BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0237.14
(1754 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
dbj|BAB09828.1| unnamed protein product [Arabidopsis thaliana] g... 1921 0.0
ref|XP_474331.1| OSJNBa0018M05.18 [Oryza sativa (japonica cultiv... 1581 0.0
emb|CAG09278.1| unnamed protein product [Tetraodon nigroviridis] 146 5e-33
ref|XP_417138.1| PREDICTED: similar to sacsin [Gallus gallus] 136 7e-30
ref|XP_534533.1| PREDICTED: similar to sacsin [Canis familiaris] 130 5e-28
emb|CAG02848.1| unnamed protein product [Tetraodon nigroviridis] 130 5e-28
gb|AAF31262.1| sacsin [Homo sapiens] gi|13124523|sp|Q9NZJ4|SACS_... 129 7e-28
emb|CAI13923.1| spastic ataxia of Charlevoix-Saguenay (sacsin) [... 129 7e-28
ref|NP_055178.2| sacsin [Homo sapiens] 129 7e-28
ref|XP_224256.3| PREDICTED: similar to sacsin [Rattus norvegicus] 128 2e-27
ref|NP_056603.1| sacsin [Mus musculus] gi|6907044|gb|AAF31263.1|... 128 2e-27
ref|XP_586753.1| PREDICTED: similar to sacsin, partial [Bos taurus] 128 2e-27
emb|CAE45964.1| hypothetical protein [Homo sapiens] 79 1e-12
ref|XP_595962.1| PREDICTED: similar to spastic ataxia of Charlev... 74 6e-11
dbj|BAC30083.1| unnamed protein product [Mus musculus] 66 1e-08
ref|XP_647016.1| hypothetical protein DDB0190084 [Dictyostelium ... 59 2e-06
ref|NP_766397.1| hypothetical protein LOC239128 [Mus musculus] g... 54 5e-05
ref|XP_647014.1| hypothetical protein DDB0190082 [Dictyostelium ... 51 3e-04
ref|XP_647015.1| hypothetical protein DDB0190083 [Dictyostelium ... 50 0.001
dbj|BAD32289.1| mKIAA0730 protein [Mus musculus] 45 0.022
>dbj|BAB09828.1| unnamed protein product [Arabidopsis thaliana]
gi|15237223|ref|NP_197702.1| zinc finger (C3HC4-type RING
finger) family protein [Arabidopsis thaliana]
Length = 4706
Score = 1921 bits (4977), Expect = 0.0
Identities = 973/1810 (53%), Positives = 1276/1810 (69%), Gaps = 101/1810 (5%)
Query: 1 LYDPRVPELKKMLHGDVFFPSDKFLDPEILDTLVCLGLRTTLGFTGLLDCARSVSLLHDS 60
LYDPRVP L+++LH +V+FPS+KF D +ILD LV LGLRTTL + LD ARSVS+LHD
Sbjct: 2342 LYDPRVPALQELLHKEVYFPSEKFSDSKILDALVGLGLRTTLDCSTYLDAARSVSMLHDL 2401
Query: 61 GDTEASKHGKGLLVFLDKLACKLSSNGESENDDQSLAVRSNITMDDAVVYDGFPKDENSL 120
GD EAS++G+ LL + L+ KLSS N D+S + S IT +D+ + +P+ E
Sbjct: 2402 GDLEASRYGRRLLFHIKTLSIKLSSKTGEANHDESQNIMS-ITSEDSFDGETYPEYETET 2460
Query: 121 IDDVDLFMSSLINDMVEEEFWSELKLITWCPVILDPAVRGLPWLKSSKQVALPTVVRPKS 180
++ SL+ E+EFW +L+ I WCP+ LDP + G+PWL+SS VA P VRPKS
Sbjct: 2461 S-----YLGSLLTQQSEDEFWCQLRSIPWCPICLDPPIEGIPWLESSNLVASPDRVRPKS 2515
Query: 181 QMWLVSSSMLILDGECGTTYLQTKLGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDF 240
QM+LVS++M +LDGEC ++YL KLGWMDC I +L RQLIE+SKSY++ K+ S ++P+F
Sbjct: 2516 QMFLVSATMHLLDGECQSSYLHQKLGWMDCLTIDILCRQLIEISKSYKEQKSRSSVNPEF 2575
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDFVSPNALAFDSPVKFTPY 300
+ LQ +IP LY++LQE +DF LK+ L GV WVW+GDDFVS + L+FDSPVKFTPY
Sbjct: 2576 ESMLQSQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDFVSADVLSFDSPVKFTPY 2635
Query: 301 LYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCVHEAI 360
LYVV SELS++K+L+++LGVRLSF DY++ LQ LQND+ G L+ +Q+NFV CV EA+
Sbjct: 2636 LYVVPSELSDFKELLLELGVRLSFDAADYMNTLQHLQNDIKGSQLTDEQINFVLCVLEAV 2695
Query: 361 AECCLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSLIGRHFVHPSISNDLA 420
A+C E +S L +PD+ G L+ DLVYNDAPW+++SSL G+ FVHPSI++D+A
Sbjct: 2696 ADCFSEVSSDSDNNSVL-VPDSAGFLVPLEDLVYNDAPWVDSSSLSGKRFVHPSINSDMA 2754
Query: 421 ERLGVQSVRCLSLVSEDMTKDLPCMGYNKVSELLALYGNSEFLLFDLLELADCCKAKKLH 480
RLG+QS+RC+SLV D+T+DLPCM + K+ ELL+LY + +FLLFDLLELADCCK KKLH
Sbjct: 2755 NRLGIQSLRCISLVDNDITQDLPCMDFTKLKELLSLYASKDFLLFDLLELADCCKVKKLH 2814
Query: 481 LIYDKREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSNFQLLPPWKLRGNTLNYGL 540
+I+DKREHPR++LLQHNLGEFQGPA+VAI EG L+REE + QLL W+++G TLNYGL
Sbjct: 2815 IIFDKREHPRKTLLQHNLGEFQGPAIVAILEGVTLTREEICSLQLLSQWRIKGETLNYGL 2874
Query: 541 GLVGCYSICDLLSVVSGGYFYMFDPRGLVLSAPSSNAPSGKMFSLIGTDLAQRFGDQFSP 600
GL+ CY +CDLLS+VSGGYFYMFDP+G LSA ++ AP+GKMFSLIGT+L +RF DQF+P
Sbjct: 2875 GLLSCYFMCDLLSIVSGGYFYMFDPQGATLSASTTQAPAGKMFSLIGTNLVERFSDQFNP 2934
Query: 601 MLIDQNDLWSLSDSTIIRMPLSSDCLKVGHDVASNRIKHITDVFMEHGSRTLLFLKSVLQ 660
MLI Q+ WSL+DSTIIRMPLS++ LK G + +R+K I+D F+E+ SR L+FLKSV Q
Sbjct: 2935 MLIGQDKAWSLTDSTIIRMPLSTEILKDGFEAGLDRVKQISDQFLENASRILIFLKSVSQ 2994
Query: 661 VSISTWEEGHSHPCQNFSISIDPSSSIMRNPFSEKKWRKFQLSRLFSSSNTAIKMHVIDV 720
VS STWE+G++ P Q++++ ID +S+IMRNPF+EK + +LSR+F SSN+ +K +I+V
Sbjct: 2995 VSFSTWEQGNAQPHQDYTLHIDSASAIMRNPFAEKNLKTSKLSRIFGSSNSGVKSRIIEV 3054
Query: 721 SLYSEGTTFIDRWLLALSLGSGQTRNMALDRRYLAYNLTPVAGIAALISRNGHHADVYST 780
+L+ +DRWL+ LS GSGQ++NMA R+YLAYNLTPVAG+AA +SRNG DV++
Sbjct: 3055 NLHIGENKLLDRWLVVLSKGSGQSQNMARGRKYLAYNLTPVAGVAAHVSRNGRPVDVHAA 3114
Query: 781 SSIMTPLPLSGCINLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNRE 840
S IM+PLPLSG +NLPVT+LGCFL+ +N GR+LFK ++ RA +E DAG+ LI+ WN+E
Sbjct: 3115 SPIMSPLPLSGSVNLPVTILGCFLIRNNCGRFLFKNKNERAMSEPQLDAGDILIDAWNKE 3174
Query: 841 LMSCVCDSYVEMILEIQNLRKDVSSSIIDSSACPGINLSLKAYGDNIYSFWPRSSEGHVP 900
LMSCV DSY+E+++E++ L ++ SSS +SS + LSLKAYG +YSFWPRS++
Sbjct: 3175 LMSCVRDSYIEIVVEMERLSREHSSSSTESSTARQLALSLKAYGHQLYSFWPRSNQ---- 3230
Query: 901 SGQLFDHNNTPSSSTAVLKADWECLKERVIHPFYSRIVDLPVWQLYSGNLVKAGEGMFLS 960
+ + VLK +WECL E+VI PFY+R+ DLP+WQLYSG+LVKA EGMFL+
Sbjct: 3231 --------HDDAIEAEVLKPEWECLVEQVIRPFYARVADLPLWQLYSGSLVKAEEGMFLT 3282
Query: 961 QPGNGMIGSLLPGTVCSFVKEHYPVFSVPWELVTEIQVVGFSVREVRPKMVRDLLKVSSK 1020
QPG+ + +LLP TVCSFVKEHYPVFSVPWEL+ E+Q VG VREV+PKMVR LL+ SS
Sbjct: 3283 QPGSEVAVNLLPLTVCSFVKEHYPVFSVPWELLAEVQAVGIPVREVKPKMVRVLLRKSSA 3342
Query: 1021 PIVLRSVDMYIDVLEYCLSNFQQSVPSSLPRDSAQVDPTNINVICRETDVGSTSQPESNI 1080
I LRSVD +IDVLEYCLS+ Q +L + A +D N STS
Sbjct: 3343 SIDLRSVDTFIDVLEYCLSDIQ--FIEALNPEEANMDEGN-----------STS------ 3383
Query: 1081 HSSTGIASQGADSSGDALEMMTSLGKVLIDFGRGVVEDIGRAGAPLAYRNAVTGTGQNRD 1140
+S+ +++Q S DA EMMTSLGK L DFGR VVEDIGR G + R + N D
Sbjct: 3384 -TSSSMSTQAQAGSSDAFEMMTSLGKALFDFGRVVVEDIGRTGDSIGQRIS-NNRYSNAD 3441
Query: 1141 QKFVSIAAELKGLPCPTATNHLQKLGLTELWIGNKEQQSLMDPLREKFVHPKVLERPLLG 1200
+F+S ELKGLPCPTATNHL +LG++ELW+GNKEQQ+LM P+ +F+HPKV ER L
Sbjct: 3442 PRFLSAVNELKGLPCPTATNHLARLGISELWLGNKEQQALMLPVSARFIHPKVFERSSLA 3501
Query: 1201 EIFSNLSLQGLLKLQNFSLHLLANHMKLIFHEDWVNHVMGSNMAPWLSWKKLPSSDSQGG 1260
+IF S+Q LKL+++SL LLA++MK +FH+ WV+++ SN PW SW+ SS G
Sbjct: 3502 DIFLKSSVQAFLKLRSWSLPLLASNMKYLFHDHWVSYISESNSVPWFSWESTSSSSDDSG 3561
Query: 1261 PSSEWIKIFWKSFRGSQEELSLFSDWPLIPAFLGRPVLCRVRERHLVFIPPPLVQRTLQS 1320
PS EWI++FWK+F GS +ELSLFSDWPLIPAFLGRP+LCRVRERHL+F PPP +Q +S
Sbjct: 3562 PSPEWIQLFWKNFNGSADELSLFSDWPLIPAFLGRPILCRVRERHLIFFPPPALQPVSRS 3621
Query: 1321 GILDRESTENHVGGVSVSRDDTS-VAEAYTSAFDRLKISYPWLLSLLNQCNVPIFDEAFI 1379
G D T++ + SVS S + + Y S FD + +PWL+ LLNQCN+P+ D A+I
Sbjct: 3622 GT-DMHQTDSDISTTSVSGGPLSELTQRYVSGFDLAQSKHPWLILLLNQCNIPVCDTAYI 3680
Query: 1380 DCATSSNCFSMPGGSLGQVIASKLVAAKQAGYFTEPNNLSASSCDALFSLFCDELFSNGF 1439
DCA C P SLGQ IASKL K+AGY + + D LF+L ++ S+G
Sbjct: 3681 DCAERCKCLPSPSVSLGQAIASKLAEGKRAGYIADIASFPTFGRDELFTLLANDFSSSGS 3740
Query: 1440 HYAQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPSNSFFKPHDEHCLSYATDSNGSSFL 1499
Y E+E+L SLPI+KTV GSYT L+ C+I +SF KP+DE C Y DS FL
Sbjct: 3741 SYQAYELEVLSSLPIFKTVTGSYTHLQRHGLCIISGDSFLKPYDECCFCYLPDSVECHFL 3800
Query: 1500 RALGVLELNDQQILVRFGLPGYERKSMNEQEDILIYVFKNWHDLQSNQSVVEALKETKFV 1559
+ALGV L++ Q LVRFGL +E +S +E+EDILIYV+ NW DL+ + V+EAL+E KFV
Sbjct: 3801 QALGVTVLHNHQTLVRFGLAEFESRSQSEREDILIYVYGNWLDLEVDSDVIEALREAKFV 3860
Query: 1560 RNSDEFSTDLLKPKELFDPADAILISIFFGERKKFPGERFSTDGWLRILRKLGLRTATEV 1619
RNSDEFS++L K K+LFDP+D +L+S+FFGERK+FPGERFS++GWLRILRK GLRTA E
Sbjct: 3861 RNSDEFSSELSKSKDLFDPSDTLLVSVFFGERKRFPGERFSSEGWLRILRKAGLRTAAEA 3920
Query: 1620 DVIIECAKRVEFLGIECMKSGDLDDFEADTTNSRAEVSPEVWALGGSVVEFIFSNFALFF 1679
DVI+ECAKRVEFLG E +S + DDFE D +S ++S E+ L GSV+E I NFA F+
Sbjct: 3921 DVILECAKRVEFLGNERNRSSEEDDFETDLVHSEKDISVELSTLAGSVIEAILLNFAGFY 3980
Query: 1680 SNNFCDLLGKIA-----------------------------------------------F 1692
S FC+ LG+IA F
Sbjct: 3981 STAFCNTLGQIACVPAESGFPSLGGRKGGKRVLTRYSEAVLLRDWPLAWSSVPILSTQRF 4040
Query: 1693 VPSELGFPSVGCK------------RVIGKNGGEDTLAHWPIASGLKNIEECTCEILKYL 1740
+P + ++ K +VIG+NGGEDTLAHWP + I+ +CE+LKYL
Sbjct: 4041 IPPGFSWTALRLKSPPIFSTVLKHLQVIGRNGGEDTLAHWPNDPNVMTIDVTSCEVLKYL 4100
Query: 1741 DKIWGSLSPS 1750
+ +W SL+ S
Sbjct: 4101 EIVWDSLTTS 4110
Score = 294 bits (753), Expect = 2e-77
Identities = 245/846 (28%), Positives = 390/846 (45%), Gaps = 94/846 (11%)
Query: 1 LYDPRVPELKKMLHGDVFFPSDKFLDPEILDTLVCLGLRTTLGFTGLLDCARSVSLLHDS 60
L+DPR EL +L FP+ F ILD L LGL+TT+ +L+ AR V L
Sbjct: 947 LHDPRNEELYALLEDSDCFPASGFQGSAILDMLQGLGLKTTVSPETILESARLVERLMHK 1006
Query: 61 GDTEASKHGKGLLVFLDKLACKLSSNGESENDDQSLAVRSNITMDDAVVYDGFPKDENSL 120
+A GK L FL+ A K + SE DD + F + +
Sbjct: 1007 DLEKAHSRGKVLFSFLEVNAVKWLPDQSSE--------------DDGAINRIFSRAATAF 1052
Query: 121 IDDVDLFMSSLINDMVEEEFWSELKLITWCPVILDPAVRGLPWLKSSKQVALPTVVRPKS 180
+L ++V+ FWSELK+I WCPV++ + LPW + VA P +VRPK+
Sbjct: 1053 RP------RNLTCNLVK--FWSELKMICWCPVLVSAPFQTLPWPVVTSTVAPPKLVRPKT 1104
Query: 181 QMWLVSSSMLILDGECGTTYLQTKLGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDF 240
MWLVS+SM ILDGEC +T L LGW+ P ++ QL+EL K+ L+D
Sbjct: 1105 DMWLVSASMRILDGECSSTALAYNLGWLSHPGGSAIAAQLLELGKN-----NEILIDQVL 1159
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDFVSPNALAFDSPVKFTPY 300
+L +P +YS L + +D+ + +KA L+G W+W+GD F + + + D P++ PY
Sbjct: 1160 RQELALAMPKIYSILARLLGSDEMDIVKAVLEGSRWIWVGDGFATLSEVVLDGPLQLVPY 1219
Query: 301 LYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCVHEAI 360
+ V+ ++L+ ++ L ++LGVR DY VL R+ PL ++ + + +
Sbjct: 1220 IRVIPTDLAVFRGLFVELGVREFLTPSDYADVLCRIAVRKGTSPLDPQEIRAAVLIAQQL 1279
Query: 361 AEC-CLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWL------------ENSSLIG 407
AE L+K +++PD G L + DLVYNDAPWL E++ L+
Sbjct: 1280 AEAQFLDK-------VTIYLPDVSGRLFPSSDLVYNDAPWLTASDNLNSSFSAESTMLLN 1332
Query: 408 -----RHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMG-----------YNKVS 451
+ FVH +ISN++AE+LGV+S+R + L + + G ++
Sbjct: 1333 AKRTMQKFVHGNISNEVAEKLGVRSLRRVLLAESADSMNFSLSGAAEAFGQHEALTTRLK 1392
Query: 452 ELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFE 511
+L +Y + +LF+L++ A+ A ++ + DK + SLL + ++QGPAL
Sbjct: 1393 HILEMYADGPGILFELVQNAEDAGASEVTFLLDKTHYGTSSLLSPEMADWQGPALYCFNN 1452
Query: 512 GACLSREEFSNFQLLPPWKLRGNTL--NYGLGLVGCYSICDLLSVVSGGYFYMFDPRGLV 569
++ ++ ++ KL +GLG Y D+ VSG MFDP
Sbjct: 1453 SVFTQQDMYAISRIGQASKLEKPFAIGRFGLGFNCVYHFTDIPGFVSGENIVMFDPHANH 1512
Query: 570 LSAPSSNAPSGKMFSLIGTDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPLSSDCLKVG 629
L S P G G + +F DQF+P L DL T+ R PL + +
Sbjct: 1513 LPGISPTHP-GLRIKFAGRYILDQFPDQFAPFLHFGCDLEHTFPGTLFRFPLRNASVAPR 1571
Query: 630 HDV-----ASNRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEEGHSHP-------CQNF 677
+ A + + F S L+FL++V VSI T +EG H C++
Sbjct: 1572 SHIKKETYAPEDVLSLFTSFSGVVSEALIFLRNVKTVSIFT-KEGAGHEMQLLHRVCKDH 1630
Query: 678 SISID----PSSSIMRNPFSEKKWRKFQLSRLFSS-SNTAI-----KMHVIDVSLYSEGT 727
++ D PSS + + E + +L SNT + K I V+
Sbjct: 1631 NVGQDTEPKPSSQVF-SLLDENIFAGMNKDQLLKKLSNTVVKDLPYKCQKIVVTEQDSSG 1689
Query: 728 TFIDRWLLALSLGSGQTRNMALDRRYLAYNLTPVAGIAALIS--RNGHHADV-YSTSSIM 784
+ W+ L +G ++ L+ +++ L P A +A I+ +N + D+ S S+I
Sbjct: 1690 CILHGWITGECLNAGVSKK-NLNLPEMSHKLIPWASVAVHINSVKNENVEDLAASISNIF 1748
Query: 785 TPLPLS 790
P +S
Sbjct: 1749 GPSTIS 1754
Score = 131 bits (329), Expect = 2e-28
Identities = 159/647 (24%), Positives = 260/647 (39%), Gaps = 126/647 (19%)
Query: 432 SLVSEDMTKDLPCMGYNKVSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQ 491
SL+ ED + + ++ E+L Y +L +L++ AD A K+ L D+R H
Sbjct: 3 SLLLEDFGQKVDLT--RRIREVLLNYPEGTTVLKELIQNADDAGATKVRLCLDRRVHGSG 60
Query: 492 SLLQHNLGEFQGPALVAIFEGACLSREEFSNFQLLPPWKLRG---NTLNYGLGLVGCYSI 548
SLL +L ++QGP+L+A + A + E+F + + G T +G+G Y +
Sbjct: 61 SLLSDSLAQWQGPSLLA-YNDAVFTEEDFVSISRIGGSGKHGQAWKTGRFGVGFNSVYHL 119
Query: 549 CDLLSVVSGGYFYMFDPRGLVLSAPSSNAPSGKMFSLIGTDLAQRFGDQFSPMLIDQNDL 608
D+ S VSG Y +FDP+G L S+ P GK +G+ ++ DQF P D+
Sbjct: 120 TDIPSFVSGKYVVLFDPQGAYLPNISAANP-GKRIDYVGSSALSQYKDQFLPYCAFGCDM 178
Query: 609 WSLSDSTIIRMPLSSDCLKVGHDVASNRIKH----------ITDVFMEHGSRTLLFLKSV 658
S + T+ R PL + AS+R+ + D E G +LLFLK V
Sbjct: 179 RSPFNGTLFRFPLRNT-----EQAASSRLSRQAYFEDDISLMFDQLFEEGVFSLLFLKCV 233
Query: 659 LQVSISTWEEGHSHPCQNFSISIDPSSSIMRNPFSEKKWRKFQLSRLFSSSNTAIK-MHV 717
L + + TW++G S P + +S S+ +P ++ W + + RL +S + + M
Sbjct: 234 LSIEMYTWDDGDSEPKKLYSCSVS-------SPNNDTVWHRQAVLRLSKTSISGDREMDA 286
Query: 718 IDVSLYSEG------TTFIDRWLLALSLGSGQTR---NMALDRRYLAYNLTPVAGIAALI 768
+ SE DR+ + ++ S ++ A + +L P A +AA I
Sbjct: 287 FTLEFLSESEKGNQTKRRTDRFYIVQTMASASSKIGLFAATASKEYDIHLLPWASVAACI 346
Query: 769 SRNGHHADVYSTSSIMTPLPLSGCINLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFD 828
S + ++ LPL L V V G F V NR R ++ +D D
Sbjct: 347 SDDSSENNILKLGHAFCFLPLPVRTGLTVQVNGYFEVSSNR-RGIWYGED--------MD 397
Query: 829 AGNQLIELWNRELM-SCVCDSYVEMILEIQNLRKDVSSSIIDSSACPGINLSLKAYGDNI 887
++ WNR L+ V S+ ++L ++ ++DS D+
Sbjct: 398 RSGKVRSAWNRLLLEDVVAPSFARLLLCLR--------EVLDSR-------------DSY 436
Query: 888 YSFWPRSSEGHVPSGQLFDHNNTPSSSTAVLKADWECLKERVIHPFYSRIVDLPVW--QL 945
+S WP S +A W L E++ Y I + PV L
Sbjct: 437 FSLWPSGS----------------------FEAPWSILVEQI----YKNICNAPVLFSDL 470
Query: 946 YSGNLVKAGEGMFLSQPGNG------------MIGSLLPGTVCSFVKEHYPVFSVPWELV 993
G V + + +G M LP V + +H P F +P
Sbjct: 471 DGGKWVSPADAYLHDEEFSGSKDLGDALLQLEMPIVCLPRLVFDMLLKH-PSFLLP---- 525
Query: 994 TEIQVVGFSVREVRPKMVRDLLKVSSKPIVLRSVDMYIDVLEYCLSN 1040
+ V P VR+ LK K + + + +LEYCL +
Sbjct: 526 ----------KVVTPDRVRNFLK-ECKTLSALKKSLKLVLLEYCLDD 561
Score = 56.6 bits (135), Expect = 7e-06
Identities = 90/413 (21%), Positives = 157/413 (37%), Gaps = 63/413 (15%)
Query: 1244 APW-LSWKKLPSSDSQGGPSSEWIKIFWKSFRGSQEELSLFSDWPLIPAFLGRPVLCRVR 1302
A W LS K L + +G P+ EWI++ W + S ++LS+FS WP++P G C
Sbjct: 2060 ADWHLSEKILWTPGQRGHPTVEWIRVLWSYLKLSCDDLSVFSKWPILPVEDG----C--- 2112
Query: 1303 ERHLVFIPPPLVQRTLQSGILDRESTENHVGGVSVSRDDTSVAEAYTSAFDRLKISYPWL 1362
L+Q L S ++ + ++ + + + L + +P L
Sbjct: 2113 ----------LMQLILNSNVIRDDGWSENMSSLLLKCGCRFLNR-------ELPVEHPQL 2155
Query: 1363 LSLLNQCNVPIFDEAFIDCATSSNCFSMPGGSLGQVIASKLVAAKQAGYFTEPNNLSASS 1422
E F+ T++ G L ++A G F N+S
Sbjct: 2156 -------------ETFVQPPTAT-------GILNALLAISGGHENIKGIFL---NVSEGE 2192
Query: 1423 CDALFSLFCDELFSNGFHYAQEEIEILRSLPIYKTVVG-SYTKLKDQDQCMIPSNSFFKP 1481
L + + +G H + E ++ LPI+++ L + + P
Sbjct: 2193 LHELRNFILQSKWFSGGHMNEVHFETIKHLPIFESYRSRKLVSLNCPVKWLKPDGIREDL 2252
Query: 1482 HDEHCLSYATDSNGSSFLRALGVLELNDQQILVRFGLPGYERKSMNEQEDILIYVFKNWH 1541
D+ + ++ + F R L + E + + L Q++ L+ + + +
Sbjct: 2253 LDDDFVRLDSERERTIFKRYLQIKEPSKMEFYKACVL--NRMSEFLSQQEALLAILHDLN 2310
Query: 1542 DL-QSNQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKKFPGERFS 1600
DL ++ S+ A+ T FV ++ +P L+DP L + E FP E+FS
Sbjct: 2311 DLVVADVSLQCAISTTPFVLAANGL---WQQPSRLYDPRVPALQELLHKE-VYFPSEKFS 2366
Query: 1601 TDGWLRILRKLGLRTATEVDVIIECAKRVEFLGIECMKSGDLDDFEADTTNSR 1653
L L LGLRT + ++ A+ V L DL D EA R
Sbjct: 2367 DSKILDALVGLGLRTTLDCSTYLDAARSVSML-------HDLGDLEASRYGRR 2412
Score = 49.3 bits (116), Expect = 0.001
Identities = 89/455 (19%), Positives = 172/455 (37%), Gaps = 72/455 (15%)
Query: 1189 VHPKVLERPLLGEIFSNLSLQGLLKLQN---FSLHLLANHMKLIFHEDWVNHVMGSNMAP 1245
V+ +V+++ + +++ L + N FS+H L + +W +
Sbjct: 610 VYDRVIDKNIPPPLYTRLFAIAESRTANVAIFSIHNLLQLFPRLVPAEWKHRSK------ 663
Query: 1246 WLSWKKLPSSDSQGGPSSEWIKIFWKSFRGSQEELSLFSDWPLIPAFLGRPVLCRVRERH 1305
+SW + D PSS W +FW+ + LSLF DWP++P+ G + + +
Sbjct: 664 -ISWHPESNRDH---PSSSWFVLFWQYLDKRCQSLSLFCDWPILPSTSGYLYIASPQSKL 719
Query: 1306 LVFIPPPLVQRTLQSGILDRESTENHVGGVSVSRDDTSVAEAYTSAFDRLKISYPWLLSL 1365
+ P R +L++ +GG ++ + +K+ + L S
Sbjct: 720 INAEKLPAAVR----NVLEK------IGGKILN--------------NNIKVEHSDLSSF 755
Query: 1366 LNQCNVPIFDEAFIDCATSSNCFSMPGGSLGQVIASKLVAAKQAGYFTEPNNLSASSCDA 1425
++ + E+ D A+S L + Y +L+A D
Sbjct: 756 VSDASYTGVLESIFDAASSD-----------------LDGVQNLIY-----DLNAQEKDE 793
Query: 1426 LFSLFCDELFSNGFHYAQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPSNSFFKPHD-E 1484
L S D + G + I + LPI++ + G + + + ++ P D
Sbjct: 794 LRSFLLDPKWHIGHQIGDLYLRICKILPIHR-IYGETSAQESKYSDLVNPPKHLPPLDVP 852
Query: 1485 HCL---SYATDSNGSS---FLRALGVLELNDQQILVRFGLPGYERKSMNEQEDILIYVFK 1538
CL + GS R G+ + + E ++ ++I + +
Sbjct: 853 ACLLGCEFILCCQGSEEDVLSRYYGIERMRKSNFYRQNVFNRIEVLQPEIRDQVMISILQ 912
Query: 1539 NWHDL-QSNQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKKFPGE 1597
+ L ++ + E L+ +FV + L +P L DP + L ++ + FP
Sbjct: 913 DLPQLCLEDRLLREELQNLEFV---PTVNGPLKRPSVLHDPRNEELYAL-LEDSDCFPAS 968
