BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0057b.8
(558 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|AAD32285.2| putative poly(ADP-ribose) glycohydrolase [Arabido... 529 e-149
dbj|BAD95273.1| poly(ADP-ribose) like glycohydrolase [Arabidopsi... 529 e-148
gb|AAQ56822.1| At2g31870 [Arabidopsis thaliana] gi|18252209|gb|A... 462 e-128
ref|NP_973578.1| poly (ADP-ribose) glycohydrolase (PARG) family ... 458 e-127
pir||B84726 probable poly(ADP-ribose) glycohydrolase [imported] ... 431 e-119
gb|AAD32286.1| putative poly(ADP-ribose) glycohydrolase [Arabido... 309 1e-82
ref|XP_624332.1| PREDICTED: similar to CG14001-PA [Apis mellifera] 222 2e-56
ref|NP_477321.1| CG2864-PA [Drosophila melanogaster] gi|7290430|... 216 2e-54
emb|CAB10913.1| EG:114E2.1 [Drosophila melanogaster] gi|15292221... 216 2e-54
gb|EAL32079.1| GA15492-PA [Drosophila pseudoobscura] 211 6e-53
gb|AAB61614.1| poly(ADP-ribose) glycohydrolase [Homo sapiens] gi... 202 2e-50
gb|AAH50560.1| PARG protein [Homo sapiens] gi|32455201|gb|AAP833... 202 2e-50
emb|CAI15135.1| poly (ADP-ribose) glycohydrolase [Homo sapiens] 202 2e-50
gb|AAT66422.1| poly (ADP-ribose) glycohydrolase [Homo sapiens] 202 2e-50
gb|AAT66421.1| poly (ADP-ribose) glycohydrolase [Homo sapiens] 202 2e-50
emb|CAH90218.1| hypothetical protein [Pongo pygmaeus] 202 2e-50
gb|AAH52966.1| PARG protein [Homo sapiens] 200 9e-50
ref|XP_642024.1| hypothetical protein DDB0204317 [Dictyostelium ... 200 9e-50
emb|CAG05369.1| unnamed protein product [Tetraodon nigroviridis] 197 6e-49
emb|CAF98668.1| unnamed protein product [Tetraodon nigroviridis] 196 2e-48
>gb|AAD32285.2| putative poly(ADP-ribose) glycohydrolase [Arabidopsis thaliana]
gi|14701908|gb|AAK72256.1| poly(ADP-ribose)
glycohydrolase [Arabidopsis thaliana]
gi|18402797|ref|NP_565730.1| poly (ADP-ribose)
glycohydrolase (PARG) family protein [Arabidopsis
thaliana]
Length = 548
Score = 529 bits (1363), Expect = e-149
Identities = 274/466 (58%), Positives = 332/466 (70%), Gaps = 30/466 (6%)
Query: 98 EESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIVFL 157
+ES++WF E++PAL LLL+ PSLLE H+QNAD ++ ++TGLRLL+SQ+ GIVFL
Sbjct: 86 KESKRWFDEIIPALASLLLQFPSLLEVHFQNADNIVSG----IKTGLRLLNSQQAGIVFL 141
Query: 158 SQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHYFQR 217
SQELI ALL CSFFCLFP + R KHL INFD LF SLY YSQ QESKI+CI+HYF+R
Sbjct: 142 SQELIGALLACSFFCLFPDDNRGAKHLPVINFDHLFASLYISYSQSQESKIRCIMHYFER 201
Query: 218 ITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLSEAV 277
S +P G+VSFERK+ + P+AD WS S + LC F+VHS GLIEDQ A+
Sbjct: 202 FCSCVPIGIVSFERKIT---------AAPDADFWSKSDVSLCAFKVHSFGLIEDQPDNAL 252
Query: 278 EVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSSYTG 337
EVDFAN+YLGGG+L RGCVQEEIRFMI+PELI MLFLP M DNEAIEIVG ERFS YTG
Sbjct: 253 EVDFANKYLGGGSLSRGCVQEEIRFMINPELIAGMLFLPRMDDNEAIEIVGAERFSCYTG 312
Query: 338 YASSFRFSGNYVDERDVDTLGRRKTRIVAIDALCSPGMRQYRPKFLLREINKAFCGFLYG 397
YASSFRF+G Y+D++ +D RR+TRIVAIDALC+P MR ++ LLREINKA CGFL
Sbjct: 313 YASSFRFAGEYIDKKAMDPFKRRRTRIVAIDALCTPKMRHFKDICLLREINKALCGFLNC 372
Query: 398 SKHQLYQKIL--------------QEKGCPSTLFDAATSTPM---ETSEGKCSNHEIRDS 440
SK +Q I ++ G T A+ TP+ E + K +N+ IRD
Sbjct: 373 SKAWEHQNIFMDEGDNEIQLVRNGRDSGLLRTETTASHRTPLNDVEMNREKPANNLIRDF 432
Query: 441 QNDYHRMEQCNNIGVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFRLEALHN 500
+ E + GVATGNWGCG FGGDPE+K IQWLAASQ RPFI+YYTF +EAL N
Sbjct: 433 YVEGVDNEDHEDDGVATGNWGCGVFGGDPELKATIQWLAASQTRRPFISYYTFGVEALRN 492
Query: 501 IDKVAHWILSHRWTVGDLWNMLTEYSMNRSKGETNVGFLQWVLPSM 546
