKVAIEEKLEISNAFA------ALENEVSALKSEIAALQQKCGA 511
E +L+ DI E + Q++ +E+ +NA A A +EV ++ ++K A
Sbjct: 1675 EEKQRLESDIAELKEQLE---QERTTAANAEAERKKIQAELDEVKFNLEDVTNQREKLVA 1731
Query: 512 GSREGNGDVEVLKAGISDTEKEV-------NTLKKE-----------LVEKEKIVADSER 553
+ E + +++ LK E E+ N L +E L K+ V+ E+
Sbjct: 1732 KNSENDAEIDSLKEEKKALEDEIEKITDDNNKLSEEIDSLDRKYNALLDSKDSDVSMKEK 1791
Query: 554 --------KTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVA 605
K A++ KK AE +L +K A E V E D +++ K
Sbjct: 1792 FQDELKVTKDALETEKKNHAETMRLKGRLEKEAAEVQVRLEALQ--KNLDLAQQEKAKAT 1849
Query: 606 VGRNALRQAVKILEKGIENLESENKKLK-----KENEVSALKSEISAL-QQKCGAGAR-- 657
A +K L +++++ + K + KE+E++ L + L +QK +R
Sbjct: 1850 KDYRAADGELKSLMNELDDVKDQLDKAQDDLADKEDELATLDQKYKTLVKQKSVFDSRIQ 1909
Query: 658 EGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVAD-SERKTAVDERKNAAA----EARK 712
E +++ KAG + +K+ +K+ E + D E K D+R N + + +K
Sbjct: 1910 EMQEQLDLEKAGRAKAQKQKQAYEKKLQELQENDNDFEEYKETADKRINTLSAQKDDLQK 1969
Query: 713 LLEAPKKIAAEVEKQIAKVELRQVHLEKQVNE---RKMKLAFELSKTKEATKRFEAEKKK 769
LE + + + EK++ ++ ++ LE +V E + +A +K + + E +
Sbjct: 1970 ELEKERGLKQDSEKEVQRLRVKCQELETKVAEVGGANVSIAKVKAKYEAEIEELTTEAED 2029
Query: 770 LLVEKINAESKIKKAQERSESELDKKTADMEKQQA 804
L K+ AE K K +Q++ + EL K AD E ++A
Sbjct: 2030 ALKAKMKAEKKAKTSQKKLD-ELQKTIADYETKEA 2063
Score = 99.8 bits (247), Expect = 3e-19
Identities = 163/648 (25%), Positives = 278/648 (42%), Gaps = 94/648 (14%)
Query: 16 SKCEELKKKCEQVVVGR-NALRQAVKILEKGIENLESENKKLK-KDIQEEQAQ--RKVAI 71
S+ EE + E VG NA +KI + I +L NK L+ K +Q Q Q K
Sbjct: 1543 SELEEQVNELESRPVGTGNADENEIKIRDAQIADL---NKALEMKGVQNNQLQATNKELK 1599
Query: 72 EGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQA 131
++++ ENE+ L + K+L+QD +++A + +Q K R L +
Sbjct: 1600 AKDNDLTSKIEITENEMKKLENAKKRLEQD--KDEADKAVSEQTIK-------RKGLEEE 1650
Query: 132 VKILEKRIENLESENKKLKKDIQEEQAQRK----IEIEGKLEKSNAFAA-LENEVSALKS 186
VK L I+ L+ + QEE+ QR E++ +LE+ AA E E +++
Sbjct: 1651 VKKLTTEIQALKFQINAPSSVAQEEEKQRLESDIAELKEQLEQERTTAANAEAERKKIQA 1710
Query: 187 ENKKLKKDILEEQAQRKVAMEGKLE-------ISNAFAALENEVSALKSENKKLKQDILD 239
E ++K ++ + QR+ + E + ALE+E+ + +N KL ++I
Sbjct: 1711 ELDEVKFNLEDVTNQREKLVAKNSENDAEIDSLKEEKKALEDEIEKITDDNNKLSEEI-- 1768
Query: 240 EQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLE---SENKKLKKDIQEEHAQR 296
+ K+ L K + V + + +K+ + +E + +E +LK +++E A+
Sbjct: 1769 DSLDRKYNALLDSK-DSDVSMKEKFQDELKVTKDALETEKKNHAETMRLKGRLEKEAAEV 1827
Query: 297 KVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALE 356
+V +E AL+ + + E K KD A +G+L+ +L
Sbjct: 1828 QVRLE----------ALQKNLDLAQQEKAKATKDYR--------AADGELK------SLM 1863
Query: 357 NEVSALKSENKKLKQDILEEQAQGKFCDQLKK---KCEKVVEGRNALRQAVKILEK-GIE 412
NE+ +K + K + D+ +++ + DQ K K + V + R Q LEK G
Sbjct: 1864 NELDDVKDQLDKAQDDLADKEDELATLDQKYKTLVKQKSVFDSRIQEMQEQLDLEKAGRA 1923
Query: 413 NLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTK---LKKDILE 469
+ + + +K +QE Q E K L + L+ E K LK+D +
Sbjct: 1924 KAQKQKQAYEKKLQELQENDNDFEEYKETADKRINTLSAQKDDLQKELEKERGLKQDSEK 1983
Query: 470 EQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISD 529
E +++V +E LE A EV IA ++ K A E + E
Sbjct: 1984 EVQRLRVKCQE-LETKVA------EVGGANVSIAKVKAKYEAEIEELTTEAEDALKAKMK 2036
Query: 530 TEKEVNTLKKELVEKEKIVADSERKTAV--DERKKAAAEARKLLEAAKKIAPEKAVIPEP 587
EK+ T +K+L E +K +AD E K A E K AE +K ++ V +
Sbjct: 2037 AEKKAKTSQKKLDELQKTIADYETKEASFNTEIGKTQAELKKY---------QQQVRDDE 2087
Query: 588 ANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKE 635
S DE+KK G +AL A K LE ++ + + +KLKK+
Sbjct: 2088 TRMSSLEDEIKK-------GTDAL--ANKQLE--LDKVNKQYEKLKKQ 2124
>emb|CAG77705.1| unnamed protein product [Yarrowia lipolytica CLIB99]
gi|50554989|ref|XP_504903.1| hypothetical protein
[Yarrowia lipolytica]
Length = 1906
Score = 153 bits (386), Expect = 3e-35
Identities = 218/866 (25%), Positives = 376/866 (43%), Gaps = 104/866 (12%)
Query: 4 EKAVIPEPANCCSKCEELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDI--- 60
EK++ A S E +K Q+ + +K L++ + +E KLK D+
Sbjct: 1013 EKSLSAAEAQSKSVAAEKEKVSGQIATHE----ETIKRLKEELSERTAELDKLKSDLASS 1068
Query: 61 QEEQAQRKVAIEGK----------LEISNT-FAALENEVSALISENKKLKQDILEEQA-- 107
+++ A + + K LE +N+ A+ EV L SE K K D + +
Sbjct: 1069 EKDLASKTKDVSAKDTEIEKLKSELETANSKLASTAKEVEILTSELKAAKSDACDSETKI 1128
Query: 108 ---QGKICDQLKKCE-----------KVVEGRNALRQAVKILEKRIENLESENKKLKKDI 153
+ ++ +Q K E V G L + V ++E LES++K+L
Sbjct: 1129 KAVESELVEQKSKVEHLNAELAAKSSSVESGAAELAEKVALVESLTAKLESKDKELATKT 1188
Query: 154 QEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEIS 213
+E A+ K E+E K + LE + + L +++K+L ++A A +LE S
Sbjct: 1189 EELSAKEK-ELETKTSE------LETKTAELTTKSKELTAK--SDEATTYSAKVKELETS 1239
Query: 214 NAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEK 273
+A ALE + + LK+ L +D+ ++ + L ++ + ++ V +L K
Sbjct: 1240 SA--ALEKKQTTLKAMADNLTKDLAEKTKE------LVAAKSELESSNTSSKEEVDVLTK 1291
Query: 274 GIENLESENKKLKKDIQ--EEHAQRKVE-IEGKL----EISNAFAALENEVSALKSENKK 326
+ + +E +LKK Q E A KV +E KL E S A N++ + E +
Sbjct: 1292 KLSDATAEAVELKKSSQAAETEASSKVSALEAKLTKASESSKAELDKVNKLLSSFKEKLQ 1351
Query: 327 LKKDI-------LEEQAQRKVAMEGKLE-----ISNAFAALENEVSALKSE-NKKLKQDI 373
KD L EQ + E + + A E E AL++E + +K+
Sbjct: 1352 TSKDDHSTEVSKLTEQVRESTLKAENFEHDISSLKDDLAQAEKERDALRTELDTSIKEME 1411
Query: 374 LEEQAQGKFCDQLKKKC-EKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQR 432
E + K D K+ KV + L + +K + + E+E K LKK+I+ QA+
Sbjct: 1412 NERTSLTKDADSATKELTNKVSMLQTKLDELTASHKKALGDSETEAKGLKKEIKAAQAEI 1471
Query: 433 KI--EIEGKLEISNA-FAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKL-EISNAF 488
K E++ K E S LE +VS L +ES + K E +K A+EEKL E S+A
Sbjct: 1472 KTLEEVKAKYEASQTDIKGLEKQVSEL-TESLETK---TSETEAVKTALEEKLEEASSAK 1527
Query: 489 AALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKK--ELVEKEK 546
+ LE +V+ L+ E+A Q K G + E V+ LK+ IS + ++ LKK E +
Sbjct: 1528 SKLETKVTELEKEVADNQGKHGKAASELEASVKTLKSEISTHKATIDELKKSAETAAADT 1587
Query: 547 IVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAV 606
+E + V E + A+A+K L+ K + + S+ +ELK K E+VA
Sbjct: 1588 SSERTELMSKVTELETQLADAKKELDNVKSTHADGS-----KKQASELNELKTKLEEVAT 1642
Query: 607 GRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISA-LQQKCGAGAREGNGDVEV 665
L +K +E ++ KL + E K+++SA + + A + + +V
Sbjct: 1643 ANTKLETELKNASAKLEEEQAAKTKLSSDLEA---KTKVSADFETELKASQTQHDEEVAS 1699
Query: 666 LKAGISDTKKEVN---------RLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEA 716
LK I + E + K E +E E ++E +T ++A++ +
Sbjct: 1700 LKMEIKSLRDEQTSNASSAGEFKGKIEKLEVELKTKETELQTKASNLESASSALEAASKE 1759
Query: 717 PKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKE-ATKRFEAEKKKLLVEKI 775
K A E+E ++++ + LE + E K +T E TK E E K ++
Sbjct: 1760 LKSKATELESASSELKSKTSELESKTTELKTINTELKDRTSELKTKTTELESKS---TEL 1816
Query: 776 NAESKIKKAQERSESELDKKTADMEK 801
S + A E++ +EL K ++ K
Sbjct: 1817 KTVSDTQSATEKALAELQSKYDELLK 1842
Score = 140 bits (353), Expect = 2e-31
Identities = 192/871 (22%), Positives = 372/871 (42%), Gaps = 114/871 (13%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEIS 78
+ +K +++ AL + I++L++ L++D+QE + K A G LE
Sbjct: 720 DNVKSLTDELEEVSTALSETKSATSAEIKDLKAIRDDLERDLQETDTRLKEA-RGALE-- 776
Query: 79 NTFAALENEVSALISENKKLKQDILEEQAQG-----KICDQLKKCEKVVEGRNALRQAVK 133
+LE + ++ K+L+ + E+ G ++ D KK + + + + L V+
Sbjct: 777 ----SLEGKFHTKVAAEKQLQTSLEAERKSGSGLQTELADLKKKLQTLTQQKTQLTTQVE 832
Query: 134 ILEKRIENLESENKKL-----------------KKDIQEEQAQRKIEIEGKLEKSNAFAA 176
L + ES K+ KK +Q+E A+ K + + + A AA
Sbjct: 833 TLTAAKDKAESGINKMSKELFQLTRERDGSDKEKKGLQKELAELKKQDSSRRTELTALAA 892
Query: 177 -----------LENEVSALKSEN-----------KKLKKDI--LEEQAQRKVAMEGKL-E 211
EN + L+SE+ +KLK LE+ R +EG++ E
Sbjct: 893 NLKQVTAARSDFENRLKGLQSEHSETETLKDKLIEKLKSAATQLEDHKSRGANLEGQIRE 952
Query: 212 ISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKIL 271
+ + AL+N L+ +++L D ++ LK K K+ ++ V L
Sbjct: 953 LQGSHEALQNSYDELQKSHEQLSSVGKDNESLASELAELKTKLSKIETESSSRADKVSEL 1012
Query: 272 EKGIENLESENKKLK-----------------KDIQEEHAQRKVEIEG-KLEISNA---F 310
EK + E+++K + K ++EE ++R E++ K +++++
Sbjct: 1013 EKSLSAAEAQSKSVAAEKEKVSGQIATHEETIKRLKEELSERTAELDKLKSDLASSEKDL 1072
Query: 311 AALENEVSALKSENKKLKKDILEEQAQRKVAMEGK-LEI-SNAFAALENEVSALKSENKK 368
A+ +VSA +E +KLK ++ E A K+A K +EI ++ A +++ +++ K
Sbjct: 1073 ASKTKDVSAKDTEIEKLKSEL--ETANSKLASTAKEVEILTSELKAAKSDACDSETKIKA 1130
Query: 369 LKQDILEEQAQGKFCD-QLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQE 427
++ +++E++++ + + +L K V G L + V ++E LES++K+L +E
Sbjct: 1131 VESELVEQKSKVEHLNAELAAKSSSVESGAAELAEKVALVESLTAKLESKDKELATKTEE 1190
Query: 428 EQAQRKIEIEGK---LEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEI 484
A+ K E+E K LE A +++ KS+ ++E A+E+K
Sbjct: 1191 LSAKEK-ELETKTSELETKTAELTTKSKELTAKSDEATTYSAKVKELETSSAALEKKQTT 1249
Query: 485 SNAFAA-LENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVE 543
A A L +++ E+ A + + + + +V+VL +SD E LKK
Sbjct: 1250 LKAMADNLTKDLAEKTKELVAAKSELESSNTSSKEEVDVLTKKLSDATAEAVELKK---- 1305
Query: 544 KEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEK 603
S + + K +A KL +A++ E + + + + + K
Sbjct: 1306 -------SSQAAETEASSKVSALEAKLTKASESSKAELDKVNKLLSSFKEKLQTSKDDHS 1358
Query: 604 VAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGARE-GNGD 662
V + L + V+ EN E + LK ++++ + E AL+ + +E N
Sbjct: 1359 TEVSK--LTEQVRESTLKAENFEHDISSLK--DDLAQAEKERDALRTELDTSIKEMENER 1414
Query: 663 VEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAA 722
+ K S TK+ N++ + + + A K A+ + + A +K ++A +
Sbjct: 1415 TSLTKDADSATKELTNKVSMLQTKLDELTAS--HKKALGDSETEAKGLKKEIKAAQAEIK 1472
Query: 723 EVEKQIAKVELRQVH---LEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAES 779
+E+ AK E Q LEKQV+E L + S+T+ K L EK+ S
Sbjct: 1473 TLEEVKAKYEASQTDIKGLEKQVSELTESLETKTSETEAV--------KTALEEKLEEAS 1524
Query: 780 KIKKAQERSESELDKKTADMEKQQAEEQKKL 810
K E +EL+K+ AD + + + +L
Sbjct: 1525 SAKSKLETKVTELEKEVADNQGKHGKAASEL 1555
Score = 139 bits (350), Expect = 4e-31
Identities = 192/847 (22%), Positives = 377/847 (43%), Gaps = 128/847 (15%)
Query: 21 LKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQ------EEQAQRKVAIEGK 74
L +QV R+ +K L+ E+ KL + ++ E+ R +EG+
Sbjct: 890 LAANLKQVTAARSDFENRLKGLQSEHSETETLKDKLIEKLKSAATQLEDHKSRGANLEGQ 949
Query: 75 L-EISNTFAALEN----------EVSALISENKKLKQDILE--------EQAQGKICDQL 115
+ E+ + AL+N ++S++ +N+ L ++ E E D++
Sbjct: 950 IRELQGSHEALQNSYDELQKSHEQLSSVGKDNESLASELAELKTKLSKIETESSSRADKV 1009
Query: 116 KKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNA-- 173
+ EK + A ++V ++++ + +++ K ++EE ++R E++ KL+ A
Sbjct: 1010 SELEKSLSAAEAQSKSVAAEKEKVSGQIATHEETIKRLKEELSERTAELD-KLKSDLASS 1068
Query: 174 ---FAALENEVSALKSENKKLKKDILEEQAQRKVAMEGK-LEI-SNAFAALENEVSALKS 228
A+ +VSA +E +KLK ++ E A K+A K +EI ++ A +++ ++
Sbjct: 1069 EKDLASKTKDVSAKDTEIEKLKSEL--ETANSKLASTAKEVEILTSELKAAKSDACDSET 1126
Query: 229 ENKKLKQDILDEQAQGKFCD-RLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKK 287
+ K ++ ++++++++ + + L K V G L + V ++E LES++K+L
Sbjct: 1127 KIKAVESELVEQKSKVEHLNAELAAKSSSVESGAAELAEKVALVESLTAKLESKDKELAT 1186
Query: 288 DIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLE 347
+E A+ K E+ + LE + + L +++K+L ++A A +LE
Sbjct: 1187 KTEELSAKEK-------ELETKTSELETKTAELTTKSKELTAK--SDEATTYSAKVKELE 1237
Query: 348 ISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKIL 407
S+A ALE + + LK+ L +D+ E+ + L ++ + ++ V +L
Sbjct: 1238 TSSA--ALEKKQTTLKAMADNLTKDLAEKTKE------LVAAKSELESSNTSSKEEVDVL 1289
Query: 408 EKGIENLESENKKLKKDIQ--EEQAQRKIE-IEGKLEISN--AFAALENEVSALKSESTK 462
K + + +E +LKK Q E +A K+ +E KL ++ + A L+ L S K
Sbjct: 1290 TKKLSDATAEAVELKKSSQAAETEASSKVSALEAKLTKASESSKAELDKVNKLLSSFKEK 1349
Query: 463 LKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEV 522
L+ + ++ E+ E + E+++S+LK ++A +++ A E + ++
Sbjct: 1350 LQTSKDDHSTEVSKLTEQVRESTLKAENFEHDISSLKDDLAQAEKERDALRTELDTSIKE 1409
Query: 523 LKAGISDTEKEVNTLKKELVEK---------------EKIVADSERKTAVDERKKAAAEA 567
++ + K+ ++ KEL K +K + DSE + +++ AA+A
Sbjct: 1410 MENERTSLTKDADSATKELTNKVSMLQTKLDELTASHKKALGDSETEAKGLKKEIKAAQA 1469
Query: 568 R-KLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLE 626
K LE K A +A + + EL + E A++ A LE+ +E E
Sbjct: 1470 EIKTLEEVK--AKYEASQTDIKGLEKQVSELTESLETKTSETEAVKTA---LEEKLE--E 1522
Query: 627 SENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVE 686
+ + K K E +V+ L+ E++ Q K G A E V+ LK+ IS K ++ LKK
Sbjct: 1523 ASSAKSKLETKVTELEKEVADNQGKHGKAASELEASVKTLKSEISTHKATIDELKKS--- 1579
Query: 687 EERIVADS-----ERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQ 741
E AD+ E + V E + A+A+K L+ K A+ K+ A +
Sbjct: 1580 AETAAADTSSERTELMSKVTELETQLADAKKELDNVKSTHADGSKKQAS----------E 1629
Query: 742 VNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEK 801
+NE K KL ++ A + E+EL +A +E+
Sbjct: 1630 LNELKTKL-----------------------------EEVATANTKLETELKNASAKLEE 1660
Query: 802 QQAEEQK 808
+QA + K
Sbjct: 1661 EQAAKTK 1667
Score = 115 bits (288), Expect = 6e-24
Identities = 158/698 (22%), Positives = 291/698 (41%), Gaps = 105/698 (15%)
Query: 130 QAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEG-KLEKSNAFAALENEVSALKSEN 188
+ V+ LE +++L E +++ + E ++ EI+ K + + L+ + LK
Sbjct: 713 ELVQSLEDNVKSLTDELEEVSTALSETKSATSAEIKDLKAIRDDLERDLQETDTRLKEAR 772
Query: 189 KKLKKDILEEQAQRKVAMEGKLEIS-----NAFAALENEVSALKSENKKLKQDILDEQAQ 243
L+ LE + KVA E +L+ S + + L+ E++ LK + + L Q Q
Sbjct: 773 GALES--LEGKFHTKVAAEKQLQTSLEAERKSGSGLQTELADLKKKLQTLTQQKTQLTTQ 830
Query: 244 GKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQE---EHAQRKVEI 300
+ K K E G N + + + L + + + E K L+K++ E + + R+ E+
Sbjct: 831 VETLTAAKDKAES---GINKMSKELFQLTRERDGSDKEKKGLQKELAELKKQDSSRRTEL 887
Query: 301 EGKL----EISNAFAALENEVSALKSEN-----------KKLKKDI--LEEQAQRKVAME 343
+++ A + EN + L+SE+ +KLK LE+ R +E
Sbjct: 888 TALAANLKQVTAARSDFENRLKGLQSEHSETETLKDKLIEKLKSAATQLEDHKSRGANLE 947
Query: 344 GKL-EISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQ 402
G++ E+ + AL+N L+ +++L + ++ +LK K K+ ++
Sbjct: 948 GQIRELQGSHEALQNSYDELQKSHEQLSSVGKDNESLASELAELKTKLSKIETESSSRAD 1007
Query: 403 AVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEI-SNAFAALENEVSALKSEST 461
V LEK + E+++K + A K ++ G++ L+ E+S +E
Sbjct: 1008 KVSELEKSLSAAEAQSKSV--------AAEKEKVSGQIATHEETIKRLKEELSERTAELD 1059
Query: 462 KLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVE 521
KLK D+ + + ++ +A + E+ LKSE+ E
Sbjct: 1060 KLKSDLASSEKDLASKTKD-------VSAKDTEIEKLKSEL------------------E 1094
Query: 522 VLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEK 581
+ ++ T KEV L EL + DSE K E +L+E K+
Sbjct: 1095 TANSKLASTAKEVEILTSELKAAKSDACDSETKIKAVE--------SELVEQKSKVEHLN 1146
Query: 582 AVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKL-KKENEVSA 640
A EL K V G L + V ++E LES++K+L K E+SA
Sbjct: 1147 A-------------ELAAKSSSVESGAAELAEKVALVESLTAKLESKDKELATKTEELSA 1193
Query: 641 LKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAV 700
+ E+ ++E A ++ KE+ E V + E +A
Sbjct: 1194 KEKELET-----------KTSELETKTAELTTKSKELTAKSDEATTYSAKVKELETSSAA 1242
Query: 701 DERKNAAAEARKLLEAPKKIAAEVEKQI--AKVELRQVHL--EKQVNERKMKLAFELSKT 756
E+K +A + + K AE K++ AK EL + +++V+ KL+ ++
Sbjct: 1243 LEKKQTTLKA--MADNLTKDLAEKTKELVAAKSELESSNTSSKEEVDVLTKKLSDATAEA 1300
Query: 757 KEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDK 794
E K +A + + + E+K+ KA E S++ELDK
Sbjct: 1301 VELKKSSQAAETEASSKVSALEAKLTKASESSKAELDK 1338
>emb|CAA98621.1| USO1 [Saccharomyces cerevisiae] gi|6320145|ref|NP_010225.1| Essential
protein involved in intracellular protein transport,
coiled-coil protein necessary for transport from ER to
Golgi; required for assembly of the ER-to-Golgi SNARE
complex; Uso1p [Saccharomyces cerevisiae]
gi|56757595|sp|P25386|USO1_YEAST Intracellular protein
transport protein USO1 (Int-1)
Length = 1790
Score = 152 bits (385), Expect = 3e-35
Identities = 197/864 (22%), Positives = 406/864 (46%), Gaps = 109/864 (12%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRK------VAIE 72
+ LK+ + A+ + ++ ++ NL E + + K++ E +++ + +
Sbjct: 902 KSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLT 961
Query: 73 GKLE-ISNTFAALENEVSALIS--ENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALR 129
KL+ ++N + ++ E +LI E K + I Q KI ++ E R ++
Sbjct: 962 EKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIE 1021
Query: 130 QAVKILEKRIENLESENKKL--KKDIQEEQAQRKIEI-EGKLEKSNAFAALENEVSALKS 186
+ ++ L+K I +LE +++ K D +++ + +I + + KLE A A + V+ + S
Sbjct: 1022 KNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLE--TATTANDENVNKI-S 1078
Query: 187 ENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKF 246
E K ++++ E A K ++ +LE LE ALK E K+ ++ + +E+ Q
Sbjct: 1079 ELTKTREELEAELAAYK-NLKNELETK-----LETSEKALK-EVKENEEHLKEEKIQ--- 1128
Query: 247 CDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEI 306
L+K+ + + N+LR ++ LEK E+L ++ KK ++ I + Q EI
Sbjct: 1129 ---LEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEI------ 1179
Query: 307 SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNA----FAALENEVSAL 362
+ L +E+++ + EN+ +KK E + + K E SN AL ++ L
Sbjct: 1180 ----SQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKEL 1235
Query: 363 KSENKKLKQDILEE----QAQGKFCDQLKKKC----EKVVEGRNALRQAVKILEKGIENL 414
K +N+ + +LE +++ +L+ +C ++V E + L+ + K +E L
Sbjct: 1236 KKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLE-L 1294
Query: 415 ESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQI 474
+ E++K+K+++ + + KI++E +S A E+E+S LK S++ +K+ E+ ++
Sbjct: 1295 QKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKL 1354
Query: 475 KVAIEEKLEISNAFAALENE------------VSALKSEIAALQQKCGAGSRE-GNGDVE 521
K I+ K + L NE ++ L+ E+ LQ + ++E N E
Sbjct: 1355 KNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSE 1414
Query: 522 VLKAGISD---TEKEVNTLK----KELVEKEKIVADSERKTAVD-----------ERKKA 563
+ K +S+ E++ NT+K + L K+KI + E+ +++ E+ +A
Sbjct: 1415 LEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRA 1474
Query: 564 AAEAR-KLLEAAKKI----APEKAVIPEPANCCSKCD--------ELKKKCEKVAVGRNA 610
A E++ K+ E KK+ + EKA + + K + ELK E +
Sbjct: 1475 AQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEK 1534
Query: 611 LRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGI 670
L Q+ K E+ I+NL+ E L + ++ + +I L+ K A+ G+ ++E +K +
Sbjct: 1535 LEQSKKSAEEDIKNLQHEKSDL--ISRINESEKDIEELKSKLRIEAKSGS-ELETVKQEL 1591
Query: 671 SDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAK 730
++ ++++ +E+ + + D ER E K+ AE + E + + + +++ +
Sbjct: 1592 NNAQEKIRINAEENTVLKSKLEDIER-----ELKDKQAEIKSNQEEKELLTSRLKELEQE 1646
Query: 731 VELRQVHLEKQVNERKMKL-AFELSKTKEATKRFEAEKK-KLLVEKINA----ESKIKKA 784
++ Q +K ER+ ++ F++ K++ K E K LV K A E +KK
Sbjct: 1647 LDSTQQKAQKSEEERRAEVRKFQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDTVKKT 1706
Query: 785 QERSESELDKKTADMEKQQAEEQK 808
+ E++K +++ +AE K
Sbjct: 1707 TDSQRQEIEKLAKELDNLKAENSK 1730
Score = 138 bits (347), Expect = 8e-31
Identities = 155/654 (23%), Positives = 313/654 (47%), Gaps = 81/654 (12%)
Query: 20 ELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISN 79
+L+K+ + N+LR ++ LEK E+L ++ KK ++ I ++ Q I ++++
Sbjct: 1128 QLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEIS---QLND 1184
Query: 80 TFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE--------KVVEGRNALRQA 131
+ + E ++ +N +L+ ++ ++ + LKK E K ++ +N +A
Sbjct: 1185 EITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEA 1244
Query: 132 VKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKL 191
+LE I+++ESE K+K ++Q+E ++ E+ +K A ++ L+ E++K+
Sbjct: 1245 -SLLES-IKSVESETVKIK-ELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKI 1301
Query: 192 KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALK---SENKKLKQDILDE---QAQGK 245
K+++ + + K+ +E +S A E+E+S LK SE +K ++ L++ + Q K
Sbjct: 1302 KEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIK 1361
Query: 246 FCDRLKKKCEKVVEGRNALRQA----VKILEKGIENLESENKKLKKDIQEEHAQ-RKVEI 300
+K+ + + EG + + Q + LE + L++EN+ K+I ++ KV +
Sbjct: 1362 N-QAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSL 1420
Query: 301 EGKL---EISNAFAALENEVSALKSE----NKKL-------KKDILEEQAQRKVAMEGKL 346
E N +L++E+ + K + ++KL K+D+ + Q + A E K
Sbjct: 1421 SNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKA 1480
Query: 347 EISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCD-QLKKKCEKVVEGRNALRQAVK 405
++ LE E S K+E +K K+ + + ++ + + +LK E + + L Q+ K
Sbjct: 1481 KVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKK 1540
Query: 406 ILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKK 465
E+ I+NL+ E L I E + + E++ KL I + SE +K+
Sbjct: 1541 SAEEDIKNLQHEKSDLISRINESEKDIE-ELKSKLRIE----------AKSGSELETVKQ 1589
Query: 466 DILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKA 525
++ Q +I++ EE + + +E E+ ++EI + Q+
Sbjct: 1590 ELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQE------------------ 1631
Query: 526 GISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIP 585
EKE+ T + + +E+E DS ++ A ++ AE RK + K EKA++
Sbjct: 1632 -----EKELLTSRLKELEQE---LDSTQQKAQKSEEERRAEVRKF-QVEKSQLDEKAMLL 1682
Query: 586 EPA--NCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENE 637
E + +K K+ + V ++ RQ ++ L K ++NL++EN KLK+ NE
Sbjct: 1683 ETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKELDNLKAENSKLKEANE 1736
Score = 133 bits (334), Expect = 3e-29
Identities = 196/888 (22%), Positives = 397/888 (44%), Gaps = 129/888 (14%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLES---ENKKLKKDIQEEQAQRKVAIEGKL 75
+EL +K + + ++L++ ILE ++N+ E +L+ ++ + + + A+ L
Sbjct: 772 KELDEKYQILNSSHSSLKENFSILETELKNVRDSLDEMTQLRDVLETKDKENQTAL---L 828
Query: 76 EISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE----KVVEGRNALRQA 131
E +T E+ + L E+ I Q KK E K+ + AL +
Sbjct: 829 EYKSTIHKQEDSIKTL-------------EKGLETILSQKKKAEDGINKMGKDLFALSRE 875
Query: 132 VKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNA----FAALENEVSALKSE 187
++ +E+ +NL+ E K + Q+E K +I K+ + A ++ + + L E
Sbjct: 876 MQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKE 935
Query: 188 NKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKF- 246
+ + K+++E +++ + +++ +L N +++EN+ L + + + + +
Sbjct: 936 KEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESSIQ 995
Query: 247 CDRLKKKCEKVVEGRNALRQAVKILEKGIENLE---SENKKLKKDIQEEHAQRKVEIEGK 303
L+ K + + + + + +EK IE L+ S+ ++ K++I + K E E +
Sbjct: 996 LSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQ 1055
Query: 304 LEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEV-SAL 362
+ + E +A + ++ + K + E + + +E +L A+ L+NE+ + L
Sbjct: 1056 ISLLK-----EKLETATTANDENVNK--ISELTKTREELEAELA---AYKNLKNELETKL 1105
Query: 363 KSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLK 422
++ K LK+ E+ + QL+K+ + + N+LR ++ LEK E+L ++ KK +
Sbjct: 1106 ETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYE 1165
Query: 423 KDIQEEQAQRKIEI-----------EGKLEISNAFAALENEVSALKS---ESTKLKKDIL 468
+ I ++ Q EI + I LE EV A+KS E + LKK +
Sbjct: 1166 EQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEI 1225
Query: 469 EE-QAQIKVAIEEKLEISNAFAALENEVSALKSE---IAALQQKCGAGSREGNGDVEVLK 524
+ QIK +++K E + A+L + +++SE I LQ +C +E + + LK
Sbjct: 1226 DALNLQIK-ELKKKNETNE--ASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLK 1282
Query: 525 AGISDTEKEVNTLKKELVEKEKIVADSERKTA--------VDERKKAAAEARKLLEAAKK 576
A K + K E EKI + + KT + KA ++ L KK
Sbjct: 1283 ASEDKNSKYLELQK----ESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKK 1338
Query: 577 IAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKG-----------IENL 625
+ E+ E ++L+K ++ + A + K+L +G I L
Sbjct: 1339 TSSEERKNAE--------EQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTL 1390
Query: 626 ESENKKLKKENEVSA-----LKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRL 680
E E +L+ ENE+ A +SE+ + E ++ L+ I K ++ R
Sbjct: 1391 EDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRN 1450
Query: 681 KKEHVEEERIVADSERK-TAVDERKNAAAEAR-KLLEAPKKIAAEVEKQIAKVELRQVHL 738
++ + ER D++R ++ E+ AA E++ K+ E KK+ E K+ A++E + +
Sbjct: 1451 DEKLLSIER---DNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMM 1507
Query: 739 EK-----QVNERKMKLAFEL-----SKTKEATKRFEAEKKKLLVEKINAESKIKKAQE-- 786
+K + NE ++K + E K +++ K E + K L EK + S+I ++++
Sbjct: 1508 KKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDI 1567
Query: 787 -----------RSESELDKKTADMEKQQAEEQKKLAEDKLLLLGDSLQ 823
+S SEL+ T E A+E+ ++ ++ +L L+
Sbjct: 1568 EELKSKLRIEAKSGSELE--TVKQELNNAQEKIRINAEENTVLKSKLE 1613
Score = 129 bits (324), Expect = 4e-28
Identities = 174/843 (20%), Positives = 354/843 (41%), Gaps = 95/843 (11%)
Query: 46 IENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEE 105
I E K L+K ++ +Q+K A +G ++ AL E+ A + EN K ++ +E
Sbjct: 834 IHKQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSREMQA-VEENCK---NLQKE 889
Query: 106 QAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIE 165
+ + + Q K+ + + E A +K + + +E ++ + L K+ +E ++ +E +
Sbjct: 890 KDKSNVNHQ-KETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKE-KEHISKELVEYK 947
Query: 166 GKLEK-SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVS 224
+ + N A L ++ +L + K ++ E ++ K E K E S + L+N++
Sbjct: 948 SRFQSHDNLVAKLTEKLKSLANNYKDMQA---ENESLIKAVEESKNESSIQLSNLQNKID 1004
Query: 225 ALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKK 284
++ E + + ++ + K ++LKK + + + + + + + ES+
Sbjct: 1005 SMSQEKENFQ---IERGSIEKNIEQLKKTISDLEQTKEEI---ISKSDSSKDEYESQISL 1058
Query: 285 LKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEG 344
LK+ ++ + E++ LE E++A K+ +L+ + + K E
Sbjct: 1059 LKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKEN 1118
Query: 345 KLEISNAFAALENEVSALKSENKKLKQDILE-EQAQGKFCDQLKKKCEKVVEGRNALRQA 403
+ + LE E + K + L+ ++ E+ QLKK E++ +
Sbjct: 1119 EEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEE 1178
Query: 404 VKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKL 463
+ L I + + EN+ +KK E + + K E SN ++E+ AL + +L
Sbjct: 1179 ISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNL---KKSEIDALNLQIKEL 1235
Query: 464 KKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVL 523
KK +A + +I+ + L++E + + E++ L+ K A + + +E+
Sbjct: 1236 KKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQ 1295
Query: 524 KAG--------ISDTEKEVNTLKKELVEKEKIVADSE----RKTAVDERKKAAAEARKLL 571
K TE ++ K + K K ++SE +KT+ +ERK A + KL
Sbjct: 1296 KESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLK 1355
Query: 572 EAAK----KIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLES 627
+ E+ ++ E ++ ++ E +K + L+ ++ K I+N S
Sbjct: 1356 NEIQIKNQAFEKERKLLNEGSSTITQ--EYSEKINTLEDELIRLQNENELKAKEIDNTRS 1413
Query: 628 ENKKL---------KKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVN 678
E +K+ +K+N + +L+ EI + + K + E L + D K+++
Sbjct: 1414 ELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKI-------TRNDEKLLSIERDNKRDLE 1466
Query: 679 RLKKE--HVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVE----------- 725
LK++ +E + + K +E AE K E KK+ + +E
Sbjct: 1467 SLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSME 1526
Query: 726 ---KQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVE--------- 773
K K+E + E+ + + + + +S+ E+ K E K KL +E
Sbjct: 1527 TIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELET 1586
Query: 774 ------------KINAESK--IKKAQERSESELDKKTADMEKQQAEEQKKLAEDKLLLLG 819
+INAE +K E E EL K A+++ Q E+K+L +L L
Sbjct: 1587 VKQELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQ--EEKELLTSRLKELE 1644
Query: 820 DSL 822
L
Sbjct: 1645 QEL 1647
Score = 128 bits (322), Expect = 7e-28
Identities = 165/717 (23%), Positives = 331/717 (46%), Gaps = 89/717 (12%)
Query: 140 ENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQ 199
EN+ L D EE KI E + L+ E+++L++E + +++ E+
Sbjct: 706 ENIYRIRTALSHDPDEEPIN-KISFEEVEKLQRQCTKLKGEITSLQTETESTHENLTEKL 764
Query: 200 ---AQRKVAMEGKLEISNA-FAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCE 255
++ K +I N+ ++L+ S L++E K ++ D LDE Q + K K
Sbjct: 765 IALTNEHKELDEKYQILNSSHSSLKENFSILETELKNVR-DSLDEMTQLRDVLETKDKEN 823
Query: 256 K--VVEGRNALRQ---AVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAF 310
+ ++E ++ + + ++K LEKG+E + S+ KK + I + + +S
Sbjct: 824 QTALLEYKSTIHKQEDSIKTLEKGLETILSQKKKAEDGINKMG-------KDLFALSREM 876
Query: 311 AALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLE----ISNAFAALENEVSALKSEN 366
A+E L+ E K + +E K + K+ I+ ++ + + L E
Sbjct: 877 QAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEK 936
Query: 367 KKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQ 426
+ + ++++E +++ + D L K L + +K L +++++EN+ L K ++
Sbjct: 937 EHISKELVEYKSRFQSHDNLVAK----------LTEKLKSLANNYKDMQAENESLIKAVE 986
Query: 427 EEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISN 486
E + + I++ + N ++ E + E ++K+I + + I + K EI +
Sbjct: 987 ESKNESSIQLSN---LQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIIS 1043
Query: 487 AFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEK 546
+ ++E +S+I+ L++K + + +V IS+ K L+ EL +
Sbjct: 1044 KSDSSKDEY---ESQISLLKEKLETATTANDENVNK----ISELTKTREELEAELAAYKN 1096
Query: 547 IVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAV 606
+ +E +T ++ +KA E ++ E K+ EK +L+K+ +
Sbjct: 1097 L--KNELETKLETSEKALKEVKENEEHLKE---EKI-------------QLEKEATETKQ 1138
Query: 607 GRNALRQAVKILEKGIENLESENKKLKKE---------NEVSALKSEISALQQKCGAGAR 657
N+LR ++ LEK E+L ++ KK +++ E+S L EI++ QQ+ +
Sbjct: 1139 QLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQE-NESIK 1197
Query: 658 EGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAP 717
+ N ++E + T +E + LKK ++ + +K KN EA LLE+
Sbjct: 1198 KKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKK------KNETNEA-SLLESI 1250
Query: 718 KKIAAEVEKQIAKVELRQVHLEKQVNERKMKL-AFELSKTKEATKRFEAEKKKLLVEKIN 776
K + +E K I +++ EK+V+E + KL A E +K + E+EK K ++
Sbjct: 1251 KSVESETVK-IKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKT 1309
Query: 777 AESKIK--------KAQERSESELD--KKTADMEKQQAEEQKKLAEDKLLLLGDSLQ 823
E KI+ KA+E+SESEL KKT+ E++ AEEQ + ++++ + + +
Sbjct: 1310 TELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFE 1366
Score = 60.5 bits (145), Expect = 2e-07
Identities = 75/316 (23%), Positives = 139/316 (43%), Gaps = 39/316 (12%)
Query: 2 ASEKAVIPEPANCCSKCE--------ELKKKCEQVVVGRNALRQAVKILEKGIENLESEN 53
+ EKA + + K E ELK E + L Q+ K E+ I+NL+ E
Sbjct: 1494 SKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEK 1553
Query: 54 KKL-------KKDIQEEQAQRKVAIEGKLEISNTFAALEN---EVSALISENKKLKQDIL 103
L +KDI+E +++ ++ + E+ L N ++ EN LK +
Sbjct: 1554 SDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKL- 1612
Query: 104 EEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQ-RKI 162
E + ++ D+ + + E + L +K LE + L+S +K +K +E +A+ RK
Sbjct: 1613 -EDIERELKDKQAEIKSNQEEKELLTSRLKELE---QELDSTQQKAQKSEEERRAEVRKF 1668
Query: 163 EIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENE 222
++E K + LE + + L ++ + K+D E +K + EI L E
Sbjct: 1669 QVE-KSQLDEKAMLLETKYNDLVNKEQAWKRD---EDTVKKTTDSQRQEIEK----LAKE 1720
Query: 223 VSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESEN 282
+ LK+EN KLK+ D + EK + R+ K+ + G+E + S+
Sbjct: 1721 LDNLKAENSKLKEANEDRSEIDDLMLLVTDLDEKNAKYRS------KLKDLGVE-ISSDE 1773
Query: 283 KKLKKDIQEEHAQRKV 298
+ ++D +E+ + +V
Sbjct: 1774 EDDEEDDEEDEEEGQV 1789
>emb|CAA38253.1| Uso1 protein [Saccharomyces cerevisiae]
Length = 1790
Score = 152 bits (385), Expect = 3e-35
Identities = 197/864 (22%), Positives = 406/864 (46%), Gaps = 109/864 (12%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRK------VAIE 72
+ LK+ + A+ + ++ ++ NL E + + K++ E +++ + +
Sbjct: 902 KSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLT 961
Query: 73 GKLE-ISNTFAALENEVSALIS--ENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALR 129
KL+ ++N + ++ E +LI E K + I Q KI ++ E R ++
Sbjct: 962 EKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIE 1021
Query: 130 QAVKILEKRIENLESENKKL--KKDIQEEQAQRKIEI-EGKLEKSNAFAALENEVSALKS 186
+ ++ L+K I +LE +++ K D +++ + +I + + KLE A A + V+ + S
