Lotus
BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0288.8
         (846 letters)

Database: nr 
           2,540,612 sequences; 863,360,394 total letters

Searching..................................................done


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

emb|CAB78300.1| polyubiquitin-like protein [Arabidopsis thaliana...   767  0.0
pir||T07649 hypothetical protein T1P17.160 - Arabidopsis thalian...   362  2e-98
gb|EAA65131.1| hypothetical protein AN1966.2 [Aspergillus nidula...   204  1e-50
gb|EAK84580.1| hypothetical protein UM03442.1 [Ustilago maydis 5...   204  1e-50
gb|EAA51657.1| hypothetical protein MG03252.4 [Magnaporthe grise...   202  5e-50
gb|EAL89711.1| ubiquitin-protein ligase (Tom1), putative [Asperg...   199  2e-49
emb|CAB55856.1| SPAC1805.15c [Schizosaccharomyces pombe] gi|1911...   199  3e-49
gb|AAX79795.1| ubiquitin-protein ligase, putative [Trypanosoma b...   199  4e-49
gb|EAA65522.1| hypothetical protein AN1339.2 [Aspergillus nidula...   196  4e-48
ref|NP_067498.3| HECT, UBA and WWE domain containing 1 [Mus musc...   195  6e-48
ref|XP_576948.1| PREDICTED: similar to mKIAA0312 protein [Rattus...   195  6e-48
emb|CAI42354.1| upstream regulatory element binding protein 1 (U...   195  6e-48
emb|CAI42656.1| upstream regulatory element binding protein 1 (U...   195  6e-48
emb|CAI42644.1| upstream regulatory element binding protein 1 (U...   195  6e-48
ref|XP_538052.1| PREDICTED: similar to E3 ubiquitin protein liga...   195  6e-48
dbj|BAA20771.2| KIAA0312 [Homo sapiens]                               195  6e-48
gb|AAX24124.1| LASU1 [Mus musculus]                                   195  6e-48
gb|AAH63505.1| HUWE1 protein [Homo sapiens]                           195  6e-48
gb|AAH54372.1| Huwe1 protein [Mus musculus]                           195  6e-48
gb|AAH11391.1| Huwe1 protein [Mus musculus]                           195  6e-48

>emb|CAB78300.1| polyubiquitin-like protein [Arabidopsis thaliana]
           gi|5823568|emb|CAB41727.2| polyubiquitin-like protein
           [Arabidopsis thaliana] gi|25407523|pir||H85134
           polyubiquitin-like protein [imported] - Arabidopsis
           thaliana gi|15235410|ref|NP_192994.1| ubiquitin-protein
           ligase, putative [Arabidopsis thaliana]
          Length = 873

 Score =  767 bits (1981), Expect = 0.0
 Identities = 428/870 (49%), Positives = 561/870 (64%), Gaps = 61/870 (7%)

Query: 14  KRKHDEIDDDEGGVSD-IDPIRMKKDDA----AKAVYSAVHHRS---------------- 52
           KRK DE   D  GV++ ++ ++ ++ DA    A A  + +  RS                
Sbjct: 28  KRKRDEDSSDYVGVAESLEMLKKQEIDADHMAASAQQTLISWRSGENSRSLSSSGECSSS 87

Query: 53  -----IMLQFFVRMMGNGNTIVMQAHPDDTVQSIHERIQALKGIPVFEQRLIYNGKQLQS 107
                  LQ FVRMM  G TIV+ A   DTV+ +H+RI+    IP  EQR+IY GKQLQ 
Sbjct: 88  NRPESTRLQIFVRMMSGGKTIVIHAEKYDTVEKLHQRIEWKTKIPALEQRVIYKGKQLQR 147

Query: 108 EQTLAECSIGKDASLQLVGRMRSTGHPHAWQVINDMVSLVIRLCHNEPVHDANKTIKGLI 167
           E +L   SI +DASLQLV RM+ST HP AWQ I+D++  + R+   E   +    I   I
Sbjct: 148 ENSLTYYSIEQDASLQLVARMQSTEHPVAWQTIDDIMYTISRMYKGE---NLQSNINEKI 204

Query: 168 TSYLNLSPKNDNDSASGYFQIFMSAT--AVLVSLYLSPYTGNKDCADSSIRHFLTTCKTT 225
            ++  + P   ++S + Y  IF +++  A LV LY S    NK CA SS++ FL+ C   
Sbjct: 205 VTFFAMIPVESDESIAKYLNIFSNSSVPAALVMLYASSLERNKSCAKSSVKLFLSNC--- 261

Query: 226 VSPPLHTQ--CARVVLDFCTLLKKRVSSEDPLYGFCRSTFGSLLETARVYCADSEGDNVK 283
           V+ P + +  C  +VL+FC LL+K V  +  LY  CR+T GS+LET          DN  
Sbjct: 262 VALPKNQKNYCLPIVLEFCKLLRK-VCPDQKLYVTCRNTLGSMLETF---------DNPH 311

Query: 284 GSILVQ------EIFPFVSELAKSLLVDLDLSIDSPSNAGTFLINVADFTAFLVPLRARI 337
           G    Q      EIFPF +EL   LL +L        N+G    +    ++F   LR  I
Sbjct: 312 GVYNDQYETFGVEIFPFFTELTGLLLNEL------AQNSGPSFCDFQKVSSFWQQLRKVI 365

Query: 338 MEQQALRGSMPTQKRHKEALLVEEIEGLHLLYNDLLNKTDQCLQKLEQTWAGQGMMQGED 397
             + A    +P     +   L  EI  LH L+  LL   D C+ ++E + A + +   E 
Sbjct: 366 ELKVAF--PIPIVLPMQSTALEAEIRHLHRLFGSLLTTMDLCMCRVESSLADKEVGNSET 423