+D+V WILSH+WTVGDLWNM+ EYS R +T+VGF W+LPS+
Sbjct: 493 LDQVTKWILSHKWTVGDLWNMMLEYSAQRLYKQTSVGFFSWLLPSL 538
>dbj|BAD95273.1| poly(ADP-ribose) like glycohydrolase [Arabidopsis thaliana]
Length = 547
Score = 529 bits (1362), Expect = e-148
Identities = 275/465 (59%), Positives = 333/465 (71%), Gaps = 29/465 (6%)
Query: 98 EESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIVFL 157
+ES++WF E++PAL LLL+ PSLLE H+QNAD ++ ++TGLRLL+SQ+ GIVFL
Sbjct: 86 KESKRWFDEIIPALASLLLQFPSLLEVHFQNADNIVSG----IKTGLRLLNSQQAGIVFL 141
Query: 158 SQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHYFQR 217
SQELI ALL CSFFCLFP + R KHL INFD LF SLY YSQ QESKI+CI+HYF+R
Sbjct: 142 SQELIGALLACSFFCLFPDDNRGAKHLPIINFDHLFASLYISYSQSQESKIRCIMHYFER 201
Query: 218 ITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLSEAV 277
S +P G+VSFERK+ + P+AD WS S + LC F+VHS GLIEDQ A+
Sbjct: 202 FCSCVPIGIVSFERKIT---------AAPDADFWSKSDVSLCAFKVHSFGLIEDQPDNAL 252
Query: 278 EVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSSYTG 337
EVDFAN+YLGGG+L RGCVQEEIRFMI+PELI MLFLP M DNEAIEIVG ERFS YTG
Sbjct: 253 EVDFANKYLGGGSLSRGCVQEEIRFMINPELIAGMLFLPRMDDNEAIEIVGAERFSCYTG 312
Query: 338 YASSFRFSGNYVDERDVDTLGRRKTRIVAIDALCSPGMRQYRPKFLLREINKAFCGFLYG 397
YASSFRF+G Y+D++ +D RR+TRIVAIDALC+P MR ++ LLREINKA CGFL
Sbjct: 313 YASSFRFAGEYIDKKAMDPFKRRRTRIVAIDALCTPKMRHFKDICLLREINKALCGFLNC 372
Query: 398 SKHQLYQKILQEK----------GCPSTLFDAATS---TPM---ETSEGKCSNHEIRDSQ 441
SK +Q I ++ G S L T+ TP+ E + K +N+ IRD
Sbjct: 373 SKAWEHQNIFMDEGDNEIQLVRNGRDSGLLRTETTSHRTPLNDVEMNREKPANNLIRDFY 432
Query: 442 NDYHRMEQCNNIGVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFRLEALHNI 501
+ E + GVATGNWGCG FGGDPE+K IQWLAASQ RPFI+YYTF +EAL N+
Sbjct: 433 VEGVDNEDHEDDGVATGNWGCGVFGGDPELKATIQWLAASQTRRPFISYYTFGVEALRNL 492
Query: 502 DKVAHWILSHRWTVGDLWNMLTEYSMNRSKGETNVGFLQWVLPSM 546
D+V WILSH+WTVGDLWNM+ EYS R +T+VGF W+LPS+
Sbjct: 493 DQVTKWILSHKWTVGDLWNMMLEYSAQRLYKQTSVGFFSWLLPSL 537
>gb|AAQ56822.1| At2g31870 [Arabidopsis thaliana] gi|18252209|gb|AAL61937.1|
putative poly(ADP-ribose) glycohydrolase [Arabidopsis
thaliana] gi|30685093|ref|NP_850175.1| poly (ADP-ribose)
glycohydrolase (PARG) family protein [Arabidopsis
thaliana]
Length = 522
Score = 462 bits (1188), Expect = e-128
Identities = 244/450 (54%), Positives = 304/450 (67%), Gaps = 18/450 (4%)
Query: 98 EESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIVFL 157
EES +F EVVPAL LLL+LPS+LE HYQ AD VLD V++GLRLL QE GIV L
Sbjct: 88 EESANFFGEVVPALCRLLLQLPSMLEKHYQKADHVLDG----VKSGLRLLGPQEAGIVLL 143
Query: 158 SQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHYFQR 217
SQELIAALL CSFFCLFP +R K+LQ INF LF Y + KQE+KI+C+IHYF R
Sbjct: 144 SQELIAALLACSFFCLFPEVDRSLKNLQGINFSGLFSFPYMRHCTKQENKIKCLIHYFGR 203
Query: 218 ITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLSEAV 277
I MP G VSFERK+LPLE +SYP AD W+ S+ PLC E+H+SG IEDQ EA+
Sbjct: 204 ICRWMPTGFVSFERKILPLEYHPHFVSYPKADSWANSVTPLCSIEIHTSGAIEDQPCEAL 263
Query: 278 EVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSSYTG 337
EVDFA+EY GG L +QEEIRF+I+PELI M+FLP M NEAIEIVGVERFS YTG
Sbjct: 264 EVDFADEYFGGLTLSYDTLQEEIRFVINPELIAGMIFLPRMDANEAIEIVGVERFSGYTG 323
Query: 338 YASSFRFSGNYVDERDVDTLGRRKTRIVAIDALCSPGMRQYRPKFLLREINKAFCGFLYG 397
Y SF+++G+Y D +D+D RRKTR++AIDA+ PGM QY+ L+RE+NKAF G+++
Sbjct: 324 YGPSFQYAGDYTDNKDLDIFRRRKTRVIAIDAMPDPGMGQYKLDALIREVNKAFSGYMHQ 383
Query: 398 SKHQLYQKILQEKGCPST-LFDAATSTPMETSEGKCSNHEIRDSQNDYHRMEQCNNIGVA 456
K+ + K E L + S +E+S C +HE + IGVA
Sbjct: 384 CKYNIDVKHDPEASSSHVPLTSDSASQVIESSHRWCIDHEEK-------------KIGVA 430