Query: 1598 RFSTDGWLRILRKLGLRTATEVDVIIECAKRVEFL 1632
F L +L+ LGL+T + I+E A+ VE L
Sbjct: 969 GFQGSAILDMLQGLGLKTTVSPETILESARLVERL 1003
>ref|XP_474331.1| OSJNBa0018M05.18 [Oryza sativa (japonica cultivar-group)]
gi|38344927|emb|CAE03243.2| OSJNBa0018M05.18 [Oryza
sativa (japonica cultivar-group)]
Length = 4666
Score = 1581 bits (4093), Expect = 0.0
Identities = 864/1742 (49%), Positives = 1123/1742 (63%), Gaps = 109/1742 (6%)
Query: 1 LYDPRVPELKKMLHGDVFFPSDKFLDPEILDTLVCLGLRTTLGFTGLLDCARSVSLLHDS 60
LYDPRVPEL K+LH + FFPS+KF+ E+++ L GL++ LGF+ LLD ARSVSL D
Sbjct: 2334 LYDPRVPELHKLLHKETFFPSEKFMTTEVIELLASFGLKSKLGFSTLLDIARSVSLQQD- 2392
Query: 61 GDTEASKHGKGLLVFLDKLACKLSSNGESEN---DDQSLAVRSNITMDDAVVYDGFPKDE 117
+A +HGK LL +L+ L K S+ + + DD A +++ + + DG+ +E
Sbjct: 2393 ---DALEHGKRLLTYLNFLEFKASNMEDKKTFHGDDNQEASKTDGSFEAENDGDGYDPEE 2449
Query: 118 NSLIDDVDLFMSSLINDMVEEEFWSELKLITWCPVILDPAVRGLPWLKSSKQVALPTVVR 177
L LF S+ +D+ E+EFWSELK I+WCPV + P ++GLPW S VA P R
Sbjct: 2450 TIL----SLF-SNFDHDLPEDEFWSELKNISWCPVHVAPLLKGLPWFISEDHVAPPITTR 2504
Query: 178 PKSQMWLVSSSMLILDGECGTTYLQTKLGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLD 237
PKSQMWLVSS M IL + + YLQ KLGW+D PN +LS QL+E+SKSY +LK S D
Sbjct: 2505 PKSQMWLVSSKMRILSADSCSMYLQRKLGWLDPPNANILSSQLVEISKSYDELKMFSE-D 2563
Query: 238 PDFDVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDFVSPNALAFDSPVKF 297
D QKEI +YSKLQ+ I+T D N LK LDG WV+IGD FV P ALAFDSPVK+
Sbjct: 2564 STNDAVPQKEIQLIYSKLQDIIDTADTNILKRNLDGHPWVYIGDRFVPPQALAFDSPVKY 2623
Query: 298 TPYLYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCVH 357
PYLY V SELSEYK L+ LGV+ +F DYL+VLQ LQ+D G PLST+QL+FV V
Sbjct: 2624 HPYLYAVPSELSEYKRLLSVLGVKQTFDAADYLNVLQCLQSDAKGEPLSTEQLSFVHRVL 2683
Query: 358 EAIAECCLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSLIGRHFVHPSISN 417
EA +C + + + L IPD+FGVL A +LVYNDAPW+ N+ + FVH SI N
Sbjct: 2684 EAFVDCYPDNQAPDMMVNSLLIPDSFGVLTPARNLVYNDAPWM-NADPTSKSFVHLSIGN 2742
Query: 418 DLAERLGVQSVRCLSLVSEDMTKDLPCMGYNKVSELLALYGNSEFLLFDLLELADCCKAK 477
DLA RLGV+S+R SL+ +++ DLPCM Y K+SELLALYG S+FLLFDL+ELAD C AK
Sbjct: 2743 DLANRLGVRSLRGSSLLDDELMTDLPCMEYAKISELLALYGESDFLLFDLIELADHCNAK 2802
Query: 478 KLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSNFQLLPPWKLRGNTLN 537
K+HLIYDKR+HP+QSLLQ +LG+FQG +L +FEG +SREE + QL PPWKL+GN LN
Sbjct: 2803 KVHLIYDKRDHPKQSLLQQSLGDFQGSSLTVVFEGTIMSREEVCSLQLPPPWKLKGNILN 2862
Query: 538 YGLGLVGCYSICDLLSVVSGGYFYMFDPRGLVLSAPSSNAPSGKMFSLIGTDLAQRFGDQ 597
YGLGL+ Y +CD LS++SGGYFY+FDP GL S S + FSLIG DL +RF DQ
Sbjct: 2863 YGLGLLSSYFVCDTLSILSGGYFYIFDPLGLTGGTTSIATSSARFFSLIGNDLVERFHDQ 2922
Query: 598 FSPMLIDQNDLWSLSDSTIIRMPLSSDCLKVGHDVASNRIKHITDVFMEHGSRTLLFLKS 657
F+PM + Q S ++ST+IRMPLSS CLK + NR+KHI D F ++ S TLLFL+S
Sbjct: 2923 FTPMRVTQEASLSSANSTVIRMPLSSKCLK-ELEAGCNRVKHIFDRFTQNPSSTLLFLRS 2981
Query: 658 VLQVSISTWEEGHSHPCQNFSISIDPSSSIMRNPFSEKKWRKFQLSRLFSSSNTAIKMHV 717
++QVS+STWE G S P N+S+ +DPS + +RNPFSEKKWRKFQLSR+F+S++ AIKM
Sbjct: 2982 IIQVSLSTWEGGASQPTLNYSVLVDPSVATLRNPFSEKKWRKFQLSRIFASTSAAIKMQA 3041
Query: 718 IDVSLYSEGTTFIDRWLLALSLGSGQTRNMALDRRYLAYNLTPVAGIAALISRNGHHADV 777
IDV + G +ID+W +AL LGSGQTRNMALDRRYLAYNLTPVAG+AA I+RNG ++
Sbjct: 3042 IDVHVIDNGCNYIDKWFVALCLGSGQTRNMALDRRYLAYNLTPVAGVAAHIARNGVSTNI 3101
Query: 778 YSTSSIMTPLPLSGCINLPVTVLGCFLVCHNRGRYLF--KYQDRRASAEGHFDAGNQLIE 835
+++S I++PLPLSG I++PVT LG F+V HN GRY+F + + E H N+L+E
Sbjct: 3102 HASSCILSPLPLSGSISMPVTTLGHFIVRHNGGRYIFGSSHDKSLSDLEMH---KNKLVE 3158
Query: 836 LWNRELMSCVCDSYVEMILEIQNLRKDVSSSIIDSSACPGINLSLKAYGDNIYSFWPRSS 895
WN+ELM CV DSYVEM+LE Q LRKD SS I+S + ++ L+AYGD +YSFWPRS
Sbjct: 3159 AWNKELMLCVRDSYVEMVLEFQKLRKDPLSSAIESRSAHSVSTILQAYGDRVYSFWPRSK 3218
Query: 896 EGHVPSGQLFDHNNTPSSSTAVLKADWECLKERVIHPFYSRIVDLPVWQLYSGNLVKAGE 955
+ H S + T +S KADW+ L E+VI PFY R+ DLPVWQLY GNLVK
Sbjct: 3219 Q-HPASLTGYGSTVTNVNSPRASKADWQSLVEQVIRPFYVRLADLPVWQLYGGNLVKVDV 3277
Query: 956 GMFLSQPGNGMIGSLLPGTVCSFVKEHYPVFSVPWELVTEIQVVGFSVREVRPKMVRDLL 1015
GMFLS G+G +L +VCSF+KEHYPVFSVPWELV EIQ VG +VRE+RPKMVRDLL
Sbjct: 3278 GMFLSHSGSGDDDNLPSASVCSFIKEHYPVFSVPWELVREIQAVGVNVREIRPKMVRDLL 3337
Query: 1016 KVSSKPIVLRSVDMYIDVLEYCLSNFQQSVPSSLPRDSAQVDPTNINVICRETDVGSTSQ 1075
K SS I+LRS++ Y+DVLEYC S+ S + I + S
Sbjct: 3338 KASSS-ILLRSIETYMDVLEYCFSDMDPYRFSDFHIHEESRVSNQQSEIMNSSISNSMPS 3396
Query: 1076 PESNIHSSTGIASQGADSSGDALEMMTSLGKVLIDFGRGVVEDIGRAGAPLAYRNAVTGT 1135
S++ QGA S GDALE++T GK L DFGRGVVEDI + G ++R T
Sbjct: 3397 SSSSVSYHRNTQRQGA-SGGDALEIVTYFGKALYDFGRGVVEDISKTGGSASHR-----T 3450
Query: 1136 GQNRDQKFVSIAAELKGLPCPTATNHLQKLGLTELWIGNKEQQSLMDPLREKFVHPKVLE 1195
+ SI ELKG+P PT+T L +LG TELWI ++EQQ LM P F+H + L+
Sbjct: 3451 QAAENNVLSSIITELKGVPFPTSTKCLTRLGSTELWIASEEQQLLMRPFLHHFIHHQCLQ 3510
Query: 1196 RPLLGEIFSNLSLQGLLKLQNFSLHLLANHMKLIFHEDWVNHVMGSNMAPWLSWKKLPSS 1255
+P L + + + LKL++FS HLL+ H+K IF E WV H+ +PW+ W +S
Sbjct: 3511 KPFLELLLTTQVIHRPLKLRSFSPHLLSGHLKHIFDERWV-HLAVEKKSPWIPWDNNANS 3569
Query: 1256 DSQGGPSSEWIKIFWKSFRGSQEELSLFSDWPLIPAFLGRPVLCRVRERHLVFIPPPLVQ 1315
S GPS EWI++FWK F +LSL SDWPLIPA+L RPVLCRV+E HL+F+PP
Sbjct: 3570 -STAGPSPEWIRLFWKIFSSMSGDLSLLSDWPLIPAYLDRPVLCRVKECHLIFVPP---- 3624
Query: 1316 RTLQSGILDRESTENHVGGVSVSRDDTSVAEAYT---SAFDRLKISYPWLLSLLNQCNVP 1372
S +S V + D+T AE + +AF + ++PWL +LL + N+P
Sbjct: 3625 -ADDSNPDSGDSAARVVDTSAHPGDETGEAELNSILDTAFQSMNSAFPWLPALLYKLNIP 3683
Query: 1373 IFDEAFIDCATSSNCFSMPGGSLGQVIASKLVAAKQAGYFTEPNNLSASSCDALFSLFCD 1432
+FD +F +C T N F +LGQ+IASKLVA K G+ P +LS+ CD LF+LF
Sbjct: 3684 VFDLSFPECGTICNLFPSRDRTLGQIIASKLVAIKNGGHLPLPLSLSSEDCDKLFALFVS 3743
Query: 1433 EL-FSNGFHYAQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPSNSFFKPHDEHCLSYAT 1491
E S+ Y +EE+++LR LP+YKTV G+YT L D C++ +FF P D CLS +
Sbjct: 3744 EFRLSSNHLYQREELDVLRELPMYKTVTGTYTSLSGSDHCILSPTAFFHPADSRCLS--S 3801
Query: 1492 DSNGSSFLRALGVLELNDQQILVRFGLPGYERKSMNEQEDILIYVFKNWHDLQSNQSVVE 1551
+N FL+ALGV +L+DQ+ILVR
Sbjct: 3802 TANADLFLQALGVEQLSDQEILVR------------------------------------ 3825
Query: 1552 ALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKKFPGERFSTDGWLRILRKL 1611
+++ +EL DP+DA+L S+F GER KFP ERF +DGWL ILRK
Sbjct: 3826 -----------------VVQTRELLDPSDALLTSVFSGERHKFPAERFLSDGWLVILRKA 3868
Query: 1612 GLRTATEVDVIIECAKRVEFLGIECMKSG-DLDDFEADTTNSRAEVSPEVWALGGSVVEF 1670
GLRT+TE D+I++CA ++E +G + + S D DFEAD + S+ E+ E+W+L SVV
Sbjct: 3869 GLRTSTEADMIVQCATKIESMGNDIVSSSEDPSDFEADFSGSKNEIPFELWSLAESVVNV 3928
Query: 1671 IFSNFALFFSNNFCDLLGKIAFVPSELGFPSVGCKRVIGKNGGEDTLA---------HWP 1721
I +NFA + ++FC+ +GKIAF+P+E GFPS+G GK GG LA WP
Sbjct: 3929 ILANFATLYDSSFCENIGKIAFIPAEKGFPSIG-----GKRGGRRVLASYSESILSKDWP 3983
Query: 1722 IA 1723
+A
Sbjct: 3984 LA 3985
Score = 305 bits (780), Expect = 1e-80
Identities = 282/1119 (25%), Positives = 475/1119 (42%), Gaps = 154/1119 (13%)
Query: 1 LYDPRVPELKKMLHGDVFFPSDKFLDPEILDTLVCLGLRTTLGFTGLLDCARSVSLLHDS 60
LYDPRV EL +L FP F +PE+LD L+CLGLRT++ ++ AR + L
Sbjct: 932 LYDPRVEELYALLQESDCFPHGLFQNPEVLDMLLCLGLRTSVSIDTIIQSARHIDSLVHK 991
Query: 61 GDTEASKHGKGLLVFLDKLACKLSSNGESENDDQSLAVRSNITMDDAVVYDGFPKDENSL 120
+A GK LL +L+ A K + + R + M V +D +
Sbjct: 992 DHHKAHSRGKVLLSYLEVHAHKWYVHKPFDG-------RKKVNMLAKVTTVLRSRDTSW- 1043
Query: 121 IDDVDLFMSSLINDMVEEEFWSELKLITWCPVILDPAVRGLPWLKSSKQVALPTVVRPKS 180
+ DL E+FWS+L++I WCPV++ LPW S VA P VR +
Sbjct: 1044 --EADL-----------EKFWSDLRMICWCPVLVTAPSPALPWPSVSSMVAPPKQVRMQD 1090
Query: 181 QMWLVSSSMLILDGECGTTYLQTKLGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDF 240
MW+VS+S ILDGEC ++ L LGW+ P+ V++ QL+EL K+ ++ T +L +
Sbjct: 1091 DMWIVSASSRILDGECTSSALSYSLGWLSPPSGSVIAAQLLELGKN-NEIVTDQVLRQE- 1148
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDFVSPNALAFDSPVKFTPY 300
L +P +YS L I +D+ + +K L+G W+W+GD F + + + PY
Sbjct: 1149 ---LALVMPKIYSLLSNLIGSDEMDIVKVVLEGCRWIWVGDGFAKTDEVVLTGHLHLAPY 1205
Query: 301 LYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCVHEAI 360
+ V+ +L+ +KDL ++LG++ +DY +L R+ L ++L V + +
Sbjct: 1206 IRVIPIDLAVFKDLFLELGIKEQLDPVDYASILTRMATRKASTSLQAEELRTAVLVVQHL 1265
Query: 361 AECCLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWL---------------ENSSL 405
AE F+ + +++PD+ L + +LV+NDAPWL NS
Sbjct: 1266 AEF-----RFQDHQTQIYLPDSSARLCLSSELVFNDAPWLLDFDEDITGNAPSIAFNSKK 1320
Query: 406 IGRHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGY-----------NKVSELL 454
+FVH +ISND+AERLGV+S+R L L + +L G ++ ++
Sbjct: 1321 YVHNFVHGNISNDVAERLGVRSLRRLLLAESSDSMNLSLSGVAEAFGQHEDLTTRLKHIV 1380
Query: 455 ALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFEGAC 514
+Y + +LF+L++ A+ KA ++ + DK + S+L + E+QGPAL +
Sbjct: 1381 EMYADGPGILFELVQNAEDAKASEVVFLLDKTHYGTSSILSPEMAEWQGPALYCFNDSIF 1440
Query: 515 LSREEFSNFQLLPPWKLRGNTL--NYGLGLVGCYSICDLLSVVSGGYFYMFDPRGLVLSA 572
++ ++ ++ KL +GLG Y D+ VSG MFDP L
Sbjct: 1441 SPQDLYAISRIGQDSKLEKPFAIGRFGLGFNCVYHFTDIPGFVSGENIVMFDPHASYLPG 1500
Query: 573 PSSNAPSGKMFSLIGTDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPLSSDCLKVGHDV 632
S + P G +G + ++F DQF+P L +L T+ R PL ++ +
Sbjct: 1501 ISPSHP-GLRIKFVGRRILEQFPDQFTPFLHFGCNLQQPFPGTLFRFPLRNEAAASRSQI 1559
Query: 633 ASNR-----IKHITDVFMEHGSRTLLFLKSVLQVSISTWEEGHSHPCQNFSISIDPSSSI 687
+ ++ + F E S LLFL++V +++ E +S S +
Sbjct: 1560 KREQYTPQDVEMLFSSFSEVVSEALLFLRNVKNITLYVKESDSQEMKLVHRVSKHNSYEM 1619
Query: 688 MRNPFSEKKWRKF-------------QLSRLFSSSNTAIKMHVIDVSLY--SEGTTFIDR 732
+ P + F ++L + ++ + VS++ S +
Sbjct: 1620 AKEPHALNTMLAFINGNQPSGMDRNQFFNKLNKTKDSDLPWSSQKVSIFEQSPAACLVHS 1679
Query: 733 WLLALSLGSGQTRNMALDRRYLAYNLTPVAGIAALISRNGHHADVYSTSSIMTPLPLSGC 792
W+L S+G R ++ ++ P A +AA + H V +T +
Sbjct: 1680 WILTESIGGXHARKLSTASGSKSHFFVPWASVAAYL----HSVTVDNTKELSGEAE---- 1731
Query: 793 INLPVTVLGCFLVCHNRGRYLFKYQ-----------DRRASAEGHFDAGNQLIELWNREL 841
+NL VL + ++ R F+ + +F+ + ++W
Sbjct: 1732 VNLDDLVLKQLSLGSSKDRKFFEGRAFCFLPLPINTSMPVHVNAYFELSSNRRDIWIGND 1791
Query: 842 MSCVCDSYVEMILEIQNLRKDVSSSIIDSSACPGINLSLKAY------GDNIYSFWPRSS 895
M+ +R + + ++++ A P L A D SFWP
Sbjct: 1792 MA-----------GGGRVRSEWNLALLEDVAAPAYGHLLAAIAQELGPSDLFLSFWP--- 1837
Query: 896 EGHVPSGQLFDHNNTPSSSTAVLKADWECLKERVIHPFYSRIVDLPVWQLYS----GNLV 951
TAV W + + Y I +L + LY+ G+ V
Sbjct: 1838 -------------------TAVGVEPWSSM----VRKLYVSIAELGLHVLYTKARGGHWV 1874
Query: 952 KAGEGMFLSQPGNGMIGSLLPGTVCSFVKEHYPVFSVPWELVTEIQVVGFSVREVRPKMV 1011
+ +F P ++ V S + PV SV ++V SV + P ++
Sbjct: 1875 STRQAIF---PDFSFSKAIELAEVLS--EAGLPVVSVSKQIVDSFLNAYPSVHLLNPHLL 1929
Query: 1012 RDLLKVSSKPIVLRSVDMYIDVLEYCLSNF-QQSVPSSL 1049
R+LL + R+ + I VLEYCLS+ S P L
Sbjct: 1930 RNLLIRRKRG--FRNREEAILVLEYCLSDMGDPSFPDKL 1966
Score = 102 bits (255), Expect = 9e-20
Identities = 110/434 (25%), Positives = 182/434 (41%), Gaps = 62/434 (14%)
Query: 449 KVSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVA 508
++ E+LA Y L +L++ AD A ++ L D+R H SLL L ++QGPAL+A
Sbjct: 20 RIREVLANYPEGTTALRELIQNADDAGASRVRLCLDRRAHGAGSLLAPALAQWQGPALLA 79
Query: 509 IFEGACLSREEFSNF-------QLLPPWKLRGNTLNYGLGLVGCYSICDLLSVVSGGYFY 561
+ A + E+F++ ++ WK T +G+G Y + DL S VSG Y
Sbjct: 80 -YNDAVFTDEDFASISRIGDSRKVSQVWK----TGRFGVGFNSVYHLTDLPSFVSGKYIV 134
Query: 562 MFDPRGLVLSAPSSNAPSGKMFSLIGTDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPL 621
+FDP+G L S+ P GK + + + DQ SP D+ + T+ R PL
Sbjct: 135 LFDPQGAYLPNVSAANP-GKRIDFVSSSAITLYNDQLSPYCAFGCDMKAPFQGTLFRFPL 193
Query: 622 ----SSDCLKVGHDV-ASNRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEEGHSHPCQN 676
+ ++ V + I + E LLFLK+VL + + WE G S P
Sbjct: 194 RTAEQASLSRLSRQVYTEDDILSLFAQLYEEAVYNLLFLKNVLSLEMYVWESGMSEPKIV 253
Query: 677 FSISIDPSSSIMRNPFSEKKWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLA 736
+S SI +R W + L R ++ + + + S+ +F+
Sbjct: 254 YSCSIGSQHDNLR-------WHRQALVRFSGTAAESSEKKIDSFSMDFVSKSFLGE---- 302
Query: 737 LSLGSGQTRNMALDRRYLAYNLTPVAGIAALISRNGHHADVYSTSSIMTPLP---LSGCI 793
+++ Y + V G+A+ +S+ G A + + LP ++ CI
Sbjct: 303 -----------KFEKKSYTYFI--VQGMASALSKIGIFATTAAKDYDLHLLPWASVAACI 349
Query: 794 N-------LPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNRELM-SCV 845
+ L V V G F V NR R D G +L WN L+ V
Sbjct: 350 SNVGPETGLSVHVNGYFEVSSNR---------RDIWYGADMDRGGKLRSDWNMLLLEDVV 400
Query: 846 CDSYVEMILEIQNL 859
+ E++L+++ +
Sbjct: 401 APLFRELLLQLRTV 414
Score = 69.3 bits (168), Expect = 1e-09
Identities = 86/405 (21%), Positives = 155/405 (38%), Gaps = 69/405 (17%)
Query: 1245 PWL---SWK---KLPSSDSQGG--PSSEWIKIFWKSFRGSQEELSLFSDWPLIPAFLGRP 1296
PWL WK ++P GG P++ W K+FW+ +L LFSDWP++P+
Sbjct: 636 PWLFPPGWKCRNQVPWDPESGGSSPTAAWFKLFWQYIGDCSYDLDLFSDWPILPS----- 690
Query: 1297 VLCRVRERHLVFIPPPLVQRTLQSGILDRESTENHVGGVSVSRDDTSVAEAYTSAFDRLK 1356
SG L R ST + + T + L
Sbjct: 691 ----------------------TSGHLYRASTVSKL--------------INTGSLSNL- 713
Query: 1357 ISYPWLLSLLNQCNVPIFDEAFIDCATSSNCFSMPGGSLGQVIASKLVAAKQAGYFTEP- 1415
+ LL + I D ++ + + G + G V+ S A G +
Sbjct: 714 -----MKELLTKLGCKILDTKYLSTCQHLSNYVYDGDASG-VLHSIFGVASLEGVDLQAL 767
Query: 1416 -NNLSASSCDALFSLFCDELFSNGFHYAQEEIEILRSLPIYKTVVGS------YTKLKDQ 1468
++ + + L+ D + G H + I + + LPI++ G ++ L
Sbjct: 768 FQRITPAEKNELYQFVLDAKWYLGPHLSDMSINLCKKLPIFRVFDGGSPSSYGFSDLSTS 827
Query: 1469 DQCMIPSNSFFKPHDEHCLSYATDSNGSSFLRALGVLELNDQQILVRFGLPGYERKSMNE 1528
+ + P + ++ + + S+ +R G+ + R+ L +
Sbjct: 828 RKYLPPLGVAEQLLNDDFVFCISPSDEDIIMRYYGIERMPKSNFYQRYVLNRLDELQTEF 887
Query: 1529 QEDILIYVFKNWHDLQ-SNQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISIF 1587
++ +L+ + ++ L N EALK +FV ++ L P+ L+DP L ++
Sbjct: 888 RDSVLLTILQDLPQLSLENPRFKEALKVLRFVPTTNGV---LKSPQSLYDPRVEELYALL 944
Query: 1588 FGERKKFPGERFSTDGWLRILRKLGLRTATEVDVIIECAKRVEFL 1632
E FP F L +L LGLRT+ +D II+ A+ ++ L
Sbjct: 945 -QESDCFPHGLFQNPEVLDMLLCLGLRTSVSIDTIIQSARHIDSL 988
Score = 61.2 bits (147), Expect = 3e-07
Identities = 24/43 (55%), Positives = 33/43 (75%)
Query: 1708 IGKNGGEDTLAHWPIASGLKNIEECTCEILKYLDKIWGSLSPS 1750
+G+ GEDTLAHWP +SG+ +E+ IL+YLDKIWG++S S
Sbjct: 4025 VGRGNGEDTLAHWPTSSGIMTVEDAFLRILQYLDKIWGTISSS 4067
Score = 48.5 bits (114), Expect = 0.002
Identities = 84/404 (20%), Positives = 149/404 (36%), Gaps = 85/404 (21%)
Query: 1254 SSDSQGGPSSEWIKIFWKSFRGSQEELSLFSDWPLIPAFLGRPVLCRVRERHLVFIPPPL 1313
S QG PS EW+ W R S E+LS+F+ WP++P G+
Sbjct: 2063 SPGHQGQPSVEWMVSLWNFLRHSCEDLSIFAKWPILPLVDGK------------------ 2104
Query: 1314 VQRTLQSGILDRESTENHVGGVSVSRDDTSVAEAYTSAFDR--LKISYPWLLSLLNQCNV 1371
++ + N + S + S+ + F R L+I +P L +
Sbjct: 2105 --------LMQLGNASNVIIDDGWSENMYSLLQKLGCFFLRSDLQIEHPQLAN------- 2149
Query: 1372 PIFDEAFIDCATSSNCFSMPGGSLGQVIASKLVAAKQAGYFTEPNNLSASSCDALFSLFC 1431
F+ AT+ + Q +AS K+ +S + L S
Sbjct: 2150 ------FVQEATAVGVLNAV-----QSVASNFQDIKELFM-----GISLAETHELRSFIF 2193
Query: 1432 DELFSNGFHYAQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPS-NSFFKPHDEHCLSYA 1490
+ +G H + +R+LPI+++ K ++ + S + KP H
Sbjct: 2194 QSKWFSGNHMNSSHMNTIRNLPIFES-------YKSRELVSLTSPRKWLKPEGVH----- 2241
Query: 1491 TDSNGSSFLRALGVLELNDQQILVRFGLPGYERKSMNEQEDILIYVFKNWHD-------- 1542
D SF+R E + ILV + +K+ ++ +L + +
Sbjct: 2242 EDLLNESFIRTESAKE---KSILVSYFAIREPQKAEFYKDHVLPRISEFLSQPAVVSAIL 2298
Query: 1543 ------LQSNQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKKFPG 1596
+++ SV AL ET FV + S + P L+DP L + E FP
Sbjct: 2299 RDVKLLAENDTSVRAALHETPFVLAA---SGAWVHPSRLYDPRVPELHKLLHKE-TFFPS 2354
Query: 1597 ERFSTDGWLRILRKLGLRTATEVDVIIECAKRVEFLGIECMKSG 1640
E+F T + +L GL++ +++ A+ V + ++ G
Sbjct: 2355 EKFMTTEVIELLASFGLKSKLGFSTLLDIARSVSLQQDDALEHG 2398
>emb|CAG09278.1| unnamed protein product [Tetraodon nigroviridis]
Length = 3392
Score = 146 bits (369), Expect = 5e-33
Identities = 189/816 (23%), Positives = 331/816 (40%), Gaps = 104/816 (12%)
Query: 114 PKDENSLIDDVDLFMSSLINDMVEEEFWSELKLITWCPVILDPAVRGLPWLKSSKQVALP 173
PK L +DL + + W +K+ + P P SS + P
Sbjct: 1332 PKAYRFLKSLLDLMKKHMNECGEDSSHWETIKMTKFLPAFC-------PGHTSSVTLERP 1384
Query: 174 TVVRPKSQMWLVSSSMLILDGEC----GTTYLQTKLGWMDCPNIGVLSRQLIELSKSYQQ 229
T + LVS + +LD T + T LG +D P+ ++ L +L KSY+Q
Sbjct: 1385 TDIFNDKCSLLVSMTQPVLDHSNLNMHNTDPVLTFLGVIDSPSPEIV---LSQLQKSYEQ 1441
Query: 230 LKTHSLLDPDFDVKLQKEIPCLYSKLQEYI-NTDDFNDLKARLDGVSWVWIGDDFVSPNA 288
++ L K Y L +Y+ + + + ++ + FV N
Sbjct: 1442 SQSTG------KAVLYKIAYECYHFLNQYLAGSVSPSSIHQAAHSFPFILVDSTFVHVNC 1495
Query: 289 LAFDSPVKFTPYLYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTD 348
+A + PYL+V+ S +K L +GV+ SF I + VLQ L + PLS
Sbjct: 1496 VAENEQFDAKPYLHVLPSSFVHFKTLWGCVGVKKSFTIQQFHTVLQELHSRYGSQPLSQR 1555
Query: 349 QLNFVRCVHEAIAECCLEKPLFEPFDSPLW---IPDTFGVLMHAGDLVYNDAPWLENSSL 405
L+ + L K + E + +P+ GVL HA +LVYND+PW+ S
Sbjct: 1556 DLSICLTI--------LNKGILEAEKETVGDCLVPNEDGVLQHARELVYNDSPWMPVPS- 1606
Query: 406 IGRHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGYN---------KVSELLAL 456
G H +I+ A G+++ R +L++ ++ K + + ++ +++