Sbjct: 1022 KNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLE--TATTANDENVNKI-S 1078
Query: 187 ENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKF 246
E K ++++ E A K ++ +LE LE ALK E K+ ++ + +E+ Q
Sbjct: 1079 ELTKTREELEAELAAYK-NLKNELETK-----LETSEKALK-EVKENEEHLKEEKIQ--- 1128
Query: 247 CDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEI 306
L+K+ + + N+LR ++ LEK E+L ++ KK ++ I + Q EI
Sbjct: 1129 ---LEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEI------ 1179
Query: 307 SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNA----FAALENEVSAL 362
+ L +E+++ + EN+ +KK E + + K E SN AL ++ L
Sbjct: 1180 ----SQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKEL 1235
Query: 363 KSENKKLKQDILEE----QAQGKFCDQLKKKC----EKVVEGRNALRQAVKILEKGIENL 414
K +N+ + +LE +++ +L+ +C ++V E + L+ + K +E L
Sbjct: 1236 KKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLE-L 1294
Query: 415 ESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQI 474
+ E++K+K+++ + + KI++E +S A E+E+S LK S++ +K+ E+ ++
Sbjct: 1295 QKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKL 1354
Query: 475 KVAIEEKLEISNAFAALENE------------VSALKSEIAALQQKCGAGSRE-GNGDVE 521
K I+ K + L NE ++ L+ E+ LQ + ++E N E
Sbjct: 1355 KNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSE 1414
Query: 522 VLKAGISD---TEKEVNTLK----KELVEKEKIVADSERKTAVD-----------ERKKA 563
+ K +S+ E++ NT+K + L K+KI + E+ +++ E+ +A
Sbjct: 1415 LEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRA 1474
Query: 564 AAEAR-KLLEAAKKI----APEKAVIPEPANCCSKCD--------ELKKKCEKVAVGRNA 610
A E++ K+ E KK+ + EKA + + K + ELK E +
Sbjct: 1475 AQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEK 1534
Query: 611 LRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGI 670
L Q+ K E+ I+NL+ E L + ++ + +I L+ K A+ G+ ++E +K +
Sbjct: 1535 LEQSKKSAEEDIKNLQHEKSDL--ISRINESEKDIEELKSKLRIEAKSGS-ELETVKQEL 1591
Query: 671 SDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAK 730
++ ++++ +E+ + + D ER E K+ AE + E + + + +++ +
Sbjct: 1592 NNAQEKIRINAEENTVLKSKLEDIER-----ELKDKQAEIKSNQEEKELLTSRLKELEQE 1646
Query: 731 VELRQVHLEKQVNERKMKL-AFELSKTKEATKRFEAEKK-KLLVEKINA----ESKIKKA 784
++ Q +K ER+ ++ F++ K++ K E K LV K A E +KK
Sbjct: 1647 LDSTQQKAQKSEEERRAEVRKFQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDTVKKT 1706
Query: 785 QERSESELDKKTADMEKQQAEEQK 808
+ E++K +++ +AE K
Sbjct: 1707 TDSQRQEIEKLAKELDNLKAENSK 1730
Score = 138 bits (347), Expect = 8e-31
Identities = 155/654 (23%), Positives = 313/654 (47%), Gaps = 81/654 (12%)
Query: 20 ELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISN 79
+L+K+ + N+LR ++ LEK E+L ++ KK ++ I ++ Q I ++++
Sbjct: 1128 QLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEIS---QLND 1184
Query: 80 TFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE--------KVVEGRNALRQA 131
+ + E ++ +N +L+ ++ ++ + LKK E K ++ +N +A
Sbjct: 1185 EITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEA 1244
Query: 132 VKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKL 191
+LE I+++ESE K+K ++Q+E ++ E+ +K A ++ L+ E++K+
Sbjct: 1245 -SLLES-IKSVESETVKIK-ELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKI 1301
Query: 192 KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALK---SENKKLKQDILDE---QAQGK 245
K+++ + + K+ +E +S A E+E+S LK SE +K ++ L++ + Q K
Sbjct: 1302 KEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIK 1361
Query: 246 FCDRLKKKCEKVVEGRNALRQA----VKILEKGIENLESENKKLKKDIQEEHAQ-RKVEI 300
+K+ + + EG + + Q + LE + L++EN+ K+I ++ KV +
Sbjct: 1362 N-QAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSL 1420
Query: 301 EGKL---EISNAFAALENEVSALKSE----NKKL-------KKDILEEQAQRKVAMEGKL 346
E N +L++E+ + K + ++KL K+D+ + Q + A E K
Sbjct: 1421 SNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKA 1480
Query: 347 EISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCD-QLKKKCEKVVEGRNALRQAVK 405
++ LE E S K+E +K K+ + + ++ + + +LK E + + L Q+ K
Sbjct: 1481 KVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKK 1540
Query: 406 ILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKK 465
E+ I+NL+ E L I E + + E++ KL I + SE +K+
Sbjct: 1541 SAEEDIKNLQHEKSDLISRINESEKDIE-ELKSKLRIE----------AKSGSELETVKQ 1589
Query: 466 DILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKA 525
++ Q +I++ EE + + +E E+ ++EI + Q+
Sbjct: 1590 ELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQE------------------ 1631
Query: 526 GISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIP 585
EKE+ T + + +E+E DS ++ A ++ AE RK + K EKA++
Sbjct: 1632 -----EKELLTSRLKELEQE---LDSTQQKAQKSEEERRAEVRKF-QVEKSQLDEKAMLL 1682
Query: 586 EPA--NCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENE 637
E + +K K+ + V ++ RQ ++ L K ++NL++EN KLK+ NE
Sbjct: 1683 ETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKELDNLKAENSKLKEANE 1736
Score = 133 bits (334), Expect = 3e-29
Identities = 196/888 (22%), Positives = 397/888 (44%), Gaps = 129/888 (14%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLES---ENKKLKKDIQEEQAQRKVAIEGKL 75
+EL +K + + ++L++ ILE ++N+ E +L+ ++ + + + A+ L
Sbjct: 772 KELDEKYQILNSSHSSLKENFSILETELKNVRDSLDEMTQLRDVLETKDKENQTAL---L 828
Query: 76 EISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE----KVVEGRNALRQA 131
E +T E+ + L E+ I Q KK E K+ + AL +
Sbjct: 829 EYKSTIHKQEDSIKTL-------------EKGLETILSQKKKAEDGINKMGKDLFALSRE 875
Query: 132 VKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNA----FAALENEVSALKSE 187
++ +E+ +NL+ E K + Q+E K +I K+ + A ++ + + L E
Sbjct: 876 MQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKE 935
Query: 188 NKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKF- 246
+ + K+++E +++ + +++ +L N +++EN+ L + + + + +
Sbjct: 936 KEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESSIQ 995
Query: 247 CDRLKKKCEKVVEGRNALRQAVKILEKGIENLE---SENKKLKKDIQEEHAQRKVEIEGK 303
L+ K + + + + + +EK IE L+ S+ ++ K++I + K E E +
Sbjct: 996 LSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQ 1055
Query: 304 LEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEV-SAL 362
+ + E +A + ++ + K + E + + +E +L A+ L+NE+ + L
Sbjct: 1056 ISLLK-----EKLETATTANDENVNK--ISELTKTREELEAELA---AYKNLKNELETKL 1105
Query: 363 KSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLK 422
++ K LK+ E+ + QL+K+ + + N+LR ++ LEK E+L ++ KK +
Sbjct: 1106 ETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYE 1165
Query: 423 KDIQEEQAQRKIEI-----------EGKLEISNAFAALENEVSALKS---ESTKLKKDIL 468
+ I ++ Q EI + I LE EV A+KS E + LKK +
Sbjct: 1166 EQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEI 1225
Query: 469 EE-QAQIKVAIEEKLEISNAFAALENEVSALKSE---IAALQQKCGAGSREGNGDVEVLK 524
+ QIK +++K E + A+L + +++SE I LQ +C +E + + LK
Sbjct: 1226 DALNLQIK-ELKKKNETNE--ASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLK 1282
Query: 525 AGISDTEKEVNTLKKELVEKEKIVADSERKTA--------VDERKKAAAEARKLLEAAKK 576
A K + K E EKI + + KT + KA ++ L KK
Sbjct: 1283 ASEDKNSKYLELQK----ESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKK 1338
Query: 577 IAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKG-----------IENL 625
+ E+ E ++L+K ++ + A + K+L +G I L
Sbjct: 1339 TSSEERKNAE--------EQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTL 1390
Query: 626 ESENKKLKKENEVSA-----LKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRL 680
E E +L+ ENE+ A +SE+ + E ++ L+ I K ++ R
Sbjct: 1391 EDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRN 1450
Query: 681 KKEHVEEERIVADSERK-TAVDERKNAAAEAR-KLLEAPKKIAAEVEKQIAKVELRQVHL 738
++ + ER D++R ++ E+ AA E++ K+ E KK+ E K+ A++E + +
Sbjct: 1451 DEKLLSIER---DNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMM 1507
Query: 739 EK-----QVNERKMKLAFEL-----SKTKEATKRFEAEKKKLLVEKINAESKIKKAQE-- 786
+K + NE ++K + E K +++ K E + K L EK + S+I ++++
Sbjct: 1508 KKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDI 1567
Query: 787 -----------RSESELDKKTADMEKQQAEEQKKLAEDKLLLLGDSLQ 823
+S SEL+ T E A+E+ ++ ++ +L L+
Sbjct: 1568 EELKSKLRIEAKSGSELE--TVKQELNNAQEKIRINAEENTVLKSKLE 1613
Score = 129 bits (324), Expect = 4e-28
Identities = 174/843 (20%), Positives = 354/843 (41%), Gaps = 95/843 (11%)
Query: 46 IENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEE 105
I E K L+K ++ +Q+K A +G ++ AL E+ A + EN K ++ +E
Sbjct: 834 IHKQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSREMQA-VEENCK---NLQKE 889
Query: 106 QAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIE 165
+ + + Q K+ + + E A +K + + +E ++ + L K+ +E ++ +E +
Sbjct: 890 KDKSNVNHQ-KETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKE-KEHISKELVEYK 947
Query: 166 GKLEK-SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVS 224
+ + N A L ++ +L + K ++ E ++ K E K E S + L+N++
Sbjct: 948 SRFQSHDNLVAKLTEKLKSLANNYKDMQA---ENESLIKAVEESKNESSIQLSNLQNKID 1004
Query: 225 ALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKK 284
++ E + + ++ + K ++LKK + + + + + + + ES+
Sbjct: 1005 SMSQEKENFQ---IERGSIEKNIEQLKKTISDLEQTKEEI---ISKSDSSKDEYESQISL 1058
Query: 285 LKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEG 344
LK+ ++ + E++ LE E++A K+ +L+ + + K E
Sbjct: 1059 LKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKEN 1118
Query: 345 KLEISNAFAALENEVSALKSENKKLKQDILE-EQAQGKFCDQLKKKCEKVVEGRNALRQA 403
+ + LE E + K + L+ ++ E+ QLKK E++ +
Sbjct: 1119 EEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEE 1178
Query: 404 VKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKL 463
+ L I + + EN+ +KK E + + K E SN ++E+ AL + +L
Sbjct: 1179 ISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNL---KKSEIDALNLQIKEL 1235
Query: 464 KKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVL 523
KK +A + +I+ + L++E + + E++ L+ K A + + +E+
Sbjct: 1236 KKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQ 1295
Query: 524 KAG--------ISDTEKEVNTLKKELVEKEKIVADSE----RKTAVDERKKAAAEARKLL 571
K TE ++ K + K K ++SE +KT+ +ERK A + KL
Sbjct: 1296 KESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLK 1355
Query: 572 EAAK----KIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLES 627
+ E+ ++ E ++ ++ E +K + L+ ++ K I+N S
Sbjct: 1356 NEIQIKNQAFEKERKLLNEGSSTITQ--EYSEKINTLEDELIRLQNENELKAKEIDNTRS 1413
Query: 628 ENKKL---------KKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVN 678
E +K+ +K+N + +L+ EI + + K + E L + D K+++
Sbjct: 1414 ELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKI-------TRNDEKLLSIERDNKRDLE 1466
Query: 679 RLKKE--HVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVE----------- 725
LK++ +E + + K +E AE K E KK+ + +E
Sbjct: 1467 SLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSME 1526
Query: 726 ---KQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVE--------- 773
K K+E + E+ + + + + +S+ E+ K E K KL +E
Sbjct: 1527 TIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELET 1586
Query: 774 ------------KINAESK--IKKAQERSESELDKKTADMEKQQAEEQKKLAEDKLLLLG 819
+INAE +K E E EL K A+++ Q E+K+L +L L
Sbjct: 1587 VKQELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQ--EEKELLTSRLKELE 1644
Query: 820 DSL 822
L
Sbjct: 1645 QEL 1647
Score = 128 bits (322), Expect = 7e-28
Identities = 165/717 (23%), Positives = 331/717 (46%), Gaps = 89/717 (12%)
Query: 140 ENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQ 199
EN+ L D EE KI E + L+ E+++L++E + +++ E+
Sbjct: 706 ENIYRIRTALSHDPDEEPIS-KISFEEVEKLQRQCTKLKGEITSLQTETESTHENLTEKL 764
Query: 200 ---AQRKVAMEGKLEISNA-FAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCE 255
++ K +I N+ ++L+ S L++E K ++ D LDE Q + K K
Sbjct: 765 IALTNEHKELDEKYQILNSSHSSLKENFSILETELKNVR-DSLDEMTQLRDVLETKDKEN 823
Query: 256 K--VVEGRNALRQ---AVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAF 310
+ ++E ++ + + ++K LEKG+E + S+ KK + I + + +S
Sbjct: 824 QTALLEYKSTIHKQEDSIKTLEKGLETILSQKKKAEDGINKMG-------KDLFALSREM 876
Query: 311 AALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLE----ISNAFAALENEVSALKSEN 366
A+E L+ E K + +E K + K+ I+ ++ + + L E
Sbjct: 877 QAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEK 936
Query: 367 KKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQ 426
+ + ++++E +++ + D L K L + +K L +++++EN+ L K ++
Sbjct: 937 EHISKELVEYKSRFQSHDNLVAK----------LTEKLKSLANNYKDMQAENESLIKAVE 986
Query: 427 EEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISN 486
E + + I++ + N ++ E + E ++K+I + + I + K EI +
Sbjct: 987 ESKNESSIQLSN---LQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIIS 1043
Query: 487 AFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEK 546
+ ++E +S+I+ L++K + + +V IS+ K L+ EL +
Sbjct: 1044 KSDSSKDEY---ESQISLLKEKLETATTANDENVNK----ISELTKTREELEAELAAYKN 1096
Query: 547 IVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAV 606
+ +E +T ++ +KA E ++ E K+ EK +L+K+ +
Sbjct: 1097 L--KNELETKLETSEKALKEVKENEEHLKE---EKI-------------QLEKEATETKQ 1138
Query: 607 GRNALRQAVKILEKGIENLESENKKLKKE---------NEVSALKSEISALQQKCGAGAR 657
N+LR ++ LEK E+L ++ KK +++ E+S L EI++ QQ+ +
Sbjct: 1139 QLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQE-NESIK 1197
Query: 658 EGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAP 717
+ N ++E + T +E + LKK ++ + +K KN EA LLE+
Sbjct: 1198 KKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKK------KNETNEA-SLLESI 1250
Query: 718 KKIAAEVEKQIAKVELRQVHLEKQVNERKMKL-AFELSKTKEATKRFEAEKKKLLVEKIN 776
K + +E K I +++ EK+V+E + KL A E +K + E+EK K ++
Sbjct: 1251 KSVESETVK-IKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKT 1309
Query: 777 AESKIK--------KAQERSESELD--KKTADMEKQQAEEQKKLAEDKLLLLGDSLQ 823
E KI+ KA+E+SESEL KKT+ E++ AEEQ + ++++ + + +
Sbjct: 1310 TELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFE 1366
Score = 60.5 bits (145), Expect = 2e-07
Identities = 75/316 (23%), Positives = 139/316 (43%), Gaps = 39/316 (12%)
Query: 2 ASEKAVIPEPANCCSKCE--------ELKKKCEQVVVGRNALRQAVKILEKGIENLESEN 53
+ EKA + + K E ELK E + L Q+ K E+ I+NL+ E
Sbjct: 1494 SKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEK 1553
Query: 54 KKL-------KKDIQEEQAQRKVAIEGKLEISNTFAALEN---EVSALISENKKLKQDIL 103
L +KDI+E +++ ++ + E+ L N ++ EN LK +
Sbjct: 1554 SDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKL- 1612
Query: 104 EEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQ-RKI 162
E + ++ D+ + + E + L +K LE + L+S +K +K +E +A+ RK
Sbjct: 1613 -EDIERELKDKQAEIKSNQEEKELLTSRLKELE---QELDSTQQKAQKSEEERRAEVRKF 1668
Query: 163 EIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENE 222
++E K + LE + + L ++ + K+D E +K + EI L E
Sbjct: 1669 QVE-KSQLDEKAMLLETKYNDLVNKEQAWKRD---EDTVKKTTDSQRQEIEK----LAKE 1720
Query: 223 VSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESEN 282
+ LK+EN KLK+ D + EK + R+ K+ + G+E + S+
Sbjct: 1721 LDNLKAENSKLKEANEDRSEIDDLMLLVTDLDEKNAKYRS------KLKDLGVE-ISSDE 1773
Query: 283 KKLKKDIQEEHAQRKV 298
+ ++D +E+ + +V
Sbjct: 1774 EDDEEDDEEDEEEGQV 1789
>emb|CAA98620.1| USO1 [Saccharomyces cerevisiae]
Length = 1268
Score = 152 bits (385), Expect = 3e-35
Identities = 197/864 (22%), Positives = 406/864 (46%), Gaps = 109/864 (12%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRK------VAIE 72
+ LK+ + A+ + ++ ++ NL E + + K++ E +++ + +
Sbjct: 380 KSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLT 439
Query: 73 GKLE-ISNTFAALENEVSALIS--ENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALR 129
KL+ ++N + ++ E +LI E K + I Q KI ++ E R ++
Sbjct: 440 EKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIE 499
Query: 130 QAVKILEKRIENLESENKKL--KKDIQEEQAQRKIEI-EGKLEKSNAFAALENEVSALKS 186
+ ++ L+K I +LE +++ K D +++ + +I + + KLE A A + V+ + S
Sbjct: 500 KNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLE--TATTANDENVNKI-S 556
Query: 187 ENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKF 246
E K ++++ E A K ++ +LE LE ALK E K+ ++ + +E+ Q
Sbjct: 557 ELTKTREELEAELAAYK-NLKNELETK-----LETSEKALK-EVKENEEHLKEEKIQ--- 606
Query: 247 CDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEI 306
L+K+ + + N+LR ++ LEK E+L ++ KK ++ I + Q EI
Sbjct: 607 ---LEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEI------ 657
Query: 307 SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNA----FAALENEVSAL 362
+ L +E+++ + EN+ +KK E + + K E SN AL ++ L
Sbjct: 658 ----SQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKEL 713
Query: 363 KSENKKLKQDILEE----QAQGKFCDQLKKKC----EKVVEGRNALRQAVKILEKGIENL 414
K +N+ + +LE +++ +L+ +C ++V E + L+ + K +E L
Sbjct: 714 KKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLE-L 772
Query: 415 ESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQI 474
+ E++K+K+++ + + KI++E +S A E+E+S LK S++ +K+ E+ ++
Sbjct: 773 QKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKL 832
Query: 475 KVAIEEKLEISNAFAALENE------------VSALKSEIAALQQKCGAGSRE-GNGDVE 521
K I+ K + L NE ++ L+ E+ LQ + ++E N E
Sbjct: 833 KNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSE 892
Query: 522 VLKAGISD---TEKEVNTLK----KELVEKEKIVADSERKTAVD-----------ERKKA 563
+ K +S+ E++ NT+K + L K+KI + E+ +++ E+ +A
Sbjct: 893 LEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRA 952
Query: 564 AAEAR-KLLEAAKKI----APEKAVIPEPANCCSKCD--------ELKKKCEKVAVGRNA 610
A E++ K+ E KK+ + EKA + + K + ELK E +
Sbjct: 953 AQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEK 1012
Query: 611 LRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGI 670
L Q+ K E+ I+NL+ E L + ++ + +I L+ K A+ G+ ++E +K +
Sbjct: 1013 LEQSKKSAEEDIKNLQHEKSDL--ISRINESEKDIEELKSKLRIEAKSGS-ELETVKQEL 1069
Query: 671 SDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAK 730
++ ++++ +E+ + + D ER E K+ AE + E + + + +++ +
Sbjct: 1070 NNAQEKIRINAEENTVLKSKLEDIER-----ELKDKQAEIKSNQEEKELLTSRLKELEQE 1124
Query: 731 VELRQVHLEKQVNERKMKL-AFELSKTKEATKRFEAEKK-KLLVEKINA----ESKIKKA 784
++ Q +K ER+ ++ F++ K++ K E K LV K A E +KK
Sbjct: 1125 LDSTQQKAQKSEEERRAEVRKFQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDTVKKT 1184
Query: 785 QERSESELDKKTADMEKQQAEEQK 808
+ E++K +++ +AE K
Sbjct: 1185 TDSQRQEIEKLAKELDNLKAENSK 1208
Score = 138 bits (347), Expect = 8e-31
Identities = 155/654 (23%), Positives = 313/654 (47%), Gaps = 81/654 (12%)
Query: 20 ELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISN 79
+L+K+ + N+LR ++ LEK E+L ++ KK ++ I ++ Q I ++++
Sbjct: 606 QLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEIS---QLND 662
Query: 80 TFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE--------KVVEGRNALRQA 131
+ + E ++ +N +L+ ++ ++ + LKK E K ++ +N +A
Sbjct: 663 EITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEA 722
Query: 132 VKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKL 191
+LE I+++ESE K+K ++Q+E ++ E+ +K A ++ L+ E++K+
Sbjct: 723 -SLLES-IKSVESETVKIK-ELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKI 779
Query: 192 KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALK---SENKKLKQDILDE---QAQGK 245
K+++ + + K+ +E +S A E+E+S LK SE +K ++ L++ + Q K
Sbjct: 780 KEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIK 839
Query: 246 FCDRLKKKCEKVVEGRNALRQA----VKILEKGIENLESENKKLKKDIQEEHAQ-RKVEI 300
+K+ + + EG + + Q + LE + L++EN+ K+I ++ KV +
Sbjct: 840 N-QAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSL 898
Query: 301 EGKL---EISNAFAALENEVSALKSE----NKKL-------KKDILEEQAQRKVAMEGKL 346
E N +L++E+ + K + ++KL K+D+ + Q + A E K
Sbjct: 899 SNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKA 958
Query: 347 EISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCD-QLKKKCEKVVEGRNALRQAVK 405
++ LE E S K+E +K K+ + + ++ + + +LK E + + L Q+ K
Sbjct: 959 KVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKK 1018
Query: 406 ILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKK 465
E+ I+NL+ E L I E + + E++ KL I + SE +K+
Sbjct: 1019 SAEEDIKNLQHEKSDLISRINESEKDIE-ELKSKLRIE----------AKSGSELETVKQ 1067
Query: 466 DILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKA 525
++ Q +I++ EE + + +E E+ ++EI + Q+
Sbjct: 1068 ELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQE------------------ 1109
Query: 526 GISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIP 585
EKE+ T + + +E+E DS ++ A ++ AE RK + K EKA++
Sbjct: 1110 -----EKELLTSRLKELEQE---LDSTQQKAQKSEEERRAEVRKF-QVEKSQLDEKAMLL 1160
Query: 586 EPA--NCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENE 637
E + +K K+ + V ++ RQ ++ L K ++NL++EN KLK+ NE
Sbjct: 1161 ETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKELDNLKAENSKLKEANE 1214
Score = 133 bits (334), Expect = 3e-29
Identities = 196/888 (22%), Positives = 397/888 (44%), Gaps = 129/888 (14%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLES---ENKKLKKDIQEEQAQRKVAIEGKL 75
+EL +K + + ++L++ ILE ++N+ E +L+ ++ + + + A+ L
Sbjct: 250 KELDEKYQILNSSHSSLKENFSILETELKNVRDSLDEMTQLRDVLETKDKENQTAL---L 306
Query: 76 EISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE----KVVEGRNALRQA 131
E +T E+ + L E+ I Q KK E K+ + AL +
Sbjct: 307 EYKSTIHKQEDSIKTL-------------EKGLETILSQKKKAEDGINKMGKDLFALSRE 353
Query: 132 VKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNA----FAALENEVSALKSE 187
++ +E+ +NL+ E K + Q+E K +I K+ + A ++ + + L E
Sbjct: 354 MQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKE 413
Query: 188 NKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKF- 246
+ + K+++E +++ + +++ +L N +++EN+ L + + + + +
Sbjct: 414 KEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESSIQ 473
Query: 247 CDRLKKKCEKVVEGRNALRQAVKILEKGIENLE---SENKKLKKDIQEEHAQRKVEIEGK 303
L+ K + + + + + +EK IE L+ S+ ++ K++I + K E E +
Sbjct: 474 LSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQ 533
Query: 304 LEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEV-SAL 362
+ + E +A + ++ + K + E + + +E +L A+ L+NE+ + L
Sbjct: 534 ISLLK-----EKLETATTANDENVNK--ISELTKTREELEAELA---AYKNLKNELETKL 583
Query: 363 KSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLK 422
++ K LK+ E+ + QL+K+ + + N+LR ++ LEK E+L ++ KK +
Sbjct: 584 ETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYE 643
Query: 423 KDIQEEQAQRKIEI-----------EGKLEISNAFAALENEVSALKS---ESTKLKKDIL 468
+ I ++ Q EI + I LE EV A+KS E + LKK +
Sbjct: 644 EQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEI 703
Query: 469 EE-QAQIKVAIEEKLEISNAFAALENEVSALKSE---IAALQQKCGAGSREGNGDVEVLK 524
+ QIK +++K E + A+L + +++SE I LQ +C +E + + LK
Sbjct: 704 DALNLQIK-ELKKKNETNE--ASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLK 760
Query: 525 AGISDTEKEVNTLKKELVEKEKIVADSERKTA--------VDERKKAAAEARKLLEAAKK 576
A K + K E EKI + + KT + KA ++ L KK
Sbjct: 761 ASEDKNSKYLELQK----ESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKK 816
Query: 577 IAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKG-----------IENL 625
+ E+ E ++L+K ++ + A + K+L +G I L
Sbjct: 817 TSSEERKNAE--------EQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTL 868
Query: 626 ESENKKLKKENEVSA-----LKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRL 680
E E +L+ ENE+ A +SE+ + E ++ L+ I K ++ R
Sbjct: 869 EDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRN 928
Query: 681 KKEHVEEERIVADSERK-TAVDERKNAAAEAR-KLLEAPKKIAAEVEKQIAKVELRQVHL 738
++ + ER D++R ++ E+ AA E++ K+ E KK+ E K+ A++E + +
Sbjct: 929 DEKLLSIER---DNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMM 985
Query: 739 EK-----QVNERKMKLAFEL-----SKTKEATKRFEAEKKKLLVEKINAESKIKKAQE-- 786
+K + NE ++K + E K +++ K E + K L EK + S+I ++++
Sbjct: 986 KKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDI 1045
Query: 787 -----------RSESELDKKTADMEKQQAEEQKKLAEDKLLLLGDSLQ 823
+S SEL+ T E A+E+ ++ ++ +L L+
Sbjct: 1046 EELKSKLRIEAKSGSELE--TVKQELNNAQEKIRINAEENTVLKSKLE 1091
Score = 129 bits (324), Expect = 4e-28
Identities = 174/843 (20%), Positives = 354/843 (41%), Gaps = 95/843 (11%)
Query: 46 IENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEE 105
I E K L+K ++ +Q+K A +G ++ AL E+ A + EN K ++ +E
Sbjct: 312 IHKQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSREMQA-VEENCK---NLQKE 367
Query: 106 QAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIE 165
+ + + Q K+ + + E A +K + + +E ++ + L K+ +E ++ +E +
Sbjct: 368 KDKSNVNHQ-KETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKE-KEHISKELVEYK 425
Query: 166 GKLEK-SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVS 224
+ + N A L ++ +L + K ++ E ++ K E K E S + L+N++
Sbjct: 426 SRFQSHDNLVAKLTEKLKSLANNYKDMQA---ENESLIKAVEESKNESSIQLSNLQNKID 482
Query: 225 ALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKK 284
++ E + + ++ + K ++LKK + + + + + + + ES+
Sbjct: 483 SMSQEKENFQ---IERGSIEKNIEQLKKTISDLEQTKEEI---ISKSDSSKDEYESQISL 536
Query: 285 LKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEG 344
LK+ ++ + E++ LE E++A K+ +L+ + + K E
Sbjct: 537 LKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKEN 596
Query: 345 KLEISNAFAALENEVSALKSENKKLKQDILE-EQAQGKFCDQLKKKCEKVVEGRNALRQA 403
+ + LE E + K + L+ ++ E+ QLKK E++ +
Sbjct: 597 EEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEE 656
Query: 404 VKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKL 463
+ L I + + EN+ +KK E + + K E SN ++E+ AL + +L
Sbjct: 657 ISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNL---KKSEIDALNLQIKEL 713
Query: 464 KKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVL 523
KK +A + +I+ + L++E + + E++ L+ K A + + +E+
Sbjct: 714 KKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQ 773
Query: 524 KAG--------ISDTEKEVNTLKKELVEKEKIVADSE----RKTAVDERKKAAAEARKLL 571
K TE ++ K + K K ++SE +KT+ +ERK A + KL
Sbjct: 774 KESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLK 833
Query: 572 EAAK----KIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLES 627
+ E+ ++ E ++ ++ E +K + L+ ++ K I+N S
Sbjct: 834 NEIQIKNQAFEKERKLLNEGSSTITQ--EYSEKINTLEDELIRLQNENELKAKEIDNTRS 891
Query: 628 ENKKL---------KKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVN 678
E +K+ +K+N + +L+ EI + + K + E L + D K+++
Sbjct: 892 ELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKI-------TRNDEKLLSIERDNKRDLE 944
Query: 679 RLKKE--HVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVE----------- 725
LK++ +E + + K +E AE K E KK+ + +E
Sbjct: 945 SLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSME 1004
Query: 726 ---KQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVE--------- 773
K K+E + E+ + + + + +S+ E+ K E K KL +E
Sbjct: 1005 TIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELET 1064
Query: 774 ------------KINAESK--IKKAQERSESELDKKTADMEKQQAEEQKKLAEDKLLLLG 819
+INAE +K E E EL K A+++ Q E+K+L +L L
Sbjct: 1065 VKQELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQ--EEKELLTSRLKELE 1122
Query: 820 DSL 822
L
Sbjct: 1123 QEL 1125
Score = 128 bits (322), Expect = 7e-28
Identities = 165/717 (23%), Positives = 331/717 (46%), Gaps = 89/717 (12%)
Query: 140 ENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQ 199
EN+ L D EE KI E + L+ E+++L++E + +++ E+
Sbjct: 184 ENIYRIRTALSHDPDEEPIN-KISFEEVEKLQRQCTKLKGEITSLQTETESTHENLTEKL 242
Query: 200 ---AQRKVAMEGKLEISNA-FAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCE 255
++ K +I N+ ++L+ S L++E K ++ D LDE Q + K K
Sbjct: 243 IALTNEHKELDEKYQILNSSHSSLKENFSILETELKNVR-DSLDEMTQLRDVLETKDKEN 301
Query: 256 K--VVEGRNALRQ---AVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAF 310
+ ++E ++ + + ++K LEKG+E + S+ KK + I + + +S
Sbjct: 302 QTALLEYKSTIHKQEDSIKTLEKGLETILSQKKKAEDGINKMG-------KDLFALSREM 354
Query: 311 AALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLE----ISNAFAALENEVSALKSEN 366
A+E L+ E K + +E K + K+ I+ ++ + + L E
Sbjct: 355 QAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEK 414
Query: 367 KKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQ 426
+ + ++++E +++ + D L K L + +K L +++++EN+ L K ++
Sbjct: 415 EHISKELVEYKSRFQSHDNLVAK----------LTEKLKSLANNYKDMQAENESLIKAVE 464
Query: 427 EEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISN 486
E + + I++ + N ++ E + E ++K+I + + I + K EI +
Sbjct: 465 ESKNESSIQLSN---LQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIIS 521
Query: 487 AFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEK 546
+ ++E +S+I+ L++K + + +V IS+ K L+ EL +
Sbjct: 522 KSDSSKDEY---ESQISLLKEKLETATTANDENVNK----ISELTKTREELEAELAAYKN 574
Query: 547 IVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAV 606
+ +E +T ++ +KA E ++ E K+ EK +L+K+ +
Sbjct: 575 L--KNELETKLETSEKALKEVKENEEHLKE---EKI-------------QLEKEATETKQ 616
Query: 607 GRNALRQAVKILEKGIENLESENKKLKKE---------NEVSALKSEISALQQKCGAGAR 657
N+LR ++ LEK E+L ++ KK +++ E+S L EI++ QQ+ +
Sbjct: 617 QLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQE-NESIK 675
Query: 658 EGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAP 717
+ N ++E + T +E + LKK ++ + +K KN EA LLE+
Sbjct: 676 KKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKK------KNETNEA-SLLESI 728
Query: 718 KKIAAEVEKQIAKVELRQVHLEKQVNERKMKL-AFELSKTKEATKRFEAEKKKLLVEKIN 776
K + +E K I +++ EK+V+E + KL A E +K + E+EK K ++
Sbjct: 729 KSVESETVK-IKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKT 787
Query: 777 AESKIK--------KAQERSESELD--KKTADMEKQQAEEQKKLAEDKLLLLGDSLQ 823
E KI+ KA+E+SESEL KKT+ E++ AEEQ + ++++ + + +
Sbjct: 788 TELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFE 844
Score = 60.5 bits (145), Expect = 2e-07
Identities = 75/316 (23%), Positives = 139/316 (43%), Gaps = 39/316 (12%)
Query: 2 ASEKAVIPEPANCCSKCE--------ELKKKCEQVVVGRNALRQAVKILEKGIENLESEN 53
+ EKA + + K E ELK E + L Q+ K E+ I+NL+ E
Sbjct: 972 SKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEK 1031
Query: 54 KKL-------KKDIQEEQAQRKVAIEGKLEISNTFAALEN---EVSALISENKKLKQDIL 103
L +KDI+E +++ ++ + E+ L N ++ EN LK +
Sbjct: 1032 SDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKL- 1090
Query: 104 EEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQ-RKI 162
E + ++ D+ + + E + L +K LE + L+S +K +K +E +A+ RK
Sbjct: 1091 -EDIERELKDKQAEIKSNQEEKELLTSRLKELE---QELDSTQQKAQKSEEERRAEVRKF 1146
Query: 163 EIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENE 222
++E K + LE + + L ++ + K+D E +K + EI L E
Sbjct: 1147 QVE-KSQLDEKAMLLETKYNDLVNKEQAWKRD---EDTVKKTTDSQRQEIEK----LAKE 1198
Query: 223 VSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESEN 282
+ LK+EN KLK+ D + EK + R+ K+ + G+E + S+
Sbjct: 1199 LDNLKAENSKLKEANEDRSEIDDLMLLVTDLDEKNAKYRS------KLKDLGVE-ISSDE 1251
Query: 283 KKLKKDIQEEHAQRKV 298
+ ++D +E+ + +V
Sbjct: 1252 EDDEEDDEEDEEEGQV 1267
>gb|AAB00143.1| putative
Length = 1015
Score = 152 bits (385), Expect = 3e-35
Identities = 207/894 (23%), Positives = 413/894 (46%), Gaps = 131/894 (14%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRK------VAIE 72
+ LK+ + A+ + ++ ++ NL E + + K++ E +++ + +
Sbjct: 121 KSLKEDIAAKITEIKAINENLEKMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLT 180
Query: 73 GKLE-ISNTFAALENEVSALIS--ENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALR 129
KL+ ++N + ++ E +LI E K + I Q KI ++ E R ++
Sbjct: 181 EKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIE 240
Query: 130 QAVKILEKRIENLESENKKL--KKDIQEEQAQRKIEI-EGKLEKSNAFAALENEVSALKS 186
+ ++ L+K I +LE +++ K D +++ + +I + + KLE A A + V+ + S
Sbjct: 241 KNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLE--TATTANDENVNKI-S 297
Query: 187 ENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKF 246
E K ++++ E A K ++ +LE LE ALK E K+ ++ + +E+ Q
Sbjct: 298 ELTKTREELEAELAAYK-NLKNELETK-----LETSEKALK-EVKENEEHLKEEKIQ--- 347
Query: 247 CDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEI 306
L+K+ + + N+LR ++ LEK E+L ++ KK ++ I + Q EI
Sbjct: 348 ---LEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEI------ 398
Query: 307 SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNA----FAALENEVSAL 362
+ L +E+++ + EN+ +KK E + + K E SN AL ++ L
Sbjct: 399 ----SQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKEL 454
Query: 363 KSENKKLKQDILEE----QAQGKFCDQLKKKC----EKVVEGRNALRQAVKILEKGIENL 414
K +N+ + +LE +++ +L+ +C ++V E + L+ + K +E L
Sbjct: 455 KKKNETNEASLLESIKSIESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLE-L 513
Query: 415 ESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQI 474
