BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0237.12
(2349 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
dbj|BAB09828.1| unnamed protein product [Arabidopsis thaliana] g... 3091 0.0
ref|XP_474331.1| OSJNBa0018M05.18 [Oryza sativa (japonica cultiv... 2721 0.0
emb|CAG02848.1| unnamed protein product [Tetraodon nigroviridis] 462 e-128
ref|XP_417138.1| PREDICTED: similar to sacsin [Gallus gallus] 448 e-123
emb|CAI13923.1| spastic ataxia of Charlevoix-Saguenay (sacsin) [... 442 e-122
ref|NP_055178.2| sacsin [Homo sapiens] 395 e-108
emb|CAH18265.1| hypothetical protein [Homo sapiens] 305 2e-80
ref|XP_534533.1| PREDICTED: similar to sacsin [Canis familiaris] 299 9e-79
gb|AAF31262.1| sacsin [Homo sapiens] gi|13124523|sp|Q9NZJ4|SACS_... 291 2e-76
ref|NP_056603.1| sacsin [Mus musculus] gi|6907044|gb|AAF31263.1|... 282 9e-74
ref|XP_224256.3| PREDICTED: similar to sacsin [Rattus norvegicus] 282 9e-74
emb|CAE45964.1| hypothetical protein [Homo sapiens] 251 2e-64
emb|CAG09278.1| unnamed protein product [Tetraodon nigroviridis] 251 3e-64
ref|XP_586753.1| PREDICTED: similar to sacsin, partial [Bos taurus] 240 5e-61
ref|XP_595962.1| PREDICTED: similar to spastic ataxia of Charlev... 229 9e-58
ref|XP_647015.1| hypothetical protein DDB0190083 [Dictyostelium ... 139 9e-31
ref|XP_647016.1| hypothetical protein DDB0190084 [Dictyostelium ... 131 3e-28
ref|XP_647014.1| hypothetical protein DDB0190082 [Dictyostelium ... 131 3e-28
ref|NP_766397.1| hypothetical protein LOC239128 [Mus musculus] g... 124 4e-26
dbj|BAC03486.1| unnamed protein product [Homo sapiens] 98 4e-18
>dbj|BAB09828.1| unnamed protein product [Arabidopsis thaliana]
gi|15237223|ref|NP_197702.1| zinc finger (C3HC4-type RING
finger) family protein [Arabidopsis thaliana]
Length = 4706
Score = 3091 bits (8014), Expect = 0.0
Identities = 1532/2349 (65%), Positives = 1860/2349 (78%), Gaps = 17/2349 (0%)
Query: 7 ESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDS 66
+S+ LEDFGQ VDLTRRIREVLLNYPEGTTVLKELIQNADDAGAT V LCLDRR H S
Sbjct: 2 DSLLLEDFGQKVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATKVRLCLDRRVHGSGS 61
Query: 67 LLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTD 126
LLS SL+QWQGP+LLAYNDAVFTE+DF+SIS+IGGS KHGQA KTGRFGVGFNSVYHLTD
Sbjct: 62 LLSDSLAQWQGPSLLAYNDAVFTEEDFVSISRIGGSGKHGQAWKTGRFGVGFNSVYHLTD 121
Query: 127 LPSFVSGKYVVLFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSP 186
+PSFVSGKYVVLFDPQG YLP +SAANPGKRID+ GSSALS YKDQF PYCAFGCDM+SP
Sbjct: 122 IPSFVSGKYVVLFDPQGAYLPNISAANPGKRIDYVGSSALSQYKDQFLPYCAFGCDMRSP 181
Query: 187 FAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVW 246
F GTLFRFPLRN +QA+ S+LSRQAY +DIS MF QLFEEGV +LLFLK VL IEMY W
Sbjct: 182 FNGTLFRFPLRNTEQAASSRLSRQAYFEDDISLMFDQLFEEGVFSLLFLKCVLSIEMYTW 241
Query: 247 DAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSK-SLNTTTEVDAFPLEFVTEAVRGVET 305
D G+ +PKK++SCSVSS ++DT+WHRQA+LRLSK S++ E+DAF LEF++E+ +G +T
Sbjct: 242 DDGDSEPKKLYSCSVSSPNNDTVWHRQAVLRLSKTSISGDREMDAFTLEFLSESEKGNQT 301
Query: 306 VRQVDRFYIVQTMASASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTGQA 365
R+ DRFYIVQTMASASS+IG FA TASKEYDI LLPWAS+AACISD+S N++L+ G A
Sbjct: 302 KRRTDRFYIVQTMASASSKIGLFAATASKEYDIHLLPWASVAACISDDSSENNILKLGHA 361
Query: 366 FCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVH 425
FCFLPLPVRTGL+VQVNG+FEVSSNRRGIWYG+DMDRSGKVRS WNRLLLED+VAP+F
Sbjct: 362 FCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKVRSAWNRLLLEDVVAPSFAR 421
Query: 426 MLHGVKELLGPTDIYYSLWPTGSFEEPWSILVQQIYINICNAPVIYSNLGGGRWVSPSEA 485
+L ++E+L D Y+SLWP+GSFE PWSILV+QIY NICNAPV++S+L GG+WVSP++A
Sbjct: 422 LLLCLREVLDSRDSYFSLWPSGSFEAPWSILVEQIYKNICNAPVLFSDLDGGKWVSPADA 481
Query: 486 FLHDEKFTKSKDLSLALMQLGMPVVHLPNSLFDMLLKYNS---SKVITPGTVRQFLRECE 542
+LHDE+F+ SKDL AL+QL MP+V LP +FDMLLK+ S KV+TP VR FL+EC+
Sbjct: 482 YLHDEEFSGSKDLGDALLQLEMPIVCLPRLVFDMLLKHPSFLLPKVVTPDRVRNFLKECK 541
Query: 543 SCNHLSRAHKLLLLEYCLEDLVDDDVGKAAYNLPLLPLANGNFASFLEASKGIPYFICDE 602
+ + L ++ KL+LLEYCL+DL DD V A NL LLPLANG+F F + + YFICDE
Sbjct: 542 TLSALKKSLKLVLLEYCLDDLTDDSVCTQASNLKLLPLANGDFGFFSGRTGSVSYFICDE 601
Query: 603 LEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSNTNIALFSIHHFAHLFPVFMPDDWKYK 662
LE+ LL+ V DRVID++IPP + TRL IA S N+A+FSIH+ LFP +P +WK++
Sbjct: 602 LEHMLLQKVYDRVIDKNIPPPLYTRLFAIAESRTANVAIFSIHNLLQLFPRLVPAEWKHR 661
Query: 663 CKVFWDPDSCQK-PTSSWFVLFWQYLGKQSEILPLFKDWPILPSTSGHLLRPSRQLKMIN 721
K+ W P+S + P+SSWFVLFWQYL K+ + L LF DWPILPSTSG+L S Q K+IN
Sbjct: 662 SKISWHPESNRDHPSSSWFVLFWQYLDKRCQSLSLFCDWPILPSTSGYLYIASPQSKLIN 721
Query: 722 GSTLSDTVQDILVKIGCHILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSS-AENMQV 780
L V+++L KIG IL VEH DL S++ + GVLESIF+A SS + +Q
Sbjct: 722 AEKLPAAVRNVLEKIGGKILNNNIKVEHSDLSSFVSDASYTGVLESIFDAASSDLDGVQN 781
Query: 781 SFSSLIAEERNELRRFLLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLEN 840
L A+E++ELR FLLDP+W++GH + + +R C+ LPI+++Y Q+S++SDL N
Sbjct: 782 LIYDLNAQEKDELRSFLLDPKWHIGHQIGDLYLRICKILPIHRIYGETSAQESKYSDLVN 841
Query: 841 PRKYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQA 900
P K+LPPLDVP +L G EFI+ +EED+LSRYYG+ERM K+ FY+++VF+R+ LQ
Sbjct: 842 PPKHLPPLDVPACLL-GCEFILCCQGSEEDVLSRYYGIERMRKSNFYRQNVFNRIEVLQP 900
Query: 901 EDRDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLE 960
E RD +M+S+LQ+LP L LED +R+ L+NL+F+PTV G LK PSVL+DPRNEE+YALLE
Sbjct: 901 EIRDQVMISILQDLPQLCLEDRLLREELQNLEFVPTVNGPLKRPSVLHDPRNEELYALLE 960
Query: 961 DSDSFPSGVFRESETLDIMRGLGLKTSVSPDTVLESARCIEHLMHEDQQKAYLKGKVLFS 1020
DSD FP+ F+ S LD+++GLGLKT+VSP+T+LESAR +E LMH+D +KA+ +GKVLFS
Sbjct: 961 DSDCFPASGFQGSAILDMLQGLGLKTTVSPETILESARLVERLMHKDLEKAHSRGKVLFS 1020
Query: 1021 YLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPVLVSP 1080
+LEVNA+KWLPD+ + GA+NRI S+AATAFR RN ++ KFW++L++I WCPVLVS
Sbjct: 1021 FLEVNAVKWLPDQSSEDDGAINRIFSRAATAFRPRNLTCNLVKFWSELKMICWCPVLVSA 1080
Query: 1081 PFHSLPWPVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLGWMCPPGGGVI 1140
PF +LPWPVV+S VAPPK+VRP D+WLVSA MRILDGECSSTAL Y LGW+ PGG I
Sbjct: 1081 PFQTLPWPVVTSTVAPPKLVRPKTDMWLVSASMRILDGECSSTALAYNLGWLSHPGGSAI 1140
Query: 1141 AAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVKAVLEGCRWIWVGD 1200
AAQLLELGKNNEI+ DQVLRQELALAMP+IYSIL ++GSDE++IVKAVLEG RWIWVGD
Sbjct: 1141 AAQLLELGKNNEILIDQVLRQELALAMPKIYSILARLLGSDEMDIVKAVLEGSRWIWVGD 1200
Query: 1201 GFATSDEVVLDGPLHLAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFRMANKKG 1260
GFAT EVVLDGPL L PYIRVIP DLAVF+ LF+ELG+REFL PSDY ++L R+A +KG
Sbjct: 1201 GFATLSEVVLDGPLQLVPYIRVIPTDLAVFRGLFVELGVREFLTPSDYADVLCRIAVRKG 1260
Query: 1261 SSPLDTQEIRAVMLIVHHLAEVYLHGQKVQLYLPDVSGRLFLAGDLVYNDAPWLLGSEDP 1320
+SPLD QEIRA +LI LAE KV +YLPDVSGRLF + DLVYNDAPWL S++
Sbjct: 1261 TSPLDPQEIRAAVLIAQQLAEAQFL-DKVTIYLPDVSGRLFPSSDLVYNDAPWLTASDNL 1319
Query: 1321 DGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAESADSMNFGLSGAAE 1380
+ SF ++ NAKRT+QKFVHGNISN+VAEKLGVRSLRR+LLAESADSMNF LSGAAE
Sbjct: 1320 NSSFSAESTMLLNAKRTMQKFVHGNISNEVAEKLGVRSLRRVLLAESADSMNFSLSGAAE 1379
Query: 1381 AFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLDKSQYGTSSVLSPEM 1440
AFGQHEALTTRLKHILEMYADGPG LFELVQNAEDAGASEV FLLDK+ YGTSS+LSPEM
Sbjct: 1380 AFGQHEALTTRLKHILEMYADGPGILFELVQNAEDAGASEVTFLLDKTHYGTSSLLSPEM 1439
Query: 1441 ADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVS 1500
ADWQGPALYCFN+SVFT QD+YAISRIGQ SKLEK FAIGRFGLGFNCVYHFTDIP FVS
Sbjct: 1440 ADWQGPALYCFNNSVFTQQDMYAISRIGQASKLEKPFAIGRFGLGFNCVYHFTDIPGFVS 1499
Query: 1501 GENIVMFDPHASNLPGISPSHPGLRIKFAGRKILEQFPDQFSSLLHFGCDLQHPFPGTLF 1560
GENIVMFDPHA++LPGISP+HPGLRIKFAGR IL+QFPDQF+ LHFGCDL+H FPGTLF
Sbjct: 1500 GENIVMFDPHANHLPGISPTHPGLRIKFAGRYILDQFPDQFAPFLHFGCDLEHTFPGTLF 1559
Query: 1561 RFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISIFLKEGTGHE 1620
RFPLR A VA RS IKKE Y PEDV SLF +FS VVSE L+FLRNVK++SIF KEG GHE
Sbjct: 1560 RFPLRNASVAPRSHIKKETYAPEDVLSLFTSFSGVVSEALIFLRNVKTVSIFTKEGAGHE 1619
Query: 1621 MRLLHRVSRASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLSLSIDRDLPYKCQK 1680
M+LLHRV + + VF+ E+ GMN+ Q LKKLS ++ +DLPYKCQK
Sbjct: 1620 MQLLHRVCKDHNVGQDTEPKPSSQVFSLLDENIFAGMNKDQLLKKLSNTVVKDLPYKCQK 1679
Query: 1681 ILITEQGTHGRNSHYWIMTECLGGGNVLKGTSEASTSNSHNFVPWACVAAYLNSVKHGED 1740
I++TEQ + G H WI ECL G K + S H +PWA VA ++NSVK+
Sbjct: 1680 IVVTEQDSSGCILHGWITGECLNAGVSKKNLNLPEMS--HKLIPWASVAVHINSVKN--- 1734
Query: 1741 LVDSAEVEDDCLVSSDLFQFASLPMHPRENFEGRAFCFLPLPISTGLPAHVNAYFELSSN 1800
VED S++F +++ + R NF GRAFCFLPLPI+TGLPAH+NAYFELSSN
Sbjct: 1735 ----ENVEDLAASISNIFGPSTISIQNRRNFGGRAFCFLPLPITTGLPAHINAYFELSSN 1790
Query: 1801 RRDIWFGSDMTGGGRKRSDWNIYLLENVVAPAYGRLLEKVALEIGPCYLFFSLWPKTLGL 1860
RRD+WFG+DM G G+ RSDWN+YL+E VV PAYG LLEK+A E+GPC LFFS+WP TLG
Sbjct: 1791 RRDLWFGNDMAGDGKVRSDWNLYLIEEVVVPAYGHLLEKIASELGPCDLFFSVWPVTLGT 1850
Query: 1861 EPWASVIRKLYQFVAEFNLRVLYTEARGGQWISTKHAIFPDFSFPKADELIKALSGASLP 1920
EPWAS++RKLY F+A LRVLYT+ARGGQWISTK AI+PDFSFPKADEL+ L+ A LP
Sbjct: 1851 EPWASLVRKLYSFIANNGLRVLYTKARGGQWISTKQAIYPDFSFPKADELVDVLADAGLP 1910
Query: 1921 VITLPQSLLERFMEICPSLHFLKPKLLRTLLIRRKREFKDRDAMILTLEYCLHDFEESMQ 1980
VI + +++ ERF E C SLH + P+LLRTLL RRKREF+DR+ + L LEYCL D +
Sbjct: 1911 VINISKTVAERFGEACSSLHLMTPQLLRTLLTRRKREFRDRNGLALALEYCLLDLKVPFL 1970
Query: 1981 FDTLGGLPLLPLADGSFTSIEMKGIGERVYIARGDEYGLLRDSIPHQLVDCVIPKEVHRK 2040
D L GLPLLPLADGSFT+ G ER++ A Y LL+DS+PHQLVD +P+ V+ K
Sbjct: 1971 ADLLYGLPLLPLADGSFTTFNKNGTAERIFFAEEIGYELLKDSLPHQLVDREVPEGVYSK 2030
Query: 2041 LCYIAQTDSTNISFLSCQLLEKLLVKLLPVEWQHASLVSWTPGIHGQPSLEWLQLLWNYL 2100
L +AQ+ + I LSC LLEKL KLLP +W + + WTPG G P++EW+++LW+YL
Sbjct: 2031 LLAVAQSGESCICLLSCNLLEKLFFKLLPADWHLSEKILWTPGQRGHPTVEWIRVLWSYL 2090
Query: 2101 KANCDDLLMFSKWPILPVGDDCLIQLKPNLNVIKNDGWSEKMSSLLVKVGCLFLRPDLQL 2160
K +CDDL +FSKWPILPV D CL+QL N NVI++DGWSE MSSLL+K GC FL +L +
Sbjct: 2091 KLSCDDLSVFSKWPILPVEDGCLMQLILNSNVIRDDGWSENMSSLLLKCGCRFLNRELPV 2150
Query: 2161 DHPKLECFVQSPTARGVLNVFLAVAGEPQKIEGIFTDASDGELHELRSFILQSKWFSEEQ 2220
+HP+LE FVQ PTA G+LN LA++G + I+GIF + S+GELHELR+FILQSKWFS
Sbjct: 2151 EHPQLETFVQPPTATGILNALLAISGGHENIKGIFLNVSEGELHELRNFILQSKWFSGGH 2210
Query: 2221 IDRSHVETIKHLPMFESYKSRKLVSLIKPIKWLGPTGVGEDLLNDSFIRTESDMERVIMR 2280
++ H ETIKHLP+FESY+SRKLVSL P+KWL P G+ EDLL+D F+R +S+ ER I +
Sbjct: 2211 MNEVHFETIKHLPIFESYRSRKLVSLNCPVKWLKPDGIREDLLDDDFVRLDSERERTIFK 2270
Query: 2281 RYLEIKEPTRVEFYKDHIFNRMSEFLLKPEVVSSILNDVQLLIKEDISLKSSLSAVSFVL 2340
RYL+IKEP+++EFYK + NRMSEFL + E + +IL+D+ L+ D+SL+ ++S FVL
Sbjct: 2271 RYLQIKEPSKMEFYKACVLNRMSEFLSQQEALLAILHDLNDLVVADVSLQCAISTTPFVL 2330
Query: 2341 AADGSWQQP 2349
AA+G WQQP
Sbjct: 2331 AANGLWQQP 2339
Score = 832 bits (2148), Expect = 0.0
Identities = 622/2110 (29%), Positives = 981/2110 (46%), Gaps = 269/2110 (12%)
Query: 12 EDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSS 71
E FGQ LT R++ +L Y +G +L EL+QNA+DAGA+ V+ LD+ + SLLS
Sbjct: 1379 EAFGQHEALTTRLKHILEMYADGPGILFELVQNAEDAGASEVTFLLDKTHYGTSSLLSPE 1438
Query: 72 LSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFV 131
++ WQGPAL +N++VFT+ D +IS+IG +SK + GRFG+GFN VYH TD+P FV
Sbjct: 1439 MADWQGPALYCFNNSVFTQQDMYAISRIGQASKLEKPFAIGRFGLGFNCVYHFTDIPGFV 1498
Query: 132 SGKYVVLFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTL 191
SG+ +V+FDP +LP +S +PG RI F G L + DQF+P+ FGCD++ F GTL
Sbjct: 1499 SGENIVMFDPHANHLPGISPTHPGLRIKFAGRYILDQFPDQFAPFLHFGCDLEHTFPGTL 1558
Query: 192 FRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAG-- 249
FRFPLRNA A RS + ++ Y PED+ S+F L+FL++V + ++ +
Sbjct: 1559 FRFPLRNASVAPRSHIKKETYAPEDVLSLFTSFSGVVSEALIFLRNVKTVSIFTKEGAGH 1618
Query: 250 ------------------EPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAF 291
EPKP S V S+ D+ I+ +L K L+ T D
Sbjct: 1619 EMQLLHRVCKDHNVGQDTEPKP----SSQVFSLLDENIFAGMNKDQLLKKLSNTVVKD-L 1673
Query: 292 PLEFVTEAVRGVETVRQVDRFYIVQTMASASSRIGSFAITASKEYDIQLLPWASIAACIS 351
P + V ++ + +I +A + + E +L+PWAS+A I
Sbjct: 1674 PYKCQKIVVTEQDSSGCILHGWITGECLNAGVSKKNLNLP---EMSHKLIPWASVAVHI- 1729
Query: 352 DNSLNNDVLRT-----------------------GQAFCFLPLPVRTGLSVQVNGFFEVS 388
NS+ N+ + G+AFCFLPLP+ TGL +N +FE+S
Sbjct: 1730 -NSVKNENVEDLAASISNIFGPSTISIQNRRNFGGRAFCFLPLPITTGLPAHINAYFELS 1788
Query: 389 SNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHMLHGVKELLGPTDIYYSLWPTGS 448
SNRR +W+G+DM GKVRS WN L+E++V PA+ H+L + LGP D+++S+WP
Sbjct: 1789 SNRRDLWFGNDMAGDGKVRSDWNLYLIEEVVVPAYGHLLEKIASELGPCDLFFSVWPVTL 1848
Query: 449 FEEPWSILVQQIYINICN--APVIYSNLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQLG 506
EPW+ LV+++Y I N V+Y+ GG+W+S +A D F K+ +L L G
Sbjct: 1849 GTEPWASLVRKLYSFIANNGLRVLYTKARGGQWISTKQAIYPDFSFPKADELVDVLADAG 1908
Query: 507 MPVVHLPNSLFDMLLKYNSS-KVITPGTVRQFL----RECESCNHLSRAHKLLLLEYCLE 561
+PV+++ ++ + + SS ++TP +R L RE N L+ L LEYCL
Sbjct: 1909 LPVINISKTVAERFGEACSSLHLMTPQLLRTLLTRRKREFRDRNGLA-----LALEYCLL 1963
Query: 562 DLVDDDVGKAAYNLPLLPLANGNFASFLEASKGIPYFICDELEYKLL-EPVSDRVIDQSI 620
DL + Y LPLLPLA+G+F +F + F +E+ Y+LL + + +++D+ +
Sbjct: 1964 DLKVPFLADLLYGLPLLPLADGSFTTFNKNGTAERIFFAEEIGYELLKDSLPHQLVDREV 2023
Query: 621 PPNILTRLSGIAMSSNTNIALFSIHHFAHLFPVFMPDDWKYKCKVFWDPDSCQKPTSSWF 680
P + ++L +A S + I L S + LF +P DW K+ W P PT W
Sbjct: 2024 PEGVYSKLLAVAQSGESCICLLSCNLLEKLFFKLLPADWHLSEKILWTPGQRGHPTVEWI 2083
Query: 681 VLFWQYLGKQSEILPLFKDWPILPSTSGHLLRPSRQLKMINGSTLSDTVQDILVKIGCHI 740
+ W YL + L +F WPILP G L++ +I S+ + +L+K GC
Sbjct: 2084 RVLWSYLKLSCDDLSVFSKWPILPVEDGCLMQLILNSNVIRDDGWSENMSSLLLKCGCRF 2143
Query: 741 LKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEERNELRRFLLDP 800
L VEHP L +++ A G+L ++ EN++ F ++ E +ELR F+L
Sbjct: 2144 LNRELPVEHPQLETFVQPPTATGILNALLAISGGHENIKGIFLNVSEGELHELRNFILQS 2203
Query: 801 QWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKYLPPLDVPEFILVGIEF 860
+W+ G M+E + + LPI++ Y + + L P K+L P + E +L +F
Sbjct: 2204 KWFSGGHMNEVHFETIKHLPIFESY-----RSRKLVSLNCPVKWLKPDGIREDLLDD-DF 2257
Query: 861 IVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSIMLSVLQNLPLLSLE 920
+ S E I RY ++ K +FYK V +R+ E ++ +L++L +L L +
Sbjct: 2258 VRLDSERERTIFKRYLQIKEPSKMEFYKACVLNRMSEFLSQQE--ALLAILHDLNDLVVA 2315
Query: 921 DASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLEDSDSFPSGVFRESETLDIMR 980
D S++ + F+ G + PS LYDPR + LL FPS F +S+ LD +
Sbjct: 2316 DVSLQCAISTTPFVLAANGLWQQPSRLYDPRVPALQELLHKEVYFPSEKFSDSKILDALV 2375
Query: 981 GLGLKTSVSPDTVLESARCIEHLMHEDQQKAYLKGKVLFSYLEVNALKWLPDKFDDKKGA 1040
GLGL+T++ T L++AR + L +A G+ L ++ K L K K G
Sbjct: 2376 GLGLRTTLDCSTYLDAARSVSMLHDLGDLEASRYGRRLLFHI-----KTLSIKLSSKTGE 2430
Query: 1041 VNRILSQAATAFRSRN---------------------TKSDIEKFWNDLQLISWCPVLVS 1079
N SQ + S + T+ ++FW L+ I WCP+ +
Sbjct: 2431 ANHDESQNIMSITSEDSFDGETYPEYETETSYLGSLLTQQSEDEFWCQLRSIPWCPICLD 2490
Query: 1080 PPFHSLPWPVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLGWMCPPGGGV 1139
PP +PW S++VA P VRP + ++LVSA M +LDGEC S+ L LGWM +
Sbjct: 2491 PPIEGIPWLESSNLVASPDRVRPKSQMFLVSATMHLLDGECQSSYLHQKLGWMDCLTIDI 2550
Query: 1140 IAAQLLELGKN-----NEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVKAVLEGCR 1194
+ QL+E+ K+ + + L +P +Y+ L + ++ +K+ L G
Sbjct: 2551 LCRQLIEISKSYKEQKSRSSVNPEFESMLQSQIPLLYTRLQELSRENDFLALKSALSGVP 2610
Query: 1195 WIWVGDGFATSDEVVLDGPLHLAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFR 1254
W+W+GD F ++D + D P+ PY+ V+P +L+ FK L LELG+R +DY+N L
Sbjct: 2611 WVWLGDDFVSADVLSFDSPVKFTPYLYVVPSELSDFKELLLELGVRLSFDAADYMNTLQH 2670
Query: 1255 MANKKGSSPLDTQEIRAVMLIVHHLA----EVYLHGQKVQLYLPDVSGRLFLAGDLVYND 1310
+ N S L ++I V+ ++ +A EV + +PD +G L DLVYND
Sbjct: 2671 LQNDIKGSQLTDEQINFVLCVLEAVADCFSEVSSDSDNNSVLVPDSAGFLVPLEDLVYND 2730
Query: 1311 APWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAESADS 1370
APW+ S + + KR FVH +I++D+A +LG++SLR + L ++ +
Sbjct: 2731 APWV-------------DSSSLSGKR----FVHPSINSDMANRLGIQSLRCISLVDNDIT 2773
Query: 1371 MNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLDKSQY 1430
+ T+LK +L +YA LF+L++ A+ ++ + DK ++
Sbjct: 2774 QDLPCMDF-----------TKLKELLSLYASKDFLLFDLLELADCCKVKKLHIIFDKREH 2822
Query: 1431 GTSSVLSPEMADWQGPALYCFNDSV-FTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCV 1489
++L + ++QGPA+ + V T +++ ++ + Q + +GLG
Sbjct: 2823 PRKTLLQHNLGEFQGPAIVAILEGVTLTREEICSLQLLSQWRIKGETL---NYGLGLLSC 2879
Query: 1490 YHFTDIPMFVSGENIVMFDPHASNLPGISPSHP-GLRIKFAGRKILEQFPDQFSSLLHFG 1548
Y D+ VSG MFDP + L + P G G ++E+F DQF+ +L
Sbjct: 2880 YFMCDLLSIVSGGYFYMFDPQGATLSASTTQAPAGKMFSLIGTNLVERFSDQFNPMLIGQ 2939
Query: 1549 CDLQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKS 1608
T+ R PL T +I K+ + A V + FL N
Sbjct: 2940 DKAWSLTDSTIIRMPLST-------EILKDGFE--------AGLDRVKQISDQFLENASR 2984
Query: 1609 ISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFNFFKEDRLVGMNRA---QFLKK 1665
I IFLK VS+ S E G+A+ + + M + LK
Sbjct: 2985 ILIFLKS-----------VSQVSFSTWEQGNAQPHQDYTLHIDSASAIMRNPFAEKNLKT 3033
Query: 1666 LSLSIDRDLPYKCQKILITEQGTH-GRNS--HYWIMTECLGGG---NVLKGTSEASTSNS 1719
LS K I E H G N W++ G G N+ +G +
Sbjct: 3034 SKLSRIFGSSNSGVKSRIIEVNLHIGENKLLDRWLVVLSKGSGQSQNMARGRKYLA---- 3089
Query: 1720 HNFVPWACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMHPRENFEGRAFCFL 1779
+N P A VAA+++ D+ AS M P L
Sbjct: 3090 YNLTPVAGVAAHVSRNGRPVDV-----------------HAASPIMSP-----------L 3121
Query: 1780 PLPISTGLPAHVNAYFELSSNRRDIWFGS---------DMTGGGRKRSDWNIYLLENVVA 1830
PL S LP + F + +N F + + G WN L+ + V
Sbjct: 3122 PLSGSVNLPVTILGCFLIRNNCGRFLFKNKNERAMSEPQLDAGDILIDAWNKELM-SCVR 3180
Query: 1831 PAYGRL---LEKVALEIGPC------------------YLFFSLWPKTLG---------L 1860
+Y + +E+++ E + +S WP++ L
Sbjct: 3181 DSYIEIVVEMERLSREHSSSSTESSTARQLALSLKAYGHQLYSFWPRSNQHDDAIEAEVL 3240
Query: 1861 EP-WA----SVIRKLYQFVAEFNLRVLYTEARGGQWISTKHAIFPDFSFPKADELIKALS 1915
+P W VIR Y VA+ L LY+ G + + +F + P ++ + L
Sbjct: 3241 KPEWECLVEQVIRPFYARVADLPLWQLYS----GSLVKAEEGMF--LTQPGSEVAVNLLP 3294
Query: 1916 -------GASLPVITLPQSLLERFMEICPSLHFLKPKLLRTLLIRRKR--EFKDRDAMIL 1966
PV ++P LL + + +KPK++R LL + + + D I
Sbjct: 3295 LTVCSFVKEHYPVFSVPWELLAEVQAVGIPVREVKPKMVRVLLRKSSASIDLRSVDTFID 3354
Query: 1967 TLEYCLHDFE 1976
LEYCL D +
Sbjct: 3355 VLEYCLSDIQ 3364
Score = 107 bits (266), Expect = 6e-21
Identities = 134/597 (22%), Positives = 236/597 (39%), Gaps = 72/597 (12%)
Query: 23 RIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSLSQWQGPALLA 82
+++E+L Y +L +L++ AD + + D+R H +LL +L ++QGPA++A
Sbjct: 2783 KLKELLSLYASKDFLLFDLLELADCCKVKKLHIIFDKREHPRKTLLQHNLGEFQGPAIVA 2842
Query: 83 YNDAV-FTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVSGKYVVLFDP 141
+ V T ++ S+ + G+ T +G+G S Y + DL S VSG Y +FDP
Sbjct: 2843 ILEGVTLTREEICSLQLLSQWRIKGE---TLNYGLGLLSCYFMCDLLSIVSGGYFYMFDP 2899
Query: 142 QGVYLPRVSAANP-GKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTLFRFPLRNAD 200
QG L + P GK G++ + + DQF+P S T+ R PL +
Sbjct: 2900 QGATLSASTTQAPAGKMFSLIGTNLVERFSDQFNPMLIGQDKAWSLTDSTIIRMPL--ST 2957
Query: 201 QASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEPKPKK---IH 257
+ + + IS F+ E L+FLKSV + W+ G +P + +H
Sbjct: 2958 EILKDGFEAGLDRVKQISDQFL---ENASRILIFLKSVSQVSFSTWEQGNAQPHQDYTLH 3014
Query: 258 SCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVRQVDRFYIVQT 317
S S++ + + L+ SK ++ + E + + +DR+ +V +
Sbjct: 3015 IDSASAIMRNPFAEKN--LKTSKLSRIFGSSNSGVKSRIIEVNLHIGENKLLDRWLVVLS 3072
Query: 318 MASASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTGQAFCFLPLPVRTGL 377
S S+ + K L P A +AA +S N DV LPL L
Sbjct: 3073 KGSGQSQNMA---RGRKYLAYNLTPVAGVAAHVSRNGRPVDVHAASPIMSPLPLSGSVNL 3129
Query: 378 SVQVNGFFEVSSNRRGIWYGD---------DMDRSGKVRSIWNRLLLEDLVAPAFVHML- 427
V + G F + +N + + +D + WN+ L+ V +++ ++
Sbjct: 3130 PVTILGCFLIRNNCGRFLFKNKNERAMSEPQLDAGDILIDAWNKELM-SCVRDSYIEIVV 3188
Query: 428 ----------------HGVKELLGPTDIY----YSLWPTGS----------FEEPWSILV 457
++L Y YS WP + + W LV
Sbjct: 3189 EMERLSREHSSSSTESSTARQLALSLKAYGHQLYSFWPRSNQHDDAIEAEVLKPEWECLV 3248
Query: 458 QQI----YINICNAPVIYSNLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQLGMPVVHLP 513
+Q+ Y + + P+ L G V E + ++ L L H P
Sbjct: 3249 EQVIRPFYARVADLPL--WQLYSGSLVKAEEGMFLTQPGSEVAVNLLPLTVCSFVKEHYP 3306
Query: 514 --NSLFDMLLKYNSSKV----ITPGTVRQFLRECESCNHLSRAHKLL-LLEYCLEDL 563
+ +++L + + + + P VR LR+ + L + +LEYCL D+
Sbjct: 3307 VFSVPWELLAEVQAVGIPVREVKPKMVRVLLRKSSASIDLRSVDTFIDVLEYCLSDI 3363
Score = 64.7 bits (156), Expect = 4e-08
Identities = 175/779 (22%), Positives = 285/779 (36%), Gaps = 141/779 (18%)
Query: 675 PTSSWFVLFWQYLGKQSEILPLFKDWPILPSTSG----------HLL---RPSRQLKMIN 721
P+ W LFW+ ++ L LF DWP++P+ G HL+ P+ Q +
Sbjct: 3562 PSPEWIQLFWKNFNGSADELSLFSDWPLIPAFLGRPILCRVRERHLIFFPPPALQPVSRS 3621
Query: 722 GSTLSDTVQDILVKI----GCHILKPGYVV-------EHPDLFSYL-------CGGNAAG 763
G+ + T DI L YV +HP L L C
Sbjct: 3622 GTDMHQTDSDISTTSVSGGPLSELTQRYVSGFDLAQSKHPWLILLLNQCNIPVCDTAYID 3681
Query: 764 VLE----------SIFNAFSS--AENMQVSFSSLIAE----ERNELRRFLLDPQWYVGHS 807
E S+ A +S AE + + + IA R+EL L + G S
Sbjct: 3682 CAERCKCLPSPSVSLGQAIASKLAEGKRAGYIADIASFPTFGRDELFTLLANDFSSSGSS 3741
Query: 808 MDEFNIRFCRRLPIYQVYHREPTQDSQFS-DLENPRKYLPPLDVPEFIL----VGIEFIV 862
+ + LPI++ T + + + +L P D F V F+
Sbjct: 3742 YQAYELEVLSSLPIFKTVTGSYTHLQRHGLCIISGDSFLKPYDECCFCYLPDSVECHFLQ 3801
Query: 863 RSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSIMLSVLQNLPLLSLE-D 921
T +L + + R G A+F + +R+ I++ V N L LE D
Sbjct: 3802 ALGVT---VLHNHQTLVRFGLAEFESR---------SQSEREDILIYVYGNW--LDLEVD 3847
Query: 922 ASIRDLLRNLKFIPT---VIGTLKCPSVLYDPRNEEIYALL-EDSDSFPSGVFRESETLD 977
+ + + LR KF+ L L+DP + + ++ + FP F L
Sbjct: 3848 SDVIEALREAKFVRNSDEFSSELSKSKDLFDPSDTLLVSVFFGERKRFPGERFSSEGWLR 3907
Query: 978 IMRGLGLKTSVSPDTVLESARCIEHLMHEDQQKAYLKGKVLFSYLEVNALKWLPDKFDDK 1037
I+R GL+T+ D +LE A+ +E L +E + + F V++ K + +
Sbjct: 3908 ILRKAGLRTAAEADVILECAKRVEFLGNERNRSSEEDD---FETDLVHSEKDISVELSTL 3964
Query: 1038 KGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPVLVSPPFHSL------------ 1085
G+V + F S F N L I+ P F SL
Sbjct: 3965 AGSVIEAILLNFAGFYST-------AFCNTLGQIACVPA--ESGFPSLGGRKGGKRVLTR 4015
Query: 1086 --------PWPVVSSMVAPPKVVR--PPNDLWLVSAGMRILDGECSSTALLYCLGWMCPP 1135
WP+ S V R PP W +R+ ST L + +
Sbjct: 4016 YSEAVLLRDWPLAWSSVPILSTQRFIPPGFSW---TALRLKSPPIFSTVLKHLQ--VIGR 4070
Query: 1136 GGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVK-AVLEGCR 1194
GG L + ++T V E+ + ++ LT SD +E+ K A L
Sbjct: 4071 NGG--EDTLAHWPNDPNVMTIDVTSCEVLKYLEIVWDSLTT---SDILELQKVAFLPAAN 4125
Query: 1195 WIWVGDGFATSDEVVLDGPLHLAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFR 1254
G + + + P++L+P+ +P F N+ +LG+ + L + +IL +
Sbjct: 4126 ----GTRLVGASSLFVRLPINLSPFAFELPSLYLPFLNILKDLGLNDVLSVAAAKDILSK 4181
Query: 1255 MANKKGSSPLDTQEIRAVMLIVHHLAEVY-------LHGQKVQLYLPDVSGRLFLAGDLV 1307
+ G L+ E+RAVM I+H L + ++ K + +PD RL A V
Sbjct: 4182 LQKLCGYRRLNPNELRAVMEILHFLCDEINTTKPPEINTIKSDVIVPDDGCRLVHALSCV 4241
Query: 1308 YNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAE 1366
Y D SFG+ + R + VH + + LGVR L +++ E
Sbjct: 4242 YVD------------SFGSRYVRYIDTARL--RLVHPLLPERICLDLGVRKLSDVVIEE 4286
Score = 41.6 bits (96), Expect = 0.33
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 4/46 (8%)
Query: 2072 WQHASLVSWTPGIHGQPSLEWLQLLWNYLKANCDDLLMFSKWPILP 2117
W+ S S G PS EW+QL W + D+L +FS WP++P
Sbjct: 3550 WESTSSSSDDSG----PSPEWIQLFWKNFNGSADELSLFSDWPLIP 3591
>ref|XP_474331.1| OSJNBa0018M05.18 [Oryza sativa (japonica cultivar-group)]
gi|38344927|emb|CAE03243.2| OSJNBa0018M05.18 [Oryza
sativa (japonica cultivar-group)]
Length = 4666
Score = 2721 bits (7052), Expect = 0.0
Identities = 1384/2355 (58%), Positives = 1738/2355 (73%), Gaps = 37/2355 (1%)
Query: 6 PESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGD 65
P + LEDFGQ VDLTRRIREVL NYPEGTT L+ELIQNADDAGA+ V LCLDRR+H
Sbjct: 3 PGGMLLEDFGQRVDLTRRIREVLANYPEGTTALRELIQNADDAGASRVRLCLDRRAHGAG 62
Query: 66 SLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLT 125
SLL+ +L+QWQGPALLAYNDAVFT++DF SIS+IG S K Q KTGRFGVGFNSVYHLT
Sbjct: 63 SLLAPALAQWQGPALLAYNDAVFTDEDFASISRIGDSRKVSQVWKTGRFGVGFNSVYHLT 122
Query: 126 DLPSFVSGKYVVLFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQS 185
DLPSFVSGKY+VLFDPQG YLP VSAANPGKRIDF SSA++LY DQ SPYCAFGCDM++
Sbjct: 123 DLPSFVSGKYIVLFDPQGAYLPNVSAANPGKRIDFVSSSAITLYNDQLSPYCAFGCDMKA 182
Query: 186 PFAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYV 245
PF GTLFRFPLR A+QAS S+LSRQ YT +DI S+F QL+EE V LLFLK+VL +EMYV
Sbjct: 183 PFQGTLFRFPLRTAEQASLSRLSRQVYTEDDILSLFAQLYEEAVYNLLFLKNVLSLEMYV 242
Query: 246 WDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTE--VDAFPLEFVTEAVRGV 303
W++G +PK ++SCS+ S D+ WHRQAL+R S + ++E +D+F ++FV+++ G
Sbjct: 243 WESGMSEPKIVYSCSIGSQHDNLRWHRQALVRFSGTAAESSEKKIDSFSMDFVSKSFLGE 302
Query: 304 ETVRQVDRFYIVQTMASASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTG 363
+ ++ ++IVQ MASA S+IG FA TA+K+YD+ LLPWAS+AACIS+
Sbjct: 303 KFEKKSYTYFIVQGMASALSKIGIFATTAAKDYDLHLLPWASVAACISN----------- 351
Query: 364 QAFCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAF 423
+ TGLSV VNG+FEVSSNRR IWYG DMDR GK+RS WN LLLED+VAP F
Sbjct: 352 -------VGPETGLSVHVNGYFEVSSNRRDIWYGADMDRGGKLRSDWNMLLLEDVVAPLF 404
Query: 424 VHMLHGVKELLGPTDIYYSLWPTGSFEEPWSILVQQIYINICNAPVIYSNLGGGRWVSPS 483
+L ++ +L YYSLWPTG +EEPWSILV+QI I +PV +S + GG W++P+
Sbjct: 405 RELLLQLRTVLDSKISYYSLWPTGLYEEPWSILVEQICKFIYTSPVFHSEIKGGTWITPA 464
Query: 484 EAFLHDEKFTKSKDLSLALMQLGMPVVHLPNSLFDMLLKYNSS---KVITPGTVRQFLRE 540
E+ LHDE F++S DLS AL+ LGMPVV LP ++ DM K++S K++TP TVR FL++
Sbjct: 465 ESLLHDEGFSRSDDLSEALVMLGMPVVRLPGAIADMFPKFHSKYMLKIVTPATVRHFLKD 524
Query: 541 CESCNHLSRAHKLLLLEYCLEDLVDDDVGKAAYNLPLLPLANGNFASFLEASKGIPYFIC 600
E+ L ++ KL+LLEYCL DL ++GK LPL+PLAN F F S+ Y++C
Sbjct: 525 FENLGTLEKSQKLILLEYCLADLDSGNIGKCMNGLPLIPLANKQFGIFSGISQENQYYVC 584
Query: 601 DELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSNTNIALFSIHHFAHLFPVFMPDDWK 660
D +EY+LL VSDR+ID+SIPP IL +L IA SS NI+L F FP P WK
Sbjct: 585 DSIEYELLSAVSDRIIDRSIPPVILDKLYQIASSSQVNISLIEGRIFLQFFPWLFPPGWK 644
Query: 661 YKCKVFWDPDSC-QKPTSSWFVLFWQYLGKQSEILPLFKDWPILPSTSGHLLRPSRQLKM 719
+ +V WDP+S PT++WF LFWQY+G S L LF DWPILPSTSGHL R S K+
Sbjct: 645 CRNQVPWDPESGGSSPTAAWFKLFWQYIGDCSYDLDLFSDWPILPSTSGHLYRASTVSKL 704
Query: 720 INGSTLSDTVQDILVKIGCHILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFS-SAENM 778
IN +LS+ ++++L K+GC IL Y+ L +Y+ G+A+GVL SIF S ++
Sbjct: 705 INTGSLSNLMKELLTKLGCKILDTKYLSTCQHLSNYVYDGDASGVLHSIFGVASLEGVDL 764
Query: 779 QVSFSSLIAEERNELRRFLLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDL 838
Q F + E+NEL +F+LD +WY+G + + +I C++LPI++V+ FSDL
Sbjct: 765 QALFQRITPAEKNELYQFVLDAKWYLGPHLSDMSINLCKKLPIFRVFDGGSPSSYGFSDL 824
Query: 839 ENPRKYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGEL 898
RKYLPPL V E +L +F+ S ++EDI+ RYYG+ERM K+ FY+++V +R+ EL
Sbjct: 825 STSRKYLPPLGVAEQLL-NDDFVFCISPSDEDIIMRYYGIERMPKSNFYQRYVLNRLDEL 883
Query: 899 QAEDRDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYAL 958
Q E RDS++L++LQ+LP LSLE+ ++ L+ L+F+PT G LK P LYDPR EE+YAL
Sbjct: 884 QTEFRDSVLLTILQDLPQLSLENPRFKEALKVLRFVPTTNGVLKSPQSLYDPRVEELYAL 943
Query: 959 LEDSDSFPSGVFRESETLDIMRGLGLKTSVSPDTVLESARCIEHLMHEDQQKAYLKGKVL 1018
L++SD FP G+F+ E LD++ LGL+TSVS DT+++SAR I+ L+H+D KA+ +GKVL
Sbjct: 944 LQESDCFPHGLFQNPEVLDMLLCLGLRTSVSIDTIIQSARHIDSLVHKDHHKAHSRGKVL 1003
Query: 1019 FSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNT--KSDIEKFWNDLQLISWCPV 1076
SYLEV+A KW K D + VN +L++ T RSR+T ++D+EKFW+DL++I WCPV
Sbjct: 1004 LSYLEVHAHKWYVHKPFDGRKKVN-MLAKVTTVLRSRDTSWEADLEKFWSDLRMICWCPV 1062
Query: 1077 LVSPPFHSLPWPVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLGWMCPPG 1136
LV+ P +LPWP VSSMVAPPK VR +D+W+VSA RILDGEC+S+AL Y LGW+ PP
Sbjct: 1063 LVTAPSPALPWPSVSSMVAPPKQVRMQDDMWIVSASSRILDGECTSSALSYSLGWLSPPS 1122
Query: 1137 GGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVKAVLEGCRWI 1196
G VIAAQLLELGKNNEIVTDQVLRQELAL MP+IYS+L+ +IGSDE++IVK VLEGCRWI
Sbjct: 1123 GSVIAAQLLELGKNNEIVTDQVLRQELALVMPKIYSLLSNLIGSDEMDIVKVVLEGCRWI 1182
Query: 1197 WVGDGFATSDEVVLDGPLHLAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFRMA 1256
WVGDGFA +DEVVL G LHLAPYIRVIP+DLAVFK+LFLELGI+E L P DY +IL RMA
Sbjct: 1183 WVGDGFAKTDEVVLTGHLHLAPYIRVIPIDLAVFKDLFLELGIKEQLDPVDYASILTRMA 1242
Query: 1257 NKKGSSPLDTQEIRAVMLIVHHLAEVYLHGQKVQLYLPDVSGRLFLAGDLVYNDAPWLLG 1316
+K S+ L +E+R +L+V HLAE + Q+YLPD S RL L+ +LV+NDAPWLL
Sbjct: 1243 TRKASTSLQAEELRTAVLVVQHLAEFRFQDHQTQIYLPDSSARLCLSSELVFNDAPWLLD 1302
Query: 1317 SEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAESADSMNFGLS 1376
++ GNAPS+ +N+K+ V FVHGNISNDVAE+LGVRSLRR+LLAES+DSMN LS
Sbjct: 1303 FDED--ITGNAPSIAFNSKKYVHNFVHGNISNDVAERLGVRSLRRLLLAESSDSMNLSLS 1360
Query: 1377 GAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLDKSQYGTSSVL 1436
G AEAFGQHE LTTRLKHI+EMYADGPG LFELVQNAEDA ASEV+FLLDK+ YGTSS+L
Sbjct: 1361 GVAEAFGQHEDLTTRLKHIVEMYADGPGILFELVQNAEDAKASEVVFLLDKTHYGTSSIL 1420
Query: 1437 SPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIP 1496
SPEMA+WQGPALYCFNDS+F+PQDLYAISRIGQ+SKLEK FAIGRFGLGFNCVYHFTDIP
Sbjct: 1421 SPEMAEWQGPALYCFNDSIFSPQDLYAISRIGQDSKLEKPFAIGRFGLGFNCVYHFTDIP 1480
Query: 1497 MFVSGENIVMFDPHASNLPGISPSHPGLRIKFAGRKILEQFPDQFSSLLHFGCDLQHPFP 1556
FVSGENIVMFDPHAS LPGISPSHPGLRIKF GR+ILEQFPDQF+ LHFGC+LQ PFP
Sbjct: 1481 GFVSGENIVMFDPHASYLPGISPSHPGLRIKFVGRRILEQFPDQFTPFLHFGCNLQQPFP 1540
Query: 1557 GTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISIFLKEG 1616
GTLFRFPLR ASRSQIK+E YTP+DV LF++FSEVVSE LLFLRNVK+I++++KE
Sbjct: 1541 GTLFRFPLRNEAAASRSQIKREQYTPQDVEMLFSSFSEVVSEALLFLRNVKNITLYVKES 1600
Query: 1617 TGHEMRLLHRVSRASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLSLSIDRDLPY 1676
EM+L+HRVS+ + E + + F ++ GM+R QF KL+ + D DLP+
Sbjct: 1601 DSQEMKLVHRVSKHNSYEMAKEPHALNTMLAFINGNQPSGMDRNQFFNKLNKTKDSDLPW 1660
Query: 1677 KCQKILITEQGTHGRNSHYWIMTECLGGGNVLKGTSEASTSNSHNFVPWACVAAYLNSVK 1736
QK+ I EQ H WI+TE +GG + K S AS S SH FVPWA VAAYL+SV
Sbjct: 1661 SSQKVSIFEQSPAACLVHSWILTESIGGXHARK-LSTASGSKSHFFVPWASVAAYLHSVT 1719
Query: 1737 --HGEDLVDSAEVEDDCLVSSDLFQFASLPMHPRENFEGRAFCFLPLPISTGLPAHVNAY 1794
+ ++L AEV D LV L +S R+ FEGRAFCFLPLPI+T +P HVNAY
Sbjct: 1720 VDNTKELSGEAEVNLDDLVLKQLSLGSS---KDRKFFEGRAFCFLPLPINTSMPVHVNAY 1776
Query: 1795 FELSSNRRDIWFGSDMTGGGRKRSDWNIYLLENVVAPAYGRLLEKVALEIGPCYLFFSLW 1854
FELSSNRRDIW G+DM GGGR RS+WN+ LLE+V APAYG LL +A E+GP LF S W
Sbjct: 1777 FELSSNRRDIWIGNDMAGGGRVRSEWNLALLEDVAAPAYGHLLAAIAQELGPSDLFLSFW 1836
Query: 1855 PKTLGLEPWASVIRKLYQFVAEFNLRVLYTEARGGQWISTKHAIFPDFSFPKADELIKAL 1914
P +G+EPW+S++RKLY +AE L VLYT+ARGG W+ST+ AIFPDFSF KA EL + L
Sbjct: 1837 PTAVGVEPWSSMVRKLYVSIAELGLHVLYTKARGGHWVSTRQAIFPDFSFSKAIELAEVL 1896
Query: 1915 SGASLPVITLPQSLLERFMEICPSLHFLKPKLLRTLLIRRKREFKDRDAMILTLEYCLHD 1974
S A LPV+++ + +++ F+ PS+H L P LLR LLIRRKR F++R+ IL LEYCL D
Sbjct: 1897 SEAGLPVVSVSKQIVDSFLNAYPSVHLLNPHLLRNLLIRRKRGFRNREEAILVLEYCLSD 1956
Query: 1975 FEESMQFDTLGGLPLLPLADGSFTSIEMKGIGERVYIARGDEYGLLRDSIPHQLVDCVIP 2034
+ D L GL LLPLA+GSFT+ +G GERV+ + E+ LL+DSIPH +VD +P
Sbjct: 1957 MGDPSFPDKLQGLALLPLANGSFTTFTNRGEGERVFFSSQMEFELLKDSIPHLVVDNSLP 2016
Query: 2035 KEVHRKLCYIAQTDSTNISFLSCQLLEKLLVKLLPVEWQHASLVSWTPGIHGQPSLEWLQ 2094
+ +KL IA + +NI +C L +LL ++LP EWQHA + W+PG GQPS+EW+
Sbjct: 2017 DAILKKLYDIACSARSNIYLFTCNFLLELLPRILPPEWQHAKQLFWSPGHQGQPSVEWMV 2076
Query: 2095 LLWNYLKANCDDLLMFSKWPILPVGDDCLIQLKPNLNVIKNDGWSEKMSSLLVKVGCLFL 2154
LWN+L+ +C+DL +F+KWPILP+ D L+QL NVI +DGWSE M SLL K+GC FL
Sbjct: 2077 SLWNFLRHSCEDLSIFAKWPILPLVDGKLMQLGNASNVIIDDGWSENMYSLLQKLGCFFL 2136
Query: 2155 RPDLQLDHPKLECFVQSPTARGVLNVFLAVAGEPQKIEGIFTDASDGELHELRSFILQSK 2214
R DLQ++HP+L FVQ TA GVLN +VA Q I+ +F S E HELRSFI QSK
Sbjct: 2137 RSDLQIEHPQLANFVQEATAVGVLNAVQSVASNFQDIKELFMGISLAETHELRSFIFQSK 2196
Query: 2215 WFSEEQIDRSHVETIKHLPMFESYKSRKLVSLIKPIKWLGPTGVGEDLLNDSFIRTESDM 2274
WFS ++ SH+ TI++LP+FESYKSR+LVSL P KWL P GV EDLLN+SFIRTES
Sbjct: 2197 WFSGNHMNSSHMNTIRNLPIFESYKSRELVSLTSPRKWLKPEGVHEDLLNESFIRTESAK 2256
Query: 2275 ERVIMRRYLEIKEPTRVEFYKDHIFNRMSEFLLKPEVVSSILNDVQLLIKEDISLKSSLS 2334
E+ I+ Y I+EP + EFYKDH+ R+SEFL +P VVS+IL DV+LL + D S++++L
Sbjct: 2257 EKSILVSYFAIREPQKAEFYKDHVLPRISEFLSQPAVVSAILRDVKLLAENDTSVRAALH 2316
Query: 2335 AVSFVLAADGSWQQP 2349
FVLAA G+W P
Sbjct: 2317 ETPFVLAASGAWVHP 2331
Score = 871 bits (2251), Expect = 0.0
Identities = 625/2103 (29%), Positives = 996/2103 (46%), Gaps = 241/2103 (11%)
Query: 12 EDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSS 71
E FGQ DLT R++ ++ Y +G +L EL+QNA+DA A+ V LD+ + S+LS
Sbjct: 1364 EAFGQHEDLTTRLKHIVEMYADGPGILFELVQNAEDAKASEVVFLLDKTHYGTSSILSPE 1423
Query: 72 LSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFV 131
+++WQGPAL +ND++F+ D +IS+IG SK + GRFG+GFN VYH TD+P FV
Sbjct: 1424 MAEWQGPALYCFNDSIFSPQDLYAISRIGQDSKLEKPFAIGRFGLGFNCVYHFTDIPGFV 1483
Query: 132 SGKYVVLFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTL 191
SG+ +V+FDP YLP +S ++PG RI F G L + DQF+P+ FGC++Q PF GTL
Sbjct: 1484 SGENIVMFDPHASYLPGISPSHPGLRIKFVGRRILEQFPDQFTPFLHFGCNLQQPFPGTL 1543
Query: 192 FRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEP 251
FRFPLRN ASRS++ R+ YTP+D+ +F E LLFL++V I +YV ++
Sbjct: 1544 FRFPLRNEAAASRSQIKREQYTPQDVEMLFSSFSEVVSEALLFLRNVKNITLYVKESDSQ 1603
Query: 252 KPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTE-----------AV 300
+ K +H S + S + AL + +N +F + +
Sbjct: 1604 EMKLVHRVSKHN-SYEMAKEPHALNTMLAFINGNQPSGMDRNQFFNKLNKTKDSDLPWSS 1662
Query: 301 RGVETVRQVDRFYIVQTMASASSRIGSFA---ITASKEYDIQLLPWASIAACISDNSLNN 357
+ V Q +V + S G A TAS +PWAS+AA + +++N
Sbjct: 1663 QKVSIFEQSPAACLVHSWILTESIGGXHARKLSTASGSKSHFFVPWASVAAYLHSVTVDN 1722
Query: 358 D--------------VLRT-------------GQAFCFLPLPVRTGLSVQVNGFFEVSSN 390
VL+ G+AFCFLPLP+ T + V VN +FE+SSN
Sbjct: 1723 TKELSGEAEVNLDDLVLKQLSLGSSKDRKFFEGRAFCFLPLPINTSMPVHVNAYFELSSN 1782
Query: 391 RRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHMLHGVKELLGPTDIYYSLWPTGSFE 450
RR IW G+DM G+VRS WN LLED+ APA+ H+L + + LGP+D++ S WPT
Sbjct: 1783 RRDIWIGNDMAGGGRVRSEWNLALLEDVAAPAYGHLLAAIAQELGPSDLFLSFWPTAVGV 1842
Query: 451 EPWSILVQQIYINICNAP--VIYSNLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQLGMP 508
EPWS +V+++Y++I V+Y+ GG WVS +A D F+K+ +L+ L + G+P