Query: 457 TGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFRLEALHNIDKVAHWILSHRWTVG 516
TGNWGCG FGGDPE+K ++QWLA SQ+ RPF++YYTF L+AL N+++V + TVG
Sbjct: 431 TGNWGCGVFGGDPELKIMLQWLAISQSGRPFMSYYTFGLQALQNLNQVIEMVALQEMTVG 490
Query: 517 DLWNMLTEYSMNRSKGETNVGFLQWVLPSM 546
DLW L EYS R T +GF W++ S+
Sbjct: 491 DLWKKLVEYSSERLSRRTWLGFFSWLMTSL 520
>ref|NP_973578.1| poly (ADP-ribose) glycohydrolase (PARG) family protein [Arabidopsis
thaliana]
Length = 532
Score = 458 bits (1179), Expect = e-127
Identities = 244/460 (53%), Positives = 305/460 (66%), Gaps = 28/460 (6%)
Query: 98 EESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIVFL 157
EES +F EVVPAL LLL+LPS+LE HYQ AD VLD V++GLRLL QE GIV L
Sbjct: 88 EESANFFGEVVPALCRLLLQLPSMLEKHYQKADHVLDG----VKSGLRLLGPQEAGIVLL 143
Query: 158 SQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHYFQR 217
SQELIAALL CSFFCLFP +R K+LQ INF LF Y + KQE+KI+C+IHYF R
Sbjct: 144 SQELIAALLACSFFCLFPEVDRSLKNLQGINFSGLFSFPYMRHCTKQENKIKCLIHYFGR 203
Query: 218 ITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLSEAV 277
I MP G VSFERK+LPLE +SYP AD W+ S+ PLC E+H+SG IEDQ EA+
Sbjct: 204 ICRWMPTGFVSFERKILPLEYHPHFVSYPKADSWANSVTPLCSIEIHTSGAIEDQPCEAL 263
Query: 278 EVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSSYTG 337
EVDFA+EY GG L +QEEIRF+I+PELI M+FLP M NEAIEIVGVERFS YTG
Sbjct: 264 EVDFADEYFGGLTLSYDTLQEEIRFVINPELIAGMIFLPRMDANEAIEIVGVERFSGYTG 323
Query: 338 YASSFRFSGNYVDERDVDTLGRRKTRIVAIDALCSPGMRQYRPKFLLREINKAFCGFLYG 397
Y SF+++G+Y D +D+D RRKTR++AIDA+ PGM QY+ L+RE+NKAF G+++
Sbjct: 324 YGPSFQYAGDYTDNKDLDIFRRRKTRVIAIDAMPDPGMGQYKLDALIREVNKAFSGYMHQ 383
Query: 398 SKHQLYQKILQEKGCPS-----------TLFDAATSTPMETSEGKCSNHEIRDSQNDYHR 446
K+ + K E + L + S +E+S C +HE +
Sbjct: 384 CKYNIDVKHDPEASSSTKIKFVFAKQHVPLTSDSASQVIESSHRWCIDHEEK-------- 435
Query: 447 MEQCNNIGVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFRLEALHNIDKVAH 506
IGVATGNWGCG FGGDPE+K ++QWLA SQ+ RPF++YYTF L+AL N+++V
Sbjct: 436 -----KIGVATGNWGCGVFGGDPELKIMLQWLAISQSGRPFMSYYTFGLQALQNLNQVIE 490
Query: 507 WILSHRWTVGDLWNMLTEYSMNRSKGETNVGFLQWVLPSM 546
+ TVGDLW L EYS R T +GF W++ S+
Sbjct: 491 MVALQEMTVGDLWKKLVEYSSERLSRRTWLGFFSWLMTSL 530
>pir||B84726 probable poly(ADP-ribose) glycohydrolase [imported] - Arabidopsis
thaliana
Length = 997
Score = 431 bits (1108), Expect = e-119
Identities = 239/432 (55%), Positives = 291/432 (67%), Gaps = 44/432 (10%)
Query: 98 EESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIVFL 157
+ES++WF E++PAL LLL+ PSLLE H+QNAD ++ ++TGLRLL+SQ+ GIVFL
Sbjct: 86 KESKRWFDEIIPALASLLLQFPSLLEVHFQNADNIVSG----IKTGLRLLNSQQAGIVFL 141
Query: 158 SQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHYFQR 217
SQELI ALL CSFFCLFP + R KHL INFD L SLY YSQ QESKI+CI+HYF+R
Sbjct: 142 SQELIGALLACSFFCLFPDDNRGAKHLPVINFDHL--SLYISYSQSQESKIRCIMHYFER 199
Query: 218 ITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLSEAV 277
S +P G+VSFERK+ + P+AD WS S + L Q A+
Sbjct: 200 FCSCVPIGIVSFERKIT---------AAPDADFWSKSDVSLY------------QPDNAL 238
Query: 278 EVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSSYTG 337
EVDFAN+YLGGG+L RGCVQEEIRFMI+PELI MLFLP M DNEAIEIVG ERFS YTG
Sbjct: 239 EVDFANKYLGGGSLSRGCVQEEIRFMINPELIAGMLFLPRMDDNEAIEIVGAERFSCYTG 298
Query: 338 YASSFRFSGNYVDERDVDTLGRRKTRIVAIDALCSPGMRQYRPKFLLREINKAFCGFLYG 397
YASSFRF+G Y+D++ +D RR+TRIVAIDALC+P MR ++ LLREINKA CGFL
Sbjct: 299 YASSFRFAGEYIDKKAMDPFKRRRTRIVAIDALCTPKMRHFKDICLLREINKALCGFLNC 358
Query: 398 SKHQLYQKIL--------------QEKGCPSTLFDAATSTPM---ETSEGKCSNHEIRDS 440