Sbjct: 1607 -GVTLCHRNIARAAALHFGIKTTRHDTLLNSEV-KSISPFAFQFEQQEQLTVRIKNIISA 1664
Query: 457 YGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFEGACLS 516
Y + + +L +LL+ AD +A ++H ++DKR+H + + QGPAL +F S
Sbjct: 1665 YPSKKDILKELLQNADDAEATEIHFVWDKRQHGVEKTFGERWNQLQGPAL-CVFNNKVFS 1723
Query: 517 REEFSNFQLL---PPWKLRGNTLNYGLGLVGCYSICDLLSVVSG-GYFYMFDPRGLVLSA 572
+ Q L RG YG+G Y + D S+++G + DP +
Sbjct: 1724 NADLKGIQQLGEGGKHSTRGKIGKYGVGFNSVYHLTDCPSILTGDSLLCISDPNQKYIEC 1783
Query: 573 PSSNAPSGKMFSLIGTDLAQRFGDQFSPMLID-QNDLWSLSDSTIIRMPLSSDCLKVGHD 631
S AP+G IG L +F + ++ + D + L + T+ R+PL + + +
Sbjct: 1784 YSDKAPAG-----IGYKLDDKFKNMYADVYQSFLPDRFPLHEGTMFRLPLRTFFMATSSN 1838
Query: 632 VASNRI-----KHITDVFMEHGSRTLLFLKSVLQVSISTWEEGHSHPCQN-FSI--SIDP 683
++ + + + +LFLK++ ++ + + S P + F++ SI P
Sbjct: 1839 ISDKEVTDSDMRMLCSALSADSDGLILFLKNITKIEVHEINDHGSKPNRTIFTVEKSIAP 1898
Query: 684 SSSIMRNPFSEKKWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLALSLGSGQ 743
+S + F + S VI + S W++A GS Q
Sbjct: 1899 TSRDQKEAFVRLR------QDALKSHTVVAPQKVIYETRVSTSDKKETTWMIAEQFGSYQ 1952
Query: 744 TRNMALDRRYLAYNLTPVAGIAALISRNGHHADVYSTSSI------MTPLPLSGCINLPV 797
+ L+ L P A +AA +S + + + S+ LPL G LPV
Sbjct: 1953 NTG---ESEMLSDQL-PQAAVAARMSITFRQSSSFLSPSVEFTGEAFCSLPLPGKTGLPV 2008
Query: 798 TVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNRELMSCVCDSYVEMILEIQ 857
+ F V R + L+K +D +++ G WN L V Y +++L I
Sbjct: 2009 HINANFEVDSAR-KNLWK-EDGQSAKSG-----------WNEFLKENVAPLYADLLLYI- 2054
Query: 858 NLRKDVSSSIIDSSACPGINLSLKAYGDNIY-SFWP 892
SS I + P L + + +++Y FWP
Sbjct: 2055 -------SSNIGNKKVP---LPYRFHLNSMYLCFWP 2080
Score = 89.7 bits (221), Expect = 8e-16
Identities = 132/628 (21%), Positives = 255/628 (40%), Gaps = 62/628 (9%)
Query: 231 KTHSLLDPDFDVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDFVSPNALA 290
K ++ DPD +V ++E+ C+Y +Q +++ DF + R W+W FVSP L
Sbjct: 443 KAEAMADPDRNVDFKRELRCIYEHMQNHMS--DFVTIVNREK--RWLWNHGRFVSPQDLV 498
Query: 291 FDSP--VKFTPYLYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDL-------- 340
+ P + + Y+ V E +K L+ + G+R + + + +L+ +Q +
Sbjct: 499 LEYPPNLDLSSYISKVPEEFLSFKKLLQRFGLRTTLSDEEIVGILRSVQQTVQERRPPFA 558
Query: 341 --NGVPLSTDQLNFVRCVHEAIAECCLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAP 398
+ + +S + LN++ + + E + P+ + P + V N+
Sbjct: 559 NPSEIKVSIEILNWLWREKKTVQED-IPVPVHTEGGQYTFKPSSTVVFCDVSKKGMNELK 617
Query: 399 WLENSSLIGRHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGYN----KVSELL 454
+ + +H I AE L + S ++ ++ C ++ +L
Sbjct: 618 SSQEEMFV----IHEEIPKAAAEWLNI-SFLSTHILDPELVGIEQCGQSEPITRRIKNIL 672
Query: 455 ALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPR--QSLLQHNLGEFQGPALVAIFEG 512
Y + +L++ A+ A++ + D R H + L+ ++ QGP L A F
Sbjct: 673 NEYDEEGDIFKELIQNAEDAGAQQCSFLVDFRTHKYNPEELIDPDMSLCQGPCLWA-FNN 731
Query: 513 ACLSREEFSNFQLL----PPWKLRGNTLNYGLGLVGCYSICDLLSVVSGGYFYMFDPRGL 568
++++N + KL +GLG Y + D+ S++SG + DP
Sbjct: 732 ETFKDDDWTNIVRVGSASKETKLE-KIGKFGLGFNTVYHVTDIPSILSGNRLLILDPNVT 790
Query: 569 VLSAP-SSNAPSGKMFSLIGTDLAQRFGDQFSPM-LIDQNDLWSLS--DSTIIRMPLSSD 624
L + G L L + F QF P I D + T+IR+P ++
Sbjct: 791 HLKTHIKQKSNPGIRLDLSQLRLFKCFPGQFGPYDRIFDCDFAKQKPYEGTLIRLPFRTE 850
Query: 625 CLKVGHDVASNRIKHITDV------FMEHGSRTLLFLKSVLQVSISTWEEGHSHPCQNFS 678
+ ++ S R+ + +D+ E+ LLFL+S+ +++ + S P ++
Sbjct: 851 EEALTSEI-SKRVYYKSDIVSFQECLAENSKSHLLFLRSISSLALQNIPKDASTPPRDDE 909
Query: 679 ISIDPSSS-----IMRNP----FSEKKWRKFQLSRLFSSSNTAIKM---HVIDVSLYSEG 726
I + S +R P S+++ + L L +N+ I +++++
Sbjct: 910 IKTIRNVSRTTVTTVRIPNRAHMSKQQESEKLLMSLDVKANSVIDYCTADIVNITSQQSS 969
Query: 727 TTFIDRWLLALSLGSGQTRNMALDRRYLAYNLTPVAGIAALISRNGHHADVYSTSSIMTP 786
T + WLL G+ Q+ MAL A P+ G+A + N + + + +
Sbjct: 970 VTEVQSWLLYSCFGTQQSVKMALQENKQAKFSLPMGGVAVPLQMNAKTNKLTTMEAEFSG 1029
Query: 787 -----LPLSGCINLPVTVLGCFLVCHNR 809
LPLS LPV++ G F V NR
Sbjct: 1030 EAFCFLPLSIHTGLPVSINGTFAVTSNR 1057
>ref|XP_417138.1| PREDICTED: similar to sacsin [Gallus gallus]
Length = 4760
Score = 136 bits (342), Expect = 7e-30
Identities = 176/748 (23%), Positives = 311/748 (41%), Gaps = 106/748 (14%)
Query: 196 CGTTYLQTK--LGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDFDVKLQKEIPCLYS 253
CG L K LG + P + ++ QL E++KS+ + + + Y
Sbjct: 2453 CGALSLAVKEFLGLLKKPAVNLVINQLEEVAKSFDGITLYQ----------ENITNACYK 2502
Query: 254 KLQEYINTDDFND--LKARLDGVSWVWIGDDFVSPNALAFDSPVKFTPYLYVVSSEL-SE 310
L E + ++ + +L S++ + + +V P ++F + PYLY + ++ +
Sbjct: 2503 HLHEAMLENESTKAMIIEQLTNCSFILVENVYVDPTKVSFHLNFEAAPYLYQLPNKYKNS 2562
Query: 311 YKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRC-----------VHEA 359
+++L +GVR SF + D+ VL+ L N G T++ NF C + E
Sbjct: 2563 FRELFESMGVRQSFTVEDFALVLE-LINQERGTKQLTEE-NFQLCRRIISEGIWSLIREK 2620
Query: 360 IAECCLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSLIGRHFVHPSISNDL 419
E C++K + +PDT L+ A L YND PW++ + + H I ++
Sbjct: 2621 KQEFCVKKY------GEILLPDTRFALLPAKSLCYNDCPWIKVKDTTVK-YCHADIPREV 2673
Query: 420 AERLGVQSVRCLSLVSEDMTKDLPCMGY---------NKVSELLALYGNSEFLLFDLLEL 470
A +LG R +L +G +++ +L Y + + +L +LL+
Sbjct: 2674 AVKLGAIPKRHKALERYASNICFTTLGTEFGQKEKLTSRIKSILNAYPSEKEMLKELLQN 2733
Query: 471 ADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSNFQLLPPWK 530
AD KA ++ ++D R+HP + QGPAL ++ + ++ Q L
Sbjct: 2734 ADDAKATEICFVFDPRQHPADRIFDEKWAPLQGPAL-CVYNNQPFTEDDIRGIQNLGKGT 2792
Query: 531 LRGN---TLNYGLGLVGCYSICDLLSVVSGG-YFYMFDPRGLVLSAPSSNAPSGKMFSLI 586
GN T YG+G Y I D S +SG +FDP +S +P G+MF +
Sbjct: 2793 KVGNPCKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSTSP-GRMFRDL 2851
Query: 587 GTDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPL-SSDCLKVGH----DVASNRIKHIT 641
D +F D L D + L + T+ R PL + + KV + ++++
Sbjct: 2852 DADFRTQFSDVLDLYL---GDHFKLDNCTMFRFPLRNGEMAKVSEISTVPCSDRMVQNLL 2908
Query: 642 DVFMEHGSRTLLFLKSVLQVSISTWEE--GHSHPCQNFSISIDPSSSIMRNPFS----EK 695
D G+ L+FL + ++SI E+ G + + I + R F +
Sbjct: 2909 DKLRTDGAELLMFLNHMEKISICEIEKTTGALNVLYSVQGKITDGDRLKRKQFHASVIDS 2968
Query: 696 KWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLALSLGSGQ----TRNMALDR 751
+K QLS + T + +D SEG + WL+ G ++++
Sbjct: 2969 VTKKKQLSEIPVQQIT----YTMDTE-DSEGN--LTTWLICNRSGFSAMEKVSKSVVSAH 3021
Query: 752 RYLAYNLTPVAGIAALISRN---GHHADVYSTSSIMTPLPLSGCINLPVTVLGCFLVCHN 808
+ L P G+AA I+ N H A + LPLS LP V G F +
Sbjct: 3022 KNEDITLFPRGGVAACITHNYKKPHRAFCF--------LPLSLETGLPFHVNGHFALDSA 3073
Query: 809 RGRYLFKYQDRRASAEGHFDAGNQLIELWNRELMSC-VCDSYVEMILEIQNL---RKDVS 864
R R L++ D G + WN LM+ + +YVE++++++ D +
Sbjct: 3074 R-RNLWR-----------DDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGTDPT 3121
Query: 865 SSIIDSSACPGINLSLKAYGDNIYSFWP 892
S++ ++ + +LK + SF+P
Sbjct: 3122 VSVLQNTPVHAVKDTLKKF----LSFFP 3145
Score = 72.8 bits (177), Expect = 1e-10
Identities = 109/476 (22%), Positives = 191/476 (39%), Gaps = 57/476 (11%)
Query: 450 VSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAI 509
+ ++L Y +L +L++ A+ A ++ +YD+ ++ ++L ++ ++QGPA A
Sbjct: 272 LKDILRRYPEGGQILKELIQNAEDAGATEVRFLYDETQYGTETLWSKDMAQYQGPAFYA- 330
Query: 510 FEGACLSREEFSNFQLLPPWKLRGNTL---NYGLGLVGCYSICDLLSVVSGGYFYMFDPR 566
+ A + E++ Q + + + + L +G+G Y I D+ S+ SG M DP
Sbjct: 331 YNDAIFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPSIFSGDQIGMLDPH 390
Query: 567 GLVLSAPSSNAPSGKMFSL-IGTDLAQRFGDQFSPML-----IDQNDLWSLSDSTIIRMP 620
+ SG+ ++L + DQF+P + + T R P
Sbjct: 391 QTLFGPHE----SGQCWNLKEDSKEINELTDQFAPFIGVFGSTKETFKNGNFPGTFFRFP 446
Query: 621 LSSDCLKVGHDV-ASNRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEEGHSHPCQNFSI 679
L ++ +V ++ + + F LLFLKSV VS+ E + F +
Sbjct: 447 LRLQPSQLSSNVYDKQKVLELFESFRADADTVLLFLKSVQDVSLHVREADGTEKL-IFRV 505
Query: 680 SIDPSSSIMRNPFSEKKWRKFQLSR----LFSSSNTAIKMHVIDVSLYSEGTTFIDR--W 733
+ + ++ + K +++ + S+S T + HV +++L E + W
Sbjct: 506 TASENKALKHERPNSIKILGTAINQYCKGVPSNSITCVTYHV-NIALEDESVKDAQKTSW 564
Query: 734 LLALSLGSGQTRNMALDRRYLAYNL--TPVAGIAALISRN----GHHADVYSTSSIMTPL 787
L+ +G R M + LA +L P GIA +S N G AD + PL
Sbjct: 565 LVCNCVGG---RGMCTELDCLADDLKFVPTIGIAMPLSYNEKDKGAVADFSGRAFCFLPL 621
Query: 788 P--LSGCINLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNREL-MSC 844
P LPV V G F + N RR+ D LWN L ++
Sbjct: 622 PPGEESKTGLPVHVSGFFGLTDN----------RRSIKWRELDQWRDPAALWNDLLVVNI 671
Query: 845 VCDSYVEMILEIQNLRKDVSSSIIDSSACPGINLSLKAYGDNIYSFWPRSSEGHVP 900
V +Y +ILE + +S SA + IY WP ++ VP
Sbjct: 672 VPKAYSTLILEAIKRMETEENSDFPLSA------------ERIYGLWPDENKIRVP 715
Score = 54.3 bits (129), Expect = 4e-05
Identities = 58/279 (20%), Positives = 109/279 (38%), Gaps = 45/279 (16%)
Query: 1442 AQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPSNSFFKPHDEHCLSYATDSNGSSFLR- 1500
+Q++I+IL+SLP YK++ G Y + C + + S P E + T S S+FL
Sbjct: 3581 SQDDIKILKSLPCYKSISGRYISISKYGTCYVLTKSI--PSVE--VDRWTQSTSSAFLEE 3636
Query: 1501 ---------ALGVLELNDQQILVRFGLPGYERKSMNEQEDILIYVFKNWHDLQSNQSVVE 1551
LG + ++D ++ ++ LP E S + + + LIY+ ++ + E
Sbjct: 3637 KIHLKDLYTVLGCVSVDDLEVYLKHLLPKIESLSYDAKLEHLIYLKNRLSSIEETSEMKE 3696
Query: 1552 ALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKKFPGERFS----------- 1600
L E +++ LKP + F + + E+ P + F
Sbjct: 3697 QLFEKLESILIIHDASNRLKPAKYFYDRTVKVFEVMLPEKLFIPQDFFKKLEQITKPKSQ 3756
Query: 1601 ---TDGWLRILRKLGLRTATEVDVIIECAKRVEFLGIECMKSGDLDDFEADTTNSRAEVS 1657
W+ LR +GL+ +++ AK + + +++ +T + +V
Sbjct: 3757 AAFLPSWVTFLRHIGLKYIISQQQLLQFAKEISM-------RANTENWSKETLQNAVDV- 3808
Query: 1658 PEVWALGGSVVEFIFSNFALFFSNNFCDLLGKIAFVPSE 1696
++ IF S NF L I F+ E
Sbjct: 3809 ---------LLHHIFQERTDLLSGNFLKELSLIPFLCPE 3838
Score = 48.5 bits (114), Expect = 0.002
Identities = 36/122 (29%), Positives = 65/122 (52%), Gaps = 7/122 (5%)
Query: 1525 SMNEQEDILIYVFKNWHDLQS-NQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAIL 1583
S +E I+ +V +N L++ N V++ L +F+R S+E L+ ELFDP +L
Sbjct: 1184 SYDETTQIMQWVLENLTFLKNENTDVIDWLAALRFIRISEE---KLMTANELFDPEVELL 1240
Query: 1584 ISIFFGERK-KFPGERFSTDGWLRILRKLGLRTATEVDV--IIECAKRVEFLGIECMKSG 1640
++F+ E + FP F++ L LR++GL++ ++ I+ A ++E L +
Sbjct: 1241 QNLFYSEEEISFPPAIFTSSDILHSLRQIGLKSEANLEESDIMRVANKIESLHADSNTDC 1300
Query: 1641 DL 1642
DL
Sbjct: 1301 DL 1302
Score = 48.1 bits (113), Expect = 0.003
Identities = 125/617 (20%), Positives = 223/617 (35%), Gaps = 138/617 (22%)
Query: 1 LYDPRVPELKKMLHGD--VFFPSDKFLDPEILDTLVCLGLRT--TLGFTGLLDCARSVSL 56
L+DP V L+ + + + + FP F +IL +L +GL++ L + ++ A +
Sbjct: 1232 LFDPEVELLQNLFYSEEEISFPPAIFTSSDILHSLRQIGLKSEANLEESDIMRVANKIES 1291
Query: 57 LHDSGDTEAS---KHGKGLLVFLDKLACKLSSNGESENDDQSLAVRSNITMDDAVVYDGF 113
LH +T+ + + LL+ L+K L S+
Sbjct: 1292 LHADSNTDCDLLVRKARTLLMILNKNHKLLQSS--------------------------- 1324
Query: 114 PKDENSLIDDVDLFMSSLINDMVEEEFWSELKLITWCPVILD--PAVRG-LPWLKSSKQV 170
E + LK I W P + P G L W +
Sbjct: 1325 -------------------------ETKTALKKIKWIPACKERPPNYPGSLVWKGDHCNL 1359
Query: 171 ALPTVVRPKSQMWLVSSSMLILDGECGTTYLQTKLGWMDCPNIGVLSRQLIELSKSYQQL 230
LP + S LV SS+ +++ ++ LG P+I + + ++ +
Sbjct: 1360 CLPPEMCDISHAILVGSSVPLVENV--QFDIEKALGISTKPSIKAVLKHF-KVVVDWHSS 1416
Query: 231 KTHSLLDPDFDVKLQKEIPCLYSKLQEYINT--DDFNDLKARLDGVSWVWIGDDFVSPNA 288
KT S D D+ + Q + +Y + +++ + F LK WVW G F S
Sbjct: 1417 KTFS--DEDY-YQFQHILLEIYGFMHDHLEEGKEAFKALK-----FPWVWTGKTFCSLTQ 1468
Query: 289 LAFDS--PVKFTPYLYVVSSELSEYKDLM------------------------------- 315
+ + PYL+ V ++++ L
Sbjct: 1469 AVIKTVPDLDLQPYLHYVPKTMAKFHQLFKCCGSIEQLTPDHVSMVIQKIYLKSEQSLSE 1528
Query: 316 --IKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCVHEAIAECCLEKPLFEPF 373
K + + I+ +L+ Q + +PL + +L + + V I ECC +
Sbjct: 1529 QESKQNLHIMLSIIRWLYSNQIPASLHTPMPLYSGKLPY-KLVMRPIHECCYCDIKVDDL 1587
Query: 374 DSPLWIPDTFGVLMHAGDLVYNDAPWLENSSLIGRHFVHPSISNDLAERLGVQSVRCLSL 433
+ L +L+H D+ A WL N + ++P E +G + S
Sbjct: 1588 NDLLEDSVEPIILVHE-DIPMKTAEWL-NVPCLSTRLINP-------ENMGFEQ----SG 1634
Query: 434 VSEDMTKDLPCMGYNKVSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHP--RQ 491
E +T ++ +L Y + + +LL+ AD A + + + D R + R+
Sbjct: 1635 QREPLTV--------RIKNILEEYPSISDIFKELLQNADDANASECNFLIDMRRNMDIRE 1686
Query: 492 SLLQHNLGEFQGPALVAIFEGACLSREEFSNFQLLPPWKLRGNTLN---YGLGLVGCYSI 548
+LL + GPAL + F + S +F N L R +GLG Y I
Sbjct: 1687 NLLDPGMAACHGPALWS-FNNSEFSDSDFLNITRLGESLKRSEVDKVGKFGLGFNSVYHI 1745
Query: 549 CDLLSVVSGGYFYMFDP 565
D+ ++S + MFDP
Sbjct: 1746 TDVPIILSREFMIMFDP 1762
Score = 46.2 bits (108), Expect = 0.010
Identities = 40/168 (23%), Positives = 75/168 (43%), Gaps = 11/168 (6%)
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWI--GDDFVSPNALAFDSPVK-- 296
D ++ K + + E+++T+ + + +L GVS+V + G + P + + +
Sbjct: 3943 DEEMVKTRAKILRSIYEFLSTEK-REFRFQLRGVSFVMVEEGWKLLKPEEVVINLEYESD 4001
Query: 297 FTPYLYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCV 356
F PYLY + EL + L LG Y+ VL R+ + G L +++ V+ V
Sbjct: 4002 FKPYLYKLPLELGTFHQLFKHLGTEDVISTKQYVEVLGRIFKNSEGKQLDPNEMRTVKRV 4061
Query: 357 HEAIAECC------LEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAP 398
+ + + L D L++P G L+ + LV++DAP
Sbjct: 4062 VSGLFKSLQNDSVKVRNDLENMRDFALYLPSQDGRLVKSSILVFDDAP 4109
>ref|XP_534533.1| PREDICTED: similar to sacsin [Canis familiaris]
Length = 4723
Score = 130 bits (326), Expect = 5e-28
Identities = 183/816 (22%), Positives = 330/816 (40%), Gaps = 104/816 (12%)
Query: 132 INDMVEEEFWSELKLITWCPVILDPAVRGLPW----LKSSKQVALPTVVRPKSQMWLVSS 187
I D ++F + + I + P + PA L W K A + + Q +
Sbjct: 2366 IRDPRAKDFAARYQTIPFLPFLTKPAGFSLDWKGNSFKPETMFAAIDLYTAEHQDIVCLL 2425
Query: 188 SMLILDGE-----CGTTYLQTK--LGWMDCPNIGVLSRQLIELSKS-------YQQLKTH 233
++ + CG+ L K LG + P + ++ QL E++KS YQ+ T+
Sbjct: 2426 QPILNENSHSFRGCGSVSLAVKEFLGLLRKPTVDLVVNQLKEVAKSVDDGVTLYQENITN 2485
Query: 234 SLLDPDFDVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDFVSPNALAFDS 293
+ D +Q E+ + + +L S++ + + +V ++F
Sbjct: 2486 ACYKYLHDAMMQNEMIKI--------------SIIEKLKPFSFILVENAYVDSEKVSFHL 2531
Query: 294 PVKFTPYLYVVSSEL-SEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNF 352
+ PYLY + ++ + +++L +GVR SF + D+ VL+ + + G T++ NF
Sbjct: 2532 NFEAAPYLYQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQE-KGTKQITEE-NF 2589
Query: 353 VRC---VHEAIAECCLEKP--LFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSLIG 407
C + E I EK E + +PDT L+ A L YND PW++
Sbjct: 2590 QLCRRIISEGIWSLIREKKQEFCEKNYGKILLPDTNLKLLPAKSLCYNDCPWIKVKDTTV 2649
Query: 408 RHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGY---------NKVSELLALYG 458
+ + H I ++A +LG R +L +G +++ +L Y
Sbjct: 2650 K-YCHADIPREVAVKLGAVPKRHKALERYASNICFTTLGTEFGQKEKLTSRIKSILNAYP 2708
Query: 459 NSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFEGACLSRE 518
+ + +L +LL+ AD KA ++ ++D R+HP + QGPAL ++ + +
Sbjct: 2709 SEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPAL-CVYNNQPFTED 2767
Query: 519 EFSNFQLLPPWKLRGN---TLNYGLGLVGCYSICDLLSVVSGG-YFYMFDPRGLVLSAPS 574
+ Q L GN T YG+G Y I D S +SG +FDP +
Sbjct: 2768 DVRGIQNLGKGTKEGNPCKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGAT 2827
Query: 575 SNAPSGKMFSLIGTDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPLSSDCLKVGHDVAS 634
S +P G+MF + D +F D L + L + T+ R PL + + +++S
Sbjct: 2828 SVSP-GRMFRDLDADFRTQFSDVLDLYL---GTHFKLDNCTMFRFPLRNAEMAKVSEISS 2883
Query: 635 -----NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEEGHSHPCQNFSI--SIDPSSSI 687
++++ D G+ L+FL + ++SI ++G +S+ I +
Sbjct: 2884 VPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKGTGALNVLYSVKGKITDGDRL 2943
Query: 688 MRNPFSEKKWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLALSLGSGQ---- 743
R F R + +D SEG + WL+ G
Sbjct: 2944 KRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTE-DSEGN--LTTWLICNRSGFSSMEKV 3000
Query: 744 TRNMALDRRYLAYNLTPVAGIAALISRN---GHHADVYSTSSIMTPLPLSGCINLPVTVL 800
++++ + L P G+AA I+ N H A + LPLS LP V
Sbjct: 3001 SKSVISAHKNQDITLFPRGGVAACITHNYKKPHRAFCF--------LPLSLETGLPFHVN 3052
Query: 801 GCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNRELMSC-VCDSYVEMILEIQNL 859
G F + R R L++ D G + WN LM+ + +YVE++++++
Sbjct: 3053 GHFALDSAR-RNLWR-----------DDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKR 3100
Query: 860 ---RKDVSSSIIDSSACPGINLSLKAYGDNIYSFWP 892
D + S++ ++ + +LK + SF+P
Sbjct: 3101 YFPGSDPTLSVLQNTPIHVVKDTLKKF----LSFFP 3132
Score = 115 bits (287), Expect = 2e-23
Identities = 270/1288 (20%), Positives = 488/1288 (36%), Gaps = 252/1288 (19%)
Query: 450 VSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQG------ 503
+ ++L Y +L +L++ A+ A ++ +YD+ ++ ++L ++ ++QG
Sbjct: 161 LKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAQYQGIFSGGL 220
Query: 504 ------------------PALVAIFEGACLSREEFSNFQLLPPWKLRGNTL---NYGLGL 542
PAL ++ A + E++ Q + + + + L +G+G
Sbjct: 221 ELAGPDTVHQMPLSTGCRPALY-VYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGF 279
Query: 543 VGCYSICDLLSVVSGGYFYMFDPRGLVLSAPSSNAPSGKMFSL-IGTDLAQRFGDQFSPM 601
Y I D+ + SG M DP + SG+ ++L + DQF+P