Sbjct: 1843 EPWSSMVRKLYVSIAELGLHVLYTKARGGHWVSTRQAIFPDFSFSKAIELAEVLSEAGLP 1902
Query: 509 VVHLPNSLFDMLLK-YNSSKVITPGTVRQFLRECESCNHLSRAHKLLLLEYCLEDLVDDD 567
VV + + D L Y S ++ P +R L + +R +L+LEYCL D+ D
Sbjct: 1903 VVSVSKQIVDSFLNAYPSVHLLNPHLLRNLLIRRKR-GFRNREEAILVLEYCLSDMGDPS 1961
Query: 568 VGKAAYNLPLLPLANGNFASFLEASKGIPYFICDELEYKLL-EPVSDRVIDQSIPPNILT 626
L LLPLANG+F +F +G F ++E++LL + + V+D S+P IL
Sbjct: 1962 FPDKLQGLALLPLANGSFTTFTNRGEGERVFFSSQMEFELLKDSIPHLVVDNSLPDAILK 2021
Query: 627 RLSGIAMSSNTNIALFSIHHFAHLFPVFMPDDWKYKCKVFWDPDSCQKPTSSWFVLFWQY 686
+L IA S+ +NI LF+ + L P +P +W++ ++FW P +P+ W V W +
Sbjct: 2022 KLYDIACSARSNIYLFTCNFLLELLPRILPPEWQHAKQLFWSPGHQGQPSVEWMVSLWNF 2081
Query: 687 LGKQSEILPLFKDWPILPSTSGHLLRPSRQLKMINGSTLSDTVQDILVKIGCHILKPGYV 746
L E L +F WPILP G L++ +I S+ + +L K+GC L+
Sbjct: 2082 LRHSCEDLSIFAKWPILPLVDGKLMQLGNASNVIIDDGWSENMYSLLQKLGCFFLRSDLQ 2141
Query: 747 VEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEERNELRRFLLDPQWYVGH 806
+EHP L +++ A GVL ++ + S+ ++++ F + E +ELR F+ +W+ G+
Sbjct: 2142 IEHPQLANFVQEATAVGVLNAVQSVASNFQDIKELFMGISLAETHELRSFIFQSKWFSGN 2201
Query: 807 SMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKYLPPLDVPEFILVGIEFIVRSSN 866
M+ ++ R LPI++ Y + + L +PRK+L P V E +L FI S
Sbjct: 2202 HMNSSHMNTIRNLPIFESY-----KSRELVSLTSPRKWLKPEGVHEDLL-NESFIRTESA 2255
Query: 867 TEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSIMLSVLQNLPLLSLEDASIRD 926
E+ IL Y+ + KA+FYK HV R+ E ++ +++ ++L+++ LL+ D S+R
Sbjct: 2256 KEKSILVSYFAIREPQKAEFYKDHVLPRISEFLSQP--AVVSAILRDVKLLAENDTSVRA 2313
Query: 927 LLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLEDSDSFPSGVFRESETLDIMRGLGLKT 986
L F+ G PS LYDPR E++ LL FPS F +E ++++ GLK+
Sbjct: 2314 ALHETPFVLAASGAWVHPSRLYDPRVPELHKLLHKETFFPSEKFMTTEVIELLASFGLKS 2373
Query: 987 SVSPDTVLESARCIEHLMHEDQQKAYLKGKVLFSYLEVNALKWLPDKFDDKK---GAVNR 1043
+ T+L+ AR + Q A GK L +YL N L++ +DKK G N+
Sbjct: 2374 KLGFSTLLDIARSVSL----QQDDALEHGKRLLTYL--NFLEFKASNMEDKKTFHGDDNQ 2427
Query: 1044 ILSQAATAFRSRNTKSDIE-------------------KFWNDLQLISWCPVLVSPPFHS 1084
S+ +F + N + +FW++L+ ISWCPV V+P
Sbjct: 2428 EASKTDGSFEAENDGDGYDPEETILSLFSNFDHDLPEDEFWSELKNISWCPVHVAPLLKG 2487
Query: 1085 LPWPVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLGWMCPPGGGVIAAQL 1144
LPW + VAPP RP + +WLVS+ MRIL + S L LGW+ PP ++++QL
Sbjct: 2488 LPWFISEDHVAPPITTRPKSQMWLVSSKMRILSADSCSMYLQRKLGWLDPPNANILSSQL 2547
Query: 1145 LELGK--------NNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVKAVLEGCRWI 1196
+E+ K + + D V ++E+ L IYS L +I + + I+K L+G W+
Sbjct: 2548 VEISKSYDELKMFSEDSTNDAVPQKEIQL----IYSKLQDIIDTADTNILKRNLDGHPWV 2603
Query: 1197 WVGDGFATSDEVVLDGPLHLAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFRMA 1256
++GD F + D P+ PY+ +P +L+ +K L LG+++ +DY+N+L +
Sbjct: 2604 YIGDRFVPPQALAFDSPVKYHPYLYAVPSELSEYKRLLSVLGVKQTFDAADYLNVLQCLQ 2663
Query: 1257 NKKGSSPLDTQEIRAVMLIVHHLAEVYLHGQKV-----QLYLPDVSGRLFLAGDLVYNDA 1311
+ PL T+++ V ++ + Y Q L +PD G L A +LVYNDA
Sbjct: 2664 SDAKGEPLSTEQLSFVHRVLEAFVDCYPDNQAPDMMVNSLLIPDSFGVLTPARNLVYNDA 2723
Query: 1312 PWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAESADSM 1371
PW+ NA T + FVH +I ND+A +LGVRSLR L + D +
Sbjct: 2724 PWM------------------NADPTSKSFVHLSIGNDLANRLGVRSLRGSSLLD--DEL 2763
Query: 1372 NFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLDKSQYG 1431
L A ++ +L +Y + LF+L++ A+ A +V + DK +
Sbjct: 2764 MTDLPCMEYA---------KISELLALYGESDFLLFDLIELADHCNAKKVHLIYDKRDHP 2814
Query: 1432 TSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYH 1491
S+L + D+QG +L + ++ ++ KL+ I +GLG Y
Sbjct: 2815 KQSLLQQSLGDFQGSSLTVVFEGTIMSREEVCSLQLPPPWKLKG--NILNYGLGLLSSYF 2872
Query: 1492 FTDIPMFVSGENIVMFDPHASNLPGISPSHPGLRIKF---AGRKILEQFPDQFSSLLHFG 1548
D +SG +FDP L G + S +F G ++E+F DQF+ +
Sbjct: 2873 VCDTLSILSGGYFYIFDP--LGLTGGTTSIATSSARFFSLIGNDLVERFHDQFTPMRVTQ 2930
Query: 1549 CDLQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKS 1608
T+ R PL S +K+ V+ +F F++ S TLLFLR++
Sbjct: 2931 EASLSSANSTVIRMPL------SSKCLKELEAGCNRVKHIFDRFTQNPSSTLLFLRSIIQ 2984
Query: 1609 ISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLSL 1668
+S+ EG S+ +L S + V + N F E + R L ++
Sbjct: 2985 VSLSTWEG---------GASQPTLNYSVLVDPSVATLRNPFSEKKW----RKFQLSRIFA 3031
Query: 1669 SIDRDLPYKCQKILITEQGTHGRNSHYWIMTECLGGGNVLKGTSEASTSNSHNFVPWACV 1728
S + + + + + G + + W + CLG G + + ++N P A V
Sbjct: 3032 STSAAIKMQAIDVHVIDNGCNYIDK--WFVALCLGSGQT-RNMALDRRYLAYNLTPVAGV 3088
Query: 1729 AAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMHPRENFEGRAFCFLPLPISTGLP 1788
AA++ ++G V + C++S LPL S +P
Sbjct: 3089 AAHI--ARNG---VSTNIHASSCILSP-----------------------LPLSGSISMP 3120
Query: 1789 AHVNAYFELSSNRRDIWFG-------SDMTGGGRKRSD-WNIYLLENVVAPAYGRLLEKV 1840
+F + N FG SD+ K + WN L+ V +LE
Sbjct: 3121 VTTLGHFIVRHNGGRYIFGSSHDKSLSDLEMHKNKLVEAWNKELMLCVRDSYVEMVLEFQ 3180
Query: 1841 ALEIGPCY--------------------LFFSLWPKT----LGLEPWASVIRKL------ 1870
L P +S WP++ L + S + +
Sbjct: 3181 KLRKDPLSSAIESRSAHSVSTILQAYGDRVYSFWPRSKQHPASLTGYGSTVTNVNSPRAS 3240
Query: 1871 ---YQFVAEFNLRVLYT--------EARGGQWISTKHAIFPDFSFPKADELIKALSGASL 1919
+Q + E +R Y + GG + +F S D+ + + S S
Sbjct: 3241 KADWQSLVEQVIRPFYVRLADLPVWQLYGGNLVKVDVGMFLSHSGSGDDDNLPSASVCSF 3300
Query: 1920 -----PVITLPQSLLERFMEICPSLHFLKPKLLRTLL-IRRKREFKDRDAMILTLEYCLH 1973
PV ++P L+ + ++ ++PK++R LL + + + LEYC
Sbjct: 3301 IKEHYPVFSVPWELVREIQAVGVNVREIRPKMVRDLLKASSSILLRSIETYMDVLEYCFS 3360
Query: 1974 DFE 1976
D +
Sbjct: 3361 DMD 3363
>emb|CAG02848.1| unnamed protein product [Tetraodon nigroviridis]
Length = 4658
Score = 462 bits (1188), Expect = e-128
Identities = 482/1691 (28%), Positives = 757/1691 (44%), Gaps = 205/1691 (12%)
Query: 14 FGQTVD-LTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
FGQT L ++++L YPEG +LKELIQNA+DAGAT V D H +SL S L
Sbjct: 185 FGQTTPPLVEFLKDILRRYPEGGQILKELIQNAEDAGATEVKFMYDETEHGVESLWSPDL 244
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
Q QG AL AYNDAVFT +D+ I +I S K K GRFG+GFNSVYH+TD+PS S
Sbjct: 245 EQHQGTALYAYNDAVFTLEDWSGIQEIARSRKRDDPLKVGRFGIGFNSVYHVTDVPSIFS 304
Query: 133 GKYVVLFDP-QGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCA-FGCD----MQSP 186
G + + DP Q ++ P S + D + LS DQF+PY FG +
Sbjct: 305 GDQIAMLDPHQTLFGPHESGQCWNLKTDTKEIAELS---DQFAPYFGIFGISEKHMKDAS 361
Query: 187 FAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVW 246
F GTLFRFPLR S+LS Y E + +F + LLFLKSV I ++V
Sbjct: 362 FPGTLFRFPLR----LRPSQLSSNVYNKEKVLELFESFKADADTVLLFLKSVNRISLHVR 417
Query: 247 DAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSL--------NTTTEVDAFPLEFVTE 298
++ + + + + S ++D + AL L +++ ++T + L T+
Sbjct: 418 ES-DGTERMLFQVTASGNAEDELERPNALKTLGQAVDGYSNGVPSSTVTCVTYQLNVDTQ 476
Query: 299 AVRGVETVRQVDRFYIVQTMASASSRIGSFAITASKEY---DIQLLPWASIAACISDNSL 355
ET R T S+ +G + A + D++ P IA ++
Sbjct: 477 DGAAKETQR---------TAWLVSNGVGGRGLCAELDALADDLKFTPTIGIALPLAVTGK 527
Query: 356 NNDVLR---TGQAFCFLPLP----VRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRS 408
+ +G+AFCFLPLP +TGL V V+GFF ++ NRR I + ++D+ +
Sbjct: 528 DEQGATSGFSGRAFCFLPLPPGEESQTGLPVHVSGFFGLTDNRRSIKW-REVDQWRDPAA 586
Query: 409 IWNRLLLEDLVAPAFVHML-HGVKEL---------LGPTDIYYSLWPT-GSFEEPWSILV 457
+WN+LLL ++ A++ ++ ++ + L P Y WP G W ++
Sbjct: 587 VWNQLLLVTVIPRAYLVLITEAIQRVQRRKDQDFPLSPMGT-YGAWPNPGQVRSRWKPIL 645
Query: 458 QQIYINICNAPVIYSNLGGGRWVSPSEAFLH--DEKFTKSKDLSLALMQLGMPVVHLPNS 515
Q ++ + PVI+S WV +A D S+ + L + G+ V +P S
Sbjct: 646 QPLFQELLRQPVIFSLCES--WVQADQAVFSELDPDQDTSEAVIAYLQKSGVQVAQVPAS 703
Query: 516 LFDMLLKYNSS-KVITPGTVRQFLRECESCNHLSRAHKLLLLEYCLEDLVDDDVGKAAYN 574
+ +L Y + K +TP +RQ +R S + S KL LLE+ L D D+
Sbjct: 704 VDAVLATYMTEVKKVTPSLLRQAMR--RSKHKGSSQEKLSLLEFVLADANYSDL----IG 757
Query: 575 LPLLPLANGNFASFLEASKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMS 634
L LLPL + FASF P +C L+ K + + +SI P++ L A S
Sbjct: 758 LELLPLQDETFASFAS-----PVSVC-ILDLKRV------FVLESIKPSVKDGLMKAAKS 805
Query: 635 SN---TNIALFSIHHFAHLFPVFMPDDWKYK-CKVFWDPDS--CQKPTSSWFVLFWQYLG 688
T + + S A L + W + V W+P + + PT SW + W++L
Sbjct: 806 RGRPCTQLQVLSPERSARLIKDVLSSAWPTRDFAVEWEPGNRELRHPTLSWLRMVWKHLY 865
Query: 689 KQ-SEILPLFKDWPILP-------STSGHLLRPSRQLKMI----NGSTLSDTVQDILVKI 736
+E L F+D P++P T HLLR +I + S + DI+ K+
Sbjct: 866 IHFAEDLSTFEDMPLIPLVPLEENMTRVHLLRLRTPSPIIFADAEEAAPSGNLLDIMEKL 925
Query: 737 GCHIL-KPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEERNELRR 795
G ++ K ++HP L +Y+ + A +L+ + S + + SS E+ LR+
Sbjct: 926 GGTVMTKLDSCLQHPLLKNYIHPSSPAALLQIMDRL--SKQRLASQVSSFSLTEKIALRK 983
Query: 796 FLLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKYLPPLDVPEFIL 855
+L + E L +++ S+F+ L R P +
Sbjct: 984 YLAGLS-----DVTEREKHTLLELSVFEKVGSSCEGSSRFTSLRGARALHHRAKYPPDVK 1038
Query: 856 VGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFD-RVGELQAEDRDSIMLSVLQNL 914
+ I +V + E L + +E++ + K V D G E+ IML LQ++
Sbjct: 1039 LSIN-LVGYCDEESIRLIKMLNIEQLTTTECLKFIVHDIERGFYTTEEMAHIMLWALQHM 1097
Query: 915 PLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYAL--LEDSDSFPSGVFRE 972
L E+ S+ L +KFI G L S L+DP E + L +E+ FP+
Sbjct: 1098 AFLKNENPSVLSWLSPIKFIQLPCGRLVKASDLFDPELEILQNLFYMEEKSRFPTSELAS 1157
Query: 973 S-ETLDIMRGLGLKTSV--SPDTVLESARCIEHLMHEDQQKAYLKGKVLFSYLEVNALKW 1029
S + L +R LGL+ V S V+ A+ IE L K L K
Sbjct: 1158 SPDVLHSLRQLGLRNEVQLSERDVVTVAKRIEELQRSQDAKEDLVIK------------- 1204
Query: 1030 LPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPVLVSPPFHSLPWPV 1089
K + +IL++ +S + +S + K + W PV P L +P
Sbjct: 1205 -------KAKTLLQILNRQTKLVKSADAQSALLK-------LQWVPVCKERP---LTYPK 1247
Query: 1090 VSSMVAPPKVVRPPNDL----WLVSAGMRILDGECSSTALLYCLGWMCPPGGGVIAAQL- 1144
S V + +++ V G + E +S + L P + L
Sbjct: 1248 SLSWVGDVATICSLSEMCDIAHAVLVGSAVALVEHTSAGMRKALKLNVEPQVDQVIQHLK 1307
Query: 1145 --LELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVKAVLEGCRWIWVGDGF 1202
+E K+ T+ + + L +Y + + D E +K++ W+W G F
Sbjct: 1308 AVIEWHKSQAFTTEDWYQFQQILF--EMYGFMQTHL-QDAKEAMKSL--PFDWVWTGKTF 1362
Query: 1203 ATSDEVVLD--GPLHLAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFRMANKKG 1260
++ D VL L L PY+ +P + F LF G E + PS + ++ + +
Sbjct: 1363 SSPDRTVLKPLPDLDLQPYLYSLPKTIRKFNKLFKSCGSIEEVDPSQVLEVVNTIQQRCT 1422
Query: 1261 SSPLDTQEIRAVMLIVHHLAEVYLHGQKV--QLYLPDV----SGRLFLAG-------DLV 1307
++L+++ L +Y + V +++P + RL + D+
Sbjct: 1423 GEMTKDDSKHNILLLINILRWLYNNQIPVATDMHVPILFHKDPSRLAMRPIHECTYCDIK 1482
Query: 1308 YNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAES 1367
+D LL ED + P V VH +I AE L V L L+ +
Sbjct: 1483 VDDLIDLL--EDT-----SEPIV----------LVHDDIPMRTAEWLKVPCLSTRLV--N 1523
Query: 1368 ADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLD- 1426
+++ F E GQ E LT R+K+ILE Y EL+QNA+DA A+E FL+D
Sbjct: 1524 PENLGF------EQSGQREPLTVRIKNILEEYPSVADIFKELLQNADDASATECNFLIDM 1577
Query: 1427 -KSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLG 1485
K+ ++L P M GP+L+ FN++VF+ D I+R+G K +A +G+FGLG
Sbjct: 1578 RKNNDIRENLLDPGMIACHGPSLWSFNNAVFSDTDFLNITRLGGSVKRSEADKVGKFGLG 1637
Query: 1486 FNCVYHFTDIPMFVSGENIVMFDPHASNLPG--ISPSHPGLRIKFA-GRKILEQFPDQFS 1542
FN VYH TDIP+ +S E +++FDP+ +++ S+PG++I ++ +K L +FP+QF
Sbjct: 1638 FNSVYHITDIPIIMSREFMIIFDPNINHISKHIRDRSNPGIKINWSKQQKRLRKFPNQFK 1697
Query: 1543 SLLH-FGC------DLQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEV 1595
++ FGC D + F GTLFR P RT AS+S+I Y D+ SL FS
Sbjct: 1698 PFINVFGCQLPLAQDSPYKFNGTLFRLPFRTEQEASQSEISSLYYNTTDIYSLVDEFSIC 1757
Query: 1596 VSETLLFLRNV 1606
+LF ++V
Sbjct: 1758 GHRFILFTQHV 1768
Score = 272 bits (696), Expect = 9e-71
Identities = 347/1478 (23%), Positives = 579/1478 (38%), Gaps = 249/1478 (16%)
Query: 13 DFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
+FGQ LT RI+ +L YP +LKEL+QNADDA AT + D R+H D +
Sbjct: 2600 EFGQKETLTSRIKSILSAYPSEKEMLKELLQNADDAKATEIYFIYDPRTHPTDRVFDDKW 2659
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
QGPAL YN+ FTEDD I +G +K KTG++G+GFNSVYH+TD PSF+S
Sbjct: 2660 IPMQGPALCVYNNQPFTEDDVRGIQNLGRGTKEANPGKTGQYGIGFNSVYHITDCPSFIS 2719
Query: 133 GKYVV-LFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTL 191
++ +FDP Y P ++A+PG+ S S + D + Y ++ T+
Sbjct: 2720 NNDILCIFDPHAQYAPGATSASPGRMFRDIDSDFRSQFSDVLNLYLGANFKLER---STM 2776
Query: 192 FRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEP 251
FRFP+R+ + A S++S + + ++ +L +G L+FL + I + D
Sbjct: 2777 FRFPIRSTEMAKTSEISSVPASDRMVQNLLDKLKSDGAELLMFLNHMEKISICEIDQSSG 2836
Query: 252 KPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVRQVDR 311
+P+ I+S + D + +Q + S+ + A P++ +T ++ ++T
Sbjct: 2837 QPRVIYSVTARISDGDRLKRKQFHASVIDSVMKKKPLSAIPVQQITYSMDILDTDGNSTT 2896
Query: 312 FYIVQTMASAS-SRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTGQAFCFLP 370
+ I + + ++A K DI L P +AAC+S N + +AFCFLP
Sbjct: 2897 WMICNRSGFPNIENVSKALVSAHKNEDITLFPRGGVAACVSHN-----YKKPHRAFCFLP 2951
Query: 371 LPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHML--- 427
L + TGL VNG F + S RR +W D+ VRS WN L+ L+APA V +L
Sbjct: 2952 LSLETGLPFHVNGHFALDSARRNLWRDDN---GVGVRSDWNTNLMTLLIAPACVELLIQL 3008
Query: 428 --------------------HGVKELLGPTDIYYSLWPTG--SFEEPWSILVQQIY---- 461
H VK+ L Y +P + W LV+ +Y
Sbjct: 3009 KRRYFPGPDPTMTILQGTPLHAVKDTLRK---YLFFFPANRLDIQPDWYCLVKAVYHCVH 3065
Query: 462 ----------------------------INICNAP---VIYSNLGGGRWVSPSEAFLHDE 490
+N C A + NL + L +
Sbjct: 3066 ADLKRLLPVLRAAPSDNSDMHSVIYILWVNTCTANKGRAFFDNL-----LQDELQHLKNT 3120
Query: 491 KFTKSKDLSLA---------LMQLGMPVVHLPNSLFDMLLKYNSSKV----ITPGTVRQF 537
++ + S+A L+ +G +++ + ++ ++ + +TP VR F
Sbjct: 3121 EYNVTSRKSVAENVYRLKTLLLDVGFNLIYSCDETANLYACLEAAGIPVSYVTPRDVRNF 3180
Query: 538 LRECES-----------C----NHLSRAHKL-LLLEYCLEDLVDDDVGKAAYNLPLLPLA 581
L S C +H H L LL++YC +D+ D+V LPLL +
Sbjct: 3181 LYTFSSPDTTCHVGKLPCRIQHSHYKLLHNLKLLVDYCFKDMEVDEV--KLEGLPLL-IT 3237
Query: 582 NGNFASFLEASKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSNTNIAL 641
N ++ + F+ + ++L+ D I+ + R S I M
Sbjct: 3238 MDNMLQVFDSKR--QKFLT--VHHELVSSRKDMFIN-----TLFMRYSSILMKQGI-AKH 3287
Query: 642 FSIHHFAHLFPVFMPDDWKYKCKVFWDPDSCQKPTSSWFVLFWQYL-------GKQSEIL 694
F I F L +P +++ K V W + SW W ++ G Q E
Sbjct: 3288 FDISSFGDLLGSVLPREYRTKVPVKWRDTFASE---SWLKNVWNFISENVAAKGDQLEHT 3344
Query: 695 PLF-------KDWPILPSTS------------GHLLRPSRQLKMINGSTLSDTVQDILVK 735
P F KDW +LP T LL S I +D V L+K
Sbjct: 3345 PGFDTAMDILKDWALLPGTKFLAKEKIVVPEHDVLLPLSLMHLAIFPQGQNDKVFHTLMK 3404
Query: 736 IGCHILKPGYV-VEHPDLFSYLCGG-----NAAGVLESI-----FNAFSSAENMQVSFSS 784
GC L + V+ + L N +L ++ +AF +A F +
Sbjct: 3405 SGCIQLAVNKISVKENPIMPILAQHTANIENPQSILRAVEYMIQASAFKAASLSDRDFEA 3464
Query: 785 LIAEERNELRRFLLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKY 844
L++ L S+ + N + + LP ++ + + + +
Sbjct: 3465 LLSYFSCNLA------------SLTQQNAQSLKLLPCFRSVGGKFMSIANYGASYVLVRN 3512
Query: 845 LPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRD 904
+P D+ ++ G + +++ S + G + + Y HV + + +
Sbjct: 3513 IPTADMDKWAHNGSSAFLADCPQLKELYS-FLGCAPIDDLEVYLHHVLPKFESFCYDAKV 3571
Query: 905 SIMLSVLQNLPLLSLEDAS-----IRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALL 959
+ + + L +S+E+ S + + L L FI L+ +D +L
Sbjct: 3572 EHVAYLKERL--VSMEEPSDFTDQLYEKLEGLMFIFDCSNRLRPAKFFFDETVRVFQVML 3629
Query: 960 EDSDSFPSGVFRESETLD---------------IMRGLGLKTSVSPDTVLESARCIEHLM 1004
S F++ E + +R +GLK VS VL+ A+ +
Sbjct: 3630 PAKSFITSDFFKKVEQVSRPKNGIASSLASWITFLRHIGLKHQVSQQQVLQFAK---EVS 3686
Query: 1005 HEDQQKAYLKGKVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTK------ 1058
+ Q + + K KV + ++V ++ D +G+ + LS + R K
Sbjct: 3687 IKAQTEGWTKEKVQTA-VDVLLSHVFNERTDLFQGSFLKELSMVQFLYPERAPKELVKLH 3745
Query: 1059 SDIEKFWNDLQLISWCPVLVSPPFHS-----LPW---PVVSSMVAPPKVVRPPNDLWLVS 1110
S ++ L LI + V+P F L W PV+ A P +R + L
Sbjct: 3746 SQYQEVSGSLPLIRFSGSQVNPKFKQTDAIHLLWTSCPVLPEQ-ATPSSIREQDGTSL-- 3802
Query: 1111 AGMRILDGECSSTALLYCLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRI 1170
G +L +L+ LG P + + + + + V + L
Sbjct: 3803 RGQELLH------QVLHLLGVNLDPPLEKVISNCKNICNISSPDDEMVKTRNKVLRST-- 3854
Query: 1171 YSILTGMIGSDEIEIVKAVLEGCRWIWVGDGFAT--SDEVV--LDGPLHLAPYIRVIPVD 1226
Y L G + + L G ++ V DG+ S+EVV LD PY+ +P++
Sbjct: 3855 YEFLNG-----DKRDFRYHLRGVAFVIVEDGWKLLKSEEVVINLDNESDFKPYLYKLPLE 3909
Query: 1227 LAVFKNLFLELGIREFLQPSDYVNILFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYLHG 1286
L F LF LG + + Y +L+R+ LD E+R V +V + LH
Sbjct: 3910 LGTFHQLFKLLGTEDVVSTKQYTEVLWRIYKNSEGKQLDPNEMRTVKRVVSGFFKS-LHN 3968
Query: 1287 QKVQL------------YLPDVSGRLFLAGDLVYNDAP 1312
V++ YLP G+L + LV++DAP
Sbjct: 3969 DPVEIRKDLENLRDLTFYLPSHDGKLAKSSSLVFDDAP 4006
Score = 238 bits (607), Expect = 2e-60
Identities = 241/866 (27%), Positives = 367/866 (41%), Gaps = 145/866 (16%)
Query: 1374 GLSGAAEAFGQHEA-LTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLDKSQYGT 1432
GL G FGQ L LK IL Y +G L EL+QNAEDAGA+EV F+ D++++G
Sbjct: 178 GLRGGGR-FGQTTPPLVEFLKDILRRYPEGGQILKELIQNAEDAGATEVKFMYDETEHGV 236
Query: 1433 SSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHF 1492
S+ SP++ QG ALY +ND+VFT +D I I + K + +GRFG+GFN VYH
Sbjct: 237 ESLWSPDLEQHQGTALYAYNDAVFTLEDWSGIQEIARSRKRDDPLKVGRFGIGFNSVYHV 296
Query: 1493 TDIPMFVSGENIVMFDPHASNLPGISPSHPGLRIKFAGRKILEQFPDQFSSLLH-FGCDL 1551
TD+P SG+ I M DPH L G S +K ++I E DQF+ FG
Sbjct: 297 TDVPSIFSGDQIAMLDPH-QTLFGPHESGQCWNLKTDTKEIAE-LSDQFAPYFGIFGISE 354
Query: 1552 QH----PFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVK 1607
+H FPGTLFRFPLR SQ+ VY E V LF +F LLFL++V
Sbjct: 355 KHMKDASFPGTLFRFPLR----LRPSQLSSNVYNKEKVLELFESFKADADTVLLFLKSVN 410
Query: 1608 SISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLS 1667
IS+ ++E G E R+L +V+ + E E + R LK L
Sbjct: 411 RISLHVRESDGTE-RMLFQVTASGNAEDE--------------------LERPNALKTLG 449
Query: 1668 LSID---RDLPYKC------QKILITEQGTHGRNSH-YWIMTECLGGGNVLKGTSEASTS 1717
++D +P Q + T+ G W+++ +GG + + +
Sbjct: 450 QAVDGYSNGVPSSTVTCVTYQLNVDTQDGAAKETQRTAWLVSNGVGGRGLCAELD--ALA 507
Query: 1718 NSHNFVPWACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMHPRENFEGRAFC 1777
+ F P +A L E S F GRAFC
Sbjct: 508 DDLKFTPTIGIALPLAVTGKDEQGATS-------------------------GFSGRAFC 542
Query: 1778 FLPLP----ISTGLPAHVNAYFELSSNRRDI-WFGSDMTGGGRKRSDWNIYLLENVVAPA 1832
FLPLP TGLP HV+ +F L+ NRR I W D + WN LL V+ A
Sbjct: 543 FLPLPPGEESQTGLPVHVSGFFGLTDNRRSIKWREVDQWRD--PAAVWNQLLLVTVIPRA 600
Query: 1833 YGRLLEKVA----------LEIGPCYLFFSLWPKTLGLEP-WASVIRKLYQFVAEFNLRV 1881
Y L+ + + P + WP + W +++ L+Q + LR
Sbjct: 601 YLVLITEAIQRVQRRKDQDFPLSPMGT-YGAWPNPGQVRSRWKPILQPLFQEL----LRQ 655
Query: 1882 LYTEARGGQWISTKHAIFPDFSFPK--ADELIKALSGASLPVITLPQSLLERFMEICPSL 1939
+ W+ A+F + + ++ +I L + + V +P S+ +
Sbjct: 656 PVIFSLCESWVQADQAVFSELDPDQDTSEAVIAYLQKSGVQVAQVPASVDAVLATYMTEV 715
Query: 1940 HFLKPKLLRTLLIRRKREFKDRDAMILTLEYCLHDFEESMQFDTLGGLPLLPLADGSFTS 1999
+ P LLR + R K + ++ + L LE+ L D + L GL LLPL D +F S
Sbjct: 716 KKVTPSLLRQAMRRSKHKGSSQEKLSL-LEFVLAD----ANYSDLIGLELLPLQDETFAS 770
Query: 2000 ---------IEMKGIGERVYIARGDEYGLLRDSIPHQLVDCVIPKEVHRKLCYIAQTDST 2050
+++K RV++ ++ S+ L+ K T
Sbjct: 771 FASPVSVCILDLK----RVFVLES-----IKPSVKDGLM----------KAAKSRGRPCT 811
Query: 2051 NISFLSCQLLEKLLVKLLPVEWQHASL-VSWTPGIH--GQPSLEWLQLLWNYLKAN-CDD 2106
+ LS + +L+ +L W V W PG P+L WL+++W +L + +D
Sbjct: 812 QLQVLSPERSARLIKDVLSSAWPTRDFAVEWEPGNRELRHPTLSWLRMVWKHLYIHFAED 871
Query: 2107 LLMFSKWPILP-------VGDDCLIQLKPNLNVIKNDGWSEKMSSLLVKV-----GCLFL 2154
L F P++P + L++L+ +I D S L+ + G +
Sbjct: 872 LSTFEDMPLIPLVPLEENMTRVHLLRLRTPSPIIFADAEEAAPSGNLLDIMEKLGGTVMT 931
Query: 2155 RPDLQLDHPKLECFVQSPTARGVLNV 2180
+ D L HP L+ ++ + +L +
Sbjct: 932 KLDSCLQHPLLKNYIHPSSPAALLQI 957
Score = 225 bits (574), Expect = 1e-56
Identities = 262/1029 (25%), Positives = 421/1029 (40%), Gaps = 169/1029 (16%)
Query: 848 LDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSIM 907
+++P+++ G E + E+ L+ + QF+ + F + E+ E RD ++
Sbjct: 2107 VELPDWVKEGFEDAGCKAKLLENTLT---------EKQFFAEVFFPHIQEIDKEHRDPLI 2157
Query: 908 LSVLQNLPLLSLEDASIRDLLRNLKFIPTV--IGTLKCPSVLYDPRNEEIYALLEDSDSF 965
VL LE+ S +LR +P TL PS L P D F
Sbjct: 2158 HYVLNE----KLEEFS--SILRVTPCVPCCGPRNTLVLPSRLIHPEGRVAKLYNTDDGRF 2211
Query: 966 PSGVFRE---SETLDIMRGLGL-KTSVSPDTVLESARCIEHLMHEDQQKAYLKGKVLFSY 1021
P G ++ L + LG+ K +S + ++E A + L D A + +L S
Sbjct: 2212 PKGTSKDYLNPVCLVKLVQLGMVKDDLSWEDLIERAESVVELNENDHMAACFRSSLLLSL 2271
Query: 1022 LEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPVLVSPP 1081
D+K A R + +E+ LQ I + P L P
Sbjct: 2272 T------------DEKLKA------------RDPGAEESLER----LQDIKFLPFLTRPA 2303
Query: 1082 FHSLPWPVVSSMVAPPKVVRPPNDLWLVSAG-----MRILDGECS---------STALLY 1127
SLPW P + +L+ M+ + E S S A+
Sbjct: 2304 GFSLPW---HGNNFSPATLFSARELFTSEHQDTVCLMKPILNENSPSFRGCGTVSLAVKD 2360
Query: 1128 CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEI--EI 1185
LG + P ++ +QL +L ++ + VT + ++ + A Y L + DE +
Sbjct: 2361 GLGLIRTPSVELVISQLKKLSQSFDGVT--LYQENITNAC---YKFLHEEMLQDERAKQQ 2415
Query: 1186 VKAVLEGCRWIWVGDGFATSDEVVLDGPLHLAPYIRVIPVDLA-VFKNLFLELGIREFLQ 1244
+ L I V + + + ++ +P++ +P + LF +G++
Sbjct: 2416 MAEELTAFNSILVENTYVSPAKIAFHLNFDASPHLYQLPNKYRNSCRELFESVGVKSSFS 2475
Query: 1245 PSDYVNILFRMANKKGSSPLDTQEIR--------AVMLIVHHLAEVYLHGQKVQLYLPDV 1296
D+ IL + G L + + ++ ++ + + LPD
Sbjct: 2476 VEDFSGILETVKQGCGRRALSEDNFQLCRRVISEGIWSLIRDKSQEHCKEHHSGILLPDS 2535
Query: 1297 SGRLFLAGDLVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGV 1356
+ L + L YND PW+ + T K+ HG+I +VA KLG
Sbjct: 2536 NLTLQPSKSLCYNDCPWI------------------KVRDTTVKYCHGDIPREVAVKLGA 2577
Query: 1357 RSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDA 1416
R L A ++ F G+ FGQ E LT+R+K IL Y L EL+QNA+DA
Sbjct: 2578 VPKRHKALERYASNICFTPPGSE--FGQKETLTSRIKSILSAYPSEKEMLKELLQNADDA 2635
Query: 1417 GASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKA 1476
A+E+ F+ D + T V + QGPAL +N+ FT D+ I +G+ +K
Sbjct: 2636 KATEIYFIYDPRTHPTDRVFDDKWIPMQGPALCVYNNQPFTEDDVRGIQNLGRGTKEANP 2695
Query: 1477 FAIGRFGLGFNCVYHFTDIPMFVSGENIV-MFDPHASNLPGISPSHPGLRIKFAGRKILE 1535
G++G+GFN VYH TD P F+S +I+ +FDPHA PG + + PG +
Sbjct: 2696 GKTGQYGIGFNSVYHITDCPSFISNNDILCIFDPHAQYAPGATSASPGRMFRDIDSDFRS 2755
Query: 1536 QFPDQFSSLLHFGCDLQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEV 1595
QF D + L L+ T+FRFP+R+ +A S+I + V++L
Sbjct: 2756 QFSDVLNLYLGANFKLER---STMFRFPIRSTEMAKTSEISSVPASDRMVQNLLDKLKSD 2812
Query: 1596 VSETLLFLRNVKSISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFNFFKEDRLV 1655
+E L+FL +++ ISI + + + R+++ V +A + D DRL
Sbjct: 2813 GAELLMFLNHMEKISICEIDQSSGQPRVIYSV-----------TARISD------GDRL- 2854
Query: 1656 GMNRAQFLKKLSLSIDRDLPYKC---QKILITEQ--GTHGRNSHYWIMTECLGGGNVLKG 1710
R QF + S+ + P Q+I + T G NS W++ G N+
Sbjct: 2855 --KRKQFHASVIDSVMKKKPLSAIPVQQITYSMDILDTDG-NSTTWMICNRSGFPNI--- 2908
Query: 1711 TSEASTSNSHNFVPWACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMHPREN 1770
V A V+A+ N ED+ LF + N
Sbjct: 2909 ----------ENVSKALVSAHKN-----EDIT--------------LFPRGGVAACVSHN 2939
Query: 1771 FE--GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYLLENV 1828
++ RAFCFLPL + TGLP HVN +F L S RR++W + G RSDWN L+ +
Sbjct: 2940 YKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVG---VRSDWNTNLMTLL 2996
Query: 1829 VAPAYGRLL 1837
+APA LL
Sbjct: 2997 IAPACVELL 3005
Score = 210 bits (534), Expect = 5e-52
Identities = 159/538 (29%), Positives = 270/538 (49%), Gaps = 91/538 (16%)
Query: 5 SPESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAG 64
+PE++ E GQ LT RI+ +L YP + KEL+QNADDA AT + +D R +
Sbjct: 1523 NPENLGFEQSGQREPLTVRIKNILEEYPSVADIFKELLQNADDASATECNFLIDMRKNND 1582
Query: 65 --DSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVY 122
++LL + GP+L ++N+AVF++ DF++I+++GGS K +A K G+FG+GFNSVY
Sbjct: 1583 IRENLLDPGMIACHGPSLWSFNNAVFSDTDFLNITRLGGSVKRSEADKVGKFGLGFNSVY 1642
Query: 123 HLTDLPSFVSGKYVVLFDPQGVYLPR--VSAANPGKRIDFT-GSSALSLYKDQFSPYC-A 178
H+TD+P +S +++++FDP ++ + +NPG +I+++ L + +QF P+
Sbjct: 1643 HITDIPIIMSREFMIIFDPNINHISKHIRDRSNPGIKINWSKQQKRLRKFPNQFKPFINV 1702
Query: 179 FGCDM----QSP--FAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQ--------- 223
FGC + SP F GTLFR P R +AS+S++S Y DI S+ +
Sbjct: 1703 FGCQLPLAQDSPYKFNGTLFRLPFRTEQEASQSEISSLYYNTTDIYSLVDEFSICGHRFI 1762
Query: 224 LFEE--GVLTLLFLK----------SVLCIEMYVWD------------AGEPKPKKIHS- 258
LF + G + L +LK V+ I VW A KK+ S
Sbjct: 1763 LFTQHVGGMVLKYLKYEDPDPAAAQDVVTINKSVWSSKASYGPLSILKAAAKVMKKVAST 1822
Query: 259 -----------CSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVR 307
C + + ++ + ++ L L +E D P ++ A +GV+T R
Sbjct: 1823 NKVPADIPKSGCIIRILVEEFHNVFKRIVDLHSPLFRGSEED--PNQYFEMAAKGVQTRR 1880
Query: 308 QVDRF---------YIVQTMASASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNND 358
D +++ + A+ + F+++ S + + L+P +A +S+ +
Sbjct: 1881 LTDEIPQKALEVTNWLICSCMDANEAL-KFSLSDSGK-RLGLVPCGGVAVLLSEEENHKW 1938
Query: 359 VLRT-----GQAFCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRL 413
++T G+ FC+LPL ++TGL V +NG F V+SNR+ IW D + WN +
Sbjct: 1939 TVKTNATPSGEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTD-------TKGQWNSV 1991
Query: 414 LLEDLVAPAFVHMLHGVK------ELLGPTDIYYSLWPTGS-FEEPWSILVQQIYINI 464
+ ++ A++ L ++ ELL T YY+ WP S + ++++ Q +Y I
Sbjct: 1992 FMRHVIVQAYLAALAMLRSMAENGELLDYT--YYAAWPDPSQVHDDFALISQGVYQEI 2047
Score = 62.0 bits (149), Expect = 2e-07
Identities = 43/138 (31%), Positives = 70/138 (50%), Gaps = 19/138 (13%)
Query: 1773 GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYLLENVVAPA 1832
G FC+LPL I TGLP H+N F ++SNR++IW +D G WN + +V+ A
Sbjct: 1948 GEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIW-KTDTKG------QWNSVFMRHVIVQA 2000
Query: 1833 YGRLLE--KVALEIGPC--YLFFSLWPKTLGL-EPWASVIRKLYQFVAE----FNLRVLY 1883
Y L + E G Y +++ WP + + +A + + +YQ +A+ + RV
Sbjct: 2001 YLAALAMLRSMAENGELLDYTYYAAWPDPSQVHDDFALISQGVYQEIAKGGDSEHARVF- 2059
Query: 1884 TEARGGQWISTKHAIFPD 1901
+ G W+S ++ F D
Sbjct: 2060 --SDGKTWVSIRYVRFLD 2075
>ref|XP_417138.1| PREDICTED: similar to sacsin [Gallus gallus]
Length = 4760
Score = 448 bits (1152), Expect = e-123
Identities = 468/1695 (27%), Positives = 745/1695 (43%), Gaps = 182/1695 (10%)
Query: 14 FGQTVD-LTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
FGQT L ++++L YPEG +LKELIQNA+DAGAT V D + ++L S +
Sbjct: 261 FGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVRFLYDETQYGTETLWSKDM 320
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+Q+QGPA AYNDA+FT +D+ I +I S K K GRFG+GFNSVYH+TD+PS S
Sbjct: 321 AQYQGPAFYAYNDAIFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPSIFS 380
Query: 133 GKYVVLFDP-QGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYC-AFGCDMQS----P 186
G + + DP Q ++ P S + D S ++ DQF+P+ FG ++
Sbjct: 381 GDQIGMLDPHQTLFGPHESGQCWNLKED---SKEINELTDQFAPFIGVFGSTKETFKNGN 437
Query: 187 FAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVW 246
F GT FRFPLR S+LS Y + + +F + LLFLKSV + ++V
Sbjct: 438 FPGTFFRFPLR----LQPSQLSSNVYDKQKVLELFESFRADADTVLLFLKSVQDVSLHVR 493
Query: 247 DAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTE-VDAFPLEFVTEAVRGV-- 303
+A + K I + S ++ L ++N + V + + VT V
Sbjct: 494 EA-DGTEKLIFRVTASENKALKHERPNSIKILGTAINQYCKGVPSNSITCVTYHVNIALE 552
Query: 304 -ETVRQVDR-FYIVQTMASASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLR 361
E+V+ + ++V A D++ +P IA +S N + +
Sbjct: 553 DESVKDAQKTSWLVCNCVGGRGMCTELDCLAD---DLKFVPTIGIAMPLSYNEKDKGAVA 609
Query: 362 --TGQAFCFLPLP----VRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLL 415
+G+AFCFLPLP +TGL V V+GFF ++ NRR I + ++D+ ++WN LL+
Sbjct: 610 DFSGRAFCFLPLPPGEESKTGLPVHVSGFFGLTDNRRSIKW-RELDQWRDPAALWNDLLV 668
Query: 416 EDLVAPAF-VHMLHGVKELLG--------PTDIYYSLWP-TGSFEEPWSILVQQIYINIC 465
++V A+ +L +K + + Y LWP PW +V ++ +
Sbjct: 669 VNIVPKAYSTLILEAIKRMETEENSDFPLSAERIYGLWPDENKIRVPWKPIVVPLFKELL 728
Query: 466 NAPVIYSNLGGGRWVSPSEAFLH--DEKFTKSKDLSLALMQLGMPVVHLPNSLFDML--- 520
VIYS +W+ + DE ++ + L G + +P ++ +
Sbjct: 729 QHTVIYS--VSNQWMKVEQVHFSEMDESLEYTQSVLNYLQNSGKQIAKVPANIASAVHFT 786
Query: 521 -LKYNSSKVITPGTVRQFLRECESCNHLSRAHKLLLLEYCLEDLVDDDVGKAAYNLPLLP 579
+ K +TP VRQ LR +S + KL LL++ L D V ++ L LLP
Sbjct: 787 TCTVKAVKKVTPAVVRQVLR--KSGHSGPAEEKLHLLQFVLSDGVYSEL----IGLELLP 840
Query: 580 LANGNFASFLE--ASKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSN- 636
L NGNF SF + + I Y ++ L + R++ + P +L L A S
Sbjct: 841 LQNGNFISFSSSVSEQDIVYITSEDFPRSLFPGLEGRLLSDDLKPEVLAALKEAAKSRAQ 900
Query: 637 -----------TNIALFSIHHFAHLFPVFMPDDWKYKCKVF-WDP--DSCQKPTSSWFVL 682
T + L + F L M W + V W P + P+ SW +
Sbjct: 901 QLLWGFSGRPCTQLQLLNPERFTRLIKEVMNSVWPGRDMVVQWYPGLEDKNHPSISWLKM 960
Query: 683 FWQYLGKQ-SEILPLFKDWPILP-------STSGHLLR---PSRQLKMINGST-LSDTVQ 730
W+ L S+ L F D P++P TS L+R PS + T L D +
Sbjct: 961 VWKNLYMHFSDDLSAFDDMPLIPKTLLEENQTSLELVRFRNPSPVILEDESETQLPDYIA 1020
Query: 731 DILVKIGCHILKPGYV-VEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEE 789
DI+ K+G +LK V ++HP + Y+ + VL+ + S + + SSL +
Sbjct: 1021 DIIEKVGGVVLKKLDVSIQHPLIKKYVHPPLPSAVLQIMEKV--SLQKLCNQVSSLPSTH 1078
Query: 790 RNELRRFLLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQD-SQFSDLENPRKYLPPL 848
++ LR FL + + E R + L I++ + ++ L +
Sbjct: 1079 KDALRAFLASL-----NDVSEKEGRIIQELLIFKKMEKSSDDGVPVYAGLNGSKVLHHTA 1133
Query: 849 DVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFD-RVGELQAEDRDSIM 907
+P + + ++ SS+ L+ +E++ K + D R ++ IM
Sbjct: 1134 KIPPGLRFSVP-VIDSSDEATIRLANLLKIEQLKSTDCLKFIIQDIRSCFYSYDETTQIM 1192
Query: 908 LSVLQNLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALL--EDSDSF 965
VL+NL L E+ + D L L+FI L + L+DP E + L E+ SF
Sbjct: 1193 QWVLENLTFLKNENTDVIDWLAALRFIRISEEKLMTANELFDPEVELLQNLFYSEEEISF 1252
Query: 966 PSGVFRESETLDIMRGLGLKT--SVSPDTVLESARCIEHLMHEDQQKAYLKGKVLFSYLE 1023
P +F S+ L +R +GLK+ ++ ++ A IE L H D
Sbjct: 1253 PPAIFTSSDILHSLRQIGLKSEANLEESDIMRVANKIESL-HADSNTDC----------- 1300
Query: 1024 VNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPVLVSPPFH 1083
D K + IL++ +S TK+ ++K I W P P +
Sbjct: 1301 --------DLLVRKARTLLMILNKNHKLLQSSETKTALKK-------IKWIPACKERPPN 1345
Query: 1084 ---SLPWPVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLGWMCPPGGGVI 1140
SL W + P + + LV + + ++ E + LG P I
Sbjct: 1346 YPGSLVWKGDHCNLCLPPEMCDISHAILVGSSVPLV--ENVQFDIEKALGISTKPS---I 1400
Query: 1141 AAQLLELGKNNEIVTD----QVLRQELALAMPRIYSILTGMIGSDEIEIVKAVLEGCR-- 1194
A L K+ ++V D + E I + G + D +E K + +
Sbjct: 1401 KAVL----KHFKVVVDWHSSKTFSDEDYYQFQHILLEIYGFM-HDHLEEGKEAFKALKFP 1455
Query: 1195 WIWVGDGFATSDEVVLD--GPLHLAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNIL 1252
W+W G F + + V+ L L PY+ +P +A F LF G E L P D+V+++
Sbjct: 1456 WVWTGKTFCSLTQAVIKTVPDLDLQPYLHYVPKTMAKFHQLFKCCGSIEQLTP-DHVSMV 1514
Query: 1253 FRMANKKGSSPLDTQEIRAVMLIVHHLAEVYLHGQKVQLYLPDVSGRLFLAGDLVYNDAP 1312
+ K L QE + + I+ + LY + L L P
Sbjct: 1515 IQKIYLKSEQSLSEQESKQNLHIMLSIIR--------WLYSNQIPASLHTPMPLYSGKLP 1566
Query: 1313 WLLGSED------PDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAE 1366
+ L D + + ++ + VH +I AE L V L L+
Sbjct: 1567 YKLVMRPIHECCYCDIKVDDLNDLLEDSVEPI-ILVHEDIPMKTAEWLNVPCLSTRLI-- 1623
Query: 1367 SADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLD 1426
+ ++M F E GQ E LT R+K+ILE Y EL+QNA+DA ASE FL+D
Sbjct: 1624 NPENMGF------EQSGQREPLTVRIKNILEEYPSISDIFKELLQNADDANASECNFLID 1677
Query: 1427 --KSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGL 1484
++ ++L P MA GPAL+ FN+S F+ D I+R+G+ K + +G+FGL
Sbjct: 1678 MRRNMDIRENLLDPGMAACHGPALWSFNNSEFSDSDFLNITRLGESLKRSEVDKVGKFGL 1737
Query: 1485 GFNCVYHFTDIPMFVSGENIVMFDPHASNLPG--ISPSHPGLRIKFA-GRKILEQFPDQF 1541
GFN VYH TD+P+ +S E ++MFDP+ +++ S+PG++I ++ +K L +FP+QF
Sbjct: 1738 GFNSVYHITDVPIILSREFMIMFDPNVNHIGKHIRDKSNPGIKINWSKQQKRLRKFPNQF 1797
Query: 1542 SSLLH-FGCDL------QHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSE 1594
+ FGC L + + GTLFR RT A S++ Y D+ SL FS
Sbjct: 1798 KPFIGVFGCQLPLTVESPYSYKGTLFRLSFRTQQEAKVSEVSNTCYNTADIYSLVDEFSI 1857
Query: 1595 VVSETLLFLRNVKSI 1609
++F ++V S+
Sbjct: 1858 CGHRLIIFAQSVNSM 1872
Score = 283 bits (723), Expect = 7e-74
Identities = 347/1458 (23%), Positives = 587/1458 (39%), Gaps = 208/1458 (14%)
Query: 13 DFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
+FGQ LT RI+ +L YP +LKEL+QNADDA AT + D R H D +
Sbjct: 2702 EFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPADRIFDEKW 2761
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+ QGPAL YN+ FTEDD I +G +K G KTG++G+GFNSVYH+TD PSF+S
Sbjct: 2762 APLQGPALCVYNNQPFTEDDIRGIQNLGKGTKVGNPCKTGQYGIGFNSVYHITDCPSFIS 2821
Query: 133 GKYVV-LFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTL 191
G ++ +FDP Y P ++ +PG+ + + + D Y + + T+
Sbjct: 2822 GNDILCIFDPHARYAPGATSTSPGRMFRDLDADFRTQFSDVLDLYLGDHFKLDN---CTM 2878
Query: 192 FRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEP 251
FRFPLRN + A S++S + + ++ +L +G L+FL + I + +
Sbjct: 2879 FRFPLRNGEMAKVSEISTVPCSDRMVQNLLDKLRTDGAELLMFLNHMEKISICEIEKTTG 2938
Query: 252 KPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVRQVDR 311
++S D + +Q + S+ ++ P++ +T + ++ +
Sbjct: 2939 ALNVLYSVQGKITDGDRLKRKQFHASVIDSVTKKKQLSEIPVQQITYTMDTEDSEGNLTT 2998
Query: 312 FYIVQTMA-SASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTGQAFCFLP 370
+ I SA ++ ++A K DI L P +AACI+ N + +AFCFLP
Sbjct: 2999 WLICNRSGFSAMEKVSKSVVSAHKNEDITLFPRGGVAACITHN-----YKKPHRAFCFLP 3053
Query: 371 LPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHML--- 427
L + TGL VNG F + S RR +W D+ VRS WN L+ L+APA+V +L
Sbjct: 3054 LSLETGLPFHVNGHFALDSARRNLWRDDN---GVGVRSDWNNSLMTALIAPAYVELLIQL 3110
Query: 428 --------------------HGVKELLGPTDIYYSLWPTG--SFEEPWSILVQQIYINIC 465
H VK+ L + S +P + W LV+ +Y I
Sbjct: 3111 KKRYFPGTDPTVSVLQNTPVHAVKDTLKK---FLSFFPVNRLDVQPDWYCLVKAVYSCIY 3167
Query: 466 N-----APVIYS-NLGGG--------RWVSPS---------EAFLHDE-KFTKSKDLSLA 501
PV+ + N+ G WV+ S + L DE + K+ + ++
Sbjct: 3168 EDLKRLLPVMRAPNVDGSDLHSAVIITWVNMSTVNKGRPFFDNLLQDELQHLKNTEYNIT 3227
Query: 502 ---------------LMQLGMPVVHLPN---SLFDMLLKYN-SSKVITPGTVRQFLREC- 541
L+++G +V+ + +L+ L+ + +TP VR FL
Sbjct: 3228 TRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLVDADIPVTYVTPADVRLFLMTFS 3287
Query: 542 ---ESCN-----------HLSRAHKL-LLLEYCLEDLVDDDVGKAAYNLPLLPLANGNFA 586
+C+ +L H L LL++YC +D ++++ LPLL + N