Query: 398 IYPAWSHYLSILKELYLISKLYDGAEEKLWKVLTRQRSVVCLLIVRYAKRTDEHQWILEH 457
           +  +WS YLSILK +  +S +Y GA+ +L  +L + +     L+V++AKR D+HQWI E+
Sbjct: 424 MSSSWSQYLSILKIINSMSNIYQGAKGQLAVMLNKNKVSFSALVVKFAKRGDDHQWIFEY 483

Query: 458 KCVTNFESRRHLAMMMFPEVKEDYEELHEMLIDRSQLLSESFEYIARADTASLHAGLFME 517
           K  TNFE+RRHLAM++FP+VKED+EE+HEMLIDRS LLSESFEYI  A   +LH GLFME
Sbjct: 484 KEATNFEARRHLAMLLFPDVKEDFEEMHEMLIDRSNLLSESFEYIVGASPEALHGGLFME 543

Query: 518 FKNEEATGPGVLREWFLLVCQALFNPQNALFVACPNDRRRFYPNHASKVHPLHLEYFGFS 577
           FKNEEATGPGVLREWF LVCQ +FNP+N LF+   +D RRF PN ASKV PLH ++F F+
Sbjct: 544 FKNEEATGPGVLREWFYLVCQEIFNPKNTLFLRSADDFRRFSPNPASKVDPLHPDFFEFT 603

Query: 578 GRVIALALMHKVQVGIVLDRVFFLQLAGKHITLEDVKDADPFLYSSCKQILEMDSDFIDS 637
           GRVIALALMHKVQVG++ DRVFFLQLAG  I+LED+KD D  +Y+SCKQILEMD +F DS
Sbjct: 604 GRVIALALMHKVQVGVLFDRVFFLQLAGLKISLEDIKDTDRIMYNSCKQILEMDPEFFDS 663

Query: 638 DA-LGLTFVREVEELGDTKVVELCPGGKNLIVNSKNREKYIDLLIKDRFVTSISEQVSHF 696
           +A LGLTFV E EELG    +ELCP GK   VNSKNR++Y+DLLI+ RF T I EQV  F
Sbjct: 664 NAGLGLTFVLETEELGKRDTIELCPDGKLKAVNSKNRKQYVDLLIERRFATPILEQVKQF 723

Query: 697 SKGFTDILSSSKFQQFFFQSLELEDLDWMLHGSEDTISVEDWKAHTEYNGYKETDIQITW 756
           S+GFTD+LS S   + FF+ L LEDLD ML G E+ IS++DWKAHTEYNG+KETD QI W
Sbjct: 724 SRGFTDMLSHSVPPRSFFKRLYLEDLDGMLRGGENPISIDDWKAHTEYNGFKETDRQIDW 783

Query: 757 FWEIVGRMTAEQRKVLLFFWTSVKYLPVEGFCGLASRLYIYKSPEPEDRLPSSHTCFYRM 816
           FW+I+ +MT E+++ +LFFWTS K++PVEGF GL+S+LYIY+  E  DRLP SHTCFYR+
Sbjct: 784 FWKILKKMTEEEQRSILFFWTSNKFVPVEGFRGLSSKLYIYRLYEANDRLPLSHTCFYRL 843

Query: 817 CFPAYSSMTVMQERLEVITQEHIGCSFGTW 846
           C P Y ++T+M++RL +I Q+H+  SFG W
Sbjct: 844 CIPRYPTITLMEQRLRLIAQDHVSSSFGKW 873


>pir||T07649 hypothetical protein T1P17.160 - Arabidopsis thaliana  (fragment)
          Length = 561

 Score =  362 bits (930), Expect = 2e-98
 Identities = 232/558 (41%), Positives = 316/558 (56%), Gaps = 60/558 (10%)

Query: 14  KRKHDEIDDDEGGVSD-IDPIRMKKDDA----AKAVYSAVHHRS---------------- 52
           KRK DE   D  GV++ ++ ++ ++ DA    A A  + +  RS                
Sbjct: 28  KRKRDEDSSDYVGVAESLEMLKKQEIDADHMAASAQQTLISWRSGENSRSLSSSGECSSS 87

Query: 53  -----IMLQFFVRMMGNGNTIVMQAHPDDTVQSIHERIQALKGIPVFEQRLIYNGKQLQS 107
                  LQ FVRMM  G TIV+ A   DTV+ +H+RI+    IP  EQR+IY GKQLQ 
Sbjct: 88  NRPESTRLQIFVRMMSGGKTIVIHAEKYDTVEKLHQRIEWKTKIPALEQRVIYKGKQLQR 147

Query: 108 EQTLAECSIGKDASLQLVGRMRSTGHPHAWQVINDMVSLVIRLCHNEPVHDANKTIKGLI 167
           E +L   SI +DASLQLV RM+ST HP AWQ I+D++  + R+   E   +    I   I
Sbjct: 148 ENSLTYYSIEQDASLQLVARMQSTEHPVAWQTIDDIMYTISRMYKGE---NLQSNINEKI 204

Query: 168 TSYLNLSPKNDNDSASGYFQIFMSAT--AVLVSLYLSPYTGNKDCADSSIRHFLTTCKTT 225
            ++  + P   ++S + Y  IF +++  A LV LY S    NK CA SS++ FL+ C   
Sbjct: 205 VTFFAMIPVESDESIAKYLNIFSNSSVPAALVMLYASSLERNKSCAKSSVKLFLSNC--- 261

Query: 226 VSPPLHTQ--CARVVLDFCTLLKKRVSSEDPLYGFCRSTFGSLLETARVYCADSEGDNVK 283
           V+ P + +  C  +VL+FC LL+K V  +  LY  CR+T GS+LET          DN  
Sbjct: 262 VALPKNQKNYCLPIVLEFCKLLRK-VCPDQKLYVTCRNTLGSMLETF---------DNPH 311