SK +Q I ++ G T A+ TP+ E + K +N+ IRD
Sbjct: 359 SKAWEHQNIFMDEGDNEIQLVRNGRDSGLLRTETTASHRTPLNDVEMNREKPANNLIRDF 418
Query: 441 QNDYHRMEQCNNIGVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFRLEALHN 500
+ E + GVATGNWGCG FGGDPE+K IQWLAASQ RPFI+YYTF +EAL N
Sbjct: 419 YVEGVDNEDHEDDGVATGNWGCGVFGGDPELKATIQWLAASQTRRPFISYYTFGVEALRN 478
Query: 501 IDKVAHWILSHR 512
+D++ LS R
Sbjct: 479 LDQLPPTKLSSR 490
Score = 401 bits (1030), Expect = e-110
Identities = 217/397 (54%), Positives = 266/397 (66%), Gaps = 28/397 (7%)
Query: 98 EESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIVFL 157
EES +F EVVPAL LLL+LPS+LE HYQ AD VLD V++GLRLL QE GIV L
Sbjct: 606 EESANFFGEVVPALCRLLLQLPSMLEKHYQKADHVLDG----VKSGLRLLGPQEAGIVLL 661
Query: 158 SQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHYFQR 217
SQELIAALL CSFFCLFP +R K+LQ INF LF Y + KQE+KI+C+IHYF R
Sbjct: 662 SQELIAALLACSFFCLFPEVDRSLKNLQGINFSGLFSFPYMRHCTKQENKIKCLIHYFGR 721
Query: 218 ITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLSEAV 277
I MP G VSFERK+LPLE +SYP AD W+ S+ PLC E+H+SG IEDQ EA+
Sbjct: 722 ICRWMPTGFVSFERKILPLEYHPHFVSYPKADSWANSVTPLCSIEIHTSGAIEDQPCEAL 781
Query: 278 EVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSSYTG 337
EVDFA+EY GG L +QEEIRF+I+PELI M+FLP M NEAIEIVGVERFS YTG
Sbjct: 782 EVDFADEYFGGLTLSYDTLQEEIRFVINPELIAGMIFLPRMDANEAIEIVGVERFSGYTG 841
Query: 338 YASSFRFSGNYVDERDVDTLGRRKTRIVAIDALCSPGMRQYRPKFLLREINKAFCGFLYG 397
Y SF+++G+Y D +D+D RRKTR++AIDA+ PGM QY+ L+RE+NKAF G+++
Sbjct: 842 YGPSFQYAGDYTDNKDLDIFRRRKTRVIAIDAMPDPGMGQYKLDALIREVNKAFSGYMHQ 901
Query: 398 SKHQLYQKILQEKGCPS-----------TLFDAATSTPMETSEGKCSNHEIRDSQNDYHR 446
K+ + K E + L + S +E+S C +HE +
Sbjct: 902 CKYNIDVKHDPEASSSTKIKFVFAKQHVPLTSDSASQVIESSHRWCIDHEEK-------- 953
Query: 447 MEQCNNIGVATGNWGCGAFGGDPEVKTIIQWLAASQA 483
IGVATGNWGCG FGGDPE+K ++QWLA SQA
Sbjct: 954 -----KIGVATGNWGCGVFGGDPELKIMLQWLAISQA 985
>gb|AAD32286.1| putative poly(ADP-ribose) glycohydrolase [Arabidopsis thaliana]
gi|25408190|pir||A84726 probable poly(ADP-ribose)
glycohydrolase [imported] - Arabidopsis thaliana
Length = 364
Score = 309 bits (792), Expect = 1e-82
Identities = 194/409 (47%), Positives = 250/409 (60%), Gaps = 50/409 (12%)
Query: 98 EESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIVFL 157
EES +WF E +PA+ LLLR PSLLE+HY N+D +++ +TGLR+L + GIVFL
Sbjct: 4 EESSRWFNEFLPAMACLLLRFPSLLESHYLNSDNLING----TKTGLRVLVPNKAGIVFL 59
Query: 158 SQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDY-YSQKQESKIQCIIHYFQ 216
SQELI ALL CSFFCLFPV++R HL INFD+LFGSL + ++ QE+KI+CIIHYFQ
Sbjct: 60 SQELIGALLSCSFFCLFPVDDRGSNHLPIINFDKLFGSLINTGRNEHQENKIKCIIHYFQ 119
Query: 217 RITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLSEA 276
R++S++ G VSFERK+L LE D S + W S + LC EV +SGLIEDQ EA
Sbjct: 120 RLSSSISPGFVSFERKILSLEQDS---STLDEGFWGKSTVNLCPVEVRTSGLIEDQSVEA 176
Query: 277 VEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSSYT 336
+EVDFAN+ LGGGALR+GCVQEEIRFMI+PELIV MLFLP+M EAIE+VG ERFS YT
Sbjct: 177 LEVDFANKNLGGGALRKGCVQEEIRFMINPELIVGMLFLPTMEVTEAIEVVGAERFSLYT 236
Query: 337 GYASSFRFSGNYVDERDVDTLGRRKTRIVAIDALCSPGMRQYRPKFLLREINKAFCGFLY 396
G FR + KTRIVAIDAL PG+ QY+ + LL +
Sbjct: 237 G---CFR---------------KAKTRIVAIDALRHPGVSQYKLESLLSVL--------- 269
Query: 397 GSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRME-QCNNIGV 455
IL G P L+ + S ++ EI S ++ + +N+ +
Sbjct: 270 ---------ILSSSGRPIRLYMGSVS--LQGIGDVVLMVEILSSSLFFNGLRFHRSNLYL 318
Query: 456 ATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFRLEALHNIDKV 504