Sbjct: 280 NSVYHITDVPCIFSGDQIGMLDPHQTLFGPHE----SGQCWNLKDDSKEISELSDQFAPF 335
Query: 602 L-----IDQNDLWSLSDSTIIRMPLSSDCLKVGHDVAS-NRIKHITDVFMEHGSRTLLFL 655
+ + + + T R PL ++ ++ + ++ + D F LLFL
Sbjct: 336 IGIFGSTKETFVNANFPGTFFRFPLRLQPSQLSSNLYNKQKVLELFDSFRADADTVLLFL 395
Query: 656 KSVLQVSISTWEEGHSHPCQNFSISIDPSSSIMRNPFSEKKWRKFQLS----RLFSSSNT 711
KSV VS+ E + F ++ + ++ + K + +S ++ S+S T
Sbjct: 396 KSVQDVSLHVREADGTEKLV-FRVTASENKALKHERPNSVKILETAISNYCKKIPSNSIT 454
Query: 712 AIKMHVIDVSLYSEGTTFIDR--WLLALSLGSGQTRNMALDRRYLAYNLTPVAGIAALIS 769
+ H I++ L E T + WL+ S+G G+ + LD P+ GIA +S
Sbjct: 455 CVTYH-INIVLEDESTKDAQKTSWLVCNSVG-GRGISGKLDSLADELKFVPIIGIAMSLS 512
Query: 770 RN----GHHADVYSTSSIMTPLP--LSGCINLPVTVLGCFLVCHNRGRYLFKYQDRRASA 823
R+ G AD + PLP LPV + G F + N RR+
Sbjct: 513 RDDEEKGATADFSGKAFCFLPLPPGEESKTGLPVHISGFFGLTDN----------RRSIK 562
Query: 824 EGHFDAGNQLIELWNREL-MSCVCDSYVEMILE-IQNLRKDVSSSIIDSSACPGINLSLK 881
D LWN L M+ V +Y +IL+ I+ L + SS LS+
Sbjct: 563 WRELDQWRDPAALWNEFLVMTVVPKAYATLILDSIKRLETERSSD---------FPLSV- 612
Query: 882 AYGDNIYSFWPRSSEGHVPSGQLFDHNNTPSSSTAVLKADWECLKERVIHPFYSRIVDLP 941
D IY WP S+ ++ W + V+ P ++ +
Sbjct: 613 ---DLIYKLWPDVSK---------------------VRVHW----QPVLEPLFNELFQNA 644
Query: 942 VWQLYSGNLVKAGEGMFLSQPGNGMIGSLLPGTVCSFVKEHYPVFSVPWELVTEIQVVGF 1001
V S VK + F + + + S K + VP L +Q+
Sbjct: 645 VMYSLSNQWVKLEQAYFSELDESWECTKSVLSYLQSSGKH---IVKVPPNLAAAVQLAAS 701
Query: 1002 S---VREVRPKMVRDLLKVSSKPIVLRSVDMYIDVLEYCLSNFQQSVPSSLPRDSAQVDP 1058
S VR+V P VR +L+ S+ P + +LE+ LS D A +
Sbjct: 702 SAKPVRKVTPAWVRQVLRKSAHP---GGAQDKLHLLEFVLS------------DQAYSEL 746
Query: 1059 TNINVICRETDVGSTSQPESNIHSSTGIASQGADSSGDALEMMTSLGKVLIDFGRGVVED 1118
+ ++ + + + + S D + + + D+ R +
Sbjct: 747 LGLELL--------------PLQNGNFVPFSSSVSDQDVIYITSE------DYPRSLFPG 786
Query: 1119 IGRAGAPLAYRNAVTGTGQNRDQKFVSIAAELKGLPCPTATNHLQKLGLTELWIGNKEQQ 1178
+ + + + + Q V I A GL P NH + LT L G E
Sbjct: 787 LEGRFILDSLKPHLIAALKEAAQTRVEIMAGDSGLLLPLIQNHPDQ--LTGLCTGRVEDS 844
Query: 1179 --SLMDPLREKFVHPKVLERPLLGE----IFSNLSLQGLLKL-----QNFSLHLLANHMK 1227
S M P V + P L +F L ++ ++ L Q + ++
Sbjct: 845 RLSYMGPALHSAVWGRTPPPPRLPRNVQILFLKLPVRSVIPLSDGVGQMEGMRRPCTQLQ 904
Query: 1228 LIFHEDWVNHVMGSNMAPW----LSWKKLPSSDSQGGPSSEWIKIFWKS-FRGSQEELSL 1282
L+ E + + W L + P + + PS W+K+ WK+ + E+L+L
Sbjct: 905 LLNPERFARLIKEVMNTFWPGRELIVQWYPFDEDKNHPSVSWLKMVWKNLYIHFSEDLTL 964
Query: 1283 FSDWPLIPAFL---GRPVLCRVRERHLVFIPPPLVQRTLQSGILDRESTE---------- 1329
F + PLIP G+ + +R R P LV ILD ES
Sbjct: 965 FDEMPLIPRTTLEEGQTCMELIRLR-----IPSLV-------ILDDESEAQLPEFLADIV 1012
Query: 1330 NHVGGVSVSRDDTSVAEAYTSAFDRLKISYPWLLSLLNQCNVPIFDEAFIDCATSSNCFS 1389
+GG+ + + D S+ + + S L + I ++
Sbjct: 1013 QKLGGIVLKKLDASIQHPLIKKY---------IHSPLPSAVLQIMEK------------- 1050
Query: 1390 MPGGSLGQVIASKLVAAKQAGYFTEPNNLSASSCDALFSLFCDELFSNGFHYAQEEIEIL 1449
MP L IAS L K A AS D+ +++E I+
Sbjct: 1051 MPLQKLCNQIASLLPTHKDA-----LRKFLASLTDS----------------SEKEKRII 1089
Query: 1450 RSLPIYKTV-------VGSYTKLKDQDQCMIPSNSFFKPHDEHCLSYATDSNGSSFLRAL 1502
+ LPI+K + + SYTKLK C + ++ D DS+ + +R
Sbjct: 1090 QELPIFKRINHLSDQGISSYTKLKG---CKVLHHTAKLAPDLRLSISVIDSSDEATIRLA 1146
Query: 1503 GVLELNDQQI--LVRFGLPGYERK--SMNEQEDILIYVFKNWHDLQS-NQSVVEALKETK 1557
+L++ + ++ L E S +E +++++ +N L++ N +V++ L K
Sbjct: 1147 NMLKIEKLKTTHCIKLILRDIENAFYSHDEVTHLMLWILENLSSLKNENPNVLDWLMPLK 1206
Query: 1558 FVRNSDEFSTDLLKPKELFDPADAILISIFFGERKK-FPGERFSTDGWLRILRKLGLRTA 1616
F++ S E ++ ELFDP +L +F+ E + FP F++ L LR++GL+
Sbjct: 1207 FIQISQE---QMVSAGELFDPDIEVLKDLFYNEEETCFPPSVFTSPDILHSLRQIGLKNE 1263
Query: 1617 TEV--DVIIECAKRVEFLGIECMKSGDL 1642
+ + +++ AK++E L + + D+
Sbjct: 1264 ASLKENDVVQVAKKIEDLQVSSCPNQDI 1291
Score = 49.7 bits (117), Expect = 0.001
Identities = 49/218 (22%), Positives = 93/218 (42%), Gaps = 40/218 (18%)
Query: 1442 AQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPSNSFFKPHDEHCLSYATDSNGSSFL-- 1499
+Q++I+IL+SLP YK++ G Y + C + + S P E + T S+ S+FL
Sbjct: 3568 SQDDIKILKSLPCYKSISGRYMSIAKFGTCYVLTKSI--PSAE--VEKWTQSSLSAFLEE 3623
Query: 1500 --------RALGVLELNDQQILVRFGLPGYERKSMNEQEDILIYVFKNWHDLQSNQSVVE 1551
LG + ++D ++ ++ LP E S + + + LIY+ ++ + E
Sbjct: 3624 KIHLKELYEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLSSIEELSEIKE 3683
Query: 1552 -----------------ALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERK-- 1592
LK+ K + +++ P++LF P D FF + +
Sbjct: 3684 QLFEKLESLLIIHDANSRLKQAKHFYDRTVRVFEVMLPEKLFIPKD------FFKKLEQL 3737
Query: 1593 -KFPGERFSTDGWLRILRKLGLRTATEVDVIIECAKRV 1629
K + W+ LR +GL+ +++ AK +
Sbjct: 3738 IKPKNQATFMTSWVEFLRNIGLKYILSQQQLLQFAKEI 3775
Score = 45.8 bits (107), Expect = 0.013
Identities = 105/468 (22%), Positives = 176/468 (37%), Gaps = 81/468 (17%)
Query: 144 LKLITWCPVILD--PAVRG-LPWLKSSKQVALPTVVRPKSQMWLVSSSMLILDGECGTTY 200
LK I W P + P G L W + P + + LV SS+ ++ E
Sbjct: 1319 LKKIKWVPACKERPPNYPGSLVWKGDVCNLCAPPDMCDGAHAILVGSSLPLV--ESVHIN 1376
Query: 201 LQTKLGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDFDVKLQKEIPCLYSKLQEYIN 260
L+ LG P+I + + ++ + KT S D D+ + Q + +Y + ++++
Sbjct: 1377 LEKALGIFTKPSISAVLKHF-KIVVDWYTSKTFS--DEDY-YQFQHILLEIYGFMHDHLS 1432
Query: 261 T--DDFNDLKARLDGVSWVWIGDDFVSPNALAFDSP---VKFTPYLYVVSSELSEYKDLM 315
D F LK WVW G F P A A P + PYL+ V ++++ L
Sbjct: 1433 EGKDAFRALK-----FPWVWTGKKFC-PLAQAVIKPFHDLDLQPYLHSVPKTMAKFHQLF 1486
Query: 316 ---------------------------------IKLGVRLSFGILDYLHVLQRLQNDLNG 342
K + L I+ +L+ Q +
Sbjct: 1487 KVCGSIEELTSDHISMVIQKVYLKSDQDLSDQESKQNLHLMLNIIRWLYSNQIPASPNTP 1546
Query: 343 VPLSTDQLNFVRCVHEAIAECCLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLEN 402
VP+ + N + + + I ECC + + L +L+H D+ A WL+
Sbjct: 1547 VPIHHSK-NPSKLIMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHE-DIPMKTAEWLKV 1604
Query: 403 SSLIGRHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGYNKVSELLALYGNSEF 462
L R ++P E +G + S E +T ++ +L Y +
Sbjct: 1605 PCLSTR-LINP-------ENMGFEQ----SGQREPLTV--------RIKNILEEYPSVSD 1644
Query: 463 LLFDLLELADCCKAKKLHLIYDKREHP--RQSLLQHNLGEFQGPALVAIFEGACLSREEF 520
+ +LL+ AD A + + D R + R++LL + GPAL + F + S +F
Sbjct: 1645 IFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWS-FNNSQFSDSDF 1703
Query: 521 SNFQLLPPWKLR---GNTLNYGLGLVGCYSICDLLSVVSGGYFYMFDP 565
N L R +GLG Y I D+ ++S + MFDP
Sbjct: 1704 VNITRLGESLKREEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDP 1751
Score = 44.7 bits (104), Expect = 0.029
Identities = 38/168 (22%), Positives = 75/168 (44%), Gaps = 11/168 (6%)
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDF--VSPNALAFDSPVK-- 296
D ++ K + + E+++ + + + +L GV++V + D + + P + + +
Sbjct: 3930 DEEMVKTRAKVLRSIYEFLSAEK-REFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYESD 3988
Query: 297 FTPYLYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCV 356
F PYLY + EL + L LG Y+ VL R+ + G L +++ V+ V
Sbjct: 3989 FKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRV 4048
Query: 357 HEAIAECC------LEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAP 398
+ + + L D L++P G L+ + LV++DAP
Sbjct: 4049 VSGLFKSLQNDSVKVRSDLENVRDLALYLPSQDGRLVKSSILVFDDAP 4096
>emb|CAG02848.1| unnamed protein product [Tetraodon nigroviridis]
Length = 4658
Score = 130 bits (326), Expect = 5e-28
Identities = 188/846 (22%), Positives = 344/846 (40%), Gaps = 119/846 (14%)
Query: 138 EEFWSELKLITWCPVILDPAVRGLPWLKSSKQVALPTVVRP----KSQMWLVSSSMLILD 193
EE L+ I + P + PA LPW ++ A R + Q + ++ +
Sbjct: 2284 EESLERLQDIKFLPFLTRPAGFSLPWHGNNFSPATLFSARELFTSEHQDTVCLMKPILNE 2343
Query: 194 GE-----CGTTYLQTK--LGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDFDVKLQK 246
CGT L K LG + P++ ++ QL +LS+S+ + + +
Sbjct: 2344 NSPSFRGCGTVSLAVKDGLGLIRTPSVELVISQLKKLSQSFDGVTLYQ----------EN 2393
Query: 247 EIPCLYSKLQEYINTDDF--NDLKARLDGVSWVWIGDDFVSPNALAFDSPVKFTPYLYVV 304
Y L E + D+ + L + + + + +VSP +AF +P+LY +
Sbjct: 2394 ITNACYKFLHEEMLQDERAKQQMAEELTAFNSILVENTYVSPAKIAFHLNFDASPHLYQL 2453
Query: 305 SSEL-SEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVR-CVHEAIAE 362
++ + ++L +GV+ SF + D+ +L+ ++ LS D R + E I
Sbjct: 2454 PNKYRNSCRELFESVGVKSSFSVEDFSGILETVKQGCGRRALSEDNFQLCRRVISEGIWS 2513
Query: 363 CCLEKPL--FEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSLIGRHFVHPSISNDLA 420
+K + S + +PD+ L + L YND PW++ + + H I ++A
Sbjct: 2514 LIRDKSQEHCKEHHSGILLPDSNLTLQPSKSLCYNDCPWIKVRDTTVK-YCHGDIPREVA 2572
Query: 421 ERLGVQSVR--CLSLVSEDMTKDLPCMGY-------NKVSELLALYGNSEFLLFDLLELA 471
+LG R L + ++ P + +++ +L+ Y + + +L +LL+ A
Sbjct: 2573 VKLGAVPKRHKALERYASNICFTPPGSEFGQKETLTSRIKSILSAYPSEKEMLKELLQNA 2632
Query: 472 DCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSNFQLLPPWKL 531
D KA +++ IYD R HP + QGPAL ++ + ++ Q L
Sbjct: 2633 DDAKATEIYFIYDPRTHPTDRVFDDKWIPMQGPAL-CVYNNQPFTEDDVRGIQNLGRGTK 2691
Query: 532 R---GNTLNYGLGLVGCYSICDLLSVVSGG-YFYMFDPRGLVLSAPSSNAPSGKMFSLIG 587
G T YG+G Y I D S +S +FDP +S +P G+MF I
Sbjct: 2692 EANPGKTGQYGIGFNSVYHITDCPSFISNNDILCIFDPHAQYAPGATSASP-GRMFRDID 2750
Query: 588 TDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPLSSDCLKVGHDVAS-----NRIKHITD 642
+D +F D + + + N + L ST+ R P+ S + +++S ++++ D
Sbjct: 2751 SDFRSQFSDVLN-LYLGAN--FKLERSTMFRFPIRSTEMAKTSEISSVPASDRMVQNLLD 2807
Query: 643 VFMEHGSRTLLFLKSVLQVSISTWEEGHSHPCQNFSIS--IDPSSSIMRNPFS----EKK 696
G+ L+FL + ++SI ++ P +S++ I + R F +
Sbjct: 2808 KLKSDGAELLMFLNHMEKISICEIDQSSGQPRVIYSVTARISDGDRLKRKQFHASVIDSV 2867
Query: 697 WRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLALSLGSGQTRNM--ALDRRYL 754
+K LS + M ++D TT W++ G N+ AL +
Sbjct: 2868 MKKKPLSAI-PVQQITYSMDILDTD--GNSTT----WMICNRSGFPNIENVSKALVSAHK 2920
Query: 755 AYNLT--PVAGIAALISRN---GHHADVYSTSSIMTPLPLSGCINLPVTVLGCFLVCHNR 809
++T P G+AA +S N H A + LPLS LP V G F + R
Sbjct: 2921 NEDITLFPRGGVAACVSHNYKKPHRAFCF--------LPLSLETGLPFHVNGHFALDSAR 2972
Query: 810 GRYLFKYQDRRASAEGHFDAGNQLIELWNRELMS-CVCDSYVEMILEIQNL---RKDVSS 865
R L++ D G + WN LM+ + + VE++++++ D +
Sbjct: 2973 -RNLWR-----------DDNGVGVRSDWNTNLMTLLIAPACVELLIQLKRRYFPGPDPTM 3020
Query: 866 SIIDSSACPGINLSLKAYGDNIYSFWPRSSEGHVPSGQLFDHNNTPSSSTAVLKADWECL 925
+I+ + + +L+ Y F+P ++ ++ DW CL
Sbjct: 3021 TILQGTPLHAVKDTLRKY----LFFFP--------------------ANRLDIQPDWYCL 3056
Query: 926 KERVIH 931
+ V H
Sbjct: 3057 VKAVYH 3062
Score = 65.9 bits (159), Expect = 1e-08
Identities = 59/228 (25%), Positives = 105/228 (45%), Gaps = 15/228 (6%)
Query: 450 VSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAI 509
+ ++L Y +L +L++ A+ A ++ +YD+ EH +SL +L + QG AL A
Sbjct: 196 LKDILRRYPEGGQILKELIQNAEDAGATEVKFMYDETEHGVESLWSPDLEQHQGTALYA- 254
Query: 510 FEGACLSREEFSNFQLLPPWKLRGNTL---NYGLGLVGCYSICDLLSVVSGGYFYMFDPR 566
+ A + E++S Q + + R + L +G+G Y + D+ S+ SG M DP
Sbjct: 255 YNDAVFTLEDWSGIQEIARSRKRDDPLKVGRFGIGFNSVYHVTDVPSIFSGDQIAMLDPH 314
Query: 567 GLVLSAPSSNAPSGKMFSL-IGTDLAQRFGDQFSPML----IDQNDLWSLS-DSTIIRMP 620
+ SG+ ++L T DQF+P I + + S T+ R P
Sbjct: 315 QTLFGPHE----SGQCWNLKTDTKEIAELSDQFAPYFGIFGISEKHMKDASFPGTLFRFP 370
Query: 621 LSSDCLKVGHDVAS-NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWE 667
L ++ +V + ++ + + F LLFLKSV ++S+ E
Sbjct: 371 LRLRPSQLSSNVYNKEKVLELFESFKADADTVLLFLKSVNRISLHVRE 418
Score = 48.1 bits (113), Expect = 0.003
Identities = 118/576 (20%), Positives = 217/576 (37%), Gaps = 93/576 (16%)
Query: 142 SELKLITWCPVILDPAVRGLPWLKSSKQVALPTVVRPKSQMWLVSSSMLILDGECGTTYL 201
S L + W PV + R L + KS V + S+M ++ ++L+ G
Sbjct: 1227 SALLKLQWVPVCKE---RPLTYPKSLSWVGDVATICSLSEMCDIAHAVLV--GSAVALVE 1281
Query: 202 QTKLGWMDCPNIGVLSR--QLIELSKSYQQLKTHSLLDPDFDVKLQKEIPCLYSKLQEYI 259
T G + V + Q+I+ K+ + + + Q+ + +Y +Q ++
Sbjct: 1282 HTSAGMRKALKLNVEPQVDQVIQHLKAVIEWHKSQAFTTEDWYQFQQILFEMYGFMQTHL 1341
Query: 260 NTDDFNDLKARLDGV--SWVWIGDDFVSPNALAFDS--PVKFTPYLYVVSSELSEYKDLM 315
D K + + WVW G F SP+ + PYLY + + ++ L
Sbjct: 1342 Q-----DAKEAMKSLPFDWVWTGKTFSSPDRTVLKPLPDLDLQPYLYSLPKTIRKFNKLF 1396
Query: 316 IKLGVRLSFGILDYLHVLQRLQNDLNG-------------------------VPLSTDQL 350
G L V+ +Q G +P++TD +
Sbjct: 1397 KSCGSIEEVDPSQVLEVVNTIQQRCTGEMTKDDSKHNILLLINILRWLYNNQIPVATD-M 1455
Query: 351 NFVRCVHEAIAECCLEKPLFEPFDSPLWIPDTFGVLMHAGD---LVYNDAP-----WLEN 402
+ H+ + + +P+ E + + D +L + LV++D P WL+
Sbjct: 1456 HVPILFHKDPSRLAM-RPIHECTYCDIKVDDLIDLLEDTSEPIVLVHDDIPMRTAEWLKV 1514
Query: 403 SSLIGRHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGYNKVSELLALYGNSEF 462
L R V+P E LG + S E +T ++ +L Y +
Sbjct: 1515 PCLSTR-LVNP-------ENLGFEQ----SGQREPLTV--------RIKNILEEYPSVAD 1554
Query: 463 LLFDLLELADCCKAKKLHLIYDKREHP--RQSLLQHNLGEFQGPALVAIFEGACLSREEF 520
+ +LL+ AD A + + + D R++ R++LL + GP+L + F A S +F
Sbjct: 1555 IFKELLQNADDASATECNFLIDMRKNNDIRENLLDPGMIACHGPSLWS-FNNAVFSDTDF 1613
Query: 521 SNFQLLPPWKLRGNTLN---YGLGLVGCYSICDLLSVVSGGYFYMFDPRGLVLS--APSS 575
N L R +GLG Y I D+ ++S + +FDP +S
Sbjct: 1614 LNITRLGGSVKRSEADKVGKFGLGFNSVYHITDIPIIMSREFMIIFDPNINHISKHIRDR 1673
Query: 576 NAPSGKMFSLIGTDLAQRFGDQFSPML--------IDQNDLWSLSDSTIIRMPLSSDCLK 627
+ P K+ ++F +QF P + + Q+ + + T+ R+P ++
Sbjct: 1674 SNPGIKINWSKQQKRLRKFPNQFKPFINVFGCQLPLAQDSPYKF-NGTLFRLPFRTEQEA 1732
Query: 628 VGHDVAS-----NRIKHITDVFMEHGSRTLLFLKSV 658
+++S I + D F G R +LF + V
Sbjct: 1733 SQSEISSLYYNTTDIYSLVDEFSICGHRFILFTQHV 1768
Score = 46.6 bits (109), Expect = 0.008
Identities = 40/154 (25%), Positives = 65/154 (41%), Gaps = 15/154 (9%)
Query: 257 EYINTDDFNDLKARLDGVSWVWIGDDFVSPNA----LAFDSPVKFTPYLYVVSSELSEYK 312
E++N D D + L GV++V + D + + + D+ F PYLY + EL +
Sbjct: 3856 EFLNGDK-RDFRYHLRGVAFVIVEDGWKLLKSEEVVINLDNESDFKPYLYKLPLELGTFH 3914
Query: 313 DLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQL--------NFVRCVHEAIAECC 364
L LG Y VL R+ + G L +++ F + +H E
Sbjct: 3915 QLFKLLGTEDVVSTKQYTEVLWRIYKNSEGKQLDPNEMRTVKRVVSGFFKSLHNDPVE-- 3972
Query: 365 LEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAP 398
+ K L D ++P G L + LV++DAP
Sbjct: 3973 IRKDLENLRDLTFYLPSHDGKLAKSSSLVFDDAP 4006
Score = 43.1 bits (100), Expect = 0.084
Identities = 43/148 (29%), Positives = 74/148 (49%), Gaps = 11/148 (7%)
Query: 1492 DSNGSSFLRALGVLELNDQQILVRFGLPGYERK--SMNEQEDILIYVFKNWHDLQS-NQS 1548
D ++ L + +L + L +F + ER + E I+++ ++ L++ N S
Sbjct: 1048 DEESIRLIKMLNIEQLTTTECL-KFIVHDIERGFYTTEEMAHIMLWALQHMAFLKNENPS 1106
Query: 1549 VVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERK-KFP-GERFSTDGWLR 1606
V+ L KF++ L+K +LFDP IL ++F+ E K +FP E S+ L
Sbjct: 1107 VLSWLSPIKFIQLP---CGRLVKASDLFDPELEILQNLFYMEEKSRFPTSELASSPDVLH 1163
Query: 1607 ILRKLGLRTATEVDV--IIECAKRVEFL 1632
LR+LGLR ++ ++ AKR+E L
Sbjct: 1164 SLRQLGLRNEVQLSERDVVTVAKRIEEL 1191
Score = 38.9 bits (89), Expect = 1.6
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 5/85 (5%)
Query: 730 IDRWLLALSLGSGQTRNMALDRRYLAYNLTPVAGIAALISRNGHHADVYSTSS-----IM 784
+ WL+ + + + +L L P G+A L+S +H T++ +
Sbjct: 1892 VTNWLICSCMDANEALKFSLSDSGKRLGLVPCGGVAVLLSEEENHKWTVKTNATPSGEVF 1951
Query: 785 TPLPLSGCINLPVTVLGCFLVCHNR 809
LPL LPV + GCF V NR
Sbjct: 1952 CYLPLRIKTGLPVHINGCFAVTSNR 1976
>gb|AAF31262.1| sacsin [Homo sapiens] gi|13124523|sp|Q9NZJ4|SACS_HUMAN Sacsin
Length = 3829
Score = 129 bits (325), Expect = 7e-28
Identities = 182/811 (22%), Positives = 330/811 (40%), Gaps = 94/811 (11%)
Query: 132 INDMVEEEFWSELKLITWCPVILDPAVRGLPWLKSS---KQVALPTVVRPKSQMWLVSSS 188
I D ++F ++ + I + P + PA L W +S + + T + +V
Sbjct: 1448 IRDPRAKDFAAKYQTIRFLPFLTKPAGFSLDWKGNSFKPETMFAATDLYTAEHQDIVCLL 1507
Query: 189 MLILDGE------CGTTYLQTK--LGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDF 240
IL+ CG+ L K LG + P + ++ QL E++KS +D
Sbjct: 1508 QPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKEVAKS---------VDDGI 1558
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKA--RLDGVSWVWIGDDFVSPNALAFDSPVKFT 298
+ + Y L E + ++ + +L S++ + + +V ++F +
Sbjct: 1559 TLYQENITNACYKYLHEALMQNEITKMSIIDKLKPFSFILVENAYVDSEKVSFHLNFEAA 1618
Query: 299 PYLYVVSSEL-SEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRC-- 355
PYLY + ++ + +++L +GVR S + D+ VL+ + + G T++ NF C
Sbjct: 1619 PYLYQLPNKYKNNFRELFETVGVRQSCTVEDFALVLESIDQE-RGTKQITEE-NFQLCRR 1676
Query: 356 -VHEAIAECCLEKP--LFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSLIGRHFVH 412
+ E I EK E + +PDT +L+ A L YND PW++ + + H
Sbjct: 1677 IISEGIWSLIREKKQEFCEKNYGKILLPDTNLMLLPAKSLCYNDCPWIKVKDTTVK-YCH 1735
Query: 413 PSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGY---------NKVSELLALYGNSEFL 463
I ++A +LG R +L +G +++ +L Y + + +
Sbjct: 1736 ADIPREVAVKLGAVPKRHKALERYASNVCFTTLGTEFGQKEKLTSRIKSILNAYPSEKEM 1795
Query: 464 LFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSNF 523
L +LL+ AD KA ++ ++D R+HP + QGPAL ++ + ++
Sbjct: 1796 LKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPAL-CVYNNQPFTEDDVRGI 1854
Query: 524 QLLPPWKLRGN---TLNYGLGLVGCYSICDLLSVVSGG-YFYMFDPRGLVLSAPSSNAPS 579
Q L GN T YG+G Y I D S +SG +FDP +S +P
Sbjct: 1855 QNLGKGTKEGNPYKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSISP- 1913