Sbjct: 3288 FPDSNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEENEI--QIEGLPLL-ITLDNVL 3344
Query: 587 SFLEASKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSNTNIALFSIHH 646
++ + P F+ ++L+ D ++ + R + I +SS+ +F I
Sbjct: 3345 QIFDSKR--PKFL--TTYHELIPSRKDLFMN-----TLYLRYNNILLSSDV-AKVFDIAS 3394
Query: 647 FAHLFPVFMPDDWKYKCKVFWDPDSCQKPTSSWFVLFWQYL--------------GKQSE 692
FA L +P ++K K + W + + SW W ++ K
Sbjct: 3395 FAELLSSVLPREYKTKSCMKWKENFA---SESWLKNAWHFISESIAVKEEQEDIQAKFDG 3451
Query: 693 ILPLFKDWPILPS-----TSGHLLRPSRQLKM--------INGSTLSDTVQDILVKIGCH 739
++ KDW +LP ++ HL+ P + + + + SD V L+K GC
Sbjct: 3452 VVETLKDWTLLPGVKFTVSANHLVVPECDVLLPLSIMHIAVFPNAQSDKVFHALMKTGCI 3511
Query: 740 ILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEE--RNELRRFL 797
L + L + A + ++ A V SS E+ ++ L
Sbjct: 3512 QLALNKICSKDSALVPLLSASTANIDNP--SSILKAIQYMVQTSSFRTEKLAESDFEALL 3569
Query: 798 LDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKYLPPLDVPEFILVG 857
+ + H + +I+ + LP Y+ S++ K +P ++V +
Sbjct: 3570 MYFNCNLCHLTSQDDIKILKSLPCYKSISGRYISISKYGTCYVLTKSIPSVEVDRWTQST 3629
Query: 858 IEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSIMLSVLQNLPLL 917
+ +D+ + G + + Y KH+ ++ L + D L L+N L
Sbjct: 3630 SSAFLEEKIHLKDLYT-VLGCVSVDDLEVYLKHLLPKIESL-SYDAKLEHLIYLKN-RLS 3686
Query: 918 SLEDAS-----IRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLEDSDSFPSGVFRE 972
S+E+ S + + L ++ I LK YD + +L + P F++
Sbjct: 3687 SIEETSEMKEQLFEKLESILIIHDASNRLKPAKYFYDRTVKVFEVMLPEKLFIPQDFFKK 3746
Query: 973 SETL--------------DIMRGLGLKTSVSPDTVLESARCIEHLMH-EDQQKAYLKG-- 1015
E + +R +GLK +S +L+ A+ I + E+ K L+
Sbjct: 3747 LEQITKPKSQAAFLPSWVTFLRHIGLKYIISQQQLLQFAKEISMRANTENWSKETLQNAV 3806
Query: 1016 KVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCP 1075
VL ++ L F + + + + A A R ++ L LI +
Sbjct: 3807 DVLLHHIFQERTDLLSGNFLKELSLIPFLCPERAPAEFVR-FHPQYQEVNGTLPLIRFNG 3865
Query: 1076 VLVSPPFH-----SLPWPVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLG 1130
V+P F L W S + P K L + LD + +L L
Sbjct: 3866 AQVNPKFKQTDVLQLLW--TSCPILPEKA----TPLSIKEQEGSTLDMQEQLEQVLTMLS 3919
Query: 1131 WMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVKAVL 1190
P + + N D+ + + A + IY L S E + L
Sbjct: 3920 VNLDPPLDKVINNCRNI--CNITTVDEEMVKTRAKILRSIYEFL-----STEKREFRFQL 3972
Query: 1191 EGCRWIWVGDGF--ATSDEVV--LDGPLHLAPYIRVIPVDLAVFKNLFLELGIREFLQPS 1246
G ++ V +G+ +EVV L+ PY+ +P++L F LF LG + +
Sbjct: 3973 RGVSFVMVEEGWKLLKPEEVVINLEYESDFKPYLYKLPLELGTFHQLFKHLGTEDVISTK 4032
Query: 1247 DYVNILFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYLHGQKVQ------------LYLP 1294
YV +L R+ LD E+R V +V L + L V+ LYLP
Sbjct: 4033 QYVEVLGRIFKNSEGKQLDPNEMRTVKRVVSGLFK-SLQNDSVKVRNDLENMRDFALYLP 4091
Query: 1295 DVSGRLFLAGDLVYNDAP 1312
GRL + LV++DAP
Sbjct: 4092 SQDGRLVKSSILVFDDAP 4109
Score = 263 bits (673), Expect = 4e-68
Identities = 247/902 (27%), Positives = 409/902 (44%), Gaps = 129/902 (14%)
Query: 1382 FGQHEA-LTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLDKSQYGTSSVLSPEM 1440
FGQ L LK IL Y +G L EL+QNAEDAGA+EV FL D++QYGT ++ S +M
Sbjct: 261 FGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVRFLYDETQYGTETLWSKDM 320
Query: 1441 ADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVS 1500
A +QGPA Y +ND++FTP+D + I I + K + +GRFG+GFN VYH TD+P S
Sbjct: 321 AQYQGPAFYAYNDAIFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPSIFS 380
Query: 1501 GENIVMFDPHASNLPGISPSHPGLRIKFAGRKILEQFPDQFSSLLH-FGCDLQ----HPF 1555
G+ I M DPH L G S +K ++I + DQF+ + FG + F
Sbjct: 381 GDQIGMLDPH-QTLFGPHESGQCWNLKEDSKEI-NELTDQFAPFIGVFGSTKETFKNGNF 438
Query: 1556 PGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISIFLKE 1615
PGT FRFPLR SQ+ VY + V LF +F LLFL++V+ +S+ ++E
Sbjct: 439 PGTFFRFPLR----LQPSQLSSNVYDKQKVLELFESFRADADTVLLFLKSVQDVSLHVRE 494
Query: 1616 GTGHEMRLLHRVSRASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLSLSIDRDLP 1675
G E +L+ RV+ + A + N K ++G Q+ K + + +
Sbjct: 495 ADGTE-KLIFRVTASE------NKALKHERPNSIK---ILGTAINQYCKGVPSNSITCVT 544
Query: 1676 YKCQKILITEQGTHGRNSHYWIMTECLGGGNVLKGTSEASTSNSHNFVPWACVAAYLNSV 1735
Y I + ++ W++ C+GG + T ++ FVP +A L+
Sbjct: 545 YHV-NIALEDESVKDAQKTSWLVCNCVGGRGMC--TELDCLADDLKFVPTIGIAMPLSYN 601
Query: 1736 KHGEDLVDSAEVEDDCLVSSDLFQFASLPMHPRENFEGRAFCFLPLP----ISTGLPAHV 1791
+ D V D F GRAFCFLPLP TGLP HV
Sbjct: 602 EK-----DKGAVAD---------------------FSGRAFCFLPLPPGEESKTGLPVHV 635
Query: 1792 NAYFELSSNRRDI-WFGSDMTGGGRKRSDWNIYLLENVVAPAYGRL----LEKVALEIGP 1846
+ +F L+ NRR I W ++ + WN L+ N+V AY L ++++ E
Sbjct: 636 SGFFGLTDNRRSIKW--RELDQWRDPAALWNDLLVVNIVPKAYSTLILEAIKRMETEENS 693
Query: 1847 CY-----LFFSLWPKTLGLE-PWASVIRKLYQFVAEFNLRVLYTEARGGQWISTKHAIFP 1900
+ + LWP + PW ++ L++ + + V+Y+ + QW+ + F
Sbjct: 694 DFPLSAERIYGLWPDENKIRVPWKPIVVPLFKELLQHT--VIYSVS--NQWMKVEQVHFS 749
Query: 1901 --DFSFPKADELIKALSGASLPVITLPQSLLERFMEICPSLHF----------LKPKLLR 1948
D S ++ L + + +P + I ++HF + P ++R
Sbjct: 750 EMDESLEYTQSVLNYLQNSGKQIAKVPAN-------IASAVHFTTCTVKAVKKVTPAVVR 802
Query: 1949 TLLIRRKREFKDRDAMILTLEYCLHDFEESMQFDTLGGLPLLPLADGSFTSIEMKGIGER 2008
+L R+ + + L++ L D + L GL LLPL +G+F S + E+
Sbjct: 803 QVL-RKSGHSGPAEEKLHLLQFVLSD----GVYSELIGLELLPLQNGNFISFS-SSVSEQ 856
Query: 2009 --VYIARGD---------EYGLLRDSIPHQLVDCV---IPKEVHRKLCYIAQTDSTNISF 2054
VYI D E LL D + +++ + + L + T +
Sbjct: 857 DIVYITSEDFPRSLFPGLEGRLLSDDLKPEVLAALKEAAKSRAQQLLWGFSGRPCTQLQL 916
Query: 2055 LSCQLLEKLLVKLLPVEWQHASL-VSWTPGIH--GQPSLEWLQLLWNYLKAN-CDDLLMF 2110
L+ + +L+ +++ W + V W PG+ PS+ WL+++W L + DDL F
Sbjct: 917 LNPERFTRLIKEVMNSVWPGRDMVVQWYPGLEDKNHPSISWLKMVWKNLYMHFSDDLSAF 976
Query: 2111 SKWPILP----VGDDCLIQL----KPNLNVIKNDGWS---EKMSSLLVKVGCLFLRP-DL 2158
P++P + ++L P+ +++++ + + ++ ++ KVG + L+ D+
Sbjct: 977 DDMPLIPKTLLEENQTSLELVRFRNPSPVILEDESETQLPDYIADIIEKVGGVVLKKLDV 1036
Query: 2159 QLDHPKLECFVQSPTARGVLNVFLAVAGEPQKIEGIFTDASDGELHELRSFILQSKWFSE 2218
+ HP ++ +V P VL + V+ QK+ + LR+F+ SE
Sbjct: 1037 SIQHPLIKKYVHPPLPSAVLQIMEKVS--LQKLCNQVSSLPSTHKDALRAFLASLNDVSE 1094
Query: 2219 EQ 2220
++
Sbjct: 1095 KE 1096
Score = 248 bits (632), Expect = 2e-63
Identities = 265/1030 (25%), Positives = 427/1030 (40%), Gaps = 161/1030 (15%)
Query: 843 KYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAED 902
K L +D+P ++ G E + + +L + + QF+ + F V E+ AE
Sbjct: 2204 KNLCAVDLPSWVKTGFE----EAGCKHILLENTFS-----EKQFFSEVFFPNVQEIAAEL 2254
Query: 903 RDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIG--TLKCPSVLYDPRNEEIYALLE 960
RD +M VL LE+ S +LR IP + L PS L P
Sbjct: 2255 RDPLMRYVLNE----KLEEFS--GILRITPCIPCSLDGHPLVTPSRLIHPEGRVAKLYDA 2308
Query: 961 DSDSFPSGVFRE---SETLDIMRGLGL-KTSVSPDTVLESARCIEHLMHEDQQKAYLKGK 1016
+ FP G ++ L + LG+ K + + ++E A + + D A L+
Sbjct: 2309 EDGRFPYGTTQDYLNPVILVKLVQLGMAKDDILWEDLIERAESVAEINKVDHAAACLRSS 2368
Query: 1017 VLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPV 1076
++ S + D+K + R+ ++ ++F Q I + P
Sbjct: 2369 IILSLI------------DEK--------------LKCRDPRA--KEFAEKCQTIPFLPF 2400
Query: 1077 LVSPPFHSLPWPVVSSMVAPPKVVRPPNDLW------LVSAGMRILDGECSS-------- 1122
L P SL W PP + DL+ +V IL+ S
Sbjct: 2401 LSKPAGFSLHW---KGSDFPPDAMFSATDLFTADHQDIVCLIQPILNENSHSFKGCGALS 2457
Query: 1123 TALLYCLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDE 1182
A+ LG + P ++ QL E+ K+ + +T + ++ + A + + M+ ++
Sbjct: 2458 LAVKEFLGLLKKPAVNLVINQLEEVAKSFDGIT--LYQENITNACYK--HLHEAMLENES 2513
Query: 1183 IE-IVKAVLEGCRWIWVGDGFATSDEVVLDGPLHLAPYIRVIPVDLA-VFKNLFLELGIR 1240
+ ++ L C +I V + + +V APY+ +P F+ LF +G+R
Sbjct: 2514 TKAMIIEQLTNCSFILVENVYVDPTKVSFHLNFEAAPYLYQLPNKYKNSFRELFESMGVR 2573
Query: 1241 EFLQPSDYVNILFRMANKKGSSPLDTQEIR--------AVMLIVHHLAEVYLHGQKVQLY 1292
+ D+ +L + ++G+ L + + + ++ + + + ++
Sbjct: 2574 QSFTVEDFALVLELINQERGTKQLTEENFQLCRRIISEGIWSLIREKKQEFCVKKYGEIL 2633
Query: 1293 LPDVSGRLFLAGDLVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAE 1352
LPD L A L YND PW+ K T K+ H +I +VA
Sbjct: 2634 LPDTRFALLPAKSLCYNDCPWI------------------KVKDTTVKYCHADIPREVAV 2675
Query: 1353 KLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQN 1412
KLG R L A ++ F G FGQ E LT+R+K IL Y L EL+QN
Sbjct: 2676 KLGAIPKRHKALERYASNICFTTLGTE--FGQKEKLTSRIKSILNAYPSEKEMLKELLQN 2733
Query: 1413 AEDAGASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESK 1472
A+DA A+E+ F+ D Q+ + + A QGPAL +N+ FT D+ I +G+ +K
Sbjct: 2734 ADDAKATEICFVFDPRQHPADRIFDEKWAPLQGPALCVYNNQPFTEDDIRGIQNLGKGTK 2793
Query: 1473 LEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIV-MFDPHASNLPGISPSHPGLRIKFAGR 1531
+ G++G+GFN VYH TD P F+SG +I+ +FDPHA PG + + PG +
Sbjct: 2794 VGNPCKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSTSPGRMFRDLDA 2853
Query: 1532 KILEQFPDQFSSLL--HFGCDLQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLF 1589
QF D L HF D T+FRFPLR +A S+I + V++L
Sbjct: 2854 DFRTQFSDVLDLYLGDHFKLD-----NCTMFRFPLRNGEMAKVSEISTVPCSDRMVQNLL 2908
Query: 1590 AAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFNFF 1649
+E L+FL +++ ISI E T + +L+ V G+ G + F+
Sbjct: 2909 DKLRTDGAELLMFLNHMEKISICEIEKTTGALNVLYSVQ----GKITDGDRLKRKQFHAS 2964
Query: 1650 KEDRLVGMNRAQFLKKLSLSIDRDLPYKCQKILITEQGTHGRNSHYWIMTECLGGGNVLK 1709
D + KK LS ++P + + + + G N W++
Sbjct: 2965 VIDSVT--------KKKQLS---EIPVQQITYTMDTEDSEG-NLTTWLI----------- 3001
Query: 1710 GTSEASTSNSHNFVPWACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMHPRE 1769
N F V+ + S ED+ LF +
Sbjct: 3002 -------CNRSGFSAMEKVSKSVVSAHKNEDIT--------------LFPRGGVAACITH 3040
Query: 1770 NFE--GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYLLEN 1827
N++ RAFCFLPL + TGLP HVN +F L S RR++W + G RSDWN L+
Sbjct: 3041 NYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVG---VRSDWNNSLMTA 3097
Query: 1828 VVAPAYGRLL 1837
++APAY LL
Sbjct: 3098 LIAPAYVELL 3107
Score = 154 bits (389), Expect = 3e-35
Identities = 86/246 (34%), Positives = 147/246 (58%), Gaps = 12/246 (4%)
Query: 5 SPESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAG 64
+PE++ E GQ LT RI+ +L YP + + KEL+QNADDA A+ + +D R +
Sbjct: 1624 NPENMGFEQSGQREPLTVRIKNILEEYPSISDIFKELLQNADDANASECNFLIDMRRNMD 1683
Query: 65 --DSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVY 122
++LL ++ GPAL ++N++ F++ DF++I+++G S K + K G+FG+GFNSVY
Sbjct: 1684 IRENLLDPGMAACHGPALWSFNNSEFSDSDFLNITRLGESLKRSEVDKVGKFGLGFNSVY 1743
Query: 123 HLTDLPSFVSGKYVVLFDPQGVYLPR--VSAANPGKRIDFT-GSSALSLYKDQFSPYC-A 178
H+TD+P +S +++++FDP ++ + +NPG +I+++ L + +QF P+
Sbjct: 1744 HITDVPIILSREFMIMFDPNVNHIGKHIRDKSNPGIKINWSKQQKRLRKFPNQFKPFIGV 1803
Query: 179 FGCDM----QSPFA--GTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTL 232
FGC + +SP++ GTLFR R +A S++S Y DI S+ + G +
Sbjct: 1804 FGCQLPLTVESPYSYKGTLFRLSFRTQQEAKVSEVSNTCYNTADIYSLVDEFSICGHRLI 1863
Query: 233 LFLKSV 238
+F +SV
Sbjct: 1864 IFAQSV 1869
Score = 66.6 bits (161), Expect = 1e-08
Identities = 55/230 (23%), Positives = 99/230 (42%), Gaps = 46/230 (20%)
Query: 340 LLPWASIAACISDNSLNNDVLRT-----GQAFCFLPLPVRTGLSVQVNGFFEVSSNRRGI 394
L+P +A +++ +++ G+ FC+LPL ++TGL + +NG F V+SNR+ I
Sbjct: 2022 LVPCGGVAVLLTETQDQKWIVKPNCNNIGEVFCYLPLRIKTGLPLHINGCFAVTSNRKEI 2081
Query: 395 WYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHMLHGVKELLGPTDI----YYSLWP-TGSF 449
W D R WN + + ++ A++ L ++++ ++ Y ++WP S
Sbjct: 2082 WKTDTKGR-------WNTVFMRHVIVKAYIEALCVLRDMAISGELVDYSYCAVWPDPDSV 2134
Query: 450 EEPWSILVQQIYINICNAP-----VIYSNLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQ 504
+ +S++ Q Y +I + ++S+ G WVS D+ K D+
Sbjct: 2135 HDDFSVICQGFYEDIAHMKSKEGIKVFSD--GISWVSMKNVRFLDDSILKRPDVG----- 2187
Query: 505 LGMPVVHLPNSLFDMLLKY-------NSSKVITPGTVRQFLRECESCNHL 547
S F + LKY N V P V+ E C H+
Sbjct: 2188 ---------PSAFKIFLKYLKKTGSKNLCAVDLPSWVKTGFEEA-GCKHI 2227
Score = 63.5 bits (153), Expect = 8e-08
Identities = 60/226 (26%), Positives = 96/226 (41%), Gaps = 39/226 (17%)
Query: 1692 NSHYWIMTECLGGGNVLKGTSEASTSNSHNFVPWACVAAYLNSVKHGEDLVDSAEVEDDC 1751
+S W++ C+ G+ LK + S VP VA L + + +V
Sbjct: 1993 DSTTWLICSCMDTGDALKFSLHES-GRRLGLVPCGGVAVLLTETQDQKWIVK-------- 2043
Query: 1752 LVSSDLFQFASLPMHPRENFEGRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMT 1811
P N G FC+LPL I TGLP H+N F ++SNR++IW +D
Sbjct: 2044 ---------------PNCNNIGEVFCYLPLRIKTGLPLHINGCFAVTSNRKEIW-KTDTK 2087
Query: 1812 GGGRKRSDWNIYLLENVVAPAYGR---LLEKVALEIGPC--YLFFSLWPKTLGLEPWASV 1866
G WN + +V+ AY +L +A+ G Y + ++WP + SV
Sbjct: 2088 G------RWNTVFMRHVIVKAYIEALCVLRDMAIS-GELVDYSYCAVWPDPDSVHDDFSV 2140
Query: 1867 I-RKLYQFVAEFNLRV-LYTEARGGQWISTKHAIFPDFSFPKADEL 1910
I + Y+ +A + + + G W+S K+ F D S K ++
Sbjct: 2141 ICQGFYEDIAHMKSKEGIKVFSDGISWVSMKNVRFLDDSILKRPDV 2186
>emb|CAI13923.1| spastic ataxia of Charlevoix-Saguenay (sacsin) [Homo sapiens]
Length = 4579
Score = 442 bits (1138), Expect = e-122
Identities = 466/1700 (27%), Positives = 753/1700 (43%), Gaps = 199/1700 (11%)
Query: 14 FGQTVD-LTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
FGQT L ++++L YPEG +LKELIQNA+DAGAT V D + ++L S +
Sbjct: 89 FGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDM 148
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+ +QGPAL YN+AVFT +D+ I +I S K K GRFG+GFNSVYH+TD+P S
Sbjct: 149 APYQGPALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFS 208
Query: 133 GKYVVLFDP-QGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCA-FGCDMQS----P 186
G + + DP Q ++ P S + D S +S DQF+P+ FG ++
Sbjct: 209 GDQIGMLDPHQTLFGPHESGQCWNLKDD---SKEISELSDQFAPFVGIFGSTKETFINGN 265
Query: 187 FAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVW 246
F GT FRFPLR S+LS Y + + +F + LLFLKSV + +YV
Sbjct: 266 FPGTFFRFPLR----LQPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQDVSLYVR 321
Query: 247 DAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETV 306
+A + V+S + H + + P +T V V
Sbjct: 322 EADGTEKLVFR---VTSSESKALKHERPNSIKILGTAISNYCKKTPSNNITCVTYHVNIV 378
Query: 307 RQVDRFYIVQ-TMASASSRIGSFAITASKEY---DIQLLPWASIAACIS---DNSLNNDV 359
+ + Q T + +G I++ + +++ +P IA +S D +
Sbjct: 379 LEEESTKDAQKTSWLVCNSVGGRGISSKLDSLADELKFVPIIGIAMPLSSRDDEAKGATS 438
Query: 360 LRTGQAFCFLPLPV----RTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLL 415
+G+AFCFLPLP TGL V ++GFF ++ NRR I + + +D+ ++WN L+
Sbjct: 439 DFSGKAFCFLPLPPGEESSTGLPVHISGFFGLTDNRRSIKWRE-LDQWRDPAALWNEFLV 497
Query: 416 EDLVAPAFVHM-LHGVKELLGP--------TDIYYSLWPTGS-FEEPWSILVQQIYINIC 465
++V A+ + L +K L D+ Y LWP S + W +++ ++ +
Sbjct: 498 MNVVPKAYATLILDSIKRLEMEKSSDFPLSVDVIYKLWPEASKVKVHWQPVLEPLFSELL 557
Query: 466 NAPVIYSNLGGGRWVSPSEAFLH--DEKFTKSKDLSLALMQLGMPVVHLPNSLFDMLLKY 523
VIYS WV + + DE +K + L G + +P ++ D ++
Sbjct: 558 QNAVIYSI--SCDWVRLEQVYFSELDENLEYTKTVLNYLQSSGKQIAKVPGNV-DAAVQL 614
Query: 524 NSS------KVITPGTVRQFLRECESCNHLSRAH-KLLLLEYCLEDLVDDDVGKAAYNLP 576
++ + +TP VRQ LR+C HL A KL LLE+ L D ++ L
Sbjct: 615 TAASGTTPVRKVTPAWVRQVLRKCA---HLGCAEEKLHLLEFVLSDQAYSEL----LGLE 667
Query: 577 LLPLANGNFASFLEA--SKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMS 634
LLPL NGNF F + + + Y E L + R I ++ P+++ L A +
Sbjct: 668 LLPLQNGNFVPFSSSVSDQDVIYITSAEYPRSLFPSLEGRFILDNLKPHLVAALKEAAQT 727
Query: 635 SN---TNIALFSIHHFAHLFPVFMPDDWKYK-CKVFWDP--DSCQKPTSSWFVLFWQYLG 688
T + L + FA L M W + V W P ++ P+ SW + W+ L
Sbjct: 728 RGRPCTQLQLLNPERFARLIKEVMNTFWPGRELIVQWYPFDENRNHPSVSWLKMVWKNLY 787
Query: 689 KQ-SEILPLFKDWPILPST---SGHLLRPSRQLKMINGSTLSDTVQ--------DILVKI 736
SE L LF + P++P T G +L++ + L D + DI+ K+
Sbjct: 788 IHFSEDLTLFDEMPLIPRTILEEGQTCVELIRLRIPSLVILDDESEAQLPEFLADIVQKL 847
Query: 737 GCHILKP-GYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEERNELRR 795
G +LK ++HP + Y+ + VL+ + + + +SL+ ++ LR+
Sbjct: 848 GGFVLKKLDASIQHPLIKKYIHSPLPSAVLQIMEKM--PLQKLCNQITSLLPTHKDALRK 905
Query: 796 FLLDPQWYVGHSMDEFNIRFCRRLPIYQ-VYHREPTQDSQFSDLENPRKYLPPLDVPEFI 854
FL E R + L I++ + H S ++ L+ + +P +
Sbjct: 906 FLASLT-----DSSEKEKRIIQELAIFKRINHSSDQGISSYTKLKGCKVLHHTAKLPADL 960
Query: 855 LVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQA-EDRDSIMLSVLQN 913
+ I ++ SS+ L+ +E++ K + D + E+ +ML VL+N
Sbjct: 961 RLSIS-VIDSSDEATIRLANMLKIEQLKTTSCLKLVLKDIENAFYSHEEVTQLMLWVLEN 1019
Query: 914 LPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALL--EDSDSFPSGVFR 971
L L E+ ++ + L LKFI + L+DP E + L E+ FP VF
Sbjct: 1020 LSSLKNENPNVLEWLTPLKFIQISQEQMVSAGELFDPDIEVLKDLFCNEEGTYFPPSVFT 1079
Query: 972 ESETLDIMRGLGLKT--SVSPDTVLESARCIEHLMH---EDQQKAYLKGKVLFSYLEVNA 1026
+ L +R +GLK S+ V++ A+ IE L DQ K K L L N
Sbjct: 1080 SPDILHSLRQIGLKNEASLKEKDVVQVAKKIEALQVGACPDQDVLLKKAKTLLLVLNKNH 1139
Query: 1027 LKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPVLVSPPFH--- 1083
T +S K ++K I W P P +
Sbjct: 1140 -----------------------TLLQSSEGKMTLKK-------IKWVPACKERPPNYPG 1169
Query: 1084 SLPWPV-VSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLGWMCPPGGGVIAA 1142
SL W + ++ APP + + + L+ + + ++ E L LG P +
Sbjct: 1170 SLVWKGDLCNLCAPPDMCDVGHAI-LIGSSLPLV--ESIHVNLEKALGIFTKPSLSAVLK 1226
Query: 1143 --QLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMI--GSDEIEIVKAVLEGCRWIWV 1198
+++ +++ +D+ Q + + IY + + G D +K W+W
Sbjct: 1227 HFKIVVDWYSSKTFSDEDYYQFQHILL-EIYGFMHDHLNEGKDSFRALKFP-----WVWT 1280
Query: 1199 GDGFATSDEVVLDGPLH---LAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFRM 1255
G F + V+ P+H L PY+ +P +A F LF G E L SD+++++ +
Sbjct: 1281 GKKFCPLAQAVIK-PIHDLDLQPYLHNVPKTMAKFHQLFKVCGSIEELT-SDHISMVIQK 1338
Query: 1256 ANKKGSSPLDTQEIRAVMLIVHHLAEVYLHGQ-------KVQLYLPDVSGRLFLAG---- 1304
K L QE + + ++ ++ Q V ++ +L +
Sbjct: 1339 IYLKSDQDLSEQESKQNLHLMLNIIRWLYSNQIPASPNTPVPIHHSKNPSKLIMKPIHEC 1398
Query: 1305 ---DLVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRR 1361
D+ +D LL ED P + VH +I AE L V L
Sbjct: 1399 CYCDIKVDDLNDLL--ED-----SVEPII----------LVHEDIPMKTAEWLKVPCLST 1441
Query: 1362 MLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASEV 1421
L+ + ++M F E GQ E LT R+K+ILE Y EL+QNA+DA A+E
Sbjct: 1442 RLI--NPENMGF------EQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATEC 1493
Query: 1422 IFLLD--KSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAI 1479
FL+D ++ ++L P MA GPAL+ FN+S F+ D I+R+G+ K + +
Sbjct: 1494 SFLIDMRRNMDIRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRGEVDKV 1553
Query: 1480 GRFGLGFNCVYHFTDIPMFVSGENIVMFDPHASNLPG--ISPSHPGLRIKFA-GRKILEQ 1536
G+FGLGFN VYH TDIP+ +S E ++MFDP+ +++ S+PG++I ++ +K L +
Sbjct: 1554 GKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRK 1613
Query: 1537 FPDQFSSLLH-FGCDL------QHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLF 1589
FP+QF + FGC L + + GTLFR RT A S++ Y D+ SL
Sbjct: 1614 FPNQFKPFIDVFGCQLPLTVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLV 1673
Query: 1590 AAFSEVVSETLLFLRNVKSI 1609
FS ++F ++VKS+
Sbjct: 1674 DEFSLCGHRLIIFTQSVKSM 1693
Score = 291 bits (744), Expect = 2e-76
Identities = 349/1460 (23%), Positives = 589/1460 (39%), Gaps = 212/1460 (14%)
Query: 13 DFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
+FGQ LT RI+ +L YP +LKEL+QNADDA AT + D R H D +
Sbjct: 2521 EFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKW 2580
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+ QGPAL YN+ FTEDD I +G +K G KTG++G+GFNSVYH+TD PSF+S
Sbjct: 2581 APLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPYKTGQYGIGFNSVYHITDCPSFIS 2640
Query: 133 GKYVV-LFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTL 191
G ++ +FDP Y P ++ +PG+ + + + D Y + + T+
Sbjct: 2641 GNDILCIFDPHARYAPGATSISPGRMFRDLDADFRTQFSDVLDLYLGTHFKLDNC---TM 2697
Query: 192 FRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEP 251
FRFPLRNA+ A S++S + + ++ +L +G L+FL + I + D
Sbjct: 2698 FRFPLRNAEMAKVSEISSVPASDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKSTG 2757
Query: 252 KPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVRQVDR 311
++S D + +Q + S+ ++ P++ +T + ++ +
Sbjct: 2758 ALNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTT 2817
Query: 312 FYIVQTMA-SASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTGQAFCFLP 370
+ I S+ ++ I+A K DI L P +AACI+ N + +AFCFLP
Sbjct: 2818 WLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACITHN-----YKKPHRAFCFLP 2872
Query: 371 LPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHM---- 426
L + TGL VNG F + S RR +W D+ VRS WN L+ L+APA+V +
Sbjct: 2873 LSLETGLPFHVNGHFALDSARRNLWRDDN---GVGVRSDWNNSLMTALIAPAYVELLIQL 2929
Query: 427 -------------------LHGVKELLGPTDIYYSLWPTGSFEEPWSI--LVQQIYINIC 465
+H VK+ L + S +P + + LV+ +Y I
Sbjct: 2930 KKRYFPGSDPTLSVLQNTPIHVVKDTLKK---FLSFFPVNRLDLQPDLYCLVKALYNCIH 2986
Query: 466 N-----APVIYS-NLGGG--------RWVSPSEA---------FLHDE-KFTKSKDLSLA 501
PV+ + N+ G W++ S + L DE + K+ D ++
Sbjct: 2987 EDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTRPFFDNLLQDELQHLKNADYNIT 3046
Query: 502 ---------------LMQLGMPVVHLPN---SLFDMLLKYNSS-KVITPGTVRQFLRECE 542
L+++G +V+ + +L+ L+ + +TP +R FL
Sbjct: 3047 TRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLIDADIPVSYVTPADIRSFLMTFS 3106
Query: 543 S----CN-----------HLSRAHKL-LLLEYCLEDLVDDDVGKAAYNLPLLPLANGNFA 586
S C+ +L H L LL++YC +D ++++ LPLL +
Sbjct: 3107 SPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEENEI--EVEGLPLLITLDSVLQ 3164
Query: 587 SFLEASKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSNTNIA-LFSIH 645
+F +A + P F+ ++L+ D ++ + + S I + N +A +F I
Sbjct: 3165 TF-DAKR--PKFLTTY--HELIPSRKDLFMN-----TLYLKYSNILL--NCKVAKVFDIS 3212
Query: 646 HFAHLFPVFMPDDWKYKCKVFWDPDSCQKPTSSWFVLFWQYLGK-------QSEILPLF- 697
FA L +P ++K K W + + SW W ++ + Q E P F
Sbjct: 3213 SFADLLSSVLPREYKTKSCTKWKDNFASE---SWLKNAWHFISESVSVKEDQEETKPTFD 3269
Query: 698 ------KDWPILPST------------SGHLLRPSRQLKM-INGSTLSDTVQDILVKIGC 738
KDW +LP T G +L P + + + + SD V L+K GC
Sbjct: 3270 IVVDTLKDWALLPGTKFTVSANQLVVPEGDVLLPLSLMHIAVFPNAQSDKVFHALMKAGC 3329
Query: 739 HILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEE--RNELRRF 796
L + F L + A + + A + V S+ AE+ N+
Sbjct: 3330 IQLALNKICSKDSAFVPLLSCHTANIESP--TSILKALHYMVQTSTFRAEKLVENDFEAL 3387
Query: 797 LLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKYLPPLDVPEFILV 856
L+ + H M + +I+ + LP Y+ +F K +P +V ++
Sbjct: 3388 LMYFNCNLNHLMSQDDIKILKSLPCYKSISGRYVSIGKFGTCYVLTKSIPSAEVEKWTQS 3447
Query: 857 GIE-FIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSIMLSV---LQ 912
F+ + +E L G + + Y KH+ ++ L + + ++ + L
Sbjct: 3448 SSSAFLEEKIHLKE--LYEVIGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLS 3505
Query: 913 NLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLEDSDSFPSGVFRE 972
+ LS + + L +L I LK YD +L + P+ F++
Sbjct: 3506 SAEELSEIKEQLFEKLESLLIIHDANSRLKQAKHFYDRTVRVFEVMLPEKLFIPNDFFKK 3565
Query: 973 SETL--------------DIMRGLGLKTSVSPDTVLESARCIE-HLMHEDQQKAYLKGKV 1017
E L + +R +GLK +S +L+ A+ I E+ K L+ V
Sbjct: 3566 LEQLIKPKNHVTFMTSWVEFLRNIGLKYILSQQQLLQFAKEISVRANTENWSKETLQNTV 3625
Query: 1018 --LFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCP 1075
L ++ + L F + + + + A A R ++ L LI +
Sbjct: 3626 DILLHHIFQERMDLLSGNFLKELSLIPFLCPERAPAEFIR-FHPQYQEVNGTLPLIKFNG 3684
Query: 1076 VLVSPPFH-----SLPW---PVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLY 1127
V+P F L W P++ P + G + E L
Sbjct: 3685 AQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKE--------QEGSDLGPQEQLEQVLNM 3736
Query: 1128 CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVK 1187
+ PP VI I L +E+ ++ + + +++ E +
Sbjct: 3737 LNVNLDPPLDKVI-------NNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREF-R 3788
Query: 1188 AVLEGCRWIWVGDGF--ATSDEVV--LDGPLHLAPYIRVIPVDLAVFKNLFLELGIREFL 1243
L G ++ V DG+ +EVV L+ PY+ +P++L F LF LG + +
Sbjct: 3789 FQLRGVAFVMVEDGWKLLKPEEVVINLEYESDFKPYLYKLPLELGTFHQLFKHLGTEDII 3848
Query: 1244 QPSDYVNILFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYLHG-----------QKVQLY 1292
YV +L R+ LD E+R V +V L + + + LY
Sbjct: 3849 STKQYVEVLSRIFKNSEGKQLDPNEMRTVKRVVSGLFRSLQNDSVKVRSDLENVRDLALY 3908
Query: 1293 LPDVSGRLFLAGDLVYNDAP 1312
LP GRL + LV++DAP
Sbjct: 3909 LPSQDGRLVKSSILVFDDAP 3928
Score = 266 bits (681), Expect = 5e-69
Identities = 243/854 (28%), Positives = 402/854 (46%), Gaps = 103/854 (12%)
Query: 1374 GLSGAAEAFGQHEA-LTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLDKSQYGT 1432
GL G FGQ L LK IL Y +G L EL+QNAEDAGA+EV FL D++QYGT
Sbjct: 82 GLKGGGR-FGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGT 140
Query: 1433 SSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHF 1492
++ S +MA +QGPALY +N++VFTP+D + I I + K + +GRFG+GFN VYH
Sbjct: 141 ETLWSKDMAPYQGPALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHI 200
Query: 1493 TDIPMFVSGENIVMFDPHASNLPGISPSHPGLRIKFAGRKILEQFPDQFSSLLH-FGCD- 1550
TD+P SG+ I M DPH L G S +K ++I E DQF+ + FG
Sbjct: 201 TDVPCIFSGDQIGMLDPH-QTLFGPHESGQCWNLKDDSKEISE-LSDQFAPFVGIFGSTK 258
Query: 1551 ---LQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVK 1607
+ FPGT FRFPLR SQ+ +Y + V LF +F LLFL++V+
Sbjct: 259 ETFINGNFPGTFFRFPLR----LQPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQ 314
Query: 1608 SISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLS 1667
+S++++E G E +L+ RV+ + ES+ E + +++G + + KK
Sbjct: 315 DVSLYVREADGTE-KLVFRVTSS---ESKALKHERPNSI------KILGTAISNYCKKTP 364
Query: 1668 LSIDRDLPYKCQKILITEQGTHGRNSHYWIMTECLGGGNVLKGTSEASTSNSHNFVPWAC 1727
+ + Y I++ E+ T W++ +GG + + S ++ FVP
Sbjct: 365 SNNITCVTYHV-NIVLEEESTKDAQKTSWLVCNSVGGRGI--SSKLDSLADELKFVPIIG 421
Query: 1728 VAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMHPRENFEGRAFCFLPLP----I 1783
+A L+S +D A +F G+AFCFLPLP
Sbjct: 422 IAMPLSS---RDDEAKGA----------------------TSDFSGKAFCFLPLPPGEES 456
Query: 1784 STGLPAHVNAYFELSSNRRDI-WFGSDMTGGGRKRSDWNIYLLENVVAPAYGRL----LE 1838
STGLP H++ +F L+ NRR I W ++ + WN +L+ NVV AY L ++
Sbjct: 457 STGLPVHISGFFGLTDNRRSIKW--RELDQWRDPAALWNEFLVMNVVPKAYATLILDSIK 514
Query: 1839 KVALEIGPCY-----LFFSLWPKTLGLE-PWASVIRKLYQFVAEFNLRVLYTEARGGQWI 1892
++ +E + + + LWP+ ++ W V+ L+ + + V+Y+ + W+
Sbjct: 515 RLEMEKSSDFPLSVDVIYKLWPEASKVKVHWQPVLEPLFSELLQ--NAVIYSIS--CDWV 570
Query: 1893 STKHAIFP--DFSFPKADELIKALSGASLPVITLPQSLLERFMEICPS----LHFLKPKL 1946
+ F D + ++ L + + +P ++ S + + P
Sbjct: 571 RLEQVYFSELDENLEYTKTVLNYLQSSGKQIAKVPGNVDAAVQLTAASGTTPVRKVTPAW 630
Query: 1947 LRTLLIRRKREFKDRDAMILTLEYCLHDFEESMQFDTLGGLPLLPLADGSFTSIEMKGIG 2006
+R +L R+ + + LE+ L D + L GL LLPL +G+F
Sbjct: 631 VRQVL-RKCAHLGCAEEKLHLLEFVLSD----QAYSELLGLELLPLQNGNFVPFSSSVSD 685
Query: 2007 ERV-YIARGDEYGLLRDSIPHQLVDCVIPKEVHRKLCYIAQT---DSTNISFLSCQLLEK 2062
+ V YI + L S+ + + + + L AQT T + L+ + +
Sbjct: 686 QDVIYITSAEYPRSLFPSLEGRFILDNLKPHLVAALKEAAQTRGRPCTQLQLLNPERFAR 745
Query: 2063 LLVKLLPVEWQHASL-VSWTP--GIHGQPSLEWLQLLWNYLKAN-CDDLLMFSKWPILP- 2117
L+ +++ W L V W P PS+ WL+++W L + +DL +F + P++P
Sbjct: 746 LIKEVMNTFWPGRELIVQWYPFDENRNHPSVSWLKMVWKNLYIHFSEDLTLFDEMPLIPR 805
Query: 2118 ----VGDDC--LIQLK-PNLNVIKNDGWS---EKMSSLLVKVGCLFLRP-DLQLDHPKLE 2166
G C LI+L+ P+L ++ ++ + E ++ ++ K+G L+ D + HP ++
Sbjct: 806 TILEEGQTCVELIRLRIPSLVILDDESEAQLPEFLADIVQKLGGFVLKKLDASIQHPLIK 865
Query: 2167 CFVQSPTARGVLNV 2180
++ SP VL +
Sbjct: 866 KYIHSPLPSAVLQI 879
Score = 243 bits (620), Expect = 6e-62
Identities = 274/1033 (26%), Positives = 431/1033 (41%), Gaps = 166/1033 (16%)
Query: 843 KYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAED 902
K L +++P + +G E + ++ +L + + QF+ + F + E++AE
Sbjct: 2022 KNLCAVELPSSVKLGFE----EAGCKQILLENTFS-----EKQFFSEVFFPNIQEIEAEL 2072
Query: 903 RDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIG--TLKCPSVLYDPRNEEIYALLE 960
RD +M+ VL +++ S +LR IP + L PS L P + L +
Sbjct: 2073 RDPLMIFVLNE----KVDEFS--GVLRVTPCIPCSLEGHPLVLPSRLIHPEGR-VAKLFD 2125
Query: 961 DSDS-FPSGVFRESETLDIMRGL---GL-KTSVSPDTVLESARCIEHLMHEDQQKAYLKG 1015
D FP G ++ I+ L G+ K + D +LE A + + D A L+
Sbjct: 2126 IKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAVSVAEINKSDHVAACLRS 2185
Query: 1016 KVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCP 1075
+L S + D+K R K K+ Q I + P
Sbjct: 2186 SILLSLI------------DEK------------LKIRDPRAKDFAAKY----QTIRFLP 2217
Query: 1076 VLVSPPFHSLPWPVVSSMVAPPKVVRPPNDLW------LVSAGMRILDGE------CSST 1123
L P SL W S P+ + DL+ +V IL+ C S
Sbjct: 2218 FLTKPAGFSLDWKGNSFK---PETMFAATDLYTAEHQDIVCLLQPILNENSHSFRGCGSV 2274
Query: 1124 ALLY--CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSD 1181
+L LG + P ++ QL E+ K+ V D + + + Y L + +
Sbjct: 2275 SLAVKEFLGLLKKPTVDLVINQLKEVAKS---VDDGITLYQENITNA-CYKYLHEALMQN 2330
Query: 1182 EIEIVKAV--LEGCRWIWVGDGFATSDEVVLDGPLHLAPYIRVIPVDLAV-FKNLFLELG 1238
EI + + L+ +I V + + S++V APY+ +P F+ LF +G
Sbjct: 2331 EITKMSIIDKLKPFSFILVENAYVDSEKVSFHLNFEAAPYLYQLPNKYKNNFRELFETVG 2390
Query: 1239 IREFLQPSDYVNILFRMANKKGSSPLDTQEIR--------AVMLIVHHLAEVYLHGQKVQ 1290
+R+ D+ +L + ++G+ + + + + ++ + + +
Sbjct: 2391 VRQSCTVEDFALVLESIDQERGTKQITEENFQLCRRIISEGIWSLIREKKQEFCEKNYGK 2450
Query: 1291 LYLPDVSGRLFLAGDLVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDV 1350
+ LPD + L A L YND PW+ K T K+ H +I +V
Sbjct: 2451 ILLPDTNLMLLPAKSLCYNDCPWI------------------KVKDTTVKYCHADIPREV 2492
Query: 1351 AEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELV 1410
A KLG R L A ++ F G FGQ E LT+R+K IL Y L EL+
Sbjct: 2493 AVKLGAVPKRHKALERYASNVCFTTLGTE--FGQKEKLTSRIKSILNAYPSEKEMLKELL 2550
Query: 1411 QNAEDAGASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQE 1470
QNA+DA A+E+ F+ D Q+ + + A QGPAL +N+ FT D+ I +G+
Sbjct: 2551 QNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKG 2610
Query: 1471 SKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIV-MFDPHASNLPGISPSHPGLRIKFA 1529
+K + G++G+GFN VYH TD P F+SG +I+ +FDPHA PG + PG +
Sbjct: 2611 TKEGNPYKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSISPGRMFRDL 2670
Query: 1530 GRKILEQFPDQFSSLL--HFGCDLQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRS 1587
QF D L HF D T+FRFPLR A +A S+I + V++
Sbjct: 2671 DADFRTQFSDVLDLYLGTHFKLD-----NCTMFRFPLRNAEMAKVSEISSVPASDRMVQN 2725
Query: 1588 LFAAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFN 1647
L +E L+FL +++ ISI + + + +L+ V ++ D
Sbjct: 2726 LLDKLRSDGAELLMFLNHMEKISICEIDKSTGALNVLYSV-----------KGKITD--- 2771
Query: 1648 FFKEDRLVGMNRAQFLKKLSLSIDRDLPYKCQKILITEQGTHGRNSHYWIMTECLGGGNV 1707
DRL R QF + ID + K + +Q T Y + TE
Sbjct: 2772 ---GDRL---KRKQFHASV---IDSVTKKRQLKDIPVQQIT------YTMDTE------- 2809
Query: 1708 LKGTSEASTSNSHNFVPW-ACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMH 1766
+ N W C + +S++ V SA D LF +
Sbjct: 2810 ---------DSEGNLTTWLICNRSGFSSMEKVSKSVISAHKNQDI----TLFPRGGVAAC 2856
Query: 1767 PRENFE--GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYL 1824
N++ RAFCFLPL + TGLP HVN +F L S RR++W + G RSDWN L
Sbjct: 2857 ITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVG---VRSDWNNSL 2913
Query: 1825 LENVVAPAYGRLL 1837
+ ++APAY LL
Sbjct: 2914 MTALIAPAYVELL 2926
Score = 162 bits (410), Expect = 1e-37
Identities = 101/292 (34%), Positives = 167/292 (56%), Gaps = 22/292 (7%)
Query: 5 SPESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAG 64
+PE++ E GQ LT RI+ +L YP + + KEL+QNADDA AT S +D R +
Sbjct: 1445 NPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFLIDMRRNMD 1504
Query: 65 --DSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVY 122
++LL ++ GPAL ++N++ F++ DF++I+++G S K G+ K G+FG+GFNSVY
Sbjct: 1505 IRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRGEVDKVGKFGLGFNSVY 1564
Query: 123 HLTDLPSFVSGKYVVLFDPQGVYLPR--VSAANPGKRIDFT-GSSALSLYKDQFSPYC-A 178
H+TD+P +S +++++FDP ++ + +NPG +I+++ L + +QF P+
Sbjct: 1565 HITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRKFPNQFKPFIDV 1624
Query: 179 FGCDM----QSPFA--GTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTL 232
FGC + ++P++ GTLFR R +A S++S Y DI S+ + G +
Sbjct: 1625 FGCQLPLTVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLI 1684
Query: 233 LFLKSVLCIEMYVWDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNT 284
+F +SV MY+ K KI + S D I +++ SK+LNT
Sbjct: 1685 IFTQSVK--SMYL------KYLKIEETNPSLAQDTVIIKKKSC--SSKALNT 1726
Score = 74.7 bits (182), Expect = 4e-11
Identities = 43/153 (28%), Positives = 77/153 (50%), Gaps = 19/153 (12%)
Query: 363 GQAFCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPA 422
G+ FC+LPL ++TGL V +NG F V+SNR+ IW D R WN + ++ A
Sbjct: 1868 GEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTDTKGR-------WNTTFMRHVIVKA 1920
Query: 423 FVHMLHGVKELLGPTDI----YYSLWPTGSF-EEPWSILVQQIYINICNA-----PVIYS 472
++ +L +++L ++ YY++WP + +S++ Q Y +I + ++S
Sbjct: 1921 YLQVLSVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKELTKVFS 1980
Query: 473 NLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQL 505
+ G WVS D+ K +D+ A ++
Sbjct: 1981 D--GSTWVSMKNVRFLDDSILKRRDVGSAAFKI 2011
Score = 65.9 bits (159), Expect = 2e-08
Identities = 50/180 (27%), Positives = 85/180 (46%), Gaps = 26/180 (14%)
Query: 1773 GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYLLENVVAPA 1832
G FC+LPL I TGLP H+N F ++SNR++IW +D G WN + +V+ A
Sbjct: 1868 GEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIW-KTDTKG------RWNTTFMRHVIVKA 1920
Query: 1833 YGRLLEKVALEIGPC-----YLFFSLWP-KTLGLEPWASVIRKLYQFVAEFNLRVL-YTE 1885
Y ++L V ++ Y ++++WP L + ++ + + Y+ +A + L
Sbjct: 1921 YLQVL-SVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKELTKVF 1979
Query: 1886 ARGGQWISTKHAIFPDFSFPKADEL-----------IKALSGASLPVITLPQSLLERFME 1934
+ G W+S K+ F D S K ++ +K +L + LP S+ F E
Sbjct: 1980 SDGSTWVSMKNVRFLDDSILKRRDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKLGFEE 2039
>ref|NP_055178.2| sacsin [Homo sapiens]
Length = 4432
Score = 395 bits (1015), Expect = e-108
Identities = 439/1641 (26%), Positives = 717/1641 (42%), Gaps = 198/1641 (12%)
Query: 72 LSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFV 131
++ +QGPAL YN+AVFT +D+ I +I S K K GRFG+GFNSVYH+TD+P
Sbjct: 1 MAPYQGPALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIF 60
Query: 132 SGKYVVLFDP-QGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCA-FGCDMQS---- 185
SG + + DP Q ++ P S + D S +S DQF+P+ FG ++
Sbjct: 61 SGDQIGMLDPHQTLFGPHESGQCWNLKDD---SKEISELSDQFAPFVGIFGSTKETFING 117
Query: 186 PFAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYV 245
F GT FRFPLR S+LS Y + + +F + LLFLKSV + +YV
Sbjct: 118 NFPGTFFRFPLR----LQPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQDVSLYV 173