Query: 284 GSILVQ------EIFPFVSELAKSLLVDLDLSIDSPSNAGTFLINVADFTAFLVPLRARI 337
           G    Q      EIFPF +EL   LL +L        N+G    +    ++F   LR  I
Sbjct: 312 GVYNDQYETFGVEIFPFFTELTGLLLNEL------AQNSGPSFCDFQKVSSFWQQLRKVI 365

Query: 338 MEQQALRGSMPTQKRHKEALLVEEIEGLHLLYNDLLNKTDQCLQKLEQTWAGQGMMQGED 397
             + A    +P     +   L  EI  LH L+  LL   D C+ ++E + A + +   E 
Sbjct: 366 ELKVAF--PIPIVLPMQSTALEAEIRHLHRLFGSLLTTMDLCMCRVESSLADKEVGNSET 423

Query: 398 IYPAWSHYLSILKELYLISKLYDGAEEKLWKVLTRQRSVVCLLIVRYAKRTDEHQWILEH 457
           +  +WS YLSILK +  +S +Y GA+ +L  +L + +     L+V++AKR D+HQWI E+
Sbjct: 424 MSSSWSQYLSILKIINSMSNIYQGAKGQLAVMLNKNKVSFSALVVKFAKRGDDHQWIFEY 483

Query: 458 KCVTNFESRRHLAMMMFPEVKEDYEELHEMLIDRSQLLSESFEYIARADTASLHAGLFME 517
           K  TNFE+RRHLAM++FP+VKED+EE+HEMLIDRS LLSESFEYI  A   +LH GLFME
Sbjct: 484 KEATNFEARRHLAMLLFPDVKEDFEEMHEMLIDRSNLLSESFEYIVGASPEALHGGLFME 543

Query: 518 FKNEEATGPGVLREWFLL 535
           FKNEEATGPGVLREWF L
Sbjct: 544 FKNEEATGPGVLREWFYL 561


>gb|EAA65131.1| hypothetical protein AN1966.2 [Aspergillus nidulans FGSC A4]
            gi|67523019|ref|XP_659570.1| hypothetical protein
            AN1966_2 [Aspergillus nidulans FGSC A4]
            gi|49088592|ref|XP_406103.1| hypothetical protein
            AN1966.2 [Aspergillus nidulans FGSC A4]
          Length = 4022

 Score =  204 bits (519), Expect = 1e-50
 Identities = 120/355 (33%), Positives = 188/355 (52%), Gaps = 17/355 (4%)

Query: 486  EMLIDRSQLLSESFEYIARADTASL-HAGLFMEFKNEEATGPG-VLREWFLLVCQALFNP 543
            ++ + R Q+  +SF  +       L H  L + F  EE    G V REWF ++ + +FNP
Sbjct: 3666 QLAVRRDQVFLDSFRALYFKSAEELKHGKLNVRFHGEEGVDAGGVTREWFQVLARGMFNP 3725

Query: 544  QNALFVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQL 603
              ALF+    DR  F+PN  S V+P HL +F F GR+I  AL     +     R  +  +
Sbjct: 3726 DYALFIPVAADRTTFHPNRLSGVNPEHLMFFKFIGRIIGKALYEGRVLDCHFSRAVYKCI 3785

Query: 604  AGKHITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGG 663
             G++++++D++  D   Y S   +LE D     +D +  TF  E ++ G+ + ++L   G
Sbjct: 3786 LGRNVSIKDMETLDLDYYKSLLWMLENDI----TDIITETFAVETDDFGEKQTIDLIENG 3841

Query: 664  KNLIVNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLD 723
            +N+ V  +N+E+Y+  ++  R V S+ EQ+ +F KGF +I+       F  Q LEL    
Sbjct: 3842 RNIPVTQENKEEYVQKVVDYRLVASVREQLDNFLKGFHEIIPPELISIFNEQELEL---- 3897

Query: 724  WMLHGSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLP 783
             ++ G  + I V+DWKA+TEY+ Y  +  QI WFW  V     E+R  LL F T    +P
Sbjct: 3898 -LISGLPE-IDVDDWKANTEYHNYSASSPQIQWFWRAVRSFDKEERAKLLQFVTGTSKVP 3955

Query: 784  VEGFCGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEV 833
            + GF  L      SR  I++    +DRLPSSHTCF ++  P Y S   +++RL +
Sbjct: 3956 LNGFKELEGMNGVSRFNIHRDYGNKDRLPSSHTCFNQLDLPEYDSYETLRQRLYI 4010


>gb|EAK84580.1| hypothetical protein UM03442.1 [Ustilago maydis 521]
           gi|49073738|ref|XP_401057.1| hypothetical protein
           UM03442.1 [Ustilago maydis 521]
          Length = 571

 Score =  204 bits (519), Expect = 1e-50
 Identities = 125/385 (32%), Positives = 196/385 (50%), Gaps = 18/385 (4%)

Query: 460 VTNFESRRHLAMMMFPEVKEDYEELHEMLIDRSQLLSESFEYIARADTASL-HAGLFMEF 518
           V +F+++++       + + D+     + + R+ +  +SF Y +R     + H  L + F
Sbjct: 190 VLDFDNKKNYFTQQLHKGRRDHYTPLSLSVRRNSVFEDSFRYFSRKTGPEVKHGKLNVRF 249

Query: 519 KNEEATGPG-VLREWFLLVCQALFNPQNALFVACPNDRRRFYPNHASKVHPLHLEYFGFS 577
            NEE    G V REWF ++ +A+FNP  ALF  C  DR  + PN  S V+P HL +F F 
Sbjct: 250 TNEEGIDAGGVTREWFQVLARAMFNPDYALFQPCAADRTTYQPNRMSYVNPDHLSFFKFV 309