Query: 580 GKMFSLIGTDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPL-SSDCLKVGH----DVAS 634
G+MF + D +F D L + L + T+ R PL +++ KV +
Sbjct: 1914 GRMFRDLDADFRTQFSDVLDLYL---GTHFKLDNCTMFRFPLRNAEMAKVSEISSVPASD 1970
Query: 635 NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEE--GHSHPCQNFSISIDPSSSIMRNPF 692
++++ D G+ L+FL + ++SI ++ G + + I + R F
Sbjct: 1971 RMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKSTGALNVLYSVKGKITDGDRLKRKQF 2030
Query: 693 SEKKWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLALSLGSGQ----TRNMA 748
R + +D SEG + WL+ G ++++
Sbjct: 2031 HASVIDSVTKKRQLKDIPVQQITYTMDTE-DSEGN--LTTWLICNRSGFSSMEKVSKSVI 2087
Query: 749 LDRRYLAYNLTPVAGIAALISRN---GHHADVYSTSSIMTPLPLSGCINLPVTVLGCFLV 805
+ L P G+AA I+ N H A + LPLS LP V G F +
Sbjct: 2088 SAHKNQDITLFPRGGVAACITHNYKKPHRAFCF--------LPLSLETGLPFHVNGHFAL 2139
Query: 806 CHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNRELMSC-VCDSYVEMILEIQNL---RK 861
R R L++ D G + WN LM+ + +YVE++++++
Sbjct: 2140 DSAR-RNLWR-----------DDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGS 2187
Query: 862 DVSSSIIDSSACPGINLSLKAYGDNIYSFWP 892
D + S++ ++ + +LK + SF+P
Sbjct: 2188 DPTLSVLQNTPIHVVKDTLKKF----LSFFP 2214
Score = 50.8 bits (120), Expect = 4e-04
Identities = 105/468 (22%), Positives = 176/468 (37%), Gaps = 81/468 (17%)
Query: 144 LKLITWCPVILD--PAVRG-LPWLKSSKQVALPTVVRPKSQMWLVSSSMLILDGECGTTY 200
LK I W P + P G L W + P + L+ SS+ ++ E
Sbjct: 401 LKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDVGHAILIGSSLPLV--ESIHVN 458
Query: 201 LQTKLGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDFDVKLQKEIPCLYSKLQEYIN 260
L+ LG P++ + + ++ + KT S D D+ + Q + +Y + +++N
Sbjct: 459 LEKALGIFTKPSLSAVLKHF-KIVVDWYSSKTFS--DEDY-YQFQHILLEIYGFMHDHLN 514
Query: 261 T--DDFNDLKARLDGVSWVWIGDDFVSPNALAFDSPVK---FTPYLYVVSSELSEYKDLM 315
D F LK WVW G F P A A P+ PYL+ V ++++ L
Sbjct: 515 EGKDSFRALK-----FPWVWTGKKFC-PLAQAVIKPIHDLDLQPYLHNVPKTMAKFHQLF 568
Query: 316 ---------------------------------IKLGVRLSFGILDYLHVLQRLQNDLNG 342
K + L I+ +L+ Q +
Sbjct: 569 KVCGSIEELTSDHISMVIQKIYLKSDQDLSEQESKQNLHLMLNIIRWLYSNQIPASPNTP 628
Query: 343 VPLSTDQLNFVRCVHEAIAECCLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLEN 402
VP+ + N + + + I ECC + + L +L+H D+ A WL+
Sbjct: 629 VPIHHSK-NPSKLIMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHE-DIPMKTAEWLKV 686
Query: 403 SSLIGRHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGYNKVSELLALYGNSEF 462
L R ++P E +G + S E +T ++ +L Y +
Sbjct: 687 PCLSTR-LINP-------ENMGFEQ----SGQREPLTV--------RIKNILEEYPSVSD 726
Query: 463 LLFDLLELADCCKAKKLHLIYDKREHP--RQSLLQHNLGEFQGPALVAIFEGACLSREEF 520
+ +LL+ AD A + + D R + R++LL + GPAL + F + S +F
Sbjct: 727 IFKELLQNADDANATECSFLIDMRRNMDIRENLLDPGMAACHGPALWS-FNNSQFSDSDF 785
Query: 521 SNFQLLPPWKLRGNTLN---YGLGLVGCYSICDLLSVVSGGYFYMFDP 565
N L RG +GLG Y I D+ ++S + MFDP
Sbjct: 786 VNITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDP 833
Score = 48.9 bits (115), Expect = 0.002
Identities = 50/219 (22%), Positives = 94/219 (42%), Gaps = 42/219 (19%)
Query: 1442 AQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPSNSFFKPHDEHCLSYATDSNGSSFL-- 1499
+Q++I+IL+SLP YK++ G Y + C + + S P E + T S+ S+FL
Sbjct: 2650 SQDDIKILKSLPCYKSISGRYVSIGKFGTCYVLTKSI--PSAE--VEKWTQSSSSAFLEE 2705
Query: 1500 --------RALGVLELNDQQILVRFGLPGYERKSMNEQEDILIY---------------- 1535
+G + ++D ++ ++ LP E S + + + LIY
Sbjct: 2706 KIHLKELYEVIGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLSSAEELSEIKE 2765
Query: 1536 -VFKNWHDLQSNQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKKF 1594
+F+ L LK+ K + +++ P++LF P D FF + ++
Sbjct: 2766 QLFEKLESLLIIHDANSRLKQAKHFYDRTVRVFEVMLPEKLFIPND------FFKKLEQL 2819
Query: 1595 PGER----FSTDGWLRILRKLGLRTATEVDVIIECAKRV 1629
+ F T W+ LR +GL+ +++ AK +
Sbjct: 2820 IKPKNHVTFMT-SWVEFLRNIGLKYILSQQQLLQFAKEI 2857
Score = 44.3 bits (103), Expect = 0.038
Identities = 38/168 (22%), Positives = 74/168 (43%), Gaps = 11/168 (6%)
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDF--VSPNALAFDSPVK-- 296
D ++ K + + E+++ + + + +L GV++V + D + + P + + +
Sbjct: 3012 DEEMVKTRAKVLRSIYEFLSAEK-REFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYESD 3070
Query: 297 FTPYLYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCV 356
F PYLY + EL + L LG Y+ VL R+ + G L +++ V+ V
Sbjct: 3071 FKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRV 3130
Query: 357 HEAIAECC------LEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAP 398
+ + L D L++P G L+ + LV++DAP
Sbjct: 3131 VSGLFRSLQNDSVKVRSDLENVRDLALYLPSQDGRLVKSSILVFDDAP 3178
>emb|CAI13923.1| spastic ataxia of Charlevoix-Saguenay (sacsin) [Homo sapiens]
Length = 4579
Score = 129 bits (325), Expect = 7e-28
Identities = 182/811 (22%), Positives = 330/811 (40%), Gaps = 94/811 (11%)
Query: 132 INDMVEEEFWSELKLITWCPVILDPAVRGLPWLKSS---KQVALPTVVRPKSQMWLVSSS 188
I D ++F ++ + I + P + PA L W +S + + T + +V
Sbjct: 2198 IRDPRAKDFAAKYQTIRFLPFLTKPAGFSLDWKGNSFKPETMFAATDLYTAEHQDIVCLL 2257
Query: 189 MLILDGE------CGTTYLQTK--LGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDF 240
IL+ CG+ L K LG + P + ++ QL E++KS +D
Sbjct: 2258 QPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKEVAKS---------VDDGI 2308
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKA--RLDGVSWVWIGDDFVSPNALAFDSPVKFT 298
+ + Y L E + ++ + +L S++ + + +V ++F +
Sbjct: 2309 TLYQENITNACYKYLHEALMQNEITKMSIIDKLKPFSFILVENAYVDSEKVSFHLNFEAA 2368
Query: 299 PYLYVVSSEL-SEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRC-- 355
PYLY + ++ + +++L +GVR S + D+ VL+ + + G T++ NF C
Sbjct: 2369 PYLYQLPNKYKNNFRELFETVGVRQSCTVEDFALVLESIDQE-RGTKQITEE-NFQLCRR 2426
Query: 356 -VHEAIAECCLEKP--LFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSLIGRHFVH 412
+ E I EK E + +PDT +L+ A L YND PW++ + + H
Sbjct: 2427 IISEGIWSLIREKKQEFCEKNYGKILLPDTNLMLLPAKSLCYNDCPWIKVKDTTVK-YCH 2485
Query: 413 PSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGY---------NKVSELLALYGNSEFL 463
I ++A +LG R +L +G +++ +L Y + + +
Sbjct: 2486 ADIPREVAVKLGAVPKRHKALERYASNVCFTTLGTEFGQKEKLTSRIKSILNAYPSEKEM 2545
Query: 464 LFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSNF 523
L +LL+ AD KA ++ ++D R+HP + QGPAL ++ + ++
Sbjct: 2546 LKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPAL-CVYNNQPFTEDDVRGI 2604
Query: 524 QLLPPWKLRGN---TLNYGLGLVGCYSICDLLSVVSGG-YFYMFDPRGLVLSAPSSNAPS 579
Q L GN T YG+G Y I D S +SG +FDP +S +P
Sbjct: 2605 QNLGKGTKEGNPYKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSISP- 2663
Query: 580 GKMFSLIGTDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPL-SSDCLKVGH----DVAS 634
G+MF + D +F D L + L + T+ R PL +++ KV +
Sbjct: 2664 GRMFRDLDADFRTQFSDVLDLYL---GTHFKLDNCTMFRFPLRNAEMAKVSEISSVPASD 2720
Query: 635 NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEE--GHSHPCQNFSISIDPSSSIMRNPF 692
++++ D G+ L+FL + ++SI ++ G + + I + R F
Sbjct: 2721 RMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKSTGALNVLYSVKGKITDGDRLKRKQF 2780
Query: 693 SEKKWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLALSLGSGQ----TRNMA 748
R + +D SEG + WL+ G ++++
Sbjct: 2781 HASVIDSVTKKRQLKDIPVQQITYTMDTE-DSEGN--LTTWLICNRSGFSSMEKVSKSVI 2837
Query: 749 LDRRYLAYNLTPVAGIAALISRN---GHHADVYSTSSIMTPLPLSGCINLPVTVLGCFLV 805
+ L P G+AA I+ N H A + LPLS LP V G F +
Sbjct: 2838 SAHKNQDITLFPRGGVAACITHNYKKPHRAFCF--------LPLSLETGLPFHVNGHFAL 2889
Query: 806 CHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNRELMSC-VCDSYVEMILEIQNL---RK 861
R R L++ D G + WN LM+ + +YVE++++++
Sbjct: 2890 DSAR-RNLWR-----------DDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGS 2937
Query: 862 DVSSSIIDSSACPGINLSLKAYGDNIYSFWP 892
D + S++ ++ + +LK + SF+P
Sbjct: 2938 DPTLSVLQNTPIHVVKDTLKKF----LSFFP 2964
Score = 79.3 bits (194), Expect = 1e-12
Identities = 135/619 (21%), Positives = 244/619 (38%), Gaps = 89/619 (14%)
Query: 450 VSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAI 509
+ ++L Y +L +L++ A+ A ++ +YD+ ++ ++L ++ +QGPAL +
Sbjct: 100 LKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAPYQGPALY-V 158
Query: 510 FEGACLSREEFSNFQLLPPWKLRGNTL---NYGLGLVGCYSICDLLSVVSGGYFYMFDPR 566
+ A + E++ Q + + + + L +G+G Y I D+ + SG M DP
Sbjct: 159 YNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPH 218
Query: 567 GLVLSAPSSNAPSGKMFSL-IGTDLAQRFGDQFSPML-----IDQNDLWSLSDSTIIRMP 620
+ SG+ ++L + DQF+P + + + T R P
Sbjct: 219 QTLFGPHE----SGQCWNLKDDSKEISELSDQFAPFVGIFGSTKETFINGNFPGTFFRFP 274
Query: 621 LSSDCLKVGHDVAS-NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEEGHSHPCQNFSI 679
L ++ ++ + ++ + + F LLFLKSV VS+ E + F +
Sbjct: 275 LRLQPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQDVSLYVREADGTEKLV-FRV 333
Query: 680 SIDPSSSIMRNPFSEKKWRKFQLS---RLFSSSNTAIKMHVIDVSLYSEGTTFIDR--WL 734
+ S ++ + K +S + S+N + +++ L E T + WL
Sbjct: 334 TSSESKALKHERPNSIKILGTAISNYCKKTPSNNITCVTYHVNIVLEEESTKDAQKTSWL 393
Query: 735 LALSLGSGQTRNMALDRRYLAYNLTPVAGIAALIS-----RNGHHADVYSTSSIMTPLP- 788
+ S+G G+ + LD P+ GIA +S G +D + PLP
Sbjct: 394 VCNSVG-GRGISSKLDSLADELKFVPIIGIAMPLSSRDDEAKGATSDFSGKAFCFLPLPP 452
Query: 789 -LSGCINLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNREL-MSCVC 846
LPV + G F + N RR+ D LWN L M+ V
Sbjct: 453 GEESSTGLPVHISGFFGLTDN----------RRSIKWRELDQWRDPAALWNEFLVMNVVP 502
Query: 847 DSYVEMILE-IQNLRKDVSSSIIDSSACPGINLSLKAYGDNIYSFWPRSSEGHVPSGQLF 905
+Y +IL+ I+ L + SS LS+ D IY WP +S+
Sbjct: 503 KAYATLILDSIKRLEMEKSSD---------FPLSV----DVIYKLWPEASK--------- 540
Query: 906 DHNNTPSSSTAVLKADWECLKERVIHPFYSRIVDLPVWQLYSGNLVKAGEGMFLSQPGNG 965
+K W + V+ P +S ++ V S + V+ + F N
Sbjct: 541 ------------VKVHW----QPVLEPLFSELLQNAVIYSISCDWVRLEQVYFSELDENL 584
Query: 966 MIGSLLPGTVCSFVKEHYPVFSVPWELVTEIQVVGFS----VREVRPKMVRDLLKVSSKP 1021
+ + S K+ + VP + +Q+ S VR+V P VR +L+ K
Sbjct: 585 EYTKTVLNYLQSSGKQ---IAKVPGNVDAAVQLTAASGTTPVRKVTPAWVRQVLR---KC 638
Query: 1022 IVLRSVDMYIDVLEYCLSN 1040
L + + +LE+ LS+
Sbjct: 639 AHLGCAEEKLHLLEFVLSD 657
Score = 50.8 bits (120), Expect = 4e-04
Identities = 105/468 (22%), Positives = 176/468 (37%), Gaps = 81/468 (17%)
Query: 144 LKLITWCPVILD--PAVRG-LPWLKSSKQVALPTVVRPKSQMWLVSSSMLILDGECGTTY 200
LK I W P + P G L W + P + L+ SS+ ++ E
Sbjct: 1151 LKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDVGHAILIGSSLPLV--ESIHVN 1208
Query: 201 LQTKLGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDFDVKLQKEIPCLYSKLQEYIN 260
L+ LG P++ + + ++ + KT S D D+ + Q + +Y + +++N
Sbjct: 1209 LEKALGIFTKPSLSAVLKHF-KIVVDWYSSKTFS--DEDY-YQFQHILLEIYGFMHDHLN 1264
Query: 261 T--DDFNDLKARLDGVSWVWIGDDFVSPNALAFDSPVK---FTPYLYVVSSELSEYKDLM 315
D F LK WVW G F P A A P+ PYL+ V ++++ L
Sbjct: 1265 EGKDSFRALK-----FPWVWTGKKFC-PLAQAVIKPIHDLDLQPYLHNVPKTMAKFHQLF 1318
Query: 316 ---------------------------------IKLGVRLSFGILDYLHVLQRLQNDLNG 342
K + L I+ +L+ Q +
Sbjct: 1319 KVCGSIEELTSDHISMVIQKIYLKSDQDLSEQESKQNLHLMLNIIRWLYSNQIPASPNTP 1378
Query: 343 VPLSTDQLNFVRCVHEAIAECCLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLEN 402
VP+ + N + + + I ECC + + L +L+H D+ A WL+
Sbjct: 1379 VPIHHSK-NPSKLIMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHE-DIPMKTAEWLKV 1436
Query: 403 SSLIGRHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGYNKVSELLALYGNSEF 462
L R ++P E +G + S E +T ++ +L Y +
Sbjct: 1437 PCLSTR-LINP-------ENMGFEQ----SGQREPLTV--------RIKNILEEYPSVSD 1476
Query: 463 LLFDLLELADCCKAKKLHLIYDKREHP--RQSLLQHNLGEFQGPALVAIFEGACLSREEF 520
+ +LL+ AD A + + D R + R++LL + GPAL + F + S +F
Sbjct: 1477 IFKELLQNADDANATECSFLIDMRRNMDIRENLLDPGMAACHGPALWS-FNNSQFSDSDF 1535
Query: 521 SNFQLLPPWKLRGNTLN---YGLGLVGCYSICDLLSVVSGGYFYMFDP 565
N L RG +GLG Y I D+ ++S + MFDP
Sbjct: 1536 VNITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDP 1583
Score = 48.9 bits (115), Expect = 0.002
Identities = 50/219 (22%), Positives = 94/219 (42%), Gaps = 42/219 (19%)
Query: 1442 AQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPSNSFFKPHDEHCLSYATDSNGSSFL-- 1499
+Q++I+IL+SLP YK++ G Y + C + + S P E + T S+ S+FL
Sbjct: 3400 SQDDIKILKSLPCYKSISGRYVSIGKFGTCYVLTKSI--PSAE--VEKWTQSSSSAFLEE 3455
Query: 1500 --------RALGVLELNDQQILVRFGLPGYERKSMNEQEDILIY---------------- 1535
+G + ++D ++ ++ LP E S + + + LIY
Sbjct: 3456 KIHLKELYEVIGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLSSAEELSEIKE 3515
Query: 1536 -VFKNWHDLQSNQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKKF 1594
+F+ L LK+ K + +++ P++LF P D FF + ++
Sbjct: 3516 QLFEKLESLLIIHDANSRLKQAKHFYDRTVRVFEVMLPEKLFIPND------FFKKLEQL 3569
Query: 1595 PGER----FSTDGWLRILRKLGLRTATEVDVIIECAKRV 1629
+ F T W+ LR +GL+ +++ AK +
Sbjct: 3570 IKPKNHVTFMT-SWVEFLRNIGLKYILSQQQLLQFAKEI 3607
Score = 44.3 bits (103), Expect = 0.038
Identities = 38/168 (22%), Positives = 74/168 (43%), Gaps = 11/168 (6%)
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDF--VSPNALAFDSPVK-- 296
D ++ K + + E+++ + + + +L GV++V + D + + P + + +
Sbjct: 3762 DEEMVKTRAKVLRSIYEFLSAEK-REFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYESD 3820
Query: 297 FTPYLYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCV 356
F PYLY + EL + L LG Y+ VL R+ + G L +++ V+ V
Sbjct: 3821 FKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRV 3880
Query: 357 HEAIAECC------LEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAP 398
+ + L D L++P G L+ + LV++DAP
Sbjct: 3881 VSGLFRSLQNDSVKVRSDLENVRDLALYLPSQDGRLVKSSILVFDDAP 3928
>ref|NP_055178.2| sacsin [Homo sapiens]
Length = 4432
Score = 129 bits (325), Expect = 7e-28
Identities = 182/811 (22%), Positives = 330/811 (40%), Gaps = 94/811 (11%)
Query: 132 INDMVEEEFWSELKLITWCPVILDPAVRGLPWLKSS---KQVALPTVVRPKSQMWLVSSS 188
I D ++F ++ + I + P + PA L W +S + + T + +V
Sbjct: 2051 IRDPRAKDFAAKYQTIRFLPFLTKPAGFSLDWKGNSFKPETMFAATDLYTAEHQDIVCLL 2110
Query: 189 MLILDGE------CGTTYLQTK--LGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDF 240
IL+ CG+ L K LG + P + ++ QL E++KS +D
Sbjct: 2111 QPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKEVAKS---------VDDGI 2161
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKA--RLDGVSWVWIGDDFVSPNALAFDSPVKFT 298
+ + Y L E + ++ + +L S++ + + +V ++F +
Sbjct: 2162 TLYQENITNACYKYLHEALMQNEITKMSIIDKLKPFSFILVENAYVDSEKVSFHLNFEAA 2221
Query: 299 PYLYVVSSEL-SEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRC-- 355
PYLY + ++ + +++L +GVR S + D+ VL+ + + G T++ NF C
Sbjct: 2222 PYLYQLPNKYKNNFRELFETVGVRQSCTVEDFALVLESIDQE-RGTKQITEE-NFQLCRR 2279
Query: 356 -VHEAIAECCLEKP--LFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSLIGRHFVH 412
+ E I EK E + +PDT +L+ A L YND PW++ + + H
Sbjct: 2280 IISEGIWSLIREKKQEFCEKNYGKILLPDTNLMLLPAKSLCYNDCPWIKVKDTTVK-YCH 2338
Query: 413 PSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGY---------NKVSELLALYGNSEFL 463
I ++A +LG R +L +G +++ +L Y + + +
Sbjct: 2339 ADIPREVAVKLGAVPKRHKALERYASNVCFTTLGTEFGQKEKLTSRIKSILNAYPSEKEM 2398
Query: 464 LFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSNF 523
L +LL+ AD KA ++ ++D R+HP + QGPAL ++ + ++
Sbjct: 2399 LKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPAL-CVYNNQPFTEDDVRGI 2457
Query: 524 QLLPPWKLRGN---TLNYGLGLVGCYSICDLLSVVSGG-YFYMFDPRGLVLSAPSSNAPS 579
Q L GN T YG+G Y I D S +SG +FDP +S +P
Sbjct: 2458 QNLGKGTKEGNPYKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSISP- 2516
Query: 580 GKMFSLIGTDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPL-SSDCLKVGH----DVAS 634
G+MF + D +F D L + L + T+ R PL +++ KV +
Sbjct: 2517 GRMFRDLDADFRTQFSDVLDLYL---GTHFKLDNCTMFRFPLRNAEMAKVSEISSVPASD 2573
Query: 635 NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEE--GHSHPCQNFSISIDPSSSIMRNPF 692
++++ D G+ L+FL + ++SI ++ G + + I + R F
Sbjct: 2574 RMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKSTGALNVLYSVKGKITDGDRLKRKQF 2633
Query: 693 SEKKWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLALSLGSGQ----TRNMA 748
R + +D SEG + WL+ G ++++
Sbjct: 2634 HASVIDSVTKKRQLKDIPVQQITYTMDTE-DSEGN--LTTWLICNRSGFSSMEKVSKSVI 2690
Query: 749 LDRRYLAYNLTPVAGIAALISRN---GHHADVYSTSSIMTPLPLSGCINLPVTVLGCFLV 805
+ L P G+AA I+ N H A + LPLS LP V G F +
Sbjct: 2691 SAHKNQDITLFPRGGVAACITHNYKKPHRAFCF--------LPLSLETGLPFHVNGHFAL 2742
Query: 806 CHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNRELMSC-VCDSYVEMILEIQNL---RK 861
R R L++ D G + WN LM+ + +YVE++++++
Sbjct: 2743 DSAR-RNLWR-----------DDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGS 2790
Query: 862 DVSSSIIDSSACPGINLSLKAYGDNIYSFWP 892
D + S++ ++ + +LK + SF+P
Sbjct: 2791 DPTLSVLQNTPIHVVKDTLKKF----LSFFP 2817
Score = 63.2 bits (152), Expect = 8e-08
Identities = 126/571 (22%), Positives = 218/571 (38%), Gaps = 89/571 (15%)
Query: 498 LGEFQGPALVAIFEGACLSREEFSNFQLLPPWKLRGNTLN---YGLGLVGCYSICDLLSV 554
+ +QGPAL ++ A + E++ Q + + + + L +G+G Y I D+ +