Query: 246 WDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVET 305
+A + V+S + H + + P +T V
Sbjct: 174 READGTEKLVFR---VTSSESKALKHERPNSIKILGTAISNYCKKTPSNNITCVTYHVNI 230
Query: 306 VRQVDRFYIVQ-TMASASSRIGSFAITASKEY---DIQLLPWASIAACIS---DNSLNND 358
V + + Q T + +G I++ + +++ +P IA +S D +
Sbjct: 231 VLEEESTKDAQKTSWLVCNSVGGRGISSKLDSLADELKFVPIIGIAMPLSSRDDEAKGAT 290
Query: 359 VLRTGQAFCFLPLPV----RTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLL 414
+G+AFCFLPLP TGL V ++GFF ++ NRR I + + +D+ ++WN L
Sbjct: 291 SDFSGKAFCFLPLPPGEESSTGLPVHISGFFGLTDNRRSIKWRE-LDQWRDPAALWNEFL 349
Query: 415 LEDLVAPAFVHM-LHGVKELLGP--------TDIYYSLWPTGS-FEEPWSILVQQIYINI 464
+ ++V A+ + L +K L D+ Y LWP S + W +++ ++ +
Sbjct: 350 VMNVVPKAYATLILDSIKRLEMEKSSDFPLSVDVIYKLWPEASKVKVHWQPVLEPLFSEL 409
Query: 465 CNAPVIYSNLGGGRWVSPSEAFLH--DEKFTKSKDLSLALMQLGMPVVHLPNSLFDMLLK 522
VIYS WV + + DE +K + L G + +P ++ D ++
Sbjct: 410 LQNAVIYSI--SCDWVRLEQVYFSELDENLEYTKTVLNYLQSSGKQIAKVPGNV-DAAVQ 466
Query: 523 YNSS------KVITPGTVRQFLRECESCNHLSRAH-KLLLLEYCLEDLVDDDVGKAAYNL 575
++ + +TP VRQ LR+C HL A KL LLE+ L D ++ L
Sbjct: 467 LTAASGTTPVRKVTPAWVRQVLRKCA---HLGCAEEKLHLLEFVLSDQAYSEL----LGL 519
Query: 576 PLLPLANGNFASFLEA--SKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAM 633
LLPL NGNF F + + + Y E L + R I ++ P+++ L A
Sbjct: 520 ELLPLQNGNFVPFSSSVSDQDVIYITSAEYPRSLFPSLEGRFILDNLKPHLVAALKEAAQ 579
Query: 634 SSN---TNIALFSIHHFAHLFPVFMPDDWKYK-CKVFWDP--DSCQKPTSSWFVLFWQYL 687
+ T + L + FA L M W + V W P ++ P+ SW + W+ L
Sbjct: 580 TRGRPCTQLQLLNPERFARLIKEVMNTFWPGRELIVQWYPFDENRNHPSVSWLKMVWKNL 639
Query: 688 GKQ-SEILPLFKDWPILPST---SGHLLRPSRQLKMINGSTLSDTVQ--------DILVK 735
SE L LF + P++P T G +L++ + L D + DI+ K
Sbjct: 640 YIHFSEDLTLFDEMPLIPRTILEEGQTCVELIRLRIPSLVILDDESEAQLPEFLADIVQK 699
Query: 736 IGCHILKP-GYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEERNELR 794
+G +LK ++HP + Y+ + VL+ + + + +SL+ ++ LR
Sbjct: 700 LGGFVLKKLDASIQHPLIKKYIHSPLPSAVLQIMEKM--PLQKLCNQITSLLPTHKDALR 757
Query: 795 RFLLDPQWYVGHSMDEFNIRFCRRLPIYQ-VYHREPTQDSQFSDLENPRKYLPPLDVPEF 853
+FL E R + L I++ + H S ++ L+ + +P
Sbjct: 758 KFLASLT-----DSSEKEKRIIQELAIFKRINHSSDQGISSYTKLKGCKVLHHTAKLPAD 812
Query: 854 ILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQA-EDRDSIMLSVLQ 912
+ + I ++ SS+ L+ +E++ K + D + E+ +ML VL+
Sbjct: 813 LRLSIS-VIDSSDEATIRLANMLKIEQLKTTSCLKLVLKDIENAFYSHEEVTQLMLWVLE 871
Query: 913 NLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALL--EDSDSFPSGVF 970
NL L E+ ++ + L LKFI + L+DP E + L E+ FP VF
Sbjct: 872 NLSSLKNENPNVLEWLTPLKFIQISQEQMVSAGELFDPDIEVLKDLFCNEEGTYFPPSVF 931
Query: 971 RESETLDIMRGLGLKT--SVSPDTVLESARCIEHLMH---EDQQKAYLKGKVLFSYLEVN 1025
+ L +R +GLK S+ V++ A+ IE L DQ K K L L N
Sbjct: 932 TSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEALQVGACPDQDVLLKKAKTLLLVLNKN 991
Query: 1026 ALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPVLVSPPFH-- 1083
T +S K ++K I W P P +
Sbjct: 992 H-----------------------TLLQSSEGKMTLKK-------IKWVPACKERPPNYP 1021
Query: 1084 -SLPWPV-VSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLGWMCPPGGGVIA 1141
SL W + ++ APP + + + L+ + + ++ E L LG P +
Sbjct: 1022 GSLVWKGDLCNLCAPPDMCDVGHAI-LIGSSLPLV--ESIHVNLEKALGIFTKPSLSAVL 1078
Query: 1142 A--QLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMI--GSDEIEIVKAVLEGCRWIW 1197
+++ +++ +D+ Q + + IY + + G D +K W+W
Sbjct: 1079 KHFKIVVDWYSSKTFSDEDYYQFQHILL-EIYGFMHDHLNEGKDSFRALKFP-----WVW 1132
Query: 1198 VGDGFATSDEVVLDGPLH---LAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFR 1254
G F + V+ P+H L PY+ +P +A F LF G E L SD+++++ +
Sbjct: 1133 TGKKFCPLAQAVIK-PIHDLDLQPYLHNVPKTMAKFHQLFKVCGSIEELT-SDHISMVIQ 1190
Query: 1255 MANKKGSSPLDTQEIRAVMLIVHHLAEVYLHGQ-------KVQLYLPDVSGRLFLAG--- 1304
K L QE + + ++ ++ Q V ++ +L +
Sbjct: 1191 KIYLKSDQDLSEQESKQNLHLMLNIIRWLYSNQIPASPNTPVPIHHSKNPSKLIMKPIHE 1250
Query: 1305 ----DLVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLR 1360
D+ +D LL ED P + VH +I AE L V L
Sbjct: 1251 CCYCDIKVDDLNDLL--ED-----SVEPII----------LVHEDIPMKTAEWLKVPCLS 1293
Query: 1361 RMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASE 1420
L+ + ++M F E GQ E LT R+K+ILE Y EL+QNA+DA A+E
Sbjct: 1294 TRLI--NPENMGF------EQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATE 1345
Query: 1421 VIFLLD--KSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFA 1478
FL+D ++ ++L P MA GPAL+ FN+S F+ D I+R+G+ K +
Sbjct: 1346 CSFLIDMRRNMDIRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRGEVDK 1405
Query: 1479 IGRFGLGFNCVYHFTDIPMFVSGENIVMFDPHASNLPG--ISPSHPGLRIKFA-GRKILE 1535
+G+FGLGFN VYH TDIP+ +S E ++MFDP+ +++ S+PG++I ++ +K L
Sbjct: 1406 VGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLR 1465
Query: 1536 QFPDQFSSLLH-FGCDL------QHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSL 1588
+FP+QF + FGC L + + GTLFR RT A S++ Y D+ SL
Sbjct: 1466 KFPNQFKPFIDVFGCQLPLTVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSL 1525
Query: 1589 FAAFSEVVSETLLFLRNVKSI 1609
FS ++F ++VKS+
Sbjct: 1526 VDEFSLCGHRLIIFTQSVKSM 1546
Score = 291 bits (744), Expect = 2e-76
Identities = 349/1460 (23%), Positives = 589/1460 (39%), Gaps = 212/1460 (14%)
Query: 13 DFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
+FGQ LT RI+ +L YP +LKEL+QNADDA AT + D R H D +
Sbjct: 2374 EFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKW 2433
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+ QGPAL YN+ FTEDD I +G +K G KTG++G+GFNSVYH+TD PSF+S
Sbjct: 2434 APLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPYKTGQYGIGFNSVYHITDCPSFIS 2493
Query: 133 GKYVV-LFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTL 191
G ++ +FDP Y P ++ +PG+ + + + D Y + + T+
Sbjct: 2494 GNDILCIFDPHARYAPGATSISPGRMFRDLDADFRTQFSDVLDLYLGTHFKLDNC---TM 2550
Query: 192 FRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEP 251
FRFPLRNA+ A S++S + + ++ +L +G L+FL + I + D
Sbjct: 2551 FRFPLRNAEMAKVSEISSVPASDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKSTG 2610
Query: 252 KPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVRQVDR 311
++S D + +Q + S+ ++ P++ +T + ++ +
Sbjct: 2611 ALNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTT 2670
Query: 312 FYIVQTMA-SASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTGQAFCFLP 370
+ I S+ ++ I+A K DI L P +AACI+ N + +AFCFLP
Sbjct: 2671 WLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACITHN-----YKKPHRAFCFLP 2725
Query: 371 LPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHM---- 426
L + TGL VNG F + S RR +W D+ VRS WN L+ L+APA+V +
Sbjct: 2726 LSLETGLPFHVNGHFALDSARRNLWRDDN---GVGVRSDWNNSLMTALIAPAYVELLIQL 2782
Query: 427 -------------------LHGVKELLGPTDIYYSLWPTGSFEEPWSI--LVQQIYINIC 465
+H VK+ L + S +P + + LV+ +Y I
Sbjct: 2783 KKRYFPGSDPTLSVLQNTPIHVVKDTLKK---FLSFFPVNRLDLQPDLYCLVKALYNCIH 2839
Query: 466 N-----APVIYS-NLGGG--------RWVSPSEA---------FLHDE-KFTKSKDLSLA 501
PV+ + N+ G W++ S + L DE + K+ D ++
Sbjct: 2840 EDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTRPFFDNLLQDELQHLKNADYNIT 2899
Query: 502 ---------------LMQLGMPVVHLPN---SLFDMLLKYNSS-KVITPGTVRQFLRECE 542
L+++G +V+ + +L+ L+ + +TP +R FL
Sbjct: 2900 TRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLIDADIPVSYVTPADIRSFLMTFS 2959
Query: 543 S----CN-----------HLSRAHKL-LLLEYCLEDLVDDDVGKAAYNLPLLPLANGNFA 586
S C+ +L H L LL++YC +D ++++ LPLL +
Sbjct: 2960 SPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEENEI--EVEGLPLLITLDSVLQ 3017
Query: 587 SFLEASKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSNTNIA-LFSIH 645
+F +A + P F+ ++L+ D ++ + + S I + N +A +F I
Sbjct: 3018 TF-DAKR--PKFLTTY--HELIPSRKDLFMN-----TLYLKYSNILL--NCKVAKVFDIS 3065
Query: 646 HFAHLFPVFMPDDWKYKCKVFWDPDSCQKPTSSWFVLFWQYLGK-------QSEILPLF- 697
FA L +P ++K K W + + SW W ++ + Q E P F
Sbjct: 3066 SFADLLSSVLPREYKTKSCTKWKDNFASE---SWLKNAWHFISESVSVKEDQEETKPTFD 3122
Query: 698 ------KDWPILPST------------SGHLLRPSRQLKM-INGSTLSDTVQDILVKIGC 738
KDW +LP T G +L P + + + + SD V L+K GC
Sbjct: 3123 IVVDTLKDWALLPGTKFTVSANQLVVPEGDVLLPLSLMHIAVFPNAQSDKVFHALMKAGC 3182
Query: 739 HILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEE--RNELRRF 796
L + F L + A + + A + V S+ AE+ N+
Sbjct: 3183 IQLALNKICSKDSAFVPLLSCHTANIESP--TSILKALHYMVQTSTFRAEKLVENDFEAL 3240
Query: 797 LLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKYLPPLDVPEFILV 856
L+ + H M + +I+ + LP Y+ +F K +P +V ++
Sbjct: 3241 LMYFNCNLNHLMSQDDIKILKSLPCYKSISGRYVSIGKFGTCYVLTKSIPSAEVEKWTQS 3300
Query: 857 GIE-FIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSIMLSV---LQ 912
F+ + +E L G + + Y KH+ ++ L + + ++ + L
Sbjct: 3301 SSSAFLEEKIHLKE--LYEVIGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLS 3358
Query: 913 NLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLEDSDSFPSGVFRE 972
+ LS + + L +L I LK YD +L + P+ F++
Sbjct: 3359 SAEELSEIKEQLFEKLESLLIIHDANSRLKQAKHFYDRTVRVFEVMLPEKLFIPNDFFKK 3418
Query: 973 SETL--------------DIMRGLGLKTSVSPDTVLESARCIE-HLMHEDQQKAYLKGKV 1017
E L + +R +GLK +S +L+ A+ I E+ K L+ V
Sbjct: 3419 LEQLIKPKNHVTFMTSWVEFLRNIGLKYILSQQQLLQFAKEISVRANTENWSKETLQNTV 3478
Query: 1018 --LFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCP 1075
L ++ + L F + + + + A A R ++ L LI +
Sbjct: 3479 DILLHHIFQERMDLLSGNFLKELSLIPFLCPERAPAEFIR-FHPQYQEVNGTLPLIKFNG 3537
Query: 1076 VLVSPPFH-----SLPW---PVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLY 1127
V+P F L W P++ P + G + E L
Sbjct: 3538 AQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKE--------QEGSDLGPQEQLEQVLNM 3589
Query: 1128 CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVK 1187
+ PP VI I L +E+ ++ + + +++ E +
Sbjct: 3590 LNVNLDPPLDKVI-------NNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREF-R 3641
Query: 1188 AVLEGCRWIWVGDGF--ATSDEVV--LDGPLHLAPYIRVIPVDLAVFKNLFLELGIREFL 1243
L G ++ V DG+ +EVV L+ PY+ +P++L F LF LG + +
Sbjct: 3642 FQLRGVAFVMVEDGWKLLKPEEVVINLEYESDFKPYLYKLPLELGTFHQLFKHLGTEDII 3701
Query: 1244 QPSDYVNILFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYLHG-----------QKVQLY 1292
YV +L R+ LD E+R V +V L + + + LY
Sbjct: 3702 STKQYVEVLSRIFKNSEGKQLDPNEMRTVKRVVSGLFRSLQNDSVKVRSDLENVRDLALY 3761
Query: 1293 LPDVSGRLFLAGDLVYNDAP 1312
LP GRL + LV++DAP
Sbjct: 3762 LPSQDGRLVKSSILVFDDAP 3781
Score = 243 bits (620), Expect = 6e-62
Identities = 274/1033 (26%), Positives = 431/1033 (41%), Gaps = 166/1033 (16%)
Query: 843 KYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAED 902
K L +++P + +G E + ++ +L + + QF+ + F + E++AE
Sbjct: 1875 KNLCAVELPSSVKLGFE----EAGCKQILLENTFS-----EKQFFSEVFFPNIQEIEAEL 1925
Query: 903 RDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIG--TLKCPSVLYDPRNEEIYALLE 960
RD +M+ VL +++ S +LR IP + L PS L P + L +
Sbjct: 1926 RDPLMIFVLNE----KVDEFS--GVLRVTPCIPCSLEGHPLVLPSRLIHPEGR-VAKLFD 1978
Query: 961 DSDS-FPSGVFRESETLDIMRGL---GL-KTSVSPDTVLESARCIEHLMHEDQQKAYLKG 1015
D FP G ++ I+ L G+ K + D +LE A + + D A L+
Sbjct: 1979 IKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAVSVAEINKSDHVAACLRS 2038
Query: 1016 KVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCP 1075
+L S + D+K R K K+ Q I + P
Sbjct: 2039 SILLSLI------------DEK------------LKIRDPRAKDFAAKY----QTIRFLP 2070
Query: 1076 VLVSPPFHSLPWPVVSSMVAPPKVVRPPNDLW------LVSAGMRILDGE------CSST 1123
L P SL W S P+ + DL+ +V IL+ C S
Sbjct: 2071 FLTKPAGFSLDWKGNSFK---PETMFAATDLYTAEHQDIVCLLQPILNENSHSFRGCGSV 2127
Query: 1124 ALLY--CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSD 1181
+L LG + P ++ QL E+ K+ V D + + + Y L + +
Sbjct: 2128 SLAVKEFLGLLKKPTVDLVINQLKEVAKS---VDDGITLYQENITNA-CYKYLHEALMQN 2183
Query: 1182 EIEIVKAV--LEGCRWIWVGDGFATSDEVVLDGPLHLAPYIRVIPVDLAV-FKNLFLELG 1238
EI + + L+ +I V + + S++V APY+ +P F+ LF +G
Sbjct: 2184 EITKMSIIDKLKPFSFILVENAYVDSEKVSFHLNFEAAPYLYQLPNKYKNNFRELFETVG 2243
Query: 1239 IREFLQPSDYVNILFRMANKKGSSPLDTQEIR--------AVMLIVHHLAEVYLHGQKVQ 1290
+R+ D+ +L + ++G+ + + + + ++ + + +
Sbjct: 2244 VRQSCTVEDFALVLESIDQERGTKQITEENFQLCRRIISEGIWSLIREKKQEFCEKNYGK 2303
Query: 1291 LYLPDVSGRLFLAGDLVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDV 1350
+ LPD + L A L YND PW+ K T K+ H +I +V
Sbjct: 2304 ILLPDTNLMLLPAKSLCYNDCPWI------------------KVKDTTVKYCHADIPREV 2345
Query: 1351 AEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELV 1410
A KLG R L A ++ F G FGQ E LT+R+K IL Y L EL+
Sbjct: 2346 AVKLGAVPKRHKALERYASNVCFTTLGTE--FGQKEKLTSRIKSILNAYPSEKEMLKELL 2403
Query: 1411 QNAEDAGASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQE 1470
QNA+DA A+E+ F+ D Q+ + + A QGPAL +N+ FT D+ I +G+
Sbjct: 2404 QNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKG 2463
Query: 1471 SKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIV-MFDPHASNLPGISPSHPGLRIKFA 1529
+K + G++G+GFN VYH TD P F+SG +I+ +FDPHA PG + PG +
Sbjct: 2464 TKEGNPYKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSISPGRMFRDL 2523
Query: 1530 GRKILEQFPDQFSSLL--HFGCDLQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRS 1587
QF D L HF D T+FRFPLR A +A S+I + V++
Sbjct: 2524 DADFRTQFSDVLDLYLGTHFKLD-----NCTMFRFPLRNAEMAKVSEISSVPASDRMVQN 2578
Query: 1588 LFAAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFN 1647
L +E L+FL +++ ISI + + + +L+ V ++ D
Sbjct: 2579 LLDKLRSDGAELLMFLNHMEKISICEIDKSTGALNVLYSV-----------KGKITD--- 2624
Query: 1648 FFKEDRLVGMNRAQFLKKLSLSIDRDLPYKCQKILITEQGTHGRNSHYWIMTECLGGGNV 1707
DRL R QF + ID + K + +Q T Y + TE
Sbjct: 2625 ---GDRL---KRKQFHASV---IDSVTKKRQLKDIPVQQIT------YTMDTE------- 2662
Query: 1708 LKGTSEASTSNSHNFVPW-ACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMH 1766
+ N W C + +S++ V SA D LF +
Sbjct: 2663 ---------DSEGNLTTWLICNRSGFSSMEKVSKSVISAHKNQDI----TLFPRGGVAAC 2709
Query: 1767 PRENFE--GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYL 1824
N++ RAFCFLPL + TGLP HVN +F L S RR++W + G RSDWN L
Sbjct: 2710 ITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVG---VRSDWNNSL 2766
Query: 1825 LENVVAPAYGRLL 1837
+ ++APAY LL
Sbjct: 2767 MTALIAPAYVELL 2779
Score = 215 bits (547), Expect = 2e-53
Identities = 209/787 (26%), Positives = 360/787 (45%), Gaps = 101/787 (12%)
Query: 1440 MADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFV 1499
MA +QGPALY +N++VFTP+D + I I + K + +GRFG+GFN VYH TD+P
Sbjct: 1 MAPYQGPALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIF 60
Query: 1500 SGENIVMFDPHASNLPGISPSHPGLRIKFAGRKILEQFPDQFSSLLH-FGCD----LQHP 1554
SG+ I M DPH L G S +K ++I E DQF+ + FG +
Sbjct: 61 SGDQIGMLDPH-QTLFGPHESGQCWNLKDDSKEISE-LSDQFAPFVGIFGSTKETFINGN 118
Query: 1555 FPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISIFLK 1614
FPGT FRFPLR SQ+ +Y + V LF +F LLFL++V+ +S++++
Sbjct: 119 FPGTFFRFPLR----LQPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQDVSLYVR 174
Query: 1615 EGTGHEMRLLHRVSRASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLSLSIDRDL 1674
E G E +L+ RV+ + ES+ E + +++G + + KK + +
Sbjct: 175 EADGTE-KLVFRVTSS---ESKALKHERPNSI------KILGTAISNYCKKTPSNNITCV 224
Query: 1675 PYKCQKILITEQGTHGRNSHYWIMTECLGGGNVLKGTSEASTSNSHNFVPWACVAAYLNS 1734
Y I++ E+ T W++ +GG + + S ++ FVP +A L+S
Sbjct: 225 TYHV-NIVLEEESTKDAQKTSWLVCNSVGGRGI--SSKLDSLADELKFVPIIGIAMPLSS 281
Query: 1735 VKHGEDLVDSAEVEDDCLVSSDLFQFASLPMHPRENFEGRAFCFLPLP----ISTGLPAH 1790
+D A +F G+AFCFLPLP STGLP H
Sbjct: 282 ---RDDEAKGA----------------------TSDFSGKAFCFLPLPPGEESSTGLPVH 316
Query: 1791 VNAYFELSSNRRDI-WFGSDMTGGGRKRSDWNIYLLENVVAPAYGRL----LEKVALEIG 1845
++ +F L+ NRR I W ++ + WN +L+ NVV AY L ++++ +E
Sbjct: 317 ISGFFGLTDNRRSIKW--RELDQWRDPAALWNEFLVMNVVPKAYATLILDSIKRLEMEKS 374
Query: 1846 PCY-----LFFSLWPKTLGLE-PWASVIRKLYQFVAEFNLRVLYTEARGGQWISTKHAIF 1899
+ + + LWP+ ++ W V+ L+ + + V+Y+ + W+ + F
Sbjct: 375 SDFPLSVDVIYKLWPEASKVKVHWQPVLEPLFSELLQ--NAVIYSIS--CDWVRLEQVYF 430
Query: 1900 P--DFSFPKADELIKALSGASLPVITLPQSLLERFMEICPS----LHFLKPKLLRTLLIR 1953
D + ++ L + + +P ++ S + + P +R +L R
Sbjct: 431 SELDENLEYTKTVLNYLQSSGKQIAKVPGNVDAAVQLTAASGTTPVRKVTPAWVRQVL-R 489
Query: 1954 RKREFKDRDAMILTLEYCLHDFEESMQFDTLGGLPLLPLADGSFTSIEMKGIGERV-YIA 2012
+ + + LE+ L D + L GL LLPL +G+F + V YI
Sbjct: 490 KCAHLGCAEEKLHLLEFVLSD----QAYSELLGLELLPLQNGNFVPFSSSVSDQDVIYIT 545
Query: 2013 RGDEYGLLRDSIPHQLVDCVIPKEVHRKLCYIAQT---DSTNISFLSCQLLEKLLVKLLP 2069
+ L S+ + + + + L AQT T + L+ + +L+ +++
Sbjct: 546 SAEYPRSLFPSLEGRFILDNLKPHLVAALKEAAQTRGRPCTQLQLLNPERFARLIKEVMN 605
Query: 2070 VEWQHASL-VSWTP--GIHGQPSLEWLQLLWNYLKAN-CDDLLMFSKWPILP-----VGD 2120
W L V W P PS+ WL+++W L + +DL +F + P++P G
Sbjct: 606 TFWPGRELIVQWYPFDENRNHPSVSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTILEEGQ 665
Query: 2121 DC--LIQLK-PNLNVIKNDGWS---EKMSSLLVKVGCLFLRP-DLQLDHPKLECFVQSPT 2173
C LI+L+ P+L ++ ++ + E ++ ++ K+G L+ D + HP ++ ++ SP
Sbjct: 666 TCVELIRLRIPSLVILDDESEAQLPEFLADIVQKLGGFVLKKLDASIQHPLIKKYIHSPL 725
Query: 2174 ARGVLNV 2180
VL +
Sbjct: 726 PSAVLQI 732
Score = 162 bits (410), Expect = 1e-37
Identities = 101/292 (34%), Positives = 167/292 (56%), Gaps = 22/292 (7%)
Query: 5 SPESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAG 64
+PE++ E GQ LT RI+ +L YP + + KEL+QNADDA AT S +D R +
Sbjct: 1298 NPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFLIDMRRNMD 1357
Query: 65 --DSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVY 122
++LL ++ GPAL ++N++ F++ DF++I+++G S K G+ K G+FG+GFNSVY
Sbjct: 1358 IRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRGEVDKVGKFGLGFNSVY 1417
Query: 123 HLTDLPSFVSGKYVVLFDPQGVYLPR--VSAANPGKRIDFT-GSSALSLYKDQFSPYC-A 178
H+TD+P +S +++++FDP ++ + +NPG +I+++ L + +QF P+
Sbjct: 1418 HITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRKFPNQFKPFIDV 1477
Query: 179 FGCDM----QSPFA--GTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTL 232
FGC + ++P++ GTLFR R +A S++S Y DI S+ + G +
Sbjct: 1478 FGCQLPLTVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLI 1537
Query: 233 LFLKSVLCIEMYVWDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNT 284
+F +SV MY+ K KI + S D I +++ SK+LNT
Sbjct: 1538 IFTQSVK--SMYL------KYLKIEETNPSLAQDTVIIKKKSC--SSKALNT 1579
Score = 74.7 bits (182), Expect = 4e-11
Identities = 43/153 (28%), Positives = 77/153 (50%), Gaps = 19/153 (12%)
Query: 363 GQAFCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPA 422
G+ FC+LPL ++TGL V +NG F V+SNR+ IW D R WN + ++ A
Sbjct: 1721 GEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTDTKGR-------WNTTFMRHVIVKA 1773
Query: 423 FVHMLHGVKELLGPTDI----YYSLWPTGSF-EEPWSILVQQIYINICNA-----PVIYS 472
++ +L +++L ++ YY++WP + +S++ Q Y +I + ++S
Sbjct: 1774 YLQVLSVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKELTKVFS 1833
Query: 473 NLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQL 505
+ G WVS D+ K +D+ A ++
Sbjct: 1834 D--GSTWVSMKNVRFLDDSILKRRDVGSAAFKI 1864
Score = 65.9 bits (159), Expect = 2e-08
Identities = 50/180 (27%), Positives = 85/180 (46%), Gaps = 26/180 (14%)
Query: 1773 GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYLLENVVAPA 1832
G FC+LPL I TGLP H+N F ++SNR++IW +D G WN + +V+ A
Sbjct: 1721 GEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIW-KTDTKG------RWNTTFMRHVIVKA 1773
Query: 1833 YGRLLEKVALEIGPC-----YLFFSLWP-KTLGLEPWASVIRKLYQFVAEFNLRVL-YTE 1885
Y ++L V ++ Y ++++WP L + ++ + + Y+ +A + L
Sbjct: 1774 YLQVL-SVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKELTKVF 1832
Query: 1886 ARGGQWISTKHAIFPDFSFPKADEL-----------IKALSGASLPVITLPQSLLERFME 1934
+ G W+S K+ F D S K ++ +K +L + LP S+ F E
Sbjct: 1833 SDGSTWVSMKNVRFLDDSILKRRDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKLGFEE 1892
>emb|CAH18265.1| hypothetical protein [Homo sapiens]
Length = 2015
Score = 305 bits (780), Expect = 2e-80
Identities = 352/1338 (26%), Positives = 583/1338 (43%), Gaps = 175/1338 (13%)
Query: 362 TGQAFCFLPLPV----RTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLED 417
+G+AFCFLPLP TGL V ++GFF ++ NRR I + + +D+ ++WN L+ +
Sbjct: 18 SGKAFCFLPLPPGEESSTGLPVHISGFFGLTDNRRSIKWRE-LDQWRDPAALWNEFLVMN 76
Query: 418 LVAPAFVHM-LHGVKELLGP--------TDIYYSLWPTGS-FEEPWSILVQQIYINICNA 467
+V A+ + L +K L D+ Y LWP S + W +++ ++ +
Sbjct: 77 VVPKAYATLILDSIKRLEMEKSSDFPLSVDVIYKLWPEASKVKVHWQPVLEPLFSELLQN 136
Query: 468 PVIYSNLGGGRWVSPSEAFLH--DEKFTKSKDLSLALMQLGMPVVHLPNSLFDMLLKYNS 525
VIYS WV + + DE +K + L G + +P ++ D ++ +
Sbjct: 137 AVIYSI--SCDWVRLEQVYFSELDENLEYTKTVLNYLQSSGKQIAKVPGNV-DAAVQLTA 193
Query: 526 S------KVITPGTVRQFLRECESCNHLSRAH-KLLLLEYCLEDLVDDDVGKAAYNLPLL 578
+ + +TP VRQ LR+C HL A KL LLE+ L D ++ L LL
Sbjct: 194 ASGTTPVRKVTPAWVRQVLRKCA---HLGCAEEKLHLLEFVLSDQAYSEL----LGLELL 246
Query: 579 PLANGNFASFLEA--SKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSN 636
PL NGNF F + + + Y E L + R I ++ P+++ L A +
Sbjct: 247 PLQNGNFVPFSSSVSDQDVIYITSAEYPRSLFPSLEGRFILDNLKPHLVAALKEAAQTRG 306
Query: 637 ---TNIALFSIHHFAHLFPVFMPDDWKYK-CKVFWDP--DSCQKPTSSWFVLFWQYLGKQ 690
T + L + FA L M W + V W P ++ P+ SW + W+ L
Sbjct: 307 RPCTQLQLLNPERFARLIKEVMNTFWPGRELIVQWYPFDENRNHPSVSWLKMVWKNLYIH 366
Query: 691 -SEILPLFKDWPILPST---SGHLLRPSRQLKMINGSTLSDTVQ--------DILVKIGC 738
SE L LF + P++P T G +L++ + L D + DI+ K+G
Sbjct: 367 FSEDLTLFDEMPLIPRTILEEGQTCVELIRLRIPSLVILDDESEAQLPEFLADIVQKLGG 426
Query: 739 HILKP-GYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEERNELRRFL 797
+LK ++HP + Y+ + VL+ + + + +SL+ ++ LR+FL
Sbjct: 427 FVLKKLDASIQHPLIKKYIHSPLPSAVLQIMEKM--PLQKLCNQITSLLPTHKDALRKFL 484
Query: 798 LDPQWYVGHSMDEFNIRFCRRLPIYQ-VYHREPTQDSQFSDLENPRKYLPPLDVPEFILV 856
E R + L I++ + H S ++ L+ + +P + +
Sbjct: 485 ASLT-----DSSEKEKRIIQELAIFKRINHSSDQGISSYTKLKGCKVLHHTAKLPADLRL 539
Query: 857 GIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQA-EDRDSIMLSVLQNLP 915
I ++ SS+ L+ +E++ K + D + E+ +ML VL+NL
Sbjct: 540 SIS-VIDSSDEATIRLANMLKIEQLKTTSCLKLVLKDIENAFYSHEEVTQLMLWVLENLS 598
Query: 916 LLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALL--EDSDSFPSGVFRES 973
L E+ ++ + L LKFI + L+DP E + L E+ FP VF
Sbjct: 599 SLKNENPNVLEWLTPLKFIQISQEQMVSAGELFDPDIEVLKDLFCNEEGTYFPPSVFTSP 658
Query: 974 ETLDIMRGLGLKT--SVSPDTVLESARCIEHLMH---EDQQKAYLKGKVLFSYLEVNALK 1028
+ L +R +GLK S+ V++ A+ IE L DQ K K L L N
Sbjct: 659 DILHSLRQIGLKNEASLKEKDVVQVAKKIEALQVGACPDQDVLLKKAKTLLLVLNKNH-- 716
Query: 1029 WLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPVLVSPPFH---SL 1085
T +S K ++K I W P P + SL
Sbjct: 717 ---------------------TLLQSSEGKMTLKK-------IKWVPACKERPPNYPGSL 748
Query: 1086 PWPV-VSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLGWMCPPGGGVIAA-- 1142
W + ++ APP + + + L+ + + ++ E L LG P +
Sbjct: 749 VWKGDLCNLCAPPDMCDVGHAI-LIGSSLPLV--ESIHVNLEKALGIFTKPSLSAVLKHF 805
Query: 1143 QLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMI--GSDEIEIVKAVLEGCRWIWVGD 1200
+++ +++ +D+ Q + + IY + + G D +K W+W G
Sbjct: 806 KIVVDWYSSKTFSDEDYYQFQHILL-EIYGFMHDHLNEGKDSFRALKFP-----WVWTGK 859
Query: 1201 GFATSDEVVLDGPLH---LAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFRMAN 1257
F + V+ P+H L PY+ +P +A F LF G E L SD+++++ +
Sbjct: 860 KFCPLAQAVIK-PIHDLDLQPYLHNVPKTMAKFHQLFKVCGSIEELT-SDHISMVIQKIY 917
Query: 1258 KKGSSPLDTQEIRAVMLIVHHLAEVYLHGQ-------KVQLYLPDVSGRLFLAG------ 1304
K L QE + + ++ ++ Q V ++ +L +
Sbjct: 918 LKSDQDLSEQESKQNLHLMLNIIRWLYSNQIPASPNTPVPIHHSKNPSKLIMKPIHECCY 977
Query: 1305 -DLVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRRML 1363
D+ +D LL ED P + VH +I AE L V L L
Sbjct: 978 CDIKVDDLNDLL--ED-----SVEPII----------LVHEDIPMKTAEWLKVPCLSTRL 1020
Query: 1364 LAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIF 1423
+ + ++M F E GQ E LT R+K+ILE Y EL+QNA+DA A+E F
Sbjct: 1021 I--NPENMGF------EQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSF 1072
Query: 1424 LLD--KSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGR 1481
L+D ++ ++L P MA GPAL+ FN+S F+ D I+R+G+ K + +G+
Sbjct: 1073 LIDMRRNMDIRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRGEVDKVGK 1132
Query: 1482 FGLGFNCVYHFTDIPMFVSGENIVMFDPHASNLPG--ISPSHPGLRIKFA-GRKILEQFP 1538
FGLGFN VYH TDIP+ +S E ++MFDP+ +++ S+PG++I ++ +K L +FP
Sbjct: 1133 FGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRKFP 1192
Query: 1539 DQFSSLLH-FGCDL------QHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAA 1591
+QF + FGC L + + GTLFR RT A S++ Y D+ SL
Sbjct: 1193 NQFKPFIDVFGCQLPLTVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDE 1252
Query: 1592 FSEVVSETLLFLRNVKSI 1609
FS ++F ++VKS+
Sbjct: 1253 FSLCGHRLIIFTQSVKSM 1270
Score = 162 bits (410), Expect = 1e-37
Identities = 101/292 (34%), Positives = 167/292 (56%), Gaps = 22/292 (7%)
Query: 5 SPESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAG 64
+PE++ E GQ LT RI+ +L YP + + KEL+QNADDA AT S +D R +
Sbjct: 1022 NPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFLIDMRRNMD 1081
Query: 65 --DSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVY 122
++LL ++ GPAL ++N++ F++ DF++I+++G S K G+ K G+FG+GFNSVY
Sbjct: 1082 IRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRGEVDKVGKFGLGFNSVY 1141
Query: 123 HLTDLPSFVSGKYVVLFDPQGVYLPR--VSAANPGKRIDFT-GSSALSLYKDQFSPYC-A 178
H+TD+P +S +++++FDP ++ + +NPG +I+++ L + +QF P+
Sbjct: 1142 HITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRKFPNQFKPFIDV 1201
Query: 179 FGCDM----QSPFA--GTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTL 232
FGC + ++P++ GTLFR R +A S++S Y DI S+ + G +
Sbjct: 1202 FGCQLPLTVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLI 1261
Query: 233 LFLKSVLCIEMYVWDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNT 284
+F +SV MY+ K KI + S D I +++ SK+LNT
Sbjct: 1262 IFTQSVK--SMYL------KYLKIEETNPSLAQDTVIIKKKSC--SSKALNT 1303
Score = 101 bits (251), Expect = 4e-19
Identities = 110/452 (24%), Positives = 205/452 (45%), Gaps = 52/452 (11%)
Query: 1770 NFEGRAFCFLPLP----ISTGLPAHVNAYFELSSNRRDI-WFGSDMTGGGRKRSDWNIYL 1824
+F G+AFCFLPLP STGLP H++ +F L+ NRR I W ++ + WN +L
Sbjct: 16 DFSGKAFCFLPLPPGEESSTGLPVHISGFFGLTDNRRSIKW--RELDQWRDPAALWNEFL 73
Query: 1825 LENVVAPAYGRL----LEKVALEIGPCY-----LFFSLWPKTLGLE-PWASVIRKLYQFV 1874
+ NVV AY L ++++ +E + + + LWP+ ++ W V+ L+ +
Sbjct: 74 VMNVVPKAYATLILDSIKRLEMEKSSDFPLSVDVIYKLWPEASKVKVHWQPVLEPLFSEL 133
Query: 1875 AEFNLRVLYTEARGGQWISTKHAIFP--DFSFPKADELIKALSGASLPVITLPQSLLERF 1932
+ V+Y+ + W+ + F D + ++ L + + +P ++
Sbjct: 134 LQ--NAVIYSIS--CDWVRLEQVYFSELDENLEYTKTVLNYLQSSGKQIAKVPGNVDAAV 189
Query: 1933 MEICPS----LHFLKPKLLRTLLIRRKREFKDRDAMILTLEYCLHDFEESMQFDTLGGLP 1988
S + + P +R +L R+ + + LE+ L D + L GL
Sbjct: 190 QLTAASGTTPVRKVTPAWVRQVL-RKCAHLGCAEEKLHLLEFVLSD----QAYSELLGLE 244
Query: 1989 LLPLADGSFTSIEMKGIGERV-YIARGDEYGLLRDSIPHQLVDCVIPKEVHRKLCYIAQT 2047
LLPL +G+F + V YI + L S+ + + + + L AQT
Sbjct: 245 LLPLQNGNFVPFSSSVSDQDVIYITSAEYPRSLFPSLEGRFILDNLKPHLVAALKEAAQT 304
Query: 2048 ---DSTNISFLSCQLLEKLLVKLLPVEWQHASL-VSWTP--GIHGQPSLEWLQLLWNYLK 2101
T + L+ + +L+ +++ W L V W P PS+ WL+++W L
Sbjct: 305 RGRPCTQLQLLNPERFARLIKEVMNTFWPGRELIVQWYPFDENRNHPSVSWLKMVWKNLY 364
Query: 2102 AN-CDDLLMFSKWPILP-----VGDDC--LIQLK-PNLNVIKNDGWS---EKMSSLLVKV 2149
+ +DL +F + P++P G C LI+L+ P+L ++ ++ + E ++ ++ K+
Sbjct: 365 IHFSEDLTLFDEMPLIPRTILEEGQTCVELIRLRIPSLVILDDESEAQLPEFLADIVQKL 424
Query: 2150 GCLFLRP-DLQLDHPKLECFVQSPTARGVLNV 2180
G L+ D + HP ++ ++ SP VL +
Sbjct: 425 GGFVLKKLDASIQHPLIKKYIHSPLPSAVLQI 456
Score = 74.7 bits (182), Expect = 4e-11
Identities = 43/153 (28%), Positives = 77/153 (50%), Gaps = 19/153 (12%)
Query: 363 GQAFCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPA 422
G+ FC+LPL ++TGL V +NG F V+SNR+ IW D R WN + ++ A
Sbjct: 1445 GEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTDTKGR-------WNTTFMRHVIVKA 1497
Query: 423 FVHMLHGVKELLGPTDI----YYSLWPTGSF-EEPWSILVQQIYINICNA-----PVIYS 472
++ +L +++L ++ YY++WP + +S++ Q Y +I + ++S
Sbjct: 1498 YLQVLSVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKELTKVFS 1557
Query: 473 NLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQL 505
+ G WVS D+ K +D+ A ++
Sbjct: 1558 D--GSTWVSMKNVRFLDDSILKRRDVGSAAFKI 1588
Score = 65.9 bits (159), Expect = 2e-08
Identities = 50/180 (27%), Positives = 85/180 (46%), Gaps = 26/180 (14%)
Query: 1773 GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYLLENVVAPA 1832
G FC+LPL I TGLP H+N F ++SNR++IW +D G WN + +V+ A
Sbjct: 1445 GEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIW-KTDTKG------RWNTTFMRHVIVKA 1497
Query: 1833 YGRLLEKVALEIGPC-----YLFFSLWP-KTLGLEPWASVIRKLYQFVAEFNLRVL-YTE 1885
Y ++L V ++ Y ++++WP L + ++ + + Y+ +A + L
Sbjct: 1498 YLQVL-SVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKELTKVF 1556
Query: 1886 ARGGQWISTKHAIFPDFSFPKADEL-----------IKALSGASLPVITLPQSLLERFME 1934
+ G W+S K+ F D S K ++ +K +L + LP S+ F E
Sbjct: 1557 SDGSTWVSMKNVRFLDDSILKRRDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKLGFEE 1616
>ref|XP_534533.1| PREDICTED: similar to sacsin [Canis familiaris]
Length = 4723
Score = 299 bits (765), Expect = 9e-79
Identities = 352/1460 (24%), Positives = 594/1460 (40%), Gaps = 212/1460 (14%)
Query: 13 DFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
+FGQ LT RI+ +L YP +LKEL+QNADDA AT + D R H D +
Sbjct: 2689 EFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKW 2748
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+ QGPAL YN+ FTEDD I +G +K G KTG++G+GFNSVYH+TD PSF+S
Sbjct: 2749 APLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPCKTGQYGIGFNSVYHITDCPSFIS 2808
Query: 133 GKYVV-LFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTL 191
G ++ +FDP Y P ++ +PG+ + + + D Y + + T+
Sbjct: 2809 GNDILCIFDPHARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGTHFKLDNC---TM 2865
Query: 192 FRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEP 251
FRFPLRNA+ A S++S + + ++ +L +G L+FL + I + D G
Sbjct: 2866 FRFPLRNAEMAKVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKGTG 2925
Query: 252 KPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVRQVDR 311
++S D + +Q + S+ ++ P++ +T + ++ +
Sbjct: 2926 ALNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTT 2985
Query: 312 FYIVQTMA-SASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTGQAFCFLP 370
+ I S+ ++ I+A K DI L P +AACI+ N + +AFCFLP
Sbjct: 2986 WLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACITHN-----YKKPHRAFCFLP 3040
Query: 371 LPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHML--- 427
L + TGL VNG F + S RR +W D+ VRS WN L+ L+APA+V +L
Sbjct: 3041 LSLETGLPFHVNGHFALDSARRNLWRDDN---GVGVRSDWNNSLMTALIAPAYVELLIQL 3097
Query: 428 --------------------HGVKELLGPTDIYYSLWPTGSFEEPWSI--LVQQIYINIC 465
H VK+ L + S +P + + LV+ +Y I
Sbjct: 3098 KKRYFPGSDPTLSVLQNTPIHVVKDTLKK---FLSFFPVNRLDLQPDLYCLVKALYSCIH 3154
Query: 466 N-----APVIYS-NLGGG--------RWVSPSEA---------FLHDE-KFTKSKDLSLA 501
PV+ + N+ G W++ S + L DE + K+ D ++
Sbjct: 3155 EDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTRPFFDNLLQDELQHLKNADYNIT 3214
Query: 502 ---------------LMQLGMPVVHLPN---SLFDMLLKYNSS-KVITPGTVRQFLRECE 542
L+++G +V+ + +L+ L+ + +TP VR FL
Sbjct: 3215 TRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLIDADIPVSYVTPADVRSFLMTFS 3274
Query: 543 S----CN-----------HLSRAHKL-LLLEYCLEDLVDDDVGKAAYNLPLLPLANGNFA 586
S C+ +L H L LL++YC +D ++++ LPLL +
Sbjct: 3275 SPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEENEI--EVEGLPLLITLDSVLQ 3332
Query: 587 SFLEASKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSNTNIA-LFSIH 645
+F +A + P F+ ++L+ D ++ + + S I + N +A +F I
Sbjct: 3333 TF-DAKR--PKFLTTY--HELIPSRKDLFMN-----TLYLKYSNILL--NCKVAKVFDIS 3380
Query: 646 HFAHLFPVFMPDDWKYKCKVFWDPDSCQKPTSSWFVLFWQYLGK-------QSEILPLF- 697
FA L +P ++K K W + + SW W ++ + Q E P+F
Sbjct: 3381 SFADLLSSVLPREYKTKNCTKWKDNFASE---SWLKNAWHFISESVNVKEDQEETQPIFD 3437
Query: 698 ------KDWPILPST------------SGHLLRPSRQLKM-INGSTLSDTVQDILVKIGC 738
KDW +LP T G +L P + + + + SD V L+K GC
Sbjct: 3438 IVVETLKDWALLPGTKFTVSANQLVVPEGDVLLPLSLMHIAVFPNAQSDKVFHALMKAGC 3497
Query: 739 HILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEE--RNELRRF 796
L + F L + A + + A + V S+ AE+ N+
Sbjct: 3498 IQLALNKICSKDSAFVPLLSCHTANIESP--TSILKAVHYMVQTSTFRAEKLVENDFEAL 3555
Query: 797 LLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKYLPPLDVPEFILV 856
L+ + H M + +I+ + LP Y+ ++F K +P +V ++
Sbjct: 3556 LMYFNCNLSHLMSQDDIKILKSLPCYKSISGRYMSIAKFGTCYVLTKSIPSAEVEKWTQS 3615
Query: 857 GIE-FIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSIMLSV---LQ 912
+ F+ + +E L G + + Y KH+ ++ L + + ++ + L
Sbjct: 3616 SLSAFLEEKIHLKE--LYEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLS 3673
Query: 913 NLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLEDSDSFPSGVFRE 972
++ LS + + L +L I LK YD +L + P F++
Sbjct: 3674 SIEELSEIKEQLFEKLESLLIIHDANSRLKQAKHFYDRTVRVFEVMLPEKLFIPKDFFKK 3733
Query: 973 SETL--------------DIMRGLGLKTSVSPDTVLESARCIE-HLMHEDQQKAYLKGKV 1017
E L + +R +GLK +S +L+ A+ I E+ K L+ V
Sbjct: 3734 LEQLIKPKNQATFMTSWVEFLRNIGLKYILSQQQLLQFAKEISVRANTENWSKETLQNTV 3793
Query: 1018 --LFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCP 1075
L ++ + L F + + + + A A R ++ L LI +
Sbjct: 3794 DILLHHIFQERMDLLSGNFLKELSLIPFLCPERAPAEFIR-FHPQYQEVNGTLPLIKFNG 3852
Query: 1076 VLVSPPFH-----SLPW---PVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLY 1127
V+P F L W P++ P + G + E L
Sbjct: 3853 AQVNPKFKQCDVLQLLWTSCPILPEKATPLSIRE--------QEGSDLGPQEQLEQVLSM 3904
Query: 1128 CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVK 1187
+ PP VI I L +E+ ++ + + +++ E +
Sbjct: 3905 LNVNLDPPLDKVI-------NNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREF-R 3956
Query: 1188 AVLEGCRWIWVGDGF--ATSDEVV--LDGPLHLAPYIRVIPVDLAVFKNLFLELGIREFL 1243
L G ++ V DG+ +EVV L+ PY+ +P++L F LF LG + +
Sbjct: 3957 FQLRGVAFVMVEDGWKLLKPEEVVINLEYESDFKPYLYKLPLELGTFHQLFKHLGTEDII 4016
Query: 1244 QPSDYVNILFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYLHG-----------QKVQLY 1292
YV +L R+ LD E+R V +V L + + + + LY
Sbjct: 4017 STKQYVEVLSRIFKNSEGKQLDPNEMRTVKRVVSGLFKSLQNDSVKVRSDLENVRDLALY 4076
Query: 1293 LPDVSGRLFLAGDLVYNDAP 1312
LP GRL + LV++DAP
Sbjct: 4077 LPSQDGRLVKSSILVFDDAP 4096
Score = 246 bits (629), Expect = 5e-63
Identities = 273/991 (27%), Positives = 420/991 (41%), Gaps = 157/991 (15%)
Query: 885 QFYKKHVFDRVGELQAEDRDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIG--TLK 942