+ C P V + L + QA RPF++YYTF EAL N+++V
Sbjct: 319 FSPLIACNY---QPMVVVWLTTLHSFQARRPFMSYYTFGFEALQNLNQV 364
>ref|XP_624332.1| PREDICTED: similar to CG14001-PA [Apis mellifera]
Length = 3681
Score = 222 bits (566), Expect = 2e-56
Identities = 156/446 (34%), Positives = 228/446 (50%), Gaps = 88/446 (19%)
Query: 98 EESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIVFL 157
EE+ +F+ ++P + L L+LP L V + LL G + L
Sbjct: 184 EEANIFFEVLMPKMVQLALQLPVL------------------VTGSVPLLKRHTNGAISL 225
Query: 158 SQELIAALLVCSFFCLFP------VNERYGKHLQSINFDELFGSLYDYYSQKQES---KI 208
SQ IA+LL +FFC FP YGK+ INF+ LF + + K ES K+
Sbjct: 226 SQLQIASLLANAFFCTFPRRNSTNPQSEYGKY-PYINFNRLFSAYKEGKWNKCESVMEKM 284
Query: 209 QCIIHYFQRITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGL 268
+CI HYF+R+TS P+GVV+ +R+ +P D W + L + S G
Sbjct: 285 KCIFHYFRRVTSKAPEGVVTIQRRYIPKSD---------CPKWDEQVQKLLPLHITSKGT 335
Query: 269 IEDQLSEAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVG 328
IE + + ++VDFAN+Y+GGG L GCVQEEIRF+I PEL+V ML + D EA+ + G
Sbjct: 336 IETEGTGFLQVDFANKYVGGGVLGLGCVQEEIRFVICPELMVTMLVTEELDDTEALIVSG 395
Query: 329 VERFSSYTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREI 387
+ER+S Y GY+++F++ G+YVDE D+ GRR T IVAIDAL + Q+ + RE+
Sbjct: 396 IERYSKYKGYSNTFKWVGDYVDETPKDSSGRRLTSIVAIDALYFTHTQSQFNINNITREL 455
Query: 388 NKAFCGFLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRM 447
NKA+ GF+ GC EG S+N
Sbjct: 456 NKAYVGFV---------------GC----------------EG---------SKN----- 470
Query: 448 EQCNNIGVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFRLEALHN-IDKVAH 506
N VATGNWGCGAF G+P++K ++Q +AA+ A R + Y+TF L + I ++
Sbjct: 471 ---NLPAVATGNWGCGAFRGNPKLKVLLQLMAAAVAGRSMV-YFTFGDTNLRDAIAEMYM 526
Query: 507 WILSHRWTVGDLWNMLTEYSMNRSKG 532
+ H + ++++L +Y S G
Sbjct: 527 HFVKHEINIAHIFSLLVQYQEFASTG 552
>ref|NP_477321.1| CG2864-PA [Drosophila melanogaster] gi|7290430|gb|AAF45886.1|
CG2864-PA [Drosophila melanogaster]
gi|55583792|sp|O46043|PARG_DROME Poly(ADP-ribose)
glycohydrolase gi|3388157|gb|AAC28734.1|
poly(ADP-ribose) glycohydrolase [Drosophila
melanogaster]
Length = 768
Score = 216 bits (549), Expect = 2e-54
Identities = 156/440 (35%), Positives = 219/440 (49%), Gaps = 91/440 (20%)
Query: 99 ESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIVFLS 158
E+R +F++++P + L LRLP L+++ + LL + + LS
Sbjct: 204 ETRVFFEDLLPRIIRLALRLPDLIQSP------------------VPLLKHHKNASLSLS 245
Query: 159 QELIAALLVCSFFCLFPVNERYGKHLQSINFDEL-FGSLYDYYSQKQESKIQCIIHYFQR 217
Q+ I+ LL +F C FP + + F ++ F LY K++CI+HYF+R
Sbjct: 246 QQQISCLLANAFLCTFPRRNTLKRKSEYSTFPDINFNRLYQSTGPAVLEKLKCIMHYFRR 305
Query: 218 I------TSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVH--SSGLI 269
+ SN+P GVV+F R+ L + I WS S PL +H + G I
Sbjct: 306 VCPTERDASNVPTGVVTFVRRS-GLPEHLID--------WSQSAAPLGDVPLHVDAEGTI 356
Query: 270 EDQLSEAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGV 329
ED+ ++VDFAN+YLGGG L GCVQEEIRF+I PEL+V LF + EA+ ++G
Sbjct: 357 EDEGIGLLQVDFANKYLGGGVLGHGCVQEEIRFVICPELLVGKLFTECLRPFEALVMLGA 416
Query: 330 ERFSSYTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREIN 388
ER+S+YTGYA SF +SGN+ D D+ GRR+T IVAIDAL + QYR + RE+N
Sbjct: 417 ERYSNYTGYAGSFEWSGNFEDSTPRDSSGRRQTAIVAIDALHFAQSHHQYREDLMERELN 476
Query: 389 KAFCGFLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRME 448
KA+ G H + T P
Sbjct: 477 KAYI----GFVHWM-----------------VTPPP------------------------ 491
Query: 449 QCNNIGVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFRLEALHNIDKVAHWI 508
GVATGNWGCGAFGGD +K ++Q + +Q RP +AYYTF + D W+