+ E++K+K+++ + + KI++E +S A E+E+S LK S++ +K+ E+ ++
Sbjct: 514 QKESEKIKEELDAKTTELKIQLEKVTNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKL 573
Query: 475 KVAIEEKLEISNAFAALENE------------VSALKSEIAALQQKCGAGSRE-GNGDVE 521
K I+ K + L NE ++ L+ E+ LQ + ++E N E
Sbjct: 574 KNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSE 633
Query: 522 VLKAGISD---TEKEVNTLK----KELVEKEKIVADSERKTAVD-----------ERKKA 563
+ K +S+ E++ NT+K + L K+KI + E+ +++ E+ +A
Sbjct: 634 LEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDSKRDLESLKEQLRA 693
Query: 564 AAEAR-KLLEAAKKI----APEKAVIPEPANCCSKCD--------ELKKKCEKVAVGRNA 610
A E++ K+ E KK+ + EKA + + K + ELK E +
Sbjct: 694 AQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEK 753
Query: 611 LRQAVKILEKGIENLESENKKL----------------------KKENEVSALKSEISAL 648
L Q+ K E+ I+NL+ E L K +E+ +K E++
Sbjct: 754 LEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSSSELETVKQELNNA 813
Query: 649 QQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKE--HVEEERIVADSERKTAVDERKNA 706
Q+K A E VLK+ + D ++E+ + E +EE+ + S K E +
Sbjct: 814 QEKIRVNAEENT----VLKSKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDST 869
Query: 707 AAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVN-----ERKMKLAFELSKTKEATK 761
+A+K E + + + + ++++ + + LE + N E+ K + K ++
Sbjct: 870 QQKAQKSEEESRAEVRKFQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDTVKKTTDSQ 929
Query: 762 RFEAEKKKLLVEKINAE-SKIKKAQE-RSE-SELDKKTADMEKQQAEEQKKLAE 812
R E EK ++ + AE SK+K+A E RSE +L D++++ A+ + KL +
Sbjct: 930 RQEIEKLAKELDNLKAENSKLKEANEDRSEIDDLMLLVTDLDEKNAKYRSKLKD 983
Score = 133 bits (335), Expect = 2e-29
Identities = 199/862 (23%), Positives = 391/862 (45%), Gaps = 116/862 (13%)
Query: 42 LEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQD 101
L++ LE+E K ++ D +E Q + +E K + N A LE + S + + +K
Sbjct: 7 LKENFSILETELKNVR-DSLDEMTQLRDVLETK-DKENQTALLEYK-STIHKQEDSIKT- 62
Query: 102 ILEEQAQGKICDQLKKCE----KVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQ 157
LE++ + I Q KK E K+ + AL + ++ +E+ +NL+ E K + Q+E
Sbjct: 63 -LEKELE-TILSQKKKAEDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNVNHQKET 120
Query: 158 AQRKIEIEGKLEKSNA----FAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEIS 213
K +I K+ + A ++ + + L E + + K+++E +++ + +++
Sbjct: 121 KSLKEDIAAKITEIKAINENLEKMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLT 180
Query: 214 NAFAALENEVSALKSENKKLKQDILDEQAQGKF-CDRLKKKCEKVVEGRNALRQAVKILE 272
+L N +++EN+ L + + + + + L+ K + + + + + +E
Sbjct: 181 EKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIE 240
Query: 273 KGIENLE---SENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKK 329
K IE L+ S+ ++ K++I + K E E ++ + E +A + ++ + K
Sbjct: 241 KNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLK-----EKLETATTANDENVNK 295
Query: 330 DILEEQAQRKVAMEGKLEISNAFAALENEV-SALKSENKKLKQDILEEQAQGKFCDQLKK 388
+ E + + +E +L A+ L+NE+ + L++ K LK+ E+ + QL+K
Sbjct: 296 --ISELTKTREELEAELA---AYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEK 350
Query: 389 KCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEI-----------E 437
+ + + N+LR ++ LEK E+L ++ KK ++ I ++ Q EI +
Sbjct: 351 EATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQ 410
Query: 438 GKLEISNAFAALENEVSALKS---ESTKLKKDILEE-QAQIKVAIEEKLEISNAFAALEN 493
I LE EV A+KS E + LKK ++ QIK +++K E + A+L
Sbjct: 411 ENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIK-ELKKKNETNE--ASLLE 467
Query: 494 EVSALKSE---IAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVAD 550
+ +++SE I LQ +C +E + + LKA K + K E EKI +
Sbjct: 468 SIKSIESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQK----ESEKIKEE 523
Query: 551 SERKTA--------VDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCE 602
+ KT V KA ++ L KK + E+ E ++L+K
Sbjct: 524 LDAKTTELKIQLEKVTNLSKAKEKSESELSRLKKTSSEERKNAE--------EQLEKLKN 575
Query: 603 KVAVGRNALRQAVKILEKG-----------IENLESENKKLKKENEVSA-----LKSEIS 646
++ + A + K+L +G I LE E +L+ ENE+ A +SE+
Sbjct: 576 EIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELE 635
Query: 647 ALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERK-TAVDERKN 705
+ E ++ L+ I K ++ R ++ + ER DS+R ++ E+
Sbjct: 636 KVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIER---DSKRDLESLKEQLR 692
Query: 706 AAAEAR-KLLEAPKKIAAEVEKQIAKVELRQVHLEK-----QVNERKMKLAFEL-----S 754
AA E++ K+ E KK+ E K+ A++E + ++K + NE ++K + E
Sbjct: 693 AAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDE 752
Query: 755 KTKEATKRFEAEKKKLLVEKINAESKIKKAQE-------------RSESELDKKTADMEK 801
K +++ K E + K L EK + S+I ++++ +S SEL+ T E
Sbjct: 753 KLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSSSELE--TVKQEL 810
Query: 802 QQAEEQKKLAEDKLLLLGDSLQ 823
A+E+ ++ ++ +L L+
Sbjct: 811 NNAQEKIRVNAEENTVLKSKLE 832
Score = 130 bits (327), Expect = 2e-28
Identities = 173/843 (20%), Positives = 356/843 (41%), Gaps = 95/843 (11%)
Query: 46 IENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEE 105
I E K L+K+++ +Q+K A +G ++ AL E+ A + EN K ++ +E
Sbjct: 53 IHKQEDSIKTLEKELETILSQKKKAEDGINKMGKDLFALSREMQA-VEENCK---NLQKE 108
Query: 106 QAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIE 165
+ + + Q K+ + + E A +K + + +E ++ + L K+ +E ++ +E +
Sbjct: 109 KDKSNVNHQ-KETKSLKEDIAAKITEIKAINENLEKMKIQCNNLSKE-KEHISKELVEYK 166
Query: 166 GKLEK-SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVS 224
+ + N A L ++ +L + K ++ E ++ K E K E S + L+N++
Sbjct: 167 SRFQSHDNLVAKLTEKLKSLANNYKDMQA---ENESLIKAVEESKNESSIQLSNLQNKID 223
Query: 225 ALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKK 284
++ E + + ++ + K ++LKK + + + + + + + ES+
Sbjct: 224 SMSQEKENFQ---IERGSIEKNIEQLKKTISDLEQTKEEI---ISKSDSSKDEYESQISL 277
Query: 285 LKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEG 344
LK+ ++ + E++ LE E++A K+ +L+ + + K E
Sbjct: 278 LKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKEN 337
Query: 345 KLEISNAFAALENEVSALKSENKKLKQDILE-EQAQGKFCDQLKKKCEKVVEGRNALRQA 403
+ + LE E + K + L+ ++ E+ QLKK E++ +
Sbjct: 338 EEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEE 397
Query: 404 VKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKL 463
+ L I + + EN+ +KK E + + K E SN ++E+ AL + +L
Sbjct: 398 ISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNL---KKSEIDALNLQIKEL 454
Query: 464 KKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVL 523
KK +A + +I+ + L++E + + E++ L+ K A + + +E+
Sbjct: 455 KKKNETNEASLLESIKSIESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQ 514
Query: 524 KAG--------ISDTEKEVNTLKKELVEKEKIVADSE----RKTAVDERKKAAAEARKLL 571
K TE ++ K + K K ++SE +KT+ +ERK A + KL
Sbjct: 515 KESEKIKEELDAKTTELKIQLEKVTNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLK 574
Query: 572 EAAK----KIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLES 627
+ E+ ++ E ++ ++ E +K + L+ ++ K I+N S
Sbjct: 575 NEIQIKNQAFEKERKLLNEGSSTITQ--EYSEKINTLEDELIRLQNENELKAKEIDNTRS 632
Query: 628 ENKKL---------KKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVN 678
E +K+ +K+N + +L+ EI + + K + E L + D+K+++
Sbjct: 633 ELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKI-------TRNDEKLLSIERDSKRDLE 685
Query: 679 RLKKE--HVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVE----------- 725
LK++ +E + + K +E AE K E KK+ + +E
Sbjct: 686 SLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSME 745
Query: 726 ---KQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVE--------- 773
K K+E + E+ + + + + +S+ E+ K E K KL +E
Sbjct: 746 TIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSSSELET 805
Query: 774 ------------KINAESK--IKKAQERSESELDKKTADMEKQQAEEQKKLAEDKLLLLG 819
++NAE +K E E EL K A+++ Q E+K+L +L L
Sbjct: 806 VKQELNNAQEKIRVNAEENTVLKSKLEDIERELKDKQAEIKSNQ--EEKELLTSRLKELE 863
Query: 820 DSL 822
L
Sbjct: 864 QEL 866
Score = 129 bits (323), Expect = 5e-28
Identities = 174/757 (22%), Positives = 327/757 (42%), Gaps = 94/757 (12%)
Query: 16 SKCEELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKL 75
S+ LK+K E + + L K E LE+E K E + + + + +
Sbjct: 273 SQISLLKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALK 332
Query: 76 EISNTFAALENEVSALISENKKLKQDI------LE--EQAQGKICDQLKKCEKVVEGR-N 126
E+ L+ E L E + KQ + LE E+ + QLKK E+ + +
Sbjct: 333 EVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKER 392
Query: 127 ALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKS 186
+ + L I + + EN+ +KK E + + K E+SN ++E+ AL
Sbjct: 393 QYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSN---LKKSEIDALNL 449
Query: 187 ENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKF 246
+ K+LKK +A +++ + L++E + + E +L+ + + +
Sbjct: 450 QIKELKKKNETNEASLLESIKSIESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSK 509
Query: 247 CDRLKKKCEKVVEGRNALRQAVKI-------LEKGIENLESENKKLKKDIQEE------- 292
L+K+ EK+ E +A +KI L K E ESE +LKK EE
Sbjct: 510 YLELQKESEKIKEELDAKTTELKIQLEKVTNLSKAKEKSESELSRLKKTSSEERKNAEEQ 569
Query: 293 ---------------HAQRKVEIEGKLEISNAFA----ALENEVSALKSENKKLKKDILE 333
+RK+ EG I+ ++ LE+E+ L++EN+ K+I
Sbjct: 570 LEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDN 629
Query: 334 EQAQ-RKVAM---EGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKK 389
+++ KV++ E E N +L++E+ + K + + + +L + K+
Sbjct: 630 TRSELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDS------KRD 683
Query: 390 CEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAAL 449
E + E A +++ +E+G++ LE E+ K K ++++ + K ++E +E + L
Sbjct: 684 LESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMK-KLESTIESNE--TEL 740
Query: 450 ENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALK---------- 499
++ + ++ KL++ + IK EK ++ + E ++ LK
Sbjct: 741 KSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSS 800
Query: 500 SEIAALQQKCGAGSREGNGDVE---VLKAGISDTEKEVN----TLKKELVEKEKIVA--- 549
SE+ ++Q+ + + E VLK+ + D E+E+ +K EKE + +
Sbjct: 801 SELETVKQELNNAQEKIRVNAEENTVLKSKLEDIERELKDKQAEIKSNQEEKELLTSRLK 860
Query: 550 ------DSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPA--NCCSKCDELKKKC 601
DS ++ A +++ AE RK + K EKA++ E + +K K+
Sbjct: 861 ELEQELDSTQQKAQKSEEESRAEVRK-FQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDE 919
Query: 602 EKVAVGRNALRQAVKILEKGIENLESENKKLKKEN----EVSALKSEISALQQKCGAGAR 657
+ V ++ RQ ++ L K ++NL++EN KLK+ N E+ L ++ L +K A R
Sbjct: 920 DTVKKTTDSQRQEIEKLAKELDNLKAENSKLKEANEDRSEIDDLMLLVTDLDEK-NAKYR 978
Query: 658 EGNGD--VEVLKAGISDTKKEVNRLKKEHVEEERIVA 692
D VE+ D ++E + E EEE VA
Sbjct: 979 SKLKDLGVEISSDEEDDEEEEDDEEDDEEDEEEGQVA 1015
Score = 117 bits (294), Expect = 1e-24
Identities = 149/642 (23%), Positives = 303/642 (46%), Gaps = 88/642 (13%)
Query: 213 SNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILE 272
+++ ++L+ S L++E K ++ D LDE Q + K K E + AL + +
Sbjct: 1 NSSHSSLKENFSILETELKNVR-DSLDEMTQLRDVLETKDK-----ENQTALLEYKSTIH 54
Query: 273 KGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKD-- 330
K +++ K L+K+++ +Q+K +G ++ AL E+ A++ K L+K+
Sbjct: 55 KQEDSI----KTLEKELETILSQKKKAEDGINKMGKDLFALSREMQAVEENCKNLQKEKD 110
Query: 331 ---ILEEQAQRKVAMEGKLEISNAFAALEN------EVSALKSENKKLKQDILEEQAQGK 381
+ ++ + + + +I+ A EN + + L E + + ++++E +++ +
Sbjct: 111 KSNVNHQKETKSLKEDIAAKITEIKAINENLEKMKIQCNNLSKEKEHISKELVEYKSRFQ 170
Query: 382 FCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLE 441
D L K L + +K L +++++EN+ L K ++E + + I++
Sbjct: 171 SHDNLVAK----------LTEKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSN--- 217
Query: 442 ISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSE 501
+ N ++ E + E ++K+I + + I + K EI + + ++E +S+
Sbjct: 218 LQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEY---ESQ 274
Query: 502 IAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERK 561
I+ L++K + + +V IS+ K L+ EL + + +E +T ++ +
Sbjct: 275 ISLLKEKLETATTANDENVNK----ISELTKTREELEAELAAYKNL--KNELETKLETSE 328
Query: 562 KAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKG 621
KA E ++ E K+ EK +L+K+ + N+LR ++ LEK
Sbjct: 329 KALKEVKENEEHLKE---EKI-------------QLEKEATETKQQLNSLRANLESLEKE 372
Query: 622 IENLESENKKLKKE---------NEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISD 672
E+L ++ KK +++ E+S L EI++ QQ+ ++ N ++E +
Sbjct: 373 HEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQE-NESIKKKNDELEGEVKAMKS 431
Query: 673 TKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVE 732
T +E + LKK ++ + +K KN EA LLE+ K I +E K I +++
Sbjct: 432 TSEEQSNLKKSEIDALNLQIKELKK------KNETNEA-SLLESIKSIESETVK-IKELQ 483
Query: 733 LRQVHLEKQVNERKMKL-AFELSKTKEATKRFEAEKKKLLVEKINAESKIK--------K 783
EK+V+E + KL A E +K + E+EK K ++ E KI+ K
Sbjct: 484 DECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKVTNLSK 543
Query: 784 AQERSESELD--KKTADMEKQQAEEQKKLAEDKLLLLGDSLQ 823
A+E+SESEL KKT+ E++ AEEQ + ++++ + + +
Sbjct: 544 AKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFE 585
Score = 62.4 bits (150), Expect = 6e-08
Identities = 76/314 (24%), Positives = 135/314 (42%), Gaps = 33/314 (10%)
Query: 2 ASEKAVIPEPANCCSKCE--------ELKKKCEQVVVGRNALRQAVKILEKGIENLESEN 53
+ EKA + + K E ELK E + L Q+ K E+ I+NL+ E
Sbjct: 713 SKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEK 772
Query: 54 KKL-------KKDIQEEQAQRKVAIEGKLEISNTFAALEN---EVSALISENKKLKQDIL 103
L +KDI+E +++ ++ + E+ L N ++ EN LK +
Sbjct: 773 SDLISRINESEKDIEELKSKLRIEAKSSSELETVKQELNNAQEKIRVNAEENTVLKSKL- 831
Query: 104 EEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQ-RKI 162
E + ++ D+ + + E + L +K LE + L+S +K +K +E +A+ RK
Sbjct: 832 -EDIERELKDKQAEIKSNQEEKELLTSRLKELE---QELDSTQQKAQKSEEESRAEVRKF 887
Query: 163 EIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENE 222
++E K + LE + + L ++ + K+D E +K + EI L E
Sbjct: 888 QVE-KSQLDEKAMLLETKYNDLVNKEQAWKRD---EDTVKKTTDSQRQEIEK----LAKE 939
Query: 223 VSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQ-AVKILEKGIENLESE 281
+ LK+EN KLK+ D + EK + R+ L+ V+I ++ E E
Sbjct: 940 LDNLKAENSKLKEANEDRSEIDDLMLLVTDLDEKNAKYRSKLKDLGVEISSDEEDDEEEE 999
Query: 282 NKKLKKDIQEEHAQ 295
+ + + EE Q
Sbjct: 1000 DDEEDDEEDEEEGQ 1013
>ref|NP_504584.1| immunoglobulin-like and fibronectin, type III and M protein repeat
(5G632) [Caenorhabditis elegans]
Length = 3484
Score = 149 bits (377), Expect = 3e-34
Identities = 215/841 (25%), Positives = 376/841 (44%), Gaps = 126/841 (14%)
Query: 4 EKAVIPEPANCCSKCEELKKKC---EQVVVGRNALRQAVKILEKGIENLESENKKLKKDI 60
EKA PE S+ EE+ KK ++ +++ Q +L+ ++ + K
Sbjct: 640 EKAAGPETKKDVSEIEEVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSK 699
Query: 61 QEEQAQRKVAIEGKLE-ISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE 119
+ + Q KVA + KLE ++T +E E ++ + K K + + Q +
Sbjct: 700 KTTEDQTKVATDSKLEKAADTTKQIETET--VVDDKSKKKVLKKKTEKSDSFISQKSETP 757
Query: 120 KVVEG-RNALRQAVKILE-------KRIE-NLESENKKLKKDIQEEQAQRKIEIEGKLEK 170
VVE + A +A KI E K ++ NL+ E + K I +E+ KIE E ++K
Sbjct: 758 PVVEPTKPAESEAQKIAEVNKAKKQKEVDDNLKREAEVAAKKIADEKL--KIEAEANIKK 815
Query: 171 SNAFAALENEVSALKSENKKLKKDILEEQ-AQRKVAMEGKLEISNAFAALENEVSALKSE 229
+ A + + K E KL+ +++ ++ A K+ +E + +I A E A+K +
Sbjct: 816 TAEVEAAKKQKE--KDEQLKLETEVVSKKSAAEKLELEKQAQIKKAA-----EADAVKKQ 868
Query: 230 NKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDI 289
K+L + E A+ D+LK + E + + ++VK E E + K +K +
Sbjct: 869 -KELNEKNKLEAAKKSAADKLKLEEESAAKSKKVSEESVKFGE------EKKTKAGEKTV 921
Query: 290 Q-EEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEI 348
Q E K I+ K +V A + ++ KK I++++ ++ + I
Sbjct: 922 QVESEPTSKKTIDTK------------DVGATEPADETPKKKIIKKKTEKSDS-----SI 964
Query: 349 SNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILE 408
S A +VS K +++ K + E Q + D+ KK+ E + + A K +
Sbjct: 965 SQKSATDSEKVSKQKEQDEPTKPAVSETQMVTE-ADKSKKQKETDEKLKLDAEIAAKTKQ 1023
Query: 409 KGIENLESE-NKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDI 467
+ E + + +K+KK +++ A+++ E+ KL+ LE+E++ K+ + KLK
Sbjct: 1024 EADEKSKLDAQEKIKKVSEDDAARKEKELNDKLK-------LESEIATKKASADKLK--- 1073
Query: 468 LEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGI 527
LEEQAQ K A E + A + + LK + A +K A E ++ KA
Sbjct: 1074 LEEQAQAKKAAEVE-----AAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAG 1128
Query: 528 SDTEKEVNTLKKELVEKEKIVADSERKTAVD----ERKKAAAEARKLLEAAKKIAPEKAV 583
+D K+ +KEL EK K+ A+ +K+A E + AA + + E AK A KA
Sbjct: 1129 ADAVKK----QKELDEKNKLEAN--KKSAAGKLKIEEESAAKSKQTVEEQAKLDAQTKAK 1182
Query: 584 IPEPANCCSKCDELKKKCE-KVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALK 642
E K ++ K+ E K V ++ +K KK +K + + K
Sbjct: 1183 TAEKQTKLEKDEKSTKESESKETVDEKPKKKVLK-------------KKTEKSDSSISQK 1229
Query: 643 SEISALQQKCGAGAREGNGDVEVLKAGISDTKK--EVNRLKKEHVEEERIVADSERKTAV 700
SE S + AG E S+T+K + R +KE E++++ A+ K +
Sbjct: 1230 SETSKTVVE-SAGPSE------------SETQKVADAARKQKETDEKQKLEAEITAKKSA 1276
Query: 701 DERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEAT 760
DE+ AE++ K+ A+VE + EK + ++KL E + K A
Sbjct: 1277 DEKSKLEAESKL-------------KKAAEVEAAKKQKEK---DEQLKLDTEAASKKAAA 1320
Query: 761 KRFEAEKKKLL--VEKINAESKIKKAQE--RSESELDKKTADMEKQQAEEQKKLAEDKLL 816
++ E EK+ + +++A K K+ +E R ESE K AD EK + EEQKK A + L
Sbjct: 1321 EKLELEKQSHIKKAAEVDAVKKQKELEEKQRLESEAATKKADAEKLKLEEQKKKAAEIAL 1380
Query: 817 L 817
+
Sbjct: 1381 I 1381
Score = 112 bits (279), Expect = 6e-23
Identities = 185/787 (23%), Positives = 341/787 (42%), Gaps = 103/787 (13%)
Query: 83 ALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENL 142
A ++E ++ K+ + ++E + K D+ K E+ +N + V + EK
Sbjct: 590 AKKSEKKDEVTAEKQSTEALIESKK--KEVDESKISEQQPSDKNK-SEVVGVPEK----- 641
Query: 143 ESENKKLKKDIQE-EQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEE--- 198
+ + KKD+ E E+ +K I+ K EKS++ + ++ V ++K D+ ++
Sbjct: 642 -AAGPETKKDVSEIEEVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSKK 700
Query: 199 --QAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEK 256
+ Q KVA + KLE A + + + ++D++++ K + +K +
Sbjct: 701 TTEDQTKVATDSKLE------------KAADTTKQIETETVVDDKSKKKVLKKKTEKSDS 748
Query: 257 VVEGRNALRQAV---KILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAAL 313
+ ++ V K E + + NK K+ +++ +R+ E+ K +I++ +
Sbjct: 749 FISQKSETPPVVEPTKPAESEAQKIAEVNKAKKQKEVDDNLKREAEVAAK-KIADEKLKI 807
Query: 314 ENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDI 373
E E + K+ + K E+ Q K LE EV + KS +KL+
Sbjct: 808 EAEANIKKTAEVEAAKKQKEKDEQLK---------------LETEVVSKKSAAEKLE--- 849
Query: 374 LEEQAQGKFC---DQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQA 430
LE+QAQ K D +KK +K + +N L A K ++ LE E+ K + EE
Sbjct: 850 LEKQAQIKKAAEADAVKK--QKELNEKNKLEAAKKSAADKLK-LEEESAAKSKKVSEESV 906
Query: 431 QRKIEIEGKLEISNAFAALENEVSALKSESTK-LKKDILEEQAQIKVAIEEKLEISNAFA 489
K E K + +E+E ++ K+ TK + ++ K I++K E S++
Sbjct: 907 --KFGEEKKTKAGEKTVQVESEPTSKKTIDTKDVGATEPADETPKKKIIKKKTEKSDSSI 964
Query: 490 ALENEVSALKSEIAALQQKCGAGSREGNGDVE-VLKAGISDTEKEVNT---LKKELVEKE 545
+ + SA SE + Q++ ++ + + V +A S +KE + L E+ K
Sbjct: 965 S---QKSATDSEKVSKQKEQDEPTKPAVSETQMVTEADKSKKQKETDEKLKLDAEIAAKT 1021
Query: 546 KIVADSERKTAVDERKKAAAE---ARKLLE-----------AAKKIAPEKAVIPEPANC- 590
K AD + K E+ K +E ARK E A KK + +K + E A
Sbjct: 1022 KQEADEKSKLDAQEKIKKVSEDDAARKEKELNDKLKLESEIATKKASADKLKLEEQAQAK 1081
Query: 591 -CSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENK-KLKKENEVSALKSEISAL 648
++ + KK+ EK + A K + E LE E + ++KK A+K +
Sbjct: 1082 KAAEVEAAKKQKEKDEQLKLDTEAASK--KAAAEKLELEKQAQIKKAAGADAVKKQKELD 1139
Query: 649 QQ-KCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAA 707
++ K A + G +++ + + +K+ V K + + A+ + K DE+
Sbjct: 1140 EKNKLEANKKSAAGKLKIEEESAAKSKQTVEEQAKLDAQTKAKTAEKQTKLEKDEKSTKE 1199
Query: 708 AEARKLL-EAPKK--IAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFE 764
+E+++ + E PKK + + EK + + + K V E E K +A ++ +
Sbjct: 1200 SESKETVDEKPKKKVLKKKTEKSDSSISQKS-ETSKTVVESAGPSESETQKVADAARKQK 1258
Query: 765 A--EKKKLLVE-----------KINAESKIKKAQERSESELDKKTADMEKQQAE-EQKKL 810
EK+KL E K+ AESK+KKA E ++ K+ + K E KK
Sbjct: 1259 ETDEKQKLEAEITAKKSADEKSKLEAESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKA 1318
Query: 811 AEDKLLL 817
A +KL L
Sbjct: 1319 AAEKLEL 1325
Score = 75.5 bits (184), Expect = 7e-12
Identities = 169/816 (20%), Positives = 318/816 (38%), Gaps = 109/816 (13%)
Query: 32 RNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLE--ISNTFAALENEVS 89
R L++ +++E ++ + KK KK + +R+ +L I F + ++
Sbjct: 185 RRRLQRGRRVMEASSDSELDDAKKRKKRRIKRVVERRNPNAPRLTQLIPPRFDKILSDHD 244
Query: 90 ALISENKKLKQDILEEQA-------QGKICDQLKKCEKVVEGRNALRQAVKILEKRIENL 142
A+ EN + + L E GK+ D V + +R+ IL
Sbjct: 245 AIEGENVVMMVETLGEPEPQVRFYRDGKLIDDGSGDRMEVRHEDEMRKHWLIL------- 297
Query: 143 ESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQR 202
K + KD + E A + I + G+ A ++V SE + ++E
Sbjct: 298 ----KDICKDEEAEYACQAINVAGE-------AWCFSDVVVHMSEESRDDDKSVDEVDDS 346
Query: 203 KVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRN 262
V E K + ++ S K++ K +K+ E Q + ++K +V + ++
Sbjct: 347 TVLEEKKDD--------GDDKSKPKTKKKIIKKKETPESEQVTAAEPEQQKISEV-DVQS 397
Query: 263 ALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKS 322
V +K ++ K KKD + + + E E E + N+ ++ KS
Sbjct: 398 VAETEVGAKKKPDAEKPTDLSKAKKDSKSKKSD---EPEASTEEKSTTEKPTNDKTSKKS 454
Query: 323 ENKKL---KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQD----ILE 375
KK KK++ + + K +E K + S ++ E S+ ++ KK KQ +
Sbjct: 455 AEKKTVKPKKEVTGKPLEAKKPVEDKKDASQPSSSKE---SSPPTDGKKKKQIPKALFIP 511
Query: 376 EQAQGKFCDQLKKKCEK----VVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQ 431
++ +F D E + GR A L +E L + ++ E A+
Sbjct: 512 DEISSRFGDPSTMHSETNITTTIRGREGSADAKTPL---VEPLSAS-----VSMKVESAK 563
Query: 432 RKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIE-EKLEISNAFAA 490
K E K + ++ ++ K ++ E+ + IE +K E+ + +
Sbjct: 564 EKAEFSFKRRSETPDDKSRKKEGLPPAKKSEKKDEVTAEKQSTEALIESKKKEVDESKIS 623
Query: 491 LENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVAD 550
+ KSE+ + +K A E DV + I + K+ T+KK+ + + ++
Sbjct: 624 EQQPSDKNKSEVVGVPEK--AAGPETKKDV----SEIEEVPKK-KTIKKKTEKSDSSISQ 676
Query: 551 SER--KTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGR 608
K A D++ K+ + + +KK ++ + + D K+ + V
Sbjct: 677 KSNVLKPADDDKSKSD----DVTDKSKKTTEDQTKVATDSKLEKAADTTKQIETETVVDD 732
Query: 609 NALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKA 668
+ ++ +K KK +K + + KSE + + E EV KA
Sbjct: 733 KSKKKVLK-------------KKTEKSDSFISQKSETPPVVEPTKPAESEAQKIAEVNKA 779
Query: 669 GISDTKKEVN-RLKKEHVEEERIVADSERKTAVDERKNAAAE---ARKLLEAPKKIAAEV 724
+KEV+ LK+E + +AD + K + AE A+K E +++ E
Sbjct: 780 ---KKQKEVDDNLKREAEVAAKKIADEKLKIEAEANIKKTAEVEAAKKQKEKDEQLKLET 836
Query: 725 EKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKA 784
E K ++ LEKQ +K A + K KE EK KL K +A K+K
Sbjct: 837 EVVSKKSAAEKLELEKQAQIKKAAEADAVKKQKELN-----EKNKLEAAKKSAADKLK-- 889
Query: 785 QERSESELDKKTADMEKQQAEEQKKLAEDKLLLLGD 820
L++++A K+ +EE K E+K G+
Sbjct: 890 -------LEEESAAKSKKVSEESVKFGEEKKTKAGE 918
Score = 45.8 bits (107), Expect = 0.006
Identities = 81/358 (22%), Positives = 140/358 (38%), Gaps = 69/358 (19%)
Query: 521 EVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKK---- 576
+++K + ++V + E + ++ S +T V +KK AE L AKK
Sbjct: 367 KIIKKKETPESEQVTAAEPEQQKISEVDVQSVAETEVGAKKKPDAEKPTDLSKAKKDSKS 426
Query: 577 --------IAPEKAVIPEPAN--CCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLE 626
EK+ +P N K E K K V L + +K +
Sbjct: 427 KKSDEPEASTEEKSTTEKPTNDKTSKKSAEKKTVKPKKEVTGKPLEAKKPVEDKKDASQP 486
Query: 627 SENK--------KLKKE--------NEVSALKSEISALQQKCG----AGAREGNGD---- 662
S +K K KK+ +E+S+ + S + + REG+ D
Sbjct: 487 SSSKESSPPTDGKKKKQIPKALFIPDEISSRFGDPSTMHSETNITTTIRGREGSADAKTP 546
Query: 663 -VEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDE--RKNAAAEARKLLEAPKK 719
VE L A +S +K E +E+ + R D+ RK K E +
Sbjct: 547 LVEPLSASVS--------MKVESAKEKAEFSFKRRSETPDDKSRKKEGLPPAKKSEKKDE 598
Query: 720 IAAEVEKQIAKVELRQVHLEKQVNERKM-------KLAFELSKTKEATKRFEAEKKKLLV 772
+ AE + A +E + +K+V+E K+ K E+ E E +K +
Sbjct: 599 VTAEKQSTEALIESK----KKEVDESKISEQQPSDKNKSEVVGVPEKAAGPETKKDVSEI 654
Query: 773 EKINAESKIKKAQERSESELDKKT-----ADMEKQQAEE----QKKLAEDKLLLLGDS 821
E++ + IKK E+S+S + +K+ AD +K ++++ KK ED+ + DS
Sbjct: 655 EEVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSKKTTEDQTKVATDS 712
Score = 40.4 bits (93), Expect = 0.24
Identities = 95/408 (23%), Positives = 169/408 (41%), Gaps = 85/408 (20%)
Query: 337 QRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEG 396
++KV LEI+N ++ K K L E G++ Q+ V
Sbjct: 2763 RKKVGDSDWLEIAN-------------TDRNKFKDRSLTES--GEYVYQVTATGIHAVSS 2807
Query: 397 RNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKI--EIEGKLEISNAFAALENEVS 454
+ VKIL G E S+ +K K D + ++++K EI + ++ + A+ E+
Sbjct: 2808 PSEETNPVKILVPGSEMPASKTEK-KTDAAKSESEQKSAEEIVAEKQVDQSQAS-ESTTE 2865
Query: 455 ALKSESTK--LKKDILEEQAQIKVA-IEEKLEISNAFAALENEVSALKSEIAALQQKCGA 511
A++ + TK +KK + E + + + ++EKL+ A +++E
Sbjct: 2866 AVEEKKTKKVVKKKVAENKGEETLQEVKEKLKKGKAVEKVQDE----------------- 2908
Query: 512 GSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLL 571
SR G+ L+A SD E T +K + ++ +SE+ E+K +A+ L
Sbjct: 2909 -SRRGS-----LQAS-SDNESVTTTSEKR--SEAELEKNSEKSA---EKKSTSAD----L 2952
Query: 572 EAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKK 631
EAA K EK+ + ++ KK +KVA +KG+ + +
Sbjct: 2953 EAADKAETEKSETGKETT-----EKKKKVVKKVA-------------KKGLVKADKSKIE 2994
Query: 632 LK--KENEVSALKSEIS-ALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEE 688
L KE E+SA +E +++ K A + + V G+S K + V
Sbjct: 2995 LTAGKEGEISAQVAETGVSVEWKKDGKALDASYTV-TSTGGVSTVKIPI-----VDVNTS 3048
Query: 689 RIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQV 736
+ + + DE + + A KL E PK E E+ I +V++ V
Sbjct: 3049 GVFTCKVKSSEGDEEEVSIAVTVKLPEVPK---VEAEQSIVEVKVGDV 3093
Score = 37.0 bits (84), Expect = 2.6
Identities = 43/205 (20%), Positives = 88/205 (41%), Gaps = 14/205 (6%)
Query: 622 IENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAG----ISDTKKEV 677
I N + K + E +++A + E V++L G S T+K+
Sbjct: 2774 IANTDRNKFKDRSLTESGEYVYQVTATGIHAVSSPSEETNPVKILVPGSEMPASKTEKKT 2833
Query: 678 NRLKKEHVEE--ERIVADSE-RKTAVDERKNAAAEARKLLEAPKKIAAEVEK----QIAK 730
+ K E ++ E IVA+ + ++ E A E +K + KK AE + Q K
Sbjct: 2834 DAAKSESEQKSAEEIVAEKQVDQSQASESTTEAVEEKKTKKVVKKKVAENKGEETLQEVK 2893
Query: 731 VELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSES 790
+L++ ++V + + + + S E+ ++ + +EK + +S KK+
Sbjct: 2894 EKLKKGKAVEKVQDESRRGSLQASSDNESVTTTSEKRSEAELEKNSEKSAEKKSTSADLE 2953
Query: 791 ELDK---KTADMEKQQAEEQKKLAE 812
DK + ++ K+ E++KK+ +
Sbjct: 2954 AADKAETEKSETGKETTEKKKKVVK 2978
Score = 36.2 bits (82), Expect = 4.5
Identities = 63/280 (22%), Positives = 109/280 (38%), Gaps = 76/280 (27%)
Query: 527 ISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPE 586
+S +E N +K +V SE + E+K AA++ ++A++I EK V
Sbjct: 2805 VSSPSEETNPVKI-------LVPGSEMPASKTEKKTDAAKSESEQKSAEEIVAEKQVDQS 2857
Query: 587 PANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEIS 646
A+ + +KK +KV + A KG E L+ +KLKK V ++ E
Sbjct: 2858 QASESTTEAVEEKKTKKVVKKKVAEN-------KGEETLQEVKEKLKKGKAVEKVQDE-- 2908
Query: 647 ALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNA 706
+R G+ L+A + E + SE+++ + KN+
Sbjct: 2909 ---------SRRGS-----LQASS---------------DNESVTTTSEKRSEAELEKNS 2939
Query: 707 AAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAE 766
A K K +A++E A + K T + E
Sbjct: 2940 EKSAEK-----KSTSADLEA-----------------------ADKAETEKSETGKETTE 2971
Query: 767 KKKLLVEKINAESKIKKAQERSESELDK-KTADMEKQQAE 805
KKK +V+K+ + +K ++S+ EL K ++ Q AE
Sbjct: 2972 KKKKVVKKVAKKGLVK--ADKSKIELTAGKEGEISAQVAE 3009
>pir||T34418 hypothetical protein F12F3.3 - Caenorhabditis elegans
Length = 3488
Score = 149 bits (377), Expect = 3e-34
Identities = 215/841 (25%), Positives = 376/841 (44%), Gaps = 126/841 (14%)
Query: 4 EKAVIPEPANCCSKCEELKKKC---EQVVVGRNALRQAVKILEKGIENLESENKKLKKDI 60
EKA PE S+ EE+ KK ++ +++ Q +L+ ++ + K
Sbjct: 644 EKAAGPETKKDVSEIEEVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSK 703
Query: 61 QEEQAQRKVAIEGKLE-ISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE 119
+ + Q KVA + KLE ++T +E E ++ + K K + + Q +
Sbjct: 704 KTTEDQTKVATDSKLEKAADTTKQIETET--VVDDKSKKKVLKKKTEKSDSFISQKSETP 761
Query: 120 KVVEG-RNALRQAVKILE-------KRIE-NLESENKKLKKDIQEEQAQRKIEIEGKLEK 170
VVE + A +A KI E K ++ NL+ E + K I +E+ KIE E ++K
Sbjct: 762 PVVEPTKPAESEAQKIAEVNKAKKQKEVDDNLKREAEVAAKKIADEKL--KIEAEANIKK 819
Query: 171 SNAFAALENEVSALKSENKKLKKDILEEQ-AQRKVAMEGKLEISNAFAALENEVSALKSE 229
+ A + + K E KL+ +++ ++ A K+ +E + +I A E A+K +
Sbjct: 820 TAEVEAAKKQKE--KDEQLKLETEVVSKKSAAEKLELEKQAQIKKAA-----EADAVKKQ 872
Query: 230 NKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDI 289
K+L + E A+ D+LK + E + + ++VK E E + K +K +
Sbjct: 873 -KELNEKNKLEAAKKSAADKLKLEEESAAKSKKVSEESVKFGE------EKKTKAGEKTV 925
Query: 290 Q-EEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEI 348
Q E K I+ K +V A + ++ KK I++++ ++ + I
Sbjct: 926 QVESEPTSKKTIDTK------------DVGATEPADETPKKKIIKKKTEKSDS-----SI 968
Query: 349 SNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILE 408
S A +VS K +++ K + E Q + D+ KK+ E + + A K +
Sbjct: 969 SQKSATDSEKVSKQKEQDEPTKPAVSETQMVTE-ADKSKKQKETDEKLKLDAEIAAKTKQ 1027
Query: 409 KGIENLESE-NKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDI 467
+ E + + +K+KK +++ A+++ E+ KL+ LE+E++ K+ + KLK
Sbjct: 1028 EADEKSKLDAQEKIKKVSEDDAARKEKELNDKLK-------LESEIATKKASADKLK--- 1077
Query: 468 LEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGI 527
LEEQAQ K A E + A + + LK + A +K A E ++ KA
Sbjct: 1078 LEEQAQAKKAAEVE-----AAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAG 1132
Query: 528 SDTEKEVNTLKKELVEKEKIVADSERKTAVD----ERKKAAAEARKLLEAAKKIAPEKAV 583
+D K+ +KEL EK K+ A+ +K+A E + AA + + E AK A KA
Sbjct: 1133 ADAVKK----QKELDEKNKLEAN--KKSAAGKLKIEEESAAKSKQTVEEQAKLDAQTKAK 1186
Query: 584 IPEPANCCSKCDELKKKCE-KVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALK 642
E K ++ K+ E K V ++ +K KK +K + + K
Sbjct: 1187 TAEKQTKLEKDEKSTKESESKETVDEKPKKKVLK-------------KKTEKSDSSISQK 1233
Query: 643 SEISALQQKCGAGAREGNGDVEVLKAGISDTKK--EVNRLKKEHVEEERIVADSERKTAV 700
SE S + AG E S+T+K + R +KE E++++ A+ K +
Sbjct: 1234 SETSKTVVE-SAGPSE------------SETQKVADAARKQKETDEKQKLEAEITAKKSA 1280
Query: 701 DERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEAT 760
DE+ AE++ K+ A+VE + EK + ++KL E + K A
Sbjct: 1281 DEKSKLEAESKL-------------KKAAEVEAAKKQKEK---DEQLKLDTEAASKKAAA 1324
Query: 761 KRFEAEKKKLL--VEKINAESKIKKAQE--RSESELDKKTADMEKQQAEEQKKLAEDKLL 816
++ E EK+ + +++A K K+ +E R ESE K AD EK + EEQKK A + L
Sbjct: 1325 EKLELEKQSHIKKAAEVDAVKKQKELEEKQRLESEAATKKADAEKLKLEEQKKKAAEIAL 1384
Query: 817 L 817
+
Sbjct: 1385 I 1385
Score = 112 bits (280), Expect = 5e-23
Identities = 194/831 (23%), Positives = 354/831 (42%), Gaps = 117/831 (14%)
Query: 41 ILEKGIENLESENKKLKKDIQEEQAQRKVAIEG--KLEISNTFAALENEVSALISENKKL 98
++E E E K+ + + ++++++K + K E + A + ALI KK
Sbjct: 562 LVESAKEKAEFSFKR-RSETPDDKSRKKEGLPPAKKSEKKDEVTAEKQSTEALIESKKK- 619
Query: 99 KQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQE-EQ 157
E + KI +Q + E V + EK + + KKD+ E E+
Sbjct: 620 ------EVDESKISEQQPSDKNKSE-------VVGVPEK------AAGPETKKDVSEIEE 660
Query: 158 AQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEE-----QAQRKVAMEGKLEI 212
+K I+ K EKS++ + ++ V ++K D+ ++ + Q KVA + KLE
Sbjct: 661 VPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSKKTTEDQTKVATDSKLE- 719
Query: 213 SNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAV---K 269
A + + + ++D++++ K + +K + + ++ V K
Sbjct: 720 -----------KAADTTKQIETETVVDDKSKKKVLKKKTEKSDSFISQKSETPPVVEPTK 768
Query: 270 ILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKK 329
E + + NK K+ +++ +R+ E+ K +I++ +E E + K+ + K
Sbjct: 769 PAESEAQKIAEVNKAKKQKEVDDNLKREAEVAAK-KIADEKLKIEAEANIKKTAEVEAAK 827
Query: 330 DILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFC---DQL 386
E+ Q K LE EV + KS +KL+ LE+QAQ K D +
Sbjct: 828 KQKEKDEQLK---------------LETEVVSKKSAAEKLE---LEKQAQIKKAAEADAV 869
Query: 387 KKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAF 446
KK +K + +N L A K ++ LE E+ K + EE K E K +