Query: 578 GRVIALALMHKVQVGIVLDRVFFLQLAGKHITLEDVKDADPFLYSSCKQILEMDSDFIDS 637
           GR+I  A+     +     R F+  + GK +   D++  DP  + S + +L  D     +
Sbjct: 310 GRIIGKAIYDGRLLDAYFTRSFYKHILGKPVDYRDLESIDPEYFKSLEWMLSNDI----T 365

Query: 638 DALGLTFVREVEELGDTKVVELCPGGKNLIVNSKNREKYIDLLIKDRFVTSISEQVSHFS 697
           D L LTF  + EE G+TKVV+L P G ++ V   N+++Y+ L+ + R   SI  Q+  F 
Sbjct: 366 DILDLTFSVDDEEFGETKVVDLKPNGTSISVTEANKQEYVRLVTEQRLTKSIKSQIDAFL 425

Query: 698 KGFTDILSSSKFQQFFFQSLELEDLDWMLHGSEDTISVEDWKAHTEYNGYKETDIQITWF 757
            GF +I+ S   + F  Q LEL     ++ G  D I V+ WK +TE +GY   D  + W+
Sbjct: 426 GGFNEIIPSDLIRIFSEQELEL-----LISGLPD-IDVDAWKNNTELHGYSSGDAVVQWW 479

Query: 758 WEIVGRMTAEQRKVLLFFWTSVKYLPVEGFCGL-----ASRLYIYKSPEPEDRLPSSHTC 812
           W  V      ++  LL F T    +P+EGF  L       R  I+K+    DRLP++HTC
Sbjct: 480 WRAVRSFDQTEKAKLLQFITGTSKVPLEGFAHLQGVQGTQRFNIHKA-YGADRLPAAHTC 538

Query: 813 FYRMCFPAYSSMTVMQERLEVITQE 837
           F ++  P Y S   ++  L +   E
Sbjct: 539 FNQLDLPQYESYEKLRSSLLLAMNE 563


>gb|EAA51657.1| hypothetical protein MG03252.4 [Magnaporthe grisea 70-15]
            gi|39942344|ref|XP_360709.1| hypothetical protein
            MG03252.4 [Magnaporthe grisea 70-15]
          Length = 4048

 Score =  202 bits (513), Expect = 5e-50
 Identities = 118/353 (33%), Positives = 188/353 (52%), Gaps = 17/353 (4%)

Query: 486  EMLIDRSQLLSESFEYIARADTASLHAG-LFMEFKNEEATGPG-VLREWFLLVCQALFNP 543
            ++ + R  +  +SF+ +       +  G L + F  EE    G V REWF ++ + +F+P
Sbjct: 3692 QLSVRRDHVFHDSFKSLYFKKGEEMKYGKLNIRFHGEEGVDAGGVTREWFQVLSRQMFDP 3751

Query: 544  QNALFVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQL 603
               LF    +DR  F+PN  S ++  HL +F F GR+I  AL     +     R  + ++
Sbjct: 3752 NYVLFTPVSSDRTTFHPNKLSSINDEHLMFFKFIGRIIGKALYEGRVLDCYFSRAVYKRI 3811

Query: 604  AGKHITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGG 663
             GK ++++D++  DP  Y S   +LE D     +D +  TF  E +  G TK V+LC  G
Sbjct: 3812 LGKPVSVKDMESFDPEYYKSLVWMLENDI----TDIITETFAVEDDAFGVTKTVDLCENG 3867

Query: 664  KNLIVNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLD 723
            +N+ V   N+ +Y+ L+++ + + S+ +Q++ F +GF DI+ +     F  Q LEL    
Sbjct: 3868 RNIPVTEDNKHEYVRLVVEHKLLASVKDQMAEFLQGFHDIIPAELIAIFNEQELEL---- 3923

Query: 724  WMLHGSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLP 783
             ++ G  D I V+DWKAHTEY+ Y+ +  QI WFW  V     E+R  LL F T    +P
Sbjct: 3924 -LISGLPD-IDVDDWKAHTEYHNYQPSSQQIQWFWRAVRSFDKEERAKLLQFVTGTSKVP 3981

Query: 784  VEGFCGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERL 831
            + GF  L      SR  I++     DRLPSSHTCF ++  P Y S  V+++++
Sbjct: 3982 LNGFKELEGMNGVSRFNIHRDYGRPDRLPSSHTCFNQLDLPEYESYDVLRKQI 4034


>gb|EAL89711.1| ubiquitin-protein ligase (Tom1), putative [Aspergillus fumigatus
            Af293]
          Length = 4037

 Score =  199 bits (507), Expect = 2e-49
 Identities = 120/354 (33%), Positives = 188/354 (52%), Gaps = 19/354 (5%)

Query: 486  EMLIDRSQLLSESFE--YIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFN 542
            ++ + R Q+  +SF+  Y   AD    +  L + F  EE    G V REWF ++ + +FN
Sbjct: 3681 QLSVRRDQVFLDSFKSLYFKTADELK-YGKLNVRFHGEEGVDAGGVTREWFQVLARGMFN 3739

Query: 543  PQNALFVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQ 602
            P  ALF+    DR  F+PN  S V+  HL +F F GR+I  AL     +     R  +  
Sbjct: 3740 PNYALFIPVAADRTTFHPNRLSGVNSEHLMFFKFIGRIIGKALYEGRVLDCHFSRAVYKC 3799

Query: 603  LAGKHITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPG 662
            + G+ ++++D++  D   Y S   +LE D     +D +  TF  E ++ G+ +V++L   
Sbjct: 3800 ILGRSVSIKDMETLDLDYYKSLLWMLENDI----TDIITETFAVETDDFGEKQVIDLIEN 3855