Sbjct: 1 MAPYQGPALY-VYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCI 59
Query: 555 VSGGYFYMFDPRGLVLSAPSSNAPSGKMFSL-IGTDLAQRFGDQFSPML-----IDQNDL 608
SG M DP + SG+ ++L + DQF+P + + +
Sbjct: 60 FSGDQIGMLDPHQTLFGPHE----SGQCWNLKDDSKEISELSDQFAPFVGIFGSTKETFI 115
Query: 609 WSLSDSTIIRMPLSSDCLKVGHDVAS-NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWE 667
T R PL ++ ++ + ++ + + F LLFLKSV VS+ E
Sbjct: 116 NGNFPGTFFRFPLRLQPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQDVSLYVRE 175
Query: 668 EGHSHPCQNFSISIDPSSSIMRNPFSEKKWRKFQLS---RLFSSSNTAIKMHVIDVSLYS 724
+ F ++ S ++ + K +S + S+N + +++ L
Sbjct: 176 ADGTEKLV-FRVTSSESKALKHERPNSIKILGTAISNYCKKTPSNNITCVTYHVNIVLEE 234
Query: 725 EGTTFIDR--WLLALSLGSGQTRNMALDRRYLAYNLTPVAGIAALIS-----RNGHHADV 777
E T + WL+ S+G G+ + LD P+ GIA +S G +D
Sbjct: 235 ESTKDAQKTSWLVCNSVG-GRGISSKLDSLADELKFVPIIGIAMPLSSRDDEAKGATSDF 293
Query: 778 YSTSSIMTPLP--LSGCINLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIE 835
+ PLP LPV + G F + N RR+ D
Sbjct: 294 SGKAFCFLPLPPGEESSTGLPVHISGFFGLTDN----------RRSIKWRELDQWRDPAA 343
Query: 836 LWNREL-MSCVCDSYVEMILE-IQNLRKDVSSSIIDSSACPGINLSLKAYGDNIYSFWPR 893
LWN L M+ V +Y +IL+ I+ L + SS LS+ D IY WP
Sbjct: 344 LWNEFLVMNVVPKAYATLILDSIKRLEMEKSSD---------FPLSV----DVIYKLWPE 390
Query: 894 SSEGHVPSGQLFDHNNTPSSSTAVLKADWECLKERVIHPFYSRIVDLPVWQLYSGNLVKA 953
+S+ +K W + V+ P +S ++ V S + V+
Sbjct: 391 ASK---------------------VKVHW----QPVLEPLFSELLQNAVIYSISCDWVRL 425
Query: 954 GEGMFLSQPGNGMIGSLLPGTVCSFVKEHYPVFSVPWELVTEIQVVGFS----VREVRPK 1009
+ F N + + S K+ + VP + +Q+ S VR+V P
Sbjct: 426 EQVYFSELDENLEYTKTVLNYLQSSGKQ---IAKVPGNVDAAVQLTAASGTTPVRKVTPA 482
Query: 1010 MVRDLLKVSSKPIVLRSVDMYIDVLEYCLSN 1040
VR +L+ K L + + +LE+ LS+
Sbjct: 483 WVRQVLR---KCAHLGCAEEKLHLLEFVLSD 510
Score = 50.8 bits (120), Expect = 4e-04
Identities = 105/468 (22%), Positives = 176/468 (37%), Gaps = 81/468 (17%)
Query: 144 LKLITWCPVILD--PAVRG-LPWLKSSKQVALPTVVRPKSQMWLVSSSMLILDGECGTTY 200
LK I W P + P G L W + P + L+ SS+ ++ E
Sbjct: 1004 LKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDVGHAILIGSSLPLV--ESIHVN 1061
Query: 201 LQTKLGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDFDVKLQKEIPCLYSKLQEYIN 260
L+ LG P++ + + ++ + KT S D D+ + Q + +Y + +++N
Sbjct: 1062 LEKALGIFTKPSLSAVLKHF-KIVVDWYSSKTFS--DEDY-YQFQHILLEIYGFMHDHLN 1117
Query: 261 T--DDFNDLKARLDGVSWVWIGDDFVSPNALAFDSPVK---FTPYLYVVSSELSEYKDLM 315
D F LK WVW G F P A A P+ PYL+ V ++++ L
Sbjct: 1118 EGKDSFRALK-----FPWVWTGKKFC-PLAQAVIKPIHDLDLQPYLHNVPKTMAKFHQLF 1171
Query: 316 ---------------------------------IKLGVRLSFGILDYLHVLQRLQNDLNG 342
K + L I+ +L+ Q +
Sbjct: 1172 KVCGSIEELTSDHISMVIQKIYLKSDQDLSEQESKQNLHLMLNIIRWLYSNQIPASPNTP 1231
Query: 343 VPLSTDQLNFVRCVHEAIAECCLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLEN 402
VP+ + N + + + I ECC + + L +L+H D+ A WL+
Sbjct: 1232 VPIHHSK-NPSKLIMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHE-DIPMKTAEWLKV 1289
Query: 403 SSLIGRHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGYNKVSELLALYGNSEF 462
L R ++P E +G + S E +T ++ +L Y +
Sbjct: 1290 PCLSTR-LINP-------ENMGFEQ----SGQREPLTV--------RIKNILEEYPSVSD 1329
Query: 463 LLFDLLELADCCKAKKLHLIYDKREHP--RQSLLQHNLGEFQGPALVAIFEGACLSREEF 520
+ +LL+ AD A + + D R + R++LL + GPAL + F + S +F
Sbjct: 1330 IFKELLQNADDANATECSFLIDMRRNMDIRENLLDPGMAACHGPALWS-FNNSQFSDSDF 1388
Query: 521 SNFQLLPPWKLRGNTLN---YGLGLVGCYSICDLLSVVSGGYFYMFDP 565
N L RG +GLG Y I D+ ++S + MFDP
Sbjct: 1389 VNITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDP 1436
Score = 48.9 bits (115), Expect = 0.002
Identities = 50/219 (22%), Positives = 94/219 (42%), Gaps = 42/219 (19%)
Query: 1442 AQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPSNSFFKPHDEHCLSYATDSNGSSFL-- 1499
+Q++I+IL+SLP YK++ G Y + C + + S P E + T S+ S+FL
Sbjct: 3253 SQDDIKILKSLPCYKSISGRYVSIGKFGTCYVLTKSI--PSAE--VEKWTQSSSSAFLEE 3308
Query: 1500 --------RALGVLELNDQQILVRFGLPGYERKSMNEQEDILIY---------------- 1535
+G + ++D ++ ++ LP E S + + + LIY
Sbjct: 3309 KIHLKELYEVIGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLSSAEELSEIKE 3368
Query: 1536 -VFKNWHDLQSNQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKKF 1594
+F+ L LK+ K + +++ P++LF P D FF + ++
Sbjct: 3369 QLFEKLESLLIIHDANSRLKQAKHFYDRTVRVFEVMLPEKLFIPND------FFKKLEQL 3422
Query: 1595 PGER----FSTDGWLRILRKLGLRTATEVDVIIECAKRV 1629
+ F T W+ LR +GL+ +++ AK +
Sbjct: 3423 IKPKNHVTFMT-SWVEFLRNIGLKYILSQQQLLQFAKEI 3460
Score = 44.3 bits (103), Expect = 0.038
Identities = 38/168 (22%), Positives = 74/168 (43%), Gaps = 11/168 (6%)
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDF--VSPNALAFDSPVK-- 296
D ++ K + + E+++ + + + +L GV++V + D + + P + + +
Sbjct: 3615 DEEMVKTRAKVLRSIYEFLSAEK-REFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYESD 3673
Query: 297 FTPYLYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCV 356
F PYLY + EL + L LG Y+ VL R+ + G L +++ V+ V
Sbjct: 3674 FKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRV 3733
Query: 357 HEAIAECC------LEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAP 398
+ + L D L++P G L+ + LV++DAP
Sbjct: 3734 VSGLFRSLQNDSVKVRSDLENVRDLALYLPSQDGRLVKSSILVFDDAP 3781
>ref|XP_224256.3| PREDICTED: similar to sacsin [Rattus norvegicus]
Length = 4801
Score = 128 bits (322), Expect = 2e-27
Identities = 180/811 (22%), Positives = 333/811 (40%), Gaps = 94/811 (11%)
Query: 132 INDMVEEEFWSELKLITWCPVILDPAVRGLPWLKSS---KQVALPTVVRPKSQMWLVSSS 188
I D ++F ++ + I + P + PA L W +S + + T + +V
Sbjct: 2419 IRDPRAKDFAAKYQTIPFLPFLTKPAGFSLEWKGNSFKPETMFAATDLYTAEYQDIVCLL 2478
Query: 189 MLILDGE------CGTTYLQTK--LGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDF 240
IL+ CG+ L K LG + P + ++ QL +++KS +D
Sbjct: 2479 QPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKQVAKS---------VDDGI 2529
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFND--LKARLDGVSWVWIGDDFVSPNALAFDSPVKFT 298
+ + Y L E I ++ + +L ++ + + +V ++F +
Sbjct: 2530 TLYQENITNACYKYLHEAILQNEMAKATIIEKLKPFCFILVENVYVESEKVSFHLNFEAA 2589
Query: 299 PYLYVVSSEL-SEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVR-CV 356
PYLY + ++ + +++L +GVR SF + D+ VL+ + + ++ + R +
Sbjct: 2590 PYLYQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQERGKKQITEENFQLCRRII 2649
Query: 357 HEAIAECCLEK--PLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLE--NSSLIGRHFVH 412
E I EK E + +PDT +L+ A L YND PW++ +SS+ + H
Sbjct: 2650 SEGIWSLIREKRQEFCEKNYGKILLPDTNLLLLPAKSLCYNDCPWIKVKDSSV---KYCH 2706
Query: 413 PSISNDLAERLGVQSVR--CLSLVSEDMTKDLPCMGY-------NKVSELLALYGNSEFL 463
I ++A +LG R L + ++ P + +++ +L Y + + +
Sbjct: 2707 ADIPREVAVKLGAIPKRHKALERYASNICFTAPGTEFGQKEKLTSRIKSILNAYPSEKEM 2766
Query: 464 LFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSNF 523
L +LL+ AD KA ++ ++D R+HP + QGPAL ++ + ++
Sbjct: 2767 LKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPAL-CVYNNQPFTEDDVRGI 2825
Query: 524 QLLPPWKLRGN---TLNYGLGLVGCYSICDLLSVVSGG-YFYMFDPRGLVLSAPSSNAPS 579
Q L GN T YG+G Y I D S +SG +FDP +S +P
Sbjct: 2826 QNLGKGTKEGNPCKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSVSP- 2884
Query: 580 GKMFSLIGTDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPLSSDCLKVGHDVAS----- 634
G+MF + D +F D L + + L + T+ R PL + + +++S
Sbjct: 2885 GRMFRDLDADFRTQFSDVLDLYL---GNHFKLDNCTMFRFPLRNAEMAQVSEISSVPSSD 2941
Query: 635 NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEE--GHSHPCQNFSISIDPSSSIMRNPF 692
++++ D G+ L+FL + ++SI ++ G + + I + R F
Sbjct: 2942 RMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATGGLNVLYSVKGKITDGDRLKRKQF 3001
Query: 693 SEKKWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLALSLGSGQ----TRNMA 748
R + +D SEG + WL+ G ++++
Sbjct: 3002 HASVIDSVTKKRQLKDIPVQQITYTMDTE-DSEGN--LTTWLICNRSGFSSMDKVSKSVI 3058
Query: 749 LDRRYLAYNLTPVAGIAALISRN---GHHADVYSTSSIMTPLPLSGCINLPVTVLGCFLV 805
R L P G+AA I+ N H A + LPLS LP V G F +
Sbjct: 3059 SAHRNQDITLFPRGGVAACITHNYKKPHRAFCF--------LPLSLETGLPFHVNGHFAL 3110
Query: 806 CHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNRELMSC-VCDSYVEMILEIQNL---RK 861
R R L++ D G + WN LM+ + +YVE++++++
Sbjct: 3111 DSAR-RNLWR-----------DDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGS 3158
Query: 862 DVSSSIIDSSACPGINLSLKAYGDNIYSFWP 892
D + S++ ++ + +LK + SF+P
Sbjct: 3159 DPTLSVLQNTPIHVVKDTLKKF----LSFFP 3185
Score = 88.6 bits (218), Expect = 2e-15
Identities = 159/691 (23%), Positives = 281/691 (40%), Gaps = 118/691 (17%)
Query: 400 LENSSLIGRHFVHPSISNDLAERLGVQSVR---CLSLVSE-----DMTKDL-------PC 444
L++ L G F+HP + L + GV+ R ++LVS +T + P
Sbjct: 151 LQSKGLKGGVFLHPPLHIFLLKTAGVEQCRQDLVINLVSHWASAPSVTSESRFGQTTPPL 210
Query: 445 MGYNKVSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGP 504
+ + K ++L Y +L +L++ A+ A ++ +YD+ ++ ++L ++ ++QG
Sbjct: 211 VDFLK--DILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAQYQGS 268
Query: 505 ALVAIFEGACLSREEFSNFQLLPPWKLRGNTL---NYGLGLVGCYSICDLLSVVSGGYFY 561
AL ++ A + E++ Q + + + + L +G+G Y I D+ + SG
Sbjct: 269 ALY-VYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIG 327
Query: 562 MFDPRGLVLSAPSSNAPSGKMFSLIGTDLAQ--RFGDQFSPML-----IDQNDLWSLSDS 614
M DP + SG+ ++L D+ + DQF+P + +
Sbjct: 328 MLDPHQTLFGPHE----SGQCWNL-KDDIKEINELPDQFAPFIGVFGSTKETFTNGSFPG 382
Query: 615 TIIRMPLSSDCLKVGHDV-ASNRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEEGHSHP 673
T R PL ++ ++ ++ + D F LLFLKSV VS+ E +
Sbjct: 383 TFFRFPLRLQPSQLSSNLYTKQKVLELFDSFRADADTVLLFLKSVQAVSLHVREADGTEK 442
Query: 674 CQNFSISIDPSSSIMRNPFSEKKWRKFQLS----RLFSSSNTAIKMHVIDVSLYSEGTTF 729
F ++ + ++ + K +S ++ S+S T + H I+++L E T
Sbjct: 443 LV-FRVTASENKTLKHERPNSIKILGTAISNYCKKIPSNSVTCVTYH-INIALEDESTKD 500
Query: 730 IDR--WLLALSLGSGQTRNMALDRRYLAYNLTPVAGIAALIS----RNGHHADVYSTSSI 783
+ WL+ S+G G+ + LD P+ G+A +S NG +D +
Sbjct: 501 AQKTSWLVCNSVG-GRGISSKLDSLADELKFVPIIGLAMSLSGRDEENGATSDFSGKAFC 559
Query: 784 MTPLP--LSGCINLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNREL 841
PLP LPV + G F + N RR+ D LWN+ L
Sbjct: 560 FLPLPPGEESRTGLPVHISGFFGLTDN----------RRSIKWRELDQWRDPAALWNQFL 609
Query: 842 -MSCVCDSYVEMILE-IQNLRKDVSSSIIDSSACPGINLSLKAYGDNIYSFWPRSSEGHV 899
++ V +Y +IL+ I+ L + SS LS+ D IY WP +S+
Sbjct: 610 IVNVVPKAYATLILDSIKRLETEKSSD---------FPLSV----DAIYKLWPEASK--- 653
Query: 900 PSGQLFDHNNTPSSSTAVLKADWECLKERVIHPFYSRIVDLPVWQLYSGNLVKAGEGMFL 959
+KA W V+ P +S + V +YS GE + L
Sbjct: 654 ------------------VKAHW----HPVLGPLFSELFQHAV--IYS----VGGEWVKL 685
Query: 960 SQPGNGMIGSLLPGT--VCSFV-KEHYPVFSVPWELVTEIQVVGFS-------VREVRPK 1009
Q + L T V +++ + + VP L +Q+ S VR+V P
Sbjct: 686 EQVHFSELDESLESTQSVLNYLQRSGKQIARVPGNLAAAVQLSAASATSTASPVRKVTPV 745
Query: 1010 MVRDLLKVSSKPIVLRSVDMYIDVLEYCLSN 1040
VR +L+ K L S + + +LE+ LS+
Sbjct: 746 WVRQVLR---KCAHLGSAEEKLHLLEFVLSD 773
Score = 68.9 bits (167), Expect = 1e-09
Identities = 94/411 (22%), Positives = 174/411 (41%), Gaps = 74/411 (18%)
Query: 1253 PSSDSQGGPSSEWIKIFWKS-FRGSQEELSLFSDWPLIPAF-LGRPVLC----RVRERHL 1306
P S+ + PS W+K+ WK+ + E+L+LF + PLIP L C R+R +
Sbjct: 987 PLSEDKHHPSISWLKMVWKNLYIHFSEDLTLFDEMPLIPRTPLDADQTCVELIRLRVPSV 1046
Query: 1307 VFIPPPLVQRTLQSGILDRESTENHVGGVSVSRDDTSVAEAYTSAFDRLKISYPWLLSLL 1366
V + + L + D +GG+ + R DTS+ + + S L
Sbjct: 1047 VILDDE-TEAQLPEFLAD---IVQKLGGIVLKRLDTSLQHPLVKKY---------IHSPL 1093
Query: 1367 NQCNVPIFDEAFIDCATSSNCFSMPGGSLGQVIASKLVAAKQAGYFTEPNNLSASSCDAL 1426
+ I ++ +P L IAS L K A AS D
Sbjct: 1094 PSAILQIMEK-------------IPLQKLCNQIASLLPTHKDA-----LRKFLASLTDT- 1134
Query: 1427 FSLFCDELFSNGFHYAQEEIEILRSLPIYKTV-------VGSYTKLKDQDQCMIPSNSFF 1479
+++E I++ L I+K + + SYTKLK C + ++
Sbjct: 1135 ---------------SEKEKRIIQELTIFKRINHSSDQGISSYTKLKG---CKVLDHTAK 1176
Query: 1480 KPHDEHCLSYATDSNGSSFLRALGVLELNDQQIL--VRFGLPGYERKSMNEQE--DILIY 1535
P + DS+ + +R +L++ + ++F L E ++E ++++
Sbjct: 1177 LPTELRLSVSVIDSSDEATIRLANMLKIEKLKTTSCLKFVLKDIENAFYTQEEVTRLMLW 1236
Query: 1536 VFKNWHDLQS-NQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKK- 1593
+ +N L++ N SV++ L KF+ S E ++ +LFDP +L +F+ E +
Sbjct: 1237 ILENLSSLKNENPSVLDWLMPLKFIHMSQEH---VVAASDLFDPDIEVLRDLFYNEEEAC 1293
Query: 1594 FPGERFSTDGWLRILRKLGLRTATEVDV--IIECAKRVEFLGIECMKSGDL 1642
FP F++ L LR++GL+ + +++ AK++E L + ++ D+
Sbjct: 1294 FPPAVFTSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEALQVSSCQNQDV 1344
Score = 53.5 bits (127), Expect = 6e-05
Identities = 108/468 (23%), Positives = 177/468 (37%), Gaps = 81/468 (17%)
Query: 144 LKLITWCPVILD--PAVRG-LPWLKSSKQVALPTVVRPKSQMWLVSSSMLILDGECGTTY 200
LK I W P + P G L W + P + + LV SS+ ++ E
Sbjct: 1372 LKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDAAHAVLVGSSLPLV--ESAHVS 1429
Query: 201 LQTKLGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDFDVKLQKEIPCLYSKLQEYIN 260
L+ LG P I + + ++ + KT S D D+ + Q + +Y + ++++
Sbjct: 1430 LEKTLGIFTKPTISAVLKHF-KIVVDWYTSKTFS--DEDY-YQFQHILLEIYGFMHDHLS 1485
Query: 261 T--DDFNDLKARLDGVSWVWIGDDFVSPNALAFDSPVK---FTPYLYVVSSELSEYKDLM 315
D F LK WVW G +F P A A P+ PYLY V ++++ L
Sbjct: 1486 EGKDSFKALK-----YPWVWTGKNFC-PLAQAVIKPIHDLDLQPYLYNVPKTMAKFHQLF 1539
Query: 316 IKLG---------------------------------VRLSFGILDYLHVLQRLQNDLNG 342
G + L I+ +L+ Q +
Sbjct: 1540 KACGSIEELTSDHISMVIQKVYLKSDQELSEEESKQNLHLMLNIMRWLYSNQIPASPNTP 1599
Query: 343 VPLSTDQLNFVRCVHEAIAECCLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLEN 402
VP+ + N + V + I ECC + + L +L+H D+ A WL+
Sbjct: 1600 VPIYHSK-NPSKLVMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHE-DIPMKTAEWLKV 1657
Query: 403 SSLIGRHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGYNKVSELLALYGNSEF 462
L R ++P E +G + S E +T ++ +L Y +
Sbjct: 1658 PCLSTR-LINP-------ENMGFEQ----SGQREPLTV--------RIKNILEEYPSVSD 1697
Query: 463 LLFDLLELADCCKAKKLHLIYDKREHP--RQSLLQHNLGEFQGPALVAIFEGACLSREEF 520
+ +LL+ AD A + + D R + R++LL + GPAL + F + S +F
Sbjct: 1698 IFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWS-FNNSEFSDSDF 1756
Query: 521 SNFQLLPPWKLRGNTLN---YGLGLVGCYSICDLLSVVSGGYFYMFDP 565
N L RG +GLG Y I D+ ++S + MFDP
Sbjct: 1757 INITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDP 1804
Score = 48.9 bits (115), Expect = 0.002
Identities = 56/279 (20%), Positives = 107/279 (38%), Gaps = 45/279 (16%)
Query: 1442 AQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPSNSFFKPHDEHCLSYATDSNGSSFL-- 1499
+Q++++IL+SLP YK++ G Y + C + + S P E + T S+ S+FL
Sbjct: 3621 SQDDLKILKSLPCYKSISGRYMSIAKFGTCYVLTKSI--PSAE--VEKWTQSSSSAFLEE 3676
Query: 1500 --------RALGVLELNDQQILVRFGLPGYERKSMNEQEDILIYVFKNWHDLQSNQSVVE 1551
LG + ++D ++ ++ LP E S + + + LIY+ ++ E
Sbjct: 3677 KVHLKELYEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLASIEELSETKE 3736
Query: 1552 ALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKKFPGERFS----------- 1600
L E + + LK + F + + E+ P E F
Sbjct: 3737 QLFEKLESLLIIHDANNRLKQAKHFYDRTVRVFEVMLPEKLFIPKEFFKKLEQVIKPKNQ 3796
Query: 1601 ---TDGWLRILRKLGLRTATEVDVIIECAKRVEFLGIECMKSGDLDDFEADTTNSRAEVS 1657
W+ LR +GL+ +++ AK + + +++ +T + ++
Sbjct: 3797 VVFMTSWVEFLRNIGLKHVLSQQQLLQFAKEISV-------RANTENWSKETLQNTVDI- 3848
Query: 1658 PEVWALGGSVVEFIFSNFALFFSNNFCDLLGKIAFVPSE 1696
++ IF S NF L I F+ E
Sbjct: 3849 ---------LLHHIFQERTDLLSGNFLKELSLIPFLCPE 3878
Score = 45.1 bits (105), Expect = 0.022
Identities = 38/168 (22%), Positives = 75/168 (44%), Gaps = 11/168 (6%)
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDF--VSPNALAFDSPVK-- 296
D ++ K + + E+++ + + + +L GV++V + D + + P + + +
Sbjct: 3983 DEEMVKTRAKVLRSIYEFLSAEK-REFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYEAD 4041
Query: 297 FTPYLYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCV 356
F PYLY + EL + L LG Y+ VL R+ + G L +++ V+ V
Sbjct: 4042 FKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRV 4101
Query: 357 HEAIAECC------LEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAP 398
+ + + L D L++P G L+ + LV++DAP
Sbjct: 4102 VSGLFKSLQNDSVKVRSDLENARDLALYLPSQDGRLVKSSILVFDDAP 4149
>ref|NP_056603.1| sacsin [Mus musculus] gi|6907044|gb|AAF31263.1| sacsin [Mus musculus]
gi|13124519|sp|Q9JLC8|SACS_MOUSE Sacsin
Length = 3830
Score = 128 bits (321), Expect = 2e-27
Identities = 206/963 (21%), Positives = 384/963 (39%), Gaps = 131/963 (13%)
Query: 10 KKMLHGDVFFPSDKFLDPEILDTLVCLGLRTTLG-FTGLLDCARSVS------------- 55
+K +VFFP+ + ++ E+ D L+ L L F+G+L V
Sbjct: 1303 EKQFFSEVFFPNIQEIEAELRDPLMNFVLNEKLDEFSGILRVTPCVPCSLEGHPLVLPSR 1362
Query: 56 LLHDSG------DTEASKHGKGLLV-FLDKLAC-KLSSNGESENDDQSLAVRSNITMDDA 107
L+H G DT+ + G +L+ + KL G +++D I DD
Sbjct: 1363 LIHPEGRVAKLFDTKDGRFPYGSTQDYLNPIILIKLVQLGMAKDD---------ILWDDM 1413
Query: 108 VVYDGFPKDENSLIDDVDLFMSSLINDMVEE----------EFWSELKLITWCPVILDPA 157
+ + N SS++ +++E +F ++ + I + P + PA
Sbjct: 1414 LERAESVAEINKSDHAAACLRSSILLSLIDEKLKIKDPRAKDFAAKYQTIPFLPFLTKPA 1473
Query: 158 VRGLPWLKSS---KQVALPTVVRPKSQMWLVSSSMLILDGE------CGTTYLQTK--LG 206