Sbjct: 870 KK--QKELNEKNKLEAAKKSAADKLK-LEEESAAKSKKVSEESV--KFGEEKKTKAGEKT 924
Query: 447 AALENEVSALKSESTK-LKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAAL 505
+E+E ++ K+ TK + ++ K I++K E S++ + + SA SE +
Sbjct: 925 VQVESEPTSKKTIDTKDVGATEPADETPKKKIIKKKTEKSDSSIS---QKSATDSEKVSK 981
Query: 506 QQKCGAGSREGNGDVE-VLKAGISDTEKEVNT---LKKELVEKEKIVADSERKTAVDERK 561
Q++ ++ + + V +A S +KE + L E+ K K AD + K E+
Sbjct: 982 QKEQDEPTKPAVSETQMVTEADKSKKQKETDEKLKLDAEIAAKTKQEADEKSKLDAQEKI 1041
Query: 562 KAAAE---ARKLLE-----------AAKKIAPEKAVIPEPANC--CSKCDELKKKCEKVA 605
K +E ARK E A KK + +K + E A ++ + KK+ EK
Sbjct: 1042 KKVSEDDAARKEKELNDKLKLESEIATKKASADKLKLEEQAQAKKAAEVEAAKKQKEKDE 1101
Query: 606 VGRNALRQAVKILEKGIENLESENK-KLKKENEVSALKSEISALQQ-KCGAGAREGNGDV 663
+ A K + E LE E + ++KK A+K + ++ K A + G +
Sbjct: 1102 QLKLDTEAASK--KAAAEKLELEKQAQIKKAAGADAVKKQKELDEKNKLEANKKSAAGKL 1159
Query: 664 EVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLL-EAPKK--I 720
++ + + +K+ V K + + A+ + K DE+ +E+++ + E PKK +
Sbjct: 1160 KIEEESAAKSKQTVEEQAKLDAQTKAKTAEKQTKLEKDEKSTKESESKETVDEKPKKKVL 1219
Query: 721 AAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEA--EKKKLLVE----- 773
+ EK + + + K V E E K +A ++ + EK+KL E
Sbjct: 1220 KKKTEKSDSSISQKS-ETSKTVVESAGPSESETQKVADAARKQKETDEKQKLEAEITAKK 1278
Query: 774 ------KINAESKIKKAQERSESELDKKTADMEKQQAE-EQKKLAEDKLLL 817
K+ AESK+KKA E ++ K+ + K E KK A +KL L
Sbjct: 1279 SADEKSKLEAESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLEL 1329
Score = 77.0 bits (188), Expect = 2e-12
Identities = 169/816 (20%), Positives = 318/816 (38%), Gaps = 105/816 (12%)
Query: 32 RNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLE--ISNTFAALENEVS 89
R L++ +++E ++ + KK KK + +R+ +L I F + ++
Sbjct: 185 RRRLQRGRRVMEASSDSELDDAKKRKKRRIKRVVERRNPNAPRLTQLIPPRFDKILSDHD 244
Query: 90 ALISENKKLKQDILEEQA-------QGKICDQLKKCEKVVEGRNALRQAVKILEKRIENL 142
A+ EN + + L E GK+ D V + +R+ IL
Sbjct: 245 AIEGENVVMMVETLGEPEPQVRFYRDGKLIDDGSGDRMEVRHEDEMRKHWLIL------- 297
Query: 143 ESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQR 202
K + KD + E A + I + G+ A ++V SE + ++E
Sbjct: 298 ----KDICKDEEAEYACQAINVAGE-------AWCFSDVVVHMSEESRDDDKSVDEVDDS 346
Query: 203 KVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRN 262
V E K + ++ S K++ K +K+ E Q + ++K +V + ++
Sbjct: 347 TVLEEKKDD--------GDDKSKPKTKKKIIKKKETPESEQVTAAEPEQQKISEV-DVQS 397
Query: 263 ALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKS 322
V +K ++ K KKD + + + E E E + N+ ++ KS
Sbjct: 398 VAETEVGAKKKPDAEKPTDLSKAKKDSKSKKSD---EPEASTEEKSTTEKPTNDKTSKKS 454
Query: 323 ENKKL---KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQD----ILE 375
KK KK++ + + K +E K + S ++ E S+ ++ KK KQ +
Sbjct: 455 AEKKTVKPKKEVTGKPLEAKKPVEDKKDASQPSSSKE---SSPPTDGKKKKQIPKALFIP 511
Query: 376 EQAQGKFCDQLKKKCEK----VVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQ 431
++ +F D E + GR A L + + S + +K E A+
Sbjct: 512 DEISSRFGDPSTMHSETNITTTIRGREGSADAKTPLVEPL----SASVSMKVFTLVESAK 567
Query: 432 RKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIE-EKLEISNAFAA 490
K E K + ++ ++ K ++ E+ + IE +K E+ + +
Sbjct: 568 EKAEFSFKRRSETPDDKSRKKEGLPPAKKSEKKDEVTAEKQSTEALIESKKKEVDESKIS 627
Query: 491 LENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVAD 550
+ KSE+ + +K A E DV + I + K+ T+KK+ + + ++
Sbjct: 628 EQQPSDKNKSEVVGVPEK--AAGPETKKDV----SEIEEVPKK-KTIKKKTEKSDSSISQ 680
Query: 551 SER--KTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGR 608
K A D++ K+ + + +KK ++ + + D K+ + V
Sbjct: 681 KSNVLKPADDDKSKSD----DVTDKSKKTTEDQTKVATDSKLEKAADTTKQIETETVVDD 736
Query: 609 NALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKA 668
+ ++ +K KK +K + + KSE + + E EV KA
Sbjct: 737 KSKKKVLK-------------KKTEKSDSFISQKSETPPVVEPTKPAESEAQKIAEVNKA 783
Query: 669 GISDTKKEVN-RLKKEHVEEERIVADSERKTAVDERKNAAAE---ARKLLEAPKKIAAEV 724
+KEV+ LK+E + +AD + K + AE A+K E +++ E
Sbjct: 784 ---KKQKEVDDNLKREAEVAAKKIADEKLKIEAEANIKKTAEVEAAKKQKEKDEQLKLET 840
Query: 725 EKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKA 784
E K ++ LEKQ +K A + K KE EK KL K +A K+K
Sbjct: 841 EVVSKKSAAEKLELEKQAQIKKAAEADAVKKQKELN-----EKNKLEAAKKSAADKLK-- 893
Query: 785 QERSESELDKKTADMEKQQAEEQKKLAEDKLLLLGD 820
L++++A K+ +EE K E+K G+
Sbjct: 894 -------LEEESAAKSKKVSEESVKFGEEKKTKAGE 922
Score = 43.1 bits (100), Expect = 0.037
Identities = 81/357 (22%), Positives = 140/357 (38%), Gaps = 63/357 (17%)
Query: 521 EVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKK---- 576
+++K + ++V + E + ++ S +T V +KK AE L AKK
Sbjct: 367 KIIKKKETPESEQVTAAEPEQQKISEVDVQSVAETEVGAKKKPDAEKPTDLSKAKKDSKS 426
Query: 577 --------IAPEKAVIPEPAN--CCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLE 626
EK+ +P N K E K K V L + +K +
Sbjct: 427 KKSDEPEASTEEKSTTEKPTNDKTSKKSAEKKTVKPKKEVTGKPLEAKKPVEDKKDASQP 486
Query: 627 SENK--------KLKKE--------NEVSALKSEISALQQKCG----AGAREGNGD---- 662
S +K K KK+ +E+S+ + S + + REG+ D
Sbjct: 487 SSSKESSPPTDGKKKKQIPKALFIPDEISSRFGDPSTMHSETNITTTIRGREGSADAKTP 546
Query: 663 -VEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDE-RKNAAAEARKLLEAPKKI 720
VE L A +S +V L + E+ +T D+ RK K E ++
Sbjct: 547 LVEPLSASVS---MKVFTLVESAKEKAEFSFKRRSETPDDKSRKKEGLPPAKKSEKKDEV 603
Query: 721 AAEVEKQIAKVELRQVHLEKQVNERKM-------KLAFELSKTKEATKRFEAEKKKLLVE 773
AE + A +E + +K+V+E K+ K E+ E E +K +E
Sbjct: 604 TAEKQSTEALIESK----KKEVDESKISEQQPSDKNKSEVVGVPEKAAGPETKKDVSEIE 659
Query: 774 KINAESKIKKAQERSESELDKKT-----ADMEKQQAEE----QKKLAEDKLLLLGDS 821
++ + IKK E+S+S + +K+ AD +K ++++ KK ED+ + DS
Sbjct: 660 EVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSKKTTEDQTKVATDS 716
Score = 40.4 bits (93), Expect = 0.24
Identities = 95/408 (23%), Positives = 169/408 (41%), Gaps = 85/408 (20%)
Query: 337 QRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEG 396
++KV LEI+N ++ K K L E G++ Q+ V
Sbjct: 2767 RKKVGDSDWLEIAN-------------TDRNKFKDRSLTES--GEYVYQVTATGIHAVSS 2811
Query: 397 RNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKI--EIEGKLEISNAFAALENEVS 454
+ VKIL G E S+ +K K D + ++++K EI + ++ + A+ E+
Sbjct: 2812 PSEETNPVKILVPGSEMPASKTEK-KTDAAKSESEQKSAEEIVAEKQVDQSQAS-ESTTE 2869
Query: 455 ALKSESTK--LKKDILEEQAQIKVA-IEEKLEISNAFAALENEVSALKSEIAALQQKCGA 511
A++ + TK +KK + E + + + ++EKL+ A +++E
Sbjct: 2870 AVEEKKTKKVVKKKVAENKGEETLQEVKEKLKKGKAVEKVQDE----------------- 2912
Query: 512 GSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLL 571
SR G+ L+A SD E T +K + ++ +SE+ E+K +A+ L
Sbjct: 2913 -SRRGS-----LQAS-SDNESVTTTSEKR--SEAELEKNSEKSA---EKKSTSAD----L 2956
Query: 572 EAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKK 631
EAA K EK+ + ++ KK +KVA +KG+ + +
Sbjct: 2957 EAADKAETEKSETGKETT-----EKKKKVVKKVA-------------KKGLVKADKSKIE 2998
Query: 632 LK--KENEVSALKSEIS-ALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEE 688
L KE E+SA +E +++ K A + + V G+S K + V
Sbjct: 2999 LTAGKEGEISAQVAETGVSVEWKKDGKALDASYTV-TSTGGVSTVKIPI-----VDVNTS 3052
Query: 689 RIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQV 736
+ + + DE + + A KL E PK E E+ I +V++ V
Sbjct: 3053 GVFTCKVKSSEGDEEEVSIAVTVKLPEVPK---VEAEQSIVEVKVGDV 3097
Score = 37.0 bits (84), Expect = 2.6
Identities = 43/205 (20%), Positives = 88/205 (41%), Gaps = 14/205 (6%)
Query: 622 IENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAG----ISDTKKEV 677
I N + K + E +++A + E V++L G S T+K+
Sbjct: 2778 IANTDRNKFKDRSLTESGEYVYQVTATGIHAVSSPSEETNPVKILVPGSEMPASKTEKKT 2837
Query: 678 NRLKKEHVEE--ERIVADSE-RKTAVDERKNAAAEARKLLEAPKKIAAEVEK----QIAK 730
+ K E ++ E IVA+ + ++ E A E +K + KK AE + Q K
Sbjct: 2838 DAAKSESEQKSAEEIVAEKQVDQSQASESTTEAVEEKKTKKVVKKKVAENKGEETLQEVK 2897
Query: 731 VELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSES 790
+L++ ++V + + + + S E+ ++ + +EK + +S KK+
Sbjct: 2898 EKLKKGKAVEKVQDESRRGSLQASSDNESVTTTSEKRSEAELEKNSEKSAEKKSTSADLE 2957
Query: 791 ELDK---KTADMEKQQAEEQKKLAE 812
DK + ++ K+ E++KK+ +
Sbjct: 2958 AADKAETEKSETGKETTEKKKKVVK 2982
Score = 36.2 bits (82), Expect = 4.5
Identities = 63/280 (22%), Positives = 109/280 (38%), Gaps = 76/280 (27%)
Query: 527 ISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPE 586
+S +E N +K +V SE + E+K AA++ ++A++I EK V
Sbjct: 2809 VSSPSEETNPVKI-------LVPGSEMPASKTEKKTDAAKSESEQKSAEEIVAEKQVDQS 2861
Query: 587 PANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEIS 646
A+ + +KK +KV + A KG E L+ +KLKK V ++ E
Sbjct: 2862 QASESTTEAVEEKKTKKVVKKKVAEN-------KGEETLQEVKEKLKKGKAVEKVQDE-- 2912
Query: 647 ALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNA 706
+R G+ L+A + E + SE+++ + KN+
Sbjct: 2913 ---------SRRGS-----LQASS---------------DNESVTTTSEKRSEAELEKNS 2943
Query: 707 AAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAE 766
A K K +A++E A + K T + E
Sbjct: 2944 EKSAEK-----KSTSADLEA-----------------------ADKAETEKSETGKETTE 2975
Query: 767 KKKLLVEKINAESKIKKAQERSESELDK-KTADMEKQQAE 805
KKK +V+K+ + +K ++S+ EL K ++ Q AE
Sbjct: 2976 KKKKVVKKVAKKGLVK--ADKSKIELTAGKEGEISAQVAE 3013
>gb|AAN61518.1| 2MDa_2 protein [Caenorhabditis elegans]
Length = 18519
Score = 149 bits (377), Expect = 3e-34
Identities = 215/841 (25%), Positives = 376/841 (44%), Gaps = 126/841 (14%)
Query: 4 EKAVIPEPANCCSKCEELKKKC---EQVVVGRNALRQAVKILEKGIENLESENKKLKKDI 60
EKA PE S+ EE+ KK ++ +++ Q +L+ ++ + K
Sbjct: 12846 EKAAGPETKKDVSEIEEVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSK 12905
Query: 61 QEEQAQRKVAIEGKLE-ISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE 119
+ + Q KVA + KLE ++T +E E ++ + K K + + Q +
Sbjct: 12906 KTTEDQTKVATDSKLEKAADTTKQIETET--VVDDKSKKKVLKKKTEKSDSFISQKSETP 12963
Query: 120 KVVEG-RNALRQAVKILE-------KRIE-NLESENKKLKKDIQEEQAQRKIEIEGKLEK 170
VVE + A +A KI E K ++ NL+ E + K I +E+ KIE E ++K
Sbjct: 12964 PVVEPTKPAESEAQKIAEVNKAKKQKEVDDNLKREAEVAAKKIADEKL--KIEAEANIKK 13021
Query: 171 SNAFAALENEVSALKSENKKLKKDILEEQ-AQRKVAMEGKLEISNAFAALENEVSALKSE 229
+ A + + K E KL+ +++ ++ A K+ +E + +I A E A+K +
Sbjct: 13022 TAEVEAAKKQKE--KDEQLKLETEVVSKKSAAEKLELEKQAQIKKAA-----EADAVKKQ 13074
Query: 230 NKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDI 289
K+L + E A+ D+LK + E + + ++VK E E + K +K +
Sbjct: 13075 -KELNEKNKLEAAKKSAADKLKLEEESAAKSKKVSEESVKFGE------EKKTKAGEKTV 13127
Query: 290 Q-EEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEI 348
Q E K I+ K +V A + ++ KK I++++ ++ + I
Sbjct: 13128 QVESEPTSKKTIDTK------------DVGATEPADETPKKKIIKKKTEKSDS-----SI 13170
Query: 349 SNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILE 408
S A +VS K +++ K + E Q + D+ KK+ E + + A K +
Sbjct: 13171 SQKSATDSEKVSKQKEQDEPTKPAVSETQMVTE-ADKSKKQKETDEKLKLDAEIAAKTKQ 13229
Query: 409 KGIENLESE-NKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDI 467
+ E + + +K+KK +++ A+++ E+ KL+ LE+E++ K+ + KLK
Sbjct: 13230 EADEKSKLDAQEKIKKVSEDDAARKEKELNDKLK-------LESEIATKKASADKLK--- 13279
Query: 468 LEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGI 527
LEEQAQ K A E + A + + LK + A +K A E ++ KA
Sbjct: 13280 LEEQAQAKKAAEVE-----AAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAG 13334
Query: 528 SDTEKEVNTLKKELVEKEKIVADSERKTAVD----ERKKAAAEARKLLEAAKKIAPEKAV 583
+D K+ +KEL EK K+ A+ +K+A E + AA + + E AK A KA
Sbjct: 13335 ADAVKK----QKELDEKNKLEAN--KKSAAGKLKIEEESAAKSKQTVEEQAKLDAQTKAK 13388
Query: 584 IPEPANCCSKCDELKKKCE-KVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALK 642
E K ++ K+ E K V ++ +K KK +K + + K
Sbjct: 13389 TAEKQTKLEKDEKSTKESESKETVDEKPKKKVLK-------------KKTEKSDSSISQK 13435
Query: 643 SEISALQQKCGAGAREGNGDVEVLKAGISDTKK--EVNRLKKEHVEEERIVADSERKTAV 700
SE S + AG E S+T+K + R +KE E++++ A+ K +
Sbjct: 13436 SETSKTVVE-SAGPSE------------SETQKVADAARKQKETDEKQKLEAEITAKKSA 13482
Query: 701 DERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEAT 760
DE+ AE++ K+ A+VE + EK + ++KL E + K A
Sbjct: 13483 DEKSKLEAESKL-------------KKAAEVEAAKKQKEK---DEQLKLDTEAASKKAAA 13526
Query: 761 KRFEAEKKKLL--VEKINAESKIKKAQE--RSESELDKKTADMEKQQAEEQKKLAEDKLL 816
++ E EK+ + +++A K K+ +E R ESE K AD EK + EEQKK A + L
Sbjct: 13527 EKLELEKQSHIKKAAEVDAVKKQKELEEKQRLESEAATKKADAEKLKLEEQKKKAAEIAL 13586
Query: 817 L 817
+
Sbjct: 13587 I 13587
Score = 140 bits (354), Expect = 1e-31
Identities = 206/817 (25%), Positives = 376/817 (45%), Gaps = 93/817 (11%)
Query: 37 QAVKILEKGIENLESENK-KLKKDI---QEEQAQRKVAIEGKLEISNTFAALENEVSALI 92
Q V ++K + E++ K KL+ +I + + + K+ E KL+ + A + +
Sbjct: 9368 QNVAAVDKEKKQKETDEKQKLEAEIAGKKSTEQKSKLEAEAKLKRAAEEDAAKKQKEKTE 9427
Query: 93 SENKKLKQDILEEQAQGKI-----CDQLKKCEKVVEGRNALRQAVKILEKRIENLESENK 147
+ +KK + LE + Q +I D +KK ++ E +N L K+ ++++ LE ++
Sbjct: 9428 AASKKAAAEKLELEKQAQINKAAEADAVKKQNELDE-QNKLEATKKLAAEKLK-LEEQSA 9485
Query: 148 KLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAME 207
K EEQA K++ + K + + LE + KS + +EE+ ++KV ++
Sbjct: 9486 AKSKQAAEEQA--KLDAQTKAKAAEKQTGLEKDE---KSNKDSGSNETVEEKPKKKV-LK 9539
Query: 208 GKLEISNAFAALENEVSALKSEN----KKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNA 263
K E S++ + +++ S +E+ + Q + D ++ K D+ K+K E + + +
Sbjct: 9540 KKTEKSDSSISQKSDTSKTVAESAGSSESETQKVADATSKQKETDK-KQKLEAEITAKKS 9598
Query: 264 LRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSE 323
+ K LE+E+K +K E+ A+++ E E KL+ LE +V++ K+
Sbjct: 9599 ADEKSK--------LETESKLIKA--AEDAAKKQKEKEDKLK-------LEADVASKKAA 9641
Query: 324 NKKLKKDILEEQAQRKVAMEGKLEISNAFAA----LENEVSALKSENKKLKQDILEEQAQ 379
+KL+ LE+QAQ K A E A LE+E + K+ +KLK LEEQAQ
Sbjct: 9642 AEKLE---LEKQAQIKKAAEADAVKKQKELAEKQKLESEAATKKAAAEKLK---LEEQAQ 9695
Query: 380 -GKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEG 438
K + K +K ++ +N L K E L+ E + K Q + Q K++ +
Sbjct: 9696 INKAAEADAVKKQKELDEKNKLEANKK---SAAEKLKLEEESAAKSKQTVEEQAKLDAQT 9752
Query: 439 KLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSAL 498
K + + LE + + K +K + ++E+ + KV +++K E S++ + ++ S
Sbjct: 9753 KEKTAEKQTGLEKDDKSTKDSESK---ETVDEKPKKKV-LKKKTEKSDSSISQKSVTSKT 9808
Query: 499 KSEIAALQ----QKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERK 554
E QK +R+ E K E E+ T KK EK K+ A+S+ K
Sbjct: 9809 VVESGGPSESETQKVADAARKQKETDEKQKL-----EAEI-TAKKSADEKSKLEAESKLK 9862
Query: 555 TAV-----------DERKKAAAEARKLLEAAKKIAPEK-AVIPEPA--NCCSKCDEL--K 598
A DE+ K EA AA+K+ EK A I + A + K EL K
Sbjct: 9863 KAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAEADAVKKEKELAEK 9922
Query: 599 KKCEKVAVGRNALRQAVKILEKGIENLES-------ENKKLKKENEVSALKSEISALQQK 651
+K E A + A + +K+ E+ ++ E+ E +KL +E + ++ SA +QK
Sbjct: 9923 QKLESEAATKKAAAEKLKLEEQKKKDAETASIEKQKEQEKLAQEQSKLEVDAKKSAEKQK 9982
Query: 652 CGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEAR 711
+ + + ++ KK+V + K E + KT + + +E +
Sbjct: 9983 LESETKSKKTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSDTAKTVAESAGQSDSETQ 10042
Query: 712 KLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLL 771
K+ EA K A + ++ K +L K+ E+K KL E +KTK+ + A+K+K
Sbjct: 10043 KVSEADK--AHKQKESDEKQKLESEIAAKKSAEQKSKLETE-AKTKKVIEDESAKKQKEQ 10099
Query: 772 VEKINAESKIKKAQERSESELDKKTADMEKQQAEEQK 808
+K + KK +++ E + + A +K +E+QK
Sbjct: 10100 EDKKKGDDSAKKQKDQKEKQKLESEATSKKPTSEKQK 10136
Score = 140 bits (353), Expect = 2e-31
Identities = 212/849 (24%), Positives = 362/849 (41%), Gaps = 114/849 (13%)
Query: 9 PEPANCCSKCEELKKKCEQVVVGRNALRQAVKILEKG-IENLESENKKLKKDIQE----- 62
P+P +V + + +A K+ EK LES++K + +E
Sbjct: 9267 PQPGGKSDSSISSTSDASEVKQVQQSESEAQKVTEKPETAKLESKSKMTEDTTKESDNKE 9326
Query: 63 --EQAQRKVAIEGKLEISNTFAALENEVSALIS----ENKKLKQDILEEQAQGKICDQLK 116
++ +K ++ K E S++ + +E SA+ S E++ ++++ + K D+ +
Sbjct: 9327 TVDEKPKKKVLKKKTEKSDSTISETSETSAVESAGPSESETQNVAAVDKEKKQKETDEKQ 9386
Query: 117 KCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAA 176
K E + G+ + Q K LE+E KLK+ +E+ A+++ E K A
Sbjct: 9387 KLEAEIAGKKSTEQKSK--------LEAE-AKLKRAAEEDAAKKQKEKTEAASKKAAAEK 9437
Query: 177 LENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALE---NEVSALKSENKKL 233
LE E A NK + D +++Q ++ + KLE + AA + E SA KS+
Sbjct: 9438 LELEKQA--QINKAAEADAVKKQ--NELDEQNKLEATKKLAAEKLKLEEQSAAKSKQAAE 9493
Query: 234 KQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEH 293
+Q LD Q + K ++ + G+E E NK + E
Sbjct: 9494 EQAKLDAQTKAKAAEK----------------------QTGLEKDEKSNKDSGSNETVEE 9531
Query: 294 AQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFA 353
+K ++ K E S++ + +++ S +E+ E + Q+ K + ++
Sbjct: 9532 KPKKKVLKKKTEKSDSSISQKSDTSKTVAESAGSS----ESETQKVADATSKQKETDKKQ 9587
Query: 354 ALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIEN 413
LE E++A KS ++K K + E + D KK+ EK E + L V + E
Sbjct: 9588 KLEAEITAKKSADEKSKLET-ESKLIKAAEDAAKKQKEK--EDKLKLEADVASKKAAAEK 9644
Query: 414 LESENK-KLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQA 472
LE E + ++KK + + +++ E+ K + LE+E + K+ + KLK LEEQA
Sbjct: 9645 LELEKQAQIKKAAEADAVKKQKELAEKQK-------LESEAATKKAAAEKLK---LEEQA 9694
Query: 473 QIKVAIEEKLEISNAFAALENEVSALKSEIAA---LQQKCGAGSREGNGDVEVLKAGISD 529
QI A E +N++ A K A L+++ A S++ + L A +
Sbjct: 9695 QINKAAEADAVKKQKELDEKNKLEANKKSAAEKLKLEEESAAKSKQTVEEQAKLDAQTKE 9754
Query: 530 TEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEA----AKKIAPEKAVI- 584
E T L + +K DSE K VDE+ K +K ++ ++K K V+
Sbjct: 9755 KTAEKQT---GLEKDDKSTKDSESKETVDEKPKKKVLKKKTEKSDSSISQKSVTSKTVVE 9811
Query: 585 ---PEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSA- 640
P + D +K+ E + K LE+E+K LKK EV A
Sbjct: 9812 SGGPSESETQKVADAARKQKETDEKQKLEAEITAKKSADEKSKLEAESK-LKKAAEVEAA 9870
Query: 641 ---------LKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIV 691
LK + A +K A E ++ KA +D K+ +KE E++++
Sbjct: 9871 KKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAEADAVKK----EKELAEKQKL- 9925
Query: 692 ADSERKTAVDERKNAAAEARKLLEAPKKIA--AEVEKQIAKVELRQ------VHLEKQVN 743
+SE T K AAAE KL E KK A A +EKQ + +L Q V +K
Sbjct: 9926 -ESEAAT-----KKAAAEKLKLEEQKKKDAETASIEKQKEQEKLAQEQSKLEVDAKKSAE 9979
Query: 744 ERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQ 803
++K++ + KT+EA K EK K V K E ++S++ K A+ Q
Sbjct: 9980 KQKLESETKSKKTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSDTA--KTVAESAGQS 10037
Query: 804 AEEQKKLAE 812
E +K++E
Sbjct: 10038 DSETQKVSE 10046
Score = 139 bits (351), Expect = 3e-31
Identities = 207/836 (24%), Positives = 360/836 (42%), Gaps = 117/836 (13%)
Query: 40 KILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLK 99
KI++K E +S + + + ++ Q K + E + T ++++EV K K
Sbjct: 9202 KIMKKKTEKADSSISETSETLTKDLTQTKQS-EPEPAKRTTETSVQDEVKRKTETTSKSK 9260
Query: 100 QDILEEQAQGKICDQ----LKKCEKVVEGRNALRQAVKILEK-RIENLESENKKLK---- 150
Q E G D +V + + + +A K+ EK LES++K +
Sbjct: 9261 QTTEEHPQPGGKSDSSISSTSDASEVKQVQQSESEAQKVTEKPETAKLESKSKMTEDTTK 9320
Query: 151 ----KDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAM 206
K+ +E+ ++K+ ++ K EKS++ + +E SA++S E Q V
Sbjct: 9321 ESDNKETVDEKPKKKV-LKKKTEKSDSTISETSETSAVESAGPSES----ETQNVAAVDK 9375
Query: 207 EGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKV-VEGRNALR 265
E K + ++ LE E++ KS +K K + + + D KK+ EK + A
Sbjct: 9376 EKKQKETDEKQKLEAEIAGKKSTEQKSKLEAEAKLKRAAEEDAAKKQKEKTEAASKKAAA 9435
Query: 266 QAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENK 325
+ +++ ++ N +E +KK Q +++ + KLE + AA E L+ ++
Sbjct: 9436 EKLELEKQAQINKAAEADAVKK-------QNELDEQNKLEATKKLAA---EKLKLEEQSA 9485
Query: 326 KLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQ 385
K EEQA K+ + K + + LE + KS + +EE+ + K
Sbjct: 9486 AKSKQAAEEQA--KLDAQTKAKAAEKQTGLEKDE---KSNKDSGSNETVEEKPKKKV--- 9537
Query: 386 LKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNA 445
LKKK EK + K + + + ESE +K+ +++ K +
Sbjct: 9538 LKKKTEKSDSSISQKSDTSKTVAESAGSSESETQKVADATSKQKETDKKQ---------- 9587
Query: 446 FAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAAL 505
LE E++A KS K K LE ++++ A E+ A + + LK E
Sbjct: 9588 --KLEAEITAKKSADEKSK---LETESKLIKAAED------AAKKQKEKEDKLKLEADVA 9636
Query: 506 QQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKA-- 563
+K A E ++ KA +D K+ +KEL EK+K+ +++ K A E+ K
Sbjct: 9637 SKKAAAEKLELEKQAQIKKAAEADAVKK----QKELAEKQKLESEAATKKAAAEKLKLEE 9692
Query: 564 ------AAEA-----------RKLLEAAKKIAPEKAVIPEPANCCSK--CDELKK----K 600
AAEA + LEA KK A EK + E + SK +E K
Sbjct: 9693 QAQINKAAEADAVKKQKELDEKNKLEANKKSAAEKLKLEEESAAKSKQTVEEQAKLDAQT 9752
Query: 601 CEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAR--E 658
EK A + L + K K E+ E+ ++K KK+ + S++ QK E
Sbjct: 9753 KEKTAEKQTGLEKDDKST-KDSESKETVDEKPKKKVLKKKTEKSDSSISQKSVTSKTVVE 9811
Query: 659 GNGDVEVLKAGISDTKK--EVNRLKKEHVEEERIVADSERKTAVDERKNAAAE------- 709
G E S+T+K + R +KE E++++ A+ K + DE+ AE
Sbjct: 9812 SGGPSE------SETQKVADAARKQKETDEKQKLEAEITAKKSADEKSKLEAESKLKKAA 9865
Query: 710 ----ARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEA 765
A+K E +++ + E K ++ LEKQ +K A + K KE A
Sbjct: 9866 EVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAEADAVKKEKEL-----A 9920
Query: 766 EKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAEDKLLLLGDS 821
EK+KL E ++ +K + + + D +TA +EKQ +EQ+KLA+++ L D+
Sbjct: 9921 EKQKLESEAATKKAAAEKLKLEEQKKKDAETASIEKQ--KEQEKLAQEQSKLEVDA 9974
Score = 127 bits (319), Expect = 1e-27
Identities = 211/867 (24%), Positives = 374/867 (42%), Gaps = 135/867 (15%)
Query: 22 KKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTF 81
K+K E + G+ + Q K+ + +E KK ++ +A K A KLE+
Sbjct: 9385 KQKLEAEIAGKKSTEQKSKLEAEAKLKRAAEEDAAKKQKEKTEAASKKAAAEKLELEK-- 9442
Query: 82 AALENEVSALISENKKLKQDILEEQ----AQGKICDQLKKCEK--VVEGRNALRQAVKI- 134
+ +++ + KQ+ L+EQ A K+ + K E+ + + A + K+
Sbjct: 9443 ---QAQINKAAEADAVKKQNELDEQNKLEATKKLAAEKLKLEEQSAAKSKQAAEEQAKLD 9499
Query: 135 -------LEKR--IENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALK 185
EK+ +E E NK + E+ +K ++ K EKS++ + +++ S
Sbjct: 9500 AQTKAKAAEKQTGLEKDEKSNKDSGSNETVEEKPKKKVLKKKTEKSDSSISQKSDTSKTV 9559
Query: 186 SENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGK 245
+E+ E + Q+ K + ++ LE E++A KS ++K K + + +
Sbjct: 9560 AESAGSS----ESETQKVADATSKQKETDKKQKLEAEITAKKSADEKSKLETESKLIKAA 9615
Query: 246 FCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENK-KLKKDIQEEHAQRKVEIEGKL 304
D KK+ EK E + L V + E LE E + ++KK + + +++ E+ K
Sbjct: 9616 E-DAAKKQKEK--EDKLKLEADVASKKAAAEKLELEKQAQIKKAAEADAVKKQKELAEKQ 9672
Query: 305 EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEG-------------KLEISNA 351
+ LE+E + K+ +KLK LEEQAQ A E KLE +
Sbjct: 9673 K-------LESEAATKKAAAEKLK---LEEQAQINKAAEADAVKKQKELDEKNKLEANKK 9722
Query: 352 FAALE---NEVSALKSENKKLKQDILEEQAQGKFCDQ---LKK--KCEKVVEGRNAL--R 401
AA + E SA KS+ +Q L+ Q + K ++ L+K K K E + + +
Sbjct: 9723 SAAEKLKLEEESAAKSKQTVEEQAKLDAQTKEKTAEKQTGLEKDDKSTKDSESKETVDEK 9782
Query: 402 QAVKILEKGIENLES---ENKKLKKDI------QEEQAQRKIEIEGKLEISNAFAALENE 452
K+L+K E +S + K + E + Q+ + K + ++ LE E
Sbjct: 9783 PKKKVLKKKTEKSDSSISQKSVTSKTVVESGGPSESETQKVADAARKQKETDEKQKLEAE 9842
Query: 453 VSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAG 512
++A KS K K LE ++++K A E + A + + LK + A +K A
Sbjct: 9843 ITAKKSADEKSK---LEAESKLKKAAEVE-----AAKKQKEKDEQLKLDTEAASKKAAAE 9894
Query: 513 SREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLE 572
E ++ KA +D K+ +KEL EK+K+ +SE T KKAAAE KL E
Sbjct: 9895 KLELEKQAQIKKAAEADAVKK----EKELAEKQKL--ESEAAT-----KKAAAEKLKLEE 9943
Query: 573 AAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALR-QAVKILEKGIENLESENKK 631
KK A ++ E +K+ EK+A ++ L A K EK + LESE K
Sbjct: 9944 QKKKDAETASI------------EKQKEQEKLAQEQSKLEVDAKKSAEK--QKLESETKS 9989
Query: 632 LKKEN------------EVSALKSEIS--ALQQKCGAGAR----EGNGDVEVLKAGISDT 673
K E +V K+E S ++ QK G D E K +D
Sbjct: 9990 KKTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSDTAKTVAESAGQSDSETQKVSEADK 10049
Query: 674 KKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVEL 733
+ +KE E++++ ++ K + +++ EA+ + A + ++Q K +
Sbjct: 10050 AHK----QKESDEKQKLESEIAAKKSAEQKSKLETEAKTKKVIEDESAKKQKEQEDKKKG 10105
Query: 734 RQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKI------KKAQER 787
+++ + K KL E + K +++ + EK EK +E++ ++ + +
Sbjct: 10106 DDSAKKQKDQKEKQKLESEATSKKPTSEKQKDEKTP--QEKAKSENETVMTTEPQQLEVK 10163
Query: 788 SESELDKKTADMEKQQAEEQKKLAEDK 814
SE + KT +EK+ A +K + K
Sbjct: 10164 SEPKKSDKTETVEKEVASSTEKSDDSK 10190
Score = 127 bits (318), Expect = 2e-27
Identities = 198/795 (24%), Positives = 365/795 (45%), Gaps = 77/795 (9%)
Query: 57 KKDIQEEQAQRKVA---IEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICD 113
+KD+ +A +E + + ++E++ + ++ KK K D +++A K+
Sbjct: 6948 QKDVPVPEANAPTVEPTVEKLAPVESKETSVESKETQADAKLKKEKDDKHKQEADAKL-- 7005
Query: 114 QLKKCEKVVEGRNALRQAVKILEKRIENLESE-NKKLKKDIQEEQAQRKIEIEGKLEKSN 172
Q + +K+ + +A K+ ++ + L+ E + KLKK+ ++ Q E + KL+K N
Sbjct: 7006 QKENDDKLKQEADA-----KLKKENDDKLKQEADAKLKKENDDKLKQ---EADAKLKKEN 7057
Query: 173 AFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKK 232
+ + LK EN D L+++A K+ E ++ E + K + K
Sbjct: 7058 DDKLKQEAAAKLKKEND----DKLKQEADAKLKKENDDKLKQ-----EADAKLQKENDDK 7108
Query: 233 LKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENK-KLKKDIQE 291
LKQ+ D + Q + D+LK++ + ++ N K+ ++ L+ EN KLK QE
Sbjct: 7109 LKQEA-DAKLQKENDDKLKQEADAKLQKEND----DKLKQEADAKLQKENDDKLK---QE 7160
Query: 292 EHAQRKVEIEGKL-EISNAFAALENEVSALKSENKKLKK---DILEEQAQRKVAMEGKLE 347
A+ + E + KL + ++A EN+ + + KLKK D L+++A K+ E +
Sbjct: 7161 ADAKLQKENDDKLKQEADAKLKKENDDKLKQEADAKLKKEKHDKLKQEADAKLQKENDDK 7220
Query: 348 ISN-AFAALENEVS-ALKSEN----KKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALR 401
+ A A L+ E LK E +K K D L+++A K K+K +K+ + +A
Sbjct: 7221 LKQEADAKLQKENDDKLKQEADAKLQKEKDDKLKQEADAKL---KKEKDDKLKQDADAKL 7277
Query: 402 QAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSEST 461
Q K +K + +++ KK K D + +A K++ E ++ E + K +
Sbjct: 7278 QKEKD-DKLKQEADAKLKKEKDDKLKHEADAKLQKEKDDKLKQ-----EADAKLKKEKDD 7331
Query: 462 KLKKDILEEQAQIKVAIEEKLEISNAFAALENEVS-ALKSEIAALQQKCGAGSREGNGDV 520
+LKKD A+++ ++KL+ A A L+ E LK E A QK + D
Sbjct: 7332 RLKKDA---DAKLQKEKDDKLK-QEADAKLKKEKDDKLKHEADAKLQKEKDDKLKQEADA 7387
Query: 521 EVLKAGISDTEKEVNT-LKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAP 579
++ K ++E + L+KE +K K AD++ K D++ K A+A+ E K+
Sbjct: 7388 KLKKEKDDKLKQEADAKLQKEKDDKLKQEADAKLKKEKDDKLKQEADAKLQKEKDDKLKQ 7447
Query: 580 EKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESE-NKKLKKENEV 638
E + E K +K + K+ ++ + L+ E + KLKKE +
Sbjct: 7448 EADAKLKKEKDDKLKQEADAKLQKEKDDKLKQEADAKLKKEKDDKLKQEADAKLKKEKD- 7506
Query: 639 SALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVN-RLKKEHVEEERIVADSERK 697
LK + A QK + D ++ K K E + +LKKE ++ + AD++ K
Sbjct: 7507 DKLKQDADAKLQKEKDDKLKQEADAKLKKEKDDKLKHEADAKLKKEKDDKLKQEADAKLK 7566
Query: 698 TAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVE---LRQVHLEKQVNERKMKLAFELS 754
D++ A+A+ E K+ E + ++ K + +Q K E+ KL E
Sbjct: 7567 KEKDDKLKQDADAKLKKEKDDKLKHEADAKLQKEKDDNFKQEANAKLQKEKDDKLKQEKD 7626
Query: 755 KT--KEATKRFEAEKKKLLVE------KINAESKIKKAQE-----RSESELDKKTADMEK 801
+EA + + EK L + K A++K+KK ++ ++++L K+ D K
Sbjct: 7627 DNFKQEANAKLQKEKDDKLKQEKDDKLKQEADAKLKKEKDDKLKQEADAKLKKEKDDKLK 7686
Query: 802 QQAEEQ-KKLAEDKL 815
Q+A+ + KK +DKL
Sbjct: 7687 QEADAKLKKDKDDKL 7701
Score = 125 bits (313), Expect = 7e-27
Identities = 200/811 (24%), Positives = 360/811 (43%), Gaps = 97/811 (11%)
Query: 50 ESENKKLKKDI-----QEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILE 104
+ ++ KLK+D +E+ + K + KL+ L++E A + KK K D L+
Sbjct: 7503 KEKDDKLKQDADAKLQKEKDDKLKQEADAKLKKEKD-DKLKHEADAKL---KKEKDDKLK 7558
Query: 105 EQAQGKIC----DQLK-----KCEKVVEGRNALRQAVKILEKRIENLESE-NKKLKKDI- 153
++A K+ D+LK K +K + + K+ +++ +N + E N KL+K+
Sbjct: 7559 QEADAKLKKEKDDKLKQDADAKLKKEKDDKLKHEADAKLQKEKDDNFKQEANAKLQKEKD 7618
Query: 154 ----QEEQAQRKIEIEGKLEKSNAFAALENEVSALKSEN----KKLKKDILEEQAQRKVA 205
QE+ K E KL+K + + LK E KK K D L+++A K+
Sbjct: 7619 DKLKQEKDDNFKQEANAKLQKEKDDKLKQEKDDKLKQEADAKLKKEKDDKLKQEADAKLK 7678
Query: 206 MEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALR 265
E ++ E + K ++ KLKQ+ D + + + D+LK++ +
Sbjct: 7679 KEKDDKLKQ-----EADAKLKKDKDDKLKQEA-DAKLKKEKDDKLKQEAD---------- 7722
Query: 266 QAVKILEKGIENLESE-NKKLKKDI-----QEEHAQRKVEIEGKL-EISNAFAALENEVS 318
K+ + + L+ E + KLKKD QE A+ K E + KL + N E +
Sbjct: 7723 --AKLKKDKDDKLKQEADAKLKKDKDDKLKQEADAKLKKEKDDKLKQEKNDKLKQEADAK 7780
Query: 319 ALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSEN----KKLKQDIL 374
K ++ KLK+ E A+ K + KL+ +++ LK E KK K D L
Sbjct: 7781 LKKEKDDKLKQ---EADAKLKKEKDDKLKQETDAKLKKDKDDKLKQEADAKLKKDKDDKL 7837
Query: 375 EEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESE-NKKLKKDIQEEQAQRK 433
+++A K K ++ +G+ + K+ ++ L+ E + KLK QE A+ K
Sbjct: 7838 KQEADAKLKKDKDDKLKQEADGKLKKEKDNKLKQEADGKLKKEKDNKLK---QEADAKLK 7894
Query: 434 IEIEGKLEISNAFAALENEVS-ALKSES-TKLKKDI-----LEEQAQIKVAIEEKLEISN 486
E + KL+ A A L+ E LK E+ KLKKD E A++K ++KL+
Sbjct: 7895 KEKDDKLK-QEADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEADAKLKKEKDDKLKQEA 7953
Query: 487 AFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNT-LKKELVEKE 545
+++ LK E A QK + D ++ K ++E + LKKE +K
Sbjct: 7954 DAKLKKDKDDKLKQEANAKLQKEKDDKLKQEADAKLQKEKDDKLKQEADAKLKKEKDDKL 8013
Query: 546 KIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVA 605
K AD++ + D++ K A+A+ E K+ E + K+K +
Sbjct: 8014 KQEADAKLQKEKDDKLKQEADAKLKKEKDDKLKQE-----------ADAKLQKEKDDNFK 8062
Query: 606 VGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEV 665
NA Q EK + + ++ KLK+E + K + L+Q+ A ++ D
Sbjct: 8063 QEANAKLQK----EKDDKLKQEKDDKLKQEADAKLKKEKDDKLKQEADAKLKKDKDDKLK 8118
Query: 666 LKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVE 725
+A K++ ++LK+E AD++ K D++ A+A+ + K+ E +
Sbjct: 8119 QEADAKLKKEKDDKLKQE--------ADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEAD 8170
Query: 726 KQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQ 785
++ K + ++ E +K K +T K+ + +K K + + K K +
Sbjct: 8171 AKLKKDKDDKLKQEADAKLKKEKDDKLKQETDAKLKKDKDDKLKQEADAKLKKEKDDKLK 8230
Query: 786 ERSESELDKKTADMEKQQAEEQ-KKLAEDKL 815
+ ++++L K+ D KQ+A+ + KK +DKL
Sbjct: 8231 QEADAKLKKEKDDKLKQEADAKLKKEKDDKL 8261
Score = 117 bits (294), Expect = 1e-24
Identities = 186/840 (22%), Positives = 357/840 (42%), Gaps = 92/840 (10%)
Query: 19 EELKKKCEQV---VVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKL 75
EELK QV VV + ++ +E+ L+ ++KK KK E + ++A+E
Sbjct: 9053 EELKLDDVQVNNEVVTEITIEESEVTIEEH-RKLKKKSKKSKKTTDEPELDSEIALEVSS 9111
Query: 76 EISNTFAALENEVSALISENKKLKQDILE------EQAQGKICDQL-KKCEKVVEGRNAL 128
+I+++ LE + I + Q+ L E KI + + +K V A+
Sbjct: 9112 DITSS---LEITTESTIPDTAPESQETLNVEIAVTETTVQKITNPSDESAKKDVNEDTAV 9168
Query: 129 RQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSEN 188
VK +K + KK + E K EI+GK EK E S++ +
Sbjct: 9169 SSIVKKDDKDVN---------KKSLPESGLTTKKEIQGKPEKKIMKKKTEKADSSISETS 9219
Query: 189 KKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCD 248
+ L KD+ + + + E S +++EV K KQ + G D
Sbjct: 9220 ETLTKDLTQTKQSEPEPAKRTTETS-----VQDEVKRKTETTSKSKQTTEEHPQPGGKSD 9274
Query: 249 RL---KKKCEKVVEGRNALRQAVKILEKG-IENLESENKKLK--------KDIQEEHAQR 296
+V + + + +A K+ EK LES++K + K+ +E ++
Sbjct: 9275 SSISSTSDASEVKQVQQSESEAQKVTEKPETAKLESKSKMTEDTTKESDNKETVDEKPKK 9334
Query: 297 KVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALE 356
KV ++ K E S++ + +E SA++S E Q V E K + ++ LE
Sbjct: 9335 KV-LKKKTEKSDSTISETSETSAVESAGPSES----ETQNVAAVDKEKKQKETDEKQKLE 9389
Query: 357 NEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKV-VEGRNALRQAVKILEKGIENLE 415
E++ KS +K K + + + D KK+ EK + A + +++ ++ N
Sbjct: 9390 AEIAGKKSTEQKSKLEAEAKLKRAAEEDAAKKQKEKTEAASKKAAAEKLELEKQAQINKA 9449
Query: 416 SENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALE---NEVSALKSESTKLKKDILEEQA 472
+E +KK Q +++ + KLE + AA + E SA KS+ ++ L+ Q
Sbjct: 9450 AEADAVKK-------QNELDEQNKLEATKKLAAEKLKLEEQSAAKSKQAAEEQAKLDAQT 9502
Query: 473 QIKVAIE----EKLEISNAFAALENEVSALKSEIAALQQKC-----GAGSREGNGDVEVL 523
+ K A + EK E SN + NE K + L++K +
Sbjct: 9503 KAKAAEKQTGLEKDEKSNKDSG-SNETVEEKPKKKVLKKKTEKSDSSISQKSDTSKTVAE 9561
Query: 524 KAGISDTEKE----VNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAP 579
AG S++E + + +KE +K+K+ A+ K + DE+ K E+ KL++AA+ A
Sbjct: 9562 SAGSSESETQKVADATSKQKETDKKQKLEAEITAKKSADEKSKLETES-KLIKAAEDAAK 9620