Query: 663  GKNLIVNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDL 722
            G+N+ V  +N+E+Y+  ++  R V S+ +Q+ +F KGF DI+       F  Q LEL   
Sbjct: 3856 GRNIPVTQENKEEYVQRVVDYRLVKSVKDQLDNFLKGFHDIIPPDLISIFNEQELEL--- 3912

Query: 723  DWMLHGSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYL 782
              ++ G  + I V+DWKA+TEY+ Y  +  QI WFW  V     E+R  LL F T    +
Sbjct: 3913 --LISGLPE-IDVDDWKANTEYHNYSASSPQIQWFWRAVRSFDKEERAKLLQFVTGTSKV 3969

Query: 783  PVEGFCGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERL 831
            P+ GF  L      S+  I++    +DRLPSSHTCF ++  P Y S   +++RL
Sbjct: 3970 PLNGFKELEGMNGVSKFNIHRDYGNKDRLPSSHTCFNQLDLPEYDSYETLRQRL 4023


>emb|CAB55856.1| SPAC1805.15c [Schizosaccharomyces pombe]
           gi|19114838|ref|NP_593926.1| hypothetical protein
           SPAC1805.15c [Schizosaccharomyces pombe 972h-]
           gi|46397059|sp|Q9UTG2|PUB2_SCHPO E3 ubiquitin--protein
           ligase pub2
          Length = 671

 Score =  199 bits (506), Expect = 3e-49
 Identities = 124/390 (31%), Positives = 202/390 (51%), Gaps = 19/390 (4%)

Query: 462 NFESRRHLAMMMF-PEVKEDYEELHEMLIDRSQLLSESFEYIARADTASLHAGLFMEFKN 520
           N E +R +A M   PE+  +  +L ++ + R+    ++++ I++   + +   L + F+N
Sbjct: 294 NDEYQRKIAYMYDRPEMAVNDAQL-QLKVSRATTFEDAYDIISKLSVSDMKKKLLIRFRN 352

Query: 521 EEATG-PGVLREWFLLVCQALFNPQNALFVACPNDRRRFYPNHASKVHPLHLEYFGFSGR 579
           E+     GV RE+F ++  A+FNP  +LF    +D      +  S V+P    YF F GR
Sbjct: 353 EDGLDYGGVSREFFYILSHAIFNPGYSLFEYATDDNYGLQISPLSSVNPDFRSYFRFVGR 412

Query: 580 VIALALMHKVQVGIVLDRVFFLQLAGKHITLEDVKDADPFLYSSCKQILEMDSDFIDSDA 639
           V+ LA+ H+  + +     F+ ++  K + LEDVKD D   Y S K I   D D    ++
Sbjct: 413 VMGLAIYHRRYLDVQFVLPFYKRILQKPLCLEDVKDVDEVYYESLKWIKNNDVD----ES 468

Query: 640 LGLTFVREVEELGDTKVVELCPGGKNLIVNSKNREKYIDLLIKDRFVTSISEQVSHFSKG 699
           L L F  E    G++  V+L P G+N+ VN++N+  Y+  L + + VTS  EQ +    G
Sbjct: 469 LCLNFSVEENRFGESVTVDLIPNGRNIAVNNQNKMNYLKALTEHKLVTSTEEQFNALKGG 528

Query: 700 FTDILSSSKFQQFFFQSLELEDLDWMLHGSEDTISVEDWKAHTEYNGYKETDIQITWFWE 759
             +++  S  Q F        +LD +L+G  D I V+DWK  T+Y  Y ETD  + WFWE
Sbjct: 529 LNELIPDSVLQIF-----NENELDTLLNGKRD-IDVQDWKRFTDYRSYTETDDIVIWFWE 582

Query: 760 IVGRMTAEQRKVLLFFWTSVKYLPVEGFCGL----ASRLYIYKSPEPEDRLPSSHTCFYR 815
           ++   + E++  LL F T    LP+ GF  +      R +  +      +LP +HTCF R
Sbjct: 583 LLSEWSPEKKAKLLQFATGTSRLPLSGFKDMHGSDGPRKFTIEKVGHISQLPKAHTCFNR 642

Query: 816 MCFPAYSSMTVMQERLEVITQEHIGCSFGT 845
           +  P Y+S   ++++L +  QE  G  FGT
Sbjct: 643 LDIPPYNSKEELEQKLTIAIQETAG--FGT 670


>gb|AAX79795.1| ubiquitin-protein ligase, putative [Trypanosoma brucei]
          Length = 4304

 Score =  199 bits (505), Expect = 4e-49
 Identities = 122/353 (34%), Positives = 185/353 (51%), Gaps = 23/353 (6%)

Query: 489  IDRSQLLSESFEYIARADTASLHAGLFMEFKNEE-ATGPGVLREWFLLVCQALFNPQNAL 547
            I+R Q L +SF  +++ +  + H  + + F  EE A   G+ REWF L+ + + N   AL
Sbjct: 3955 INRGQCLRDSFAQLSKLN--NFHGSISVRFSGEEGADAGGLTREWFQLIAEEMVNDNYAL 4012

Query: 548  FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
            F+    +   + PN  S V+PLHL+YF F+G V+ +A+ H+V + +   R  +  + G  
Sbjct: 4013 FIHS-REGMTYQPNPLSGVNPLHLQYFRFAGIVVGMAVAHRVAIDVHFTRAVYRHMIGIQ 4071

Query: 608  ITLEDVKDADPFLYSSCKQILEMD-SDFIDSDALGLTFVREVEELGDTKVVELCPGGKNL 666
             T  D+K  DP LY + K +L  D SD      LGL F    E+ G T+ VEL P G  +
Sbjct: 4072 PTFGDLKSVDPELYENLKWLLVNDVSD------LGLFFTVSCEKFGVTEEVELIPNGSQV 4125

Query: 667  IVNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWML 726
             V + N+ +Y+ L  +      I EQ+  F KGF  ++   + + F  Q LEL     ++
Sbjct: 4126 AVTNANKSQYVRLRCEFCMTRQIEEQLQEFLKGFYAVIPRKEIRNFSAQELEL-----VI 4180