L W +S + + T + +V IL+ CG+ L K LG
Sbjct: 1474 GFSLEWKGNSFKPETMFAATDIYTAEYQDIVCLLQPILNENSHSFRGCGSVSLAVKEFLG 1533
Query: 207 WMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDFDVKLQKEIPCLYSKLQEYINTDDFND 266
+ P + ++ QL +++KS +D + + Y L E + ++
Sbjct: 1534 LLKKPTVDLVINQLKQVAKS---------VDDGITLYQENITNACYKYLHEAVLQNEMAK 1584
Query: 267 --LKARLDGVSWVWIGDDFVSPNALAFDSPVKFTPYLYVVSSEL-SEYKDLMIKLGVRLS 323
+ +L ++ + + +V ++F + PYLY + ++ + +++L +GVR S
Sbjct: 1585 ATIIEKLKPFCFILVENVYVESEKVSFHLNFEAAPYLYQLPNKYKNNFRELFESVGVRQS 1644
Query: 324 FGILDYLHVLQRLQNDLNGVPLSTDQLNFVR-CVHEAIAECCLEK--PLFEPFDSPLWIP 380
F + D+ VL+ + + ++ + R + E I EK E + +P
Sbjct: 1645 FTVEDFALVLESIDQERGKKQITEENFQLCRRIISEGIWSLIREKRQEFCEKNYGKILLP 1704
Query: 381 DTFGVLMHAGDLVYNDAPWLENSSLIGRHFVHPSISNDLAERLGVQSVRCLSLVSEDMTK 440
DT +L+ A L YND PW++ + + H I ++A +LG R +L
Sbjct: 1705 DTNLLLLPAKSLCYNDCPWIKVKDSTVK-YCHADIPREVAVKLGAIPKRHKALERYASNI 1763
Query: 441 DLPCMGY---------NKVSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQ 491
+G +++ +L Y + + +L +LL+ AD KA ++ ++D R+HP
Sbjct: 1764 CFTALGTEFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVD 1823
Query: 492 SLLQHNLGEFQGPALVAIFEGACLSREEFSNFQLLPPWKLRGN---TLNYGLGLVGCYSI 548
+ QGPAL ++ + ++ Q L GN T +YG+G Y I
Sbjct: 1824 RIFDDKWAPLQGPAL-CVYNNQPFTEDDVRGIQNLGKGTKEGNPCKTGHYGIGFNSVYHI 1882
Query: 549 CDLLSVVSGG-YFYMFDPRGLVLSAPSSNAPSGKMFSLIGTDLAQRFGDQFSPMLIDQND 607
D S +SG +FDP +S +P G+MF + D +F D L +
Sbjct: 1883 TDCPSFISGNDILGIFDPHARYAPGATSVSP-GRMFRDLDADFRTQFSDVLDLYL---GN 1938
Query: 608 LWSLSDSTIIRMPLSSDCLKVGHDVAS-----NRIKHITDVFMEHGSRTLLFLKSVLQVS 662
+ L + T+ R PL + + +++S ++++ D G+ L+FL + ++S
Sbjct: 1939 HFKLDNCTMFRFPLRNAEMAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKIS 1998
Query: 663 ISTWEE--GHSHPCQNFSISIDPSSSIMRNPFSEKKWRKFQLSRLFSSSNTAIKMHVIDV 720
I ++ G + + I + R F R + +D
Sbjct: 1999 ICEIDKATGGLNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDT 2058
Query: 721 SLYSEGTTFIDRWLLALSLGSGQ----TRNMALDRRYLAYNLTPVAGIAALISRN---GH 773
SEG + WL+ G ++++ + L P G+AA I+ N H
Sbjct: 2059 E-DSEGN--LTTWLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACITHNYKKPH 2115
Query: 774 HADVYSTSSIMTPLPLSGCINLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQL 833
A + LPLS LP V G F + R R L++ D G +
Sbjct: 2116 RAFCF--------LPLSLETGLPFHVNGHFALDSAR-RNLWR-----------DDNGVGV 2155
Query: 834 IELWNRELMSC-VCDSYVEMILEIQNL---RKDVSSSIIDSSACPGINLSLKAYGDNIYS 889
WN LM+ + +YVE++++++ D + S++ ++ + +LK + S
Sbjct: 2156 RSDWNNSLMTALIAPAYVELLIQLKKRYFPGSDPTLSVLQNTPIHVVKDTLKKF----LS 2211
Query: 890 FWP 892
F+P
Sbjct: 2212 FFP 2214
Score = 65.9 bits (159), Expect = 1e-08
Identities = 91/411 (22%), Positives = 173/411 (41%), Gaps = 74/411 (18%)
Query: 1253 PSSDSQGGPSSEWIKIFWKS-FRGSQEELSLFSDWPLIP-AFLGRPVLC----RVRERHL 1306
P S+ + PS W+K+ WK+ + E+L+LF + PLIP L C R+R +
Sbjct: 16 PFSEDKRHPSLSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTLLNEDQTCVELIRLRIPSV 75
Query: 1307 VFIPPPLVQRTLQSGILDRESTENHVGGVSVSRDDTSVAEAYTSAFDRLKISYPWLLSLL 1366
V + + L + D +GG+ + R DTS+ + + S L
Sbjct: 76 VILDDE-TEAQLPEFLAD---IVQKLGGIVLKRLDTSIQHPLVKKY---------IHSPL 122
Query: 1367 NQCNVPIFDEAFIDCATSSNCFSMPGGSLGQVIASKLVAAKQAGYFTEPNNLSASSCDAL 1426
+ I ++ +P L IAS L K A AS D
Sbjct: 123 PSAILQIMEK-------------IPLQKLCNQIASLLPTHKDA-----LRKFLASLTDT- 163
Query: 1427 FSLFCDELFSNGFHYAQEEIEILRSLPIYKTV-------VGSYTKLKDQDQCMIPSNSFF 1479
+++E I++ L I+K + + SYTKLK C + ++
Sbjct: 164 ---------------SEKEKRIIQELTIFKRINHSSDQGISSYTKLKG---CKVLDHTAK 205
Query: 1480 KPHDEHCLSYATDSNGSSFLRALGVLELNDQQIL--VRFGLPGYERKSMNEQE--DILIY 1535
P D DS+ + +R +L++ + ++F L ++E ++++
Sbjct: 206 LPTDLRLSVSVIDSSDEATIRLANMLKIEKLKTTSCLKFVLKDIGNAFYTQEEVTQLMLW 265
Query: 1536 VFKNWHDLQS-NQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKK- 1593
+ +N L++ N +V++ L KF+ S ++ +LFDP +L +F+ E +
Sbjct: 266 ILENLSSLKNENSNVLDWLMPLKFIHMSQGH---VVAAGDLFDPDIEVLRDLFYNEEEAC 322
Query: 1594 FPGERFSTDGWLRILRKLGLRTATEVDV--IIECAKRVEFLGIECMKSGDL 1642
FP F++ L LR++GL+ + + +++ A+++E L + ++ D+
Sbjct: 323 FPPTIFTSPDILHSLRQIGLKNESSLKEKDVVQVARKIEALQVSSCQNQDV 373
Score = 53.5 bits (127), Expect = 6e-05
Identities = 59/279 (21%), Positives = 109/279 (38%), Gaps = 45/279 (16%)
Query: 1442 AQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPSNSFFKPHDEHCLSYATDSNGSSFL-- 1499
+Q++I+IL+SLP YK++ G Y + C + + S P E + T S+ S+FL
Sbjct: 2650 SQDDIKILKSLPCYKSISGRYMSIAKFGTCYVLTKSI--PSAE--VEKWTQSSSSAFLEE 2705
Query: 1500 --------RALGVLELNDQQILVRFGLPGYERKSMNEQEDILIYVFKNWHDLQSNQSVVE 1551
LG + ++D ++ ++ LP E S + + + LIY+ ++ + E
Sbjct: 2706 KVHLKELYEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLASIEEPSEIKE 2765
Query: 1552 ALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKKFPGERFS----------- 1600
L E + + LK + F + + E+ P E F
Sbjct: 2766 QLFEKLESLLIIHDANNRLKQAKHFYDRTVRVFEVMLPEKLFIPKEFFKKLEQVIKPKNQ 2825
Query: 1601 ---TDGWLRILRKLGLRTATEVDVIIECAKRVEFLGIECMKSGDLDDFEADTTNSRAEVS 1657
W+ LR +GL+ A +++ AK + + +++ +T S ++
Sbjct: 2826 AAFMTSWVEFLRNIGLKYALSQQQLLQFAKEISV-------RANTENWSKETLQSTVDI- 2877
Query: 1658 PEVWALGGSVVEFIFSNFALFFSNNFCDLLGKIAFVPSE 1696
++ IF S NF L I F+ E
Sbjct: 2878 ---------LLHHIFQERMDLLSGNFLKELSLIPFLCPE 2907
Score = 49.7 bits (117), Expect = 0.001
Identities = 136/618 (22%), Positives = 222/618 (35%), Gaps = 140/618 (22%)
Query: 1 LYDPRVPELKKMLHGD--VFFPSDKFLDPEILDTLVCLGLR--TTLGFTGLLDCARSVSL 56
L+DP + L+ + + + FP F P+IL +L +GL+ ++L ++ AR +
Sbjct: 303 LFDPDIEVLRDLFYNEEEACFPPTIFTSPDILHSLRQIGLKNESSLKEKDVVQVARKIEA 362
Query: 57 LHDSGDTEAS---KHGKGLLVFLDKLACKLSSNGESENDDQSLAVRSNITMDDAVVYDGF 113
L S K K LL+ L+K +Q+L S M
Sbjct: 363 LQVSSCQNQDVLMKKAKTLLLVLNK--------------NQTLLQSSEGKM--------- 399
Query: 114 PKDENSLIDDVDLFMSSLINDMVEEEFWSELKLITWCPVILD--PAVRG-LPWLKSSKQV 170
LK I W P + P G L W +
Sbjct: 400 -----------------------------ALKKIKWVPACKERPPNYPGSLVWKGDLCNL 430
Query: 171 ALPTVVRPKSQMWLVSSSMLILDGECGTTYLQTKLGWMDCPNIGVLSRQLIELSKSYQQL 230
P + + LV SS+ ++ E L+ L P I + + + Y
Sbjct: 431 CAPPDMCDAAHAVLVGSSLPLV--ESVHVNLEQALSIFTKPTINAVLKHFKTVVDWYTS- 487
Query: 231 KTHSLLDPDFDVKLQKEIPCLYSKLQEYINT--DDFNDLKARLDGVSWVWIGDDFVSPNA 288
KT S D D+ + Q + +Y + ++++ D F LK WVW G +F P A
Sbjct: 488 KTFS--DEDY-YQFQHILLEIYGFMHDHLSEGKDSFKALK-----FPWVWTGKNFC-PLA 538
Query: 289 LAFDSP---VKFTPYLYVVSSELSEYKDLMIKLG-------------------------- 319
A P + PYLY V ++++ L G
Sbjct: 539 QAVIKPTHDLDLQPYLYNVPKTMAKFHQLFKACGSIEELTSDHISMVIQKVYLKSDQELS 598
Query: 320 -------VRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCVHEAIAECCLEKPLFEP 372
+ L I+ +L+ Q + VP+ + N + V + I ECC +
Sbjct: 599 EEESKQNLHLMLNIMRWLYSNQIPASPNTPVPIYHSR-NPSKLVMKPIHECCYCDIKVDD 657
Query: 373 FDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSLIGRHFVHPSISNDLAERLGVQSVRCLS 432
+ L +L+H D+ A WL+ L R ++P E +G + S
Sbjct: 658 LNDLLEDSVEPIILVHE-DIPMKTAEWLKVPCLSTR-LINP-------ENMGFEQ----S 704
Query: 433 LVSEDMTKDLPCMGYNKVSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHP--R 490
E +T ++ +L Y + + +LL+ AD A + + D R + R
Sbjct: 705 GQREPLTV--------RIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMDIR 756
Query: 491 QSLLQHNLGEFQGPALVAIFEGACLSREEFSNFQLLPPWKLRGNTLN---YGLGLVGCYS 547
++LL + GPAL + F + S +F N L RG +GLG Y
Sbjct: 757 ENLLDPGMAACHGPALWS-FNNSEFSDSDFLNITRLGESLKRGEVDKVGKFGLGFNSVYH 815
Query: 548 ICDLLSVVSGGYFYMFDP 565
I D+ ++S + MFDP
Sbjct: 816 ITDIPIIMSREFMIMFDP 833
Score = 45.1 bits (105), Expect = 0.022
Identities = 38/168 (22%), Positives = 74/168 (43%), Gaps = 11/168 (6%)
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDF--VSPNALAFDSPVK-- 296
D ++ K + + E+++ + + + +L GV++V + D + + P + + +
Sbjct: 3012 DEEMVKTRAKVLRSIYEFLSAEK-REFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYEAD 3070
Query: 297 FTPYLYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCV 356
F PYLY + EL + L LG Y+ VL R+ G L +++ V+ V
Sbjct: 3071 FKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKSSEGKQLDPNEMRTVKRV 3130
Query: 357 HEAIAECC------LEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAP 398
+ + + L D L++P G L+ + LV++DAP
Sbjct: 3131 VSGLFKSLQNDSVKVRSDLENARDLALYLPSQDGKLVKSSILVFDDAP 3178
>ref|XP_586753.1| PREDICTED: similar to sacsin, partial [Bos taurus]
Length = 2688
Score = 128 bits (321), Expect = 2e-27
Identities = 176/809 (21%), Positives = 327/809 (39%), Gaps = 90/809 (11%)
Query: 132 INDMVEEEFWSELKLITWCPVILDPAVRGLPWLKSSKQVALPTVVRPKSQMWLVSSSMLI 191
I D ++F + + I + P + PA L W +S + P + + +++ ++
Sbjct: 1469 IRDPRAKDFAATYQTIPFLPFLTKPAGFSLDWKGNSFK---PETMFAATDLYIAEHQDIV 1525
Query: 192 LDGE------------CGTTYLQTK--LGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLD 237
+ CG+ L K LG + P + ++ QL E++KS +D
Sbjct: 1526 CLLQPILNENSHSFRGCGSVPLAVKEFLGLLRKPTVELVVNQLREVAKS---------VD 1576
Query: 238 PDFDVKLQKEIPCLYSKLQEYINTDDFND--LKARLDGVSWVWIGDDFVSPNALAFDSPV 295
+ + Y L E + +D + +L S++ + + +V+ +AF
Sbjct: 1577 DGITLYQENITNACYKYLHEAMMQNDSTKTAVTEKLKTFSFILVENAYVNSEKVAFHLNF 1636
Query: 296 KFTPYLYVVSSEL-SEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVR 354
+ PYLY + ++ + +++L +GVR SF + D+ VL+ + + ++ + R
Sbjct: 1637 EAAPYLYQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIAQEKETKQVTEENFQLCR 1696
Query: 355 -CVHEAIAECCLEKP--LFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSLIGRHFV 411
+ E I EK E + +PDT L+ A L YND PW++ + +
Sbjct: 1697 RIISEGIWSLIREKKQEFCEKNYGHILLPDTNLKLLPAKSLCYNDCPWIKVKDSTVK-YC 1755
Query: 412 HPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGY---------NKVSELLALYGNSEF 462
H I ++A +LG R +L +G +++ +L Y + +
Sbjct: 1756 HADIPREVAVKLGAVPKRHKALERYASNVCFTTLGSEFGQKEKLTSRIKSILNAYPSEKE 1815
Query: 463 LLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSN 522
+L +LL+ AD KA ++ ++D R+HP + QGPAL ++ + ++
Sbjct: 1816 MLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPAL-CVYNNQPFTEDDVRG 1874
Query: 523 FQLLPPWKLRGN---TLNYGLGLVGCYSICDLLSVVSGG-YFYMFDPRGLVLSAPSSNAP 578
Q L GN T YG+G Y I D S +SG +FDP +S +P
Sbjct: 1875 IQNLGRGTKEGNPCKTGQYGVGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSVSP 1934
Query: 579 SGKMFSLIGTDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPLSSDCLKVGHDVAS---- 634
G+MF + D +F D L + L + T+ R PL + + +++S
Sbjct: 1935 -GRMFRDLDADFRTQFSDVLDLYL---GTHFKLDNCTMFRFPLRNAEMAKVSEISSVPSS 1990
Query: 635 -NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEE--GHSHPCQNFSISIDPSSSIMRNP 691
++++ D G+ L+FL + ++SI ++ G + + +I + R
Sbjct: 1991 DRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATGALNVLYSVKGNITDGDRLKRKQ 2050
Query: 692 FSEKKWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLALSLGSGQ----TRNM 747
F R + +D SEG+ + WL+ G ++++
Sbjct: 2051 FHASVIDSVTKKRQLPDIPVQQVTYTMDTE-DSEGS--LTSWLICNRSGFSSMDKVSKSV 2107
Query: 748 ALDRRYLAYNLTPVAGIAALISRNGHHADVYSTSSIMTPLPLSGCINLPVTVLGCFLVCH 807
+ L P G+AA I+ N + LPLS LP V G F +
Sbjct: 2108 VSAHKNQDITLFPRGGVAACITHN-----YKKPHRVFCFLPLSLETGLPFHVNGHFALDS 2162
Query: 808 NRGRYLFKYQDRRASAEGHFDAGNQLIELWNRELMSC-VCDSYVEMILEIQN---LRKDV 863
R R L++ D G + WN LM+ + +YVE++ +++ D
Sbjct: 2163 AR-RNLWR-----------DDNGVGVRSDWNSSLMTALIAPAYVELLAQLKKRYFSGSDP 2210
Query: 864 SSSIIDSSACPGINLSLKAYGDNIYSFWP 892
+ S++ S+ + +LK + SF+P
Sbjct: 2211 TLSVLQSTPIHVVKDTLKKF----LSFFP 2235
Score = 54.7 bits (130), Expect = 3e-05
Identities = 90/409 (22%), Positives = 165/409 (40%), Gaps = 90/409 (22%)
Query: 1253 PSSDSQGGPSSEWIKIFWKS-FRGSQEELSLFSDWPLIPAFL---GRPVLCRVRERHLVF 1308
P + + PS W+++ WK + E+L+LF + PLIP G+ + +R R
Sbjct: 37 PCDEDRKHPSVSWLRMVWKHLYVHFSEDLTLFDEMPLIPRTPLEEGQTCVELIRLR---- 92
Query: 1309 IPPPLVQRTLQSGILDRESTEN----------HVGGVSVSRDDTSVAEAYTSAFDRLKIS 1358
P LV ILD ES +GG+ + + D S+ + L S
Sbjct: 93 -APSLV-------ILDDESEAQLPEFLADVVQKLGGIVLKKLDASIQHPLIKKYIHLP-S 143
Query: 1359 YPWLLSLLNQCNVPIFDEAFIDCATSSNCFSMPGGSLGQVIASKLVAAKQAGYFTEPNNL 1418
+L ++ + MP L +AS L K A
Sbjct: 144 PSAVLHIMEK---------------------MPLQKLCNQVASLLPTHKDA--------- 173
Query: 1419 SASSCDALFSLFCDELFSNGFHYAQEEIEILRSLPIYKTV-------VGSYTKLKDQDQC 1471
+ +N +++E I++ L I+K + + SYT+LK C
Sbjct: 174 ------------LRKFLANLTESSEKEKRIIQELTIFKRINHSSSQGLSSYTRLKG---C 218
Query: 1472 MIPSNSFFKPHDEHCLSYATDSNGSSFLRALGVLELNDQQIL--VRFGLPGYERKSMNEQ 1529
+ + P DS+ + +R +L++ + ++ L E +++
Sbjct: 219 RVLHPAATLPAGLRLSISVVDSSDEATIRLANLLKVEKVRTTSCLKLILKDIESTFYSQE 278
Query: 1530 E--DILIYVFKNWHDLQS-NQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISI 1586
E ++++V +N L+S N +V++ L KF++ L+ ELFDP +L +
Sbjct: 279 EVTHLVLWVLENLSSLKSENPNVLDWLTPLKFIQLPPG---RLVMASELFDPDIEVLKDL 335
Query: 1587 FFGERKK-FPGERFSTDGWLRILRKLGLRTATEVDV--IIECAKRVEFL 1632
F+ E + FP F++ L LR++GL+ + +++ AK++E L
Sbjct: 336 FYDEEEACFPPSAFTSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEAL 384
Score = 50.1 bits (118), Expect = 7e-04
Identities = 106/468 (22%), Positives = 177/468 (37%), Gaps = 81/468 (17%)
Query: 144 LKLITWCPVILD--PAVRG-LPWLKSSKQVALPTVVRPKSQMWLVSSSMLILDGECGTTY 200
LK I W P + P G L W ++ P + + LV SS+ ++ E
Sbjct: 422 LKKIKWVPACKERPPNYPGSLVWKGDLCELCAPPDMCDAAHAILVGSSLPLV--ESVHVN 479
Query: 201 LQTKLGWMDCPNIGVLSRQLIELSKSYQQLKTHSLLDPDFDVKLQKEIPCLYSKLQEYIN 260
L+ LG + P I + + ++ + KT S D D+ + Q + +Y + +++N
Sbjct: 480 LEKALGILTKPGINAVLKHF-KIVVDWYTSKTFS--DEDY-YQFQHILLEIYGFMHDHLN 535
Query: 261 T--DDFNDLKARLDGVSWVWIGDDFVSPNALAFDSP---VKFTPYLYVVSSELSEYKDLM 315
D F LK WVW G F P A A P + PYL+ V ++++ L
Sbjct: 536 EGKDAFRALK-----FPWVWTGKKFC-PLAQAVIKPFHDLDLQPYLHSVPKTMAKFHQLF 589
Query: 316 IKLG---------------------------------VRLSFGILDYLHVLQRLQNDLNG 342
G + L I+ +L+ Q +
Sbjct: 590 KACGSIEELTADHISMVIQKVYLKSDQDLSDQESKQNLHLMLNIIRWLYSNQIPASPNTP 649
Query: 343 VPLSTDQLNFVRCVHEAIAECCLEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLEN 402
VP+ + N + + + I ECC + + L +L+H D+ A WL+
Sbjct: 650 VPIHHSK-NPSKLIMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHE-DIPMKTAEWLKV 707
Query: 403 SSLIGRHFVHPSISNDLAERLGVQSVRCLSLVSEDMTKDLPCMGYNKVSELLALYGNSEF 462
L R ++P E +G + S E +T ++ +L Y +
Sbjct: 708 PCLSTR-LINP-------ENMGFEQ----SGQREPLTV--------RIKNILEEYPSVSD 747
Query: 463 LLFDLLELADCCKAKKLHLIYDKREHP--RQSLLQHNLGEFQGPALVAIFEGACLSREEF 520
+ +LL+ AD A + + D R + R++LL + GPAL + F + S +F
Sbjct: 748 IFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWS-FNNSQFSDSDF 806
Query: 521 SNFQLLPPWKLRGNTLN---YGLGLVGCYSICDLLSVVSGGYFYMFDP 565
N L R +GLG Y I D+ ++S + MFDP
Sbjct: 807 VNITRLGESLKRAEVDKVGKFGLGFNSVYHITDIPVIMSREFMIMFDP 854
Score = 45.1 bits (105), Expect = 0.022
Identities = 37/126 (29%), Positives = 62/126 (48%), Gaps = 21/126 (16%)
Query: 1442 AQEEIEILRSLPIYKTVVGSYTKLKDQDQCMIPSNSFFKPHDEHCLSYATDSNGSSFL-- 1499
+Q++I+IL+SLP YK++ G Y + C + + S P E + T S+ S+FL
Sbjct: 2544 SQDDIKILKSLPCYKSISGRYMSIAKFGTCYVLTKSI--PSAE--VEKWTQSSSSAFLEE 2599
Query: 1500 --------RALGVLELNDQQILVRFGLPGYERKSMNEQEDILIYVFKNWHDLQSNQSVVE 1551
LG + ++D ++ ++ LP E S + + + LIY L++ S VE
Sbjct: 2600 KIHLKELYELLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIY-------LKNRLSNVE 2652
Query: 1552 ALKETK 1557
L E K
Sbjct: 2653 ELSEIK 2658
>emb|CAE45964.1| hypothetical protein [Homo sapiens]
Length = 731
Score = 79.0 bits (193), Expect = 1e-12
Identities = 135/617 (21%), Positives = 243/617 (38%), Gaps = 89/617 (14%)
Query: 452 ELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAIFE 511
++L Y +L +L++ A+ A ++ +YD+ ++ ++L ++ +QGPAL ++
Sbjct: 1 DILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAPYQGPALY-VYN 59
Query: 512 GACLSREEFSNFQLLPPWKLRGNTL---NYGLGLVGCYSICDLLSVVSGGYFYMFDPRGL 568
A + E++ Q + + + + L +G+G Y I D+ + SG M DP
Sbjct: 60 NAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPHQT 119
Query: 569 VLSAPSSNAPSGKMFSL-IGTDLAQRFGDQFSPML-----IDQNDLWSLSDSTIIRMPLS 622
+ SG+ ++L + DQF+P + + + T R PL
Sbjct: 120 LFGPHE----SGQCWNLKDDSKEISELSDQFAPFVGIFGSTKETFINGNFPGTFFRFPLR 175
Query: 623 SDCLKVGHDVAS-NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEEGHSHPCQNFSISI 681
++ ++ + ++ + + F LLFLKSV VS+ E + F ++
Sbjct: 176 LQPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQDVSLYVREADGTEKLV-FRVTS 234
Query: 682 DPSSSIMRNPFSEKKWRKFQLS---RLFSSSNTAIKMHVIDVSLYSEGTTFIDR--WLLA 736
S ++ + K +S + S+N + +++ L E T + WL+
Sbjct: 235 SESKALKHERPNSIKILGTAISNYCKKTPSNNITCVTYHVNIVLEEESTKDAQKTSWLVC 294
Query: 737 LSLGSGQTRNMALDRRYLAYNLTPVAGIAALIS-----RNGHHADVYSTSSIMTPLP--L 789
S+G G+ + LD P+ GIA +S G +D + PLP
Sbjct: 295 NSVG-GRGISSKLDSLADELKFVPIIGIAMPLSSRDDEAKGATSDFSGKAFCFLPLPPGE 353
Query: 790 SGCINLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNREL-MSCVCDS 848
LPV + G F + N RR+ D LWN L M+ V +
Sbjct: 354 ESSTGLPVHISGFFGLTDN----------RRSIKWRELDQWRDPAALWNEFLVMNVVPKA 403
Query: 849 YVEMILE-IQNLRKDVSSSIIDSSACPGINLSLKAYGDNIYSFWPRSSEGHVPSGQLFDH 907
Y +IL+ I+ L + SS LS+ D IY WP +S+