Query: 580 EKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVS 639
++ K E K K E + A + +++ ++ +E +KK+ E++
Sbjct: 9621 KQ-----------KEKEDKLKLEADVASKKAAAEKLELEKQAQIKKAAEADAVKKQKELA 9669
Query: 640 AL-KSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKT 698
K E A +K A + ++ KA E + +KK+ +E+ ++ +K+
Sbjct: 9670 EKQKLESEAATKKAAAEKLKLEEQAQINKAA------EADAVKKQKELDEKNKLEANKKS 9723
Query: 699 AVDERK---NAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSK 755
A ++ K +AA++++ +E K+ A+ +++ A+ + +K + + K +
Sbjct: 9724 AAEKLKLEEESAAKSKQTVEEQAKLDAQTKEKTAEKQTGLEKDDKSTKDSESKETVDEKP 9783
Query: 756 TKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAEDKL 815
K+ K+ + + +K + ++ SESE K KQ+ ++K+ E ++
Sbjct: 9784 KKKVLKKKTEKSDSSISQKSVTSKTVVESGGPSESETQKVADAARKQKETDEKQKLEAEI 9843
Score = 117 bits (293), Expect = 2e-24
Identities = 196/771 (25%), Positives = 352/771 (45%), Gaps = 90/771 (11%)
Query: 43 EKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDI 102
EK + + + KLKKD ++ Q + KL+ + L+ E A + KK K D
Sbjct: 7800 EKDDKLKQETDAKLKKDKDDKLKQEA---DAKLK-KDKDDKLKQEADAKL---KKDKDDK 7852
Query: 103 LEEQAQGKICDQLKKCEKVVEGRNALRQAV--KILEKRIENLESE-NKKLKKDI-----Q 154
L+++A GK LKK E N L+Q K+ +++ L+ E + KLKK+ Q
Sbjct: 7853 LKQEADGK----LKK-----EKDNKLKQEADGKLKKEKDNKLKQEADAKLKKEKDDKLKQ 7903
Query: 155 EEQAQRKIEIEGKLEKSNAFAALENEVSALKSEN----KKLKKDILEEQAQRKVAMEGKL 210
E A+ K E + KL++ +++ LK E KK K D L+++A K+ +
Sbjct: 7904 EADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEADAKLKKEKDDKLKQEADAKLKKDKDD 7963
Query: 211 EISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVV--EGRNALRQAV 268
++ E K ++ KLKQ+ D + Q + D+LK++ + + E + L+Q
Sbjct: 7964 KLKQ-----EANAKLQKEKDDKLKQEA-DAKLQKEKDDKLKQEADAKLKKEKDDKLKQEA 8017
Query: 269 --KILEKGIENLESE-NKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSEN- 324
K+ ++ + L+ E + KLKK E+ + K E + KL+ + + L+ E
Sbjct: 8018 DAKLQKEKDDKLKQEADAKLKK---EKDDKLKQEADAKLQKEKDDNFKQEANAKLQKEKD 8074
Query: 325 ---KKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDI---LEEQA 378
K+ K D L+++A K+ E ++ E + K ++ KLKQ+ L+++
Sbjct: 8075 DKLKQEKDDKLKQEADAKLKKEKDDKLKQ-----EADAKLKKDKDDKLKQEADAKLKKEK 8129
Query: 379 QGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESE-NKKLKKDI-----QEEQAQR 432
K + K +K + + K+ + + L+ E + KLKKD QE A+
Sbjct: 8130 DDKLKQEADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEADAKLKKDKDDKLKQEADAKL 8189
Query: 433 KIEIEGKLEISNAFAALENEVSALKSES-TKLKK---DILEEQAQIKVAIEEKLEISN-A 487
K E + KL+ +++ LK E+ KLKK D L+++A K+ E+ ++ A
Sbjct: 8190 KKEKDDKLKQETDAKLKKDKDDKLKQEADAKLKKEKDDKLKQEADAKLKKEKDDKLKQEA 8249
Query: 488 FAALENEVS-ALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVN-TLKKELVEKE 545
A L+ E LK E A +K + D ++ K ++E + LKKE K
Sbjct: 8250 DAKLKKEKDDKLKQEADAKLKKDKDDKLKQEADAKLKKDKDDKLKQEADGKLKKEKDNKL 8309
Query: 546 KIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVA 605
K AD + K D + K A+A+ E K+ E + K D+LK++ +
Sbjct: 8310 KQEADGKLKKEKDNKLKQEADAKLKKEKDDKLKQEADAKLKK----DKDDKLKQEAD--- 8362
Query: 606 VGRNALRQAVKILEKGIENLESE-NKKLKKENEVSALKSEISALQQKCGAGAREGNGDVE 664
K+ ++ + L+ E + KLKKE + LK E A +K + D +
Sbjct: 8363 ---------AKLKKEKDDKLKQEADAKLKKEKD-DKLKQEADAKLKKDKDDKLKQEADAK 8412
Query: 665 VLKAGISDTKKEVN-RLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAE 723
+ K K+E + +LKKE ++ + AD++ K D++ A+A+ + K+ E
Sbjct: 8413 LKKDKDDKLKQEADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEADAKLKKDKDDKLKQE 8472
Query: 724 VEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEK 774
+ ++ K + ++ LE Q N+ ++ FE + E T + +++ ++V K
Sbjct: 8473 ADAKLKKEKGDKLKLEDQTNQSRI---FE-ETSIEVTSLLKCKQQAIIVSK 8519
Score = 112 bits (279), Expect = 6e-23
Identities = 185/787 (23%), Positives = 341/787 (42%), Gaps = 103/787 (13%)
Query: 83 ALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENL 142
A ++E ++ K+ + ++E + K D+ K E+ +N + V + EK
Sbjct: 12796 AKKSEKKDEVTAEKQSTEALIESKK--KEVDESKISEQQPSDKNK-SEVVGVPEK----- 12847
Query: 143 ESENKKLKKDIQE-EQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEE--- 198
+ + KKD+ E E+ +K I+ K EKS++ + ++ V ++K D+ ++
Sbjct: 12848 -AAGPETKKDVSEIEEVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSKK 12906
Query: 199 --QAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEK 256
+ Q KVA + KLE A + + + ++D++++ K + +K +
Sbjct: 12907 TTEDQTKVATDSKLE------------KAADTTKQIETETVVDDKSKKKVLKKKTEKSDS 12954
Query: 257 VVEGRNALRQAV---KILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAAL 313
+ ++ V K E + + NK K+ +++ +R+ E+ K +I++ +
Sbjct: 12955 FISQKSETPPVVEPTKPAESEAQKIAEVNKAKKQKEVDDNLKREAEVAAK-KIADEKLKI 13013
Query: 314 ENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDI 373
E E + K+ + K E+ Q K LE EV + KS +KL+
Sbjct: 13014 EAEANIKKTAEVEAAKKQKEKDEQLK---------------LETEVVSKKSAAEKLE--- 13055
Query: 374 LEEQAQGKFC---DQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQA 430
LE+QAQ K D +KK +K + +N L A K ++ LE E+ K + EE
Sbjct: 13056 LEKQAQIKKAAEADAVKK--QKELNEKNKLEAAKKSAADKLK-LEEESAAKSKKVSEESV 13112
Query: 431 QRKIEIEGKLEISNAFAALENEVSALKSESTK-LKKDILEEQAQIKVAIEEKLEISNAFA 489
K E K + +E+E ++ K+ TK + ++ K I++K E S++
Sbjct: 13113 --KFGEEKKTKAGEKTVQVESEPTSKKTIDTKDVGATEPADETPKKKIIKKKTEKSDSSI 13170
Query: 490 ALENEVSALKSEIAALQQKCGAGSREGNGDVE-VLKAGISDTEKEVNT---LKKELVEKE 545
+ + SA SE + Q++ ++ + + V +A S +KE + L E+ K
Sbjct: 13171 S---QKSATDSEKVSKQKEQDEPTKPAVSETQMVTEADKSKKQKETDEKLKLDAEIAAKT 13227
Query: 546 KIVADSERKTAVDERKKAAAE---ARKLLE-----------AAKKIAPEKAVIPEPANC- 590
K AD + K E+ K +E ARK E A KK + +K + E A
Sbjct: 13228 KQEADEKSKLDAQEKIKKVSEDDAARKEKELNDKLKLESEIATKKASADKLKLEEQAQAK 13287
Query: 591 -CSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENK-KLKKENEVSALKSEISAL 648
++ + KK+ EK + A K + E LE E + ++KK A+K +
Sbjct: 13288 KAAEVEAAKKQKEKDEQLKLDTEAASK--KAAAEKLELEKQAQIKKAAGADAVKKQKELD 13345
Query: 649 QQ-KCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAA 707
++ K A + G +++ + + +K+ V K + + A+ + K DE+
Sbjct: 13346 EKNKLEANKKSAAGKLKIEEESAAKSKQTVEEQAKLDAQTKAKTAEKQTKLEKDEKSTKE 13405
Query: 708 AEARKLL-EAPKK--IAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFE 764
+E+++ + E PKK + + EK + + + K V E E K +A ++ +
Sbjct: 13406 SESKETVDEKPKKKVLKKKTEKSDSSISQKS-ETSKTVVESAGPSESETQKVADAARKQK 13464
Query: 765 A--EKKKLLVE-----------KINAESKIKKAQERSESELDKKTADMEKQQAE-EQKKL 810
EK+KL E K+ AESK+KKA E ++ K+ + K E KK
Sbjct: 13465 ETDEKQKLEAEITAKKSADEKSKLEAESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKA 13524
Query: 811 AEDKLLL 817
A +KL L
Sbjct: 13525 AAEKLEL 13531
Score = 92.8 bits (229), Expect = 4e-17
Identities = 149/604 (24%), Positives = 285/604 (46%), Gaps = 76/604 (12%)
Query: 12 ANCCSKCEEL--KKKCEQVVVGRNALRQAVKILEKGIEN--LESENKKLKKDIQEE---Q 64
A+ K +EL K+K E + A + +K+ E+ N E++ K +K++ E+ +
Sbjct: 9659 ADAVKKQKELAEKQKLESEAATKKAAAEKLKLEEQAQINKAAEADAVKKQKELDEKNKLE 9718
Query: 65 AQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKI-CDQLKKCEKVVE 123
A +K A E KL++ AA + + E KL E+ A+ + ++ K K E
Sbjct: 9719 ANKKSAAE-KLKLEEESAAKSKQT---VEEQAKLDAQTKEKTAEKQTGLEKDDKSTKDSE 9774
Query: 124 GRNAL--RQAVKILEKRIENLES---ENKKLKKDI------QEEQAQRKIEIEGKLEKSN 172
+ + + K+L+K+ E +S + K + E + Q+ + K ++++
Sbjct: 9775 SKETVDEKPKKKVLKKKTEKSDSSISQKSVTSKTVVESGGPSESETQKVADAARKQKETD 9834
Query: 173 AFAALENEVSALKSENKKLKKDILEEQAQRKVAME----GKLEISNAFAALENEVSALKS 228
LE E++A KS ++K K LE +++ K A E K + + L+ E ++ K+
Sbjct: 9835 EKQKLEAEITAKKSADEKSK---LEAESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKA 9891
Query: 229 ENKKLKQDILDEQAQGKFC---DRLKK--------KCEKVVEGRNALRQAVKILEKGIEN 277
+KL+ L++QAQ K D +KK K E + A + +K+ E+ ++
Sbjct: 9892 AAEKLE---LEKQAQIKKAAEADAVKKEKELAEKQKLESEAATKKAAAEKLKLEEQKKKD 9948
Query: 278 LESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQ 337
E+ + + +K+ QE+ AQ + ++E + S LE+E + K+E + K+ ++E+ +
Sbjct: 9949 AETASIEKQKE-QEKLAQEQSKLEVDAKKSAEKQKLESETKSKKTE--EAPKESVDEKPK 10005
Query: 338 RKVAMEGKLEISNAFAALENEV------SALKSENKKLKQDILEEQAQGKFCDQLKKKCE 391
+KV ++ K E S++ + +++ SA +S+++ K ++ + K D+ K+K E
Sbjct: 10006 KKV-LKKKTEKSDSSISQKSDTAKTVAESAGQSDSETQKVSEADKAHKQKESDE-KQKLE 10063
Query: 392 KVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALEN 451
+ + + Q K LE+E K KK I++E A+++ E E K + ++ ++
Sbjct: 10064 SEIAAKKSAEQKSK--------LETE-AKTKKVIEDESAKKQKEQEDKKKGDDSAKKQKD 10114
Query: 452 EVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGA 511
+ K ES K E+ + + +EK A ENE + + +E L+ K
Sbjct: 10115 QKEKQKLESEATSKKPTSEKQKDEKTPQEK-------AKSENE-TVMTTEPQQLEVKSEP 10166
Query: 512 GSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKK--AAAEARK 569
+ VE K S TEK ++ KE EK+KI+ + T E K ++ E+R
Sbjct: 10167 KKSDKTETVE--KEVASSTEKSDDSKTKEPKEKKKIIKKKKDTTKPQEASKELSSDESRI 10224
Query: 570 LLEA 573
LE+
Sbjct: 10225 DLES 10228
Score = 76.3 bits (186), Expect = 4e-12
Identities = 99/462 (21%), Positives = 199/462 (42%), Gaps = 47/462 (10%)
Query: 396 GRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSA 455
G A + +++ + ES + +++++ + Q E+ ++ I + +E E
Sbjct: 9026 GEGAPSEIIEVNTLDYDQEESFDFAGEEELKLDDVQVNNEVVTEITIEESEVTIE-EHRK 9084
Query: 456 LKSESTKLKKDILEEQAQIKVAIEEKLEISNAFA----------------ALENEVSALK 499
LK +S K KK E + ++A+E +I+++ L E++ +
Sbjct: 9085 LKKKSKKSKKTTDEPELDSEIALEVSSDITSSLEITTESTIPDTAPESQETLNVEIAVTE 9144
Query: 500 SEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVE-----KEKIVADSERK 554
+ + + +++ + + + + +K+VN KK L E K++I E+K
Sbjct: 9145 TTVQKITNPSDESAKKDVNEDTAVSSIVKKDDKDVN--KKSLPESGLTTKKEIQGKPEKK 9202
Query: 555 TAVDERKKAAAEARKLLEA-AKKIAPEKAVIPEPANCCSKC---DELKKKCEKVAVGRNA 610
+ +KA + + E K + K PEPA ++ DE+K+K E + +
Sbjct: 9203 IMKKKTEKADSSISETSETLTKDLTQTKQSEPEPAKRTTETSVQDEVKRKTETTSKSKQT 9262
Query: 611 LRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGI 670
+ + K ++ S + + +V +SE + +K E +
Sbjct: 9263 TEEHPQPGGKSDSSISSTSDA-SEVKQVQQSESEAQKVTEKPETAKLESKSKMTEDTTKE 9321
Query: 671 SDTKKEVNR------LKKEHVEEERIVADSERKTAVDERKNAAAEARKL--LEAPKKIAA 722
SD K+ V+ LKK+ + + ++++ +AV+ + +E + + ++ KK
Sbjct: 9322 SDNKETVDEKPKKKVLKKKTEKSDSTISETSETSAVESAGPSESETQNVAAVDKEKKQKE 9381
Query: 723 EVEKQIAKVELRQVHLEKQVN----ERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAE 778
EKQ + E+ +Q + E K+K A E K+ ++ EA KK EK+ E
Sbjct: 9382 TDEKQKLEAEIAGKKSTEQKSKLEAEAKLKRAAEEDAAKKQKEKTEAASKKAAAEKLELE 9441
Query: 779 SKIKKAQERSESELD--KKTADMEKQ-QAEEQKKLAEDKLLL 817
K+AQ +E D KK ++++Q + E KKLA +KL L
Sbjct: 9442 ---KQAQINKAAEADAVKKQNELDEQNKLEATKKLAAEKLKL 9480
Score = 75.5 bits (184), Expect = 7e-12
Identities = 169/816 (20%), Positives = 318/816 (38%), Gaps = 109/816 (13%)
Query: 32 RNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLE--ISNTFAALENEVS 89
R L++ +++E ++ + KK KK + +R+ +L I F + ++
Sbjct: 12391 RRRLQRGRRVMEASSDSELDDAKKRKKRRIKRVVERRNPNAPRLTQLIPPRFDKILSDHD 12450
Query: 90 ALISENKKLKQDILEEQA-------QGKICDQLKKCEKVVEGRNALRQAVKILEKRIENL 142
A+ EN + + L E GK+ D V + +R+ IL
Sbjct: 12451 AIEGENVVMMVETLGEPEPQVRFYRDGKLIDDGSGDRMEVRHEDEMRKHWLIL------- 12503
Query: 143 ESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQR 202
K + KD + E A + I + G+ A ++V SE + ++E
Sbjct: 12504 ----KDICKDEEAEYACQAINVAGE-------AWCFSDVVVHMSEESRDDDKSVDEVDDS 12552
Query: 203 KVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRN 262
V E K + ++ S K++ K +K+ E Q + ++K +V + ++
Sbjct: 12553 TVLEEKKDD--------GDDKSKPKTKKKIIKKKETPESEQVTAAEPEQQKISEV-DVQS 12603
Query: 263 ALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKS 322
V +K ++ K KKD + + + E E E + N+ ++ KS
Sbjct: 12604 VAETEVGAKKKPDAEKPTDLSKAKKDSKSKKSD---EPEASTEEKSTTEKPTNDKTSKKS 12660
Query: 323 ENKKL---KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQD----ILE 375
KK KK++ + + K +E K + S ++ E S+ ++ KK KQ +
Sbjct: 12661 AEKKTVKPKKEVTGKPLEAKKPVEDKKDASQPSSSKE---SSPPTDGKKKKQIPKALFIP 12717
Query: 376 EQAQGKFCDQLKKKCEK----VVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQ 431
++ +F D E + GR A L +E L + ++ E A+
Sbjct: 12718 DEISSRFGDPSTMHSETNITTTIRGREGSADAKTPL---VEPLSAS-----VSMKVESAK 12769
Query: 432 RKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIE-EKLEISNAFAA 490
K E K + ++ ++ K ++ E+ + IE +K E+ + +
Sbjct: 12770 EKAEFSFKRRSETPDDKSRKKEGLPPAKKSEKKDEVTAEKQSTEALIESKKKEVDESKIS 12829
Query: 491 LENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVAD 550
+ KSE+ + +K A E DV + I + K+ T+KK+ + + ++
Sbjct: 12830 EQQPSDKNKSEVVGVPEK--AAGPETKKDV----SEIEEVPKK-KTIKKKTEKSDSSISQ 12882
Query: 551 SER--KTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGR 608
K A D++ K+ + + +KK ++ + + D K+ + V
Sbjct: 12883 KSNVLKPADDDKSKSD----DVTDKSKKTTEDQTKVATDSKLEKAADTTKQIETETVVDD 12938
Query: 609 NALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKA 668
+ ++ +K KK +K + + KSE + + E EV KA
Sbjct: 12939 KSKKKVLK-------------KKTEKSDSFISQKSETPPVVEPTKPAESEAQKIAEVNKA 12985
Query: 669 GISDTKKEVN-RLKKEHVEEERIVADSERKTAVDERKNAAAE---ARKLLEAPKKIAAEV 724
+KEV+ LK+E + +AD + K + AE A+K E +++ E
Sbjct: 12986 ---KKQKEVDDNLKREAEVAAKKIADEKLKIEAEANIKKTAEVEAAKKQKEKDEQLKLET 13042
Query: 725 EKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKA 784
E K ++ LEKQ +K A + K KE EK KL K +A K+K
Sbjct: 13043 EVVSKKSAAEKLELEKQAQIKKAAEADAVKKQKELN-----EKNKLEAAKKSAADKLK-- 13095
Query: 785 QERSESELDKKTADMEKQQAEEQKKLAEDKLLLLGD 820
L++++A K+ +EE K E+K G+
Sbjct: 13096 -------LEEESAAKSKKVSEESVKFGEEKKTKAGE 13124
Score = 68.9 bits (167), Expect = 6e-10
Identities = 152/786 (19%), Positives = 315/786 (39%), Gaps = 108/786 (13%)
Query: 93 SENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKD 152
S+ KK ++ L Q K LKK + E A ++ ++ +++ NK +KK
Sbjct: 10740 SKTKKQEKSALSVQEMNK---SLKKKGEKGEAETAASDFIENADQTGMSIQDLNKSMKKK 10796
Query: 153 IQEEQAQRKIEIEGKLEKSNAFAALENEVS-ALKSENKKLKKDILEEQAQRKVAMEGKLE 211
++ +A +I + ++ + +++ S KSEN+ + + L++ + + K+
Sbjct: 10797 VESGEATGQINDASNNKDADELSIQDSQQSLKKKSENESVTGEQLDKSQE---VEDDKMT 10853
Query: 212 ISNAFAALE-----NEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEK--VVEGRNAL 264
I + +++ EVS KSE K K+ DE + + +KKK E V +G++
Sbjct: 10854 IQSLKKSIKKKPESREVSGGKSEKSKEKES--DEMSIQQLNKSVKKKPENEAVTQGKSGK 10911
Query: 265 RQ-------AVKILEK------GIENLE-------SENKKLKKDIQEEHAQRKVEIEGKL 304
Q +++ L K G++ +E S+ +L + + ++E
Sbjct: 10912 SQEQESDKMSIQALNKSMKKKDGVDGVEGNINIGRSDGDQLSVNDIDAELSTSEQVENAS 10971
Query: 305 EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKS 364
+ A A + + +L++ K++ K + +A+ K+ G+ + + L++ LK+
Sbjct: 10972 QNLGATADSDGDSLSLQTLKKRISKKGIHGEAESKL---GEKQSGSDSFTLQDLYEELKA 11028
Query: 365 ENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKG-IENL--ESENKKL 421
K+D +E A+ DQ +K +E R+ ++ K G ENL ES +
Sbjct: 11029 -----KEDAVEAGAETSNADQSAEKTS--LEVRDMKKKMKKKQVSGTAENLIGESNRDET 11081
Query: 422 KKDIQEEQAQRKIEIEGKLEISNAFAALENE--VSALKSESTKLKKDILEEQAQ---IKV 476
+I++ Q + + F + E +K S KL + EE I
Sbjct: 11082 SMEIRDLNTQHSNQTGEDESSTFNFGQKDQEQYSMVMKDVSKKLARQNAEEIQSGKLIPT 11141
Query: 477 AIEEKLEIS------NAFAALENEVSALK-------SEIAALQQKCGAGSREGNGDVEVL 523
EEK ++ N ENE + + S +L + + G+VE
Sbjct: 11142 TNEEKTGLALTGKNKNLKKGEENEKTKFEAKHLGSSSASDSLAESTLRSKKTKKGEVEKS 11201
Query: 524 KAGISDTEKEVNTLKKELV-------------EKEKIVA--DSERKTAVDERKKAAAEAR 568
+ I ++ TL L+ E E +VA + E+ + RK+ + ++
Sbjct: 11202 ELSIDMKNQDKTTLATTLLEDDLAKTTSAEESEAEHLVALQNKEKTSLAMRRKRVSFDSS 11261
Query: 569 KLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESE 628
E+ + + P+K + + ++ +K E +N + K I + E +
Sbjct: 11262 TKSESIEDVIPDKNRDSDKMSITGIKKKMSQKSESAEAQKNESPEV-----KEISSFEEK 11316
Query: 629 NKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEE 688
K KK+ S + G A G+ ++ ++D + + + + E+
Sbjct: 11317 TLKSKKK----------SKADRNQGTEANLGDKTIDKDYLSVTDKNQSLEKSEASGQAEK 11366
Query: 689 RIVADSERKTAVDERKNAAAEARKLLEAPKKIA----AEVEK--QIAKVELRQVHLEKQV 742
I A ++ K + L A +++A AE EK + V + L K
Sbjct: 11367 SIKAPNKSKVTTSFADESLTSELDRLMADEEMAEMMFAEEEKAADLLNVMNKNKGLNKSE 11426
Query: 743 NERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAE-----SKIKKAQERSESELDKKTA 797
E +++ + + + + KK+ ++K + + SKI ++++ ++KT+
Sbjct: 11427 QEESQEISLKSQSKVKDSDSLSSTDKKIGLKKSDKDQKLGTSKIFGSKDQESVGYEEKTS 11486
Query: 798 DMEKQQ 803
+ KQ+
Sbjct: 11487 NFSKQR 11492
Score = 62.4 bits (150), Expect = 6e-08
Identities = 172/878 (19%), Positives = 331/878 (37%), Gaps = 144/878 (16%)
Query: 34 ALRQAVKILEKGIEN-LESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALI 92
+++Q K ++K EN ++ K K QE A+ ++ + +E ++
Sbjct: 10887 SIQQLNKSVKKKPENEAVTQGKSGKSQEQESDKMSIQALNKSMKKKDGVDGVEGNINIGR 10946
Query: 93 SENKKLK-QDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENL----ESENK 147
S+ +L DI E + + + + + +++ L+KRI E+E+K
Sbjct: 10947 SDGDQLSVNDIDAELSTSEQVENASQNLGATADSDGDSLSLQTLKKRISKKGIHGEAESK 11006
Query: 148 KLKK----------DIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILE 197
+K D+ EE ++ +E E SNA + E ++ KK+KK +
Sbjct: 11007 LGEKQSGSDSFTLQDLYEELKAKEDAVEAGAETSNADQSAEKTSLEVRDMKKKMKKKQVS 11066
Query: 198 EQAQRKVAMEGKLEISNAFAALENEVS-----------------------ALKSENKKLK 234
A+ + + E S L + S +K +KKL
Sbjct: 11067 GTAENLIGESNRDETSMEIRDLNTQHSNQTGEDESSTFNFGQKDQEQYSMVMKDVSKKLA 11126
Query: 235 QDILDEQAQGKFCDRL-KKKCEKVVEGRNALRQAVKILEKGIENLESE-------NKKLK 286
+ +E GK ++K + G+N K L+KG EN +++ +
Sbjct: 11127 RQNAEEIQSGKLIPTTNEEKTGLALTGKN------KNLKKGEENEKTKFEAKHLGSSSAS 11180
Query: 287 KDIQEEHAQRKVEIEGKLEISNAFAALENE-----VSALKSENKKLKKDILEEQAQRKVA 341
+ E + K +G++E S ++N+ + L ++ E +A+ VA
Sbjct: 11181 DSLAESTLRSKKTKKGEVEKSELSIDMKNQDKTTLATTLLEDDLAKTTSAEESEAEHLVA 11240
Query: 342 MEGKLEISNAFAALENEV-SALKSEN---------------------KKLKQDILEEQAQ 379
++ K + S A S+ KSE+ KK+ Q +AQ
Sbjct: 11241 LQNKEKTSLAMRRKRVSFDSSTKSESIEDVIPDKNRDSDKMSITGIKKKMSQKSESAEAQ 11300
Query: 380 ----------GKFCDQLKKKCEKVVEGRNALRQA---VKILEKGIENLESENKKLKKDIQ 426
F ++ K +K RN +A K ++K ++ +N+ L+K
Sbjct: 11301 KNESPEVKEISSFEEKTLKSKKKSKADRNQGTEANLGDKTIDKDYLSVTDKNQSLEKSEA 11360
Query: 427 EEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEK----L 482
QA++ I+ K +++ +FA +L SE +L D EE A++ A EEK L
Sbjct: 11361 SGQAEKSIKAPNKSKVTTSFAD-----ESLTSELDRLMAD--EEMAEMMFAEEEKAADLL 11413
Query: 483 EISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELV 542
+ N L EI+ Q S+ + D +S T+K++ K +
Sbjct: 11414 NVMNKNKGLNKSEQEESQEISLKSQ-----SKVKDSD------SLSSTDKKIGLKKSDKD 11462
Query: 543 EK---EKIVADSERKTAVDERKKA--AAEARKLLEAAKKIAPEKAVIPEPANCCSKCDEL 597
+K KI ++++ E K + + + R + + ++ + E S+ E+
Sbjct: 11463 QKLGTSKIFGSKDQESVGYEEKTSNFSKQRRGVSDLGSDAMTDQKNVQE-----SQYAEI 11517
Query: 598 KKKCEKVAVGRNALRQAVKILEKGIENLE-SENKKLKKENEVSALKSEISALQQKCGAGA 656
G + A + + G + + SE ++ K+ + + A C +
Sbjct: 11518 SADDHMSKTGADGEISATRTIVDGSDAAQGSEYAEISKKRKFKRAEQIGEAETSLC--DS 11575
Query: 657 REGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDE--------RKNAAA 708
RE D ISD E+ R E +I +E T++ + +K
Sbjct: 11576 RENTHD----SLSISDVNPELRRSNVEISAFGQIDLTAEEVTSLTDINKDAQLTKKQDEN 11631
Query: 709 EARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKK 768
+A+K + K A+ + + ++ K+ + R+ E ++ TK + +
Sbjct: 11632 DAKKSVSKNLKAGAKKDSDTLSITSKKDKFGKRQDSREASATVEQQGEEKVTKNLKGSRG 11691
Query: 769 KLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEE 806
K EK+ ++ I E E E T D+E +E+
Sbjct: 11692 K--KEKL-GDAGIDVNFENQE-EFASTTGDIESIVSEK 11725
Score = 60.5 bits (145), Expect = 2e-07
Identities = 157/726 (21%), Positives = 296/726 (40%), Gaps = 101/726 (13%)
Query: 3 SEKAVIPEPANCCSKCEELKKKCEQVVVGRNALRQAV---KILEKGIENLESENKKLKKD 59
++K PE S E+ K ++ RN +A K ++K ++ +N+ L+K
Sbjct: 11299 AQKNESPEVKEISSFEEKTLKSKKKSKADRNQGTEANLGDKTIDKDYLSVTDKNQSLEKS 11358
Query: 60 IQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE 119
QA++ + K +++ +FA +L SE +L D EE A+ ++ K +
Sbjct: 11359 EASGQAEKSIKAPNKSKVTTSFAD-----ESLTSELDRLMAD--EEMAEMMFAEEEKAAD 11411
Query: 120 KVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALEN 179
+ N+ ++NK L K QEE + ++ + K++ S++ ++ +
Sbjct: 11412 LL-------------------NVMNKNKGLNKSEQEESQEISLKSQSKVKDSDSLSSTDK 11452
Query: 180 EVSALKSE-NKKL-KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDI 237
++ KS+ ++KL I + Q V E K ++ F+ VS L S+ ++++
Sbjct: 11453 KIGLKKSDKDQKLGTSKIFGSKDQESVGYEEK---TSNFSKQRRGVSDLGSDAMTDQKNV 11509
Query: 238 LDEQ-AQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLE-SENKKLKKDIQEEHAQ 295
+ Q A+ D + K G + A + + G + + SE ++ K + + A+
Sbjct: 11510 QESQYAEISADDHMSK------TGADGEISATRTIVDGSDAAQGSEYAEISKKRKFKRAE 11563
Query: 296 RKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGK----LEISNA 351
+ E E L S ++ ++ N +L++ +E A ++ + + L N
Sbjct: 11564 QIGEAETSLCDSRENT---HDSLSISDVNPELRRSNVEISAFGQIDLTAEEVTSLTDINK 11620
Query: 352 FAAL---ENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEG-RNALRQAVKIL 407
A L ++E A KS +K LK ++ D L +K G R R+A +
Sbjct: 11621 DAQLTKKQDENDAKKSVSKNLKAGAKKDS------DTLSITSKKDKFGKRQDSREASATV 11674
Query: 408 EKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSE------ST 461
E+ E ++N K + +E+ I++ E FA+ ++ ++ SE S
Sbjct: 11675 EQQGEEKVTKNLKGSRGKKEKLGDAGIDV--NFENQEEFASTTGDIESIVSEKGHDTYSE 11732
Query: 462 KLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVE 521
K K ++ Q A E NA +AL + A L+ + G E +
Sbjct: 11733 KTVKSSKKKSPQTAGAEYGGSESLNASSAL-----STTDVDAQLKNQEKDGVAESSIGKS 11787
Query: 522 VLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEK 581
K S+ E VN KK+ V K + D A+ E+ ++A + A
Sbjct: 11788 NQKDSYSEQELNVNKKKKQAVGAAMNQGSGSTKES-DNLAVASVESNLAKDSANQEASLH 11846
Query: 582 AVIPEPANCCSKCD---ELKKKCEKVA----VGRN------ALRQAVKILEKGIENLESE 628
++ A S+ D LKK+ ++++ +G++ AL + L KG ++ ES
Sbjct: 11847 GLVDNDATSLSQLDSEHRLKKRDDELSAHTKLGKHTQSENIALTETDDSLVKG-DSEESA 11905
Query: 629 NKKLKKENEV-----------SALKSEISALQQKCGAGAREGNGD---VEVLKAGISDTK 674
+K++ E + LK + Q A +G D + V +GIS K
Sbjct: 11906 ELNIKQQGETAEDKYVESRKKTTLKKKPEQKQVTDTLSAVDGRHDTTSLSVADSGISFDK 11965
Query: 675 KEVNRL 680
N L
Sbjct: 11966 SMENEL 11971
Score = 45.8 bits (107), Expect = 0.006
Identities = 81/358 (22%), Positives = 140/358 (38%), Gaps = 69/358 (19%)
Query: 521 EVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKK---- 576
+++K + ++V + E + ++ S +T V +KK AE L AKK
Sbjct: 12573 KIIKKKETPESEQVTAAEPEQQKISEVDVQSVAETEVGAKKKPDAEKPTDLSKAKKDSKS 12632
Query: 577 --------IAPEKAVIPEPAN--CCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLE 626
EK+ +P N K E K K V L + +K +
Sbjct: 12633 KKSDEPEASTEEKSTTEKPTNDKTSKKSAEKKTVKPKKEVTGKPLEAKKPVEDKKDASQP 12692
Query: 627 SENK--------KLKKE--------NEVSALKSEISALQQKCG----AGAREGNGD---- 662
S +K K KK+ +E+S+ + S + + REG+ D
Sbjct: 12693 SSSKESSPPTDGKKKKQIPKALFIPDEISSRFGDPSTMHSETNITTTIRGREGSADAKTP 12752
Query: 663 -VEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDE--RKNAAAEARKLLEAPKK 719
VE L A +S +K E +E+ + R D+ RK K E +
Sbjct: 12753 LVEPLSASVS--------MKVESAKEKAEFSFKRRSETPDDKSRKKEGLPPAKKSEKKDE 12804
Query: 720 IAAEVEKQIAKVELRQVHLEKQVNERKM-------KLAFELSKTKEATKRFEAEKKKLLV 772
+ AE + A +E + +K+V+E K+ K E+ E E +K +
Sbjct: 12805 VTAEKQSTEALIESK----KKEVDESKISEQQPSDKNKSEVVGVPEKAAGPETKKDVSEI 12860
Query: 773 EKINAESKIKKAQERSESELDKKT-----ADMEKQQAEE----QKKLAEDKLLLLGDS 821
E++ + IKK E+S+S + +K+ AD +K ++++ KK ED+ + DS
Sbjct: 12861 EEVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSKKTTEDQTKVATDS 12918
Score = 40.4 bits (93), Expect = 0.24
Identities = 95/408 (23%), Positives = 169/408 (41%), Gaps = 85/408 (20%)
Query: 337 QRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEG 396
++KV LEI+N ++ K K L E G++ Q+ V
Sbjct: 14969 RKKVGDSDWLEIAN-------------TDRNKFKDRSLTES--GEYVYQVTATGIHAVSS 15013
Query: 397 RNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKI--EIEGKLEISNAFAALENEVS 454
+ VKIL G E S+ +K K D + ++++K EI + ++ + A+ E+
Sbjct: 15014 PSEETNPVKILVPGSEMPASKTEK-KTDAAKSESEQKSAEEIVAEKQVDQSQAS-ESTTE 15071
Query: 455 ALKSESTK--LKKDILEEQAQIKVA-IEEKLEISNAFAALENEVSALKSEIAALQQKCGA 511
A++ + TK +KK + E + + + ++EKL+ A +++E
Sbjct: 15072 AVEEKKTKKVVKKKVAENKGEETLQEVKEKLKKGKAVEKVQDE----------------- 15114
Query: 512 GSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLL 571
SR G+ L+A SD E T +K + ++ +SE+ E+K +A+ L
Sbjct: 15115 -SRRGS-----LQAS-SDNESVTTTSEKR--SEAELEKNSEKSA---EKKSTSAD----L 15158
Query: 572 EAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKK 631
EAA K EK+ + ++ KK +KVA +KG+ + +
Sbjct: 15159 EAADKAETEKSETGKETT-----EKKKKVVKKVA-------------KKGLVKADKSKIE 15200
Query: 632 LK--KENEVSALKSEIS-ALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEE 688
L KE E+SA +E +++ K A + + V G+S K + V
Sbjct: 15201 LTAGKEGEISAQVAETGVSVEWKKDGKALDASYTV-TSTGGVSTVKIPI-----VDVNTS 15254
Query: 689 RIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQV 736
+ + + DE + + A KL E PK E E+ I +V++ V
Sbjct: 15255 GVFTCKVKSSEGDEEEVSIAVTVKLPEVPK---VEAEQSIVEVKVGDV 15299
Score = 40.0 bits (92), Expect = 0.31
Identities = 136/735 (18%), Positives = 264/735 (35%), Gaps = 104/735 (14%)
Query: 130 QAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEK-----------------SN 172
Q +I+E++ E E K+L +++ E + E+ LE S
Sbjct: 4693 QPAEIVEQKDVTCEEEIKELLTEVEVELFFSQAEVFSGLELDLLMECSEYVTTSIQKGST 4752
Query: 173 AFAALENEVSALKS-ENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENK 231
A A E V L E+K+ + E ++K + + +E E
Sbjct: 4753 AAPAQEPTVEKLAPVESKETSEVEPAEIVEQKDVPVPETSAPSVEPTVEKLAPVESKETS 4812
Query: 232 KLKQDILDEQAQGKFCDRLKKKCEKVVEG-------RNALRQAVKILEKGIENLESENKK 284
+++Q + EQ + E VE + Q +I+E+ E E K+
Sbjct: 4813 EVQQAEIVEQKDVPVPETSAPSVEPTVEKLAPAESKETSEVQPAEIVEQKDVTCEEEIKE 4872
Query: 285 LKKDIQEEHAQRKVEIEGKLEISNAF-------AALENEVSALKSENKKLKKDILEEQAQ 337
L +++ E + E+ LE+ +++ +A ++ ++K E +
Sbjct: 4873 LLTEVEVELFFSQAEVFSGLELDLLMECSEYVTTSIQKGSTAAPAQEPTVEKLAPVESKE 4932
Query: 338 RKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGR 397
+ ++ E ++ +KLK +E ++ + + +++K V E
Sbjct: 4933 TSEVQQAEIIEQKDVPVPETSAPTVEPTVEKLKPVESKETSEVQQVEIIEQKDVPVPE-- 4990
Query: 398 NALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALK 457
+ +E +E L K ++Q+ + IE + + +E V LK
Sbjct: 4991 ----TSAPTVEPTVEKLAPVESKETSEVQQAEI---IEQKDVPVPETSAPTVEPTVEKLK 5043
Query: 458 SESTKLKKDILE----EQAQIKV------AIEEKLEISNAFAALENEVSALKSEIAALQQ 507
+K ++ + EQ + V +E +E A +E++ ++ + ++Q
Sbjct: 5044 PVESKETSEVQQVEIIEQKDVPVPETSAPTVEPTVE---KLAPVESKETSEVQQAEIIEQ 5100
Query: 508 KCGAGSREGNGDVEVLKAGISDTEKEVNTLK----KELVEKEKIVADSERKTAVDE---- 559
K DV V + E V LK KE E +++ ++ V E
Sbjct: 5101 K----------DVPVPETSAPTVEPTVEKLKPVESKETSEVQQVEIIEQKDVPVPETSAP 5150
Query: 560 ------RKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQ 613
K A E+++ E E+ V+P P + +K V Q
Sbjct: 5151 TVEPTVEKHAPVESKETSEVQPAEIVEQKVVPVPETSAPTVEPTVEKLAPVESKETPEVQ 5210
Query: 614 AVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDT 673
+ILE+ E E K+L E EV S+ EV D
Sbjct: 5211 PAEILEQKDVTCEEEIKELLTEVEVELFFSK------------------AEVFSGLELDL 5252
Query: 674 KKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVEL 733
E + +++ A ++ T K A E+++ E E +K + E
Sbjct: 5253 LMECSEYVTTSIQKGSTAAPAQEPTV---EKLAPVESKETSEVEPAEIVE-QKDVPVPET 5308
Query: 734 RQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELD 793
+E V + K + E +T E + E+K + V + +A + ++ E+
Sbjct: 5309 SAPTVEPTVEKLK---SVESKETSEVQQAEIIEQKDVPVPETSAPT-VEPTVEKLAPVDS 5364
Query: 794 KKTADMEKQQAEEQK 808
K+T+++E + EQK
Sbjct: 5365 KETSEVEPAEIVEQK 5379
Score = 38.9 bits (89), Expect = 0.69
Identities = 82/334 (24%), Positives = 145/334 (42%), Gaps = 40/334 (11%)
Query: 33 NALRQAV--KILEKGIENLESE-NKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVS 89
N L+Q K+ ++ + L+ E + KLKKD ++++ +++ + K E + L+ E
Sbjct: 8323 NKLKQEADAKLKKEKDDKLKQEADAKLKKD-KDDKLKQEADAKLKKEKDDK---LKQEAD 8378
Query: 90 ALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESE-NKK 148
A + KK K D L+++A K+ + K +K+ + +A K+ + + + L+ E + K
Sbjct: 8379 AKL---KKEKDDKLKQEADAKL--KKDKDDKLKQEADA-----KLKKDKDDKLKQEADAK 8428
Query: 149 LKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEG 208
LKK E+ + K E + KL+K L+ E A + KK K D L+++A K+ E
Sbjct: 8429 LKK---EKDDKLKQEADAKLKKDKD-DKLKQEADA---KLKKDKDDKLKQEADAKLKKEK 8481
Query: 209 ----KLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGR--- 261
KLE + + E S + K KQ + C+R+ E+
Sbjct: 8482 GDKLKLEDQTNQSRIFEETSIEVTSLLKCKQQAIIVSKSFALCERVVLNAEEPFTLEVFC 8541
Query: 262 NALRQAVKILEKGIENLESENKKLKKDIQEEHAQR------KVEIEGKLEISNAFAALEN 315
NA+ + + GI + + KKD E R ++ L I + +
Sbjct: 8542 NAVFVKQRTDKIGIGIIFERSGASKKD--ESRPDRLDDNCVLTDVTDGLSILSPPPKAKK 8599
Query: 316 EVSALKSENKKLKKDILEEQAQRKVAMEGKLEIS 349
+ K +KK K + E + K K EIS
Sbjct: 8600 HLKKKKKHHKKEKIAVKETEQDEKTVSHLKPEIS 8633
Score = 37.7 bits (86), Expect = 1.5
Identities = 52/273 (19%), Positives = 124/273 (45%), Gaps = 26/273 (9%)
Query: 294 AQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFA 353
A+ K E+E + + E+ + KK+I+ ++ Q+ +++ +++++
Sbjct: 1967 AKAKGEVENLKKCVETLLLFDAEMDMKDIKESSPKKEIISKKDQQ--SLDDQIKVTQQIL 2024
Query: 354 A-LENEVSALK--------SENKKL--KQDILE-EQAQGKFCDQLKKKCEKVVEGRNALR 401
+E +++ ++ S NK+ +D+ + E A DQL + R AL+
Sbjct: 2025 KDVERDLNKMERTSPGKSLSPNKRTFAPKDVEDIEAAIFSISDQLADRQSSEEALREALQ 2084
Query: 402 QAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKL-------EISNAFAALENEVS 454
+ + ++ L N+ K ++ + + Q+ E+E K+ ++ A +A+EN +
Sbjct: 2085 EMILSNSSPMKELSRNNETSKPEVLKSEIQKIPEVETKISEVYPIVKLKQAISAIENSLL 2144
Query: 455 ALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKC---GA 511
+E T++ K ++ + K +++ +++ A + S L+ + L Q +
Sbjct: 2145 E-DTEVTEIMKRKGSDKDKRKATRIKRVPSAHS-ARITPITSNLRDRLNQLHQLTVSEDS 2202
Query: 512 GSREGNGDVEVLKAGISDTEKEVNTLKKELVEK 544
GS + N + + ++ EKE+NT+ + EK
Sbjct: 2203 GSLKQNEEAKEIQELFVKIEKEINTIAELCKEK 2235
Score = 37.4 bits (85), Expect = 2.0
Identities = 59/301 (19%), Positives = 123/301 (40%), Gaps = 21/301 (6%)
Query: 529 DTEKEVNTLKKELVEKEKIVADSERKTAVDERKK--AAAEARKLLEAAKKIAPEKAVIPE 586
D+++ E+VE++ + T V+ K+ A E+++ E + E+ +
Sbjct: 6699 DSKETSEVQTAEIVEQKDVPVPETSATTVEPTKEKLAPGESKETSEVQQAAIVEQKDVAV 6758
Query: 587 PANCCSKCDELKKKCEKVAVGRNALRQAVKILEK--------GIENLESENKKLKK-ENE 637
P + + K+K V + Q +I+E+ +E +KL E++
Sbjct: 6759 PETSATTVEPTKEKLAPVESKETSEIQTAEIVEQKDVPVPETSTSYVEPTKEKLAPGESK 6818
Query: 638 VSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTK-KEVNRLKKEHVEEERIVADSER 696
++ + + ++QK VE K ++ + KE + +++ V E++ V E
Sbjct: 6819 ETSEVQQAAIVEQKDVPVPETSATTVEPTKEKLAPVESKETSEIQQAAVVEQKDVPVPET 6878
Query: 697 KTAVDE---RKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLA-FE 752
E K A E+++ E + E +K + E E V KLA E
Sbjct: 6879 SATTVEPTKEKLAPVESKETSEVQQAAIVE-QKDVPVPEANAPTFEPTVE----KLAPVE 6933
Query: 753 LSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAE 812
+T E + E+K + V + NA + ++ + E + + + ++ QA+ + K +
Sbjct: 6934 SKETSEVQQAAIVEQKDVPVPEANAPTVEPTVEKLAPVESKETSVESKETQADAKLKKEK 6993
Query: 813 D 813
D
Sbjct: 6994 D 6994
Score = 37.0 bits (84), Expect = 2.6
Identities = 43/205 (20%), Positives = 88/205 (41%), Gaps = 14/205 (6%)
Query: 622 IENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAG----ISDTKKEV 677
I N + K + E +++A + E V++L G S T+K+
Sbjct: 14980 IANTDRNKFKDRSLTESGEYVYQVTATGIHAVSSPSEETNPVKILVPGSEMPASKTEKKT 15039
Query: 678 NRLKKEHVEE--ERIVADSE-RKTAVDERKNAAAEARKLLEAPKKIAAEVEK----QIAK 730
+ K E ++ E IVA+ + ++ E A E +K + KK AE + Q K
Sbjct: 15040 DAAKSESEQKSAEEIVAEKQVDQSQASESTTEAVEEKKTKKVVKKKVAENKGEETLQEVK 15099
Query: 731 VELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSES 790
+L++ ++V + + + + S E+ ++ + +EK + +S KK+
Sbjct: 15100 EKLKKGKAVEKVQDESRRGSLQASSDNESVTTTSEKRSEAELEKNSEKSAEKKSTSADLE 15159
Query: 791 ELDK---KTADMEKQQAEEQKKLAE 812
DK + ++ K+ E++KK+ +
Sbjct: 15160 AADKAETEKSETGKETTEKKKKVVK 15184
Score = 36.2 bits (82), Expect = 4.5
Identities = 63/280 (22%), Positives = 109/280 (38%), Gaps = 76/280 (27%)
Query: 527 ISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPE 586
+S +E N +K +V SE + E+K AA++ ++A++I EK V
Sbjct: 15011 VSSPSEETNPVKI-------LVPGSEMPASKTEKKTDAAKSESEQKSAEEIVAEKQVDQS 15063
Query: 587 PANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEIS 646
A+ + +KK +KV + A KG E L+ +KLKK V ++ E