Sbjct: 492 -----GVATGNWGCGAFGGDSYLKALLQLMVCAQLGRP-LAYYTFGNVEFRD-DFHEMWL 544
Query: 509 L--SHRWTVGDLWNMLTEYS 526
L + TV LW++L YS
Sbjct: 545 LFRNDGTTVQQLWSILRSYS 564
>emb|CAB10913.1| EG:114E2.1 [Drosophila melanogaster] gi|15292221|gb|AAK93379.1|
LD42380p [Drosophila melanogaster]
Length = 723
Score = 216 bits (549), Expect = 2e-54
Identities = 156/440 (35%), Positives = 219/440 (49%), Gaps = 91/440 (20%)
Query: 99 ESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIVFLS 158
E+R +F++++P + L LRLP L+++ + LL + + LS
Sbjct: 159 ETRVFFEDLLPRIIRLALRLPDLIQSP------------------VPLLKHHKNASLSLS 200
Query: 159 QELIAALLVCSFFCLFPVNERYGKHLQSINFDEL-FGSLYDYYSQKQESKIQCIIHYFQR 217
Q+ I+ LL +F C FP + + F ++ F LY K++CI+HYF+R
Sbjct: 201 QQQISCLLANAFLCTFPRRNTLKRKSEYSTFPDINFNRLYQSTGPAVLEKLKCIMHYFRR 260
Query: 218 I------TSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVH--SSGLI 269
+ SN+P GVV+F R+ L + I WS S PL +H + G I
Sbjct: 261 VCPTERDASNVPTGVVTFVRRS-GLPEHLID--------WSQSAAPLGDVPLHVDAEGTI 311
Query: 270 EDQLSEAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGV 329
ED+ ++VDFAN+YLGGG L GCVQEEIRF+I PEL+V LF + EA+ ++G
Sbjct: 312 EDEGIGLLQVDFANKYLGGGVLGHGCVQEEIRFVICPELLVGKLFTECLRPFEALVMLGA 371
Query: 330 ERFSSYTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREIN 388
ER+S+YTGYA SF +SGN+ D D+ GRR+T IVAIDAL + QYR + RE+N
Sbjct: 372 ERYSNYTGYAGSFEWSGNFEDSTPRDSSGRRQTAIVAIDALHFAQSHHQYREDLMERELN 431
Query: 389 KAFCGFLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRME 448
KA+ G H + T P
Sbjct: 432 KAYI----GFVHWM-----------------VTPPP------------------------ 446
Query: 449 QCNNIGVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFRLEALHNIDKVAHWI 508
GVATGNWGCGAFGGD +K ++Q + +Q RP +AYYTF + D W+
Sbjct: 447 -----GVATGNWGCGAFGGDSYLKALLQLMVCAQLGRP-LAYYTFGNVEFRD-DFHEMWL 499
Query: 509 L--SHRWTVGDLWNMLTEYS 526
L + TV LW++L YS
Sbjct: 500 LFRNDGTTVQQLWSILRSYS 519
>gb|EAL32079.1| GA15492-PA [Drosophila pseudoobscura]
Length = 659
Score = 211 bits (536), Expect = 6e-53
Identities = 152/461 (32%), Positives = 227/461 (48%), Gaps = 90/461 (19%)
Query: 99 ESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIVFLS 158
E + +F++++P + L LRLP +++A L LL ++ L+
Sbjct: 139 EKKVFFEDLLPRIIRLALRLPDIVQA------------------SLPLLKQHTNSMITLT 180
Query: 159 QELIAALLVCSFFCLFPVNERYGKHLQSINFDEL-FGSLYDYYSQKQESKIQCIIHYFQR 217
Q+ I+ LL +F C +P + +F ++ F LY K++CI+HYF+R
Sbjct: 181 QQQISCLLANAFLCTYPRRNTLKLKSEYSSFPDINFNRLYQSSGSAVMEKLKCIMHYFRR 240
Query: 218 IT------SNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIED 271
I N+ G V+F R+ + + I N S +PL V+S+G IED
Sbjct: 241 ICPTERGDGNVSTGCVTFFRRSVKPDRTTIW----NEVTESLGDVPL---HVNSAGTIED 293
Query: 272 QLSEAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVER 331
Q ++VDFAN+YLGGG L GCVQEEIRF+I PEL+V LF + EA+ ++G ER
Sbjct: 294 QGLGLLQVDFANKYLGGGVLGHGCVQEEIRFVICPELMVSKLFTECLRPTEALMVLGAER 353
Query: 332 FSSYTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREINKA 390
+S+YTGYA SF +SGN+ D D+ RR+T IVAIDAL + QYR + RE+NKA
Sbjct: 354 YSNYTGYAGSFTWSGNHEDLTPRDSSRRRQTAIVAIDALQFANATHQYREDLVERELNKA 413
Query: 391 FCGFLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRMEQC 450
GF++ A +S P
Sbjct: 414 HTGFMH----------------------ALSSEPP------------------------- 426
Query: 451 NNIGVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTF-RLEALHNIDKVAHWIL 509
GVATGNWGCGAFGGD +K+++Q + + RP +AYYTF + + ++
Sbjct: 427 ---GVATGNWGCGAFGGDARLKSLLQLMVCATLHRP-LAYYTFGNIRLRDELHEMWQLFR 482
Query: 510 SHRWTVGDLWNMLT--EYSMNRSKGETNVGFLQWVLPSMYD 548