QF+ + F + E++AE RD +M VL +++ S +LR IP + L
Sbjct: 2223 QFFYEVFFPNIQEIEAELRDPLMNFVLNE----KIDEFS--GILRVTPCIPCSLEGHPLV 2276
Query: 943 CPSVLYDPRNEEIYALLEDSDS-FPSGVFRESETLDIMRGL---GL-KTSVSPDTVLESA 997
PS L P + L + D FP G ++ I+ L G+ K + D +LE A
Sbjct: 2277 LPSRLIHPEGR-VAKLFDIKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERA 2335
Query: 998 RCIEHLMHEDQQKAYLKGKVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNT 1057
+ + + D A L+ +L S + D+K +I A F +R
Sbjct: 2336 QSVAEINKSDHAAACLRSSILLSLI------------DEKL----KIRDPRAKDFAAR-- 2377
Query: 1058 KSDIEKFWNDLQLISWCPVLVSPPFHSLPWPVVSSMVAPPKVVRPPNDLW------LVSA 1111
Q I + P L P SL W S P+ + DL+ +V
Sbjct: 2378 ----------YQTIPFLPFLTKPAGFSLDWKGNSFK---PETMFAAIDLYTAEHQDIVCL 2424
Query: 1112 GMRILDGE------CSSTALLY--CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQEL 1163
IL+ C S +L LG + P ++ QL E+ K+ V D V +
Sbjct: 2425 LQPILNENSHSFRGCGSVSLAVKEFLGLLRKPTVDLVVNQLKEVAKS---VDDGVTLYQE 2481
Query: 1164 ALAMPRIYSILTGMIGSDEIEI-VKAVLEGCRWIWVGDGFATSDEVVLDGPLHLAPYIRV 1222
+ + M+ ++ I+I + L+ +I V + + S++V APY+
Sbjct: 2482 NITNACYKYLHDAMMQNEMIKISIIEKLKPFSFILVENAYVDSEKVSFHLNFEAAPYLYQ 2541
Query: 1223 IPVDLAV-FKNLFLELGIREFLQPSDYVNILFRMANKKGSSPLDTQEIR--------AVM 1273
+P F+ LF +G+R+ D+ +L + +KG+ + + + +
Sbjct: 2542 LPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQEKGTKQITEENFQLCRRIISEGIW 2601
Query: 1274 LIVHHLAEVYLHGQKVQLYLPDVSGRLFLAGDLVYNDAPWLLGSEDPDGSFGNAPSVTWN 1333
++ + + ++ LPD + +L A L YND PW+
Sbjct: 2602 SLIREKKQEFCEKNYGKILLPDTNLKLLPAKSLCYNDCPWI------------------K 2643
Query: 1334 AKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLK 1393
K T K+ H +I +VA KLG R L A ++ F G FGQ E LT+R+K
Sbjct: 2644 VKDTTVKYCHADIPREVAVKLGAVPKRHKALERYASNICFTTLGTE--FGQKEKLTSRIK 2701
Query: 1394 HILEMYADGPGTLFELVQNAEDAGASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCFND 1453
IL Y L EL+QNA+DA A+E+ F+ D Q+ + + A QGPAL +N+
Sbjct: 2702 SILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNN 2761
Query: 1454 SVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIV-MFDPHAS 1512
FT D+ I +G+ +K G++G+GFN VYH TD P F+SG +I+ +FDPHA
Sbjct: 2762 QPFTEDDVRGIQNLGKGTKEGNPCKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHAR 2821
Query: 1513 NLPGISPSHPGLRIKFAGRKILEQFPDQFSSLL--HFGCDLQHPFPGTLFRFPLRTAGVA 1570
PG + PG + QF D L HF D T+FRFPLR A +A
Sbjct: 2822 YAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGTHFKLD-----NCTMFRFPLRNAEMA 2876
Query: 1571 SRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISIF-LKEGTGHEMRLLHRVSR 1629
S+I + V++L +E L+FL +++ ISI + +GTG + +L+ V
Sbjct: 2877 KVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKGTG-ALNVLYSV-- 2933
Query: 1630 ASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLSLSIDRDLPYKCQKILITEQGTH 1689
++ D DRL R QF + ID + K + +Q T
Sbjct: 2934 ---------KGKITD------GDRL---KRKQFHASV---IDSVTKKRQLKDIPVQQIT- 2971
Query: 1690 GRNSHYWIMTECLGGGNVLKGTSEASTSNSHNFVPW-ACVAAYLNSVKHGEDLVDSAEVE 1748
Y + TE + N W C + +S++ V SA
Sbjct: 2972 -----YTMDTE----------------DSEGNLTTWLICNRSGFSSMEKVSKSVISAHKN 3010
Query: 1749 DDCLVSSDLFQFASLPMHPRENFE--GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWF 1806
D LF + N++ RAFCFLPL + TGLP HVN +F L S RR++W
Sbjct: 3011 QDI----TLFPRGGVAACITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWR 3066
Query: 1807 GSDMTGGGRKRSDWNIYLLENVVAPAYGRLL 1837
+ G RSDWN L+ ++APAY LL
Sbjct: 3067 DDNGVG---VRSDWNNSLMTALIAPAYVELL 3094
Score = 224 bits (571), Expect = 3e-56
Identities = 197/680 (28%), Positives = 308/680 (44%), Gaps = 78/680 (11%)
Query: 14 FGQTVD-LTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
FGQT L ++++L YPEG +LKELIQNA+DAGAT V D + ++L S +
Sbjct: 150 FGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDM 209
Query: 73 SQWQG------------------------PALLAYNDAVFTEDDFISISKIGGSSKHGQA 108
+Q+QG PAL YN+AVFT +D+ I +I S K
Sbjct: 210 AQYQGIFSGGLELAGPDTVHQMPLSTGCRPALYVYNNAVFTPEDWHGIQEIARSRKKDDP 269
Query: 109 SKTGRFGVGFNSVYHLTDLPSFVSGKYVVLFDP-QGVYLPRVSAANPGKRIDFTGSSALS 167
K GRFG+GFNSVYH+TD+P SG + + DP Q ++ P S + D S +S
Sbjct: 270 LKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPHQTLFGPHESGQCWNLKDD---SKEIS 326
Query: 168 LYKDQFSPYCA-FGCD----MQSPFAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFV 222
DQF+P+ FG + + F GT FRFPLR S+LS Y + + +F
Sbjct: 327 ELSDQFAPFIGIFGSTKETFVNANFPGTFFRFPLR----LQPSQLSSNLYNKQKVLELFD 382
Query: 223 QLFEEGVLTLLFLKSVLCIEMYVWDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSL 282
+ LLFLKSV + ++V +A + V++ + + H +
Sbjct: 383 SFRADADTVLLFLKSVQDVSLHVREADGTEKLVFR---VTASENKALKHERPNSVKILET 439
Query: 283 NTTTEVDAFPLEFVTEAVRGVETVRQVDRFYIVQ-TMASASSRIGSFAITA---SKEYDI 338
+ P +T + V + + Q T + +G I+ S ++
Sbjct: 440 AISNYCKKIPSNSITCVTYHINIVLEDESTKDAQKTSWLVCNSVGGRGISGKLDSLADEL 499
Query: 339 QLLPWASIAACIS--DNSLNNDVLRTGQAFCFLPLP----VRTGLSVQVNGFFEVSSNRR 392
+ +P IA +S D +G+AFCFLPLP +TGL V ++GFF ++ NRR
Sbjct: 500 KFVPIIGIAMSLSRDDEEKGATADFSGKAFCFLPLPPGEESKTGLPVHISGFFGLTDNRR 559
Query: 393 GIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHM-LHGVKELLG--------PTDIYYSL 443
I + ++D+ ++WN L+ +V A+ + L +K L D+ Y L
Sbjct: 560 SIKW-RELDQWRDPAALWNEFLVMTVVPKAYATLILDSIKRLETERSSDFPLSVDLIYKL 618
Query: 444 WP-TGSFEEPWSILVQQIYINICNAPVIYSNLGGGRWVSPSEAFLH--DEKFTKSKDLSL 500
WP W +++ ++ + V+YS +WV +A+ DE + +K +
Sbjct: 619 WPDVSKVRVHWQPVLEPLFNELFQNAVMYSL--SNQWVKLEQAYFSELDESWECTKSVLS 676
Query: 501 ALMQLGMPVVHLPNSLFDMLLKYNSS----KVITPGTVRQFLRECESCNHLSRAHKLLLL 556
L G +V +P +L + SS + +TP VRQ LR +S + KL LL
Sbjct: 677 YLQSSGKHIVKVPPNLAAAVQLAASSAKPVRKVTPAWVRQVLR--KSAHPGGAQDKLHLL 734
Query: 557 EYCLEDLVDDDVGKAAYNLPLLPLANGNFASFLE--ASKGIPYFICDELEYKLLEPVSDR 614
E+ L D ++ L LLPL NGNF F + + + Y ++ L + R
Sbjct: 735 EFVLSDQAYSEL----LGLELLPLQNGNFVPFSSSVSDQDVIYITSEDYPRSLFPGLEGR 790
Query: 615 VIDQSIPPNILTRLSGIAMS 634
I S+ P+++ L A +
Sbjct: 791 FILDSLKPHLIAALKEAAQT 810
Score = 220 bits (561), Expect = 4e-55
Identities = 269/1033 (26%), Positives = 439/1033 (42%), Gaps = 132/1033 (12%)
Query: 637 TNIALFSIHHFAHLFPVFMPDDWKYK-CKVFWDPDSCQK--PTSSWFVLFWQYLGKQ-SE 692
T + L + FA L M W + V W P K P+ SW + W+ L SE
Sbjct: 901 TQLQLLNPERFARLIKEVMNTFWPGRELIVQWYPFDEDKNHPSVSWLKMVWKNLYIHFSE 960
Query: 693 ILPLFKDWPILPSTS---GHLLRPSRQLKMINGSTLSDTVQ--------DILVKIGCHIL 741
L LF + P++P T+ G +L++ + L D + DI+ K+G +L
Sbjct: 961 DLTLFDEMPLIPRTTLEEGQTCMELIRLRIPSLVILDDESEAQLPEFLADIVQKLGGIVL 1020
Query: 742 KP-GYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEERNELRRFLLDP 800
K ++HP + Y+ + VL+ + + + +SL+ ++ LR+FL
Sbjct: 1021 KKLDASIQHPLIKKYIHSPLPSAVLQIMEKM--PLQKLCNQIASLLPTHKDALRKFLASL 1078
Query: 801 QWYVGHSMDEFNIRFCRRLPIYQ-VYHREPTQDSQFSDLENPRKYLPPLDVPEFILVGIE 859
E R + LPI++ + H S ++ L+ + + + + I
Sbjct: 1079 T-----DSSEKEKRIIQELPIFKRINHLSDQGISSYTKLKGCKVLHHTAKLAPDLRLSIS 1133
Query: 860 FIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDS-IMLSVLQNLPLLS 918
++ SS+ L+ +E++ K + D + D + +ML +L+NL L
Sbjct: 1134 -VIDSSDEATIRLANMLKIEKLKTTHCIKLILRDIENAFYSHDEVTHLMLWILENLSSLK 1192
Query: 919 LEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALL--EDSDSFPSGVFRESETL 976
E+ ++ D L LKFI + L+DP E + L E+ FP VF + L
Sbjct: 1193 NENPNVLDWLMPLKFIQISQEQMVSAGELFDPDIEVLKDLFYNEEETCFPPSVFTSPDIL 1252
Query: 977 DIMRGLGLKT--SVSPDTVLESARCIEHLMHE---DQQKAYLKGKVLFSYLEVNALKWLP 1031
+R +GLK S+ + V++ A+ IE L +Q K K L L N +
Sbjct: 1253 HSLRQIGLKNEASLKENDVVQVAKKIEDLQVSSCPNQDILLKKAKTLLMVLNKNHM---- 1308
Query: 1032 DKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPVLVSPPFH---SLPWP 1088
+S K ++K I W P P + SL W
Sbjct: 1309 -------------------LLQSSEGKMTLKK-------IKWVPACKERPPNYPGSLVWK 1342
Query: 1089 V-VSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLGWMCPPGGGVIAAQLLEL 1147
V ++ APP + + + LV + + ++ E L LG P I+A L
Sbjct: 1343 GDVCNLCAPPDMCDGAHAI-LVGSSLPLV--ESVHINLEKALGIFTKPS---ISAVLKHF 1396
Query: 1148 GKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVKAVLEGCR--WIWVGDGFATS 1205
+ T + E I + G + D + K + W+W G F
Sbjct: 1397 KIVVDWYTSKTFSDEDYYQFQHILLEIYGFM-HDHLSEGKDAFRALKFPWVWTGKKFCPL 1455
Query: 1206 DEVVLDGPLH---LAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFRMANKKGSS 1262
+ V+ P H L PY+ +P +A F LF G E L SD+++++ + K
Sbjct: 1456 AQAVIK-PFHDLDLQPYLHSVPKTMAKFHQLFKVCGSIEELT-SDHISMVIQKVYLKSDQ 1513
Query: 1263 PLDTQEIRAVMLIVHHLAEVYLHGQ-------KVQLYLPDVSGRLFLAG-------DLVY 1308
L QE + + ++ ++ Q V ++ +L + D+
Sbjct: 1514 DLSDQESKQNLHLMLNIIRWLYSNQIPASPNTPVPIHHSKNPSKLIMKPIHECCYCDIKV 1573
Query: 1309 NDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAESA 1368
+D LL ED P + VH +I AE L V L L+ +
Sbjct: 1574 DDLNDLL--ED-----SVEPII----------LVHEDIPMKTAEWLKVPCLSTRLI--NP 1614
Query: 1369 DSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLD-- 1426
++M F E GQ E LT R+K+ILE Y EL+QNA+DA A+E F++D
Sbjct: 1615 ENMGF------EQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMR 1668
Query: 1427 KSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGF 1486
++ ++L P MA GPAL+ FN+S F+ D I+R+G+ K E+ +G+FGLGF
Sbjct: 1669 RNMDIRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKREEVDKVGKFGLGF 1728
Query: 1487 NCVYHFTDIPMFVSGENIVMFDPHASNLPG--ISPSHPGLRIKFA-GRKILEQFPDQFSS 1543
N VYH TDIP+ +S E ++MFDP+ +++ S+PG++I ++ +K L +FP+QF
Sbjct: 1729 NSVYHITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRKFPNQFKP 1788
Query: 1544 LLH-FGCDL------QHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVV 1596
+ FGC L + + GTLFR RT A S++ Y D+ SL FS
Sbjct: 1789 FIDVFGCQLPLTVEAPYSYSGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCG 1848
Query: 1597 SETLLFLRNVKSI 1609
++F ++V S+
Sbjct: 1849 HRLIIFTQSVTSM 1861
Score = 220 bits (561), Expect = 4e-55
Identities = 209/725 (28%), Positives = 329/725 (44%), Gaps = 111/725 (15%)
Query: 1343 HGNISNDVAEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEA-LTTRLKHILEMYAD 1401
H ++S+ + K+G +L+ L + S GL G FGQ L LK IL Y +
Sbjct: 116 HSSLSDWI--KIGDLTLKNHHLFVNLQSR--GLKGGGR-FGQTTPPLVDFLKDILRRYPE 170
Query: 1402 GPGTLFELVQNAEDAGASEVIFLLDKSQYGTSSVLSPEMADWQG---------------- 1445
G L EL+QNAEDAGA+EV FL D++QYGT ++ S +MA +QG
Sbjct: 171 GGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAQYQGIFSGGLELAGPDTVHQ 230
Query: 1446 --------PALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPM 1497
PALY +N++VFTP+D + I I + K + +GRFG+GFN VYH TD+P
Sbjct: 231 MPLSTGCRPALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPC 290
Query: 1498 FVSGENIVMFDPHASNLPGISPSHPGLRIKFAGRKILEQFPDQFSSLLH-FGCD----LQ 1552
SG+ I M DPH L G S +K ++I E DQF+ + FG +
Sbjct: 291 IFSGDQIGMLDPH-QTLFGPHESGQCWNLKDDSKEISE-LSDQFAPFIGIFGSTKETFVN 348
Query: 1553 HPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISIF 1612
FPGT FRFPLR SQ+ +Y + V LF +F LLFL++V+ +S+
Sbjct: 349 ANFPGTFFRFPLR----LQPSQLSSNLYNKQKVLELFDSFRADADTVLLFLKSVQDVSLH 404
Query: 1613 LKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLSLSIDR 1672
++E G E +L+ RV+ + A + N K ++ + + KK+ +
Sbjct: 405 VREADGTE-KLVFRVTASE------NKALKHERPNSVK---ILETAISNYCKKIPSNSIT 454
Query: 1673 DLPYKCQKILITEQGTHGRNSHYWIMTECLGGGNVLKGTSEASTSNSHNFVPWACVAAYL 1732
+ Y I++ ++ T W++ +GG + G + S ++ FVP +A L
Sbjct: 455 CVTYHI-NIVLEDESTKDAQKTSWLVCNSVGGRGI-SGKLD-SLADELKFVPIIGIAMSL 511
Query: 1733 NSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMHPRENFEGRAFCFLPLP----ISTGLP 1788
+ + E+ +A+ F G+AFCFLPLP TGLP
Sbjct: 512 S--RDDEEKGATAD------------------------FSGKAFCFLPLPPGEESKTGLP 545
Query: 1789 AHVNAYFELSSNRRDI-WFGSDMTGGGRKRSDWNIYLLENVVAPAYGRL----LEKVALE 1843
H++ +F L+ NRR I W ++ + WN +L+ VV AY L ++++ E
Sbjct: 546 VHISGFFGLTDNRRSIKW--RELDQWRDPAALWNEFLVMTVVPKAYATLILDSIKRLETE 603
Query: 1844 IGPCY-----LFFSLWPKTLGLE-PWASVIRKLYQFVAEFNLRVLYTEARGGQWISTKHA 1897
+ L + LWP + W V+ L+ + F V+Y + QW+ + A
Sbjct: 604 RSSDFPLSVDLIYKLWPDVSKVRVHWQPVLEPLFNEL--FQNAVMY--SLSNQWVKLEQA 659
Query: 1898 IFP--DFSFPKADELIKALSGASLPVITLPQSLLERFMEICPS---LHFLKPKLLRTLLI 1952
F D S+ ++ L + ++ +P +L S + + P +R +L
Sbjct: 660 YFSELDESWECTKSVLSYLQSSGKHIVKVPPNLAAAVQLAASSAKPVRKVTPAWVRQVLR 719
Query: 1953 RRKREFKDRDAMILTLEYCLHDFEESMQFDTLGGLPLLPLADGSFTSIEMKGIGERVYIA 2012
+ +D + L LE+ L D + L GL LLPL +G+F + V
Sbjct: 720 KSAHPGGAQDKLHL-LEFVLSD----QAYSELLGLELLPLQNGNFVPFSSSVSDQDVIYI 774
Query: 2013 RGDEY 2017
++Y
Sbjct: 775 TSEDY 779
Score = 188 bits (477), Expect = 2e-45
Identities = 155/580 (26%), Positives = 265/580 (44%), Gaps = 92/580 (15%)
Query: 5 SPESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAG 64
+PE++ E GQ LT RI+ +L YP + + KEL+QNADDA AT S +D R +
Sbjct: 1613 NPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMD 1672
Query: 65 --DSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVY 122
++LL ++ GPAL ++N++ F++ DF++I+++G S K + K G+FG+GFNSVY
Sbjct: 1673 IRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKREEVDKVGKFGLGFNSVY 1732
Query: 123 HLTDLPSFVSGKYVVLFDPQGVYLPR--VSAANPGKRIDFT-GSSALSLYKDQFSPYC-A 178
H+TD+P +S +++++FDP ++ + +NPG +I+++ L + +QF P+
Sbjct: 1733 HITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRKFPNQFKPFIDV 1792
Query: 179 FGCDM----QSP--FAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTL 232
FGC + ++P ++GTLFR R +A S++S Y DI S+ + G +
Sbjct: 1793 FGCQLPLTVEAPYSYSGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLI 1852
Query: 233 LFLKSVLCIEMYVWDAGEPKP-----------KKIHSCSVSSVSDDTIWHRQALLRLSKS 281
+F +SV + + E P K S ++S+ + L++ S
Sbjct: 1853 IFTQSVTSMYLKYLKIEETNPSLAQDTVIIKKKPCPSKALSAPVLSVLKEAARLMKTCSS 1912
Query: 282 LNTTTEVDA--------FPLEFVTEAVRGVETVR-------QVDRFYIVQTMASASSRIG 326
N DA +E R + ++ + D + + S S+
Sbjct: 1913 SNKKLPADAPKSSCILQITVEEFHHVFRRIADLQSPLFRGPEDDLTALFEMAKSGQSKKP 1972
Query: 327 SFAITASKEYDIQLLPWASIAACISDN-----SLNNDVLRTGQAFC-------------- 367
S + + ++ W I C+ SLN + R G C
Sbjct: 1973 SDEL---PQKTVECTTWL-ICTCMDTGEALKFSLNENGRRLGLVPCGAVGVLLSEIQDQK 2028
Query: 368 ----------FLPLPVR--TGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLL 415
F LP+R TGL V +NG F V+SNR+ IW D R WN +
Sbjct: 2029 WAVKPHVGEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTDTKGR-------WNTTFM 2081
Query: 416 EDLVAPAFVHMLHGVKELLGPTDI----YYSLWPTGSF-EEPWSILVQQIYINICNA--- 467
++ A++ L +++L ++ YYS+WP + +S++ Q Y +I +
Sbjct: 2082 RHVIVKAYLEALSVLRDLATNGELMDYTYYSVWPDPELVHDDFSVICQGFYEDIAHGKGK 2141
Query: 468 --PVIYSNLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQL 505
++S+ G WVS D+ K KD+ A ++
Sbjct: 2142 ELTRVFSD--GSMWVSMKNVRFLDDSILKRKDVGPAAFKI 2179
Score = 67.0 bits (162), Expect = 7e-09
Identities = 51/180 (28%), Positives = 83/180 (45%), Gaps = 26/180 (14%)
Query: 1773 GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYLLENVVAPA 1832
G FC+LPL I TGLP H+N F ++SNR++IW +D G WN + +V+ A
Sbjct: 2036 GEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIW-KTDTKG------RWNTTFMRHVIVKA 2088
Query: 1833 YGRLLEKVALEIGP-----CYLFFSLWP-KTLGLEPWASVIRKLYQFVAEFNLRVL-YTE 1885
Y L V ++ Y ++S+WP L + ++ + + Y+ +A + L
Sbjct: 2089 YLEAL-SVLRDLATNGELMDYTYYSVWPDPELVHDDFSVICQGFYEDIAHGKGKELTRVF 2147
Query: 1886 ARGGQWISTKHAIFPDFSFPKADEL-----------IKALSGASLPVITLPQSLLERFME 1934
+ G W+S K+ F D S K ++ +K +L + LP S+ F E
Sbjct: 2148 SDGSMWVSMKNVRFLDDSILKRKDVGPAAFKIFLKYLKKTGSKNLCAVELPSSVKSGFEE 2207
Score = 50.4 bits (119), Expect = 7e-04
Identities = 37/147 (25%), Positives = 77/147 (52%), Gaps = 16/147 (10%)
Query: 2050 TNISFLSCQLLEKLLVKLLPVEWQHASL-VSWTPGIHGQ--PSLEWLQLLWNYLKAN-CD 2105
T + L+ + +L+ +++ W L V W P + PS+ WL+++W L + +
Sbjct: 901 TQLQLLNPERFARLIKEVMNTFWPGRELIVQWYPFDEDKNHPSVSWLKMVWKNLYIHFSE 960
Query: 2106 DLLMFSKWPILP-----VGDDC--LIQLK-PNLNVIKNDGWS---EKMSSLLVKVGCLFL 2154
DL +F + P++P G C LI+L+ P+L ++ ++ + E ++ ++ K+G + L
Sbjct: 961 DLTLFDEMPLIPRTTLEEGQTCMELIRLRIPSLVILDDESEAQLPEFLADIVQKLGGIVL 1020
Query: 2155 RP-DLQLDHPKLECFVQSPTARGVLNV 2180
+ D + HP ++ ++ SP VL +
Sbjct: 1021 KKLDASIQHPLIKKYIHSPLPSAVLQI 1047
>gb|AAF31262.1| sacsin [Homo sapiens] gi|13124523|sp|Q9NZJ4|SACS_HUMAN Sacsin
Length = 3829
Score = 291 bits (744), Expect = 2e-76
Identities = 349/1460 (23%), Positives = 589/1460 (39%), Gaps = 212/1460 (14%)
Query: 13 DFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
+FGQ LT RI+ +L YP +LKEL+QNADDA AT + D R H D +
Sbjct: 1771 EFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKW 1830
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+ QGPAL YN+ FTEDD I +G +K G KTG++G+GFNSVYH+TD PSF+S
Sbjct: 1831 APLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPYKTGQYGIGFNSVYHITDCPSFIS 1890
Query: 133 GKYVV-LFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTL 191
G ++ +FDP Y P ++ +PG+ + + + D Y + + T+
Sbjct: 1891 GNDILCIFDPHARYAPGATSISPGRMFRDLDADFRTQFSDVLDLYLGTHFKLDNC---TM 1947
Query: 192 FRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEP 251
FRFPLRNA+ A S++S + + ++ +L +G L+FL + I + D
Sbjct: 1948 FRFPLRNAEMAKVSEISSVPASDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKSTG 2007
Query: 252 KPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVRQVDR 311
++S D + +Q + S+ ++ P++ +T + ++ +
Sbjct: 2008 ALNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTT 2067
Query: 312 FYIVQTMA-SASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTGQAFCFLP 370
+ I S+ ++ I+A K DI L P +AACI+ N + +AFCFLP
Sbjct: 2068 WLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACITHN-----YKKPHRAFCFLP 2122
Query: 371 LPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHM---- 426
L + TGL VNG F + S RR +W D+ VRS WN L+ L+APA+V +
Sbjct: 2123 LSLETGLPFHVNGHFALDSARRNLWRDDN---GVGVRSDWNNSLMTALIAPAYVELLIQL 2179
Query: 427 -------------------LHGVKELLGPTDIYYSLWPTGSFEEPWSI--LVQQIYINIC 465
+H VK+ L + S +P + + LV+ +Y I
Sbjct: 2180 KKRYFPGSDPTLSVLQNTPIHVVKDTLKK---FLSFFPVNRLDLQPDLYCLVKALYNCIH 2236
Query: 466 N-----APVIYS-NLGGG--------RWVSPSEA---------FLHDE-KFTKSKDLSLA 501
PV+ + N+ G W++ S + L DE + K+ D ++
Sbjct: 2237 EDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTRPFFDNLLQDELQHLKNADYNIT 2296
Query: 502 ---------------LMQLGMPVVHLPN---SLFDMLLKYNSS-KVITPGTVRQFLRECE 542
L+++G +V+ + +L+ L+ + +TP +R FL
Sbjct: 2297 TRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLIDADIPVSYVTPADIRSFLMTFS 2356
Query: 543 S----CN-----------HLSRAHKL-LLLEYCLEDLVDDDVGKAAYNLPLLPLANGNFA 586
S C+ +L H L LL++YC +D ++++ LPLL +
Sbjct: 2357 SPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEENEI--EVEGLPLLITLDSVLQ 2414
Query: 587 SFLEASKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSNTNIA-LFSIH 645
+F +A + P F+ ++L+ D ++ + + S I + N +A +F I
Sbjct: 2415 TF-DAKR--PKFLTTY--HELIPSRKDLFMN-----TLYLKYSNILL--NCKVAKVFDIS 2462
Query: 646 HFAHLFPVFMPDDWKYKCKVFWDPDSCQKPTSSWFVLFWQYLGK-------QSEILPLF- 697
FA L +P ++K K W + + SW W ++ + Q E P F
Sbjct: 2463 SFADLLSSVLPREYKTKSCTKWKDNFASE---SWLKNAWHFISESVSVKEDQEETKPTFD 2519
Query: 698 ------KDWPILPST------------SGHLLRPSRQLKM-INGSTLSDTVQDILVKIGC 738
KDW +LP T G +L P + + + + SD V L+K GC
Sbjct: 2520 IVVDTLKDWALLPGTKFTVSANQLVVPEGDVLLPLSLMHIAVFPNAQSDKVFHALMKAGC 2579
Query: 739 HILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEE--RNELRRF 796
L + F L + A + + A + V S+ AE+ N+
Sbjct: 2580 IQLALNKICSKDSAFVPLLSCHTANIESP--TSILKALHYMVQTSTFRAEKLVENDFEAL 2637
Query: 797 LLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKYLPPLDVPEFILV 856
L+ + H M + +I+ + LP Y+ +F K +P +V ++
Sbjct: 2638 LMYFNCNLNHLMSQDDIKILKSLPCYKSISGRYVSIGKFGTCYVLTKSIPSAEVEKWTQS 2697
Query: 857 GIE-FIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSIMLSV---LQ 912
F+ + +E L G + + Y KH+ ++ L + + ++ + L
Sbjct: 2698 SSSAFLEEKIHLKE--LYEVIGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLS 2755
Query: 913 NLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLEDSDSFPSGVFRE 972
+ LS + + L +L I LK YD +L + P+ F++
Sbjct: 2756 SAEELSEIKEQLFEKLESLLIIHDANSRLKQAKHFYDRTVRVFEVMLPEKLFIPNDFFKK 2815
Query: 973 SETL--------------DIMRGLGLKTSVSPDTVLESARCIE-HLMHEDQQKAYLKGKV 1017
E L + +R +GLK +S +L+ A+ I E+ K L+ V
Sbjct: 2816 LEQLIKPKNHVTFMTSWVEFLRNIGLKYILSQQQLLQFAKEISVRANTENWSKETLQNTV 2875
Query: 1018 --LFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCP 1075
L ++ + L F + + + + A A R ++ L LI +
Sbjct: 2876 DILLHHIFQERMDLLSGNFLKELSLIPFLCPERAPAEFIR-FHPQYQEVNGTLPLIKFNG 2934
Query: 1076 VLVSPPFH-----SLPW---PVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLY 1127
V+P F L W P++ P + G + E L
Sbjct: 2935 AQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKE--------QEGSDLGPQEQLEQVLNM 2986
Query: 1128 CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVK 1187
+ PP VI I L +E+ ++ + + +++ E +
Sbjct: 2987 LNVNLDPPLDKVI-------NNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREF-R 3038
Query: 1188 AVLEGCRWIWVGDGF--ATSDEVV--LDGPLHLAPYIRVIPVDLAVFKNLFLELGIREFL 1243
L G ++ V DG+ +EVV L+ PY+ +P++L F LF LG + +
Sbjct: 3039 FQLRGVAFVMVEDGWKLLKPEEVVINLEYESDFKPYLYKLPLELGTFHQLFKHLGTEDII 3098
Query: 1244 QPSDYVNILFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYLHG-----------QKVQLY 1292
YV +L R+ LD E+R V +V L + + + LY
Sbjct: 3099 STKQYVEVLSRIFKNSEGKQLDPNEMRTVKRVVSGLFRSLQNDSVKVRSDLENVRDLALY 3158
Query: 1293 LPDVSGRLFLAGDLVYNDAP 1312
LP GRL + LV++DAP
Sbjct: 3159 LPSQDGRLVKSSILVFDDAP 3178
Score = 243 bits (620), Expect = 6e-62
Identities = 274/1033 (26%), Positives = 431/1033 (41%), Gaps = 166/1033 (16%)
Query: 843 KYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAED 902
K L +++P + +G E + ++ +L + + QF+ + F + E++AE
Sbjct: 1272 KNLCAVELPSSVKLGFE----EAGCKQILLENTFS-----EKQFFSEVFFPNIQEIEAEL 1322
Query: 903 RDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIG--TLKCPSVLYDPRNEEIYALLE 960
RD +M+ VL +++ S +LR IP + L PS L P + L +
Sbjct: 1323 RDPLMIFVLNE----KVDEFS--GVLRVTPCIPCSLEGHPLVLPSRLIHPEGR-VAKLFD 1375
Query: 961 DSDS-FPSGVFRESETLDIMRGL---GL-KTSVSPDTVLESARCIEHLMHEDQQKAYLKG 1015
D FP G ++ I+ L G+ K + D +LE A + + D A L+
Sbjct: 1376 IKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAVSVAEINKSDHVAACLRS 1435
Query: 1016 KVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCP 1075
+L S + D+K R K K+ Q I + P
Sbjct: 1436 SILLSLI------------DEK------------LKIRDPRAKDFAAKY----QTIRFLP 1467
Query: 1076 VLVSPPFHSLPWPVVSSMVAPPKVVRPPNDLW------LVSAGMRILDGE------CSST 1123
L P SL W S P+ + DL+ +V IL+ C S
Sbjct: 1468 FLTKPAGFSLDWKGNSFK---PETMFAATDLYTAEHQDIVCLLQPILNENSHSFRGCGSV 1524
Query: 1124 ALLY--CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSD 1181
+L LG + P ++ QL E+ K+ V D + + + Y L + +
Sbjct: 1525 SLAVKEFLGLLKKPTVDLVINQLKEVAKS---VDDGITLYQENITNA-CYKYLHEALMQN 1580
Query: 1182 EIEIVKAV--LEGCRWIWVGDGFATSDEVVLDGPLHLAPYIRVIPVDLAV-FKNLFLELG 1238
EI + + L+ +I V + + S++V APY+ +P F+ LF +G
Sbjct: 1581 EITKMSIIDKLKPFSFILVENAYVDSEKVSFHLNFEAAPYLYQLPNKYKNNFRELFETVG 1640
Query: 1239 IREFLQPSDYVNILFRMANKKGSSPLDTQEIR--------AVMLIVHHLAEVYLHGQKVQ 1290
+R+ D+ +L + ++G+ + + + + ++ + + +
Sbjct: 1641 VRQSCTVEDFALVLESIDQERGTKQITEENFQLCRRIISEGIWSLIREKKQEFCEKNYGK 1700
Query: 1291 LYLPDVSGRLFLAGDLVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDV 1350
+ LPD + L A L YND PW+ K T K+ H +I +V
Sbjct: 1701 ILLPDTNLMLLPAKSLCYNDCPWI------------------KVKDTTVKYCHADIPREV 1742
Query: 1351 AEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELV 1410
A KLG R L A ++ F G FGQ E LT+R+K IL Y L EL+
Sbjct: 1743 AVKLGAVPKRHKALERYASNVCFTTLGTE--FGQKEKLTSRIKSILNAYPSEKEMLKELL 1800
Query: 1411 QNAEDAGASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQE 1470
QNA+DA A+E+ F+ D Q+ + + A QGPAL +N+ FT D+ I +G+
Sbjct: 1801 QNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKG 1860
Query: 1471 SKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIV-MFDPHASNLPGISPSHPGLRIKFA 1529
+K + G++G+GFN VYH TD P F+SG +I+ +FDPHA PG + PG +
Sbjct: 1861 TKEGNPYKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSISPGRMFRDL 1920
Query: 1530 GRKILEQFPDQFSSLL--HFGCDLQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRS 1587
QF D L HF D T+FRFPLR A +A S+I + V++
Sbjct: 1921 DADFRTQFSDVLDLYLGTHFKLD-----NCTMFRFPLRNAEMAKVSEISSVPASDRMVQN 1975
Query: 1588 LFAAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFN 1647
L +E L+FL +++ ISI + + + +L+ V ++ D
Sbjct: 1976 LLDKLRSDGAELLMFLNHMEKISICEIDKSTGALNVLYSV-----------KGKITD--- 2021
Query: 1648 FFKEDRLVGMNRAQFLKKLSLSIDRDLPYKCQKILITEQGTHGRNSHYWIMTECLGGGNV 1707
DRL R QF + ID + K + +Q T Y + TE
Sbjct: 2022 ---GDRL---KRKQFHASV---IDSVTKKRQLKDIPVQQIT------YTMDTE------- 2059
Query: 1708 LKGTSEASTSNSHNFVPW-ACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMH 1766
+ N W C + +S++ V SA D LF +
Sbjct: 2060 ---------DSEGNLTTWLICNRSGFSSMEKVSKSVISAHKNQDI----TLFPRGGVAAC 2106
Query: 1767 PRENFE--GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYL 1824
N++ RAFCFLPL + TGLP HVN +F L S RR++W + G RSDWN L
Sbjct: 2107 ITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVG---VRSDWNNSL 2163
Query: 1825 LENVVAPAYGRLL 1837
+ ++APAY LL
Sbjct: 2164 MTALIAPAYVELL 2176
Score = 213 bits (543), Expect = 5e-53
Identities = 260/1006 (25%), Positives = 434/1006 (42%), Gaps = 135/1006 (13%)
Query: 665 VFWDP--DSCQKPTSSWFVLFWQYLGKQ-SEILPLFKDWPILPST---SGHLLRPSRQLK 718
V W P ++ P+ SW + W+ L SE L LF + P++P T G +L+
Sbjct: 12 VQWYPFDENRNHPSVSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTILEEGQTCVELIRLR 71
Query: 719 MINGSTLSDTVQ--------DILVKIGCHILKP-GYVVEHPDLFSYLCGGNAAGVLESIF 769
+ + L D + DI+ K+G +LK ++HP + Y+ + VL+ +
Sbjct: 72 IPSLVILDDESEAQLPEFLADIVQKLGGFVLKKLDASIQHPLIKKYIHSPLPSAVLQIME 131
Query: 770 NAFSSAENMQVSFSSLIAEERNELRRFLLDPQWYVGHSMDEFNIRFCRRLPIYQ-VYHRE 828
+ + +SL+ ++ LR+FL E R + L I++ + H
Sbjct: 132 KM--PLQKLCNQITSLLPTHKDALRKFLASLT-----DSSEKEKRIIQELAIFKRINHSS 184
Query: 829 PTQDSQFSDLENPRKYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYK 888
S ++ L+ + +P + + I ++ SS+ L+ +E++ K
Sbjct: 185 DQGISSYTKLKGCKVLHHTAKLPADLRLSIS-VIDSSDEATIRLANMLKIEQLKTTSCLK 243
Query: 889 KHVFDRVGELQA-EDRDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVL 947
+ D + E+ +ML VL+NL L E+ ++ + L LKFI + L
Sbjct: 244 LVLKDIENAFYSHEEVTQLMLWVLENLSSLKNENPNVLEWLTPLKFIQISQEQMVSAGEL 303
Query: 948 YDPRNEEIYALL--EDSDSFPSGVFRESETLDIMRGLGLKT--SVSPDTVLESARCIEHL 1003
+DP E + L E+ FP VF + L +R +GLK S+ V++ A+ IE L
Sbjct: 304 FDPDIEVLKDLFCNEEGTYFPPSVFTSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEAL 363
Query: 1004 MH---EDQQKAYLKGKVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSD 1060
DQ K K L L N T +S K
Sbjct: 364 QVGACPDQDVLLKKAKTLLLVLNKNH-----------------------TLLQSSEGKMT 400
Query: 1061 IEKFWNDLQLISWCPVLVSPPFH---SLPWPV-VSSMVAPPKVVRPPNDLWLVSAGMRIL 1116
++K I W P P + SL W + ++ APP + + + L+ + + ++
Sbjct: 401 LKK-------IKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDVGHAI-LIGSSLPLV 452
Query: 1117 DGECSSTALLYCLGWMCPPGGGVIAA--QLLELGKNNEIVTDQVLRQELALAMPRIYSIL 1174
E L LG P + +++ +++ +D+ Q + + IY +
Sbjct: 453 --ESIHVNLEKALGIFTKPSLSAVLKHFKIVVDWYSSKTFSDEDYYQFQHILL-EIYGFM 509
Query: 1175 TGMI--GSDEIEIVKAVLEGCRWIWVGDGFATSDEVVLDGPLH---LAPYIRVIPVDLAV 1229
+ G D +K W+W G F + V+ P+H L PY+ +P +A
Sbjct: 510 HDHLNEGKDSFRALKFP-----WVWTGKKFCPLAQAVIK-PIHDLDLQPYLHNVPKTMAK 563
Query: 1230 FKNLFLELGIREFLQPSDYVNILFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYLHGQ-- 1287
F LF G E L SD+++++ + K L QE + + ++ ++ Q
Sbjct: 564 FHQLFKVCGSIEELT-SDHISMVIQKIYLKSDQDLSEQESKQNLHLMLNIIRWLYSNQIP 622
Query: 1288 -----KVQLYLPDVSGRLFLAG-------DLVYNDAPWLLGSEDPDGSFGNAPSVTWNAK 1335
V ++ +L + D+ +D LL ED P +
Sbjct: 623 ASPNTPVPIHHSKNPSKLIMKPIHECCYCDIKVDDLNDLL--ED-----SVEPII----- 670
Query: 1336 RTVQKFVHGNISNDVAEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHI 1395
VH +I AE L V L L+ + ++M F E GQ E LT R+K+I
Sbjct: 671 -----LVHEDIPMKTAEWLKVPCLSTRLI--NPENMGF------EQSGQREPLTVRIKNI 717
Query: 1396 LEMYADGPGTLFELVQNAEDAGASEVIFLLD--KSQYGTSSVLSPEMADWQGPALYCFND 1453
LE Y EL+QNA+DA A+E FL+D ++ ++L P MA GPAL+ FN+
Sbjct: 718 LEEYPSVSDIFKELLQNADDANATECSFLIDMRRNMDIRENLLDPGMAACHGPALWSFNN 777
Query: 1454 SVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIVMFDPHASN 1513
S F+ D I+R+G+ K + +G+FGLGFN VYH TDIP+ +S E ++MFDP+ ++
Sbjct: 778 SQFSDSDFVNITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINH 837
Query: 1514 LPG--ISPSHPGLRIKFA-GRKILEQFPDQFSSLLH-FGCDL------QHPFPGTLFRFP 1563
+ S+PG++I ++ +K L +FP+QF + FGC L + + GTLFR
Sbjct: 838 ISKHIKDKSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLTVEAPYSYNGTLFRLS 897
Query: 1564 LRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSI 1609
RT A S++ Y D+ SL FS ++F ++VKS+
Sbjct: 898 FRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVKSM 943
Score = 162 bits (410), Expect = 1e-37
Identities = 101/292 (34%), Positives = 167/292 (56%), Gaps = 22/292 (7%)
Query: 5 SPESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAG 64
+PE++ E GQ LT RI+ +L YP + + KEL+QNADDA AT S +D R +
Sbjct: 695 NPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFLIDMRRNMD 754
Query: 65 --DSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVY 122
++LL ++ GPAL ++N++ F++ DF++I+++G S K G+ K G+FG+GFNSVY
Sbjct: 755 IRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRGEVDKVGKFGLGFNSVY 814
Query: 123 HLTDLPSFVSGKYVVLFDPQGVYLPR--VSAANPGKRIDFT-GSSALSLYKDQFSPYC-A 178
H+TD+P +S +++++FDP ++ + +NPG +I+++ L + +QF P+
Sbjct: 815 HITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRKFPNQFKPFIDV 874
Query: 179 FGCDM----QSPFA--GTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTL 232
FGC + ++P++ GTLFR R +A S++S Y DI S+ + G +
Sbjct: 875 FGCQLPLTVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLI 934
Query: 233 LFLKSVLCIEMYVWDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNT 284
+F +SV MY+ K KI + S D I +++ SK+LNT
Sbjct: 935 IFTQSVK--SMYL------KYLKIEETNPSLAQDTVIIKKKSC--SSKALNT 976
Score = 74.7 bits (182), Expect = 4e-11
Identities = 43/153 (28%), Positives = 77/153 (50%), Gaps = 19/153 (12%)
Query: 363 GQAFCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPA 422
G+ FC+LPL ++TGL V +NG F V+SNR+ IW D R WN + ++ A
Sbjct: 1118 GEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTDTKGR-------WNTTFMRHVIVKA 1170
Query: 423 FVHMLHGVKELLGPTDI----YYSLWPTGSF-EEPWSILVQQIYINICNA-----PVIYS 472
++ +L +++L ++ YY++WP + +S++ Q Y +I + ++S
Sbjct: 1171 YLQVLSVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKELTKVFS 1230
Query: 473 NLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQL 505
+ G WVS D+ K +D+ A ++
Sbjct: 1231 D--GSTWVSMKNVRFLDDSILKRRDVGSAAFKI 1261
Score = 65.9 bits (159), Expect = 2e-08
Identities = 50/180 (27%), Positives = 85/180 (46%), Gaps = 26/180 (14%)
Query: 1773 GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYLLENVVAPA 1832
G FC+LPL I TGLP H+N F ++SNR++IW +D G WN + +V+ A
Sbjct: 1118 GEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIW-KTDTKG------RWNTTFMRHVIVKA 1170
Query: 1833 YGRLLEKVALEIGPC-----YLFFSLWP-KTLGLEPWASVIRKLYQFVAEFNLRVL-YTE 1885
Y ++L V ++ Y ++++WP L + ++ + + Y+ +A + L
Sbjct: 1171 YLQVL-SVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKELTKVF 1229
Query: 1886 ARGGQWISTKHAIFPDFSFPKADEL-----------IKALSGASLPVITLPQSLLERFME 1934
+ G W+S K+ F D S K ++ +K +L + LP S+ F E
Sbjct: 1230 SDGSTWVSMKNVRFLDDSILKRRDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKLGFEE 1289
Score = 46.2 bits (108), Expect = 0.013
Identities = 32/119 (26%), Positives = 64/119 (52%), Gaps = 15/119 (12%)
Query: 2077 LVSWTPGIHGQ--PSLEWLQLLWNYLKAN-CDDLLMFSKWPILP-----VGDDC--LIQL 2126
+V W P + PS+ WL+++W L + +DL +F + P++P G C LI+L
Sbjct: 11 IVQWYPFDENRNHPSVSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTILEEGQTCVELIRL 70
Query: 2127 K-PNLNVIKNDGWS---EKMSSLLVKVGCLFLRP-DLQLDHPKLECFVQSPTARGVLNV 2180
+ P+L ++ ++ + E ++ ++ K+G L+ D + HP ++ ++ SP VL +
Sbjct: 71 RIPSLVILDDESEAQLPEFLADIVQKLGGFVLKKLDASIQHPLIKKYIHSPLPSAVLQI 129
>ref|NP_056603.1| sacsin [Mus musculus] gi|6907044|gb|AAF31263.1| sacsin [Mus musculus]
gi|13124519|sp|Q9JLC8|SACS_MOUSE Sacsin
Length = 3830
Score = 282 bits (722), Expect = 9e-74
Identities = 353/1465 (24%), Positives = 591/1465 (40%), Gaps = 222/1465 (15%)
Query: 13 DFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
+FGQ LT RI+ +L YP +LKEL+QNADDA AT + D R H D +
Sbjct: 1771 EFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKW 1830
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+ QGPAL YN+ FTEDD I +G +K G KTG +G+GFNSVYH+TD PSF+S
Sbjct: 1831 APLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPCKTGHYGIGFNSVYHITDCPSFIS 1890
Query: 133 GKYVV-LFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTL 191
G ++ +FDP Y P ++ +PG+ + + + D Y + + T+
Sbjct: 1891 GNDILGIFDPHARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGNHFKLDNC---TM 1947
Query: 192 FRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEP 251
FRFPLRNA+ A S++S + + ++ +L +G L+FL + I + D
Sbjct: 1948 FRFPLRNAEMAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATG 2007
Query: 252 KPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVRQVDR 311
++S D + +Q + S+ ++ P++ +T + ++ +
Sbjct: 2008 GLNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTT 2067
Query: 312 FYIVQTMA-SASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTGQAFCFLP 370
+ I S+ ++ I+A K DI L P +AACI+ N + +AFCFLP
Sbjct: 2068 WLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACITHN-----YKKPHRAFCFLP 2122
Query: 371 LPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHM---- 426
L + TGL VNG F + S RR +W D+ VRS WN L+ L+APA+V +
Sbjct: 2123 LSLETGLPFHVNGHFALDSARRNLWRDDN---GVGVRSDWNNSLMTALIAPAYVELLIQL 2179
Query: 427 -------------------LHGVKELLGPTDIYYSLWPTGSFEEPWSI--LVQQIYINIC 465
+H VK+ L + S +P + + LV+ +Y I
Sbjct: 2180 KKRYFPGSDPTLSVLQNTPIHVVKDTLKK---FLSFFPVNRLDLQPDLYCLVKALYSCIH 2236
Query: 466 N-----APVIYS-NLGGG--------RWVSPSEA---------FLHDE-KFTKSKDLSLA 501
PV+ + N+ G W++ S + L DE + K+ D ++
Sbjct: 2237 EDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTRPFFDNLLQDELQHLKNADYNIT 2296
Query: 502 ---------------LMQLGMPVVHLPN---SLFDMLLKYNSS-KVITPGTVRQFLRECE 542
L+++G +V+ + +L+ L+ + +TP VR FL
Sbjct: 2297 TRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLVDADIPVSYVTPADVRSFLMTFS 2356
Query: 543 S----CN-----------HLSRAHKL-LLLEYCLEDLVDDDVGKAAYNLPLLPLANGNFA 586