Sbjct: 15064 QASESTTEAVEEKKTKKVVKKKVAEN-------KGEETLQEVKEKLKKGKAVEKVQDE-- 15114
Query: 647 ALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNA 706
+R G+ L+A + E + SE+++ + KN+
Sbjct: 15115 ---------SRRGS-----LQASS---------------DNESVTTTSEKRSEAELEKNS 15145
Query: 707 AAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAE 766
A K K +A++E A + K T + E
Sbjct: 15146 EKSAEK-----KSTSADLEA-----------------------ADKAETEKSETGKETTE 15177
Query: 767 KKKLLVEKINAESKIKKAQERSESELDK-KTADMEKQQAE 805
KKK +V+K+ + +K ++S+ EL K ++ Q AE
Sbjct: 15178 KKKKVVKKVAKKGLVK--ADKSKIELTAGKEGEISAQVAE 15215
>gb|AAN61517.1| 2MDa_1 protein [Caenorhabditis elegans]
Length = 18534
Score = 149 bits (377), Expect = 3e-34
Identities = 215/841 (25%), Positives = 376/841 (44%), Gaps = 126/841 (14%)
Query: 4 EKAVIPEPANCCSKCEELKKKC---EQVVVGRNALRQAVKILEKGIENLESENKKLKKDI 60
EKA PE S+ EE+ KK ++ +++ Q +L+ ++ + K
Sbjct: 12846 EKAAGPETKKDVSEIEEVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSK 12905
Query: 61 QEEQAQRKVAIEGKLE-ISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE 119
+ + Q KVA + KLE ++T +E E ++ + K K + + Q +
Sbjct: 12906 KTTEDQTKVATDSKLEKAADTTKQIETET--VVDDKSKKKVLKKKTEKSDSFISQKSETP 12963
Query: 120 KVVEG-RNALRQAVKILE-------KRIE-NLESENKKLKKDIQEEQAQRKIEIEGKLEK 170
VVE + A +A KI E K ++ NL+ E + K I +E+ KIE E ++K
Sbjct: 12964 PVVEPTKPAESEAQKIAEVNKAKKQKEVDDNLKREAEVAAKKIADEKL--KIEAEANIKK 13021
Query: 171 SNAFAALENEVSALKSENKKLKKDILEEQ-AQRKVAMEGKLEISNAFAALENEVSALKSE 229
+ A + + K E KL+ +++ ++ A K+ +E + +I A E A+K +
Sbjct: 13022 TAEVEAAKKQKE--KDEQLKLETEVVSKKSAAEKLELEKQAQIKKAA-----EADAVKKQ 13074
Query: 230 NKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDI 289
K+L + E A+ D+LK + E + + ++VK E E + K +K +
Sbjct: 13075 -KELNEKNKLEAAKKSAADKLKLEEESAAKSKKVSEESVKFGE------EKKTKAGEKTV 13127
Query: 290 Q-EEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEI 348
Q E K I+ K +V A + ++ KK I++++ ++ + I
Sbjct: 13128 QVESEPTSKKTIDTK------------DVGATEPADETPKKKIIKKKTEKSDS-----SI 13170
Query: 349 SNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILE 408
S A +VS K +++ K + E Q + D+ KK+ E + + A K +
Sbjct: 13171 SQKSATDSEKVSKQKEQDEPTKPAVSETQMVTE-ADKSKKQKETDEKLKLDAEIAAKTKQ 13229
Query: 409 KGIENLESE-NKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDI 467
+ E + + +K+KK +++ A+++ E+ KL+ LE+E++ K+ + KLK
Sbjct: 13230 EADEKSKLDAQEKIKKVSEDDAARKEKELNDKLK-------LESEIATKKASADKLK--- 13279
Query: 468 LEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGI 527
LEEQAQ K A E + A + + LK + A +K A E ++ KA
Sbjct: 13280 LEEQAQAKKAAEVE-----AAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAG 13334
Query: 528 SDTEKEVNTLKKELVEKEKIVADSERKTAVD----ERKKAAAEARKLLEAAKKIAPEKAV 583
+D K+ +KEL EK K+ A+ +K+A E + AA + + E AK A KA
Sbjct: 13335 ADAVKK----QKELDEKNKLEAN--KKSAAGKLKIEEESAAKSKQTVEEQAKLDAQTKAK 13388
Query: 584 IPEPANCCSKCDELKKKCE-KVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALK 642
E K ++ K+ E K V ++ +K KK +K + + K
Sbjct: 13389 TAEKQTKLEKDEKSTKESESKETVDEKPKKKVLK-------------KKTEKSDSSISQK 13435
Query: 643 SEISALQQKCGAGAREGNGDVEVLKAGISDTKK--EVNRLKKEHVEEERIVADSERKTAV 700
SE S + AG E S+T+K + R +KE E++++ A+ K +
Sbjct: 13436 SETSKTVVE-SAGPSE------------SETQKVADAARKQKETDEKQKLEAEITAKKSA 13482
Query: 701 DERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEAT 760
DE+ AE++ K+ A+VE + EK + ++KL E + K A
Sbjct: 13483 DEKSKLEAESKL-------------KKAAEVEAAKKQKEK---DEQLKLDTEAASKKAAA 13526
Query: 761 KRFEAEKKKLL--VEKINAESKIKKAQE--RSESELDKKTADMEKQQAEEQKKLAEDKLL 816
++ E EK+ + +++A K K+ +E R ESE K AD EK + EEQKK A + L
Sbjct: 13527 EKLELEKQSHIKKAAEVDAVKKQKELEEKQRLESEAATKKADAEKLKLEEQKKKAAEIAL 13586
Query: 817 L 817
+
Sbjct: 13587 I 13587
Score = 140 bits (354), Expect = 1e-31
Identities = 206/817 (25%), Positives = 376/817 (45%), Gaps = 93/817 (11%)
Query: 37 QAVKILEKGIENLESENK-KLKKDI---QEEQAQRKVAIEGKLEISNTFAALENEVSALI 92
Q V ++K + E++ K KL+ +I + + + K+ E KL+ + A + +
Sbjct: 9368 QNVAAVDKEKKQKETDEKQKLEAEIAGKKSTEQKSKLEAEAKLKRAAEEDAAKKQKEKTE 9427
Query: 93 SENKKLKQDILEEQAQGKI-----CDQLKKCEKVVEGRNALRQAVKILEKRIENLESENK 147
+ +KK + LE + Q +I D +KK ++ E +N L K+ ++++ LE ++
Sbjct: 9428 AASKKAAAEKLELEKQAQINKAAEADAVKKQNELDE-QNKLEATKKLAAEKLK-LEEQSA 9485
Query: 148 KLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAME 207
K EEQA K++ + K + + LE + KS + +EE+ ++KV ++
Sbjct: 9486 AKSKQAAEEQA--KLDAQTKAKAAEKQTGLEKDE---KSNKDSGSNETVEEKPKKKV-LK 9539
Query: 208 GKLEISNAFAALENEVSALKSEN----KKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNA 263
K E S++ + +++ S +E+ + Q + D ++ K D+ K+K E + + +
Sbjct: 9540 KKTEKSDSSISQKSDTSKTVAESAGSSESETQKVADATSKQKETDK-KQKLEAEITAKKS 9598
Query: 264 LRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSE 323
+ K LE+E+K +K E+ A+++ E E KL+ LE +V++ K+
Sbjct: 9599 ADEKSK--------LETESKLIKA--AEDAAKKQKEKEDKLK-------LEADVASKKAA 9641
Query: 324 NKKLKKDILEEQAQRKVAMEGKLEISNAFAA----LENEVSALKSENKKLKQDILEEQAQ 379
+KL+ LE+QAQ K A E A LE+E + K+ +KLK LEEQAQ
Sbjct: 9642 AEKLE---LEKQAQIKKAAEADAVKKQKELAEKQKLESEAATKKAAAEKLK---LEEQAQ 9695
Query: 380 -GKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEG 438
K + K +K ++ +N L K E L+ E + K Q + Q K++ +
Sbjct: 9696 INKAAEADAVKKQKELDEKNKLEANKK---SAAEKLKLEEESAAKSKQTVEEQAKLDAQT 9752
Query: 439 KLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSAL 498
K + + LE + + K +K + ++E+ + KV +++K E S++ + ++ S
Sbjct: 9753 KEKTAEKQTGLEKDDKSTKDSESK---ETVDEKPKKKV-LKKKTEKSDSSISQKSVTSKT 9808
Query: 499 KSEIAALQ----QKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERK 554
E QK +R+ E K E E+ T KK EK K+ A+S+ K
Sbjct: 9809 VVESGGPSESETQKVADAARKQKETDEKQKL-----EAEI-TAKKSADEKSKLEAESKLK 9862
Query: 555 TAV-----------DERKKAAAEARKLLEAAKKIAPEK-AVIPEPA--NCCSKCDEL--K 598
A DE+ K EA AA+K+ EK A I + A + K EL K
Sbjct: 9863 KAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAEADAVKKEKELAEK 9922
Query: 599 KKCEKVAVGRNALRQAVKILEKGIENLES-------ENKKLKKENEVSALKSEISALQQK 651
+K E A + A + +K+ E+ ++ E+ E +KL +E + ++ SA +QK
Sbjct: 9923 QKLESEAATKKAAAEKLKLEEQKKKDAETASIEKQKEQEKLAQEQSKLEVDAKKSAEKQK 9982
Query: 652 CGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEAR 711
+ + + ++ KK+V + K E + KT + + +E +
Sbjct: 9983 LESETKSKKTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSDTAKTVAESAGQSDSETQ 10042
Query: 712 KLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLL 771
K+ EA K A + ++ K +L K+ E+K KL E +KTK+ + A+K+K
Sbjct: 10043 KVSEADK--AHKQKESDEKQKLESEIAAKKSAEQKSKLETE-AKTKKVIEDESAKKQKEQ 10099
Query: 772 VEKINAESKIKKAQERSESELDKKTADMEKQQAEEQK 808
+K + KK +++ E + + A +K +E+QK
Sbjct: 10100 EDKKKGDDSAKKQKDQKEKQKLESEATSKKPTSEKQK 10136
Score = 140 bits (353), Expect = 2e-31
Identities = 212/849 (24%), Positives = 362/849 (41%), Gaps = 114/849 (13%)
Query: 9 PEPANCCSKCEELKKKCEQVVVGRNALRQAVKILEKG-IENLESENKKLKKDIQE----- 62
P+P +V + + +A K+ EK LES++K + +E
Sbjct: 9267 PQPGGKSDSSISSTSDASEVKQVQQSESEAQKVTEKPETAKLESKSKMTEDTTKESDNKE 9326
Query: 63 --EQAQRKVAIEGKLEISNTFAALENEVSALIS----ENKKLKQDILEEQAQGKICDQLK 116
++ +K ++ K E S++ + +E SA+ S E++ ++++ + K D+ +
Sbjct: 9327 TVDEKPKKKVLKKKTEKSDSTISETSETSAVESAGPSESETQNVAAVDKEKKQKETDEKQ 9386
Query: 117 KCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAA 176
K E + G+ + Q K LE+E KLK+ +E+ A+++ E K A
Sbjct: 9387 KLEAEIAGKKSTEQKSK--------LEAE-AKLKRAAEEDAAKKQKEKTEAASKKAAAEK 9437
Query: 177 LENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALE---NEVSALKSENKKL 233
LE E A NK + D +++Q ++ + KLE + AA + E SA KS+
Sbjct: 9438 LELEKQA--QINKAAEADAVKKQ--NELDEQNKLEATKKLAAEKLKLEEQSAAKSKQAAE 9493
Query: 234 KQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEH 293
+Q LD Q + K ++ + G+E E NK + E
Sbjct: 9494 EQAKLDAQTKAKAAEK----------------------QTGLEKDEKSNKDSGSNETVEE 9531
Query: 294 AQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFA 353
+K ++ K E S++ + +++ S +E+ E + Q+ K + ++
Sbjct: 9532 KPKKKVLKKKTEKSDSSISQKSDTSKTVAESAGSS----ESETQKVADATSKQKETDKKQ 9587
Query: 354 ALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIEN 413
LE E++A KS ++K K + E + D KK+ EK E + L V + E
Sbjct: 9588 KLEAEITAKKSADEKSKLET-ESKLIKAAEDAAKKQKEK--EDKLKLEADVASKKAAAEK 9644
Query: 414 LESENK-KLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQA 472
LE E + ++KK + + +++ E+ K + LE+E + K+ + KLK LEEQA
Sbjct: 9645 LELEKQAQIKKAAEADAVKKQKELAEKQK-------LESEAATKKAAAEKLK---LEEQA 9694
Query: 473 QIKVAIEEKLEISNAFAALENEVSALKSEIAA---LQQKCGAGSREGNGDVEVLKAGISD 529
QI A E +N++ A K A L+++ A S++ + L A +
Sbjct: 9695 QINKAAEADAVKKQKELDEKNKLEANKKSAAEKLKLEEESAAKSKQTVEEQAKLDAQTKE 9754
Query: 530 TEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEA----AKKIAPEKAVI- 584
E T L + +K DSE K VDE+ K +K ++ ++K K V+
Sbjct: 9755 KTAEKQT---GLEKDDKSTKDSESKETVDEKPKKKVLKKKTEKSDSSISQKSVTSKTVVE 9811
Query: 585 ---PEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSA- 640
P + D +K+ E + K LE+E+K LKK EV A
Sbjct: 9812 SGGPSESETQKVADAARKQKETDEKQKLEAEITAKKSADEKSKLEAESK-LKKAAEVEAA 9870
Query: 641 ---------LKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIV 691
LK + A +K A E ++ KA +D K+ +KE E++++
Sbjct: 9871 KKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAEADAVKK----EKELAEKQKL- 9925
Query: 692 ADSERKTAVDERKNAAAEARKLLEAPKKIA--AEVEKQIAKVELRQ------VHLEKQVN 743
+SE T K AAAE KL E KK A A +EKQ + +L Q V +K
Sbjct: 9926 -ESEAAT-----KKAAAEKLKLEEQKKKDAETASIEKQKEQEKLAQEQSKLEVDAKKSAE 9979
Query: 744 ERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQ 803
++K++ + KT+EA K EK K V K E ++S++ K A+ Q
Sbjct: 9980 KQKLESETKSKKTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSDTA--KTVAESAGQS 10037
Query: 804 AEEQKKLAE 812
E +K++E
Sbjct: 10038 DSETQKVSE 10046
Score = 139 bits (351), Expect = 3e-31
Identities = 207/836 (24%), Positives = 360/836 (42%), Gaps = 117/836 (13%)
Query: 40 KILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLK 99
KI++K E +S + + + ++ Q K + E + T ++++EV K K
Sbjct: 9202 KIMKKKTEKADSSISETSETLTKDLTQTKQS-EPEPAKRTTETSVQDEVKRKTETTSKSK 9260
Query: 100 QDILEEQAQGKICDQ----LKKCEKVVEGRNALRQAVKILEK-RIENLESENKKLK---- 150
Q E G D +V + + + +A K+ EK LES++K +
Sbjct: 9261 QTTEEHPQPGGKSDSSISSTSDASEVKQVQQSESEAQKVTEKPETAKLESKSKMTEDTTK 9320
Query: 151 ----KDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAM 206
K+ +E+ ++K+ ++ K EKS++ + +E SA++S E Q V
Sbjct: 9321 ESDNKETVDEKPKKKV-LKKKTEKSDSTISETSETSAVESAGPSES----ETQNVAAVDK 9375
Query: 207 EGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKV-VEGRNALR 265
E K + ++ LE E++ KS +K K + + + D KK+ EK + A
Sbjct: 9376 EKKQKETDEKQKLEAEIAGKKSTEQKSKLEAEAKLKRAAEEDAAKKQKEKTEAASKKAAA 9435
Query: 266 QAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENK 325
+ +++ ++ N +E +KK Q +++ + KLE + AA E L+ ++
Sbjct: 9436 EKLELEKQAQINKAAEADAVKK-------QNELDEQNKLEATKKLAA---EKLKLEEQSA 9485
Query: 326 KLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQ 385
K EEQA K+ + K + + LE + KS + +EE+ + K
Sbjct: 9486 AKSKQAAEEQA--KLDAQTKAKAAEKQTGLEKDE---KSNKDSGSNETVEEKPKKKV--- 9537
Query: 386 LKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNA 445
LKKK EK + K + + + ESE +K+ +++ K +
Sbjct: 9538 LKKKTEKSDSSISQKSDTSKTVAESAGSSESETQKVADATSKQKETDKKQ---------- 9587
Query: 446 FAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAAL 505
LE E++A KS K K LE ++++ A E+ A + + LK E
Sbjct: 9588 --KLEAEITAKKSADEKSK---LETESKLIKAAED------AAKKQKEKEDKLKLEADVA 9636
Query: 506 QQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKA-- 563
+K A E ++ KA +D K+ +KEL EK+K+ +++ K A E+ K
Sbjct: 9637 SKKAAAEKLELEKQAQIKKAAEADAVKK----QKELAEKQKLESEAATKKAAAEKLKLEE 9692
Query: 564 ------AAEA-----------RKLLEAAKKIAPEKAVIPEPANCCSK--CDELKK----K 600
AAEA + LEA KK A EK + E + SK +E K
Sbjct: 9693 QAQINKAAEADAVKKQKELDEKNKLEANKKSAAEKLKLEEESAAKSKQTVEEQAKLDAQT 9752
Query: 601 CEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAR--E 658
EK A + L + K K E+ E+ ++K KK+ + S++ QK E
Sbjct: 9753 KEKTAEKQTGLEKDDKST-KDSESKETVDEKPKKKVLKKKTEKSDSSISQKSVTSKTVVE 9811
Query: 659 GNGDVEVLKAGISDTKK--EVNRLKKEHVEEERIVADSERKTAVDERKNAAAE------- 709
G E S+T+K + R +KE E++++ A+ K + DE+ AE
Sbjct: 9812 SGGPSE------SETQKVADAARKQKETDEKQKLEAEITAKKSADEKSKLEAESKLKKAA 9865
Query: 710 ----ARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEA 765
A+K E +++ + E K ++ LEKQ +K A + K KE A
Sbjct: 9866 EVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAEADAVKKEKEL-----A 9920
Query: 766 EKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAEDKLLLLGDS 821
EK+KL E ++ +K + + + D +TA +EKQ +EQ+KLA+++ L D+
Sbjct: 9921 EKQKLESEAATKKAAAEKLKLEEQKKKDAETASIEKQ--KEQEKLAQEQSKLEVDA 9974
Score = 127 bits (319), Expect = 1e-27
Identities = 211/867 (24%), Positives = 374/867 (42%), Gaps = 135/867 (15%)
Query: 22 KKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTF 81
K+K E + G+ + Q K+ + +E KK ++ +A K A KLE+
Sbjct: 9385 KQKLEAEIAGKKSTEQKSKLEAEAKLKRAAEEDAAKKQKEKTEAASKKAAAEKLELEK-- 9442
Query: 82 AALENEVSALISENKKLKQDILEEQ----AQGKICDQLKKCEK--VVEGRNALRQAVKI- 134
+ +++ + KQ+ L+EQ A K+ + K E+ + + A + K+
Sbjct: 9443 ---QAQINKAAEADAVKKQNELDEQNKLEATKKLAAEKLKLEEQSAAKSKQAAEEQAKLD 9499
Query: 135 -------LEKR--IENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALK 185
EK+ +E E NK + E+ +K ++ K EKS++ + +++ S
Sbjct: 9500 AQTKAKAAEKQTGLEKDEKSNKDSGSNETVEEKPKKKVLKKKTEKSDSSISQKSDTSKTV 9559
Query: 186 SENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGK 245
+E+ E + Q+ K + ++ LE E++A KS ++K K + + +
Sbjct: 9560 AESAGSS----ESETQKVADATSKQKETDKKQKLEAEITAKKSADEKSKLETESKLIKAA 9615
Query: 246 FCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENK-KLKKDIQEEHAQRKVEIEGKL 304
D KK+ EK E + L V + E LE E + ++KK + + +++ E+ K
Sbjct: 9616 E-DAAKKQKEK--EDKLKLEADVASKKAAAEKLELEKQAQIKKAAEADAVKKQKELAEKQ 9672
Query: 305 EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEG-------------KLEISNA 351
+ LE+E + K+ +KLK LEEQAQ A E KLE +
Sbjct: 9673 K-------LESEAATKKAAAEKLK---LEEQAQINKAAEADAVKKQKELDEKNKLEANKK 9722
Query: 352 FAALE---NEVSALKSENKKLKQDILEEQAQGKFCDQ---LKK--KCEKVVEGRNAL--R 401
AA + E SA KS+ +Q L+ Q + K ++ L+K K K E + + +
Sbjct: 9723 SAAEKLKLEEESAAKSKQTVEEQAKLDAQTKEKTAEKQTGLEKDDKSTKDSESKETVDEK 9782
Query: 402 QAVKILEKGIENLES---ENKKLKKDI------QEEQAQRKIEIEGKLEISNAFAALENE 452
K+L+K E +S + K + E + Q+ + K + ++ LE E
Sbjct: 9783 PKKKVLKKKTEKSDSSISQKSVTSKTVVESGGPSESETQKVADAARKQKETDEKQKLEAE 9842
Query: 453 VSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAG 512
++A KS K K LE ++++K A E + A + + LK + A +K A
Sbjct: 9843 ITAKKSADEKSK---LEAESKLKKAAEVE-----AAKKQKEKDEQLKLDTEAASKKAAAE 9894
Query: 513 SREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLE 572
E ++ KA +D K+ +KEL EK+K+ +SE T KKAAAE KL E
Sbjct: 9895 KLELEKQAQIKKAAEADAVKK----EKELAEKQKL--ESEAAT-----KKAAAEKLKLEE 9943
Query: 573 AAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALR-QAVKILEKGIENLESENKK 631
KK A ++ E +K+ EK+A ++ L A K EK + LESE K
Sbjct: 9944 QKKKDAETASI------------EKQKEQEKLAQEQSKLEVDAKKSAEK--QKLESETKS 9989
Query: 632 LKKEN------------EVSALKSEIS--ALQQKCGAGAR----EGNGDVEVLKAGISDT 673
K E +V K+E S ++ QK G D E K +D
Sbjct: 9990 KKTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSDTAKTVAESAGQSDSETQKVSEADK 10049
Query: 674 KKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVEL 733
+ +KE E++++ ++ K + +++ EA+ + A + ++Q K +
Sbjct: 10050 AHK----QKESDEKQKLESEIAAKKSAEQKSKLETEAKTKKVIEDESAKKQKEQEDKKKG 10105
Query: 734 RQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKI------KKAQER 787
+++ + K KL E + K +++ + EK EK +E++ ++ + +
Sbjct: 10106 DDSAKKQKDQKEKQKLESEATSKKPTSEKQKDEKTP--QEKAKSENETVMTTEPQQLEVK 10163
Query: 788 SESELDKKTADMEKQQAEEQKKLAEDK 814
SE + KT +EK+ A +K + K
Sbjct: 10164 SEPKKSDKTETVEKEVASSTEKSDDSK 10190
Score = 127 bits (318), Expect = 2e-27
Identities = 198/795 (24%), Positives = 365/795 (45%), Gaps = 77/795 (9%)
Query: 57 KKDIQEEQAQRKVA---IEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICD 113
+KD+ +A +E + + ++E++ + ++ KK K D +++A K+
Sbjct: 6948 QKDVPVPEANAPTVEPTVEKLAPVESKETSVESKETQADAKLKKEKDDKHKQEADAKL-- 7005
Query: 114 QLKKCEKVVEGRNALRQAVKILEKRIENLESE-NKKLKKDIQEEQAQRKIEIEGKLEKSN 172
Q + +K+ + +A K+ ++ + L+ E + KLKK+ ++ Q E + KL+K N
Sbjct: 7006 QKENDDKLKQEADA-----KLKKENDDKLKQEADAKLKKENDDKLKQ---EADAKLKKEN 7057
Query: 173 AFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKK 232
+ + LK EN D L+++A K+ E ++ E + K + K
Sbjct: 7058 DDKLKQEAAAKLKKEND----DKLKQEADAKLKKENDDKLKQ-----EADAKLQKENDDK 7108
Query: 233 LKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENK-KLKKDIQE 291
LKQ+ D + Q + D+LK++ + ++ N K+ ++ L+ EN KLK QE
Sbjct: 7109 LKQEA-DAKLQKENDDKLKQEADAKLQKEND----DKLKQEADAKLQKENDDKLK---QE 7160
Query: 292 EHAQRKVEIEGKL-EISNAFAALENEVSALKSENKKLKK---DILEEQAQRKVAMEGKLE 347
A+ + E + KL + ++A EN+ + + KLKK D L+++A K+ E +
Sbjct: 7161 ADAKLQKENDDKLKQEADAKLKKENDDKLKQEADAKLKKEKHDKLKQEADAKLQKENDDK 7220
Query: 348 ISN-AFAALENEVS-ALKSEN----KKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALR 401
+ A A L+ E LK E +K K D L+++A K K+K +K+ + +A
Sbjct: 7221 LKQEADAKLQKENDDKLKQEADAKLQKEKDDKLKQEADAKL---KKEKDDKLKQDADAKL 7277
Query: 402 QAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSEST 461
Q K +K + +++ KK K D + +A K++ E ++ E + K +
Sbjct: 7278 QKEKD-DKLKQEADAKLKKEKDDKLKHEADAKLQKEKDDKLKQ-----EADAKLKKEKDD 7331
Query: 462 KLKKDILEEQAQIKVAIEEKLEISNAFAALENEVS-ALKSEIAALQQKCGAGSREGNGDV 520
+LKKD A+++ ++KL+ A A L+ E LK E A QK + D
Sbjct: 7332 RLKKDA---DAKLQKEKDDKLK-QEADAKLKKEKDDKLKHEADAKLQKEKDDKLKQEADA 7387
Query: 521 EVLKAGISDTEKEVNT-LKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAP 579
++ K ++E + L+KE +K K AD++ K D++ K A+A+ E K+
Sbjct: 7388 KLKKEKDDKLKQEADAKLQKEKDDKLKQEADAKLKKEKDDKLKQEADAKLQKEKDDKLKQ 7447
Query: 580 EKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESE-NKKLKKENEV 638
E + E K +K + K+ ++ + L+ E + KLKKE +
Sbjct: 7448 EADAKLKKEKDDKLKQEADAKLQKEKDDKLKQEADAKLKKEKDDKLKQEADAKLKKEKD- 7506
Query: 639 SALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVN-RLKKEHVEEERIVADSERK 697
LK + A QK + D ++ K K E + +LKKE ++ + AD++ K
Sbjct: 7507 DKLKQDADAKLQKEKDDKLKQEADAKLKKEKDDKLKHEADAKLKKEKDDKLKQEADAKLK 7566
Query: 698 TAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVE---LRQVHLEKQVNERKMKLAFELS 754
D++ A+A+ E K+ E + ++ K + +Q K E+ KL E
Sbjct: 7567 KEKDDKLKQDADAKLKKEKDDKLKHEADAKLQKEKDDNFKQEANAKLQKEKDDKLKQEKD 7626
Query: 755 KT--KEATKRFEAEKKKLLVE------KINAESKIKKAQE-----RSESELDKKTADMEK 801
+EA + + EK L + K A++K+KK ++ ++++L K+ D K
Sbjct: 7627 DNFKQEANAKLQKEKDDKLKQEKDDKLKQEADAKLKKEKDDKLKQEADAKLKKEKDDKLK 7686
Query: 802 QQAEEQ-KKLAEDKL 815
Q+A+ + KK +DKL
Sbjct: 7687 QEADAKLKKDKDDKL 7701
Score = 125 bits (313), Expect = 7e-27
Identities = 200/811 (24%), Positives = 360/811 (43%), Gaps = 97/811 (11%)
Query: 50 ESENKKLKKDI-----QEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILE 104
+ ++ KLK+D +E+ + K + KL+ L++E A + KK K D L+
Sbjct: 7503 KEKDDKLKQDADAKLQKEKDDKLKQEADAKLKKEKD-DKLKHEADAKL---KKEKDDKLK 7558
Query: 105 EQAQGKIC----DQLK-----KCEKVVEGRNALRQAVKILEKRIENLESE-NKKLKKDI- 153
++A K+ D+LK K +K + + K+ +++ +N + E N KL+K+
Sbjct: 7559 QEADAKLKKEKDDKLKQDADAKLKKEKDDKLKHEADAKLQKEKDDNFKQEANAKLQKEKD 7618
Query: 154 ----QEEQAQRKIEIEGKLEKSNAFAALENEVSALKSEN----KKLKKDILEEQAQRKVA 205
QE+ K E KL+K + + LK E KK K D L+++A K+
Sbjct: 7619 DKLKQEKDDNFKQEANAKLQKEKDDKLKQEKDDKLKQEADAKLKKEKDDKLKQEADAKLK 7678
Query: 206 MEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALR 265
E ++ E + K ++ KLKQ+ D + + + D+LK++ +
Sbjct: 7679 KEKDDKLKQ-----EADAKLKKDKDDKLKQEA-DAKLKKEKDDKLKQEAD---------- 7722
Query: 266 QAVKILEKGIENLESE-NKKLKKDI-----QEEHAQRKVEIEGKL-EISNAFAALENEVS 318
K+ + + L+ E + KLKKD QE A+ K E + KL + N E +
Sbjct: 7723 --AKLKKDKDDKLKQEADAKLKKDKDDKLKQEADAKLKKEKDDKLKQEKNDKLKQEADAK 7780
Query: 319 ALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSEN----KKLKQDIL 374
K ++ KLK+ E A+ K + KL+ +++ LK E KK K D L
Sbjct: 7781 LKKEKDDKLKQ---EADAKLKKEKDDKLKQETDAKLKKDKDDKLKQEADAKLKKDKDDKL 7837
Query: 375 EEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESE-NKKLKKDIQEEQAQRK 433
+++A K K ++ +G+ + K+ ++ L+ E + KLK QE A+ K
Sbjct: 7838 KQEADAKLKKDKDDKLKQEADGKLKKEKDNKLKQEADGKLKKEKDNKLK---QEADAKLK 7894
Query: 434 IEIEGKLEISNAFAALENEVS-ALKSES-TKLKKDI-----LEEQAQIKVAIEEKLEISN 486
E + KL+ A A L+ E LK E+ KLKKD E A++K ++KL+
Sbjct: 7895 KEKDDKLK-QEADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEADAKLKKEKDDKLKQEA 7953
Query: 487 AFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNT-LKKELVEKE 545
+++ LK E A QK + D ++ K ++E + LKKE +K
Sbjct: 7954 DAKLKKDKDDKLKQEANAKLQKEKDDKLKQEADAKLQKEKDDKLKQEADAKLKKEKDDKL 8013
Query: 546 KIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVA 605
K AD++ + D++ K A+A+ E K+ E + K+K +
Sbjct: 8014 KQEADAKLQKEKDDKLKQEADAKLKKEKDDKLKQE-----------ADAKLQKEKDDNFK 8062
Query: 606 VGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEV 665
NA Q EK + + ++ KLK+E + K + L+Q+ A ++ D
Sbjct: 8063 QEANAKLQK----EKDDKLKQEKDDKLKQEADAKLKKEKDDKLKQEADAKLKKDKDDKLK 8118
Query: 666 LKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVE 725
+A K++ ++LK+E AD++ K D++ A+A+ + K+ E +
Sbjct: 8119 QEADAKLKKEKDDKLKQE--------ADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEAD 8170
Query: 726 KQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQ 785
++ K + ++ E +K K +T K+ + +K K + + K K +
Sbjct: 8171 AKLKKDKDDKLKQEADAKLKKEKDDKLKQETDAKLKKDKDDKLKQEADAKLKKEKDDKLK 8230
Query: 786 ERSESELDKKTADMEKQQAEEQ-KKLAEDKL 815
+ ++++L K+ D KQ+A+ + KK +DKL
Sbjct: 8231 QEADAKLKKEKDDKLKQEADAKLKKEKDDKL 8261
Score = 117 bits (294), Expect = 1e-24
Identities = 186/840 (22%), Positives = 357/840 (42%), Gaps = 92/840 (10%)
Query: 19 EELKKKCEQV---VVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKL 75
EELK QV VV + ++ +E+ L+ ++KK KK E + ++A+E
Sbjct: 9053 EELKLDDVQVNNEVVTEITIEESEVTIEEH-RKLKKKSKKSKKTTDEPELDSEIALEVSS 9111
Query: 76 EISNTFAALENEVSALISENKKLKQDILE------EQAQGKICDQL-KKCEKVVEGRNAL 128
+I+++ LE + I + Q+ L E KI + + +K V A+
Sbjct: 9112 DITSS---LEITTESTIPDTAPESQETLNVEIAVTETTVQKITNPSDESAKKDVNEDTAV 9168
Query: 129 RQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSEN 188
VK +K + KK + E K EI+GK EK E S++ +
Sbjct: 9169 SSIVKKDDKDVN---------KKSLPESGLTTKKEIQGKPEKKIMKKKTEKADSSISETS 9219
Query: 189 KKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCD 248
+ L KD+ + + + E S +++EV K KQ + G D
Sbjct: 9220 ETLTKDLTQTKQSEPEPAKRTTETS-----VQDEVKRKTETTSKSKQTTEEHPQPGGKSD 9274
Query: 249 RL---KKKCEKVVEGRNALRQAVKILEKG-IENLESENKKLK--------KDIQEEHAQR 296
+V + + + +A K+ EK LES++K + K+ +E ++
Sbjct: 9275 SSISSTSDASEVKQVQQSESEAQKVTEKPETAKLESKSKMTEDTTKESDNKETVDEKPKK 9334
Query: 297 KVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALE 356
KV ++ K E S++ + +E SA++S E Q V E K + ++ LE
Sbjct: 9335 KV-LKKKTEKSDSTISETSETSAVESAGPSES----ETQNVAAVDKEKKQKETDEKQKLE 9389
Query: 357 NEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKV-VEGRNALRQAVKILEKGIENLE 415
E++ KS +K K + + + D KK+ EK + A + +++ ++ N
Sbjct: 9390 AEIAGKKSTEQKSKLEAEAKLKRAAEEDAAKKQKEKTEAASKKAAAEKLELEKQAQINKA 9449
Query: 416 SENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALE---NEVSALKSESTKLKKDILEEQA 472
+E +KK Q +++ + KLE + AA + E SA KS+ ++ L+ Q
Sbjct: 9450 AEADAVKK-------QNELDEQNKLEATKKLAAEKLKLEEQSAAKSKQAAEEQAKLDAQT 9502
Query: 473 QIKVAIE----EKLEISNAFAALENEVSALKSEIAALQQKC-----GAGSREGNGDVEVL 523
+ K A + EK E SN + NE K + L++K +
Sbjct: 9503 KAKAAEKQTGLEKDEKSNKDSG-SNETVEEKPKKKVLKKKTEKSDSSISQKSDTSKTVAE 9561
Query: 524 KAGISDTEKE----VNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAP 579
AG S++E + + +KE +K+K+ A+ K + DE+ K E+ KL++AA+ A
Sbjct: 9562 SAGSSESETQKVADATSKQKETDKKQKLEAEITAKKSADEKSKLETES-KLIKAAEDAAK 9620
Query: 580 EKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVS 639
++ K E K K E + A + +++ ++ +E +KK+ E++
Sbjct: 9621 KQ-----------KEKEDKLKLEADVASKKAAAEKLELEKQAQIKKAAEADAVKKQKELA 9669
Query: 640 AL-KSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKT 698
K E A +K A + ++ KA E + +KK+ +E+ ++ +K+
Sbjct: 9670 EKQKLESEAATKKAAAEKLKLEEQAQINKAA------EADAVKKQKELDEKNKLEANKKS 9723
Query: 699 AVDERK---NAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSK 755
A ++ K +AA++++ +E K+ A+ +++ A+ + +K + + K +
Sbjct: 9724 AAEKLKLEEESAAKSKQTVEEQAKLDAQTKEKTAEKQTGLEKDDKSTKDSESKETVDEKP 9783
Query: 756 TKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAEDKL 815
K+ K+ + + +K + ++ SESE K KQ+ ++K+ E ++
Sbjct: 9784 KKKVLKKKTEKSDSSISQKSVTSKTVVESGGPSESETQKVADAARKQKETDEKQKLEAEI 9843
Score = 117 bits (293), Expect = 2e-24
Identities = 196/771 (25%), Positives = 352/771 (45%), Gaps = 90/771 (11%)
Query: 43 EKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDI 102
EK + + + KLKKD ++ Q + KL+ + L+ E A + KK K D
Sbjct: 7800 EKDDKLKQETDAKLKKDKDDKLKQEA---DAKLK-KDKDDKLKQEADAKL---KKDKDDK 7852
Query: 103 LEEQAQGKICDQLKKCEKVVEGRNALRQAV--KILEKRIENLESE-NKKLKKDI-----Q 154
L+++A GK LKK E N L+Q K+ +++ L+ E + KLKK+ Q
Sbjct: 7853 LKQEADGK----LKK-----EKDNKLKQEADGKLKKEKDNKLKQEADAKLKKEKDDKLKQ 7903
Query: 155 EEQAQRKIEIEGKLEKSNAFAALENEVSALKSEN----KKLKKDILEEQAQRKVAMEGKL 210
E A+ K E + KL++ +++ LK E KK K D L+++A K+ +
Sbjct: 7904 EADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEADAKLKKEKDDKLKQEADAKLKKDKDD 7963
Query: 211 EISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVV--EGRNALRQAV 268
++ E K ++ KLKQ+ D + Q + D+LK++ + + E + L+Q
Sbjct: 7964 KLKQ-----EANAKLQKEKDDKLKQEA-DAKLQKEKDDKLKQEADAKLKKEKDDKLKQEA 8017
Query: 269 --KILEKGIENLESE-NKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSEN- 324
K+ ++ + L+ E + KLKK E+ + K E + KL+ + + L+ E
Sbjct: 8018 DAKLQKEKDDKLKQEADAKLKK---EKDDKLKQEADAKLQKEKDDNFKQEANAKLQKEKD 8074
Query: 325 ---KKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDI---LEEQA 378
K+ K D L+++A K+ E ++ E + K ++ KLKQ+ L+++
Sbjct: 8075 DKLKQEKDDKLKQEADAKLKKEKDDKLKQ-----EADAKLKKDKDDKLKQEADAKLKKEK 8129
Query: 379 QGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESE-NKKLKKDI-----QEEQAQR 432
K + K +K + + K+ + + L+ E + KLKKD QE A+
Sbjct: 8130 DDKLKQEADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEADAKLKKDKDDKLKQEADAKL 8189
Query: 433 KIEIEGKLEISNAFAALENEVSALKSES-TKLKK---DILEEQAQIKVAIEEKLEISN-A 487
K E + KL+ +++ LK E+ KLKK D L+++A K+ E+ ++ A
Sbjct: 8190 KKEKDDKLKQETDAKLKKDKDDKLKQEADAKLKKEKDDKLKQEADAKLKKEKDDKLKQEA 8249
Query: 488 FAALENEVS-ALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVN-TLKKELVEKE 545
A L+ E LK E A +K + D ++ K ++E + LKKE K
Sbjct: 8250 DAKLKKEKDDKLKQEADAKLKKDKDDKLKQEADAKLKKDKDDKLKQEADGKLKKEKDNKL 8309
Query: 546 KIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVA 605
K AD + K D + K A+A+ E K+ E + K D+LK++ +
Sbjct: 8310 KQEADGKLKKEKDNKLKQEADAKLKKEKDDKLKQEADAKLKK----DKDDKLKQEAD--- 8362
Query: 606 VGRNALRQAVKILEKGIENLESE-NKKLKKENEVSALKSEISALQQKCGAGAREGNGDVE 664
K+ ++ + L+ E + KLKKE + LK E A +K + D +
Sbjct: 8363 ---------AKLKKEKDDKLKQEADAKLKKEKD-DKLKQEADAKLKKDKDDKLKQEADAK 8412
Query: 665 VLKAGISDTKKEVN-RLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAE 723
+ K K+E + +LKKE ++ + AD++ K D++ A+A+ + K+ E
Sbjct: 8413 LKKDKDDKLKQEADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEADAKLKKDKDDKLKQE 8472
Query: 724 VEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEK 774
+ ++ K + ++ LE Q N+ ++ FE + E T + +++ ++V K
Sbjct: 8473 ADAKLKKEKGDKLKLEDQTNQSRI---FE-ETSIEVTSLLKCKQQAIIVSK 8519
Score = 112 bits (279), Expect = 6e-23
Identities = 185/787 (23%), Positives = 341/787 (42%), Gaps = 103/787 (13%)
Query: 83 ALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENL 142
A ++E ++ K+ + ++E + K D+ K E+ +N + V + EK
Sbjct: 12796 AKKSEKKDEVTAEKQSTEALIESKK--KEVDESKISEQQPSDKNK-SEVVGVPEK----- 12847
Query: 143 ESENKKLKKDIQE-EQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEE--- 198
+ + KKD+ E E+ +K I+ K EKS++ + ++ V ++K D+ ++
Sbjct: 12848 -AAGPETKKDVSEIEEVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSKK 12906
Query: 199 --QAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEK 256
+ Q KVA + KLE A + + + ++D++++ K + +K +
Sbjct: 12907 TTEDQTKVATDSKLE------------KAADTTKQIETETVVDDKSKKKVLKKKTEKSDS 12954
Query: 257 VVEGRNALRQAV---KILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAAL 313
+ ++ V K E + + NK K+ +++ +R+ E+ K +I++ +
Sbjct: 12955 FISQKSETPPVVEPTKPAESEAQKIAEVNKAKKQKEVDDNLKREAEVAAK-KIADEKLKI 13013
Query: 314 ENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDI 373
E E + K+ + K E+ Q K LE EV + KS +KL+
Sbjct: 13014 EAEANIKKTAEVEAAKKQKEKDEQLK---------------LETEVVSKKSAAEKLE--- 13055
Query: 374 LEEQAQGKFC---DQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQA 430
LE+QAQ K D +KK +K + +N L A K ++ LE E+ K + EE
Sbjct: 13056 LEKQAQIKKAAEADAVKK--QKELNEKNKLEAAKKSAADKLK-LEEESAAKSKKVSEESV 13112
Query: 431 QRKIEIEGKLEISNAFAALENEVSALKSESTK-LKKDILEEQAQIKVAIEEKLEISNAFA 489
K E K + +E+E ++ K+ TK + ++ K I++K E S++
Sbjct: 13113 --KFGEEKKTKAGEKTVQVESEPTSKKTIDTKDVGATEPADETPKKKIIKKKTEKSDSSI 13170
Query: 490 ALENEVSALKSEIAALQQKCGAGSREGNGDVE-VLKAGISDTEKEVNT---LKKELVEKE 545
+ + SA SE + Q++ ++ + + V +A S +KE + L E+ K
Sbjct: 13171 S---QKSATDSEKVSKQKEQDEPTKPAVSETQMVTEADKSKKQKETDEKLKLDAEIAAKT 13227
Query: 546 KIVADSERKTAVDERKKAAAE---ARKLLE-----------AAKKIAPEKAVIPEPANC- 590
K AD + K E+ K +E ARK E A KK + +K + E A
Sbjct: 13228 KQEADEKSKLDAQEKIKKVSEDDAARKEKELNDKLKLESEIATKKASADKLKLEEQAQAK 13287
Query: 591 -CSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENK-KLKKENEVSALKSEISAL 648
++ + KK+ EK + A K + E LE E + ++KK A+K +
Sbjct: 13288 KAAEVEAAKKQKEKDEQLKLDTEAASK--KAAAEKLELEKQAQIKKAAGADAVKKQKELD 13345
Query: 649 QQ-KCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNAA 707
++ K A + G +++ + + +K+ V K + + A+ + K DE+
Sbjct: 13346 EKNKLEANKKSAAGKLKIEEESAAKSKQTVEEQAKLDAQTKAKTAEKQTKLEKDEKSTKE 13405
Query: 708 AEARKLL-EAPKK--IAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFE 764
+E+++ + E PKK + + EK + + + K V E E K +A ++ +
Sbjct: 13406 SESKETVDEKPKKKVLKKKTEKSDSSISQKS-ETSKTVVESAGPSESETQKVADAARKQK 13464
Query: 765 A--EKKKLLVE-----------KINAESKIKKAQERSESELDKKTADMEKQQAE-EQKKL 810
EK+KL E K+ AESK+KKA E ++ K+ + K E KK
Sbjct: 13465 ETDEKQKLEAEITAKKSADEKSKLEAESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKA 13524
Query: 811 AEDKLLL 817
A +KL L
Sbjct: 13525 AAEKLEL 13531
Score = 92.8 bits (229), Expect = 4e-17
Identities = 149/604 (24%), Positives = 285/604 (46%), Gaps = 76/604 (12%)
Query: 12 ANCCSKCEEL--KKKCEQVVVGRNALRQAVKILEKGIEN--LESENKKLKKDIQEE---Q 64
A+ K +EL K+K E + A + +K+ E+ N E++ K +K++ E+ +
Sbjct: 9659 ADAVKKQKELAEKQKLESEAATKKAAAEKLKLEEQAQINKAAEADAVKKQKELDEKNKLE 9718
Query: 65 AQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKI-CDQLKKCEKVVE 123
A +K A E KL++ AA + + E KL E+ A+ + ++ K K E
Sbjct: 9719 ANKKSAAE-KLKLEEESAAKSKQT---VEEQAKLDAQTKEKTAEKQTGLEKDDKSTKDSE 9774
Query: 124 GRNAL--RQAVKILEKRIENLES---ENKKLKKDI------QEEQAQRKIEIEGKLEKSN 172
+ + + K+L+K+ E +S + K + E + Q+ + K ++++
Sbjct: 9775 SKETVDEKPKKKVLKKKTEKSDSSISQKSVTSKTVVESGGPSESETQKVADAARKQKETD 9834
Query: 173 AFAALENEVSALKSENKKLKKDILEEQAQRKVAME----GKLEISNAFAALENEVSALKS 228
LE E++A KS ++K K LE +++ K A E K + + L+ E ++ K+
Sbjct: 9835 EKQKLEAEITAKKSADEKSK---LEAESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKA 9891
Query: 229 ENKKLKQDILDEQAQGKFC---DRLKK--------KCEKVVEGRNALRQAVKILEKGIEN 277
+KL+ L++QAQ K D +KK K E + A + +K+ E+ ++
Sbjct: 9892 AAEKLE---LEKQAQIKKAAEADAVKKEKELAEKQKLESEAATKKAAAEKLKLEEQKKKD 9948
Query: 278 LESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQ 337
E+ + + +K+ QE+ AQ + ++E + S LE+E + K+E + K+ ++E+ +
Sbjct: 9949 AETASIEKQKE-QEKLAQEQSKLEVDAKKSAEKQKLESETKSKKTE--EAPKESVDEKPK 10005
Query: 338 RKVAMEGKLEISNAFAALENEV------SALKSENKKLKQDILEEQAQGKFCDQLKKKCE 391
+KV ++ K E S++ + +++ SA +S+++ K ++ + K D+ K+K E
Sbjct: 10006 KKV-LKKKTEKSDSSISQKSDTAKTVAESAGQSDSETQKVSEADKAHKQKESDE-KQKLE 10063
Query: 392 KVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALEN 451
+ + + Q K LE+E K KK I++E A+++ E E K + ++ ++
Sbjct: 10064 SEIAAKKSAEQKSK--------LETE-AKTKKVIEDESAKKQKEQEDKKKGDDSAKKQKD 10114
Query: 452 EVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGA 511