S TV LW +L +YS+ + +++ + P++YD
Sbjct: 483 SQGTTVRQLWTVLRRFDYSLRSNPSQSSQPAAK---PNLYD 520
>gb|AAB61614.1| poly(ADP-ribose) glycohydrolase [Homo sapiens]
gi|4505609|ref|NP_003622.1| poly (ADP-ribose)
glycohydrolase [Homo sapiens]
Length = 976
Score = 202 bits (515), Expect = 2e-50
Identities = 136/373 (36%), Positives = 192/373 (51%), Gaps = 62/373 (16%)
Query: 155 VFLSQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHY 214
+ +SQE IA+LL +FFC FP K S D F L++ S ++ K++ + Y
Sbjct: 623 ITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCY 682
Query: 215 FQRITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLS 274
F+R+T P G+V+F R+ LED +P W PL R V G IE+
Sbjct: 683 FRRVTEKKPTGLVTFTRQ--SLED------FPE---WERCEKPLTRLHVTYEGTIEENGQ 731
Query: 275 EAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSS 334
++VDFAN ++GGG G VQEEIRF+I+PELI+ LF + NE + I G E++S
Sbjct: 732 GMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNECLIITGTEQYSE 791
Query: 335 YTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREINKAFCG 393
YTGYA ++R+S ++ D + D RR T IVAIDAL + Q+ P+ + RE+NKA+CG
Sbjct: 792 YTGYAETYRWSRSHEDGSERDDCERRCTEIVAIDALHFRRYLDQFVPEKMRRELNKAYCG 851
Query: 394 FLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRMEQCNNI 453
FL P +SE N
Sbjct: 852 FL---------------------------RPGVSSE---------------------NLS 863
Query: 454 GVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTF-RLEALHNIDKVAHWILSHR 512
VATGNWGCGAFGGD +K +IQ LAA+ A R + Y+TF E + +I + ++ +
Sbjct: 864 AVATGNWGCGAFGGDARLKALIQILAAAAAERD-VVYFTFGDSELMRDIYSMHIFLTERK 922
Query: 513 WTVGDLWNMLTEY 525
TVGD++ +L Y
Sbjct: 923 LTVGDVYKLLLRY 935
>gb|AAH50560.1| PARG protein [Homo sapiens] gi|32455201|gb|AAP83314.1|
poly(ADP-ribose) glycohydrolase [Homo sapiens]
gi|56417893|sp|Q86W56|PARG_HUMAN Poly(ADP-ribose)
glycohydrolase
Length = 976
Score = 202 bits (514), Expect = 2e-50
Identities = 136/373 (36%), Positives = 192/373 (51%), Gaps = 62/373 (16%)
Query: 155 VFLSQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHY 214
+ +SQE IA+LL +FFC FP K S D F L++ S ++ K++ + Y
Sbjct: 623 ITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCY 682
Query: 215 FQRITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLS 274
F+R+T P G+V+F R+ LED +P W PL R V G IE+
Sbjct: 683 FRRVTEKKPTGLVTFTRQ--SLED------FPE---WERCEKPLTRLHVTYEGTIEENGQ 731
Query: 275 EAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSS 334
++VDFAN ++GGG G VQEEIRF+I+PELI+ LF + NE + I G E++S
Sbjct: 732 GMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNECLIITGTEQYSE 791
Query: 335 YTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREINKAFCG 393
YTGYA ++R+S ++ D + D RR T IVAIDAL + Q+ P+ + RE+NKA+CG
Sbjct: 792 YTGYAETYRWSRSHEDGSERDDWQRRCTEIVAIDALHFRRYLDQFVPEKMRRELNKAYCG 851
Query: 394 FLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRMEQCNNI 453
FL P +SE N
Sbjct: 852 FL---------------------------RPGVSSE---------------------NLS 863
Query: 454 GVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTF-RLEALHNIDKVAHWILSHR 512
VATGNWGCGAFGGD +K +IQ LAA+ A R + Y+TF E + +I + ++ +
Sbjct: 864 AVATGNWGCGAFGGDARLKALIQILAAAAAERD-VVYFTFGDSELMRDIYSMHIFLTERK 922
Query: 513 WTVGDLWNMLTEY 525
TVGD++ +L Y
Sbjct: 923 LTVGDVYKLLLRY 935
>emb|CAI15135.1| poly (ADP-ribose) glycohydrolase [Homo sapiens]
Length = 491
Score = 202 bits (514), Expect = 2e-50
Identities = 136/373 (36%), Positives = 192/373 (51%), Gaps = 62/373 (16%)
Query: 155 VFLSQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHY 214
+ +SQE IA+LL +FFC FP K S D F L++ S ++ K++ + Y