S C+ +L H L LL++YC +D + + LPLL +
Sbjct: 2357 SPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEESEF--EVEGLPLLITLD---- 2410
Query: 587 SFLEASKGI-PYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSNTNIA-LFSI 644
S L+ G P F+ ++L+ D ++ + + S + + N +A +F I
Sbjct: 2411 SVLQIFDGKRPKFLTTY--HELIPSRKDLFMN-----TLYLKYSSVLL--NCKVAKVFDI 2461
Query: 645 HHFAHLFPVFMPDDWKYKCKVFWDPDSCQKPTSSWFVLFWQYLGK-------QSEILPLF 697
FA L +P ++K K W + + SW W ++ + Q E P F
Sbjct: 2462 SSFADLLSSVLPREYKTKNCAKWKDNFASE---SWLKNAWHFISESVSVTDDQEEPKPAF 2518
Query: 698 -------KDWPILPSTS------------GHLLRPSRQLKM-INGSTLSDTVQDILVKIG 737
KDW +LP T G +L P + + + + SD V L+K G
Sbjct: 2519 DVIVDILKDWALLPGTKFTVSTSQLVVPEGDVLIPLSLMHIAVFPNAQSDKVFHALMKAG 2578
Query: 738 CHILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEE--RNELRR 795
C L + L + A + + A + V S+ E+ N+
Sbjct: 2579 CIQLALNKICSKDSALVPLLSCHTANIDSPA--SILKAVHYMVQTSTFRTEKLMENDFEA 2636
Query: 796 FLLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKYLPPLDVPEFIL 855
L+ + H M + +I+ + LP Y+ ++F K +P +V ++
Sbjct: 2637 LLMYFNCNLSHLMSQDDIKILKSLPCYKSISGRYMSIAKFGTCYVLTKSIPSAEVEKWTQ 2696
Query: 856 VGIE-FIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSIMLSVLQNL 914
F+ + +E L G + + Y KH+ ++ L + D L L+N
Sbjct: 2697 SSSSAFLEEKVHLKE--LYEVLGCVPVDDLEVYLKHLLPKIENL-SYDAKLEHLIYLKNR 2753
Query: 915 PLLSLEDAS-----IRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLEDSDSFPSGV 969
L S+E+ S + + L +L I LK YD +L + P
Sbjct: 2754 -LASIEEPSEIKEQLFEKLESLLIIHDANNRLKQAKHFYDRTVRVFEVMLPEKLFIPKEF 2812
Query: 970 FRESETL--------------DIMRGLGLKTSVSPDTVLESARCIEHLMH-EDQQKAYLK 1014
F++ E + + +R +GLK ++S +L+ A+ I + E+ K L+
Sbjct: 2813 FKKLEQVIKPKNQAAFMTSWVEFLRNIGLKYALSQQQLLQFAKEISVRANTENWSKETLQ 2872
Query: 1015 GKV--LFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLIS 1072
V L ++ + L F + + + + A A R ++ L LI
Sbjct: 2873 STVDILLHHIFQERMDLLSGNFLKELSLIPFLCPERAPAEYIR-FHPQYQEVNGTLPLIK 2931
Query: 1073 WCPVLVSPPFHS-----LPW---PVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTA 1124
+ V+P F L W P++ P + G + E
Sbjct: 2932 FNGAQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKE--------QEGSDLAPQEQLEQV 2983
Query: 1125 LLYCLGWMCPPGGGVIAAQLLELGKNN--EIVTDQVLRQELALAMPRIYSILTGMIGSDE 1182
L + PP VI NN I L +E+ ++ + + +++
Sbjct: 2984 LNMLNVNLDPPLDKVI---------NNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEK 3034
Query: 1183 IEIVKAVLEGCRWIWVGDGFAT--SDEVV--LDGPLHLAPYIRVIPVDLAVFKNLFLELG 1238
E + L G ++ V DG+ +EVV L+ PY+ +P++L F LF LG
Sbjct: 3035 REF-RFQLRGVAFVMVEDGWKLLKPEEVVINLEYEADFKPYLYKLPLELGTFHQLFKHLG 3093
Query: 1239 IREFLQPSDYVNILFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYL-----------HGQ 1287
+ + YV +L R+ LD E+R V +V L + + +
Sbjct: 3094 TEDIISTKQYVEVLSRIFKSSEGKQLDPNEMRTVKRVVSGLFKSLQNDSVKVRSDLENAR 3153
Query: 1288 KVQLYLPDVSGRLFLAGDLVYNDAP 1312
+ LYLP G+L + LV++DAP
Sbjct: 3154 DLALYLPSQDGKLVKSSILVFDDAP 3178
Score = 234 bits (597), Expect = 3e-59
Identities = 265/992 (26%), Positives = 412/992 (40%), Gaps = 159/992 (16%)
Query: 885 QFYKKHVFDRVGELQAEDRDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIG--TLK 942
QF+ + F + E++AE RD +M VL L++ S +LR +P + L
Sbjct: 1305 QFFSEVFFPNIQEIEAELRDPLMNFVLNE----KLDEFS--GILRVTPCVPCSLEGHPLV 1358
Query: 943 CPSVLYDPRNEEIYALLEDSDS-FPSGVFRESETLDIMRGL---GL-KTSVSPDTVLESA 997
PS L P + L + D FP G ++ I+ L G+ K + D +LE A
Sbjct: 1359 LPSRLIHPEGR-VAKLFDTKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERA 1417
Query: 998 RCIEHLMHEDQQKAYLKGKVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNT 1057
+ + D A L+ +L S + D+K +I A F ++
Sbjct: 1418 ESVAEINKSDHAAACLRSSILLSLI------------DEKL----KIKDPRAKDFAAK-- 1459
Query: 1058 KSDIEKFWNDLQLISWCPVLVSPPFHSLPWPVVSSMVAPPKVVRPPNDLW------LVSA 1111
Q I + P L P SL W S P+ + D++ +V
Sbjct: 1460 ----------YQTIPFLPFLTKPAGFSLEWKGNSFK---PETMFAATDIYTAEYQDIVCL 1506
Query: 1112 GMRILDGE------CSSTALLY--CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQEL 1163
IL+ C S +L LG + P ++ QL ++ K+ V D + +
Sbjct: 1507 LQPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKQVAKS---VDDGITLYQE 1563
Query: 1164 ALAMPRIYSILTGMIGSDEIE---IVKAVLEGCRWIWVGDGFATSDEVVLDGPLHLAPYI 1220
+ Y L + +E+ I++ + C +I V + + S++V APY+
Sbjct: 1564 NITNA-CYKYLHEAVLQNEMAKATIIEKLKPFC-FILVENVYVESEKVSFHLNFEAAPYL 1621
Query: 1221 RVIPVDLAV-FKNLFLELGIREFLQPSDYVNILFRMANKKGSSPLDTQEIR--------A 1271
+P F+ LF +G+R+ D+ +L + ++G + + +
Sbjct: 1622 YQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQERGKKQITEENFQLCRRIISEG 1681
Query: 1272 VMLIVHHLAEVYLHGQKVQLYLPDVSGRLFLAGDLVYNDAPWLLGSEDPDGSFGNAPSVT 1331
+ ++ + + ++ LPD + L A L YND PW+
Sbjct: 1682 IWSLIREKRQEFCEKNYGKILLPDTNLLLLPAKSLCYNDCPWI----------------- 1724
Query: 1332 WNAKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTR 1391
K + K+ H +I +VA KLG R L A ++ F G FGQ E LT+R
Sbjct: 1725 -KVKDSTVKYCHADIPREVAVKLGAIPKRHKALERYASNICFTALGTE--FGQKEKLTSR 1781
Query: 1392 LKHILEMYADGPGTLFELVQNAEDAGASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCF 1451
+K IL Y L EL+QNA+DA A+E+ F+ D Q+ + + A QGPAL +
Sbjct: 1782 IKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVY 1841
Query: 1452 NDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIV-MFDPH 1510
N+ FT D+ I +G+ +K G +G+GFN VYH TD P F+SG +I+ +FDPH
Sbjct: 1842 NNQPFTEDDVRGIQNLGKGTKEGNPCKTGHYGIGFNSVYHITDCPSFISGNDILGIFDPH 1901
Query: 1511 ASNLPGISPSHPGLRIKFAGRKILEQFPDQFSSLL--HFGCDLQHPFPGTLFRFPLRTAG 1568
A PG + PG + QF D L HF D T+FRFPLR A
Sbjct: 1902 ARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGNHFKLD-----NCTMFRFPLRNAE 1956
Query: 1569 VASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLHRVS 1628
+A S+I + V++L +E L+FL +++ ISI + + +L+ V
Sbjct: 1957 MAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATGGLNVLYSV- 2015
Query: 1629 RASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLSLSIDRDLPYKCQKILITEQGT 1688
++ D DRL R QF + ID + K + +Q T
Sbjct: 2016 ----------KGKITD------GDRL---KRKQFHASV---IDSVTKKRQLKDIPVQQIT 2053
Query: 1689 HGRNSHYWIMTECLGGGNVLKGTSEASTSNSHNFVPW-ACVAAYLNSVKHGEDLVDSAEV 1747
Y + TE + N W C + +S++ V SA
Sbjct: 2054 ------YTMDTE----------------DSEGNLTTWLICNRSGFSSMEKVSKSVISAHK 2091
Query: 1748 EDDCLVSSDLFQFASLPMHPRENFE--GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIW 1805
D LF + N++ RAFCFLPL + TGLP HVN +F L S RR++W
Sbjct: 2092 NQDI----TLFPRGGVAACITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLW 2147
Query: 1806 FGSDMTGGGRKRSDWNIYLLENVVAPAYGRLL 1837
+ G RSDWN L+ ++APAY LL
Sbjct: 2148 RDDNGVG---VRSDWNNSLMTALIAPAYVELL 2176
Score = 214 bits (546), Expect = 2e-53
Identities = 263/1008 (26%), Positives = 435/1008 (43%), Gaps = 139/1008 (13%)
Query: 665 VFWDPDSCQK--PTSSWFVLFWQYLGKQ-SEILPLFKDWPILP-------STSGHLLR-- 712
V W P S K P+ SW + W+ L SE L LF + P++P T L+R
Sbjct: 12 VQWYPFSEDKRHPSLSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTLLNEDQTCVELIRLR 71
Query: 713 -PSRQLKMINGST---LSDTVQDILVKIGCHILKP-GYVVEHPDLFSYLCGGNAAGVLES 767
PS + +++ T L + + DI+ K+G +LK ++HP + Y+ + +L+
Sbjct: 72 IPS--VVILDDETEAQLPEFLADIVQKLGGIVLKRLDTSIQHPLVKKYIHSPLPSAILQI 129
Query: 768 IFNAFSSAENMQVSFSSLIAEERNELRRFLLDPQWYVGHSMDEFNIRFCRRLPIYQ-VYH 826
+ + + +SL+ ++ LR+FL E R + L I++ + H
Sbjct: 130 MEKI--PLQKLCNQIASLLPTHKDALRKFLASLT-----DTSEKEKRIIQELTIFKRINH 182
Query: 827 REPTQDSQFSDLENPRKYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQF 886
S ++ L+ + +P + + + ++ SS+ L+ +E++ K
Sbjct: 183 SSDQGISSYTKLKGCKVLDHTAKLPTDLRLSVS-VIDSSDEATIRLANMLKIEKL-KTTS 240
Query: 887 YKKHVFDRVGEL--QAEDRDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIGTLKCP 944
K V +G E+ +ML +L+NL L E++++ D L LKFI G +
Sbjct: 241 CLKFVLKDIGNAFYTQEEVTQLMLWILENLSSLKNENSNVLDWLMPLKFIHMSQGHVVAA 300
Query: 945 SVLYDPRNEEIYALL--EDSDSFPSGVFRESETLDIMRGLGLK--TSVSPDTVLESARCI 1000
L+DP E + L E+ FP +F + L +R +GLK +S+ V++ AR I
Sbjct: 301 GDLFDPDIEVLRDLFYNEEEACFPPTIFTSPDILHSLRQIGLKNESSLKEKDVVQVARKI 360
Query: 1001 EHLMHEDQQKAYLKGKVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSD 1060
E L Q D K + +L++ T +S K
Sbjct: 361 EALQVSSCQNQ--------------------DVLMKKAKTLLLVLNKNQTLLQSSEGKMA 400
Query: 1061 IEKFWNDLQLISWCPVLVSPPFH---SLPWPV-VSSMVAPPKVVRPPNDLWLVSAGMRIL 1116
++K I W P P + SL W + ++ APP + + + LV + + ++
Sbjct: 401 LKK-------IKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDAAHAV-LVGSSLPLV 452
Query: 1117 DGECSSTALLYCLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTG 1176
E L L P I A L + T + E I + G
Sbjct: 453 --ESVHVNLEQALSIFTKP---TINAVLKHFKTVVDWYTSKTFSDEDYYQFQHILLEIYG 507
Query: 1177 MI------GSDEIEIVKAVLEGCRWIWVGDGFATSDEVVLDGPLH---LAPYIRVIPVDL 1227
+ G D + +K W+W G F + V+ P H L PY+ +P +
Sbjct: 508 FMHDHLSEGKDSFKALKFP-----WVWTGKNFCPLAQAVIK-PTHDLDLQPYLYNVPKTM 561
Query: 1228 AVFKNLFLELGIREFLQPSDYVNILFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYLHGQ 1287
A F LF G E L SD+++++ + K L +E + + ++ ++ Q
Sbjct: 562 AKFHQLFKACGSIEELT-SDHISMVIQKVYLKSDQELSEEESKQNLHLMLNIMRWLYSNQ 620
Query: 1288 -------KVQLYLPDVSGRLFLAG-------DLVYNDAPWLLGSEDPDGSFGNAPSVTWN 1333
V +Y +L + D+ +D LL ED P +
Sbjct: 621 IPASPNTPVPIYHSRNPSKLVMKPIHECCYCDIKVDDLNDLL--ED-----SVEPII--- 670
Query: 1334 AKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLK 1393
VH +I AE L V L L+ + ++M F E GQ E LT R+K
Sbjct: 671 -------LVHEDIPMKTAEWLKVPCLSTRLI--NPENMGF------EQSGQREPLTVRIK 715
Query: 1394 HILEMYADGPGTLFELVQNAEDAGASEVIFLLD--KSQYGTSSVLSPEMADWQGPALYCF 1451
+ILE Y EL+QNA+DA A+E F++D ++ ++L P MA GPAL+ F
Sbjct: 716 NILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWSF 775
Query: 1452 NDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIVMFDPHA 1511
N+S F+ D I+R+G+ K + +G+FGLGFN VYH TDIP+ +S E ++MFDP+
Sbjct: 776 NNSEFSDSDFLNITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNI 835
Query: 1512 SNLPG--ISPSHPGLRIKFA-GRKILEQFPDQFSSLLH-FGCDL------QHPFPGTLFR 1561
+++ S+PG++I ++ +K L +FP+QF + FGC L + + GTLFR
Sbjct: 836 NHISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLAVEAPYSYNGTLFR 895
Query: 1562 FPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSI 1609
RT A S++ Y D+ SL FS ++F ++V S+
Sbjct: 896 LSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVNSM 943
Score = 159 bits (403), Expect = 8e-37
Identities = 98/291 (33%), Positives = 166/291 (56%), Gaps = 22/291 (7%)
Query: 5 SPESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAG 64
+PE++ E GQ LT RI+ +L YP + + KEL+QNADDA AT S +D R +
Sbjct: 695 NPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMD 754
Query: 65 --DSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVY 122
++LL ++ GPAL ++N++ F++ DF++I+++G S K G+ K G+FG+GFNSVY
Sbjct: 755 IRENLLDPGMAACHGPALWSFNNSEFSDSDFLNITRLGESLKRGEVDKVGKFGLGFNSVY 814
Query: 123 HLTDLPSFVSGKYVVLFDPQGVYLPR--VSAANPGKRIDFT-GSSALSLYKDQFSPYC-A 178
H+TD+P +S +++++FDP ++ + +NPG +I+++ L + +QF P+
Sbjct: 815 HITDIPIIMSREFMIMFDPNINHISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPFIDV 874
Query: 179 FGCDM----QSPFA--GTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTL 232
FGC + ++P++ GTLFR R +A S++S Y DI S+ + G +
Sbjct: 875 FGCQLPLAVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLI 934
Query: 233 LFLKSVLCIEMYVWDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLN 283
+F +SV + + E P S++ DTI ++ + SK+LN
Sbjct: 935 IFTQSVNSMYLKYLKIEETNP---------SLAQDTIIIKKKVCP-SKALN 975
Score = 70.1 bits (170), Expect = 9e-10
Identities = 41/153 (26%), Positives = 76/153 (48%), Gaps = 19/153 (12%)
Query: 363 GQAFCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPA 422
G+ FC+LPL ++TGL + +NG F V+SNR+ IW D R WN + ++ A
Sbjct: 1118 GEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIWKTDTKGR-------WNTTFMRHVIVKA 1170
Query: 423 FVHMLHGVKELLGPTDI----YYSLWPTGSF-EEPWSILVQQIYINICNA-----PVIYS 472
++ L +++L ++ YY++WP + +S++ + Y +I + ++S
Sbjct: 1171 YLQALSVLRDLAIGGELTDYTYYAVWPDPDLVHDDFSVICKGFYEDIAHGKGKELTRVFS 1230
Query: 473 NLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQL 505
+ G WVS D+ + KD+ A ++
Sbjct: 1231 D--GSMWVSMKNVRFLDDSILQRKDVGSAAFKI 1261
Score = 67.4 bits (163), Expect = 6e-09
Identities = 51/179 (28%), Positives = 85/179 (46%), Gaps = 24/179 (13%)
Query: 1773 GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYLLENVVAPA 1832
G FC+LPL I TGLP H+N F ++SNR++IW +D G WN + +V+ A
Sbjct: 1118 GEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIW-KTDTKG------RWNTTFMRHVIVKA 1170
Query: 1833 YGRLLEKVA-LEIG---PCYLFFSLWP-KTLGLEPWASVIRKLYQFVAEFNLRVL-YTEA 1886
Y + L + L IG Y ++++WP L + ++ + + Y+ +A + L +
Sbjct: 1171 YLQALSVLRDLAIGGELTDYTYYAVWPDPDLVHDDFSVICKGFYEDIAHGKGKELTRVFS 1230
Query: 1887 RGGQWISTKHAIFPDFSFPKADEL-----------IKALSGASLPVITLPQSLLERFME 1934
G W+S K+ F D S + ++ +K +L + LP S+ F E
Sbjct: 1231 DGSMWVSMKNVRFLDDSILQRKDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKAGFEE 1289
Score = 44.7 bits (104), Expect = 0.039
Identities = 32/119 (26%), Positives = 59/119 (48%), Gaps = 15/119 (12%)
Query: 2077 LVSWTPGIHGQ--PSLEWLQLLWNYLKAN-CDDLLMFSKWPILP---VGDD--C--LIQL 2126
+V W P + PSL WL+++W L + +DL +F + P++P + +D C LI+L
Sbjct: 11 VVQWYPFSEDKRHPSLSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTLLNEDQTCVELIRL 70
Query: 2127 KPNLNVIKNDGWSEKMSSLLVKV-----GCLFLRPDLQLDHPKLECFVQSPTARGVLNV 2180
+ VI +D ++ L + G + R D + HP ++ ++ SP +L +
Sbjct: 71 RIPSVVILDDETEAQLPEFLADIVQKLGGIVLKRLDTSIQHPLVKKYIHSPLPSAILQI 129
>ref|XP_224256.3| PREDICTED: similar to sacsin [Rattus norvegicus]
Length = 4801
Score = 282 bits (722), Expect = 9e-74
Identities = 349/1463 (23%), Positives = 589/1463 (39%), Gaps = 218/1463 (14%)
Query: 13 DFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
+FGQ LT RI+ +L YP +LKEL+QNADDA AT + D R H D +
Sbjct: 2742 EFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKW 2801
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+ QGPAL YN+ FTEDD I +G +K G KTG++G+GFNSVYH+TD PSF+S
Sbjct: 2802 APLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPCKTGQYGIGFNSVYHITDCPSFIS 2861
Query: 133 GKYVV-LFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTL 191
G ++ +FDP Y P ++ +PG+ + + + D Y + + T+
Sbjct: 2862 GNDILCIFDPHARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGNHFKLDNC---TM 2918
Query: 192 FRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEP 251
FRFPLRNA+ A S++S + + ++ +L +G L+FL + I + D
Sbjct: 2919 FRFPLRNAEMAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATG 2978
Query: 252 KPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVRQVDR 311
++S D + +Q + S+ ++ P++ +T + ++ +
Sbjct: 2979 GLNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTT 3038
Query: 312 FYIVQTMA-SASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTGQAFCFLP 370
+ I S+ ++ I+A + DI L P +AACI+ N + +AFCFLP
Sbjct: 3039 WLICNRSGFSSMDKVSKSVISAHRNQDITLFPRGGVAACITHN-----YKKPHRAFCFLP 3093
Query: 371 LPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHMLHGV 430
L + TGL VNG F + S RR +W D+ VRS WN L+ L+APA+V +L +
Sbjct: 3094 LSLETGLPFHVNGHFALDSARRNLWRDDN---GVGVRSDWNNSLMTALIAPAYVELLIQL 3150
Query: 431 KE-----------LLGPTDI---------YYSLWPTGSFEEPWSI--LVQQIYINICN-- 466
K+ +L T I + S +P + + LV+ +Y I
Sbjct: 3151 KKRYFPGSDPTLSVLQNTPIHVVKDTLKKFLSFFPVNRLDLQPDLYCLVKALYSCIHEDM 3210
Query: 467 ---APVIYS-NLGGG--------RWVSPSEA---------FLHDE-KFTKSKDLSLA--- 501
PV+ + N+ G W++ S + L DE + K+ D ++
Sbjct: 3211 KRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTKPFFDNLLQDELQHLKNADYNITTRK 3270
Query: 502 ------------LMQLGMPVVH-------LPNSLFDMLLKYNSSKVITPGTVRQFLRECE 542
L+++G +V+ L + L D + + +TP VR FL
Sbjct: 3271 TVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLVDAAIPVS---YVTPADVRSFLMTFS 3327
Query: 543 S----CN-----------HLSRAHKL-LLLEYCLEDLVDDDVGKAAYNLPLLPLANGNFA 586
S C+ +L H L LL++YC +D + + LPLL +
Sbjct: 3328 SPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEESEF--EVEGLPLLITLD---- 3381
Query: 587 SFLEASKGI-PYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSNTNIA-LFSI 644
S L+ G P F+ ++L+ D ++ + + S + + N +A +F I
Sbjct: 3382 SVLQIFDGKRPKFLTTY--HELIPSRKDLFMN-----TLYLKYSSVLL--NCKVAKVFDI 3432
Query: 645 HHFAHLFPVFMPDDWKYKCKVFWDPDSCQKPTSSWFVLFWQYLGK-------QSEILPLF 697
FA L +P ++K K W + + SW W ++ + Q E P F
Sbjct: 3433 SSFADLLSSVLPREYKTKNCAKWKDNFASE---SWLKNAWHFISESVSVTDDQEEPKPAF 3489
Query: 698 -------KDWPILPSTS------------GHLLRPSRQLKM-INGSTLSDTVQDILVKIG 737
KDW +LP T G +L P + + + + SD V L+K G
Sbjct: 3490 DVIVDILKDWALLPGTKFTVSASQLVVPEGDVLIPLSLMHIAVFPNAQSDKVFHALMKAG 3549
Query: 738 CHILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEE--RNELRR 795
C L + L + A + + A + V S+ E+ N+
Sbjct: 3550 CIQLALNKICSKDSALVPLLSCHTANIDSPA--SILKAVHYMVQTSTFRTEKLVENDFEA 3607
Query: 796 FLLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKYLPPLDVPEFIL 855
L+ + H M + +++ + LP Y+ ++F K +P +V ++
Sbjct: 3608 LLMYFNCNLSHLMSQDDLKILKSLPCYKSISGRYMSIAKFGTCYVLTKSIPSAEVEKWTQ 3667
Query: 856 VGIE-FIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSIMLSV---L 911
F+ + +E L G + + Y KH+ ++ L + + ++ + L
Sbjct: 3668 SSSSAFLEEKVHLKE--LYEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRL 3725
Query: 912 QNLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLEDSDSFPSGVFR 971
++ LS + + L +L I LK YD +L + P F+
Sbjct: 3726 ASIEELSETKEQLFEKLESLLIIHDANNRLKQAKHFYDRTVRVFEVMLPEKLFIPKEFFK 3785
Query: 972 ESETL--------------DIMRGLGLKTSVSPDTVLESARCIEHLMH-EDQQKAYLKGK 1016
+ E + + +R +GLK +S +L+ A+ I + E+ K L+
Sbjct: 3786 KLEQVIKPKNQVVFMTSWVEFLRNIGLKHVLSQQQLLQFAKEISVRANTENWSKETLQNT 3845
Query: 1017 V--LFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWC 1074
V L ++ L F + + + + A A R ++ L LI +
Sbjct: 3846 VDILLHHIFQERTDLLSGNFLKELSLIPFLCPERAPAEYIR-FHPQYQEVNGTLPLIKFN 3904
Query: 1075 PVLVSPPFHS-----LPW---PVVSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALL 1126
V+P F L W P++ P + G + E L
Sbjct: 3905 GAQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKE--------QEGSSLAPQEQLEQVLN 3956
Query: 1127 YCLGWMCPPGGGVIAAQLLELGKNN--EIVTDQVLRQELALAMPRIYSILTGMIGSDEIE 1184
+ PP VI NN I L +E+ ++ + + +++ E
Sbjct: 3957 MLNVNLDPPLDKVI---------NNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKRE 4007
Query: 1185 IVKAVLEGCRWIWVGDGFAT--SDEVV--LDGPLHLAPYIRVIPVDLAVFKNLFLELGIR 1240
+ L G ++ V DG+ +EVV L+ PY+ +P++L F LF LG
Sbjct: 4008 F-RFQLRGVAFVMVEDGWKLLKPEEVVINLEYEADFKPYLYKLPLELGTFHQLFKHLGTE 4066
Query: 1241 EFLQPSDYVNILFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYL-----------HGQKV 1289
+ + YV +L R+ LD E+R V +V L + + + +
Sbjct: 4067 DIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRVVSGLFKSLQNDSVKVRSDLENARDL 4126
Query: 1290 QLYLPDVSGRLFLAGDLVYNDAP 1312
LYLP GRL + LV++DAP
Sbjct: 4127 ALYLPSQDGRLVKSSILVFDDAP 4149
Score = 240 bits (613), Expect = 4e-61
Identities = 199/661 (30%), Positives = 311/661 (46%), Gaps = 60/661 (9%)
Query: 14 FGQTVD-LTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
FGQT L ++++L YPEG +LKELIQNA+DAGAT V D + ++L S +
Sbjct: 203 FGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDM 262
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+Q+QG AL YN+AVFT +D+ I +I S K K GRFG+GFNSVYH+TD+P S
Sbjct: 263 AQYQGSALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFS 322
Query: 133 GKYVVLFDP-QGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYC-AFGCDMQS----P 186
G + + DP Q ++ P S + D + L DQF+P+ FG ++
Sbjct: 323 GDQIGMLDPHQTLFGPHESGQCWNLKDDIKEINEL---PDQFAPFIGVFGSTKETFTNGS 379
Query: 187 FAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVW 246
F GT FRFPLR S+LS YT + + +F + LLFLKSV + ++V
Sbjct: 380 FPGTFFRFPLR----LQPSQLSSNLYTKQKVLELFDSFRADADTVLLFLKSVQAVSLHVR 435
Query: 247 DAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETV 306
+A + V++ + T+ H + + P VT +
Sbjct: 436 EADGTEKLVFR---VTASENKTLKHERPNSIKILGTAISNYCKKIPSNSVTCVTYHINIA 492
Query: 307 RQVDRFYIVQ-TMASASSRIGSFAITA---SKEYDIQLLPWASIAACISDNSLNNDVLR- 361
+ + Q T + +G I++ S +++ +P +A +S N
Sbjct: 493 LEDESTKDAQKTSWLVCNSVGGRGISSKLDSLADELKFVPIIGLAMSLSGRDEENGATSD 552
Query: 362 -TGQAFCFLPLP----VRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLE 416
+G+AFCFLPLP RTGL V ++GFF ++ NRR I + ++D+ ++WN+ L+
Sbjct: 553 FSGKAFCFLPLPPGEESRTGLPVHISGFFGLTDNRRSIKW-RELDQWRDPAALWNQFLIV 611
Query: 417 DLVAPAFVHM-LHGVKELLG--------PTDIYYSLWPTGS-FEEPWSILVQQIYINICN 466
++V A+ + L +K L D Y LWP S + W ++ ++ +
Sbjct: 612 NVVPKAYATLILDSIKRLETEKSSDFPLSVDAIYKLWPEASKVKAHWHPVLGPLFSELFQ 671
Query: 467 APVIYSNLGGGRWVSPSEAFLH--DEKFTKSKDLSLALMQLGMPVVHLPNSLFDMLLKYN 524
VIYS GG WV + DE ++ + L + G + +P +L +
Sbjct: 672 HAVIYS--VGGEWVKLEQVHFSELDESLESTQSVLNYLQRSGKQIARVPGNLAAAVQLSA 729
Query: 525 SS--------KVITPGTVRQFLRECESCNHLSRA-HKLLLLEYCLEDLVDDDVGKAAYNL 575
+S + +TP VRQ LR+C HL A KL LLE+ L D ++ L
Sbjct: 730 ASATSTASPVRKVTPVWVRQVLRKCA---HLGSAEEKLHLLEFVLSDQAYSEL----LGL 782
Query: 576 PLLPLANGNFASFLE--ASKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAM 633
LLPL +G F F + + + Y +E L + R+I +++ P++L L A
Sbjct: 783 ELLPLQSGAFVPFSSSVSDQDVVYITSEEFPRSLFPGLEARLILENLKPHLLAALKEAAQ 842
Query: 634 S 634
+
Sbjct: 843 T 843
Score = 236 bits (602), Expect = 7e-60
Identities = 206/708 (29%), Positives = 327/708 (46%), Gaps = 87/708 (12%)
Query: 1341 FVHGNISNDVAEKLGVRSLRRMLLAESADSMNFGLSGAAEA-FGQHEA-LTTRLKHILEM 1398
F+H + + + GV R+ L+ S +E+ FGQ L LK IL
Sbjct: 161 FLHPPLHIFLLKTAGVEQCRQDLVINLVSHWASAPSVTSESRFGQTTPPLVDFLKDILRR 220
Query: 1399 YADGPGTLFELVQNAEDAGASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCFNDSVFTP 1458
Y +G L EL+QNAEDAGA+EV FL D++QYGT ++ S +MA +QG ALY +N++VFTP
Sbjct: 221 YPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAQYQGSALYVYNNAVFTP 280
Query: 1459 QDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIVMFDPHASNLPGIS 1518
+D + I I + K + +GRFG+GFN VYH TD+P SG+ I M DPH L G
Sbjct: 281 EDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPH-QTLFGPH 339
Query: 1519 PSHPGLRIKFAGRKILEQFPDQFSSLLH-FGCDLQ----HPFPGTLFRFPLRTAGVASRS 1573
S +K K + + PDQF+ + FG + FPGT FRFPLR S
Sbjct: 340 ESGQCWNLK-DDIKEINELPDQFAPFIGVFGSTKETFTNGSFPGTFFRFPLR----LQPS 394
Query: 1574 QIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLHRVSRASLG 1633
Q+ +YT + V LF +F LLFL++V+++S+ ++E G E +L+ RV+ +
Sbjct: 395 QLSSNLYTKQKVLELFDSFRADADTVLLFLKSVQAVSLHVREADGTE-KLVFRVTAS--- 450
Query: 1634 ESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLSLSIDRDLPYKCQKILITEQGTHGRNS 1693
E++ E + +++G + + KK+ + + Y I + ++ T
Sbjct: 451 ENKTLKHERPNSI------KILGTAISNYCKKIPSNSVTCVTYHI-NIALEDESTKDAQK 503
Query: 1694 HYWIMTECLGGGNVLKGTSEASTSNSHNFVPWACVAAYLNSVKHGEDLVDSAEVEDDCLV 1753
W++ +GG + + S ++ FVP +A L+ G D + A
Sbjct: 504 TSWLVCNSVGGRGI--SSKLDSLADELKFVPIIGLAMSLS----GRDEENGA-------- 549
Query: 1754 SSDLFQFASLPMHPRENFEGRAFCFLPLP----ISTGLPAHVNAYFELSSNRRDI-WFGS 1808
+F G+AFCFLPLP TGLP H++ +F L+ NRR I W
Sbjct: 550 --------------TSDFSGKAFCFLPLPPGEESRTGLPVHISGFFGLTDNRRSIKW--R 593
Query: 1809 DMTGGGRKRSDWNIYLLENVVAPAYGRL----LEKVALEIGPCY-----LFFSLWPKTLG 1859
++ + WN +L+ NVV AY L ++++ E + + LWP+
Sbjct: 594 ELDQWRDPAALWNQFLIVNVVPKAYATLILDSIKRLETEKSSDFPLSVDAIYKLWPEASK 653
Query: 1860 LEP-WASVIRKLYQFVAEFNLRVLYTEARGGQWISTKHAIFP--DFSFPKADELIKALSG 1916
++ W V+ L+ + F V+Y+ GG+W+ + F D S ++ L
Sbjct: 654 VKAHWHPVLGPLFSEL--FQHAVIYSV--GGEWVKLEQVHFSELDESLESTQSVLNYLQR 709
Query: 1917 ASLPVITLPQSLLERFMEICPS-------LHFLKPKLLRTLLIRRKREFKDRDAMILTLE 1969
+ + +P +L S + + P +R +L R+ + + LE
Sbjct: 710 SGKQIARVPGNLAAAVQLSAASATSTASPVRKVTPVWVRQVL-RKCAHLGSAEEKLHLLE 768
Query: 1970 YCLHDFEESMQFDTLGGLPLLPLADGSFTSIEMKGIGERVYIARGDEY 2017
+ L D + L GL LLPL G+F + V +E+
Sbjct: 769 FVLSD----QAYSELLGLELLPLQSGAFVPFSSSVSDQDVVYITSEEF 812
Score = 222 bits (566), Expect = 1e-55
Identities = 264/1033 (25%), Positives = 422/1033 (40%), Gaps = 166/1033 (16%)
Query: 843 KYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAED 902
K L +++P + VG E + ++ +L + + QF+ + F + E++AE
Sbjct: 2243 KNLCAVELPSSVKVGFE----EAGCKQILLENTFS-----EKQFFSEVFFPNIQEIEAEL 2293
Query: 903 RDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIG--TLKCPSVLYDPRNEEIYALLE 960
RD +M VL L++ S +LR +P + L PS L P + L +
Sbjct: 2294 RDPLMNFVLNE----KLDEFS--GILRVTPCVPCSLEGHPLVLPSRLIHPEGR-VAKLFD 2346
Query: 961 DSDS-FPSGVFRESETLDIMRGL---GL-KTSVSPDTVLESARCIEHLMHEDQQKAYLKG 1015
D FP G ++ I+ L G+ K + D +LE A + + D A L+
Sbjct: 2347 IKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAESVAEINKSDHAAACLRS 2406
Query: 1016 KVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCP 1075
+L S + D+K R K K+ Q I + P
Sbjct: 2407 SILLSLI------------DEK------------LKIRDPRAKDFAAKY----QTIPFLP 2438
Query: 1076 VLVSPPFHSLPWPVVSSMVAPPKVVRPPNDLW------LVSAGMRILDGE------CSST 1123
L P SL W S P+ + DL+ +V IL+ C S
Sbjct: 2439 FLTKPAGFSLEWKGNSFK---PETMFAATDLYTAEYQDIVCLLQPILNENSHSFRGCGSV 2495
Query: 1124 ALLY--CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSD 1181
+L LG + P ++ QL ++ K+ V D + + + Y L I +
Sbjct: 2496 SLAVKEFLGLLKKPTVDLVINQLKQVAKS---VDDGITLYQENITNA-CYKYLHEAILQN 2551
Query: 1182 EIE---IVKAVLEGCRWIWVGDGFATSDEVVLDGPLHLAPYIRVIPVDLAV-FKNLFLEL 1237
E+ I++ + C +I V + + S++V APY+ +P F+ LF +
Sbjct: 2552 EMAKATIIEKLKPFC-FILVENVYVESEKVSFHLNFEAAPYLYQLPNKYKNNFRELFESV 2610
Query: 1238 GIREFLQPSDYVNILFRMANKKGSSPLDTQEIR--------AVMLIVHHLAEVYLHGQKV 1289
G+R+ D+ +L + ++G + + + + ++ + +
Sbjct: 2611 GVRQSFTVEDFALVLESIDQERGKKQITEENFQLCRRIISEGIWSLIREKRQEFCEKNYG 2670
Query: 1290 QLYLPDVSGRLFLAGDLVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISND 1349
++ LPD + L A L YND PW+ K + K+ H +I +
Sbjct: 2671 KILLPDTNLLLLPAKSLCYNDCPWI------------------KVKDSSVKYCHADIPRE 2712
Query: 1350 VAEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFEL 1409
VA KLG R L A ++ F G FGQ E LT+R+K IL Y L EL
Sbjct: 2713 VAVKLGAIPKRHKALERYASNICFTAPGTE--FGQKEKLTSRIKSILNAYPSEKEMLKEL 2770
Query: 1410 VQNAEDAGASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQ 1469
+QNA+DA A+E+ F+ D Q+ + + A QGPAL +N+ FT D+ I +G+
Sbjct: 2771 LQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGK 2830
Query: 1470 ESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIV-MFDPHASNLPGISPSHPGLRIKF 1528
+K G++G+GFN VYH TD P F+SG +I+ +FDPHA PG + PG +
Sbjct: 2831 GTKEGNPCKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSVSPGRMFRD 2890
Query: 1529 AGRKILEQFPDQFSSLL--HFGCDLQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVR 1586
QF D L HF D T+FRFPLR A +A S+I + V+
Sbjct: 2891 LDADFRTQFSDVLDLYLGNHFKLD-----NCTMFRFPLRNAEMAQVSEISSVPSSDRMVQ 2945
Query: 1587 SLFAAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVF 1646
+L +E L+FL +++ ISI + + +L+ V G+ G + F
Sbjct: 2946 NLLDKLRSDGAELLMFLNHMEKISICEIDKATGGLNVLYSVK----GKITDGDRLKRKQF 3001
Query: 1647 NFFKEDRLVGMNRAQFLKKLSLSIDRDLPYKCQKILITEQGTHGRNSHYWIMTECLGGGN 1706
+ D + KK L +D+P + + + + G N W++
Sbjct: 3002 HASVIDSVT--------KKRQL---KDIPVQQITYTMDTEDSEG-NLTTWLI-------- 3041
Query: 1707 VLKGTSEASTSNSHNFVPWACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMH 1766
N F V+ + S +D+ LF +
Sbjct: 3042 ----------CNRSGFSSMDKVSKSVISAHRNQDIT--------------LFPRGGVAAC 3077
Query: 1767 PRENFEGRAFCFLPLPIS--TGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYL 1824
N++ F LP+S TGLP HVN +F L S RR++W + G RSDWN L
Sbjct: 3078 ITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVG---VRSDWNNSL 3134
Query: 1825 LENVVAPAYGRLL 1837
+ ++APAY LL
Sbjct: 3135 MTALIAPAYVELL 3147
Score = 218 bits (556), Expect = 2e-54
Identities = 269/1036 (25%), Positives = 447/1036 (42%), Gaps = 138/1036 (13%)
Query: 637 TNIALFSIHHFAHLFPVFMPDDWKYK-CKVFWDPDSCQK--PTSSWFVLFWQYLGKQ-SE 692
T + L + FA L M W + V W P S K P+ SW + W+ L SE
Sbjct: 954 TQLQLLNPERFARLIKEVMNTFWPGRELVVQWYPLSEDKHHPSISWLKMVWKNLYIHFSE 1013
Query: 693 ILPLFKDWPILP-------STSGHLLR---PSRQLKMINGST---LSDTVQDILVKIGCH 739
L LF + P++P T L+R PS + +++ T L + + DI+ K+G
Sbjct: 1014 DLTLFDEMPLIPRTPLDADQTCVELIRLRVPS--VVILDDETEAQLPEFLADIVQKLGGI 1071
Query: 740 ILKP-GYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEERNELRRFLL 798
+LK ++HP + Y+ + +L+ + + + +SL+ ++ LR+FL
Sbjct: 1072 VLKRLDTSLQHPLVKKYIHSPLPSAILQIMEKI--PLQKLCNQIASLLPTHKDALRKFLA 1129
Query: 799 DPQWYVGHSMDEFNIRFCRRLPIYQ-VYHREPTQDSQFSDLENPRKYLPPLDVPEFILVG 857
E R + L I++ + H S ++ L+ + +P + +
Sbjct: 1130 SLT-----DTSEKEKRIIQELTIFKRINHSSDQGISSYTKLKGCKVLDHTAKLPTELRLS 1184
Query: 858 IEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDS-IMLSVLQNLPL 916
+ ++ SS+ L+ +E++ K + D ++ + +ML +L+NL
Sbjct: 1185 VS-VIDSSDEATIRLANMLKIEKLKTTSCLKFVLKDIENAFYTQEEVTRLMLWILENLSS 1243
Query: 917 LSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALL--EDSDSFPSGVFRESE 974
L E+ S+ D L LKFI + S L+DP E + L E+ FP VF +
Sbjct: 1244 LKNENPSVLDWLMPLKFIHMSQEHVVAASDLFDPDIEVLRDLFYNEEEACFPPAVFTSPD 1303
Query: 975 TLDIMRGLGLKT--SVSPDTVLESARCIEHLMHEDQQKAYLKGKVLFSYLEVNALKWLPD 1032
L +R +GLK S+ V++ A+ IE L Q D
Sbjct: 1304 ILHSLRQIGLKNEASLKEKDVVQVAKKIEALQVSSCQNQ--------------------D 1343
Query: 1033 KFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPVLVSPPFH---SLPWPV 1089
K + +L++ T +S K ++K I W P P + SL W
Sbjct: 1344 VLLKKAKTLLLVLNKNHTLLQSSEGKMALKK-------IKWVPACKERPPNYPGSLVWKG 1396
Query: 1090 -VSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLGWMCPPGGGVIAAQLLELG 1148
+ ++ APP + + + LV + + ++ E + +L LG P I+A L
Sbjct: 1397 DLCNLCAPPDMCDAAHAV-LVGSSLPLV--ESAHVSLEKTLGIFTKP---TISAVLKHFK 1450
Query: 1149 KNNEIVTDQVLRQELALAMPRIYSILTGMI------GSDEIEIVKAVLEGCRWIWVGDGF 1202
+ T + E I + G + G D + +K W+W G F
Sbjct: 1451 IVVDWYTSKTFSDEDYYQFQHILLEIYGFMHDHLSEGKDSFKALKYP-----WVWTGKNF 1505
Query: 1203 ATSDEVVLDGPLH---LAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFRMANKK 1259
+ V+ P+H L PY+ +P +A F LF G E L SD+++++ + K
Sbjct: 1506 CPLAQAVIK-PIHDLDLQPYLYNVPKTMAKFHQLFKACGSIEELT-SDHISMVIQKVYLK 1563
Query: 1260 GSSPLDTQEIRAVMLIVHHLAEVYLHGQ-------KVQLYLPDVSGRLFLAG-------D 1305
L +E + + ++ ++ Q V +Y +L + D
Sbjct: 1564 SDQELSEEESKQNLHLMLNIMRWLYSNQIPASPNTPVPIYHSKNPSKLVMKPIHECCYCD 1623
Query: 1306 LVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRRMLLA 1365
+ +D LL ED P + VH +I AE L V L L+
Sbjct: 1624 IKVDDLNDLL--ED-----SVEPII----------LVHEDIPMKTAEWLKVPCLSTRLI- 1665
Query: 1366 ESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLL 1425
+ ++M F E GQ E LT R+K+ILE Y EL+QNA+DA A+E F++
Sbjct: 1666 -NPENMGF------EQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMI 1718
Query: 1426 D--KSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFG 1483
D ++ ++L P MA GPAL+ FN+S F+ D I+R+G+ K + +G+FG
Sbjct: 1719 DMRRNMDIRENLLDPGMAACHGPALWSFNNSEFSDSDFINITRLGESLKRGEVDKVGKFG 1778
Query: 1484 LGFNCVYHFTDIPMFVSGENIVMFDPHASNLPG--ISPSHPGLRIKFA-GRKILEQFPDQ 1540
LGFN VYH TDIP+ +S E ++MFDP+ +++ S+PG++I ++ +K L +FP+Q
Sbjct: 1779 LGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDRSNPGIKINWSKQQKRLRKFPNQ 1838
Query: 1541 FSSLLH-FGCDL------QHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFS 1593
F + FGC L + + GTLFR RT A S++ Y D+ SL FS
Sbjct: 1839 FKPFIDVFGCQLPLAVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFS 1898
Query: 1594 EVVSETLLFLRNVKSI 1609
++F ++V S+
Sbjct: 1899 LCGHRLIIFTQSVNSM 1914
Score = 159 bits (403), Expect = 8e-37
Identities = 89/246 (36%), Positives = 148/246 (59%), Gaps = 12/246 (4%)
Query: 5 SPESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAG 64
+PE++ E GQ LT RI+ +L YP + + KEL+QNADDA AT S +D R +
Sbjct: 1666 NPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMD 1725
Query: 65 --DSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVY 122
++LL ++ GPAL ++N++ F++ DFI+I+++G S K G+ K G+FG+GFNSVY
Sbjct: 1726 IRENLLDPGMAACHGPALWSFNNSEFSDSDFINITRLGESLKRGEVDKVGKFGLGFNSVY 1785
Query: 123 HLTDLPSFVSGKYVVLFDPQGVYLPR--VSAANPGKRIDFT-GSSALSLYKDQFSPYC-A 178
H+TD+P +S +++++FDP ++ + +NPG +I+++ L + +QF P+
Sbjct: 1786 HITDIPIIMSREFMIMFDPNINHISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPFIDV 1845
Query: 179 FGCDM----QSPFA--GTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTL 232
FGC + ++P++ GTLFR R +A S++S Y DI S+ + G +
Sbjct: 1846 FGCQLPLAVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLI 1905
Query: 233 LFLKSV 238
+F +SV
Sbjct: 1906 IFTQSV 1911
Score = 71.6 bits (174), Expect = 3e-10
Identities = 42/153 (27%), Positives = 76/153 (49%), Gaps = 19/153 (12%)
Query: 363 GQAFCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPA 422
G+ FC+LPL ++TGL + +NG F V+SNR+ IW D R WN + ++ A
Sbjct: 2089 GEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIWKTDTKGR-------WNTTFMRHVIVKA 2141
Query: 423 FVHMLHGVKELLGPTDI----YYSLWPTGS-FEEPWSILVQQIYINICNA-----PVIYS 472
++ L +++L ++ YY++WP + +S++ Q Y +I + ++S
Sbjct: 2142 YLQALSVLRDLAISGELIDYTYYAVWPDPDVVHDDFSVICQGFYEDIAHGKGKDLTRVFS 2201
Query: 473 NLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQL 505
+ G WVS D+ + KD+ A ++
Sbjct: 2202 D--GSMWVSMKNVRFLDDSILQRKDVGSAAFKI 2232
Score = 62.8 bits (151), Expect = 1e-07
Identities = 52/179 (29%), Positives = 83/179 (46%), Gaps = 24/179 (13%)
Query: 1773 GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYLLENVVAPA 1832
G FC+LPL I TGLP H+N F ++SNR++IW +D G WN + +V+ A
Sbjct: 2089 GEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIW-KTDTKG------RWNTTFMRHVIVKA 2141
Query: 1833 YGRLLEKVA-LEIGP---CYLFFSLWPKTLGLEPWASVI-RKLYQFVAEFNLRVL-YTEA 1886
Y + L + L I Y ++++WP + SVI + Y+ +A + L +
Sbjct: 2142 YLQALSVLRDLAISGELIDYTYYAVWPDPDVVHDDFSVICQGFYEDIAHGKGKDLTRVFS 2201
Query: 1887 RGGQWISTKHAIFPDFSFPKADEL-----------IKALSGASLPVITLPQSLLERFME 1934
G W+S K+ F D S + ++ +K +L + LP S+ F E
Sbjct: 2202 DGSMWVSMKNVRFLDDSILQRKDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKVGFEE 2260
Score = 48.9 bits (115), Expect = 0.002
Identities = 36/147 (24%), Positives = 68/147 (45%), Gaps = 16/147 (10%)
Query: 2050 TNISFLSCQLLEKLLVKLLPVEWQHASLV-SWTPGIHGQ--PSLEWLQLLWNYLKAN-CD 2105
T + L+ + +L+ +++ W LV W P + PS+ WL+++W L + +
Sbjct: 954 TQLQLLNPERFARLIKEVMNTFWPGRELVVQWYPLSEDKHHPSISWLKMVWKNLYIHFSE 1013
Query: 2106 DLLMFSKWPILP-----VGDDC--LIQLKPNLNVIKNDGWSEKMSSLLVKV-----GCLF 2153
DL +F + P++P C LI+L+ VI +D ++ L + G +