+ K ES K E+ + + +EK A ENE + + +E L+ K
Sbjct: 10115 QKEKQKLESEATSKKPTSEKQKDEKTPQEK-------AKSENE-TVMTTEPQQLEVKSEP 10166
Query: 512 GSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKK--AAAEARK 569
+ VE K S TEK ++ KE EK+KI+ + T E K ++ E+R
Sbjct: 10167 KKSDKTETVE--KEVASSTEKSDDSKTKEPKEKKKIIKKKKDTTKPQEASKELSSDESRI 10224
Query: 570 LLEA 573
LE+
Sbjct: 10225 DLES 10228
Score = 76.3 bits (186), Expect = 4e-12
Identities = 99/462 (21%), Positives = 199/462 (42%), Gaps = 47/462 (10%)
Query: 396 GRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSA 455
G A + +++ + ES + +++++ + Q E+ ++ I + +E E
Sbjct: 9026 GEGAPSEIIEVNTLDYDQEESFDFAGEEELKLDDVQVNNEVVTEITIEESEVTIE-EHRK 9084
Query: 456 LKSESTKLKKDILEEQAQIKVAIEEKLEISNAFA----------------ALENEVSALK 499
LK +S K KK E + ++A+E +I+++ L E++ +
Sbjct: 9085 LKKKSKKSKKTTDEPELDSEIALEVSSDITSSLEITTESTIPDTAPESQETLNVEIAVTE 9144
Query: 500 SEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVE-----KEKIVADSERK 554
+ + + +++ + + + + +K+VN KK L E K++I E+K
Sbjct: 9145 TTVQKITNPSDESAKKDVNEDTAVSSIVKKDDKDVN--KKSLPESGLTTKKEIQGKPEKK 9202
Query: 555 TAVDERKKAAAEARKLLEA-AKKIAPEKAVIPEPANCCSKC---DELKKKCEKVAVGRNA 610
+ +KA + + E K + K PEPA ++ DE+K+K E + +
Sbjct: 9203 IMKKKTEKADSSISETSETLTKDLTQTKQSEPEPAKRTTETSVQDEVKRKTETTSKSKQT 9262
Query: 611 LRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGI 670
+ + K ++ S + + +V +SE + +K E +
Sbjct: 9263 TEEHPQPGGKSDSSISSTSDA-SEVKQVQQSESEAQKVTEKPETAKLESKSKMTEDTTKE 9321
Query: 671 SDTKKEVNR------LKKEHVEEERIVADSERKTAVDERKNAAAEARKL--LEAPKKIAA 722
SD K+ V+ LKK+ + + ++++ +AV+ + +E + + ++ KK
Sbjct: 9322 SDNKETVDEKPKKKVLKKKTEKSDSTISETSETSAVESAGPSESETQNVAAVDKEKKQKE 9381
Query: 723 EVEKQIAKVELRQVHLEKQVN----ERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAE 778
EKQ + E+ +Q + E K+K A E K+ ++ EA KK EK+ E
Sbjct: 9382 TDEKQKLEAEIAGKKSTEQKSKLEAEAKLKRAAEEDAAKKQKEKTEAASKKAAAEKLELE 9441
Query: 779 SKIKKAQERSESELD--KKTADMEKQ-QAEEQKKLAEDKLLL 817
K+AQ +E D KK ++++Q + E KKLA +KL L
Sbjct: 9442 ---KQAQINKAAEADAVKKQNELDEQNKLEATKKLAAEKLKL 9480
Score = 75.5 bits (184), Expect = 7e-12
Identities = 169/816 (20%), Positives = 318/816 (38%), Gaps = 109/816 (13%)
Query: 32 RNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLE--ISNTFAALENEVS 89
R L++ +++E ++ + KK KK + +R+ +L I F + ++
Sbjct: 12391 RRRLQRGRRVMEASSDSELDDAKKRKKRRIKRVVERRNPNAPRLTQLIPPRFDKILSDHD 12450
Query: 90 ALISENKKLKQDILEEQA-------QGKICDQLKKCEKVVEGRNALRQAVKILEKRIENL 142
A+ EN + + L E GK+ D V + +R+ IL
Sbjct: 12451 AIEGENVVMMVETLGEPEPQVRFYRDGKLIDDGSGDRMEVRHEDEMRKHWLIL------- 12503
Query: 143 ESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQR 202
K + KD + E A + I + G+ A ++V SE + ++E
Sbjct: 12504 ----KDICKDEEAEYACQAINVAGE-------AWCFSDVVVHMSEESRDDDKSVDEVDDS 12552
Query: 203 KVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRN 262
V E K + ++ S K++ K +K+ E Q + ++K +V + ++
Sbjct: 12553 TVLEEKKDD--------GDDKSKPKTKKKIIKKKETPESEQVTAAEPEQQKISEV-DVQS 12603
Query: 263 ALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKVEIEGKLEISNAFAALENEVSALKS 322
V +K ++ K KKD + + + E E E + N+ ++ KS
Sbjct: 12604 VAETEVGAKKKPDAEKPTDLSKAKKDSKSKKSD---EPEASTEEKSTTEKPTNDKTSKKS 12660
Query: 323 ENKKL---KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQD----ILE 375
KK KK++ + + K +E K + S ++ E S+ ++ KK KQ +
Sbjct: 12661 AEKKTVKPKKEVTGKPLEAKKPVEDKKDASQPSSSKE---SSPPTDGKKKKQIPKALFIP 12717
Query: 376 EQAQGKFCDQLKKKCEK----VVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQ 431
++ +F D E + GR A L +E L + ++ E A+
Sbjct: 12718 DEISSRFGDPSTMHSETNITTTIRGREGSADAKTPL---VEPLSAS-----VSMKVESAK 12769
Query: 432 RKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIE-EKLEISNAFAA 490
K E K + ++ ++ K ++ E+ + IE +K E+ + +
Sbjct: 12770 EKAEFSFKRRSETPDDKSRKKEGLPPAKKSEKKDEVTAEKQSTEALIESKKKEVDESKIS 12829
Query: 491 LENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVAD 550
+ KSE+ + +K A E DV + I + K+ T+KK+ + + ++
Sbjct: 12830 EQQPSDKNKSEVVGVPEK--AAGPETKKDV----SEIEEVPKK-KTIKKKTEKSDSSISQ 12882
Query: 551 SER--KTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGR 608
K A D++ K+ + + +KK ++ + + D K+ + V
Sbjct: 12883 KSNVLKPADDDKSKSD----DVTDKSKKTTEDQTKVATDSKLEKAADTTKQIETETVVDD 12938
Query: 609 NALRQAVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKA 668
+ ++ +K KK +K + + KSE + + E EV KA
Sbjct: 12939 KSKKKVLK-------------KKTEKSDSFISQKSETPPVVEPTKPAESEAQKIAEVNKA 12985
Query: 669 GISDTKKEVN-RLKKEHVEEERIVADSERKTAVDERKNAAAE---ARKLLEAPKKIAAEV 724
+KEV+ LK+E + +AD + K + AE A+K E +++ E
Sbjct: 12986 ---KKQKEVDDNLKREAEVAAKKIADEKLKIEAEANIKKTAEVEAAKKQKEKDEQLKLET 13042
Query: 725 EKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKA 784
E K ++ LEKQ +K A + K KE EK KL K +A K+K
Sbjct: 13043 EVVSKKSAAEKLELEKQAQIKKAAEADAVKKQKELN-----EKNKLEAAKKSAADKLK-- 13095
Query: 785 QERSESELDKKTADMEKQQAEEQKKLAEDKLLLLGD 820
L++++A K+ +EE K E+K G+
Sbjct: 13096 -------LEEESAAKSKKVSEESVKFGEEKKTKAGE 13124
Score = 68.9 bits (167), Expect = 6e-10
Identities = 152/786 (19%), Positives = 315/786 (39%), Gaps = 108/786 (13%)
Query: 93 SENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKD 152
S+ KK ++ L Q K LKK + E A ++ ++ +++ NK +KK
Sbjct: 10740 SKTKKQEKSALSVQEMNK---SLKKKGEKGEAETAASDFIENADQTGMSIQDLNKSMKKK 10796
Query: 153 IQEEQAQRKIEIEGKLEKSNAFAALENEVS-ALKSENKKLKKDILEEQAQRKVAMEGKLE 211
++ +A +I + ++ + +++ S KSEN+ + + L++ + + K+
Sbjct: 10797 VESGEATGQINDASNNKDADELSIQDSQQSLKKKSENESVTGEQLDKSQE---VEDDKMT 10853
Query: 212 ISNAFAALE-----NEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEK--VVEGRNAL 264
I + +++ EVS KSE K K+ DE + + +KKK E V +G++
Sbjct: 10854 IQSLKKSIKKKPESREVSGGKSEKSKEKES--DEMSIQQLNKSVKKKPENEAVTQGKSGK 10911
Query: 265 RQ-------AVKILEK------GIENLE-------SENKKLKKDIQEEHAQRKVEIEGKL 304
Q +++ L K G++ +E S+ +L + + ++E
Sbjct: 10912 SQEQESDKMSIQALNKSMKKKDGVDGVEGNINIGRSDGDQLSVNDIDAELSTSEQVENAS 10971
Query: 305 EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKS 364
+ A A + + +L++ K++ K + +A+ K+ G+ + + L++ LK+
Sbjct: 10972 QNLGATADSDGDSLSLQTLKKRISKKGIHGEAESKL---GEKQSGSDSFTLQDLYEELKA 11028
Query: 365 ENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKG-IENL--ESENKKL 421
K+D +E A+ DQ +K +E R+ ++ K G ENL ES +
Sbjct: 11029 -----KEDAVEAGAETSNADQSAEKTS--LEVRDMKKKMKKKQVSGTAENLIGESNRDET 11081
Query: 422 KKDIQEEQAQRKIEIEGKLEISNAFAALENE--VSALKSESTKLKKDILEEQAQ---IKV 476
+I++ Q + + F + E +K S KL + EE I
Sbjct: 11082 SMEIRDLNTQHSNQTGEDESSTFNFGQKDQEQYSMVMKDVSKKLARQNAEEIQSGKLIPT 11141
Query: 477 AIEEKLEIS------NAFAALENEVSALK-------SEIAALQQKCGAGSREGNGDVEVL 523
EEK ++ N ENE + + S +L + + G+VE
Sbjct: 11142 TNEEKTGLALTGKNKNLKKGEENEKTKFEAKHLGSSSASDSLAESTLRSKKTKKGEVEKS 11201
Query: 524 KAGISDTEKEVNTLKKELV-------------EKEKIVA--DSERKTAVDERKKAAAEAR 568
+ I ++ TL L+ E E +VA + E+ + RK+ + ++
Sbjct: 11202 ELSIDMKNQDKTTLATTLLEDDLAKTTSAEESEAEHLVALQNKEKTSLAMRRKRVSFDSS 11261
Query: 569 KLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESE 628
E+ + + P+K + + ++ +K E +N + K I + E +
Sbjct: 11262 TKSESIEDVIPDKNRDSDKMSITGIKKKMSQKSESAEAQKNESPEV-----KEISSFEEK 11316
Query: 629 NKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEE 688
K KK+ S + G A G+ ++ ++D + + + + E+
Sbjct: 11317 TLKSKKK----------SKADRNQGTEANLGDKTIDKDYLSVTDKNQSLEKSEASGQAEK 11366
Query: 689 RIVADSERKTAVDERKNAAAEARKLLEAPKKIA----AEVEK--QIAKVELRQVHLEKQV 742
I A ++ K + L A +++A AE EK + V + L K
Sbjct: 11367 SIKAPNKSKVTTSFADESLTSELDRLMADEEMAEMMFAEEEKAADLLNVMNKNKGLNKSE 11426
Query: 743 NERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAE-----SKIKKAQERSESELDKKTA 797
E +++ + + + + KK+ ++K + + SKI ++++ ++KT+
Sbjct: 11427 QEESQEISLKSQSKVKDSDSLSSTDKKIGLKKSDKDQKLGTSKIFGSKDQESVGYEEKTS 11486
Query: 798 DMEKQQ 803
+ KQ+
Sbjct: 11487 NFSKQR 11492
Score = 62.4 bits (150), Expect = 6e-08
Identities = 172/878 (19%), Positives = 331/878 (37%), Gaps = 144/878 (16%)
Query: 34 ALRQAVKILEKGIEN-LESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALI 92
+++Q K ++K EN ++ K K QE A+ ++ + +E ++
Sbjct: 10887 SIQQLNKSVKKKPENEAVTQGKSGKSQEQESDKMSIQALNKSMKKKDGVDGVEGNINIGR 10946
Query: 93 SENKKLK-QDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENL----ESENK 147
S+ +L DI E + + + + + +++ L+KRI E+E+K
Sbjct: 10947 SDGDQLSVNDIDAELSTSEQVENASQNLGATADSDGDSLSLQTLKKRISKKGIHGEAESK 11006
Query: 148 KLKK----------DIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILE 197
+K D+ EE ++ +E E SNA + E ++ KK+KK +
Sbjct: 11007 LGEKQSGSDSFTLQDLYEELKAKEDAVEAGAETSNADQSAEKTSLEVRDMKKKMKKKQVS 11066
Query: 198 EQAQRKVAMEGKLEISNAFAALENEVS-----------------------ALKSENKKLK 234
A+ + + E S L + S +K +KKL
Sbjct: 11067 GTAENLIGESNRDETSMEIRDLNTQHSNQTGEDESSTFNFGQKDQEQYSMVMKDVSKKLA 11126
Query: 235 QDILDEQAQGKFCDRL-KKKCEKVVEGRNALRQAVKILEKGIENLESE-------NKKLK 286
+ +E GK ++K + G+N K L+KG EN +++ +
Sbjct: 11127 RQNAEEIQSGKLIPTTNEEKTGLALTGKN------KNLKKGEENEKTKFEAKHLGSSSAS 11180
Query: 287 KDIQEEHAQRKVEIEGKLEISNAFAALENE-----VSALKSENKKLKKDILEEQAQRKVA 341
+ E + K +G++E S ++N+ + L ++ E +A+ VA
Sbjct: 11181 DSLAESTLRSKKTKKGEVEKSELSIDMKNQDKTTLATTLLEDDLAKTTSAEESEAEHLVA 11240
Query: 342 MEGKLEISNAFAALENEV-SALKSEN---------------------KKLKQDILEEQAQ 379
++ K + S A S+ KSE+ KK+ Q +AQ
Sbjct: 11241 LQNKEKTSLAMRRKRVSFDSSTKSESIEDVIPDKNRDSDKMSITGIKKKMSQKSESAEAQ 11300
Query: 380 ----------GKFCDQLKKKCEKVVEGRNALRQA---VKILEKGIENLESENKKLKKDIQ 426
F ++ K +K RN +A K ++K ++ +N+ L+K
Sbjct: 11301 KNESPEVKEISSFEEKTLKSKKKSKADRNQGTEANLGDKTIDKDYLSVTDKNQSLEKSEA 11360
Query: 427 EEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEK----L 482
QA++ I+ K +++ +FA +L SE +L D EE A++ A EEK L
Sbjct: 11361 SGQAEKSIKAPNKSKVTTSFAD-----ESLTSELDRLMAD--EEMAEMMFAEEEKAADLL 11413
Query: 483 EISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELV 542
+ N L EI+ Q S+ + D +S T+K++ K +
Sbjct: 11414 NVMNKNKGLNKSEQEESQEISLKSQ-----SKVKDSD------SLSSTDKKIGLKKSDKD 11462
Query: 543 EK---EKIVADSERKTAVDERKKA--AAEARKLLEAAKKIAPEKAVIPEPANCCSKCDEL 597
+K KI ++++ E K + + + R + + ++ + E S+ E+
Sbjct: 11463 QKLGTSKIFGSKDQESVGYEEKTSNFSKQRRGVSDLGSDAMTDQKNVQE-----SQYAEI 11517
Query: 598 KKKCEKVAVGRNALRQAVKILEKGIENLE-SENKKLKKENEVSALKSEISALQQKCGAGA 656
G + A + + G + + SE ++ K+ + + A C +
Sbjct: 11518 SADDHMSKTGADGEISATRTIVDGSDAAQGSEYAEISKKRKFKRAEQIGEAETSLC--DS 11575
Query: 657 REGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDE--------RKNAAA 708
RE D ISD E+ R E +I +E T++ + +K
Sbjct: 11576 RENTHD----SLSISDVNPELRRSNVEISAFGQIDLTAEEVTSLTDINKDAQLTKKQDEN 11631
Query: 709 EARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKK 768
+A+K + K A+ + + ++ K+ + R+ E ++ TK + +
Sbjct: 11632 DAKKSVSKNLKAGAKKDSDTLSITSKKDKFGKRQDSREASATVEQQGEEKVTKNLKGSRG 11691
Query: 769 KLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEE 806
K EK+ ++ I E E E T D+E +E+
Sbjct: 11692 K--KEKL-GDAGIDVNFENQE-EFASTTGDIESIVSEK 11725
Score = 60.5 bits (145), Expect = 2e-07
Identities = 157/726 (21%), Positives = 296/726 (40%), Gaps = 101/726 (13%)
Query: 3 SEKAVIPEPANCCSKCEELKKKCEQVVVGRNALRQAV---KILEKGIENLESENKKLKKD 59
++K PE S E+ K ++ RN +A K ++K ++ +N+ L+K
Sbjct: 11299 AQKNESPEVKEISSFEEKTLKSKKKSKADRNQGTEANLGDKTIDKDYLSVTDKNQSLEKS 11358
Query: 60 IQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE 119
QA++ + K +++ +FA +L SE +L D EE A+ ++ K +
Sbjct: 11359 EASGQAEKSIKAPNKSKVTTSFAD-----ESLTSELDRLMAD--EEMAEMMFAEEEKAAD 11411
Query: 120 KVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALEN 179
+ N+ ++NK L K QEE + ++ + K++ S++ ++ +
Sbjct: 11412 LL-------------------NVMNKNKGLNKSEQEESQEISLKSQSKVKDSDSLSSTDK 11452
Query: 180 EVSALKSE-NKKL-KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDI 237
++ KS+ ++KL I + Q V E K ++ F+ VS L S+ ++++
Sbjct: 11453 KIGLKKSDKDQKLGTSKIFGSKDQESVGYEEK---TSNFSKQRRGVSDLGSDAMTDQKNV 11509
Query: 238 LDEQ-AQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLE-SENKKLKKDIQEEHAQ 295
+ Q A+ D + K G + A + + G + + SE ++ K + + A+
Sbjct: 11510 QESQYAEISADDHMSK------TGADGEISATRTIVDGSDAAQGSEYAEISKKRKFKRAE 11563
Query: 296 RKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGK----LEISNA 351
+ E E L S ++ ++ N +L++ +E A ++ + + L N
Sbjct: 11564 QIGEAETSLCDSRENT---HDSLSISDVNPELRRSNVEISAFGQIDLTAEEVTSLTDINK 11620
Query: 352 FAAL---ENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEG-RNALRQAVKIL 407
A L ++E A KS +K LK ++ D L +K G R R+A +
Sbjct: 11621 DAQLTKKQDENDAKKSVSKNLKAGAKKDS------DTLSITSKKDKFGKRQDSREASATV 11674
Query: 408 EKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSE------ST 461
E+ E ++N K + +E+ I++ E FA+ ++ ++ SE S
Sbjct: 11675 EQQGEEKVTKNLKGSRGKKEKLGDAGIDV--NFENQEEFASTTGDIESIVSEKGHDTYSE 11732
Query: 462 KLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVE 521
K K ++ Q A E NA +AL + A L+ + G E +
Sbjct: 11733 KTVKSSKKKSPQTAGAEYGGSESLNASSAL-----STTDVDAQLKNQEKDGVAESSIGKS 11787
Query: 522 VLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEK 581
K S+ E VN KK+ V K + D A+ E+ ++A + A
Sbjct: 11788 NQKDSYSEQELNVNKKKKQAVGAAMNQGSGSTKES-DNLAVASVESNLAKDSANQEASLH 11846
Query: 582 AVIPEPANCCSKCD---ELKKKCEKVA----VGRN------ALRQAVKILEKGIENLESE 628
++ A S+ D LKK+ ++++ +G++ AL + L KG ++ ES
Sbjct: 11847 GLVDNDATSLSQLDSEHRLKKRDDELSAHTKLGKHTQSENIALTETDDSLVKG-DSEESA 11905
Query: 629 NKKLKKENEV-----------SALKSEISALQQKCGAGAREGNGD---VEVLKAGISDTK 674
+K++ E + LK + Q A +G D + V +GIS K
Sbjct: 11906 ELNIKQQGETAEDKYVESRKKTTLKKKPEQKQVTDTLSAVDGRHDTTSLSVADSGISFDK 11965
Query: 675 KEVNRL 680
N L
Sbjct: 11966 SMENEL 11971
Score = 45.8 bits (107), Expect = 0.006
Identities = 81/358 (22%), Positives = 140/358 (38%), Gaps = 69/358 (19%)
Query: 521 EVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKK---- 576
+++K + ++V + E + ++ S +T V +KK AE L AKK
Sbjct: 12573 KIIKKKETPESEQVTAAEPEQQKISEVDVQSVAETEVGAKKKPDAEKPTDLSKAKKDSKS 12632
Query: 577 --------IAPEKAVIPEPAN--CCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLE 626
EK+ +P N K E K K V L + +K +
Sbjct: 12633 KKSDEPEASTEEKSTTEKPTNDKTSKKSAEKKTVKPKKEVTGKPLEAKKPVEDKKDASQP 12692
Query: 627 SENK--------KLKKE--------NEVSALKSEISALQQKCG----AGAREGNGD---- 662
S +K K KK+ +E+S+ + S + + REG+ D
Sbjct: 12693 SSSKESSPPTDGKKKKQIPKALFIPDEISSRFGDPSTMHSETNITTTIRGREGSADAKTP 12752
Query: 663 -VEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDE--RKNAAAEARKLLEAPKK 719
VE L A +S +K E +E+ + R D+ RK K E +
Sbjct: 12753 LVEPLSASVS--------MKVESAKEKAEFSFKRRSETPDDKSRKKEGLPPAKKSEKKDE 12804
Query: 720 IAAEVEKQIAKVELRQVHLEKQVNERKM-------KLAFELSKTKEATKRFEAEKKKLLV 772
+ AE + A +E + +K+V+E K+ K E+ E E +K +
Sbjct: 12805 VTAEKQSTEALIESK----KKEVDESKISEQQPSDKNKSEVVGVPEKAAGPETKKDVSEI 12860
Query: 773 EKINAESKIKKAQERSESELDKKT-----ADMEKQQAEE----QKKLAEDKLLLLGDS 821
E++ + IKK E+S+S + +K+ AD +K ++++ KK ED+ + DS
Sbjct: 12861 EEVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSKSDDVTDKSKKTTEDQTKVATDS 12918
Score = 40.4 bits (93), Expect = 0.24
Identities = 95/408 (23%), Positives = 169/408 (41%), Gaps = 85/408 (20%)
Query: 337 QRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEG 396
++KV LEI+N ++ K K L E G++ Q+ V
Sbjct: 14969 RKKVGDSDWLEIAN-------------TDRNKFKDRSLTES--GEYVYQVTATGIHAVSS 15013
Query: 397 RNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKI--EIEGKLEISNAFAALENEVS 454
+ VKIL G E S+ +K K D + ++++K EI + ++ + A+ E+
Sbjct: 15014 PSEETNPVKILVPGSEMPASKTEK-KTDAAKSESEQKSAEEIVAEKQVDQSQAS-ESTTE 15071
Query: 455 ALKSESTK--LKKDILEEQAQIKVA-IEEKLEISNAFAALENEVSALKSEIAALQQKCGA 511
A++ + TK +KK + E + + + ++EKL+ A +++E
Sbjct: 15072 AVEEKKTKKVVKKKVAENKGEETLQEVKEKLKKGKAVEKVQDE----------------- 15114
Query: 512 GSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLL 571
SR G+ L+A SD E T +K + ++ +SE+ E+K +A+ L
Sbjct: 15115 -SRRGS-----LQAS-SDNESVTTTSEKR--SEAELEKNSEKSA---EKKSTSAD----L 15158
Query: 572 EAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKK 631
EAA K EK+ + ++ KK +KVA +KG+ + +
Sbjct: 15159 EAADKAETEKSETGKETT-----EKKKKVVKKVA-------------KKGLVKADKSKIE 15200
Query: 632 LK--KENEVSALKSEIS-ALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEE 688
L KE E+SA +E +++ K A + + V G+S K + V
Sbjct: 15201 LTAGKEGEISAQVAETGVSVEWKKDGKALDASYTV-TSTGGVSTVKIPI-----VDVNTS 15254
Query: 689 RIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQV 736
+ + + DE + + A KL E PK E E+ I +V++ V
Sbjct: 15255 GVFTCKVKSSEGDEEEVSIAVTVKLPEVPK---VEAEQSIVEVKVGDV 15299
Score = 40.0 bits (92), Expect = 0.31
Identities = 136/735 (18%), Positives = 264/735 (35%), Gaps = 104/735 (14%)
Query: 130 QAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEK-----------------SN 172
Q +I+E++ E E K+L +++ E + E+ LE S
Sbjct: 4693 QPAEIVEQKDVTCEEEIKELLTEVEVELFFSQAEVFSGLELDLLMECSEYVTTSIQKGST 4752
Query: 173 AFAALENEVSALKS-ENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENK 231
A A E V L E+K+ + E ++K + + +E E
Sbjct: 4753 AAPAQEPTVEKLAPVESKETSEVEPAEIVEQKDVPVPETSAPSVEPTVEKLAPVESKETS 4812
Query: 232 KLKQDILDEQAQGKFCDRLKKKCEKVVEG-------RNALRQAVKILEKGIENLESENKK 284
+++Q + EQ + E VE + Q +I+E+ E E K+
Sbjct: 4813 EVQQAEIVEQKDVPVPETSAPSVEPTVEKLAPAESKETSEVQPAEIVEQKDVTCEEEIKE 4872
Query: 285 LKKDIQEEHAQRKVEIEGKLEISNAF-------AALENEVSALKSENKKLKKDILEEQAQ 337
L +++ E + E+ LE+ +++ +A ++ ++K E +
Sbjct: 4873 LLTEVEVELFFSQAEVFSGLELDLLMECSEYVTTSIQKGSTAAPAQEPTVEKLAPVESKE 4932
Query: 338 RKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGR 397
+ ++ E ++ +KLK +E ++ + + +++K V E
Sbjct: 4933 TSEVQQAEIIEQKDVPVPETSAPTVEPTVEKLKPVESKETSEVQQVEIIEQKDVPVPE-- 4990
Query: 398 NALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALK 457
+ +E +E L K ++Q+ + IE + + +E V LK
Sbjct: 4991 ----TSAPTVEPTVEKLAPVESKETSEVQQAEI---IEQKDVPVPETSAPTVEPTVEKLK 5043
Query: 458 SESTKLKKDILE----EQAQIKV------AIEEKLEISNAFAALENEVSALKSEIAALQQ 507
+K ++ + EQ + V +E +E A +E++ ++ + ++Q
Sbjct: 5044 PVESKETSEVQQVEIIEQKDVPVPETSAPTVEPTVE---KLAPVESKETSEVQQAEIIEQ 5100
Query: 508 KCGAGSREGNGDVEVLKAGISDTEKEVNTLK----KELVEKEKIVADSERKTAVDE---- 559
K DV V + E V LK KE E +++ ++ V E
Sbjct: 5101 K----------DVPVPETSAPTVEPTVEKLKPVESKETSEVQQVEIIEQKDVPVPETSAP 5150
Query: 560 ------RKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQ 613
K A E+++ E E+ V+P P + +K V Q
Sbjct: 5151 TVEPTVEKHAPVESKETSEVQPAEIVEQKVVPVPETSAPTVEPTVEKLAPVESKETPEVQ 5210
Query: 614 AVKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDT 673
+ILE+ E E K+L E EV S+ EV D
Sbjct: 5211 PAEILEQKDVTCEEEIKELLTEVEVELFFSK------------------AEVFSGLELDL 5252
Query: 674 KKEVNRLKKEHVEEERIVADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVEL 733
E + +++ A ++ T K A E+++ E E +K + E
Sbjct: 5253 LMECSEYVTTSIQKGSTAAPAQEPTV---EKLAPVESKETSEVEPAEIVE-QKDVPVPET 5308
Query: 734 RQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELD 793
+E V + K + E +T E + E+K + V + +A + ++ E+
Sbjct: 5309 SAPTVEPTVEKLK---SVESKETSEVQQAEIIEQKDVPVPETSAPT-VEPTVEKLAPVDS 5364
Query: 794 KKTADMEKQQAEEQK 808
K+T+++E + EQK
Sbjct: 5365 KETSEVEPAEIVEQK 5379
Score = 38.9 bits (89), Expect = 0.69
Identities = 82/334 (24%), Positives = 145/334 (42%), Gaps = 40/334 (11%)
Query: 33 NALRQAV--KILEKGIENLESE-NKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVS 89
N L+Q K+ ++ + L+ E + KLKKD ++++ +++ + K E + L+ E
Sbjct: 8323 NKLKQEADAKLKKEKDDKLKQEADAKLKKD-KDDKLKQEADAKLKKEKDDK---LKQEAD 8378
Query: 90 ALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESE-NKK 148
A + KK K D L+++A K+ + K +K+ + +A K+ + + + L+ E + K
Sbjct: 8379 AKL---KKEKDDKLKQEADAKL--KKDKDDKLKQEADA-----KLKKDKDDKLKQEADAK 8428
Query: 149 LKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEG 208
LKK E+ + K E + KL+K L+ E A + KK K D L+++A K+ E
Sbjct: 8429 LKK---EKDDKLKQEADAKLKKDKD-DKLKQEADA---KLKKDKDDKLKQEADAKLKKEK 8481
Query: 209 ----KLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGR--- 261
KLE + + E S + K KQ + C+R+ E+
Sbjct: 8482 GDKLKLEDQTNQSRIFEETSIEVTSLLKCKQQAIIVSKSFALCERVVLNAEEPFTLEVFC 8541
Query: 262 NALRQAVKILEKGIENLESENKKLKKDIQEEHAQR------KVEIEGKLEISNAFAALEN 315
NA+ + + GI + + KKD E R ++ L I + +
Sbjct: 8542 NAVFVKQRTDKIGIGIIFERSGASKKD--ESRPDRLDDNCVLTDVTDGLSILSPPPKAKK 8599
Query: 316 EVSALKSENKKLKKDILEEQAQRKVAMEGKLEIS 349
+ K +KK K + E + K K EIS
Sbjct: 8600 HLKKKKKHHKKEKIAVKETEQDEKTVSHLKPEIS 8633
Score = 37.7 bits (86), Expect = 1.5
Identities = 52/273 (19%), Positives = 124/273 (45%), Gaps = 26/273 (9%)
Query: 294 AQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFA 353
A+ K E+E + + E+ + KK+I+ ++ Q+ +++ +++++
Sbjct: 1967 AKAKGEVENLKKCVETLLLFDAEMDMKDIKESSPKKEIISKKDQQ--SLDDQIKVTQQIL 2024
Query: 354 A-LENEVSALK--------SENKKL--KQDILE-EQAQGKFCDQLKKKCEKVVEGRNALR 401
+E +++ ++ S NK+ +D+ + E A DQL + R AL+
Sbjct: 2025 KDVERDLNKMERTSPGKSLSPNKRTFAPKDVEDIEAAIFSISDQLADRQSSEEALREALQ 2084
Query: 402 QAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKL-------EISNAFAALENEVS 454
+ + ++ L N+ K ++ + + Q+ E+E K+ ++ A +A+EN +
Sbjct: 2085 EMILSNSSPMKELSRNNETSKPEVLKSEIQKIPEVETKISEVYPIVKLKQAISAIENSLL 2144
Query: 455 ALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKC---GA 511
+E T++ K ++ + K +++ +++ A + S L+ + L Q +
Sbjct: 2145 E-DTEVTEIMKRKGSDKDKRKATRIKRVPSAHS-ARITPITSNLRDRLNQLHQLTVSEDS 2202
Query: 512 GSREGNGDVEVLKAGISDTEKEVNTLKKELVEK 544
GS + N + + ++ EKE+NT+ + EK
Sbjct: 2203 GSLKQNEEAKEIQELFVKIEKEINTIAELCKEK 2235
Score = 37.4 bits (85), Expect = 2.0
Identities = 59/301 (19%), Positives = 123/301 (40%), Gaps = 21/301 (6%)
Query: 529 DTEKEVNTLKKELVEKEKIVADSERKTAVDERKK--AAAEARKLLEAAKKIAPEKAVIPE 586
D+++ E+VE++ + T V+ K+ A E+++ E + E+ +
Sbjct: 6699 DSKETSEVQTAEIVEQKDVPVPETSATTVEPTKEKLAPGESKETSEVQQAAIVEQKDVAV 6758
Query: 587 PANCCSKCDELKKKCEKVAVGRNALRQAVKILEK--------GIENLESENKKLKK-ENE 637
P + + K+K V + Q +I+E+ +E +KL E++
Sbjct: 6759 PETSATTVEPTKEKLAPVESKETSEIQTAEIVEQKDVPVPETSTSYVEPTKEKLAPGESK 6818
Query: 638 VSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTK-KEVNRLKKEHVEEERIVADSER 696
++ + + ++QK VE K ++ + KE + +++ V E++ V E
Sbjct: 6819 ETSEVQQAAIVEQKDVPVPETSATTVEPTKEKLAPVESKETSEIQQAAVVEQKDVPVPET 6878
Query: 697 KTAVDE---RKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLA-FE 752
E K A E+++ E + E +K + E E V KLA E
Sbjct: 6879 SATTVEPTKEKLAPVESKETSEVQQAAIVE-QKDVPVPEANAPTFEPTVE----KLAPVE 6933
Query: 753 LSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAE 812
+T E + E+K + V + NA + ++ + E + + + ++ QA+ + K +
Sbjct: 6934 SKETSEVQQAAIVEQKDVPVPEANAPTVEPTVEKLAPVESKETSVESKETQADAKLKKEK 6993
Query: 813 D 813
D
Sbjct: 6994 D 6994
Score = 37.0 bits (84), Expect = 2.6
Identities = 43/205 (20%), Positives = 88/205 (41%), Gaps = 14/205 (6%)
Query: 622 IENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAG----ISDTKKEV 677
I N + K + E +++A + E V++L G S T+K+
Sbjct: 14980 IANTDRNKFKDRSLTESGEYVYQVTATGIHAVSSPSEETNPVKILVPGSEMPASKTEKKT 15039
Query: 678 NRLKKEHVEE--ERIVADSE-RKTAVDERKNAAAEARKLLEAPKKIAAEVEK----QIAK 730
+ K E ++ E IVA+ + ++ E A E +K + KK AE + Q K
Sbjct: 15040 DAAKSESEQKSAEEIVAEKQVDQSQASESTTEAVEEKKTKKVVKKKVAENKGEETLQEVK 15099
Query: 731 VELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSES 790
+L++ ++V + + + + S E+ ++ + +EK + +S KK+
Sbjct: 15100 EKLKKGKAVEKVQDESRRGSLQASSDNESVTTTSEKRSEAELEKNSEKSAEKKSTSADLE 15159
Query: 791 ELDK---KTADMEKQQAEEQKKLAE 812
DK + ++ K+ E++KK+ +
Sbjct: 15160 AADKAETEKSETGKETTEKKKKVVK 15184
Score = 36.2 bits (82), Expect = 4.5
Identities = 63/280 (22%), Positives = 109/280 (38%), Gaps = 76/280 (27%)
Query: 527 ISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPE 586
+S +E N +K +V SE + E+K AA++ ++A++I EK V
Sbjct: 15011 VSSPSEETNPVKI-------LVPGSEMPASKTEKKTDAAKSESEQKSAEEIVAEKQVDQS 15063
Query: 587 PANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKSEIS 646
A+ + +KK +KV + A KG E L+ +KLKK V ++ E
Sbjct: 15064 QASESTTEAVEEKKTKKVVKKKVAEN-------KGEETLQEVKEKLKKGKAVEKVQDE-- 15114
Query: 647 ALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAVDERKNA 706
+R G+ L+A + E + SE+++ + KN+
Sbjct: 15115 ---------SRRGS-----LQASS---------------DNESVTTTSEKRSEAELEKNS 15145
Query: 707 AAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAE 766
A K K +A++E A + K T + E
Sbjct: 15146 EKSAEK-----KSTSADLEA-----------------------ADKAETEKSETGKETTE 15177
Query: 767 KKKLLVEKINAESKIKKAQERSESELDK-KTADMEKQQAE 805
KKK +V+K+ + +K ++S+ EL K ++ Q AE
Sbjct: 15178 KKKKVVKKVAKKGLVK--ADKSKIELTAGKEGEISAQVAE 15215
>gb|AAF58087.2| CG18255-PD, isoform D [Drosophila melanogaster]
gi|24653978|ref|NP_725510.1| CG18255-PD, isoform D
[Drosophila melanogaster]
Length = 7210
Score = 148 bits (373), Expect = 8e-34
Identities = 212/835 (25%), Positives = 379/835 (45%), Gaps = 99/835 (11%)
Query: 16 SKCEELKKKCE--QVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEG 73
S +E +K E ++V + +A + +K +++ +++ KK K + E+++ + +E
Sbjct: 4224 SAIDEKSQKAEVSEIVSEKITEEKAQESQKKEVKDSKAKPKKAK--VLEKKSIEEAKLED 4281
Query: 74 KLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVK 133
K E A E A +SE + + I +E+AQ +++K E A + K
Sbjct: 4282 KKETQTDSAIDEKSQKAEVSEI--VSEKITDEKAQESQKEEVKDSE-------AKPKKAK 4332
Query: 134 ILEKRI---ENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALK-SENK 189
+LEK+ E LE++ +K + +E++Q+ E EK A E++ +K SE K
Sbjct: 4333 VLEKKSIEEEKLENKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKGSEAK 4392
Query: 190 KLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDR 249
K +LE+++ + +E K E A E A SE + + I DE+AQ
Sbjct: 4393 PKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEI--VSEKITDEKAQ------ 4444
Query: 250 LKKKCEKVVEGRNALRQAVKILEKGIENLESENKK-LKKDIQEEHAQRKVEIEGKL--EI 306
+ + E+V + ++A + +K IE + E+KK + D + +K E+ + +I
Sbjct: 4445 -ESQKEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKI 4503
Query: 307 SNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSEN 366
++ A + SE K K +LE+++ + +E K E A E A SE
Sbjct: 4504 TDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEI 4563
Query: 367 KKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQ 426
+ + I +E+AQ +++K A + K+LEK +++E E + KK+ Q
Sbjct: 4564 --VSEKITDEKAQESQKEEVKDS--------EAKPKKAKVLEK--KSIEEEKLEDKKEKQ 4611
Query: 427 EEQAQRKIEIEGKLEISNAFA-------ALENEVSALKSESTKLKK-DILEEQAQIKVAI 478
E A E K E+S + A E+++ +K K KK +LE+++ + +
Sbjct: 4612 TESAID--EKSQKAEVSEIVSEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEAKL 4669
Query: 479 EEKLEISNAFAALENEVSALKSEIAA---LQQKCGAGSREGNGDVEVLKAGISDTEKEVN 535
E+K E A E A SEI + +K +E D E K+
Sbjct: 4670 EDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEA-------KPKKAK 4722
Query: 536 TLKKELVEKEKIVADSERKT--AVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSK 593
L+K+ +E+EK+ E++T A+DE K AE +++ ++KI EKA
Sbjct: 4723 VLEKKSIEEEKLEDKKEKQTESAIDE-KSQKAEVSEIV--SEKITDEKA----------- 4768
Query: 594 CDELKKKCEKVAVGRNALRQAVKILEK-GIENLESENKKLKKENEVSALKSEISALQQKC 652
E +KK K G A + K+LEK IE + E+KK K+ KS+ + + +
Sbjct: 4769 -QESQKKEVK---GSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIV 4824
Query: 653 GAGAREGNGDVEVLKAGISDTK---KEVNRLKKEHVEEERIVADSERKT--AVDERKNAA 707
+ E K + D++ K+ L+K+ +EEE++ E++T A+DE+ A
Sbjct: 4825 SEKITDEKAQ-ESQKKEVKDSEAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKA 4883
Query: 708 AEARKLLE------APKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATK 761
+ + E A + EV+ AK + +V +K + E K++ E +
Sbjct: 4884 EVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDE 4943
Query: 762 RFE-AEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAEDKL 815
+F+ AE + + EKI E KA+E + E+ A +K + E+K + E+KL
Sbjct: 4944 KFQKAEVSETVSEKITDE----KAEESRKEEVKDSEAKPKKAKVLEKKSIEEEKL 4994
Score = 144 bits (363), Expect = 1e-32
Identities = 227/856 (26%), Positives = 397/856 (45%), Gaps = 132/856 (15%)
Query: 3 SEKAVIPEPANCCSKCEELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQE 62
S+KA + E + E+ ++ ++ V G A + K+LEK +++E E + KK+ Q
Sbjct: 4360 SQKAEVSEIVSEKITDEKAQESQKKEVKGSEAKPKKAKVLEK--KSIEEEKLEDKKEKQT 4417
Query: 63 EQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVV 122
E A I+ K + + EVS ++SE I +E+AQ +++K E
Sbjct: 4418 ESA-----IDEKSQ--------KAEVSEIVSEK------ITDEKAQESQKEEVKDSE--- 4455
Query: 123 EGRNALRQAVKILEKR-IENLESENKK-LKKDIQEEQAQRKIEI-EGKLEKSNAFAALEN 179
A + K+LEK+ IE + E+KK + D ++ +K E+ E EK A E+
Sbjct: 4456 ----AKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQES 4511
Query: 180 EVSALK-SENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDIL 238
+ +K SE K K +LE+++ + +E K E A E A SE + + I
Sbjct: 4512 QKEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEI--VSEKIT 4569
Query: 239 DEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHAQRKV 298
DE+AQ + ++ V+ A + K+LEK +++E E + KK+ Q E A
Sbjct: 4570 DEKAQ--------ESQKEEVKDSEAKPKKAKVLEK--KSIEEEKLEDKKEKQTESAID-- 4617
Query: 299 EIEGKLEISNAFA-------ALENEVSALK-SENKKLKKDILEEQAQRKVAMEGKLEISN 350
E K E+S + A E+++ +K SE K K +LE+++ + +E K E
Sbjct: 4618 EKSQKAEVSEIVSEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQT 4677
Query: 351 AFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKG 410
A E A SE + + I +E+AQ + + E+V + ++A + +K
Sbjct: 4678 DSAIDEKSQKAEVSEI--VSEKITDEKAQ-------ESQKEEVKDSEAKPKKAKVLEKKS 4728
Query: 411 IENLESENKKLKK-----DIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSESTKLKK 465
IE + E+KK K+ D + ++A+ + K+ A + + EV SE+ K
Sbjct: 4729 IEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKG--SEAKPKKA 4786
Query: 466 DILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKA 525
+LE+++ + +E+K E A E A SEI + +K + E K
Sbjct: 4787 KVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVS--EKITDEKAQ-----ESQKK 4839
Query: 526 GISDTE---KEVNTLKKELVEKEKIVADSERKT--AVDERKKAAAEARKLLEAAKKIAPE 580
+ D+E K+ L+K+ +E+EK+ E++T A+DE K AE +++ ++KI E
Sbjct: 4840 EVKDSEAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDE-KSQKAEVSEIV--SEKITDE 4896
Query: 581 KAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSA 640
KA E +KK K + A + K+LEK +++E E + KKE + +
Sbjct: 4897 KA------------QESQKKEVKDS---EAKPKKAKVLEK--KSIEEEKLEDKKEKQTES 4939
Query: 641 L------KSEIS-ALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVAD 693
K+E+S + +K E + EV + K +V L+K+ +EEE++
Sbjct: 4940 AIDEKFQKAEVSETVSEKITDEKAEESRKEEVKDSEAKPKKAKV--LEKKSIEEEKLEDK 4997
Query: 694 SERKT--AVDERKNAAAEAR---------KLLEAPKKIAAEVEKQIAK---VELRQVHLE 739
E++T A+DE+ A + K E+ KK + E + K +E + + +E
Sbjct: 4998 KEKQTESAIDEKSQKAEVSETVSEKITDEKAQESQKKEVKDSEAKPKKAKILEKKSIEIE 5057
Query: 740 KQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADM 799
K ++E+K K +K TK E ++++EKI+ E KA+E + EL A
Sbjct: 5058 K-LDEKKEKQTE--TKVATDTKSQTVEVSEIVLEKISEE----KAEESQKVELKDSEAKS 5110
Query: 800 EKQQAEEQKKLAEDKL 815
+K + E+K ++KL
Sbjct: 5111 KKAKVLEKKSTLKEKL 5126
Score = 143 bits (361), Expect = 2e-32
Identities = 213/839 (25%), Positives = 380/839 (44%), Gaps = 100/839 (11%)
Query: 3 SEKAVIPEPANCCSKCEELKKKCEQVVVGRNALRQAVKILEK-GIENLESENKKLKKDIQ 61
S+KA + E + E+ ++ ++ V A + K+LEK IE + ENKK K
Sbjct: 4295 SQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLENKKEK---- 4350
Query: 62 EEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKV 121
Q + AI+ K + + EVS ++SE I +E+AQ + +K
Sbjct: 4351 ----QTESAIDEKSQ--------KAEVSEIVSEK------ITDEKAQ-------ESQKKE 4385
Query: 122 VEGRNALRQAVKILEKRI---ENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALE 178
V+G A + K+LEK+ E LE + +K + +E++Q+ E EK A E
Sbjct: 4386 VKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQE 4445
Query: 179 NEVSALK-SENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDI 237
++ +K SE K K +LE+++ + +E K E A E A SE + + I
Sbjct: 4446 SQKEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEI--VSEKI 4503
Query: 238 LDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKK-LKKDIQEEHAQR 296
DE+AQ + + E+V + ++A + +K IE + E+KK + D + +
Sbjct: 4504 TDEKAQ-------ESQKEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQ 4556
Query: 297 KVEIEGKL--EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAA 354
K E+ + +I++ A + SE K K +LE+++ + +E K E A
Sbjct: 4557 KAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAI 4616
Query: 355 LENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENL 414
E A SE + + I +E+AQ + + E+V + ++A + +K IE