Query: 727  HGSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEG 786
             G  D I VED + +T Y+GY  T +QI WFWE+V  M+ E R  LL F T    +P  G
Sbjct: 4181 CGMPD-IDVEDLRLNTTYDGYTSTSLQIRWFWEVVAAMSKEDRANLLQFATGASRVPHGG 4239

Query: 787  FCGLAS------RLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEV 833
            F  L S      R  + +  +  + LP +HTCF ++  P YSS   ++++L V
Sbjct: 4240 FSNLESSNGSPQRFTVSRWADSAELLPQAHTCFNKIALPEYSSCEELRKKLMV 4292


>gb|EAA65522.1| hypothetical protein AN1339.2 [Aspergillus nidulans FGSC A4]
           gi|67521764|ref|XP_658943.1| hypothetical protein
           AN1339_2 [Aspergillus nidulans FGSC A4]
           gi|49086950|ref|XP_405476.1| hypothetical protein
           AN1339.2 [Aspergillus nidulans FGSC A4]
          Length = 821

 Score =  196 bits (497), Expect = 4e-48
 Identities = 120/358 (33%), Positives = 187/358 (51%), Gaps = 17/358 (4%)

Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPGVL-REWFLLVCQALFNPQNAL 547
           + R+ +  +S+  I R   + L   L ++F  E+    G L RE+F L+   +FNP   L
Sbjct: 471 VRRNNIFEDSYAEIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCL 530

Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
           F    +D      N  S V+P HL YF F GRV+ LA+ H+  +       F+  +  K 
Sbjct: 531 FEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKK 590

Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
           ++L+D++  D  L+ +    LE D + I    + LTF  + E+ G+ + +EL PGG+++ 
Sbjct: 591 VSLQDMEGVDEDLHRNLTWTLENDIEGI----IDLTFTVDDEKFGERRTIELKPGGEDIP 646

Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
           V ++N+ +Y++L+ + + V  + EQ + F  GF +++ +     F  + LEL      L 
Sbjct: 647 VTNENKHEYVELVTEWKIVKRVEEQFNAFMSGFNELIPADLVNVFDERELEL------LI 700

Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
           G    I V+DWK HT+Y GY+E D  I  FW+IV    AEQ+  LL F T    +PV GF
Sbjct: 701 GGIADIDVDDWKKHTDYRGYQEQDEVIQNFWKIVRTWDAEQKSRLLQFTTGTSRIPVNGF 760

Query: 788 CGLAS-----RLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIG 840
             L       R  I KS +P   LP SHTCF R+  P Y S  V++ +L +  +E +G
Sbjct: 761 KDLQGSDGPRRFTIEKSGDP-IALPKSHTCFNRLDLPPYKSHEVLEHKLSIAVEETLG 817


>ref|NP_067498.3| HECT, UBA and WWE domain containing 1 [Mus musculus]
          Length = 4378

 Score =  195 bits (495), Expect = 6e-48
 Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)

Query: 489  IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
            + R  +  +S+  + R     +   L++ F+ EE    G +LREW++++ + +FNP  AL
Sbjct: 4025 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 4084

Query: 548  FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
            F   P DR  +  N +S  +P HL YF F GR++A A+     +     R F+  + GK 
Sbjct: 4085 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 4144

Query: 608  ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
            +   D++  D   Y     +LE D   +  D   LTF  EV+E G  +V +L P G N++
Sbjct: 4145 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 4201

Query: 668  VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
            V  +N+++Y+ L+ + R   +I +Q++ F +GF +I+       F  Q LEL      L 
Sbjct: 4202 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 4255

Query: 728  GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
                TI ++D K++TEY+ Y+   IQI WFW  +       R   L F T    +P++GF
Sbjct: 4256 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 4315

Query: 788  CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
              L       +  I++     DRLPS+HTCF ++  PAY S   ++  L +  QE   CS
Sbjct: 4316 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 4372

Query: 843  FG 844
             G
Sbjct: 4373 EG 4374


>ref|XP_576948.1| PREDICTED: similar to mKIAA0312 protein [Rattus norvegicus]
          Length = 4147

 Score =  195 bits (495), Expect = 6e-48
 Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)

Query: 489  IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
            + R  +  +S+  + R     +   L++ F+ EE    G +LREW++++ + +FNP  AL
Sbjct: 3794 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 3853

Query: 548  FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
            F   P DR  +  N +S  +P HL YF F GR++A A+     +     R F+  + GK 
Sbjct: 3854 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 3913

Query: 608  ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
            +   D++  D   Y     +LE D   +  D   LTF  EV+E G  +V +L P G N++
Sbjct: 3914 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 3970

Query: 668  VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
            V  +N+++Y+ L+ + R   +I +Q++ F +GF +I+       F  Q LEL      L 
Sbjct: 3971 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 4024

Query: 728  GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
                TI ++D K++TEY+ Y+   IQI WFW  +       R   L F T    +P++GF
Sbjct: 4025 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 4084

Query: 788  CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
              L       +  I++     DRLPS+HTCF ++  PAY S   ++  L +  QE   CS
Sbjct: 4085 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 4141

Query: 843  FG 844
             G
Sbjct: 4142 EG 4143


>emb|CAI42354.1| upstream regulatory element binding protein 1 (UREB1) [Homo sapiens]
            gi|57210033|emb|CAI42654.1| upstream regulatory element
            binding protein 1 (UREB1) [Homo sapiens]
            gi|57160758|emb|CAI39580.1| upstream regulatory element
            binding protein 1 (UREB1) [Homo sapiens]
            gi|60549639|gb|AAX24125.1| LASU1 [Homo sapiens]
            gi|61676188|ref|NP_113584.3| HECT, UBA and WWE domain
            containing 1 [Homo sapiens]
          Length = 4374