Sbjct: 404 YATLILDSIKRLEMEKSSD---------FPLSV----DVIYKLWPEASK----------- 439
Query: 908 NNTPSSSTAVLKADWECLKERVIHPFYSRIVDLPVWQLYSGNLVKAGEGMFLSQPGNGMI 967
+K W + V+ P +S ++ V S + V+ + F N
Sbjct: 440 ----------VKVHW----QPVLEPLFSELLQNAVIYSISCDWVRLEQVYFSELDENLEY 485
Query: 968 GSLLPGTVCSFVKEHYPVFSVPWELVTEIQVVGFS----VREVRPKMVRDLLKVSSKPIV 1023
+ + S K+ + VP + +Q+ S VR+V P VR +L+ K
Sbjct: 486 TKTVLNYLQSSGKQ---IAKVPGNVDAAVQLTAASGTTPVRKVTPAWVRQVLR---KCAH 539
Query: 1024 LRSVDMYIDVLEYCLSN 1040
L + + +LE+ LS+
Sbjct: 540 LGCAEEKLHLLEFVLSD 556
>ref|XP_595962.1| PREDICTED: similar to spastic ataxia of Charlevoix-Saguenay
(sacsin), partial [Bos taurus]
Length = 794
Score = 73.6 bits (179), Expect = 6e-11
Identities = 111/491 (22%), Positives = 185/491 (37%), Gaps = 61/491 (12%)
Query: 450 VSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNLGEFQGPALVAI 509
+ ++L Y +L +L++ A+ A ++ +YD+ ++ Q+L ++ ++QGPAL +
Sbjct: 134 LKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTQTLWSKDMAQYQGPALY-V 192
Query: 510 FEGACLSREEFSNFQLLPPWKLRGNTL---NYGLGLVGCYSICDLLSVVSGGYFYMFDPR 566
+ A + E++ Q + + + + L +G+G Y I D+ + SG M DP
Sbjct: 193 YNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPH 252
Query: 567 GLVLSAPSSNAPSGKMFSLIGTDLAQRFGDQFSPMLIDQNDLWSLSDSTIIRMPLSSDCL 626
+ S K S + A G S + + T R PL
Sbjct: 253 QTLFGPRESGQDDSKEISELSYQFAPFIGLFGS---TKETFVKGSFPGTFFRFPLRRQPS 309
Query: 627 KV-GHDVASNRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEEGHSHPCQNFSISIDPSS 685
++ G ++ + + F LLFLK+V VS+ E S + +P++
Sbjct: 310 QLSGTLYNKQKVLELFESFQADADTVLLFLKNVQDVSLHVREADGSEKLVFRVTAREPAA 369
Query: 686 SIMRNPFSEKKWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFID---------RWLLA 736
P E+ L S + + Y D WL+
Sbjct: 370 -----PAPERPGAVEALGAALSDYCERVPSGGVTCVTYPVSIVLEDGDAQGARETSWLVC 424
Query: 737 LSLGSGQTRNMALDRRYLAYNLTPVAGIAALIS--RNGHHADVYSTSSI-MTPLP--LSG 791
S+G G+ + LD PV GIA +S H A +S + PLP
Sbjct: 425 NSVG-GRGLSAQLDALADELRFVPVIGIATPLSGLAEEHGAAGFSGKAFCFLPLPPGEES 483
Query: 792 CINLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNREL-MSCVCDSYV 850
LPV V G F + N RR+ D +WN L +S V +Y
Sbjct: 484 RTGLPVHVSGFFGLTDN----------RRSIKWRELDQWRDPAAVWNELLVLSVVPRAYA 533
Query: 851 EMILE-IQNLRKDVSSSIIDSSACPGINLSLKAYGDNIYSFWPRSSEGHVP--------S 901
+IL+ + LR S PG+ LS+ +Y WP +++ +P
Sbjct: 534 ALILDAVARLRAGCS---------PGLPLSVA----GVYGLWPDAAQVKLPWRPALEPLF 580
Query: 902 GQLFDHNNTPS 912
+LF H PS
Sbjct: 581 QELFQHEVLPS 591
>dbj|BAC30083.1| unnamed protein product [Mus musculus]
Length = 719
Score = 65.9 bits (159), Expect = 1e-08
Identities = 91/411 (22%), Positives = 173/411 (41%), Gaps = 74/411 (18%)
Query: 1253 PSSDSQGGPSSEWIKIFWKS-FRGSQEELSLFSDWPLIP-AFLGRPVLC----RVRERHL 1306
P S+ + PS W+K+ WK+ + E+L+LF + PLIP L C R+R +
Sbjct: 16 PFSEDKRHPSLSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTLLNEDQTCVELIRLRIPSV 75
Query: 1307 VFIPPPLVQRTLQSGILDRESTENHVGGVSVSRDDTSVAEAYTSAFDRLKISYPWLLSLL 1366
V + + L + D +GG+ + R DTS+ + + S L
Sbjct: 76 VILDDE-TEAQLPEFLAD---IVQKLGGIVLKRLDTSIQHPLVKKY---------IHSPL 122
Query: 1367 NQCNVPIFDEAFIDCATSSNCFSMPGGSLGQVIASKLVAAKQAGYFTEPNNLSASSCDAL 1426
+ I ++ +P L IAS L K A AS D
Sbjct: 123 PSAILQIMEK-------------IPLQKLCNQIASLLPTHKDA-----LRKFLASLTDT- 163
Query: 1427 FSLFCDELFSNGFHYAQEEIEILRSLPIYKTV-------VGSYTKLKDQDQCMIPSNSFF 1479
+++E I++ L I+K + + SYTKLK C + ++
Sbjct: 164 ---------------SEKEKRIIQELTIFKRINHSSDQGISSYTKLKG---CKVLDHTAK 205
Query: 1480 KPHDEHCLSYATDSNGSSFLRALGVLELNDQQIL--VRFGLPGYERKSMNEQE--DILIY 1535
P D DS+ + +R +L++ + ++F L ++E ++++
Sbjct: 206 LPTDLRLSVSVIDSSDEATIRLANMLKIEKLKTTSCLKFVLKDIGNAFYTQEEVTQLMLW 265
Query: 1536 VFKNWHDLQS-NQSVVEALKETKFVRNSDEFSTDLLKPKELFDPADAILISIFFGERKK- 1593
+ +N L++ N +V++ L KF+ S ++ +LFDP +L +F+ E +
Sbjct: 266 ILENLSSLKNENSNVLDWLMPLKFIHMSQGH---VVAAGDLFDPDIEVLRDLFYNEEEAC 322
Query: 1594 FPGERFSTDGWLRILRKLGLRTATEVDV--IIECAKRVEFLGIECMKSGDL 1642
FP F++ L LR++GL+ + + +++ A+++E L + ++ D+
Sbjct: 323 FPPTIFTSPDILHSLRQIGLKNESSLKEKDVVQVARKIEALQVSSCQNQDV 373
>ref|XP_647016.1| hypothetical protein DDB0190084 [Dictyostelium discoideum]
gi|60475079|gb|EAL73015.1| hypothetical protein
DDB0190084 [Dictyostelium discoideum]
Length = 2673
Score = 58.5 bits (140), Expect = 2e-06
Identities = 96/471 (20%), Positives = 196/471 (41%), Gaps = 44/471 (9%)
Query: 252 YSKLQEYINTDDFND-LKARLDGVSWVWIGDDFVSPNALAFDSP---VKFTPYLYVVSSE 307
Y ++ + I T ND K ++ + +W+ V + ++SP + F PY ++
Sbjct: 1120 YKRIDDLIKTSKLNDEQKKKISQIQLIWLDGQLVPKEKIFYNSPNPNLDFKPYFFITKPT 1179
Query: 308 LSE-YKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCVHEAIAECCLE 366
+K L +K L+ D++ +++ +Q+ + S++ ++ V ++
Sbjct: 1180 QEHLFKFLKLKEIPDLN----DFIRLIKSIQDTYDKE--SSNSIDLFELVIYSLQNPAFN 1233
Query: 367 KPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSL-IGRHFVHPSISNDLAERLGV 425
K L DS + +P T + ++Y D L + +G +H IS + A +L +
Sbjct: 1234 KELL--IDSKIKLPTTDNQFVEFEKVIYIDHSCLPQEFIDLGHSALHNKISENTASKLSI 1291
Query: 426 QSVRCL--SLVSEDMTKDLPCMGYNKVSELLALYGNSEFLLFDLLELADCCKAKKLHLIY 483
+ L S V+ + + +++ ++L Y E L ++++ A + ++ LI
Sbjct: 1292 TKLSQLIQSQVAFENSFGQKEELVDRLKQILRDY-KVEVFLNEMVQNAHDAGSTEVKLIL 1350
Query: 484 D--------KREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSNFQLLPPW--KLRG 533
D +E+P S L +L + +L+ + + + ++ N Q++ K
Sbjct: 1351 DCNSLKQQFLKENPEISTLCKDLPSYFESSLL-FYNNSVFTEKDIKNVQVMSASIKKQDE 1409
Query: 534 NTLN-YGLGLVGCYSICDLLSVVSGGYFYMFDPRGLVLSAPSSNAPSGKMFSLIGTDLAQ 592
N++ +GLG+ YS D ++SG Y +FDP + S N G + + +
Sbjct: 1410 NSIGQHGLGINSMYSFSDCPCILSGEYLMIFDP-FVTHIGQSINYSHGAKYKI---SEYK 1465
Query: 593 RFGDQFSPMLIDQNDL-WSLSD----STIIRMPLSSDCLKVGHDVASNRIKHITDV---- 643
F F P Q+ L + L D TIIR+PL L ++ + + +
Sbjct: 1466 TFLKYFKPFQHLQSILGFDLDDGKFNGTIIRLPLRK-TLNDDRFISPQKWNEVNVLDYLK 1524
Query: 644 -FMEHGSRTLLFLKSVLQVSISTWEEGHSHPCQNFSISIDPSSSIMRNPFS 693
L+F ++ + +S G Q SI + S S++ N ++
Sbjct: 1525 RVKASNLENLMFFTNIDSLEVSILPVGSKKLEQQISIHKESSLSLITNQYN 1575
Score = 42.7 bits (99), Expect = 0.11
Identities = 90/444 (20%), Positives = 171/444 (38%), Gaps = 50/444 (11%)
Query: 439 TKDLPCMGYNKVSELLALYGNSEFLLFDLLELADCCKAKKLHLIYDKREHPRQSLLQHNL 498
TKD + + L Y S+ ++ +L++ A+ A + D+ +P LL N
Sbjct: 4 TKDQRLKVSHSLRNNLLNYPESK-IVRELIQNAEDALADTFIIKVDEGSYPNNGLLISND 62
Query: 499 G-------EFQGPALVAIFEGACLSREEFSNFQLLPPWKLRGNTL---NYGLGLVGCYSI 548
E GP+++ I+ A +++ + + N N+GLG Y I
Sbjct: 63 NQEIESSKELLGPSIL-IYNNATFHEQDWEGICEINQGSKKENLKSVGNFGLGWNSVYHI 121
Query: 549 CDLLSVVSGGYFYMFDPRGLVLSAPSSNAPSGKMFSLIGTDLAQR---FGDQFSPMLIDQ 605
D V SG + D P+ G F L D + F + F
Sbjct: 122 TDNPIVYSGNNVWFAD--------PNERIGGGLFFDLDDEDDYNKCFSFLEPFIQFKESN 173
Query: 606 NDLWSLSDSTIIRMPLSSDCLKVGHDVAS-NRIKHITDVFMEHGSRTLLFLKSVLQVSIS 664
+ + TIIR+PL ++ V + + IK I + F + + L+FLKS+ ++I
Sbjct: 174 CNPKEYFNGTIIRLPLRIYPSEIKKAVLTMDAIKKILNEFSKDINEILIFLKSLASITII 233
Query: 665 TWEE-GHSHPCQNFSISIDPSSSI-----------MRNPFSEKKWRKFQLSRLFSSSNTA 712
+ +S +N+S D + M NP S + + S S +
Sbjct: 234 VNNQIVNSVKIKNYSKIKDQREKVSLFLSKIVDNEMNNPSSAVELAEILCSN--KSQSNC 291
Query: 713 IKMHVIDVSLYSEGTTFIDRWLLALSLGSGQTRNMALDRRYLAYNLTPVAGIAALISRNG 772
ID+ +Y G + + +L++ + + + + L ++ L G+A IS +
Sbjct: 292 ESTFQIDLEIYRNGVSQLISYLVSQGIYIDR-KLIELVKKNKEIKLISYGGVAVPISLD- 349
Query: 773 HHADVYSTSSIMTPLPLSGCI-NLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGN 831
+ + T LP+ + ++P+ V G F + + R ++ + +A
Sbjct: 350 --SSINFKGKPFTFLPIGALVYDIPLHVNGYFRLSNARDNIIYSLTEVE-------EASE 400
Query: 832 QLIELWNRELMSCVCDSYVEMILE 855
L + WN+ + + + LE
Sbjct: 401 SLSKQWNKFISETIIPYFYVKSLE 424
>ref|NP_766397.1| hypothetical protein LOC239128 [Mus musculus]
gi|26338143|dbj|BAC32757.1| unnamed protein product [Mus
musculus]
Length = 531
Score = 53.9 bits (128), Expect = 5e-05
Identities = 106/448 (23%), Positives = 171/448 (37%), Gaps = 79/448 (17%)
Query: 615 TIIRMPLSSDCLKVGHDV-ASNRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEEGHSHP 673
T R PL ++ ++ ++ + D F LLFLKSV VS+ E +
Sbjct: 56 TFFRFPLRLQPSQLSSNLYTKQKVLELFDSFRADADTVLLFLKSVQAVSLHVREADGTEK 115
Query: 674 CQNFSISIDPSSSIMRNPFSEKKWRKFQLS----RLFSSSNTAIKMHVIDVSLYSEGTTF 729
F ++ + ++ + K +S ++ S+S T + H I++ L E T
Sbjct: 116 LV-FRVTASENKALKHERPNSIKILGTAISNYCKKIPSNSVTCVTYH-INIVLEDESTKD 173
Query: 730 IDR--WLLALSLGSGQTRNMALDRRYLAYNLTPVAGIAALIS----RNGHHADVYSTSSI 783
+ WL+ S+G G+ + LD P+ G+A +S NG +D +
Sbjct: 174 AQKTSWLVCNSVG-GRGISSKLDSLADELKFVPIIGLAMPLSGKDEENGAISDFSGKAFC 232
Query: 784 MTPLP--LSGCINLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNREL 841
PLP LPV + G F + N RR+ D LWN L
Sbjct: 233 FLPLPPGEESRTGLPVHISGFFGLTDN----------RRSIKWRELDQWRDPAALWNEYL 282
Query: 842 -MSCVCDSYVEMILE-IQNLRKDVSSSIIDSSACPGINLSLKAYGDNIYSFWPRSSEGHV 899
++ V +Y +IL+ I+ L + SS LS+ D IY WP +S+
Sbjct: 283 IVNVVPKTYATLILDSIKRLETEKSSD---------FPLSV----DTIYKLWPEASK--- 326
Query: 900 PSGQLFDHNNTPSSSTAVLKADWECLKERVIHPFYSRIVDLPVWQLYSGNLVKAGEGMFL 959
+KA W V+ P +S + V G VK + F
Sbjct: 327 ------------------VKAHW----HPVLGPLFSELFQHAVIYSIGGEWVKLEQVHFS 364
Query: 960 SQPGNGMIGSLLPGTVCSFVKEHYPVFSVPWELVTEIQVVGFS-------VREVRPKMVR 1012
G+ + + S K+ + VP L +Q+ S VR+V P VR
Sbjct: 365 ELDGSLESTRSVLNYLQSSGKQ---IAKVPGNLAAAVQLSAASATSSASPVRKVTPAWVR 421
Query: 1013 DLLKVSSKPIVLRSVDMYIDVLEYCLSN 1040
+L+ K L S + + +LE+ LS+
Sbjct: 422 QVLR---KCAHLGSAEEKLHLLEFVLSD 446
>ref|XP_647014.1| hypothetical protein DDB0190082 [Dictyostelium discoideum]
gi|60475077|gb|EAL73013.1| hypothetical protein
DDB0190082 [Dictyostelium discoideum]
Length = 2660
Score = 51.2 bits (121), Expect = 3e-04
Identities = 65/334 (19%), Positives = 146/334 (43%), Gaps = 30/334 (8%)
Query: 252 YSKLQEYINTDDF--NDLKARLDGVSWVWIGDDFVSPNALAFDSP---VKFTPYLYVVSS 306
Y ++ I T+ ++ K ++ + +W+ V + ++SP + F PY +
Sbjct: 1102 YKRIDSLIFTNSILNDEQKKKISQIQLIWLDGQLVPKENIFYNSPNPNLDFEPYFFFTKP 1161
Query: 307 ELSE-YKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCVHEAIAECCL 365
+ +K L +K L+ D++ +++ +Q+ + S++ ++ V ++ L
Sbjct: 1162 KQDHLFKFLKLKDKPDLN----DFIRLIKSIQDTYDKD--SSNSIDLFELVIFSLQNSAL 1215
Query: 366 EKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSL-IGRHFVHPSISNDLAERLG 424
K L +S + +P T + ++Y D L + +G +H IS + A +L
Sbjct: 1216 NKELL--LNSKIKLPTTDNQFIEFEKVIYVDHSCLPQEFIDLGHSALHNKISENTASKLN 1273
Query: 425 VQSVRCL--SLVSEDMTKDLPCMGYNKVSELLALYGNSEFLLFDLLELADCCKAKKLHLI 482
+ + L S V+ D + +++ ++L Y E L ++++ A + ++ LI
Sbjct: 1274 ITKLSQLIQSQVAFDNSFGQKEELVDRLKQILHDY-KVEVFLNEMVQNAHDAGSTEVKLI 1332
Query: 483 YD--------KREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSNFQLLPPWKLRGN 534
D +E+P S + +L + +L+ + + + ++ N Q++ + +
Sbjct: 1333 LDCNSLKQQFLKENPEISTVCKDLSSYFESSLL-FYNNSVFTEKDIKNVQVMSASIKKQD 1391
Query: 535 TL---NYGLGLVGCYSICDLLSVVSGGYFYMFDP 565
+GLG+ YS D ++SG Y +FDP
Sbjct: 1392 EKCIGQHGLGINSMYSFSDCPCILSGEYLMIFDP 1425
Score = 46.6 bits (109), Expect = 0.008
Identities = 85/402 (21%), Positives = 158/402 (39%), Gaps = 54/402 (13%)
Query: 466 DLLELADCCKAKKLHLIYDKREHPRQSLLQHNLG-------EFQGPALVAIFEGACLSRE 518
+L++ A+ +A + + D+ +P LL N E GP+++ I+ A
Sbjct: 30 ELIQNAEDARADTVIIKVDEGSYPNNGLLISNDNQEIESSKELLGPSIL-IYNNATFQEH 88
Query: 519 EFSNFQLLPPWKLRGNTL---NYGLGLVGCYSICDLLSVVSGGYFYMFDPRGLVLSAPSS 575
++ + + N N+GLG Y I D V SG + D P+
Sbjct: 89 DWEGICQISQGSKKENLKSVGNFGLGWNSVYHITDNPIVYSGNNVWFSD--------PNE 140
Query: 576 NAPSGKMFSLIGTDLAQR---FGDQFSPMLIDQNDLWSLSDSTIIRMPLSSDCLKVGHDV 632
G F L D ++ F + F + + TIIR+PL ++ V
Sbjct: 141 RMSGGLFFDLDDEDDYKKCFSFLEPFIQFKESNCNPKEYFNGTIIRLPLRIFPSEIKKGV 200
Query: 633 AS-NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEE-GHSHPCQNFSISIDPSSSI--- 687
+ + IK I + F + + L+FLKS+ ++I + +S N+S D +
Sbjct: 201 LTMDAIKKILNEFSKDINEILIFLKSLASITIIVNNQIVNSVNISNYSKIKDQREKVSLF 260
Query: 688 --------MRNPFSEKKWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLALSL 739
M++P S ++ + S+ S + ID+ +Y G + + +L+
Sbjct: 261 LAKIVDNEMKDPSSSVEFAEILCSK--KSQSNCESTFQIDLEIYRNGVSQLISYLV---- 314
Query: 740 GSGQTRNMALDRRYLAYNLTPVAGIAALISRNGHHADVYSTSSI------MTPLPLSGCI 793
++ + +DR+ + L LIS G + SSI T LP+ G +
Sbjct: 315 ----SQGIYIDRKLI--ELVKKNKEIKLISYGGTAIPINLDSSIKFKGKPFTFLPIGGLV 368
Query: 794 -NLPVTVLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLI 834
++P+ V G F + + R ++ + ++E N I
Sbjct: 369 YDIPLHVNGYFRLSNARDNIIYSLTEVEEASESLSKQWNMFI 410
>ref|XP_647015.1| hypothetical protein DDB0190083 [Dictyostelium discoideum]
gi|60475078|gb|EAL73014.1| hypothetical protein
DDB0190083 [Dictyostelium discoideum]
Length = 2661
Score = 49.7 bits (117), Expect = 0.001
Identities = 69/336 (20%), Positives = 143/336 (42%), Gaps = 35/336 (10%)
Query: 252 YSKLQEYINTDDFND-LKARLDGVSWVWIGDDFVSPNALAFDSP---VKFTPYLYVVSSE 307
Y ++ I ND K ++ + +W+ V + ++SP + F PY +V +
Sbjct: 1101 YKEIDYLIKNFKLNDEQKKKISQIQLIWLDGQLVPKEKIFYNSPNPNLDFKPYFFVTKPK 1160
Query: 308 LSE-YKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCVHEAIAECCLE 366
+K L +K L+ D++ +++ +Q+ ++ +L F ++ L+
Sbjct: 1161 QEHLFKFLKLKDKPDLN----DFIRLIKSIQDTYEKESSNSIEL-FELVIYS------LQ 1209
Query: 367 KPLFEP---FDSPLWIPDTFGVLMHAGDLVYNDAPWLENSSL-IGRHFVHPSISNDLAER 422
P F DS + +P T + ++Y D L + +G +H IS + A +
Sbjct: 1210 NPAFNKESLIDSKIKLPTTDNQFVEFEKVIYVDHSCLPQEFIDLGHSALHNKISENTASK 1269
Query: 423 LGVQSVRCL--SLVSEDMTKDLPCMGYNKVSELLALYGNSEFLLFDLLELADCCKAKKLH 480
L + + L S V+ D + +++ ++L Y E L ++++ A + ++
Sbjct: 1270 LNIIKLSQLIQSQVAFDHSFGQKEDLVDRLKQILNDY-KVEVFLNEMVQNAHDAGSTEVK 1328
Query: 481 LIYD--------KREHPRQSLLQHNLGEFQGPALVAIFEGACLSREEFSNFQLLPPWKLR 532
LI D +E+P S L +L + +L+ + + + ++ N Q + +
Sbjct: 1329 LILDCNSLKQQFLKENPEISTLCKDLPSYFESSLL-FYNNSVFTDDDIKNVQAMTASIKK 1387
Query: 533 GNTL---NYGLGLVGCYSICDLLSVVSGGYFYMFDP 565
+ +GLG+ YS D ++SG Y +FDP
Sbjct: 1388 QDEKCIGQHGLGINSMYSFSDCPCILSGEYLMIFDP 1423
Score = 45.1 bits (105), Expect = 0.022
Identities = 91/465 (19%), Positives = 171/465 (36%), Gaps = 71/465 (15%)
Query: 466 DLLELADCCKAKKLHLIYDKREHPRQSLLQHNLG-------EFQGPALVAIFEGACLSRE 518
+L++ A+ +A + + D+ +P LL N E GP+++ I+ A +
Sbjct: 30 ELIQNAEDARADTVIIKVDEGSYPNNGLLISNDNQEIQSSKELLGPSIL-IYNNATFQKH 88
Query: 519 EFSNFQLLPPWKLRGNTL---NYGLGLVGCYSICDLLSVVSGGYFYMFDPRGLVLSAPSS 575
++ + + N N+GLG Y I D V SG + D P+
Sbjct: 89 DWEGICQISQGSKKENLKSVGNFGLGWNSVYHITDNPIVYSGNNVWFAD--------PNE 140
Query: 576 NAPSGKMFSLIGTDLAQR---FGDQFSPMLIDQNDLWSLSDSTIIRMPLSSDCLKVGHDV 632
G F L D + F + F + + TIIR+PL ++ V
Sbjct: 141 RMSGGLFFDLDDEDDYNKCLSFLEPFIQFKESNCNPKEYFNGTIIRLPLRIYPSEIKKAV 200
Query: 633 AS-NRIKHITDVFMEHGSRTLLFLKSVLQVSISTWEE-GHSHPCQNFSISIDPSSSI--- 687
+ + IK I + F + + L+FLKS+ ++I + +S N+S + +
Sbjct: 201 LTMDAIKKILNEFSKDINEILIFLKSLASITIIVNNQIINSVSISNYSKIKEKREKVSLF 260
Query: 688 --------MRNPFSEKKWRKFQLSRLFSSSNTAIKMHVIDVSLYSEGTTFIDRWLLALSL 739
M NP S + + S S + ID+ +Y G + + +L++ +
Sbjct: 261 LANIVDNEMNNPSSAVELAEILCSN--KSQSNCESTFQIDLEIYRNGASQLISYLVSQGI 318
Query: 740 GSGQTRNMALDRRYLAYNLTPVAGIAALISRNGHHADVYSTSSIMTPLPLSGCI-NLPVT 798
+ + + L ++ L G+A IS +G + T LP+ + ++P+
Sbjct: 319 YIDR-KLIELVKKNKEIKLISYGGVAVPISLDG---PINFKGKPFTFLPIGALVYDIPLH 374
Query: 799 VLGCFLVCHNRGRYLFKYQDRRASAEGHFDAGNQLIELWNRELMSCVCDSYVEMILEIQN 858
V G F + + R ++ + +A L + WN + + + LE
Sbjct: 375 VNGYFRLSNARDNIIYSLTEVE-------EASESLSKQWNMFISETIIPYFYVKSLEYLK 427
Query: 859 LRKDVSSSIIDSSACPGINLSLKAYGDNIYSFWPRSSEGHVPSGQ 903
L YG +Y+++P GQ
Sbjct: 428 LN----------------------YGGELYNYFPYKCNNQNYQGQ 450
>dbj|BAD32289.1| mKIAA0730 protein [Mus musculus]
Length = 1024
Score = 45.1 bits (105), Expect = 0.022
Identities = 38/168 (22%), Positives = 74/168 (43%), Gaps = 11/168 (6%)
Query: 241 DVKLQKEIPCLYSKLQEYINTDDFNDLKARLDGVSWVWIGDDF--VSPNALAFDSPVK-- 296
D ++ K + + E+++ + + + +L GV++V + D + + P + + +
Sbjct: 206 DEEMVKTRAKVLRSIYEFLSAEK-REFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYEAD 264
Query: 297 FTPYLYVVSSELSEYKDLMIKLGVRLSFGILDYLHVLQRLQNDLNGVPLSTDQLNFVRCV 356
F PYLY + EL + L LG Y+ VL R+ G L +++ V+ V
Sbjct: 265 FKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKSSEGKQLDPNEMRTVKRV 324
Query: 357 HEAIAECC------LEKPLFEPFDSPLWIPDTFGVLMHAGDLVYNDAP 398
+ + + L D L++P G L+ + LV++DAP
Sbjct: 325 VSGLFKSLQNDSVKVRSDLENARDLALYLPSQDGKLVKSSILVFDDAP 372
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.320 0.138 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,079,642,496
Number of Sequences: 2540612
Number of extensions: 136694608
Number of successful extensions: 279689
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 279414
Number of HSP's gapped (non-prelim): 162
length of query: 1754
length of database: 863,360,394
effective HSP length: 142
effective length of query: 1612
effective length of database: 502,593,490
effective search space: 810180705880
effective search space used: 810180705880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 83 (36.6 bits)
Lotus: description of TM0237.14