Sbjct: 1014 DLTLFDEMPLIPRTPLDADQTCVELIRLRVPSVVILDDETEAQLPEFLADIVQKLGGIVL 1073
Query: 2154 LRPDLQLDHPKLECFVQSPTARGVLNV 2180
R D L HP ++ ++ SP +L +
Sbjct: 1074 KRLDTSLQHPLVKKYIHSPLPSAILQI 1100
>emb|CAE45964.1| hypothetical protein [Homo sapiens]
Length = 731
Score = 251 bits (642), Expect = 2e-64
Identities = 218/726 (30%), Positives = 336/726 (46%), Gaps = 66/726 (9%)
Query: 26 EVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSLSQWQGPALLAYND 85
++L YPEG +LKELIQNA+DAGAT V D + ++L S ++ +QGPAL YN+
Sbjct: 1 DILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAPYQGPALYVYNN 60
Query: 86 AVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVSGKYVVLFDP-QGV 144
AVFT +D+ I +I S K K GRFG+GFNSVYH+TD+P SG + + DP Q +
Sbjct: 61 AVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPHQTL 120
Query: 145 YLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCA-FGCDMQS----PFAGTLFRFPLRNA 199
+ P S + D S +S DQF+P+ FG ++ F GT FRFPLR
Sbjct: 121 FGPHESGQCWNLKDD---SKEISELSDQFAPFVGIFGSTKETFINGNFPGTFFRFPLR-- 175
Query: 200 DQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEPKPKKIHSC 259
S+LS Y + + +F + LLFLKSV + +YV +A +
Sbjct: 176 --LQPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQDVSLYVREADGTEKLVFR-- 231
Query: 260 SVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVRQVDRFYIVQ-TM 318
V+S + H + + P +T V V + + Q T
Sbjct: 232 -VTSSESKALKHERPNSIKILGTAISNYCKKTPSNNITCVTYHVNIVLEEESTKDAQKTS 290
Query: 319 ASASSRIGSFAITA---SKEYDIQLLPWASIAACIS---DNSLNNDVLRTGQAFCFLPLP 372
+ +G I++ S +++ +P IA +S D + +G+AFCFLPLP
Sbjct: 291 WLVCNSVGGRGISSKLDSLADELKFVPIIGIAMPLSSRDDEAKGATSDFSGKAFCFLPLP 350
Query: 373 ----VRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHM-L 427
TGL V ++GFF ++ NRR I + ++D+ ++WN L+ ++V A+ + L
Sbjct: 351 PGEESSTGLPVHISGFFGLTDNRRSIKW-RELDQWRDPAALWNEFLVMNVVPKAYATLIL 409
Query: 428 HGVKELLG--------PTDIYYSLWPTGS-FEEPWSILVQQIYINICNAPVIYSNLGGGR 478
+K L D+ Y LWP S + W +++ ++ + VIYS
Sbjct: 410 DSIKRLEMEKSSDFPLSVDVIYKLWPEASKVKVHWQPVLEPLFSELLQNAVIYSI--SCD 467
Query: 479 WVSPSEAFLH--DEKFTKSKDLSLALMQLGMPVVHLPNSLFDMLLKYNSS------KVIT 530
WV + + DE +K + L G + +P ++ D ++ ++ + +T
Sbjct: 468 WVRLEQVYFSELDENLEYTKTVLNYLQSSGKQIAKVPGNV-DAAVQLTAASGTTPVRKVT 526
Query: 531 PGTVRQFLRECESCNHLSRA-HKLLLLEYCLEDLVDDDVGKAAYNLPLLPLANGNFASFL 589
P VRQ LR+C HL A KL LLE+ L D ++ L LLPL NGNF F
Sbjct: 527 PAWVRQVLRKCA---HLGCAEEKLHLLEFVLSDQAYSEL----LGLELLPLQNGNFVPFS 579
Query: 590 E--ASKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSN---TNIALFSI 644
+ + + Y E L + R I ++ P+++ L A + T + L +
Sbjct: 580 SSVSDQDVIYITSAEYPRSLFPSLEGRFILDNLKPHLVAALKEAAQTRGRPCTQLQLLNP 639
Query: 645 HHFAHLFPVFMPDDWK-YKCKVFWDP--DSCQKPTSSWFVLFWQYLGKQ-SEILPLFKDW 700
FA L M W + V W P ++ P+ SW + W+ L SE L LF +
Sbjct: 640 ERFARLIKEVMNTFWPGRELIVQWYPFDENRNHPSVSWLKMVWKNLYIHFSEDLTLFDEM 699
Query: 701 PILPST 706
P++P T
Sbjct: 700 PLIPRT 705
Score = 247 bits (630), Expect = 4e-63
Identities = 216/757 (28%), Positives = 355/757 (46%), Gaps = 89/757 (11%)
Query: 1395 ILEMYADGPGTLFELVQNAEDAGASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCFNDS 1454
IL Y +G L EL+QNAEDAGA+EV FL D++QYGT ++ S +MA +QGPALY +N++
Sbjct: 2 ILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAPYQGPALYVYNNA 61
Query: 1455 VFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIVMFDPHASNL 1514
VFTP+D + I I + K + +GRFG+GFN VYH TD+P SG+ I M DPH L
Sbjct: 62 VFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPH-QTL 120
Query: 1515 PGISPSHPGLRIKFAGRKILEQFPDQFSSLLH-FGCD----LQHPFPGTLFRFPLRTAGV 1569
G S +K ++I E DQF+ + FG + FPGT FRFPLR
Sbjct: 121 FGPHESGQCWNLKDDSKEISE-LSDQFAPFVGIFGSTKETFINGNFPGTFFRFPLR---- 175
Query: 1570 ASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLHRVSR 1629
SQ+ +Y + V LF +F LLFL++V+ +S++++E G E +L+ RV+
Sbjct: 176 LQPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQDVSLYVREADGTE-KLVFRVTS 234
Query: 1630 ASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLSLSIDRDLPYKCQKILITEQGTH 1689
+ ES+ E + +++G + + KK + + Y I++ E+ T
Sbjct: 235 S---ESKALKHERPNSI------KILGTAISNYCKKTPSNNITCVTYHV-NIVLEEESTK 284
Query: 1690 GRNSHYWIMTECLGGGNVLKGTSEASTSNSHNFVPWACVAAYLNSVKHGEDLVDSAEVED 1749
W++ +GG + + S ++ FVP +A L+S +D A
Sbjct: 285 DAQKTSWLVCNSVGGRGI--SSKLDSLADELKFVPIIGIAMPLSS---RDDEAKGA---- 335
Query: 1750 DCLVSSDLFQFASLPMHPRENFEGRAFCFLPLP----ISTGLPAHVNAYFELSSNRRDI- 1804
+F G+AFCFLPLP STGLP H++ +F L+ NRR I
Sbjct: 336 ------------------TSDFSGKAFCFLPLPPGEESSTGLPVHISGFFGLTDNRRSIK 377
Query: 1805 WFGSDMTGGGRKRSDWNIYLLENVVAPAYGRL----LEKVALEIGPCY-----LFFSLWP 1855
W ++ + WN +L+ NVV AY L ++++ +E + + + LWP
Sbjct: 378 W--RELDQWRDPAALWNEFLVMNVVPKAYATLILDSIKRLEMEKSSDFPLSVDVIYKLWP 435
Query: 1856 KTLGLE-PWASVIRKLYQFVAEFNLRVLYTEARGGQWISTKHAIFP--DFSFPKADELIK 1912
+ ++ W V+ L+ + + V+Y+ + W+ + F D + ++
Sbjct: 436 EASKVKVHWQPVLEPLFSELLQ--NAVIYSIS--CDWVRLEQVYFSELDENLEYTKTVLN 491
Query: 1913 ALSGASLPVITLPQSLLERFMEICPS----LHFLKPKLLRTLLIRRKREFKDRDAMILTL 1968
L + + +P ++ S + + P +R +L R+ + + L
Sbjct: 492 YLQSSGKQIAKVPGNVDAAVQLTAASGTTPVRKVTPAWVRQVL-RKCAHLGCAEEKLHLL 550
Query: 1969 EYCLHDFEESMQFDTLGGLPLLPLADGSFTSIEMKGIGERV-YIARGDEYGLLRDSIPHQ 2027
E+ L D + L GL LLPL +G+F + V YI + L S+ +
Sbjct: 551 EFVLSD----QAYSELLGLELLPLQNGNFVPFSSSVSDQDVIYITSAEYPRSLFPSLEGR 606
Query: 2028 LVDCVIPKEVHRKLCYIAQT---DSTNISFLSCQLLEKLLVKLLPVEWQHASL-VSWTP- 2082
+ + + L AQT T + L+ + +L+ +++ W L V W P
Sbjct: 607 FILDNLKPHLVAALKEAAQTRGRPCTQLQLLNPERFARLIKEVMNTFWPGRELIVQWYPF 666
Query: 2083 -GIHGQPSLEWLQLLWNYLKAN-CDDLLMFSKWPILP 2117
PS+ WL+++W L + +DL +F + P++P
Sbjct: 667 DENRNHPSVSWLKMVWKNLYIHFSEDLTLFDEMPLIP 703
>emb|CAG09278.1| unnamed protein product [Tetraodon nigroviridis]
Length = 3392
Score = 251 bits (640), Expect = 3e-64
Identities = 268/1057 (25%), Positives = 442/1057 (41%), Gaps = 174/1057 (16%)
Query: 885 QFYKKHVFDRVGELQAEDRDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIGTLKCP 944
+FY++ VF+ +G + AE RD+++L + L I DLL + IPT G L+
Sbjct: 1210 RFYQQAVFNNLGAIDAETRDTLVLHAID------LNIKEIDDLLVSYPCIPTKAGPLQYI 1263
Query: 945 SVLYDPRNEEIYALLEDSDSFPSGV---FRESETLDIMRGLGLKTSVSP-DTVLESARCI 1000
L +P + + + G F + + + LG+ + P + + E A I
Sbjct: 1264 RKLVNPSGKVACLFELEEERLLGGTSNDFCSPKRIQRLMALGMASEDLPLEDIAEKAETI 1323
Query: 1001 EHLMHEDQQKAYLKGKVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSD 1060
+ D+ KAY K L ++ + N +
Sbjct: 1324 SSIWSTDRPKAYRFLKSLLDLMK-----------------------------KHMNECGE 1354
Query: 1061 IEKFWNDLQLISWCPVLVSPPFHSLPWPVVSSMVAPPKVVRPPNDLWLVSAGMRILDGEC 1120
W +++ + P P S + P + LVS +LD
Sbjct: 1355 DSSHWETIKMTKFLPAFC-------PGHTSSVTLERPTDIFNDKCSLLVSMTQPVLDHSN 1407
Query: 1121 ----SSTALLYCLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTG 1176
++ +L LG + P ++ +QL + + ++ VL + +A + +
Sbjct: 1408 LNMHNTDPVLTFLGVIDSPSPEIVLSQLQKSYEQSQSTGKAVLYK---IAYECYHFLNQY 1464
Query: 1177 MIGSDEIEIVKAVLEGCRWIWVGDGFATSDEVVLDGPLHLAPYIRVIPVDLAVFKNLFLE 1236
+ GS + +I V F + V + PY+ V+P FK L+
Sbjct: 1465 LAGSVSPSSIHQAAHSFPFILVDSTFVHVNCVAENEQFDAKPYLHVLPSSFVHFKTLWGC 1524
Query: 1237 LGIREFLQPSDYVNILFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYLHGQKVQL---YL 1293
+G+++ + +L + ++ GS PL +++ + I++ + L +K + +
Sbjct: 1525 VGVKKSFTIQQFHTVLQELHSRYGSQPLSQRDLSICLTILN---KGILEAEKETVGDCLV 1581
Query: 1294 PDVSGRLFLAGDLVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEK 1353
P+ G L A +LVYND+PW+ P G VT H NI+ A
Sbjct: 1582 PNEDGVLQHARELVYNDSPWM---PVPSG-------VT---------LCHRNIARAAALH 1622
Query: 1354 LGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNA 1413
G+++ R L S +S A F Q E LT R+K+I+ Y L EL+QNA
Sbjct: 1623 FGIKTTRHDTLLNSEVK---SISPFAFQFEQQEQLTVRIKNIISAYPSKKDILKELLQNA 1679
Query: 1414 EDAGASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKL 1473
+DA A+E+ F+ DK Q+G QGPAL FN+ VF+ DL I ++G+ K
Sbjct: 1680 DDAEATEIHFVWDKRQHGVEKTFGERWNQLQGPALCVFNNKVFSNADLKGIQQLGEGGKH 1739
Query: 1474 EKAFAIGRFGLGFNCVYHFTDIPMFVSGENIV-MFDPHASNLPGISPSHPGLRIKFAGRK 1532
IG++G+GFN VYH TD P ++G++++ + DP+ + S P G K
Sbjct: 1740 STRGKIGKYGVGFNSVYHLTDCPSILTGDSLLCISDPNQKYIECYSDKAPA----GIGYK 1795
Query: 1533 ILEQFPDQFSSLLHFGCDLQHPFP---GTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLF 1589
+ ++F + ++ + + L FP GT+FR PLRT +A+ S I + T D+R L
Sbjct: 1796 LDDKFKNMYADV--YQSFLPDRFPLHEGTMFRLPLRTFFMATSSNISDKEVTDSDMRMLC 1853
Query: 1590 AAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFNFF 1649
+A S +LFL+N+ I + HE+ ++ GS + +F
Sbjct: 1854 SALSADSDGLILFLKNITKIEV-------HEI-------------NDHGSKPNRTIFTVE 1893
Query: 1650 KEDRLVGMNRAQ-FLKKLSLSIDRDLPYKCQKILI-TEQGTHGRNSHYWIMTECLGGGNV 1707
K ++ + F++ ++ QK++ T T + W++ E G
Sbjct: 1894 KSIAPTSRDQKEAFVRLRQDALKSHTVVAPQKVIYETRVSTSDKKETTWMIAEQFGS--- 1950
Query: 1708 LKGTSEASTSNSHNFVPWACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMHP 1767
+ T E+ + +P A VAA + S F+ +S + P
Sbjct: 1951 YQNTGESEMLSDQ--LPQAAVAARM----------------------SITFRQSSSFLSP 1986
Query: 1768 RENFEGRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIYLLEN 1827
F G AFC LPLP TGLP H+NA FE+ S R+++W G +S WN +L EN
Sbjct: 1987 SVEFTGEAFCSLPLPGKTGLPVHINANFEVDSARKNLW----KEDGQSAKSGWNEFLKEN 2042
Query: 1828 VVAPAYGRLLEKVALEIG-------------PCYLFFSLWPKTLG--LEPWASVIRKLYQ 1872
VAP Y LL ++ IG YL F WP + W ++I +Y+
Sbjct: 2043 -VAPLYADLLLYISSNIGNKKVPLPYRFHLNSMYLCF--WPVVSKDVSQDWQNMIHGVYR 2099
Query: 1873 FVAEFNLR---VLYTEA--RGGQWISTKHAIFPDFSF 1904
+ + L+ VL T A RG Q IF +FSF
Sbjct: 2100 SIQKRGLKVIPVLRTSAFVRGNQ-------IFKEFSF 2129
Score = 239 bits (611), Expect = 6e-61
Identities = 174/541 (32%), Positives = 270/541 (49%), Gaps = 43/541 (7%)
Query: 6 PESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHA-- 63
PE + +E GQ+ +TRRI+ +L Y E + KELIQNA+DAGA S +D R+H
Sbjct: 650 PELVGIEQCGQSEPITRRIKNILNEYDEEGDIFKELIQNAEDAGAQQCSFLVDFRTHKYN 709
Query: 64 GDSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYH 123
+ L+ +S QGP L A+N+ F +DD+ +I ++G +SK + K G+FG+GFN+VYH
Sbjct: 710 PEELIDPDMSLCQGPCLWAFNNETFKDDDWTNIVRVGSASKETKLEKIGKFGLGFNTVYH 769
Query: 124 LTDLPSFVSGKYVVLFDPQGVYLPR--VSAANPGKRIDFTGSSALSLYKDQFSPY-CAFG 180
+TD+PS +SG +++ DP +L +NPG R+D + + QF PY F
Sbjct: 770 VTDIPSILSGNRLLILDPNVTHLKTHIKQKSNPGIRLDLSQLRLFKCFPGQFGPYDRIFD 829
Query: 181 CDM--QSPFAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSV 238
CD Q P+ GTL R P R ++A S++S++ Y DI S L E LLFL+S+
Sbjct: 830 CDFAKQKPYEGTLIRLPFRTEEEALTSEISKRVYYKSDIVSFQECLAENSKSHLLFLRSI 889
Query: 239 --LCIEMYVWDAGEP----KPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDA-- 290
L ++ DA P + K I + S ++V+ I +R + + +S +D
Sbjct: 890 SSLALQNIPKDASTPPRDDEIKTIRNVSRTTVTTVRIPNRAHMSKQQESEKLLMSLDVKA 949
Query: 291 -FPLEFVTEAVRGV----ETVRQVDRFYIVQTMASASSRIGSFAITASKEYDIQLLPWAS 345
+++ T + + +V +V + + + S A+ +K+ LP
Sbjct: 950 NSVIDYCTADIVNITSQQSSVTEVQSWLLYSCFGTQQS--VKMALQENKQAKFS-LPMGG 1006
Query: 346 IAACISDNSLNNDVLR-----TGQAFCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYGDDM 400
+A + N+ N + +G+AFCFLPL + TGL V +NG F V+SNR+G+W
Sbjct: 1007 VAVPLQMNAKTNKLTTMEAEFSGEAFCFLPLSIHTGLPVSINGTFAVTSNRKGLW----- 1061
Query: 401 DRSGKVRSIWNRLLLEDLVAPAFVHMLHGVKELLGPTDI----YYSLWP-TGSFEEPWSI 455
SG V+ WN+ LL+D V A+V L +KE+ + Y++ WP E +
Sbjct: 1062 -ESG-VKWDWNKALLQDPVVTAYVTALLVLKEMAQMKQLEPYSYHTFWPRREKVSEHFKS 1119
Query: 456 LVQQIYINICNAPVIYSNL--GGGRWVSPSEAFLHDEKFTKSKDLSLALMQLGMPVVHLP 513
LV Y I P L G W S S A E + +D+ +Q+ V P
Sbjct: 1120 LVDAFYSRI-GQPSSGLELFHDGELWCSMSSAIFLHECIEEDEDVGALAVQVCKKHVKTP 1178
Query: 514 N 514
N
Sbjct: 1179 N 1179
Score = 233 bits (594), Expect = 6e-59
Identities = 290/1161 (24%), Positives = 482/1161 (40%), Gaps = 204/1161 (17%)
Query: 8 SIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSL 67
S F F Q LT RI+ ++ YP +LKEL+QNADDA AT + D+R H +
Sbjct: 1642 SPFAFQFEQQEQLTVRIKNIISAYPSKKDILKELLQNADDAEATEIHFVWDKRQHGVEKT 1701
Query: 68 LSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDL 127
+Q QGPAL +N+ VF+ D I ++G KH K G++GVGFNSVYHLTD
Sbjct: 1702 FGERWNQLQGPALCVFNNKVFSNADLKGIQQLGEGGKHSTRGKIGKYGVGFNSVYHLTDC 1761
Query: 128 PSFVSG-KYVVLFDPQGVYLPRVSAANP---GKRIDFTGSSALSLYKDQFSPYCAFGCDM 183
PS ++G + + DP Y+ S P G ++D ++Y D Y +F D
Sbjct: 1762 PSILTGDSLLCISDPNQKYIECYSDKAPAGIGYKLD---DKFKNMYAD---VYQSFLPDR 1815
Query: 184 QSPFAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEM 243
GT+FR PLR A+ S +S + T D+ + L + +LFLK++ IE+
Sbjct: 1816 FPLHEGTMFRLPLRTFFMATSSNISDKEVTDSDMRMLCSALSADSDGLILFLKNITKIEV 1875
Query: 244 YVWDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGV 303
+ + KP + S++ + ++A +RL + + V A P + + E V
Sbjct: 1876 HEINDHGSKPNRTIFTVEKSIAPTSRDQKEAFVRLRQDALKSHTVVA-PQKVIYET--RV 1932
Query: 304 ETVRQVDRFYIVQTMASASSRIGSFAITASKEYDIQLLPWASIAACI------SDNSLNN 357
T + + +++ + + GS+ T E LP A++AA + S + L+
Sbjct: 1933 STSDKKETTWMI------AEQFGSYQNTGESEMLSDQLPQAAVAARMSITFRQSSSFLSP 1986
Query: 358 DVLRTGQAFCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLED 417
V TG+AFC LPLP +TGL V +N FEV S R+ +W D +S WN L E+
Sbjct: 1987 SVEFTGEAFCSLPLPGKTGLPVHINANFEVDSARKNLWKEDGQ----SAKSGWNEFLKEN 2042
Query: 418 LVAPAFVHMLHGVKELLGP-----------TDIYYSLWPTGS--FEEPWSILVQQIYINI 464
VAP + +L + +G +Y WP S + W ++ +Y +I
Sbjct: 2043 -VAPLYADLLLYISSNIGNKKVPLPYRFHLNSMYLCFWPVVSKDVSQDWQNMIHGVYRSI 2101
Query: 465 CN-----APVIYSN--LGGGR--------WVSPSEAFLHDEKFTK---SKDLSLALMQLG 506
PV+ ++ + G + W + +E L + + L+ L LG
Sbjct: 2102 QKRGLKVIPVLRTSAFVRGNQIFKEFSFDWCNITETELPKRPYLMHPFNNGLNTILEDLG 2161
Query: 507 MPVVHLPNSLFDMLLKYNSS----KVITPGTVRQFLRE--------CESCNHLSRAHKLL 554
M +V + + + S+ K +TP TV+ FLRE + L H L+
Sbjct: 2162 MILVPFSAEMQKVWDSFKSAGVDVKEVTPTTVQNFLREIPLNDPDQTDEDLPLPITHTLI 2221
Query: 555 --------LLEYCLEDL------VDDDVGKAAYNLPLLPLANGNFASFLEASKGIPYFIC 600
LL +CL+D + D+ ++ +PLL L K + F C
Sbjct: 2222 RDESKCAQLLSFCLQDFERDLDSLTDESSRSFDGIPLL----------LTRDKMLRVFTC 2271
Query: 601 DELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMSSNTNIALFSIHHFAHL---------F 651
D P +++ G+ ++ A F +F H+
Sbjct: 2272 DS-------------------PRMISAFEGLFLTYEEQFADFRT-NFTHIQVLQALNLVK 2311
Query: 652 PVFMPDDWKY----------KCKVFWDPDS----CQKPTSSWFVLFWQYLGK-------- 689
+ +P+ Y C++ DPDS ++ T W +FW++L
Sbjct: 2312 TLTIPEAQPYLQPVAQSLLQDCEL--DPDSGLHVPKQTTLDWLKVFWRFLTSDIKLETSD 2369
Query: 690 -------QSEILPLFKDWPILPSTSGHLLRPSRQL--------KMINGSTLSDTVQDILV 734
S++ LF D+ +LP L S++L K+I+ + SD + DIL
Sbjct: 2370 DEKKSLIMSDLRTLFSDFCVLPVVCPRL--DSKRLLTAVGTMPKVIHFLSTSD-ILDILC 2426
Query: 735 KIGCHILKPGYVVEHPDLF---SYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEERN 791
++G L + H ++ + + VLE + + S FS L +
Sbjct: 2427 QLGFMKLDRSSLDNHISSIMRNEFMNLNDRSAVLEQLCDINPS------QFSRLSTQHLK 2480
Query: 792 ELRRFLLDPQWYVGHSMDEFNIRF-CRRLPIYQVYHREPTQ----DSQFSDLENPRKYLP 846
EL+ FL Q V D+ N + + LP++ H E + + F + + P
Sbjct: 2481 ELQSFL---QEGVSRCEDKPNYQSKLKSLPLFLTVHDERVRIDGPNDVFVLVSKFSREFP 2537
Query: 847 PLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDSI 906
L F L + I+ + E L+ ++ + ++ K + V L E +
Sbjct: 2538 QL----FRLSDSKCILLQNTLENYSLATILNIQALSDLDYFMKFILPDVHTL-PEPQLLQ 2592
Query: 907 MLSVLQNLPL---LSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLEDSD 963
L ++ +LP + +I L+ +K I + GTL+ S YD + A+L
Sbjct: 2593 CLKLVLSLPCDTNYYMHKDAIASSLKTVKLIRSSQGTLETASYYYDESVKLYKAMLPQER 2652
Query: 964 SFPSGVFRE---------SETLDIMRGLGLKTSVSPDTVLESARCIEHLMHEDQQKAYLK 1014
P + E + +++R LG++ VS D + + A+ +E D LK
Sbjct: 2653 FVPESFWAELCHEKPQMMNHPRELLRELGMRHVVSADDIRQFAKQLESEASGDFPFETLK 2712
Query: 1015 GKVLFSYLEVNALKWLPDKFD 1035
K + E AL ++ +K D
Sbjct: 2713 DKSSLVFQE--ALNFVTNKAD 2731
Score = 229 bits (585), Expect = 7e-58
Identities = 210/745 (28%), Positives = 331/745 (44%), Gaps = 114/745 (15%)
Query: 1194 RWIWVGDGFATSDEVVLDGP--LHLAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNI 1251
RW+W F + ++VL+ P L L+ YI +P + FK L G+R L + V I
Sbjct: 483 RWLWNHGRFVSPQDLVLEYPPNLDLSSYISKVPEEFLSFKKLLQRFGLRTTLSDEEIVGI 542
Query: 1252 LFRMANKKGSSPLDTQEIRAVMLIVHHLAEVYLHGQKVQLYLPDVSGRLFLAGDLVYNDA 1311
L R+V V + + ++++ + ++ L+ V D
Sbjct: 543 L-----------------RSVQQTVQERRPPFANPSEIKVSI-EILNWLWREKKTVQEDI 584
Query: 1312 PWLLGSEDPDGSFGNAPSVTW--------NAKRTVQK---FVHGNISNDVAEKLGVRSLR 1360
P + +E +F + +V + N ++ Q+ +H I AE L + L
Sbjct: 585 PVPVHTEGGQYTFKPSSTVVFCDVSKKGMNELKSSQEEMFVIHEEIPKAAAEWLNISFLS 644
Query: 1361 RMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLF-ELVQNAEDAGAS 1419
+L D G+ E GQ E +T R+K+IL Y D G +F EL+QNAEDAGA
Sbjct: 645 THIL----DPELVGI----EQCGQSEPITRRIKNILNEY-DEEGDIFKELIQNAEDAGAQ 695
Query: 1420 EVIFLLD--KSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAF 1477
+ FL+D +Y ++ P+M+ QGP L+ FN+ F D I R+G SK K
Sbjct: 696 QCSFLVDFRTHKYNPEELIDPDMSLCQGPCLWAFNNETFKDDDWTNIVRVGSASKETKLE 755
Query: 1478 AIGRFGLGFNCVYHFTDIPMFVSGENIVMFDPHASNLPG--ISPSHPGLRIKFAGRKILE 1535
IG+FGLGFN VYH TDIP +SG +++ DP+ ++L S+PG+R+ + ++ +
Sbjct: 756 KIGKFGLGFNTVYHVTDIPSILSGNRLLILDPNVTHLKTHIKQKSNPGIRLDLSQLRLFK 815
Query: 1536 QFPDQFSSLLH-FGCDL--QHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAF 1592
FP QF F CD Q P+ GTL R P RT A S+I K VY D+ S
Sbjct: 816 CFPGQFGPYDRIFDCDFAKQKPYEGTLIRLPFRTEEEALTSEISKRVYYKSDIVSFQECL 875
Query: 1593 SEVVSETLLFLRNVKSISI--FLKEGT----GHEMRLLHRVSRASLGESEIGSAEVQDVF 1646
+E LLFLR++ S+++ K+ + E++ + VSR ++ I +
Sbjct: 876 AENSKSHLLFLRSISSLALQNIPKDASTPPRDDEIKTIRNVSRTTVTTVRIPNR------ 929
Query: 1647 NFFKEDRLVGMNRAQFLKKLSLSID----RDLPYKCQKIL-ITEQGTHGRNSHYWIMTEC 1701
M++ Q +KL +S+D + Y I+ IT Q + W++ C
Sbjct: 930 --------AHMSKQQESEKLLMSLDVKANSVIDYCTADIVNITSQQSSVTEVQSWLLYSC 981
Query: 1702 LGGGNVLKGTSEASTSNSHNFVPWACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFA 1761
G +K + + + +P VA L + + + + E E
Sbjct: 982 FGTQQSVKMALQENKQAKFS-LPMGGVAVPL-QMNAKTNKLTTMEAE------------- 1026
Query: 1762 SLPMHPRENFEGRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWN 1821
F G AFCFLPL I TGLP +N F ++SNR+ +W + DWN
Sbjct: 1027 ---------FSGEAFCFLPLSIHTGLPVSINGTFAVTSNRKGLWESG-------VKWDWN 1070
Query: 1822 IYLLENVVAPAYGRLL----EKVALEIGPCYLFFSLWPKTLGL-EPWASVIRKLYQFVAE 1876
LL++ V AY L E ++ Y + + WP+ + E + S++ Y + +
Sbjct: 1071 KALLQDPVVTAYVTALLVLKEMAQMKQLEPYSYHTFWPRREKVSEHFKSLVDAFYSRIGQ 1130
Query: 1877 --FNLRVLYTEARGGQWISTKHAIF 1899
L + + G W S AIF
Sbjct: 1131 PSSGLELFHD---GELWCSMSSAIF 1152
Score = 67.8 bits (164), Expect = 4e-09
Identities = 81/369 (21%), Positives = 153/369 (40%), Gaps = 39/369 (10%)
Query: 675 PTSSWFVLFWQYLGKQSEILPLFKDWPILPSTSGHLLRPSRQLKMINGSTL--------- 725
P +W FW++L + L F P++P + +P ++ +TL
Sbjct: 2 PPLNWLQDFWKFLNANFKELSNFHGMPLIPVSPVSADQPVSLSRLQKNTTLIFHKNKENT 61
Query: 726 -SDTVQDILVKIGCHILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSS 784
D++ +++ K+G ++K + H DL SY+ + VL+ + N E M S+
Sbjct: 62 LPDSMAELVNKVGGTVVKGTEWLWHSDLDSYVLPPSPKSVLKVLMNLHY--EGMIGKLSA 119
Query: 785 LIAEERNELRRFLLDPQWYVGHSMDEFNIRFCRRLPIYQVYH--REPTQDSQ----FSDL 838
+ EL+ +L + S+ I F +LP++Q P Q Q DL
Sbjct: 120 APHRAKEELKDYLCRLE-----SVSGAKIEFLLKLPLFQTMKGAHAPAQSKQALLLICDL 174
Query: 839 ENPRKYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHV-FDRVGE 897
+ P ++ P + +V+ + + L V + A+ V + G
Sbjct: 175 KVPTEFPLP-----------DSVVQCATEADRRLLLLLKVRLLDTAEAAGLLVDCIKKGA 223
Query: 898 LQAEDRDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYA 957
L+AE+ +M+ +LQ+ +L ++ ++ + L+FI V G K S +DP NE A
Sbjct: 224 LKAEETKKVMVWILQHGDVLFSQNQCLKRKCKELRFI-QVNGCTKATSSFFDPTNETFKA 282
Query: 958 LLEDSDSFPSGVFRESETLDIMRGLGL---KTSVSPDTVLESARCIEHLMHEDQQKAYLK 1014
+ P + E L + LGL + V P+ +L +A I+ + + Q+ +
Sbjct: 283 IFGSELFPPPSYTKTPEMLKSLTDLGLINREGDVPPEHLLHAATLIDQSVGDSSQEVTKR 342
Query: 1015 GKVLFSYLE 1023
+ L+
Sbjct: 343 ACAFLNMLD 351
Score = 54.3 bits (129), Expect = 5e-05
Identities = 54/209 (25%), Positives = 97/209 (45%), Gaps = 29/209 (13%)
Query: 2088 PSLEWLQLLWNYLKANCDDLLMFSKWPILPVG------DDCLIQLKPNLNVI----KNDG 2137
P L WLQ W +L AN +L F P++PV L +L+ N +I K +
Sbjct: 2 PPLNWLQDFWKFLNANFKELSNFHGMPLIPVSPVSADQPVSLSRLQKNTTLIFHKNKENT 61
Query: 2138 WSEKMSSLLVKVGCLFLRPDLQLDHPKLECFVQSPTARGVLNVFLAVAGEPQKIEGIFTD 2197
+ M+ L+ KVG ++ L H L+ +V P+ + VL V + + E + G +
Sbjct: 62 LPDSMAELVNKVGGTVVKGTEWLWHSDLDSYVLPPSPKSVLKVLMNLHYE--GMIGKLSA 119
Query: 2198 ASDGELHELRSFILQSKWFSEEQIDRSHVETIKHLPMFESYK-------SRKLVSLIKPI 2250
A EL+ ++ + E + + +E + LP+F++ K S++ + LI +
Sbjct: 120 APHRAKEELKDYLCRL-----ESVSGAKIEFLLKLPLFQTMKGAHAPAQSKQALLLICDL 174
Query: 2251 KWLGPTGVGEDLLNDSFIRTESDMERVIM 2279
K PT E L DS ++ ++ +R ++
Sbjct: 175 K--VPT---EFPLPDSVVQCATEADRRLL 198
>ref|XP_586753.1| PREDICTED: similar to sacsin, partial [Bos taurus]
Length = 2688
Score = 240 bits (612), Expect = 5e-61
Identities = 274/1037 (26%), Positives = 433/1037 (41%), Gaps = 168/1037 (16%)
Query: 843 KYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAED 902
K L +++P + +G E + ++ +L + + QF+ + F + E++AE
Sbjct: 1293 KNLCAVELPSSVKLGFE----EAGCKQILLENTFS-----ERQFFSEVFFPNIQEIEAEL 1343
Query: 903 RDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIG--TLKCPSVLYDPRNEEIYALLE 960
RD +M VL +++ S +LR IP + L PS L P + L +
Sbjct: 1344 RDPLMNFVLNE----KVDEFS--GILRVTPCIPCSLEGHPLVLPSRLIHPEGR-VAKLFD 1396
Query: 961 DSDS-FPSGVFRESETLDIMRGL---GL-KTSVSPDTVLESARCIEHLMHEDQQKAYLKG 1015
D FP G ++ I+ L G+ K + D +LE A + + D A L+
Sbjct: 1397 TKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAESVAEINKSDHGAACLRS 1456
Query: 1016 KVLFSYLEVNALKWLPDKFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCP 1075
+L S + D+K + R+ ++ + F Q I + P
Sbjct: 1457 SILLSLI------------DEK--------------LKIRDPRA--KDFAATYQTIPFLP 1488
Query: 1076 VLVSPPFHSLPWPVVSSMVAPPKVVRPPNDLWL------VSAGMRILDGE------CSST 1123
L P SL W S P+ + DL++ V IL+ C S
Sbjct: 1489 FLTKPAGFSLDWKGNSFK---PETMFAATDLYIAEHQDIVCLLQPILNENSHSFRGCGSV 1545
Query: 1124 ALLY--CLGWMCPPGGGVIAAQLLELGKNNEIVTDQVLRQELALAMPRIYSILTGMIGSD 1181
L LG + P ++ QL E+ K+ V D + + + + M+ +D
Sbjct: 1546 PLAVKEFLGLLRKPTVELVVNQLREVAKS---VDDGITLYQENITNACYKYLHEAMMQND 1602
Query: 1182 EIEI-VKAVLEGCRWIWVGDGFATSDEVVLDGPLHLAPYIRVIPVDLAV-FKNLFLELGI 1239
+ V L+ +I V + + S++V APY+ +P F+ LF +G+
Sbjct: 1603 STKTAVTEKLKTFSFILVENAYVNSEKVAFHLNFEAAPYLYQLPNKYKNNFRELFESVGV 1662
Query: 1240 REFLQPSDYVNILFRMANKKGSSPLDTQEIR--------AVMLIVHHLAEVYLHGQKVQL 1291
R+ D+ +L +A +K + + + + + ++ + + +
Sbjct: 1663 RQSFTVEDFALVLESIAQEKETKQVTEENFQLCRRIISEGIWSLIREKKQEFCEKNYGHI 1722
Query: 1292 YLPDVSGRLFLAGDLVYNDAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVA 1351
LPD + +L A L YND PW+ K + K+ H +I +VA
Sbjct: 1723 LLPDTNLKLLPAKSLCYNDCPWI------------------KVKDSTVKYCHADIPREVA 1764
Query: 1352 EKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQ 1411
KLG R L A ++ F G+ FGQ E LT+R+K IL Y L EL+Q
Sbjct: 1765 VKLGAVPKRHKALERYASNVCFTTLGSE--FGQKEKLTSRIKSILNAYPSEKEMLKELLQ 1822
Query: 1412 NAEDAGASEVIFLLDKSQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQES 1471
NA+DA A+E+ F+ D Q+ + + A QGPAL +N+ FT D+ I +G+ +
Sbjct: 1823 NADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGRGT 1882
Query: 1472 KLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIV-MFDPHASNLPGISPSHPGLRIKFAG 1530
K G++G+GFN VYH TD P F+SG +I+ +FDPHA PG + PG +
Sbjct: 1883 KEGNPCKTGQYGVGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSVSPGRMFRDLD 1942
Query: 1531 RKILEQFPDQFSSLL--HFGCDLQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSL 1588
QF D L HF D T+FRFPLR A +A S+I + V++L
Sbjct: 1943 ADFRTQFSDVLDLYLGTHFKLD-----NCTMFRFPLRNAEMAKVSEISSVPSSDRMVQNL 1997
Query: 1589 FAAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVFNF 1648
+E L+FL +++ ISI + + +L+ V N
Sbjct: 1998 LDKLRSDGAELLMFLNHMEKISICEIDKATGALNVLYSVKG-----------------NI 2040
Query: 1649 FKEDRLVGMNRAQFLKKL--SLSIDRDLPYKCQKILITEQGTHGRNSHYWIMTECLGGGN 1706
DRL R QF + S++ R LP + +Q T Y + TE
Sbjct: 2041 TDGDRL---KRKQFHASVIDSVTKKRQLP-----DIPVQQVT------YTMDTE------ 2080
Query: 1707 VLKGTSEASTSNSHNFVPW-ACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPM 1765
SE S ++ W C + +S+ V SA D LF +
Sbjct: 2081 ----DSEGSLTS------WLICNRSGFSSMDKVSKSVVSAHKNQDI----TLFPRGGVAA 2126
Query: 1766 HPRENFE--GRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGRKRSDWNIY 1823
N++ R FCFLPL + TGLP HVN +F L S RR++W + G RSDWN
Sbjct: 2127 CITHNYKKPHRVFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVG---VRSDWNSS 2183
Query: 1824 LLENVVAPAYGRLLEKV 1840
L+ ++APAY LL ++
Sbjct: 2184 LMTALIAPAYVELLAQL 2200
Score = 231 bits (588), Expect = 3e-58
Identities = 140/422 (33%), Positives = 215/422 (50%), Gaps = 13/422 (3%)
Query: 13 DFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
+FGQ LT RI+ +L YP +LKEL+QNADDA AT + D R H D +
Sbjct: 1792 EFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKW 1851
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+ QGPAL YN+ FTEDD I +G +K G KTG++GVGFNSVYH+TD PSF+S
Sbjct: 1852 APLQGPALCVYNNQPFTEDDVRGIQNLGRGTKEGNPCKTGQYGVGFNSVYHITDCPSFIS 1911
Query: 133 GKYVV-LFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFAGTL 191
G ++ +FDP Y P ++ +PG+ + + + D Y + + T+
Sbjct: 1912 GNDILCIFDPHARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGTHFKLDN---CTM 1968
Query: 192 FRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDAGEP 251
FRFPLRNA+ A S++S + + ++ +L +G L+FL + I + D
Sbjct: 1969 FRFPLRNAEMAKVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATG 2028
Query: 252 KPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFVTEAVRGVETVRQVDR 311
++S + D + +Q + S+ ++ P++ VT + ++ +
Sbjct: 2029 ALNVLYSVKGNITDGDRLKRKQFHASVIDSVTKKRQLPDIPVQQVTYTMDTEDSEGSLTS 2088
Query: 312 FYIVQTMA-SASSRIGSFAITASKEYDIQLLPWASIAACISDNSLNNDVLRTGQAFCFLP 370
+ I S+ ++ ++A K DI L P +AACI+ N + + FCFLP
Sbjct: 2089 WLICNRSGFSSMDKVSKSVVSAHKNQDITLFPRGGVAACITHN-----YKKPHRVFCFLP 2143
Query: 371 LPVRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLEDLVAPAFVHMLHGV 430
L + TGL VNG F + S RR +W D+ VRS WN L+ L+APA+V +L +
Sbjct: 2144 LSLETGLPFHVNGHFALDSARRNLWRDDN---GVGVRSDWNSSLMTALIAPAYVELLAQL 2200
Query: 431 KE 432
K+
Sbjct: 2201 KK 2202
Score = 225 bits (573), Expect = 2e-56
Identities = 269/1032 (26%), Positives = 445/1032 (43%), Gaps = 130/1032 (12%)
Query: 637 TNIALFSIHHFAHLFPVFMPDDWKYK-CKVFWDP--DSCQKPTSSWFVLFWQYLGKQ-SE 692
T + L + FA L M W + V W P + + P+ SW + W++L SE
Sbjct: 4 TQLQLLNTDRFARLIKEVMNTFWPGRELIVQWYPCDEDRKHPSVSWLRMVWKHLYVHFSE 63
Query: 693 ILPLFKDWPILP-------STSGHLLRPSRQLKMI----NGSTLSDTVQDILVKIGCHIL 741
L LF + P++P T L+R +I + + L + + D++ K+G +L
Sbjct: 64 DLTLFDEMPLIPRTPLEEGQTCVELIRLRAPSLVILDDESEAQLPEFLADVVQKLGGIVL 123
Query: 742 KP-GYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEERNELRRFLLDP 800
K ++HP + Y+ + + VL + + + +SL+ ++ LR+FL +
Sbjct: 124 KKLDASIQHPLIKKYIHLPSPSAVLHIMEKM--PLQKLCNQVASLLPTHKDALRKFLANL 181
Query: 801 QWYVGHSMDEFNIRFCRRLPIYQVYHREPTQD-SQFSDLENPRKYLPPLDVPEFILVGIE 859
E R + L I++ + +Q S ++ L+ R P +P + + I
Sbjct: 182 T-----ESSEKEKRIIQELTIFKRINHSSSQGLSSYTRLKGCRVLHPAATLPAGLRLSIS 236
Query: 860 FIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAEDRDS-IMLSVLQNLPLLS 918
+V SS+ L+ VE++ K + D +++ + ++L VL+NL L
Sbjct: 237 -VVDSSDEATIRLANLLKVEKVRTTSCLKLILKDIESTFYSQEEVTHLVLWVLENLSSLK 295
Query: 919 LEDASIRDLLRNLKFIPTVIGTLKCPSVLYDPRNEEIYALLEDSDS--FPSGVFRESETL 976
E+ ++ D L LKFI G L S L+DP E + L D + FP F + L
Sbjct: 296 SENPNVLDWLTPLKFIQLPPGRLVMASELFDPDIEVLKDLFYDEEEACFPPSAFTSPDIL 355
Query: 977 DIMRGLGLKT--SVSPDTVLESARCIEHLMHED--QQKAYLKGKVLFSYLEVNALKWLPD 1032
+R +GLK S+ V++ A+ IE L Q LK
Sbjct: 356 HSLRQIGLKNEASLKEKDVVQVAKKIEALQASSCPNQDTLLK------------------ 397
Query: 1033 KFDDKKGAVNRILSQAATAFRSRNTKSDIEKFWNDLQLISWCPVLVSPPFH---SLPWPV 1089
K + +L++ S K+ ++K I W P P + SL W
Sbjct: 398 ----KARTLLLVLNKNPALLHSCEGKATLKK-------IKWVPACKERPPNYPGSLVWKG 446
Query: 1090 -VSSMVAPPKVVRPPNDLWLVSAGMRILDGECSSTALLYCLGWMCPPGGGVIAAQLLELG 1148
+ + APP + + + LV + + ++ E L LG + PG I A L
Sbjct: 447 DLCELCAPPDMCDAAHAI-LVGSSLPLV--ESVHVNLEKALGILTKPG---INAVLKHFK 500
Query: 1149 KNNEIVTDQVLRQELALAMPRIYSILTGMIGSDEIEIVKAVLEGCR--WIWVGDGFATSD 1206
+ T + E I + G + D + K + W+W G F
Sbjct: 501 IVVDWYTSKTFSDEDYYQFQHILLEIYGFM-HDHLNEGKDAFRALKFPWVWTGKKFCPLA 559
Query: 1207 EVVLDGPLH---LAPYIRVIPVDLAVFKNLFLELGIREFLQPSDYVNILFRMANKKGSSP 1263
+ V+ P H L PY+ +P +A F LF G E L +D+++++ + K
Sbjct: 560 QAVIK-PFHDLDLQPYLHSVPKTMAKFHQLFKACGSIEELT-ADHISMVIQKVYLKSDQD 617
Query: 1264 LDTQEIRAVMLIVHHLAEVYLHGQ-------KVQLYLPDVSGRLFLAG-------DLVYN 1309
L QE + + ++ ++ Q V ++ +L + D+ +
Sbjct: 618 LSDQESKQNLHLMLNIIRWLYSNQIPASPNTPVPIHHSKNPSKLIMKPIHECCYCDIKVD 677
Query: 1310 DAPWLLGSEDPDGSFGNAPSVTWNAKRTVQKFVHGNISNDVAEKLGVRSLRRMLLAESAD 1369
D LL ED P + VH +I AE L V L L+ + +
Sbjct: 678 DLNDLL--ED-----SVEPII----------LVHEDIPMKTAEWLKVPCLSTRLI--NPE 718
Query: 1370 SMNFGLSGAAEAFGQHEALTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLD--K 1427
+M F E GQ E LT R+K+ILE Y EL+QNA+DA A+E F++D +
Sbjct: 719 NMGF------EQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRR 772
Query: 1428 SQYGTSSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFN 1487
+ ++L P MA GPAL+ FN+S F+ D I+R+G+ K + +G+FGLGFN
Sbjct: 773 NMDIRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRAEVDKVGKFGLGFN 832
Query: 1488 CVYHFTDIPMFVSGENIVMFDPHASNLPG--ISPSHPGLRIKFA-GRKILEQFPDQFSSL 1544
VYH TDIP+ +S E ++MFDP+ +++ S+PG++I ++ +K L +FP+QF
Sbjct: 833 SVYHITDIPVIMSREFMIMFDPNINHISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPF 892
Query: 1545 LH-FGCDL------QHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVS 1597
++ F C L + + GTLFR RT A S++ Y D+ SL FS
Sbjct: 893 MNVFDCQLPLTVEAPYSYSGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGH 952
Query: 1598 ETLLFLRNVKSI 1609
++F +NV S+
Sbjct: 953 RLIIFTQNVTSM 964
Score = 155 bits (393), Expect = 1e-35
Identities = 93/303 (30%), Positives = 164/303 (53%), Gaps = 20/303 (6%)
Query: 5 SPESIFLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAG 64
+PE++ E GQ LT RI+ +L YP + + KEL+QNADDA AT S +D R +
Sbjct: 716 NPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMD 775
Query: 65 --DSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVY 122
++LL ++ GPAL ++N++ F++ DF++I+++G S K + K G+FG+GFNSVY
Sbjct: 776 IRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRAEVDKVGKFGLGFNSVY 835
Query: 123 HLTDLPSFVSGKYVVLFDPQGVYLPR--VSAANPGKRIDFT-GSSALSLYKDQFSPY--- 176
H+TD+P +S +++++FDP ++ + +NPG +I+++ L + +QF P+
Sbjct: 836 HITDIPVIMSREFMIMFDPNINHISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPFMNV 895
Query: 177 --CAFGCDMQSP--FAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTL 232
C +++P ++GTLFR R +A S++S Y DI S+ + G +
Sbjct: 896 FDCQLPLTVEAPYSYSGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLI 955
Query: 233 LFLKSVLCIEMYVWDAGEPKPK--------KIHSCSVSSVSDDTIWHRQALLRLSKSLNT 284
+F ++V + + E P K CS +++ I + +L K+ T
Sbjct: 956 IFTQNVTSMYLKYLKIEETNPSLAQDTIVIKKKPCSTKALTAPVISVLKEAAKLMKTCGT 1015
Query: 285 TTE 287
+ +
Sbjct: 1016 SNK 1018
Score = 75.1 bits (183), Expect = 3e-11
Identities = 48/178 (26%), Positives = 87/178 (47%), Gaps = 21/178 (11%)
Query: 340 LLPWASIAACISDNSLNNDVLR--TGQAFCFLPLPVRTGLSVQVNGFFEVSSNRRGIWYG 397
L+P ++A +++ +R G+ FC+LPL ++TGL V +NG F V+SNR+ IW
Sbjct: 1114 LVPCGAVAVLLAEVQDQKWAVRPQAGEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKT 1173
Query: 398 DDMDRSGKVRSIWNRLLLEDLVAPAFVHMLHGVKELLGPTDI----YYSLWPTGSF-EEP 452
D R WN + +V A++ L ++EL ++ Y+++WP +
Sbjct: 1174 DTKGR-------WNTTFMRHVVVKAYLEALSVLRELAASGELTDYTYHTVWPDPDLVHDD 1226
Query: 453 WSILVQQIYINICNA-----PVIYSNLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQL 505
+S++ Q Y +I + ++S+ G WVS D+ K +D+ A ++
Sbjct: 1227 FSVICQGFYEDIAHGKGKDLTRVFSD--GSMWVSMKNVRFLDDSILKRRDVGPAAFKI 1282
Score = 67.4 bits (163), Expect = 6e-09
Identities = 68/257 (26%), Positives = 107/257 (41%), Gaps = 53/257 (20%)
Query: 1696 WIMTECLGGGNVLKGTSEASTSNSHNFVPWACVAAYLNSVKHGEDLVDSAEVEDDCLVSS 1755
W++ C+ G L+ S + + VP VA L AEV+D
Sbjct: 1089 WLICTCMDTGEALR-FSLSESGRRLGLVPCGAVAVLL------------AEVQDQ----- 1130
Query: 1756 DLFQFASLPMHPRENFEGRAFCFLPLPISTGLPAHVNAYFELSSNRRDIWFGSDMTGGGR 1815
++A P G FC+LPL I TGLP H+N F ++SNR++IW +D G
Sbjct: 1131 ---KWAVRPQ------AGEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIW-KTDTKG--- 1177
Query: 1816 KRSDWNIYLLENVVAPAYGRLLEKVALEIGPC-----YLFFSLWP-KTLGLEPWASVIRK 1869
WN + +VV AY L V E+ Y + ++WP L + ++ + +
Sbjct: 1178 ---RWNTTFMRHVVVKAYLEAL-SVLRELAASGELTDYTYHTVWPDPDLVHDDFSVICQG 1233
Query: 1870 LYQFVAEFNLRVL-YTEARGGQWISTKHAIFPDFSFPKADEL-----------IKALSGA 1917
Y+ +A + L + G W+S K+ F D S K ++ +K
Sbjct: 1234 FYEDIAHGKGKDLTRVFSDGSMWVSMKNVRFLDDSILKRRDVGPAAFKIFLKYLKKTGSK 1293
Query: 1918 SLPVITLPQSLLERFME 1934
+L + LP S+ F E
Sbjct: 1294 NLCAVELPSSVKLGFEE 1310
Score = 50.8 bits (120), Expect = 5e-04
Identities = 36/147 (24%), Positives = 78/147 (52%), Gaps = 16/147 (10%)
Query: 2050 TNISFLSCQLLEKLLVKLLPVEWQHASL-VSWTPGIHGQ--PSLEWLQLLWNYLKAN-CD 2105
T + L+ +L+ +++ W L V W P + PS+ WL+++W +L + +
Sbjct: 4 TQLQLLNTDRFARLIKEVMNTFWPGRELIVQWYPCDEDRKHPSVSWLRMVWKHLYVHFSE 63
Query: 2106 DLLMFSKWPILP-----VGDDC--LIQLK-PNLNVIKNDGWS---EKMSSLLVKVGCLFL 2154
DL +F + P++P G C LI+L+ P+L ++ ++ + E ++ ++ K+G + L
Sbjct: 64 DLTLFDEMPLIPRTPLEEGQTCVELIRLRAPSLVILDDESEAQLPEFLADVVQKLGGIVL 123
Query: 2155 RP-DLQLDHPKLECFVQSPTARGVLNV 2180
+ D + HP ++ ++ P+ VL++
Sbjct: 124 KKLDASIQHPLIKKYIHLPSPSAVLHI 150
>ref|XP_595962.1| PREDICTED: similar to spastic ataxia of Charlevoix-Saguenay (sacsin),
partial [Bos taurus]
Length = 794
Score = 229 bits (584), Expect = 9e-58
Identities = 200/673 (29%), Positives = 298/673 (43%), Gaps = 94/673 (13%)
Query: 1374 GLSGAAEAFGQHEA-LTTRLKHILEMYADGPGTLFELVQNAEDAGASEVIFLLDKSQYGT 1432
GL G FGQ L LK IL Y +G L EL+QNAEDAGA+EV FL D++QYGT
Sbjct: 116 GLKGGGR-FGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGT 174
Query: 1433 SSVLSPEMADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHF 1492
++ S +MA +QGPALY +N++VFTP+D + I I + K + +GRFG+GFN VYH
Sbjct: 175 QTLWSKDMAQYQGPALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHI 234
Query: 1493 TDIPMFVSGENIVMFDPHASNLPGISPSHPGLRIKFAGRKILEQFPDQFSSLLH-FGCD- 1550
TD+P SG+ I M DPH + P G K + + QF+ + FG
Sbjct: 235 TDVPCIFSGDQIGMLDPHQTL---FGPRESGQ----DDSKEISELSYQFAPFIGLFGSTK 287