 Score =  195 bits (495), Expect = 6e-48
 Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)

Query: 489  IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
            + R  +  +S+  + R     +   L++ F+ EE    G +LREW++++ + +FNP  AL
Sbjct: 4021 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 4080

Query: 548  FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
            F   P DR  +  N +S  +P HL YF F GR++A A+     +     R F+  + GK 
Sbjct: 4081 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 4140

Query: 608  ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
            +   D++  D   Y     +LE D   +  D   LTF  EV+E G  +V +L P G N++
Sbjct: 4141 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 4197

Query: 668  VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
            V  +N+++Y+ L+ + R   +I +Q++ F +GF +I+       F  Q LEL      L 
Sbjct: 4198 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 4251

Query: 728  GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
                TI ++D K++TEY+ Y+   IQI WFW  +       R   L F T    +P++GF
Sbjct: 4252 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 4311

Query: 788  CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
              L       +  I++     DRLPS+HTCF ++  PAY S   ++  L +  QE   CS
Sbjct: 4312 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 4368

Query: 843  FG 844
             G
Sbjct: 4369 EG 4370


>emb|CAI42656.1| upstream regulatory element binding protein 1 (UREB1) [Homo sapiens]
            gi|57160759|emb|CAI39581.1| upstream regulatory element
            binding protein 1 (UREB1) [Homo sapiens]
          Length = 3407

 Score =  195 bits (495), Expect = 6e-48
 Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)

Query: 489  IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
            + R  +  +S+  + R     +   L++ F+ EE    G +LREW++++ + +FNP  AL
Sbjct: 3054 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 3113

Query: 548  FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
            F   P DR  +  N +S  +P HL YF F GR++A A+     +     R F+  + GK 
Sbjct: 3114 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 3173

Query: 608  ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
            +   D++  D   Y     +LE D   +  D   LTF  EV+E G  +V +L P G N++
Sbjct: 3174 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 3230

Query: 668  VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
            V  +N+++Y+ L+ + R   +I +Q++ F +GF +I+       F  Q LEL      L 
Sbjct: 3231 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 3284

Query: 728  GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
                TI ++D K++TEY+ Y+   IQI WFW  +       R   L F T    +P++GF
Sbjct: 3285 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 3344

Query: 788  CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
              L       +  I++     DRLPS+HTCF ++  PAY S   ++  L +  QE   CS
Sbjct: 3345 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 3401

Query: 843  FG 844
             G
Sbjct: 3402 EG 3403


>emb|CAI42644.1| upstream regulatory element binding protein 1 (UREB1) [Homo sapiens]
            gi|57160756|emb|CAI39578.1| upstream regulatory element
            binding protein 1 (UREB1) [Homo sapiens]
          Length = 1196

 Score =  195 bits (495), Expect = 6e-48
 Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)

Query: 489  IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
            + R  +  +S+  + R     +   L++ F+ EE    G +LREW++++ + +FNP  AL
Sbjct: 843  VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 902

Query: 548  FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
            F   P DR  +  N +S  +P HL YF F GR++A A+     +     R F+  + GK 
Sbjct: 903  FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 962

Query: 608  ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
            +   D++  D   Y     +LE D   +  D   LTF  EV+E G  +V +L P G N++
Sbjct: 963  VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 1019

Query: 668  VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
            V  +N+++Y+ L+ + R   +I +Q++ F +GF +I+       F  Q LEL      L 
Sbjct: 1020 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 1073

Query: 728  GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
                TI ++D K++TEY+ Y+   IQI WFW  +       R   L F T    +P++GF
Sbjct: 1074 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 1133

Query: 788  CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
              L       +  I++     DRLPS+HTCF ++  PAY S   ++  L +  QE   CS
Sbjct: 1134 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 1190

Query: 843  FG 844
             G
Sbjct: 1191 EG 1192


>ref|XP_538052.1| PREDICTED: similar to E3 ubiquitin protein ligase URE-B1 (HSPC272)
            [Canis familiaris]
          Length = 4405

 Score =  195 bits (495), Expect = 6e-48
 Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)

Query: 489  IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
            + R  +  +S+  + R     +   L++ F+ EE    G +LREW++++ + +FNP  AL
Sbjct: 4052 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 4111

Query: 548  FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
            F   P DR  +  N +S  +P HL YF F GR++A A+     +     R F+  + GK 
Sbjct: 4112 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 4171

Query: 608  ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
            +   D++  D   Y     +LE D   +  D   LTF  EV+E G  +V +L P G N++
Sbjct: 4172 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 4228

Query: 668  VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
            V  +N+++Y+ L+ + R   +I +Q++ F +GF +I+       F  Q LEL      L 
Sbjct: 4229 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 4282

Query: 728  GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
                TI ++D K++TEY+ Y+   IQI WFW  +       R   L F T    +P++GF
Sbjct: 4283 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 4342

Query: 788  CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
              L       +  I++     DRLPS+HTCF ++  PAY S   ++  L +  QE   CS
Sbjct: 4343 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 4399

Query: 843  FG 844
             G
Sbjct: 4400 EG 4401


>dbj|BAA20771.2| KIAA0312 [Homo sapiens]
          Length = 3192

 Score =  195 bits (495), Expect = 6e-48
 Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)

Query: 489  IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
            + R  +  +S+  + R     +   L++ F+ EE    G +LREW++++ + +FNP  AL
Sbjct: 2839 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 2898

Query: 548  FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
            F   P DR  +  N +S  +P HL YF F GR++A A+     +     R F+  + GK 
Sbjct: 2899 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 2958

Query: 608  ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
            +   D++  D   Y     +LE D   +  D   LTF  EV+E G  +V +L P G N++
Sbjct: 2959 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 3015