Sbjct: 4617 DEKSQKAEVSEI--VSEKITDEKAQ-------ESQMEEVKDSEAKPKKAKVLEKKSIEEA 4667
Query: 415 ESENKK-LKKDIQEEQAQRKIEIEGKL--EISNAFAALENEVSALKSESTKLKKDILEEQ 471
+ E+KK + D ++ +K E+ + +I++ A + SE+ K +LE++
Sbjct: 4668 KLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKK 4727
Query: 472 AQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTE 531
+ + +E+K E A E A SEI + +K + + EV G
Sbjct: 4728 SIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVS--EKITDEKAQESQKKEV--KGSEAKP 4783
Query: 532 KEVNTLKKELVEKEKIVADSERKT--AVDERKKAAAEARKLLEAAKKIAPEKAVIPEPAN 589
K+ L+K+ +E+EK+ E++T A+DE K AE +++ ++KI EKA
Sbjct: 4784 KKAKVLEKKSIEEEKLEDKKEKQTESAIDE-KSQKAEVSEIV--SEKITDEKA------- 4833
Query: 590 CCSKCDELKKKCEKVAVGRNALRQAVKILEK-GIENLESENKKLKKENEVSALKSEISAL 648
E +KK K + A + K+LEK IE + ENKK K+ KS+ + +
Sbjct: 4834 -----QESQKKEVKDS---EAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAEV 4885
Query: 649 QQKCGAGAREGNGDVEVLKAGISDTK---KEVNRLKKEHVEEERIVADSERKT--AVDER 703
+ + E K + D++ K+ L+K+ +EEE++ E++T A+DE+
Sbjct: 4886 SEIVSEKITDEKAQ-ESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 4944
Query: 704 KNAAAEARKLLE------APKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTK 757
A + + E A + EV+ AK + +V +K + E K+ E K K
Sbjct: 4945 FQKAEVSETVSEKITDEKAEESRKEEVKDSEAKPKKAKVLEKKSIEEEKL----EDKKEK 5000
Query: 758 EATKRFEAEKKKLLV-EKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAEDKL 815
+ + + +K V E ++ + +KAQE + E+ A +K + E+K + +KL
Sbjct: 5001 QTESAIDEKSQKAEVSETVSEKITDEKAQESQKKEVKDSEAKPKKAKILEKKSIEIEKL 5059
Score = 142 bits (357), Expect = 6e-32
Identities = 217/837 (25%), Positives = 381/837 (44%), Gaps = 103/837 (12%)
Query: 16 SKCEELKKKCE--QVVVGRNALRQAVKILEKGIENLESENKKLK----KDIQEEQAQRKV 69
S +E +K E ++V +A + +K +++ E++ KK K K I+EE+ + K
Sbjct: 4159 SAIDEKSQKAEVSEIVSENITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKK 4218
Query: 70 AIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALR 129
E + E + + + EVS ++SE I EE+AQ + +K V+ A
Sbjct: 4219 --EKQTESAIDEKSQKAEVSEIVSEK------ITEEKAQ-------ESQKKEVKDSKAKP 4263
Query: 130 QAVKILEKR-IENLESENKK-LKKDIQEEQAQRKIEI-EGKLEKSNAFAALENEVSALK- 185
+ K+LEK+ IE + E+KK + D ++ +K E+ E EK A E++ +K
Sbjct: 4264 KKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKD 4323
Query: 186 SENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGK 245
SE K K +LE+++ + +E K E A E A SE + + I DE+AQ
Sbjct: 4324 SEAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAEVSEI--VSEKITDEKAQ-- 4379
Query: 246 FCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHA----QRKVEIE 301
+ +K V+G A + K+LEK +++E E + KK+ Q E A +K E+
Sbjct: 4380 ------ESQKKEVKGSEAKPKKAKVLEK--KSIEEEKLEDKKEKQTESAIDEKSQKAEVS 4431
Query: 302 GKL--EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEV 359
+ +I++ A + SE K K +LE+++ + +E K E A E
Sbjct: 4432 EIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQ 4491
Query: 360 SALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENK 419
A SE + + I +E+AQ + + E+V + ++A + +K IE + E+K
Sbjct: 4492 KAEVSEI--VSEKITDEKAQ-------ESQKEEVKDSEAKPKKAKVLEKKSIEEAKLEDK 4542
Query: 420 K-LKKDIQEEQAQRKIEIEGKL--EISNAFAALENEVSALKSESTKLKKDILEEQAQIKV 476
K + D ++ +K E+ + +I++ A + SE+ K +LE+++ +
Sbjct: 4543 KETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEE 4602
Query: 477 AIEEKLEISNAFAALENEVSALKSEIAA---LQQKCGAGSREGNGDVEVLKAGISDTEKE 533
+E+K E A E A SEI + +K E D E K+
Sbjct: 4603 KLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQMEEVKDSEA-------KPKK 4655
Query: 534 VNTLKKELVEKEKIVADSERKT--AVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCC 591
L+K+ +E+ K+ E +T A+DE K AE +++ ++KI EKA +
Sbjct: 4656 AKVLEKKSIEEAKLEDKKETQTDSAIDE-KSQKAEVSEIV--SEKITDEKAQESQKEEV- 4711
Query: 592 SKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEV---SALKSEISAL 648
K E K K KV + +K IE + E+KK K+ + K+E+S +
Sbjct: 4712 -KDSEAKPKKAKV------------LEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEI 4758
Query: 649 QQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKT--AVDERKNA 706
+ + + +K + KK L+K+ +EEE++ E++T A+DE+
Sbjct: 4759 VSEKITDEKAQESQKKEVKGSEAKPKK-AKVLEKKSIEEEKLEDKKEKQTESAIDEKSQK 4817
Query: 707 AAEARKLLE------APKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEAT 760
A + + E A + EV+ AK + +V +K + E K++ E +T+ A
Sbjct: 4818 AEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLENKKE-KQTESAI 4876
Query: 761 --KRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAEDKL 815
K +AE +++ EKI E KAQE + E+ A +K + E+K + E+KL
Sbjct: 4877 DEKSQKAEVSEIVSEKITDE----KAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKL 4929
Score = 140 bits (353), Expect = 2e-31
Identities = 224/885 (25%), Positives = 393/885 (44%), Gaps = 171/885 (19%)
Query: 3 SEKAVIPEPANCCSKCEELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQE 62
S+KA + E + E+ ++ ++ V G A + K+LEK +++E E + KK+ Q
Sbjct: 3840 SQKAEVSEIVSEKITDEKAQESQKKEVKGSEAKPKKAKVLEK--KSIEEEKLEDKKEKQT 3897
Query: 63 EQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVV 122
E A I+ K + + EVS ++SE I +E+AQ +++K E
Sbjct: 3898 ESA-----IDEKSQ--------KAEVSEIVSEK------ITDEKAQESQMEEVKDSE--- 3935
Query: 123 EGRNALRQAVKILEKRI---ENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALEN 179
A + K+LEK+ E LE++ +K + +E++Q+ E EK A E+
Sbjct: 3936 ----AKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQES 3991
Query: 180 EVSALK-SENKKLKKDILEEQAQRKVAMEGKLEISNAFAALEN----EVSALKSENKKLK 234
+ +K SE K K +LE+++ + +E K E A E EVS + SEN
Sbjct: 3992 QKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEN---- 4047
Query: 235 QDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHA 294
I DE+AQ + +K V+ A + K+LEK +++E E + KK+ Q + A
Sbjct: 4048 --ITDEKAQ--------ESQKKEVKDSEAKPKKAKVLEK--KSIEEEKLEDKKETQTDSA 4095
Query: 295 ----QRKVEIEGKL--EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEI 348
+K E+ + +I++ A + SE K K +LE+++ + +E K E
Sbjct: 4096 IDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEK 4155
Query: 349 SNAFAALEN----EVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAV 404
A E EVS + SEN I +E+AQ + +K V+ A +
Sbjct: 4156 QTESAIDEKSQKAEVSEIVSEN------ITDEKAQ--------ESQKKEVKDSEAKPKKA 4201
Query: 405 KILEK-GIENLESENKKLKK-----DIQEEQAQRKIEIEGKLEISNAFAALENEVSALKS 458
K+LEK IE + E+KK K+ D + ++A+ + K+ A + + EV K+
Sbjct: 4202 KVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITEEKAQESQKKEVKDSKA 4261
Query: 459 ESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAA---LQQKCGAGSRE 515
+ K K +LE+++ + +E+K E A E A SEI + +K +E
Sbjct: 4262 KPKKAK--VLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKE 4319
Query: 516 GNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKT--AVDERKKAAAEARKLLEA 573
D E K+ L+K+ +E+EK+ E++T A+DE K AE +++
Sbjct: 4320 EVKDSEA-------KPKKAKVLEKKSIEEEKLENKKEKQTESAIDE-KSQKAEVSEIV-- 4369
Query: 574 AKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLK 633
++KI EKA E +KK K G A + K+LEK +++E E + K
Sbjct: 4370 SEKITDEKA------------QESQKKEVK---GSEAKPKKAKVLEK--KSIEEEKLEDK 4412
Query: 634 KENEVSAL------KSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEE 687
KE + + K+E+S + + + E +K + KK L+K+ +EE
Sbjct: 4413 KEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKK-AKVLEKKSIEE 4471
Query: 688 ERIVADSERKT--AVDER---------------------------KNAAAEARKLLEAPK 718
++ E +T A+DE+ K++ A+ +K K
Sbjct: 4472 AKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEK 4531
Query: 719 KIAAE--------------VEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFE 764
K E ++++ K E+ ++ EK +E+ + E K EA +
Sbjct: 4532 KSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEA----K 4587
Query: 765 AEKKKLLVEKINAESKIK-KAQERSESELDKKTADMEKQQAEEQK 808
+K K+L +K E K++ K ++++ES +D+K+ E + +K
Sbjct: 4588 PKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEK 4632
Score = 139 bits (351), Expect = 3e-31
Identities = 208/816 (25%), Positives = 370/816 (44%), Gaps = 87/816 (10%)
Query: 35 LRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVA-IEGKLEI-SNTFAALENEVSALI 92
L ++L+ IEN+++ I+++ A I GK+ + S + EV L
Sbjct: 3386 LDDETEVLKPKIENIKTTLLSDYDYIEKKDGPLLTAVINGKINVVSQHILTIIEEVKQLT 3445
Query: 93 SENKKLKQDILEEQAQGKICDQLKKCEKV-VEGRNALRQAVKILEKRI---ENLESENKK 148
+ + ++D+ +A ++ ++ +K ++ A + K+ EK+ E LE + +K
Sbjct: 3446 ENHDQKEKDVSNAEADNFADEKREESQKEEIKDSEAKHKKSKVSEKKSIEEEKLEDKKEK 3505
Query: 149 LKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALK-SENKKLKKDILEEQAQRKVAME 207
+ +E++Q+ E EK A E++ +K SE K K +LE+++ + +E
Sbjct: 3506 QTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLE 3565
Query: 208 GKLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQA 267
K E A E A SE + + I DE+AQ + +K V+ A +
Sbjct: 3566 DKKEKQTESAIDEKSQKAEVSEI--VSEKITDEKAQ--------ESQKKEVKDSEAKPKK 3615
Query: 268 VKILEK-GIENLESENKK-LKKDIQEEHAQRKVEIEGKL--EISNAFAALENEVSALKSE 323
K+LEK IE + E+KK + D + +K E+ + +I++ A + SE
Sbjct: 3616 AKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSETVSEKITDEKAQESQKEEVKDSE 3675
Query: 324 NKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFC 383
K K +LE+++ + +E K E A E A SE + + I +E+AQ
Sbjct: 3676 AKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEI--VSEKITDEKAQ---- 3729
Query: 384 DQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEIS 443
+ +K V+ A + K+LEK +++E E + KK+ Q + A E K E+S
Sbjct: 3730 ----ESQKKEVKDSEAKPKKAKVLEK--KSIEEEKLEDKKETQTDSAID--EKSQKAEVS 3781
Query: 444 NAFA-------ALENEVSALKSESTKLKK-DILEEQAQIKVAIEEKLEISNAFAALENEV 495
+ A E++ +K K KK +LE+++ + +E+K E A E
Sbjct: 3782 EIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQ 3841
Query: 496 SALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKT 555
A SEI + +K + + EV G K+ L+K+ +E+EK+ E++T
Sbjct: 3842 KAEVSEIVS--EKITDEKAQESQKKEV--KGSEAKPKKAKVLEKKSIEEEKLEDKKEKQT 3897
Query: 556 --AVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQ 613
A+DE K AE +++ ++KI EKA S+ +E+K A +
Sbjct: 3898 ESAIDE-KSQKAEVSEIV--SEKITDEKAQE-------SQMEEVKDS--------EAKPK 3939
Query: 614 AVKILEK-GIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISD 672
K+LEK IE + ENKK K+ KS+ + + + + E K + D
Sbjct: 3940 KAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQ-ESQKKEVKD 3998
Query: 673 TK---KEVNRLKKEHVEEERIVADSERKT--AVDERKNAAAEARKLLE------APKKIA 721
++ K+ L+K+ +EEE++ E++T A+DE+ A + + E A +
Sbjct: 3999 SEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSENITDEKAQESQK 4058
Query: 722 AEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEAT--KRFEAEKKKLLVEKINAES 779
EV+ AK + +V +K + E K++ E ++T A K +AE +++ EKI E
Sbjct: 4059 KEVKDSEAKPKKAKVLEKKSIEEEKLEDKKE-TQTDSAIDEKSQKAEVSEIVSEKITDE- 4116
Query: 780 KIKKAQERSESELDKKTADMEKQQAEEQKKLAEDKL 815
KAQE + E+ A +K + E+K + E+KL
Sbjct: 4117 ---KAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKL 4149
Score = 139 bits (350), Expect = 4e-31
Identities = 199/790 (25%), Positives = 359/790 (45%), Gaps = 97/790 (12%)
Query: 50 ESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQG 109
+SE K K + E+++ + +E K E A E A +SE + + I +E+AQ
Sbjct: 3478 DSEAKHKKSKVSEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEI--VSEKITDEKAQ- 3534
Query: 110 KICDQLKKCEKVVEGRNALRQAVKILEKRI---ENLESENKKLKKDIQEEQAQRKIEIEG 166
+ +K V+G A + K+LEK+ E LE + +K + +E++Q+ E
Sbjct: 3535 ------ESQKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEI 3588
Query: 167 KLEKSNAFAALENEVSALK-SENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSA 225
EK A E++ +K SE K K +LE+++ + +E K E A E A
Sbjct: 3589 VSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKA 3648
Query: 226 LKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKL 285
SE + + I DE+AQ + + E+V + ++A + +K IE + E+KK
Sbjct: 3649 EVSET--VSEKITDEKAQ-------ESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKE 3699
Query: 286 KK-----DIQEEHAQRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKV 340
K+ D + + A+ + K+ A + + EV +++ KK K +LE+++ +
Sbjct: 3700 KQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAK--VLEKKSIEEE 3757
Query: 341 AMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNAL 400
+E K E A E A SE + + I +E+AQ + + E+V +
Sbjct: 3758 KLEDKKETQTDSAIDEKSQKAEVSEI--VSEKITDEKAQ-------ESQKEEVKDSEAKP 3808
Query: 401 RQAVKILEKGIENLESENKKLKK-----DIQEEQAQRKIEIEGKLEISNAFAALENEVSA 455
++A + +K IE + E+KK K+ D + ++A+ + K+ A + + EV
Sbjct: 3809 KKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKG 3868
Query: 456 LKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAA---LQQKCGAG 512
SE+ K +LE+++ + +E+K E A E A SEI + +K
Sbjct: 3869 --SEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQES 3926
Query: 513 SREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKT--AVDERKKAAAEARKL 570
E D E K+ L+K+ +E+EK+ E++T A+DE K AE ++
Sbjct: 3927 QMEEVKDSEA-------KPKKAKVLEKKSIEEEKLENKKEKQTESAIDE-KSQKAEVSEI 3978
Query: 571 LEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEK-GIENLESEN 629
+ ++KI EKA E +KK K + A + K+LEK IE + E+
Sbjct: 3979 V--SEKITDEKA------------QESQKKEVKDS---EAKPKKAKVLEKKSIEEEKLED 4021
Query: 630 KKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTK---KEVNRLKKEHVE 686
KK K+ KS+ + + + + E K + D++ K+ L+K+ +E
Sbjct: 4022 KKEKQTESAIDEKSQKAEVSEIVSENITDEKAQ-ESQKKEVKDSEAKPKKAKVLEKKSIE 4080
Query: 687 EERIVADSERKT--AVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNE 744
EE++ E +T A+DE K+ AE +++ +KI E ++ K E++ +E
Sbjct: 4081 EEKLEDKKETQTDSAIDE-KSQKAEVSEIVS--EKITDEKAQESQKEEVKD-------SE 4130
Query: 745 RKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQA 804
K K A L K ++ E +K+K I+ +K+Q+ SE+ + EK Q
Sbjct: 4131 AKPKKAKVLEKKSIEEEKLEDKKEKQTESAID-----EKSQKAEVSEIVSENITDEKAQE 4185
Query: 805 EEQKKLAEDK 814
++K++ + +
Sbjct: 4186 SQKKEVKDSE 4195
Score = 107 bits (268), Expect = 1e-21
Identities = 183/810 (22%), Positives = 358/810 (43%), Gaps = 107/810 (13%)
Query: 60 IQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCE 119
++E + + +G ++ + + EVS +I+E K+ ++ +EE + + + K E
Sbjct: 3068 LEERELEASAQKQGDQDVEKK--SQKPEVSEVIAE--KISEEKIEEPKKPEEKETEVKSE 3123
Query: 120 K--VVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAAL 177
K V++ + + ++ ++ + + E K K ++ E A++ E GK+E+
Sbjct: 3124 KATVLDKQVLEEKELEASAQKQGDQDVEKKSQKPEVSEVVAEKVSE--GKIEEPKKPEVK 3181
Query: 178 ENEVSALKS---ENKKLKKDILEEQAQRKVAMEGKLE----------ISNAFAALENEVS 224
E EV + K+ + + L++ LE AQ++ +GK ++ AL + V
Sbjct: 3182 ETEVKSEKATTLDKQVLEEKELEASAQKQGDQDGKSRDDIIKTLKERLTELSKALGSSVD 3241
Query: 225 ALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVK-ILEKGIENL----- 278
+ E++++ ++ D++ K +L+ +G+ K + E IE L
Sbjct: 3242 EILRESREIVNNLEDDKVVAKHLFKLRDHIVHTYDGKRGEENKEKELFESFIELLCEASP 3301
Query: 279 -ESENKKLK--KDIQEEHAQRKVEIEGKLEISNAFAA--------LENEVSALKSENKKL 327
+E KL K+I+ K I+ ++ SN F L E A+K +++
Sbjct: 3302 EAAEKVKLNYLKEIKTNVILTKATIQ-LIDDSNMFTKPSLLIPKLLNLERVAVKIQSETY 3360
Query: 328 KKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLK 387
E+ + ++ I + F L++E LK + + +K +L + D ++
Sbjct: 3361 VDKSSEKMISLQQSLMDIFVILDDF--LDDETEVLKPKIENIKTTLLSDY------DYIE 3412
Query: 388 KK----CEKVVEGR-NALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEI 442
KK V+ G+ N + Q + + + ++ L + + +KD+ +A + + +
Sbjct: 3413 KKDGPLLTAVINGKINVVSQHILTIIEEVKQLTENHDQKEKDVSNAEADNFADEKRE--- 3469
Query: 443 SNAFAALENEVSALKSESTKLKKDILEEQAQIKVA-IEEKLEISNAFAALENEVSALKSE 501
E++ +K K KK + E+ I+ +E+K E A E A SE
Sbjct: 3470 -------ESQKEEIKDSEAKHKKSKVSEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSE 3522
Query: 502 IAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKT--AVDE 559
I + +K + + EV G K+ L+K+ +E+EK+ E++T A+DE
Sbjct: 3523 IVS--EKITDEKAQESQKKEV--KGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDE 3578
Query: 560 RKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILE 619
K AE +++ ++KI EKA E +KK K + A + K+LE
Sbjct: 3579 -KSQKAEVSEIV--SEKITDEKA------------QESQKKEVKDS---EAKPKKAKVLE 3620
Query: 620 K-GIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTK---K 675
K IE + E+KK + + KS+ + + + + E K + D++ K
Sbjct: 3621 KKSIEEAKLEDKKETQTDSAIDEKSQKAEVSETVSEKITDEKAQ-ESQKEEVKDSEAKPK 3679
Query: 676 EVNRLKKEHVEEERIVADSERKT--AVDERKNAAAEARKLLE------APKKIAAEVEKQ 727
+ L+K+ +EEE++ E++T A+DE+ A + + E A + EV+
Sbjct: 3680 KAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDS 3739
Query: 728 IAKVELRQVHLEKQVNERKMKLAFELSKTKEAT--KRFEAEKKKLLVEKINAESKIKKAQ 785
AK + +V +K + E K++ E ++T A K +AE +++ EKI E KAQ
Sbjct: 3740 EAKPKKAKVLEKKSIEEEKLEDKKE-TQTDSAIDEKSQKAEVSEIVSEKITDE----KAQ 3794
Query: 786 ERSESELDKKTADMEKQQAEEQKKLAEDKL 815
E + E+ A +K + E+K + E+KL
Sbjct: 3795 ESQKEEVKDSEAKPKKAKVLEKKSIEEEKL 3824
Score = 96.7 bits (239), Expect = 3e-18
Identities = 185/868 (21%), Positives = 369/868 (42%), Gaps = 132/868 (15%)
Query: 19 EELKKKCEQVVVGRNALRQAVKILEKGIENLESENKKLKKDIQEEQA---QRKVAIEGKL 75
++++KK ++ V A KI E+ IE + K +I+ E+A ++V E +L
Sbjct: 2888 QDVEKKFQKAEVSEVV---AEKISEETIEEPKKPEVK-DTEIKSEKATALDKQVLEEKEL 2943
Query: 76 EISNTFAALENEVSALISENKKLKQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKIL 135
E S ++ S+ ++ + I E+ ++ KI + K EK E ++ + +L
Sbjct: 2944 EASAQKQGDQDVEKK--SQKPEVSEVIAEKISEEKIEEPKKPEEKETEVKS---EKATVL 2998
Query: 136 EKRIENLESENKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDI 195
+K++ E K+L+ Q++ Q ++E + +K + +VS K E K K ++
Sbjct: 2999 DKQV----LEEKELEASAQKQGDQ---DVEKRSQKPEVSEVVAEKVSEGKIEEPK-KPEV 3050
Query: 196 LEEQAQRKVAMEGKLEISN-----AFAALENEVSALKSENKKLKQDILDEQAQGKFCDRL 250
E +A+ + A +++ A A + + K K +++ E+ + +
Sbjct: 3051 KETEAKSEKATTLDMQVLEERELEASAQKQGDQDVEKKSQKPEVSEVIAEKISEEKIEEP 3110
Query: 251 KKKCEKVVEGRNALRQAVKILEKGI-ENLESENKKLKKDIQE-EHAQRKVEI-------- 300
KK EK E ++ + +L+K + E E E K+ Q+ E +K E+
Sbjct: 3111 KKPEEKETEVKS---EKATVLDKQVLEEKELEASAQKQGDQDVEKKSQKPEVSEVVAEKV 3167
Query: 301 -EGKLEISNAFAALENEVSALKS---ENKKLKKDILEEQAQRKVAMEGKLE--------- 347
EGK+E E EV + K+ + + L++ LE AQ++ +GK
Sbjct: 3168 SEGKIEEPKKPEVKETEVKSEKATTLDKQVLEEKELEASAQKQGDQDGKSRDDIIKTLKE 3227
Query: 348 -ISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNALRQAVK- 405
++ AL + V + E++++ ++ +++ K +L+ +G+ K
Sbjct: 3228 RLTELSKALGSSVDEILRESREIVNNLEDDKVVAKHLFKLRDHIVHTYDGKRGEENKEKE 3287
Query: 406 ILEKGIENL------ESENKKLK--KDIQEEQAQRKIEIEGKLEISNAFAA--------L 449
+ E IE L +E KL K+I+ K I+ ++ SN F L
Sbjct: 3288 LFESFIELLCEASPEAAEKVKLNYLKEIKTNVILTKATIQ-LIDDSNMFTKPSLLIPKLL 3346
Query: 450 ENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEV---------SALKS 500
E A+K +S E+ ++ ++ + I + F E EV + L S
Sbjct: 3347 NLERVAVKIQSETYVDKSSEKMISLQQSLMDIFVILDDFLDDETEVLKPKIENIKTTLLS 3406
Query: 501 EIAALQQKCGAG-SREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDE 559
+ +++K G + NG + V+ I +EV L + +KEK V+++E DE
Sbjct: 3407 DYDYIEKKDGPLLTAVINGKINVVSQHILTIIEEVKQLTENHDQKEKDVSNAEADNFADE 3466
Query: 560 RKKAAAEARKLLEAAK----KIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAV 615
+++ + + AK K++ +K++ E K ++ K+K + A+ + + V
Sbjct: 3467 KREESQKEEIKDSEAKHKKSKVSEKKSIEEE------KLEDKKEKQTESAIDEKSQKAEV 3520
Query: 616 KILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKK 675
E ++K+ E + K E+ + K K
Sbjct: 3521 S---------EIVSEKITDEKAQESQKKEVKGSEAK----------------------PK 3549
Query: 676 EVNRLKKEHVEEERIVADSERKT--AVDERKNAAAEARKLLE------APKKIAAEVEKQ 727
+ L+K+ +EEE++ E++T A+DE+ A + + E A + EV+
Sbjct: 3550 KAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDS 3609
Query: 728 IAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQER 787
AK + +V +K + E K++ + +T+ + E +K + E ++ + +KAQE
Sbjct: 3610 EAKPKKAKVLEKKSIEEAKLE---DKKETQTDSAIDEKSQKAEVSETVSEKITDEKAQES 3666
Query: 788 SESELDKKTADMEKQQAEEQKKLAEDKL 815
+ E+ A +K + E+K + E+KL
Sbjct: 3667 QKEEVKDSEAKPKKAKVLEKKSIEEEKL 3694
Score = 96.7 bits (239), Expect = 3e-18
Identities = 182/856 (21%), Positives = 366/856 (42%), Gaps = 147/856 (17%)
Query: 39 VKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALISENKKL 98
+ L+ I NL+ + KL + E Q+Q ++S+ +AL+ ++ + E
Sbjct: 2190 IDALQLQISNLQEKLNKLNVFLSELQSQS--------DVSSPESALDTDID--LKEGSGS 2239
Query: 99 KQDILEEQAQGKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESENKKLKKDIQEEQA 158
++DI E + K+ + ++ + K+ E E K+ +++
Sbjct: 2240 QEDIEPEAKRPKMLESEQQLDSY---------------KQTETQEEVPKET-----DDET 2279
Query: 159 QRKIEIEGKLEKSNAFAALENEVSALK-SENKKLKK--------------DILEEQAQRK 203
++ IE+E KLE N A ++E A K SE +KL++ +++ ++A +
Sbjct: 2280 KKDIEVESKLENQNELVAKKDEQKADKVSEQEKLQESKQQTEVDDTQKSTEVVSQKASPE 2339
Query: 204 VAMEG---KLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKKCEKVVEG 260
+E KL S A +E+ + +E + + +I + + K +L++ +G
Sbjct: 2340 NILEALSEKLSQSPNNATQNDEIKTIMTECQDILDNIDNIEKVSKSIFKLREHIVHTFDG 2399
Query: 261 RNALRQAVK-ILEKGIENL--------ESENKKLKKDIQEEHAQRKVEIEGKLEISNAF- 310
+ Q K ++EK IE+L E + K+I+ K I+ ++ SN F
Sbjct: 2400 KPPEEQTEKELVEKLIESLFESCPEATEHVIQTYIKEIKTNIILTKAAIQ-LIDDSNLFT 2458
Query: 311 ---------------AALENEVSALKSENKK-------------LKKDILEEQAQR---K 339
+ L V + +K+ + D+L+E+ ++ K
Sbjct: 2459 KPSLLVPKLVNLEKLSELTQTVKLIDKSSKEMIGLQQNLMDIFIILDDLLDERTEKINPK 2518
Query: 340 VAMEGKLEISNAFAALENEVSALKSENKKLKQDILEEQAQGKFCDQLKKKCEKVVEGRNA 399
+ K+ +S + +E + L + K ++ E+ C++ K +++E +N
Sbjct: 2519 IENIKKILLSE-YDYIEKKEGQLNTAVVNGKIKLITEKIL-DICEEFK----QIIESQNQ 2572
Query: 400 LRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEVSALKSE 459
+ A ++K E + + ++K I+E + K +++ + A + E
Sbjct: 2573 NKDAAGDIKKS-ETEDVVDHSIEKKIEEPKRSEKKDLDKEFLEEKELKASAKKQGDQDIE 2631
Query: 460 STKLKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGD 519
K ++ E A+ K++ E K+E ++ E KSE A + K +E
Sbjct: 2632 QKSQKPEVSEVVAE-KIS-EGKIEEPKKPEEMDTEA---KSEKATVLDKQVLEEKELEAS 2686
Query: 520 VEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAP 579
E K G D EK K + E ++VA+ + ++E KK + + +++ K A
Sbjct: 2687 AE--KQGDQDVEK-----KSQKPEVSEVVAEKISEETIEEPKKPEVKDTE-IKSEKATAL 2738
Query: 580 EKAVIPE---PANCCSKCD-ELKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLK-- 633
+K V+ E A+ +CD +++KK +K V A KI EK IE E + ++K
Sbjct: 2739 DKQVLEEKELEASAQKQCDQDVEKKSQKPEVSEIV---AEKISEKTIE--EPKKPEVKDT 2793
Query: 634 --KENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERI- 690
K + +AL ++ ++ + ++G+ DVE K EV+ + E + EE I
Sbjct: 2794 EIKSEKATALDKQVLEEKELEASAQKQGDQDVEK-----KSQKPEVSEVVAEKISEETIE 2848
Query: 691 ----------VADSERKTAVDERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEK 740
SE+ T +D K E A K+ +VEK+ K E+ +V EK
Sbjct: 2849 EPKKPEVKETEVKSEKATVLD--KQVLEEKELEASAQKQGDQDVEKKFQKAEVSEVVAEK 2906
Query: 741 QVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIK-KAQERSESELDKKTADM 799
++E ++ E K + ++EK L +++ E +++ AQ++ + +++KK+
Sbjct: 2907 -ISEETIE---EPKKPEVKDTEIKSEKATALDKQVLEEKELEASAQKQGDQDVEKKSQKP 2962
Query: 800 EKQQAEEQKKLAEDKL 815
E + + K++E+K+
Sbjct: 2963 EVSEVIAE-KISEEKI 2977
Score = 93.2 bits (230), Expect = 3e-17
Identities = 174/807 (21%), Positives = 346/807 (42%), Gaps = 77/807 (9%)
Query: 35 LRQAVKILEKGIENLESENKKLKK------DIQEEQAQRKVAIEGKLEISNTFAALENEV 88
L Q VK+++K + + + L D+ +E+ ++ I K+E N L +E
Sbjct: 2476 LTQTVKLIDKSSKEMIGLQQNLMDIFIILDDLLDERTEK---INPKIE--NIKKILLSEY 2530
Query: 89 SALISENKKLKQDILEEQAQ---GKICDQLKKCEKVVEGRNALRQAVKILEKRIENLESE 145
+ + +L ++ + + KI D ++ ++++E +N + A ++K E +
Sbjct: 2531 DYIEKKEGQLNTAVVNGKIKLITEKILDICEEFKQIIESQNQNKDAAGDIKKS-ETEDVV 2589
Query: 146 NKKLKKDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALKSENKKLKKDILEEQAQRKVA 205
+ ++K I+E + K +++ + + A + E K K ++ E A++
Sbjct: 2590 DHSIEKKIEEPKRSEKKDLDKEFLEEKELKASAKKQGDQDIEQKSQKPEVSEVVAEK--I 2647
Query: 206 MEGKLEISNAFAALENEVSALKSENKKLKQDILDEQA--QGKFCDRLKKKCEKVVEGRNA 263
EGK+E ++ E KSE K +LD+Q + + +K+ ++ VE ++
Sbjct: 2648 SEGKIEEPKKPEEMDTEA---KSE----KATVLDKQVLEEKELEASAEKQGDQDVEKKSQ 2700
Query: 264 LRQAVKILEKGI--ENLESENKKLKKD--IQEEHA---QRKVEIEGKLEISNAFAALENE 316
+ +++ + I E +E K KD I+ E A ++V E +LE S A + +
Sbjct: 2701 KPEVSEVVAEKISEETIEEPKKPEVKDTEIKSEKATALDKQVLEEKELEAS-AQKQCDQD 2759
Query: 317 VSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAALENEVSALKSENKKLKQDILEE 376
V KS+ ++ + + E+ +++ + K E+ + E A + + L++ LE
Sbjct: 2760 VEK-KSQKPEVSEIVAEKISEKTIEEPKKPEVKDTEIKSE---KATALDKQVLEEKELEA 2815
Query: 377 QAQGKFCDQLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKIEI 436
AQ + ++KK +K A KI E+ IE E KK + E ++++ +
Sbjct: 2816 SAQKQGDQDVEKKSQKPEVSEVV---AEKISEETIE----EPKKPEVKETEVKSEKATVL 2868
Query: 437 EGKLEISNAFAALENEVSALKSESTKLKKDILEEQAQIKVAIEEKLEISNAFAALENEV- 495
+ E E SA K ++K ++A++ + EK+ + EV
Sbjct: 2869 D-----KQVLEEKELEASAQKQGDQDVEKKF--QKAEVSEVVAEKISEETIEEPKKPEVK 2921
Query: 496 -SALKSEIAALQQKCGAGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERK 554
+ +KSE A K +E + K G D EK+ + V EKI + +
Sbjct: 2922 DTEIKSEKATALDKQVLEEKELEASAQ--KQGDQDVEKKSQKPEVSEVIAEKISEEKIEE 2979
Query: 555 TAVDERKKAAAEARKLLEAAKKIAPEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQA 614
E K+ ++ K K++ EK + E + +++K+ +K V A
Sbjct: 2980 PKKPEEKETEVKSEKATVLDKQVLEEKEL--EASAQKQGDQDVEKRSQKPEVSEVV---A 3034
Query: 615 VKILEKGIENLESENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTK 674
K+ E IE + K + A ++ L+++ + + GD +V K K
Sbjct: 3035 EKVSEGKIEEPKKPEVKETEAKSEKATTLDMQVLEERELEASAQKQGDQDVEK---KSQK 3091
Query: 675 KEVNRLKKEHVEEERI---VADSERKTAVDERKNAAAEARKLLE------APKKIAAEVE 725
EV+ + E + EE+I E++T V K + + L E A K+ +VE
Sbjct: 3092 PEVSEVIAEKISEEKIEEPKKPEEKETEVKSEKATVLDKQVLEEKELEASAQKQGDQDVE 3151
Query: 726 KQIAKVELRQVHLEKQVNERKMKLAFELSKTKEATKRFEAEKKKLLVEKINAESKIKKAQ 785
K+ K E+ +V EK V+E K++ E K + ++EK L +++ E +++ +
Sbjct: 3152 KKSQKPEVSEVVAEK-VSEGKIE---EPKKPEVKETEVKSEKATTLDKQVLEEKELEASA 3207
Query: 786 ERSESELDKKTADMEKQQAEEQKKLAE 812
++ + K D+ K E +L++
Sbjct: 3208 QKQGDQDGKSRDDIIKTLKERLTELSK 3234
Score = 82.0 bits (201), Expect = 7e-14
Identities = 193/836 (23%), Positives = 358/836 (42%), Gaps = 138/836 (16%)
Query: 46 IENLESENK---KLKKDI--------QEEQAQRKVAIEGKLE--ISNTFAALENEVSALI 92
I+N+E +K KL++ I EEQ ++++ +E +E + A E+ + I
Sbjct: 2376 IDNIEKVSKSIFKLREHIVHTFDGKPPEEQTEKEL-VEKLIESLFESCPEATEHVIQTYI 2434
Query: 93 SENKKLKQDILEEQAQGKICDQLKKCEKV---------VEGRNALRQAVKILEKRIENLE 143
K++K +I+ +A ++ D K +E + L Q VK+++K + +
Sbjct: 2435 ---KEIKTNIILTKAAIQLIDDSNLFTKPSLLVPKLVNLEKLSELTQTVKLIDKSSKEMI 2491
Query: 144 SENKKLKK------DIQEEQAQR---KIEIEGKLEKSNAFAALENEVSALKSE--NKKLK 192
+ L D+ +E+ ++ KIE K+ S + +E + L + N K+K
Sbjct: 2492 GLQQNLMDIFIILDDLLDERTEKINPKIENIKKILLSE-YDYIEKKEGQLNTAVVNGKIK 2550
Query: 193 -------------KDILEEQAQRKVAMEGKLEISNAFAALENEVSAL-----KSENKKLK 234
K I+E Q Q K A G ++ S +++ + +SE K L
Sbjct: 2551 LITEKILDICEEFKQIIESQNQNKDAA-GDIKKSETEDVVDHSIEKKIEEPKRSEKKDLD 2609
Query: 235 QDILDEQAQGKFCDRLKKKCEKVVEGRNALRQAVKILEKGIENLESENKKLKKDIQEEHA 294
++ L+E+ + KK+ ++ +E ++ + +++ + I + E K +++ E
Sbjct: 2610 KEFLEEK---ELKASAKKQGDQDIEQKSQKPEVSEVVAEKISEGKIEEPKKPEEMDTEAK 2666
Query: 295 QRKVEIEGKLEISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAA 354
K + K + E + KK +K + E K++ E +E
Sbjct: 2667 SEKATVLDKQVLEEKELEASAEKQGDQDVEKKSQKPEVSEVVAEKISEE-TIEEPKKPEV 2725
Query: 355 LENEVSALKS---ENKKLKQDILEEQAQGKFCDQ-LKKKCEKVVEGRNALRQAVKILEKG 410
+ E+ + K+ + + L++ LE AQ K CDQ ++KK +K A KI EK
Sbjct: 2726 KDTEIKSEKATALDKQVLEEKELEASAQ-KQCDQDVEKKSQKPEVSEIV---AEKISEKT 2781
Query: 411 IENLESENKKLKKDIQEEQA---QRKIEIEGKLEISNAFAALENEVSALKSESTKLKKDI 467
IE + K +I+ E+A +++ E +LE S A + +V KS+ ++ + +
Sbjct: 2782 IEEPKKPEVK-DTEIKSEKATALDKQVLEEKELEAS-AQKQGDQDVEK-KSQKPEVSEVV 2838
Query: 468 LEEQAQIKVAIEEKLEISNAFAALENEVSALKSEIAALQQKCGAGSREGNGDVEVLKAGI 527
E+ ++ + +K E+ E EV KSE A + K +E + K G
Sbjct: 2839 AEKISEETIEEPKKPEVK------ETEV---KSEKATVLDKQVLEEKELEASAQ--KQGD 2887
Query: 528 SDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKLLEAAKKIAPEKAVIPEP 587
D EK K + E ++VA+ + ++E KK + ++ ++ K A +K V+ E
Sbjct: 2888 QDVEK-----KFQKAEVSEVVAEKISEETIEEPKKPEVKDTEI-KSEKATALDKQVLEEK 2941
Query: 588 ---ANCCSKCDE-LKKKCEKVAVGRNALRQAVKILEKGIENLESENKKLKKENEVSALKS 643
A+ + D+ ++KK +K V A KI E E +E K +KE EV + K+
Sbjct: 2942 ELEASAQKQGDQDVEKKSQKPEVSEVI---AEKISE---EKIEEPKKPEEKETEVKSEKA 2995
Query: 644 EI---SALQQKCGAGAREGNGDVEVLKAGISDTKKEVNRLKKEHVEEERIVADSERKTAV 700
+ L++K + + GD +V K K EV+ + E V E +I
Sbjct: 2996 TVLDKQVLEEKELEASAQKQGDQDVEKRS---QKPEVSEVVAEKVSEGKI---------- 3042
Query: 701 DERKNAAAEARKLLEAPKKIAAEVEKQIAKVELRQVHLEKQVNERKMKLAFELSKTKEAT 760
E PKK EV++ AK E + L+ QV E + E S K+
Sbjct: 3043 --------------EEPKK--PEVKETEAKSE-KATTLDMQVLEER---ELEASAQKQGD 3082
Query: 761 KRFEAEKKKLLVEKINAESKIKKAQERSESELDKKTADMEKQQAEEQKKLAEDKLL 816
+ E + +K V ++ AE ++ E + +K+T ++ K++ E+K L
Sbjct: 3083 QDVEKKSQKPEVSEVIAEKISEEKIEEPKKPEEKETEVKSEKATVLDKQVLEEKEL 3138
Score = 49.3 bits (116), Expect = 5e-04
Identities = 144/754 (19%), Positives = 296/754 (39%), Gaps = 102/754 (13%)
Query: 33 NALRQAVKILEKGIENLESENKKLKKDIQEEQAQRKVAIEGKLEISNTFAALENEVSALI 92
+A Q++ I+ IE ++ KL+ G+ +I +++ ++ L
Sbjct: 1016 SAADQSIAIIRNIIEPIKQIESKLR------------VYSGETQIDALIQSMDEDIRRLH 1063
Query: 93 SENKKLKQDILEEQAQGKICDQLKKC--EKVVEGRNALRQAVKILEKRIENLESENKKLK 150
+ +++ + ++ + + C + V E + +KI+ ++ E SE + +
Sbjct: 1064 MGLQVIEKCVEIDETGATLIQRTSVCIIDSVAEQMKRALEELKIVSRKFE---SECLRAQ 1120
Query: 151 KDIQEEQAQRKIEIEGKLEKSNAFAALENEVSALK--SENKKLKKDILEEQAQRKVAMEG 208
++ + Q+ +EI KS A E+ A K SE + +++ + + ++
Sbjct: 1121 IELTADDIQQGLEITQGTIKSQALLQEAQELEAAKHFSETVEKMQEVPDSMSFATISEAN 1180
Query: 209 KLEISNAFAALENEVSALKSENKKLKQDILDEQAQGKFCDRLKKK-CEKVVEGRNALRQA 267
++A + V+ ++ ++++ ++ E+++ + ++ +K E +VE L+
Sbjct: 1181 LPSEASALKDICQPVAKIQEALERVEMELSLEESEEQIYKKVHQKVLESIVEPIKQLQST 1240
Query: 268 VKILEKGIENL---ESENKK---------------LKKDIQEEHAQRKVEIEGKL----- 304
++ +E E+L ES +K LKK ++ ++ +EG +
Sbjct: 1241 LQSIEDKTESLAGSESIEQKINMAILDIVTPPLFELKKGLEVILNEKSGSVEGGMRTVST 1300
Query: 305 ---------EISNAFAALENEVSALKSENKKLKKDILEEQAQRKVAMEGKLEISNAFAAL 355
EI N A L E L+S + ++ L + VA KL S A A L
Sbjct: 1301 VESMVPPLQEIQNGLAQLGQE---LQSGQDSVPQEQLRSEPVMGVADTQKLLQSFAQAVL 1357
Query: 356 ENE-----VSALKSENKKLK------------QDILEEQAQGKFCDQLKKKCEKVVEGRN 398
E +SA S N K++ ILE + G + L + V E
Sbjct: 1358 HFETNIERISARLSPNVKIRLLNLKDELSALIGAILEREITGHHVELLDRLKRPVDELNY 1417
Query: 399 ALRQA-----VKILEKGIENLESENKKLKKDIQEEQAQRKIEIEGKLEISNAFAALENEV 453
+RQ L IE L + +K Q R+ + + + N + + N V
Sbjct: 1418 CIRQTEVKNMTGSLADLIEPLSMLQENTQKGHQRLLVAREPDQQALQTLDNIRSLIRNVV 1477
Query: 454 SALKSESTK-LKKDILEEQAQIKVAIEEKLEISNAFAALENEVSALKS--EIAALQQKCG 510
++ K L+++I +++ Q + ++ S LE +VS ++ I LQ+
Sbjct: 1478 IDIEEHEFKILQQEIQQDEEQ--ASQQQDKSFSALRKVLETKVSLEEAVGNIETLQEALN 1535
Query: 511 AGSREGNGDVEVLKAGISDTEKEVNTLKKELVEKEKIVADSERKTAVDERKKAAAEARKL 570
S V S E +V L+ + K + SE +T +D + A R L
Sbjct: 1536 KISENPKASERVKS---SSNEAQVYLLRILQIAK-GLATFSEAETTLDVNE--ANTTRIL 1589
Query: 571 LEAAKKIA--------PEKAVIPEPANCCSKCDELKKKCEKVAVGRNALRQAVKILEKGI 622
E K A PE E N ++ ++ + ++ + ++ + L +
Sbjct: 1590 FECGKSFADLAKALHSPESLTESEFINALNQFGDIVGQQKESMDEKLSIASPLSSLIHVL 1649
Query: 623 ENLE---SENKKLKKENEVSALKSEISALQQKCGAGAREGNGDVEVLKAGISDTKKEVNR 679
+NL+ + + L ++VS LKS +L +G + +SD + +
Sbjct: 1650 QNLKPPRASMEDLSTLDDVSVLKSVAESLPTDPDVEVPKGTEKPSTVAVLLSDLNQGITS 1709
Query: 680 LKKEHVEEERIVADSERKTAVDERKNAAAEARKL 713
+ H E+ +V+ S TA + + A + ++L
Sbjct: 1710 V-LSHSEDPDVVSLS--GTAAQQVQAALVKMQEL 1740
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.305 0.124 0.307
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,116,646,496
Number of Sequences: 2540612
Number of extensions: 47089810
Number of successful extensions: 510496
Number of sequences better than 10.0: 22237
Number of HSP's better than 10.0 without gapping: 1815
Number of HSP's successfully gapped in prelim test: 20926
Number of HSP's that attempted gapping in prelim test: 296903
Number of HSP's gapped (non-prelim): 103192
length of query: 824
length of database: 863,360,394
effective HSP length: 137
effective length of query: 687
effective length of database: 515,296,550
effective search space: 354008729850
effective search space used: 354008729850
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 80 (35.4 bits)
Lotus: description of TM0437b.7