Query: 1551 ---LQHPFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVK 1607
++ FPGT FRFPLR SQ+ +Y + V LF +F LLFL+NV+
Sbjct: 288 ETFVKGSFPGTFFRFPLR----RQPSQLSGTLYNKQKVLELFESFQADADTVLLFLKNVQ 343
Query: 1608 SISIFLKEGTGHEMRLLHRVSR---ASLGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLK 1664
+S+ ++E G E +L+ RV+ A+ G+ E +G + + +
Sbjct: 344 DVSLHVREADGSE-KLVFRVTAREPAAPAPERPGAVEA------------LGAALSDYCE 390
Query: 1665 KLSLSIDRDLPYKCQKILITEQGTHGRNSHYWIMTECLGGGNVLKGTSEASTSNSHNFVP 1724
++ + Y I++ + G W++ +GG + + ++ FVP
Sbjct: 391 RVPSGGVTCVTYPV-SIVLEDGDAQGARETSWLVCNSVGGRGL--SAQLDALADELRFVP 447
Query: 1725 WACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMHPRENFEGRAFCFLPLP-- 1782
+A L+ + H F G+AFCFLPLP
Sbjct: 448 VIGIATPLSGLAE---------------------------EHGAAGFSGKAFCFLPLPPG 480
Query: 1783 --ISTGLPAHVNAYFELSSNRRDI-WFGSDMTGGGRKRSDWNIYLLENVVAPAYGRL-LE 1838
TGLP HV+ +F L+ NRR I W ++ + WN L+ +VV AY L L+
Sbjct: 481 EESRTGLPVHVSGFFGLTDNRRSIKW--RELDQWRDPAAVWNELLVLSVVPRAYAALILD 538
Query: 1839 KVALEIGPCYL--------FFSLWPKTLGLE-PWASVIRKLYQFVAEFNLRVLYTEARGG 1889
VA C + LWP ++ PW + L+Q + F VL + GG
Sbjct: 539 AVARLRAGCSPGLPLSVAGVYGLWPDAAQVKLPWRPALEPLFQEL--FQHEVL--PSLGG 594
Query: 1890 QWISTKHAIFPDF--SFPKADELIKALSGASLPVITLPQSLLERFMEICPS---LHFLKP 1944
W+ + A F D A +++ L + V+ +P L + S L + P
Sbjct: 595 HWVPLEQACFSDLDEGLDYAPAVLRFLQRSGKEVVRVPAHLAAAAQLMASSAGPLTQVTP 654
Query: 1945 KLLRTLLIRRKREFKDRDAMILTLEYCLHDFEESMQFDTLGGLPLLPLADGSFTSIEMKG 2004
R +L + + LE+ L D + L GL LLPL G+F
Sbjct: 655 AWTRQVLRKVGLGGASAPERLHLLEFVLSD----QAYSELLGLELLPLQSGAFLPFSSSA 710
Query: 2005 IGERVYIARGDEY 2017
+ V +E+
Sbjct: 711 CDQDVIYIASEEH 723
Score = 224 bits (572), Expect = 2e-56
Identities = 202/655 (30%), Positives = 309/655 (46%), Gaps = 57/655 (8%)
Query: 14 FGQTVD-LTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSSSL 72
FGQT L ++++L YPEG +LKELIQNA+DAGAT V D + +L S +
Sbjct: 123 FGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTQTLWSKDM 182
Query: 73 SQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLPSFVS 132
+Q+QGPAL YN+AVFT +D+ I +I S K K GRFG+GFNSVYH+TD+P S
Sbjct: 183 AQYQGPALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFS 242
Query: 133 GKYVVLFDP-QGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCA-FGCD----MQSP 186
G + + DP Q ++ PR S + K I S LS QF+P+ FG ++
Sbjct: 243 GDQIGMLDPHQTLFGPRESGQDDSKEI-----SELSY---QFAPFIGLFGSTKETFVKGS 294
Query: 187 FAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVW 246
F GT FRFPLR S+LS Y + + +F + LLFLK+V + ++V
Sbjct: 295 FPGTFFRFPLRR----QPSQLSGTLYNKQKVLELFESFQADADTVLLFLKNVQDVSLHVR 350
Query: 247 DAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTE-VDAFPLEFVTEAVRGVET 305
+A + K + + + A+ L +L+ E V + + VT V V
Sbjct: 351 EA-DGSEKLVFRVTAREPAAPAPERPGAVEALGAALSDYCERVPSGGVTCVTYPVSIV-- 407
Query: 306 VRQVDRFYIVQTMASASSRIGSFAITASKEY---DIQLLPWASIAACISDNSLNNDVLR- 361
+ D +T + +G ++A + +++ +P IA +S + +
Sbjct: 408 LEDGDAQGARETSWLVCNSVGGRGLSAQLDALADELRFVPVIGIATPLSGLAEEHGAAGF 467
Query: 362 TGQAFCFLPLP----VRTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLED 417
+G+AFCFLPLP RTGL V V+GFF ++ NRR I + ++D+ ++WN LL+
Sbjct: 468 SGKAFCFLPLPPGEESRTGLPVHVSGFFGLTDNRRSIKW-RELDQWRDPAAVWNELLVLS 526
Query: 418 LVAPAFVHM-LHGVKELLG------PTDI--YYSLWP-TGSFEEPWSILVQQIYINICNA 467
+V A+ + L V L P + Y LWP + PW ++ ++ +
Sbjct: 527 VVPRAYAALILDAVARLRAGCSPGLPLSVAGVYGLWPDAAQVKLPWRPALEPLFQELFQH 586
Query: 468 PVIYSNLGGGRWVSPSEAFLH--DEKFTKSKDLSLALMQLGMPVVHLPNSLFDMLLKYNS 525
V+ S GG WV +A DE + + L + G VV +P L S
Sbjct: 587 EVLPSL--GGHWVPLEQACFSDLDEGLDYAPAVLRFLQRSGKEVVRVPAHLAAAAQLMAS 644
Query: 526 S----KVITPGTVRQFLRECESCNHLSRAHKLLLLEYCLEDLVDDDVGKAAYNLPLLPLA 581
S +TP RQ LR+ S +L LLE+ L D ++ L LLPL
Sbjct: 645 SAGPLTQVTPAWTRQVLRKV-GLGGASAPERLHLLEFVLSDQAYSEL----LGLELLPLQ 699
Query: 582 NGNFASFLEAS--KGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMS 634
+G F F ++ + + Y +E L + R + ++ P++L L A +
Sbjct: 700 SGAFLPFSSSACDQDVIYIASEEHPRSLFPGLEGRFLLDNLKPHLLAALKEAAQT 754
>ref|XP_647015.1| hypothetical protein DDB0190083 [Dictyostelium discoideum]
gi|60475078|gb|EAL73014.1| hypothetical protein
DDB0190083 [Dictyostelium discoideum]
Length = 2661
Score = 139 bits (351), Expect = 9e-31
Identities = 239/1067 (22%), Positives = 427/1067 (39%), Gaps = 158/1067 (14%)
Query: 16 QTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSS----- 70
QT+ +R+ LLNYPE + + +ELIQNA+DA A TV + +D S+ + LL S
Sbjct: 7 QTIKPAHFLRDNLLNYPE-SKIFRELIQNAEDARADTVIIKVDEGSYPNNGLLISNDNQE 65
Query: 71 --SLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLP 128
S + GP++L YN+A F + D+ I +I SK G FG+G+NSVYH+TD P
Sbjct: 66 IQSSKELLGPSILIYNNATFQKHDWEGICQISQGSKKENLKSVGNFGLGWNSVYHITDNP 125
Query: 129 SFVSGKYVVLFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFA 188
SG V DP R+S D + + + F + C+ + F
Sbjct: 126 IVYSGNNVWFADPN----ERMSGGLFFDLDDEDDYNKCLSFLEPFIQFKESNCNPKEYFN 181
Query: 189 GTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDA 248
GT+ R PLR S++ + T + I + + ++ L+FLKS+ I + V
Sbjct: 182 GTIIRLPLR----IYPSEIKKAVLTMDAIKKILNEFSKDINEILIFLKSLASITIIV--- 234
Query: 249 GEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSL-----NTTTEVDAFPLEFVTEAVRGV 303
+ I+S S+S+ S + L L+ + N ++ V+ + ++
Sbjct: 235 ---NNQIINSVSISNYSKIKEKREKVSLFLANIVDNEMNNPSSAVELAEILCSNKSQSNC 291
Query: 304 ETVRQVDRFYIVQTMASASSRIGSFAIT------------ASKEYDIQLLPWASIAACIS 351
E+ Q+D ++ + +S++ S+ ++ K +I+L+ + +A I
Sbjct: 292 ESTFQID----LEIYRNGASQLISYLVSQGIYIDRKLIELVKKNKEIKLISYGGVAVPI- 346
Query: 352 DNSLNNDVLRTGQAFCFLPLPVRT-GLSVQVNGFFEVSSNRRGIWYG--DDMDRSGKVRS 408
SL+ + G+ F FLP+ + + VNG+F +S+ R I Y + + S +
Sbjct: 347 --SLDGPINFKGKPFTFLPIGALVYDIPLHVNGYFRLSNARDNIIYSLTEVEEASESLSK 404
Query: 409 IWNRLLLEDLVAPAFVHMLHGVKELLGPTDIYYSLWPTGSFEEPWSILVQQIYINICNAP 468
WN + E ++ +V L +K G Y+ +P + + I+I
Sbjct: 405 QWNMFISETIIPYFYVKSLEYLKLNYGGE--LYNYFPYKCNNQNYQGQSPSYDISITTMK 462
Query: 469 VIYSNLGGGRWVSPSEAF-LHDEKFTKSKDLS-----LALMQLGMPVVHLPNSLFDMLLK 522
I + +PSE L+ S D+ L + + + L N ++L
Sbjct: 463 SIIGGKYFLNYFNPSEYLPLNGSLIISSSDMPPDFILTILKERNIKTIKLSN---ELLNH 519
Query: 523 YNSSKVITPGTVRQFLRECESCNHLSRAHKLLLLEYCLEDLVDDDVGKAAYNLPLLPLAN 582
+N+ ++ +Q+L + L + + ++ C ++V LP P N
Sbjct: 520 FNNLRIPLTCYSKQYLCSLLVSSPLKQYSEDVINYICCTEIVQGGHLNKVKILPTNP--N 577
Query: 583 GNFASFLEASKGIPYFICDELEYKLLEPVSDRVID----------------QSIPPNILT 626
N L+ S+ + IC+ L +SD+V D ++PPN
Sbjct: 578 KNTLDCLKLSQTLS-DICNNTNQFLC--MSDQVYDLLFGYHGQSLTYHLKLSTMPPNFRK 634
Query: 627 RLSGIAMSSNTNIALFSIHHFAHLFPVFMPDDWKYKCKVFWDPDSCQKPTSSWFVLFWQY 686
+S + +NI + +F W +C K
Sbjct: 635 FIS-LICEKYSNIKEIKLSNFLTSLKSLSSQFLNENIITVW---NCIKEL---------- 680
Query: 687 LGKQSEILPLFK--DWPILP-----STSGHLLRPSRQLKMINGSTLSDTVQDILVKIGCH 739
+++E L L K PI+P + +G L M L ++ IL K+
Sbjct: 681 --EKNETLQLSKIRSIPIVPFRSSTTQTGVTSYDKSSLLMYRSKFL--PIEPILNKLNI- 735
Query: 740 ILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAEERNELRRFLLD 799
Y+VE F+ L GN + +Q + SL ++E ++LR FL++
Sbjct: 736 -----YLVEEEHQFNSLLSGND--------QISKMLDYLQKVYLSLDSDEIDKLRIFLVE 782
Query: 800 PQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENPRKYLPPLDVPEFILVGIE 859
S+ + +I LPI+ + D +FS + + + ++ + G++
Sbjct: 783 LIHQA--SLSKADISIFYNLPIHPCI---GSSDQKFSSITYKSICVDYEKIDQYEIKGLK 837
Query: 860 FIVRSSNTEEDILSRYYGVER--------MGKAQFYKKHVFDRVGELQAEDRDSIMLSVL 911
I + + LS+Y + G+ Q Y+ ++ +G + I+ L
Sbjct: 838 LI------KVNELSKYKSIVDSIPTKQIFKGEKQIYRFYLIPNIGSFELNVSIEIITKFL 891
Query: 912 QNLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLY--DPRNEEIYALLEDSDSFPSGV 969
++D LR LKFIP+ G P Y P ++ E PS +
Sbjct: 892 TLYGNHYVDDGE----LRKLKFIPSENGVYSTPDSFYVLGPLERDLIRNFE-----PSKI 942
Query: 970 FRESETLDIMRG----LGLKTSVSPDTVLESARCIEHLMHEDQQKAY 1012
+S LD + G GLK +S + ++ I+ L ++D + Y
Sbjct: 943 LNQS--LDGLTGYLSKFGLKFKLSDKHI--CSKVIDFLSNQDSIETY 985
Score = 114 bits (286), Expect = 3e-23
Identities = 111/485 (22%), Positives = 209/485 (42%), Gaps = 68/485 (14%)
Query: 10 FLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRS-------- 61
F FGQ DL R++++L +Y + L E++QNA DAG+T V L LD S
Sbjct: 1285 FDHSFGQKEDLVDRLKQILNDY-KVEVFLNEMVQNAHDAGSTEVKLILDCNSLKQQFLKE 1343
Query: 62 HAGDSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSV 121
+ S L L + +LL YN++VFT+DD ++ + S K G+ G+G NS+
Sbjct: 1344 NPEISTLCKDLPSYFESSLLFYNNSVFTDDDIKNVQAMTASIKKQDEKCIGQHGLGINSM 1403
Query: 122 YHLTDLPSFVSGKYVVLFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPY----C 177
Y +D P +SG+Y+++FDP ++ + + G + S Y F P+
Sbjct: 1404 YSFSDCPCILSGEYLMIFDPFVTHIGQSINYSHGAKYKI---SQYKPYLKYFKPFQHLQS 1460
Query: 178 AFGCDM-QSPFAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLK 236
F D+ F GT+ R PLR +S Q + ++ ++ + L+F
Sbjct: 1461 IFDFDLDDGKFNGTIIRLPLRKIQNDGNRHISPQKWNEANVLDYLKRVKASNLENLMFFT 1520
Query: 237 SVLCIEMYVWDAGEPKPKK---IHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPL 293
++ +E+ + G K ++ IH S S+ + + + +N T+V +
Sbjct: 1521 NIDSLEVSILPVGSKKLEQQISIHKKSSLSLITN---------QYNNLMNIPTQVSEYTF 1571
Query: 294 EFVTEAVRGVETVRQVDRFYIVQTMASASSRIGSFAITASKEY-----DIQLLPWASIAA 348
+ E + +++ I Q + + + + ++ + + P +A
Sbjct: 1572 TIIPS-----EKSKITEKYIIGQVIEEDFKDLSEYPDNKALKFLSIYNNEKRKPVGGVAF 1626
Query: 349 CISDNSLNNDVLRTGQAFCFLPL-PVRTGLSVQVNGFFEVSSNR-------RGIWYGDDM 400
+ D SL + T ++FC+LP + + + V ++ F +S+R Y +
Sbjct: 1627 KLPDFSL-PEYKFTPKSFCYLPYKDLISNIPVHIHANFSTTSSRDILENAKSSNLYNIEE 1685
Query: 401 DRSGKVRSI----------WNRLLLEDLVAPAFVHML----------HGVKELLGPTDIY 440
S KV + WN+L++ +++AP +++ L + + + D Y
Sbjct: 1686 ILSKKVDQVIQQSDSFQLFWNQLIVTEIIAPLYINTLTLFKNKYIKGNDIDIISKYHDFY 1745
Query: 441 YSLWP 445
YS +P
Sbjct: 1746 YSRFP 1750
Score = 107 bits (266), Expect = 6e-21
Identities = 73/213 (34%), Positives = 112/213 (52%), Gaps = 15/213 (7%)
Query: 1408 ELVQNAEDAGASEVIFLLDKSQYGTSSVL-SPEMADWQ------GPALYCFNDSVFTPQD 1460
EL+QNAEDA A VI +D+ Y + +L S + + Q GP++ +N++ F D
Sbjct: 30 ELIQNAEDARADTVIIKVDEGSYPNNGLLISNDNQEIQSSKELLGPSILIYNNATFQKHD 89
Query: 1461 LYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIVMFDPHASNLPGISPS 1520
I +I Q SK E ++G FGLG+N VYH TD P+ SG N+ DP+ G+
Sbjct: 90 WEGICQISQGSKKENLKSVGNFGLGWNSVYHITDNPIVYSGNNVWFADPNERMSGGL--- 146
Query: 1521 HPGLRIKFAGRKILEQFPDQFSSLLHFGCDLQHPFPGTLFRFPLRTAGVASRSQIKKEVY 1580
L + K L F + F C+ + F GT+ R PLR S+IKK V
Sbjct: 147 FFDLDDEDDYNKCL-SFLEPFIQFKESNCNPKEYFNGTIIRLPLR----IYPSEIKKAVL 201
Query: 1581 TPEDVRSLFAAFSEVVSETLLFLRNVKSISIFL 1613
T + ++ + FS+ ++E L+FL+++ SI+I +
Sbjct: 202 TMDAIKKILNEFSKDINEILIFLKSLASITIIV 234
Score = 105 bits (261), Expect = 2e-20
Identities = 85/281 (30%), Positives = 132/281 (46%), Gaps = 22/281 (7%)
Query: 1342 VHGNISNDVAEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYAD 1401
+H IS + A KL + L +++ ++ A +FGQ E L RLK IL Y
Sbjct: 1258 LHNKISENTASKLNIIKLSQLIQSQVAFD---------HSFGQKEDLVDRLKQILNDYKV 1308
Query: 1402 GPGTLFELVQNAEDAGASEVIFLLD----KSQYGTS----SVLSPEMADWQGPALYCFND 1453
L E+VQNA DAG++EV +LD K Q+ S L ++ + +L +N+
Sbjct: 1309 EV-FLNEMVQNAHDAGSTEVKLILDCNSLKQQFLKENPEISTLCKDLPSYFESSLLFYNN 1367
Query: 1454 SVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIVMFDPHASN 1513
SVFT D+ + + K + IG+ GLG N +Y F+D P +SGE +++FDP ++
Sbjct: 1368 SVFTDDDIKNVQAMTASIKKQDEKCIGQHGLGINSMYSFSDCPCILSGEYLMIFDPFVTH 1427
Query: 1514 L-PGISPSHPGLRIKFAGRKILEQFPDQFSSLLH-FGCDLQH-PFPGTLFRFPLRTAGVA 1570
+ I+ SH G + K + K ++ F L F DL F GT+ R PLR
Sbjct: 1428 IGQSINYSH-GAKYKISQYKPYLKYFKPFQHLQSIFDFDLDDGKFNGTIIRLPLRKIQND 1486
Query: 1571 SRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISI 1611
I + + +V E L+F N+ S+ +
Sbjct: 1487 GNRHISPQKWNEANVLDYLKRVKASNLENLMFFTNIDSLEV 1527
Score = 45.8 bits (107), Expect = 0.018
Identities = 26/79 (32%), Positives = 44/79 (54%), Gaps = 3/79 (3%)
Query: 1770 NFEGRAFCFLPL-PISTGLPAHVNAYFELSSNRRDIWFG-SDMTGGGRKRS-DWNIYLLE 1826
NF+G+ F FLP+ + +P HVN YF LS+ R +I + +++ S WN+++ E
Sbjct: 353 NFKGKPFTFLPIGALVYDIPLHVNGYFRLSNARDNIIYSLTEVEEASESLSKQWNMFISE 412
Query: 1827 NVVAPAYGRLLEKVALEIG 1845
++ Y + LE + L G
Sbjct: 413 TIIPYFYVKSLEYLKLNYG 431
>ref|XP_647016.1| hypothetical protein DDB0190084 [Dictyostelium discoideum]
gi|60475079|gb|EAL73015.1| hypothetical protein
DDB0190084 [Dictyostelium discoideum]
Length = 2673
Score = 131 bits (329), Expect = 3e-28
Identities = 217/1009 (21%), Positives = 407/1009 (39%), Gaps = 149/1009 (14%)
Query: 16 QTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSS----- 70
Q + ++ +R LLNYPE + +++ELIQNA+DA A T + +D S+ + LL S
Sbjct: 7 QRLKVSHSLRNNLLNYPE-SKIVRELIQNAEDALADTFIIKVDEGSYPNNGLLISNDNQE 65
Query: 71 --SLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLP 128
S + GP++L YN+A F E D+ I +I SK G FG+G+NSVYH+TD P
Sbjct: 66 IESSKELLGPSILIYNNATFHEQDWEGICEINQGSKKENLKSVGNFGLGWNSVYHITDNP 125
Query: 129 SFVSGKYVVLFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFA 188
SG V DP R+ D + + + F + C+ + F
Sbjct: 126 IVYSGNNVWFADPN----ERIGGGLFFDLDDEDDYNKCFSFLEPFIQFKESNCNPKEYFN 181
Query: 189 GTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDA 248
GT+ R PLR S++ + T + I + + ++ L+FLKS+ I + V
Sbjct: 182 GTIIRLPLR----IYPSEIKKAVLTMDAIKKILNEFSKDINEILIFLKSLASITIIV--- 234
Query: 249 GEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSL-----NTTTEVDAFPLEFVTEAVRGV 303
+ ++S + + S + L LSK + N ++ V+ + ++
Sbjct: 235 ---NNQIVNSVKIKNYSKIKDQREKVSLFLSKIVDNEMNNPSSAVELAEILCSNKSQSNC 291
Query: 304 ETVRQVDRFYIVQTMASASSRIGSFAIT------------ASKEYDIQLLPWASIAACIS 351
E+ Q+D ++ + S++ S+ ++ K +I+L+ + +A I
Sbjct: 292 ESTFQID----LEIYRNGVSQLISYLVSQGIYIDRKLIELVKKNKEIKLISYGGVAVPI- 346
Query: 352 DNSLNNDVLRTGQAFCFLPLPVRT-GLSVQVNGFFEVSSNRRGIWYG--DDMDRSGKVRS 408
SL++ + G+ F FLP+ + + VNG+F +S+ R I Y + + S +
Sbjct: 347 --SLDSSINFKGKPFTFLPIGALVYDIPLHVNGYFRLSNARDNIIYSLTEVEEASESLSK 404
Query: 409 IWNRLLLEDLVAPAFVHMLHGVKELLGPTDIYYSLWPTGSFEEPW--------------- 453
WN+ + E ++ +V L +K Y+ +P E +
Sbjct: 405 QWNKFISETIIPYFYVKSLEYLKS--NYLVKLYNYFPYKCNNENYQGQSPAYDISITTMK 462
Query: 454 SILVQQIYINICNAPVIYSNLGGGRWVSPSEAFLHDEKFTKSKDLSLALMQLGMPVVHLP 513
SI+ + ++N N+ Y L G +S S+ D T ++ ++ + L +++
Sbjct: 463 SIIGGKYFLNYFNSHE-YLPLIGSLIISSSD-IPPDFVLTIIRERNIKTIFLSNELLNHF 520
Query: 514 NSLFDMLLKYNSS---KVITPGTVRQFLRECES---CNHLSRAHKLLLLEY--CLEDLVD 565
N+L LL Y+ ++ ++Q+ + + C + L ++ + +
Sbjct: 521 NNLRISLLCYSKQYLCSLLVSSPLKQYSEDVINYICCTEIIEGGHLNMVNILPTNSNNIT 580
Query: 566 DDVGKAAYNLPLLPLAN--GNFASFLEASKGIPYFICDELEYKLLEPVSDRVIDQSIPPN 623
D K+ LP P N NF S + G Y ++ Y +SD+V D
Sbjct: 581 LDCLKSTQTLPYFPCQNYHSNFGSHINFGMGHSYININQFLY-----MSDQVYD------ 629
Query: 624 ILTRLSGIAMSSNTNIALFSIHHFAHLFPVFMPDDWKYKCKVFWDPDSCQ--------KP 675
+L R G +++ + I+ + + + C+ +W+ + K
Sbjct: 630 LLFRYHGQSLTFHLKISTMPPNFRKFISAI---------CRKYWNIGEIKLSNFLTSLKS 680
Query: 676 TSSWF-----VLFWQYLGKQ--SEILPLFK--DWPILPSTSGHLLR-----PSRQLKMIN 721
S+ F + W + + +E L L K PI+P S L M
Sbjct: 681 LSNKFLKEHIITVWGCIDELGINETLELSKIRSIPIVPYRSSPTQTDVTSYDKSSLLMYR 740
Query: 722 GSTLSDTVQDILVKIGCHILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVS 781
L ++ IL K+ Y++E F+ L +A + + N + +
Sbjct: 741 SKLL--PIEPILNKLNI------YIIEEEHQFNNLL--HATAYISKLLNYLKNVD----- 785
Query: 782 FSSLIAEERNELRRFLLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREPTQDSQFSDLENP 841
SL ++E ++LR FL++ H +I LPI+ D +FS + N
Sbjct: 786 -LSLDSDEIDKLRIFLVESI----HQASIADISIFYNLPIHPCI---GNSDQKFSSITNN 837
Query: 842 RKYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVER--MGKAQFYKKHVFDRVGELQ 899
+ + ++ + G++ I + ++ + Y ++ +G+ Q Y+ ++ + +
Sbjct: 838 SICVDYEKIDQYEIKGLKLIKVNELSKYKRIVDYIPTKQILIGEKQVYRYYLIQNISSFE 897
Query: 900 AEDRDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLY 948
I+ L + D + LR KFIP+ P Y
Sbjct: 898 LNVSIEIITEFLTLYGNHYINDGA----LRKFKFIPSENDVYSTPDSFY 942
Score = 106 bits (265), Expect = 8e-21
Identities = 106/486 (21%), Positives = 210/486 (42%), Gaps = 72/486 (14%)
Query: 10 FLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRS-------- 61
F FGQ +L R++++L +Y + L E++QNA DAG+T V L LD S
Sbjct: 1304 FENSFGQKEELVDRLKQILRDY-KVEVFLNEMVQNAHDAGSTEVKLILDCNSLKQQFLKE 1362
Query: 62 HAGDSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSV 121
+ S L L + +LL YN++VFTE D ++ + S K + G+ G+G NS+
Sbjct: 1363 NPEISTLCKDLPSYFESSLLFYNNSVFTEKDIKNVQVMSASIKKQDENSIGQHGLGINSM 1422
Query: 122 YHLTDLPSFVSGKYVVLFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPY----C 177
Y +D P +SG+Y+++FDP ++ + + G + + Y F P+
Sbjct: 1423 YSFSDCPCILSGEYLMIFDPFVTHIGQSINYSHGAKYKISEYKTFLKY---FKPFQHLQS 1479
Query: 178 AFGCDMQS-PFAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLK 236
G D+ F GT+ R PLR R +S Q + ++ ++ + L+F
Sbjct: 1480 ILGFDLDDGKFNGTIIRLPLRKTLNDDRF-ISPQKWNEVNVLDYLKRVKASNLENLMFFT 1538
Query: 237 SVLCIEMYVWDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRL-----SKSLNTTTEVDAF 291
++ +E+ + G K ++ S H+++ L L + +N T+ +
Sbjct: 1539 NIDSLEVSILPVGSKKLEQQISI-----------HKESSLSLITNQYNNLMNIPTQASEY 1587
Query: 292 PLEFVTEAVRGVETVRQVDRFYIVQTMASASSRIGSFAITASKEY-----DIQLLPWASI 346
+ E + +++ I Q + + + + ++ + + P +
Sbjct: 1588 TFTIIPS-----EKSKITEKYIIGQVIEEDFKDLSEYPDNKALKFLSIYNNEKRKPVGGV 1642
Query: 347 AACISDNSLNNDVLRTGQAFCFLPLP-VRTGLSVQVNGFFEVSSNRRGIWY--------- 396
A + D SL + T ++FCFLP + + + V ++ F +S+R +
Sbjct: 1643 AFKLIDFSLP-EYNFTPKSFCFLPYKDLISNIPVHIHANFSTTSSRDILENVKSSNLYNI 1701
Query: 397 -------GDDMDRSGKVRSIWNRLLLEDLVAPAFVHML----------HGVKELLGPTDI 439
+ + ++ ++ WN+L++ +++AP +++ L + + + D
Sbjct: 1702 EEILSKKDNQVIQTDSLQLCWNQLIVTEIIAPLYINTLTLFKNKYIKGNDIDIISKYHDF 1761
Query: 440 YYSLWP 445
YYS +P
Sbjct: 1762 YYSRFP 1767
Score = 105 bits (261), Expect = 2e-20
Identities = 86/282 (30%), Positives = 136/282 (47%), Gaps = 25/282 (8%)
Query: 1342 VHGNISNDVAEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYAD 1401
+H IS + A KL + L +++ ++ A +FGQ E L RLK IL Y
Sbjct: 1277 LHNKISENTASKLSITKLSQLIQSQVAFE---------NSFGQKEELVDRLKQILRDYKV 1327
Query: 1402 GPGTLFELVQNAEDAGASEVIFLLD----KSQYGTS----SVLSPEMADWQGPALYCFND 1453
L E+VQNA DAG++EV +LD K Q+ S L ++ + +L +N+
Sbjct: 1328 EV-FLNEMVQNAHDAGSTEVKLILDCNSLKQQFLKENPEISTLCKDLPSYFESSLLFYNN 1386
Query: 1454 SVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIVMFDPHASN 1513
SVFT +D+ + + K + +IG+ GLG N +Y F+D P +SGE +++FDP ++
Sbjct: 1387 SVFTEKDIKNVQVMSASIKKQDENSIGQHGLGINSMYSFSDCPCILSGEYLMIFDPFVTH 1446
Query: 1514 L-PGISPSHPGLRIKFAGRKILEQFPDQF---SSLLHFGCDLQHPFPGTLFRFPLRTAGV 1569
+ I+ SH G + K + K ++ F S+L F D F GT+ R PLR
Sbjct: 1447 IGQSINYSH-GAKYKISEYKTFLKYFKPFQHLQSILGFDLD-DGKFNGTIIRLPLRKTLN 1504
Query: 1570 ASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISI 1611
R I + + +V E L+F N+ S+ +
Sbjct: 1505 DDRF-ISPQKWNEVNVLDYLKRVKASNLENLMFFTNIDSLEV 1545
Score = 103 bits (257), Expect = 7e-20
Identities = 79/283 (27%), Positives = 136/283 (47%), Gaps = 27/283 (9%)
Query: 1408 ELVQNAEDAGASEVIFLLDKSQYGTSSVLSPE-------MADWQGPALYCFNDSVFTPQD 1460
EL+QNAEDA A I +D+ Y + +L + GP++ +N++ F QD
Sbjct: 30 ELIQNAEDALADTFIIKVDEGSYPNNGLLISNDNQEIESSKELLGPSILIYNNATFHEQD 89
Query: 1461 LYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIVMFDPHASNLPGISPS 1520
I I Q SK E ++G FGLG+N VYH TD P+ SG N+ DP+ + G
Sbjct: 90 WEGICEINQGSKKENLKSVGNFGLGWNSVYHITDNPIVYSGNNVWFADPN-ERIGG---- 144
Query: 1521 HPGLRIKFAGRKILEQ---FPDQFSSLLHFGCDLQHPFPGTLFRFPLRTAGVASRSQIKK 1577
GL + F + F C+ + F GT+ R PLR S+IKK
Sbjct: 145 --GLFFDLDDEDDYNKCFSFLEPFIQFKESNCNPKEYFNGTIIRLPLR----IYPSEIKK 198
Query: 1578 EVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLH------RVSRAS 1631
V T + ++ + FS+ ++E L+FL+++ SI+I + + +++ + + + S
Sbjct: 199 AVLTMDAIKKILNEFSKDINEILIFLKSLASITIIVNNQIVNSVKIKNYSKIKDQREKVS 258
Query: 1632 LGESEIGSAEVQDVFNFFKEDRLVGMNRAQFLKKLSLSIDRDL 1674
L S+I E+ + + + ++ N++Q + + ID ++
Sbjct: 259 LFLSKIVDNEMNNPSSAVELAEILCSNKSQSNCESTFQIDLEI 301
Score = 41.6 bits (96), Expect = 0.33
Identities = 24/72 (33%), Positives = 40/72 (55%), Gaps = 3/72 (4%)
Query: 1770 NFEGRAFCFLPL-PISTGLPAHVNAYFELSSNRRDIWFG-SDMTGGGRKRS-DWNIYLLE 1826
NF+G+ F FLP+ + +P HVN YF LS+ R +I + +++ S WN ++ E
Sbjct: 353 NFKGKPFTFLPIGALVYDIPLHVNGYFRLSNARDNIIYSLTEVEEASESLSKQWNKFISE 412
Query: 1827 NVVAPAYGRLLE 1838
++ Y + LE
Sbjct: 413 TIIPYFYVKSLE 424
>ref|XP_647014.1| hypothetical protein DDB0190082 [Dictyostelium discoideum]
gi|60475077|gb|EAL73013.1| hypothetical protein
DDB0190082 [Dictyostelium discoideum]
Length = 2660
Score = 131 bits (329), Expect = 3e-28
Identities = 118/443 (26%), Positives = 206/443 (45%), Gaps = 49/443 (11%)
Query: 16 QTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRSHAGDSLLSS----- 70
QT+ L+ +R+ LLNYPE + + +ELIQNA+DA A TV + +D S+ + LL S
Sbjct: 7 QTIKLSHFLRDNLLNYPE-SKIFRELIQNAEDARADTVIIKVDEGSYPNNGLLISNDNQE 65
Query: 71 --SLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSVYHLTDLP 128
S + GP++L YN+A F E D+ I +I SK G FG+G+NSVYH+TD P
Sbjct: 66 IESSKELLGPSILIYNNATFQEHDWEGICQISQGSKKENLKSVGNFGLGWNSVYHITDNP 125
Query: 129 SFVSGKYVVLFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPYCAFGCDMQSPFA 188
SG V DP R+S D + + F + C+ + F
Sbjct: 126 IVYSGNNVWFSDPN----ERMSGGLFFDLDDEDDYKKCFSFLEPFIQFKESNCNPKEYFN 181
Query: 189 GTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLKSVLCIEMYVWDA 248
GT+ R PLR S++ + T + I + + ++ L+FLKS+ I + V
Sbjct: 182 GTIIRLPLR----IFPSEIKKGVLTMDAIKKILNEFSKDINEILIFLKSLASITIIV--- 234
Query: 249 GEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFV-----TEAVRGV 303
+ ++S ++S+ S + L L+K ++ + + +EF ++
Sbjct: 235 ---NNQIVNSVNISNYSKIKDQREKVSLFLAKIVDNEMKDPSSSVEFAEILCSKKSQSNC 291
Query: 304 ETVRQVDRFYIVQTMASASSRIGSFAIT------------ASKEYDIQLLPWASIAACIS 351
E+ Q+D ++ + S++ S+ ++ K +I+L+ + A I
Sbjct: 292 ESTFQID----LEIYRNGVSQLISYLVSQGIYIDRKLIELVKKNKEIKLISYGGTAIPI- 346
Query: 352 DNSLNNDVLRTGQAFCFLPL-PVRTGLSVQVNGFFEVSSNRRGIWYG--DDMDRSGKVRS 408
+L++ + G+ F FLP+ + + + VNG+F +S+ R I Y + + S +
Sbjct: 347 --NLDSSIKFKGKPFTFLPIGGLVYDIPLHVNGYFRLSNARDNIIYSLTEVEEASESLSK 404
Query: 409 IWNRLLLEDLVAPAFVHMLHGVK 431
WN + E ++ +V L +K
Sbjct: 405 QWNMFISETIIPYFYVKSLQYLK 427
Score = 106 bits (265), Expect = 8e-21
Identities = 76/240 (31%), Positives = 121/240 (49%), Gaps = 18/240 (7%)
Query: 1384 QHEALTTRLKHILE--MYADGPGTLF-ELVQNAEDAGASEVIFLLDKSQYGTSSVLSPE- 1439
Q+++ T +L H L + +F EL+QNAEDA A VI +D+ Y + +L
Sbjct: 3 QNKSQTIKLSHFLRDNLLNYPESKIFRELIQNAEDARADTVIIKVDEGSYPNNGLLISND 62
Query: 1440 ------MADWQGPALYCFNDSVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFT 1493
+ GP++ +N++ F D I +I Q SK E ++G FGLG+N VYH T
Sbjct: 63 NQEIESSKELLGPSILIYNNATFQEHDWEGICQISQGSKKENLKSVGNFGLGWNSVYHIT 122
Query: 1494 DIPMFVSGENIVMFDPHASNLPGISPSHPGLRIKFAGRKILEQFPDQFSSLLHFGCDLQH 1553
D P+ SG N+ DP+ G+ L + +K F + F C+ +
Sbjct: 123 DNPIVYSGNNVWFSDPNERMSGGL---FFDLDDEDDYKKCF-SFLEPFIQFKESNCNPKE 178
Query: 1554 PFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISIFL 1613
F GT+ R PLR S+IKK V T + ++ + FS+ ++E L+FL+++ SI+I +
Sbjct: 179 YFNGTIIRLPLR----IFPSEIKKGVLTMDAIKKILNEFSKDINEILIFLKSLASITIIV 234
Score = 106 bits (264), Expect = 1e-20
Identities = 124/563 (22%), Positives = 235/563 (41%), Gaps = 72/563 (12%)
Query: 10 FLEDFGQTVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATTVSLCLDRRS-------- 61
F FGQ +L R++++L +Y + L E++QNA DAG+T V L LD S
Sbjct: 1287 FDNSFGQKEELVDRLKQILHDY-KVEVFLNEMVQNAHDAGSTEVKLILDCNSLKQQFLKE 1345
Query: 62 HAGDSLLSSSLSQWQGPALLAYNDAVFTEDDFISISKIGGSSKHGQASKTGRFGVGFNSV 121
+ S + LS + +LL YN++VFTE D ++ + S K G+ G+G NS+
Sbjct: 1346 NPEISTVCKDLSSYFESSLLFYNNSVFTEKDIKNVQVMSASIKKQDEKCIGQHGLGINSM 1405
Query: 122 YHLTDLPSFVSGKYVVLFDPQGVYLPRVSAANPGKRIDFTGSSALSLYKDQFSPY----C 177
Y +D P +SG+Y+++FDP ++ + + G + S Y F P+
Sbjct: 1406 YSFSDCPCILSGEYLMIFDPFVTHIGQSINYSHGAKYKI---SQYKTYLKYFKPFQHLQS 1462
Query: 178 AFGCDM-QSPFAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLFEEGVLTLLFLK 236
G D+ F GT+ R PLR R +S Q + ++ ++ + L+F
Sbjct: 1463 ILGFDLDDGKFNGTIIRLPLRKTLNDDRF-ISPQKWNEVNVLDYLKRVKASNLENLMFFT 1521
Query: 237 SVLCIEMYVWDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTTTEVDAFPLEFV 296
++ +E+ + G K ++ +I + +L ++ N + E+
Sbjct: 1522 NIDSLEVSILPVGSKKLEQ----------QISIQKKSSLSLITNQYNNLMNIPTQASEY- 1570
Query: 297 TEAVRGVETVRQVDRFYIVQTMASASSRIGSFAITASKEY-----DIQLLPWASIAACIS 351
T + E + +++ I Q + + + ++ + + +A +
Sbjct: 1571 TFTIIPSEKSKITEKYIIGQVIEEDFKDPSEYPDNKALKFLSIYNNEKRKSVGGVAFKLP 1630
Query: 352 DNSLNNDVLRTGQAFCFLPL-PVRTGLSVQVNGFFEVSSNR-------RGIWYGDDMDRS 403
D SL ++ T ++FC+LP + + + V ++ F +S+R Y + S
Sbjct: 1631 DFSL-SEYKFTPKSFCYLPYKDLISNIPVHIHANFSTTSSRDILENAKSSNLYNIEEILS 1689
Query: 404 GKVRSI----------WNRLLLEDLVAPAFVHML----------HGVKELLGPTDIYYSL 443
KV + WN+L++ +++AP +++ L + + ++ + YYS
Sbjct: 1690 KKVNQVIQQSDSFQLCWNQLIVTEIIAPLYINTLTLFKNKYIKGNDIDKISKYHNFYYSR 1749
Query: 444 WP----TGSFEEPWSILVQQIY--INICNAPVIYSNLGGGRWVSPSEAFLHDEKFTK--- 494
+P + S +L + Y +N N+ V G SP + F D F
Sbjct: 1750 FPVLSDSLSNHSILEMLANKFYSLVNSENSDVFIHYPGVEIKKSPKDTFYADLGFLSNPY 1809
Query: 495 SKDLSLALMQLGMPVVHLPNSLF 517
S + + LG V P ++
Sbjct: 1810 SASILKCISYLGFNVNICPTDIY 1832
Score = 103 bits (258), Expect = 5e-20
Identities = 85/282 (30%), Positives = 136/282 (48%), Gaps = 25/282 (8%)
Query: 1342 VHGNISNDVAEKLGVRSLRRMLLAESADSMNFGLSGAAEAFGQHEALTTRLKHILEMYAD 1401
+H IS + A KL + L +++ ++ A +FGQ E L RLK IL Y
Sbjct: 1260 LHNKISENTASKLNITKLSQLIQSQVAFD---------NSFGQKEELVDRLKQILHDYKV 1310
Query: 1402 GPGTLFELVQNAEDAGASEVIFLLD----KSQYGTS----SVLSPEMADWQGPALYCFND 1453
L E+VQNA DAG++EV +LD K Q+ S + +++ + +L +N+
Sbjct: 1311 EV-FLNEMVQNAHDAGSTEVKLILDCNSLKQQFLKENPEISTVCKDLSSYFESSLLFYNN 1369
Query: 1454 SVFTPQDLYAISRIGQESKLEKAFAIGRFGLGFNCVYHFTDIPMFVSGENIVMFDPHASN 1513
SVFT +D+ + + K + IG+ GLG N +Y F+D P +SGE +++FDP ++
Sbjct: 1370 SVFTEKDIKNVQVMSASIKKQDEKCIGQHGLGINSMYSFSDCPCILSGEYLMIFDPFVTH 1429
Query: 1514 L-PGISPSHPGLRIKFAGRKILEQFPDQF---SSLLHFGCDLQHPFPGTLFRFPLRTAGV 1569
+ I+ SH G + K + K ++ F S+L F D F GT+ R PLR
Sbjct: 1430 IGQSINYSH-GAKYKISQYKTYLKYFKPFQHLQSILGFDLD-DGKFNGTIIRLPLRKTLN 1487
Query: 1570 ASRSQIKKEVYTPEDVRSLFAAFSEVVSETLLFLRNVKSISI 1611
R I + + +V E L+F N+ S+ +
Sbjct: 1488 DDRF-ISPQKWNEVNVLDYLKRVKASNLENLMFFTNIDSLEV 1528
Score = 42.0 bits (97), Expect = 0.25
Identities = 24/78 (30%), Positives = 43/78 (54%), Gaps = 3/78 (3%)
Query: 1771 FEGRAFCFLPLP-ISTGLPAHVNAYFELSSNRRDIWFG-SDMTGGGRKRS-DWNIYLLEN 1827
F+G+ F FLP+ + +P HVN YF LS+ R +I + +++ S WN+++ E
Sbjct: 354 FKGKPFTFLPIGGLVYDIPLHVNGYFRLSNARDNIIYSLTEVEEASESLSKQWNMFISET 413
Query: 1828 VVAPAYGRLLEKVALEIG 1845
++ Y + L+ + L G
Sbjct: 414 IIPYFYVKSLQYLKLNYG 431
Score = 37.7 bits (86), Expect = 4.8
Identities = 51/240 (21%), Positives = 99/240 (41%), Gaps = 35/240 (14%)
Query: 729 VQDILVKIGCHILKPGYVVEHPDLFSYLCGGNAAGVLESIFNAFSSAENMQVSFSSLIAE 788
++ IL K+ +++K G+ + L GNA I + N+ SL ++
Sbjct: 726 IEPILNKLKIYLIKEGHQINS------LLDGNAQ---IPILLGYLQRVNL-----SLDSK 771
Query: 789 ERNELRRFLLDPQWYVGHSMDEFNIRFCRRLPIYQVYHREP------TQDSQFSDLENPR 842
E ++LR FL++ + + S D +I + LPI+ T S D E
Sbjct: 772 EIDKLRIFLVESMFQISLSQDYTSIFY--NLPIHPCIGNSNQKFSSITTSSYCVDYEKID 829
Query: 843 KYLPPLDVPEFILVGIEFIVRSSNTEEDILSRYYGVERMGKAQFYKKHVFDRVGELQAED 902
+Y ++P L+ + + + N + I +R + G+ + Y+ ++ + +
Sbjct: 830 QY----EIPGLKLIKVNELTKYRNLFDTIPAR---IILKGEKEVYRFYLIQNISSFELNH 882
Query: 903 RDSIMLSVLQNLPLLSLEDASIRDLLRNLKFIPTVIGTLKCPSVLY--DPRNEEIYALLE 960
+ +++N L + LR L+FIP+ G P Y DP +E+ +E
Sbjct: 883 S----IEIIKNFLTLYSNHYTNDSELRKLQFIPSENGVYSTPDSFYVLDPLEKELIRKIE 938
>ref|NP_766397.1| hypothetical protein LOC239128 [Mus musculus]
gi|26338143|dbj|BAC32757.1| unnamed protein product [Mus
musculus]
Length = 531
Score = 124 bits (311), Expect = 4e-26
Identities = 129/502 (25%), Positives = 216/502 (42%), Gaps = 55/502 (10%)
Query: 171 DQFSPYCA-FGCDMQS----PFAGTLFRFPLRNADQASRSKLSRQAYTPEDISSMFVQLF 225
DQF+P+ FG ++ F GT FRFPLR S+LS YT + + +F
Sbjct: 32 DQFAPFIGVFGSTKETFTNGSFPGTFFRFPLR----LQPSQLSSNLYTKQKVLELFDSFR 87
Query: 226 EEGVLTLLFLKSVLCIEMYVWDAGEPKPKKIHSCSVSSVSDDTIWHRQALLRLSKSLNTT 285
+ LLFLKSV + ++V +A + V++ + + H + +
Sbjct: 88 ADADTVLLFLKSVQAVSLHVREADGTEKLVFR---VTASENKALKHERPNSIKILGTAIS 144
Query: 286 TEVDAFPLEFVTEAVRGVETVRQVDRFYIVQ-TMASASSRIGSFAITASKEY---DIQLL 341
P VT + V + + Q T + +G I++ + +++ +
Sbjct: 145 NYCKKIPSNSVTCVTYHINIVLEDESTKDAQKTSWLVCNSVGGRGISSKLDSLADELKFV 204
Query: 342 PWASIAACISDNSLNNDVLR--TGQAFCFLPLPV----RTGLSVQVNGFFEVSSNRRGIW 395
P +A +S N + +G+AFCFLPLP RTGL V ++GFF ++ NRR I
Sbjct: 205 PIIGLAMPLSGKDEENGAISDFSGKAFCFLPLPPGEESRTGLPVHISGFFGLTDNRRSIK 264
Query: 396 YGDDMDRSGKVRSIWNRLLLEDLVAPAFVHM-LHGVKELLG--------PTDIYYSLWPT 446
+ ++D+ ++WN L+ ++V + + L +K L D Y LWP
Sbjct: 265 W-RELDQWRDPAALWNEYLIVNVVPKTYATLILDSIKRLETEKSSDFPLSVDTIYKLWPE 323
Query: 447 GS-FEEPWSILVQQIYINICNAPVIYSNLGGGRWVSPSEAFLH--DEKFTKSKDLSLALM 503
S + W ++ ++ + VIYS GG WV + D ++ + L
Sbjct: 324 ASKVKAHWHPVLGPLFSELFQHAVIYSI--GGEWVKLEQVHFSELDGSLESTRSVLNYLQ 381
Query: 504 QLGMPVVHLPNSLFDMLLKYNSS--------KVITPGTVRQFLRECESCNHLSRA-HKLL 554
G + +P +L + +S + +TP VRQ LR+C HL A KL
Sbjct: 382 SSGKQIAKVPGNLAAAVQLSAASATSSASPVRKVTPAWVRQVLRKCA---HLGSAEEKLH 438
Query: 555 LLEYCLEDLVDDDVGKAAYNLPLLPLANGNFASFLE--ASKGIPYFICDELEYKLLEPVS 612
LLE+ L D ++ L LLPL +G F F + + + Y +E L +
Sbjct: 439 LLEFVLSDQAYSEL----LGLELLPLQSGAFVPFSSSVSDQDVVYITSEEFPRSLFPGLE 494
Query: 613 DRVIDQSIPPNILTRLSGIAMS 634
R+I +++ P++L L A +
Sbjct: 495 ARLILENLKPHLLAALKEAAQT 516
Score = 115 bits (288), Expect = 2e-23
Identities = 129/515 (25%), Positives = 221/515 (42%), Gaps = 83/515 (16%)
Query: 1532 KILEQFPDQFSSLLH-FGCDLQH----PFPGTLFRFPLRTAGVASRSQIKKEVYTPEDVR 1586
K + + PDQF+ + FG + FPGT FRFPLR SQ+ +YT + V
Sbjct: 25 KEINELPDQFAPFIGVFGSTKETFTNGSFPGTFFRFPLRL----QPSQLSSNLYTKQKVL 80
Query: 1587 SLFAAFSEVVSETLLFLRNVKSISIFLKEGTGHEMRLLHRVSRASLGESEIGSAEVQDVF 1646
LF +F LLFL++V+++S+ ++E G E +L+ RV+ + A +
Sbjct: 81 ELFDSFRADADTVLLFLKSVQAVSLHVREADGTE-KLVFRVTASE------NKALKHERP 133
Query: 1647 NFFKEDRLVGMNRAQFLKKLSLSIDRDLPYKCQKILITEQGTHGRNSHYWIMTECLGGGN 1706
N K ++G + + KK+ + + Y I++ ++ T W++ +GG
Sbjct: 134 NSIK---ILGTAISNYCKKIPSNSVTCVTYHI-NIVLEDESTKDAQKTSWLVCNSVGGRG 189
Query: 1707 VLKGTSEASTSNSHNFVPWACVAAYLNSVKHGEDLVDSAEVEDDCLVSSDLFQFASLPMH 1766
+ + S ++ FVP +A L+ G+D E++ +S
Sbjct: 190 I--SSKLDSLADELKFVPIIGLAMPLS----GKD-------EENGAIS------------ 224
Query: 1767 PRENFEGRAFCFLPLP----ISTGLPAHVNAYFELSSNRRDI-WFGSDMTGGGRKRSDWN 1821
+F G+AFCFLPLP TGLP H++ +F L+ NRR I W ++ + WN
Sbjct: 225 ---DFSGKAFCFLPLPPGEESRTGLPVHISGFFGLTDNRRSIKW--RELDQWRDPAALWN 279
Query: 1822 IYLLENVVAPAYGRL----LEKVALEIGPCY-----LFFSLWPKTLGLEP-WASVIRKLY 1871
YL+ NVV Y L ++++ E + + LWP+ ++ W V+ L+
Sbjct: 280 EYLIVNVVPKTYATLILDSIKRLETEKSSDFPLSVDTIYKLWPEASKVKAHWHPVLGPLF 339
Query: 1872 QFVAEFNLRVLYTEARGGQWISTKHAIFP--DFSFPKADELIKALSGASLPVITLPQSLL 1929
+ F V+Y + GG+W+ + F D S ++ L + + +P +L
Sbjct: 340 SEL--FQHAVIY--SIGGEWVKLEQVHFSELDGSLESTRSVLNYLQSSGKQIAKVPGNLA 395
Query: 1930 ERFMEICPS-------LHFLKPKLLRTLLIRRKREFKDRDAMILTLEYCLHDFEESMQFD 1982
S + + P +R +L R+ + + LE+ L D +
Sbjct: 396 AAVQLSAASATSSASPVRKVTPAWVRQVL-RKCAHLGSAEEKLHLLEFVLSD----QAYS 450
Query: 1983 TLGGLPLLPLADGSFTSIEMKGIGERVYIARGDEY 2017
L GL LLPL G+F + V +E+
Sbjct: 451 ELLGLELLPLQSGAFVPFSSSVSDQDVVYITSEEF 485
>dbj|BAC03486.1| unnamed protein product [Homo sapiens]
Length = 327
Score = 97.8 bits (242), Expect = 4e-18
Identities = 85/298 (28%), Positives = 139/298 (46%), Gaps = 36/298 (12%)
Query: 362 TGQAFCFLPLPV----RTGLSVQVNGFFEVSSNRRGIWYGDDMDRSGKVRSIWNRLLLED 417
+G+AFCFLPLP TGL V ++GFF ++ NRR I + ++D+ ++WN L+ +
Sbjct: 18 SGKAFCFLPLPPGEESSTGLPVHISGFFGLTDNRRSIKW-RELDQWRDPAALWNEFLVMN 76
Query: 418 LVAPAFVHM-LHGVKELLG--------PTDIYYSLWPTGS-FEEPWSILVQQIYINICNA 467
+V A+ + L +K L D+ Y LWP S + W +++ ++ +
Sbjct: 77 VVPKAYATLILDSIKRLEMEKSSDFPLSVDVIYKLWPEASKVKVHWQPVLEPLFSELLQN 136
Query: 468 PVIYSNLGGGRWVSPSEAFLH--DEKFTKSKDLSLALMQLGMPVVHLPNSLFDMLLKYNS 525
VIYS WV + + DE +K + L G + +P ++ D ++ +
Sbjct: 137 AVIYSI--SCDWVRLEQVYFSELDENLEYTKTVLNYLQSSGKQIAKVPGNV-DAAVQLTA 193
Query: 526 S------KVITPGTVRQFLRECESCNHLSRA-HKLLLLEYCLEDLVDDDVGKAAYNLPLL 578
+ + +TP VRQ LR+C HL A KL LLE+ L D ++ L LL
Sbjct: 194 ASGTTPVRKVTPAWVRQVLRKCA---HLGCAEEKLHLLEFVLSDQAYSEL----LGLELL 246
Query: 579 PLANGNFASFLE--ASKGIPYFICDELEYKLLEPVSDRVIDQSIPPNILTRLSGIAMS 634
PL NGNF F + + + Y E L + R I ++ P+++ L A +
Sbjct: 247 PLQNGNFVPFSSSVSDQDVIYITSAEYPRSLFPSLEGRFILDNLKPHLVAALKEAAQT 304
Score = 65.9 bits (159), Expect = 2e-08
Identities = 67/269 (24%), Positives = 118/269 (42%), Gaps = 32/269 (11%)
Query: 1770 NFEGRAFCFLPLP----ISTGLPAHVNAYFELSSNRRDI-WFGSDMTGGGRKRSDWNIYL 1824
+F G+AFCFLPLP STGLP H++ +F L+ NRR I W ++ + WN +L
Sbjct: 16 DFSGKAFCFLPLPPGEESSTGLPVHISGFFGLTDNRRSIKW--RELDQWRDPAALWNEFL 73
Query: 1825 LENVVAPAYGRL----LEKVALEIGPCY-----LFFSLWPKTLGLE-PWASVIRKLYQFV 1874
+ NVV AY L ++++ +E + + + LWP+ ++ W V+ L+ +
Sbjct: 74 VMNVVPKAYATLILDSIKRLEMEKSSDFPLSVDVIYKLWPEASKVKVHWQPVLEPLFSEL 133
Query: 1875 AEFNLRVLYTEARGGQWISTKHAIFP--DFSFPKADELIKALSGASLPVITLPQSLLERF 1932
+ V+Y+ + W+ + F D + ++ L + + +P ++
Sbjct: 134 LQ--NAVIYSIS--CDWVRLEQVYFSELDENLEYTKTVLNYLQSSGKQIAKVPGNVDAAV 189
Query: 1933 MEICPS----LHFLKPKLLRTLLIRRKREFKDRDAMILTLEYCLHDFEESMQFDTLGGLP 1988
S + + P +R +L R+ + + LE+ L D + L GL
Sbjct: 190 QLTAASGTTPVRKVTPAWVRQVL-RKCAHLGCAEEKLHLLEFVLSD----QAYSELLGLE 244
Query: 1989 LLPLADGSFTSIEMKGIGERVYIARGDEY 2017
LLPL +G+F + V EY
Sbjct: 245 LLPLQNGNFVPFSSSVSDQDVIYITSAEY 273
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.321 0.139 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,055,025,014
Number of Sequences: 2540612
Number of extensions: 178293779
Number of successful extensions: 355571
Number of sequences better than 10.0: 63
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 354829
Number of HSP's gapped (non-prelim): 314
length of query: 2349
length of database: 863,360,394
effective HSP length: 145
effective length of query: 2204
effective length of database: 494,971,654
effective search space: 1090917525416
effective search space used: 1090917525416
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 84 (37.0 bits)
Lotus: description of TM0237.12