Query: 668  VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
            V  +N+++Y+ L+ + R   +I +Q++ F +GF +I+       F  Q LEL      L 
Sbjct: 3016 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 3069

Query: 728  GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
                TI ++D K++TEY+ Y+   IQI WFW  +       R   L F T    +P++GF
Sbjct: 3070 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 3129

Query: 788  CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
              L       +  I++     DRLPS+HTCF ++  PAY S   ++  L +  QE   CS
Sbjct: 3130 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 3186

Query: 843  FG 844
             G
Sbjct: 3187 EG 3188


>gb|AAX24124.1| LASU1 [Mus musculus]
          Length = 4377

 Score =  195 bits (495), Expect = 6e-48
 Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)

Query: 489  IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
            + R  +  +S+  + R     +   L++ F+ EE    G +LREW++++ + +FNP  AL
Sbjct: 4024 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 4083

Query: 548  FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
            F   P DR  +  N +S  +P HL YF F GR++A A+     +     R F+  + GK 
Sbjct: 4084 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 4143

Query: 608  ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
            +   D++  D   Y     +LE D   +  D   LTF  EV+E G  +V +L P G N++
Sbjct: 4144 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 4200

Query: 668  VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
            V  +N+++Y+ L+ + R   +I +Q++ F +GF +I+       F  Q LEL      L 
Sbjct: 4201 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 4254

Query: 728  GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
                TI ++D K++TEY+ Y+   IQI WFW  +       R   L F T    +P++GF
Sbjct: 4255 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 4314

Query: 788  CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
              L       +  I++     DRLPS+HTCF ++  PAY S   ++  L +  QE   CS
Sbjct: 4315 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 4371

Query: 843  FG 844
             G
Sbjct: 4372 EG 4373


>gb|AAH63505.1| HUWE1 protein [Homo sapiens]
          Length = 388

 Score =  195 bits (495), Expect = 6e-48
 Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)

Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
           + R  +  +S+  + R     +   L++ F+ EE    G +LREW++++ + +FNP  AL
Sbjct: 35  VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 94

Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
           F   P DR  +  N +S  +P HL YF F GR++A A+     +     R F+  + GK 
Sbjct: 95  FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 154

Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
           +   D++  D   Y     +LE D   +  D   LTF  EV+E G  +V +L P G N++
Sbjct: 155 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 211

Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
           V  +N+++Y+ L+ + R   +I +Q++ F +GF +I+       F  Q LEL      L 
Sbjct: 212 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 265

Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
               TI ++D K++TEY+ Y+   IQI WFW  +       R   L F T    +P++GF
Sbjct: 266 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 325

Query: 788 CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
             L       +  I++     DRLPS+HTCF ++  PAY S   ++  L +  QE   CS
Sbjct: 326 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 382

Query: 843 FG 844
            G
Sbjct: 383 EG 384


>gb|AAH54372.1| Huwe1 protein [Mus musculus]
          Length = 444

 Score =  195 bits (495), Expect = 6e-48
 Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)

Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
           + R  +  +S+  + R     +   L++ F+ EE    G +LREW++++ + +FNP  AL
Sbjct: 91  VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 150

Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
           F   P DR  +  N +S  +P HL YF F GR++A A+     +     R F+  + GK 
Sbjct: 151 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 210

Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
           +   D++  D   Y     +LE D   +  D   LTF  EV+E G  +V +L P G N++
Sbjct: 211 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 267

Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
           V  +N+++Y+ L+ + R   +I +Q++ F +GF +I+       F  Q LEL      L 
Sbjct: 268 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 321

Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
               TI ++D K++TEY+ Y+   IQI WFW  +       R   L F T    +P++GF
Sbjct: 322 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 381

Query: 788 CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
             L       +  I++     DRLPS+HTCF ++  PAY S   ++  L +  QE   CS
Sbjct: 382 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 438

Query: 843 FG 844
            G
Sbjct: 439 EG 440


>gb|AAH11391.1| Huwe1 protein [Mus musculus]
          Length = 1080

 Score =  195 bits (495), Expect = 6e-48
 Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)

Query: 489  IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
            + R  +  +S+  + R     +   L++ F+ EE    G +LREW++++ + +FNP  AL
Sbjct: 727  VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 786

Query: 548  FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
            F   P DR  +  N +S  +P HL YF F GR++A A+     +     R F+  + GK 
Sbjct: 787  FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 846

Query: 608  ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
            +   D++  D   Y     +LE D   +  D   LTF  EV+E G  +V +L P G N++
Sbjct: 847  VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 903

Query: 668  VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
            V  +N+++Y+ L+ + R   +I +Q++ F +GF +I+       F  Q LEL      L 
Sbjct: 904  VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 957

Query: 728  GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
                TI ++D K++TEY+ Y+   IQI WFW  +       R   L F T    +P++GF
Sbjct: 958  SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 1017

Query: 788  CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
              L       +  I++     DRLPS+HTCF ++  PAY S   ++  L +  QE   CS
Sbjct: 1018 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 1074

Query: 843  FG 844
             G
Sbjct: 1075 EG 1076


  Database: nr
    Posted date:  Jul 5, 2005 12:34 AM
  Number of letters in database: 863,360,394
  Number of sequences in database:  2,540,612
  
Lambda     K      H
   0.322    0.137    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,419,820,630
Number of Sequences: 2540612
Number of extensions: 59328446
Number of successful extensions: 138811
Number of sequences better than 10.0: 1719
Number of HSP's better than 10.0 without gapping: 1488
Number of HSP's successfully gapped in prelim test: 232
Number of HSP's that attempted gapping in prelim test: 133795
Number of HSP's gapped (non-prelim): 3128
length of query: 846
length of database: 863,360,394
effective HSP length: 137
effective length of query: 709
effective length of database: 515,296,550
effective search space: 365345253950
effective search space used: 365345253950
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 80 (35.4 bits)


Lotus: description of TM0288.8