Sbjct: 138 ITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCY 197
Query: 215 FQRITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLS 274
F+R+T P G+V+F R+ LED +P W PL R V G IE+
Sbjct: 198 FRRVTEKKPTGLVTFTRQ--SLED------FPE---WERCEKPLTRLHVTYEGTIEENGQ 246
Query: 275 EAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSS 334
++VDFAN ++GGG G VQEEIRF+I+PELI+ LF + NE + I G E++S
Sbjct: 247 GMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNECLIITGTEQYSE 306
Query: 335 YTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREINKAFCG 393
YTGYA ++R+S ++ D + D RR T IVAIDAL + Q+ P+ + RE+NKA+CG
Sbjct: 307 YTGYAETYRWSRSHEDGSERDDWQRRCTEIVAIDALHFRRYLDQFVPEKMRRELNKAYCG 366
Query: 394 FLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRMEQCNNI 453
FL P +SE N
Sbjct: 367 FL---------------------------RPGVSSE---------------------NLS 378
Query: 454 GVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTF-RLEALHNIDKVAHWILSHR 512
VATGNWGCGAFGGD +K +IQ LAA+ A R + Y+TF E + +I + ++ +
Sbjct: 379 AVATGNWGCGAFGGDARLKALIQILAAAAAERD-VVYFTFGDSELMRDIYSMHIFLTERK 437
Query: 513 WTVGDLWNMLTEY 525
TVGD++ +L Y
Sbjct: 438 LTVGDVYKLLLRY 450
>gb|AAT66422.1| poly (ADP-ribose) glycohydrolase [Homo sapiens]
Length = 868
Score = 202 bits (514), Expect = 2e-50
Identities = 136/373 (36%), Positives = 192/373 (51%), Gaps = 62/373 (16%)
Query: 155 VFLSQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHY 214
+ +SQE IA+LL +FFC FP K S D F L++ S ++ K++ + Y
Sbjct: 515 ITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCY 574
Query: 215 FQRITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLS 274
F+R+T P G+V+F R+ LED +P W PL R V G IE+
Sbjct: 575 FRRVTEKKPTGLVTFTRQ--SLED------FPE---WERCEKPLTRLHVTYEGTIEENGQ 623
Query: 275 EAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSS 334
++VDFAN ++GGG G VQEEIRF+I+PELI+ LF + NE + I G E++S
Sbjct: 624 GMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNECLIITGTEQYSE 683
Query: 335 YTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREINKAFCG 393
YTGYA ++R+S ++ D + D RR T IVAIDAL + Q+ P+ + RE+NKA+CG
Sbjct: 684 YTGYAETYRWSRSHEDGSERDDWQRRCTEIVAIDALHFRRYLDQFVPEKMRRELNKAYCG 743
Query: 394 FLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRMEQCNNI 453
FL P +SE N
Sbjct: 744 FL---------------------------RPGVSSE---------------------NLS 755
Query: 454 GVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTF-RLEALHNIDKVAHWILSHR 512
VATGNWGCGAFGGD +K +IQ LAA+ A R + Y+TF E + +I + ++ +
Sbjct: 756 AVATGNWGCGAFGGDARLKALIQILAAAAAERD-VVYFTFGDSELMRDIYSMHIFLTERK 814
Query: 513 WTVGDLWNMLTEY 525
TVGD++ +L Y
Sbjct: 815 LTVGDVYKLLLRY 827
>gb|AAT66421.1| poly (ADP-ribose) glycohydrolase [Homo sapiens]
Length = 894
Score = 202 bits (514), Expect = 2e-50
Identities = 136/373 (36%), Positives = 192/373 (51%), Gaps = 62/373 (16%)
Query: 155 VFLSQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHY 214
+ +SQE IA+LL +FFC FP K S D F L++ S ++ K++ + Y
Sbjct: 541 ITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCY 600
Query: 215 FQRITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLS 274
F+R+T P G+V+F R+ LED +P W PL R V G IE+
Sbjct: 601 FRRVTEKKPTGLVTFTRQ--SLED------FPE---WERCEKPLTRLHVTYEGTIEENGQ 649
Query: 275 EAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSS 334
++VDFAN ++GGG G VQEEIRF+I+PELI+ LF + NE + I G E++S
Sbjct: 650 GMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNECLIITGTEQYSE 709
Query: 335 YTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREINKAFCG 393
YTGYA ++R+S ++ D + D RR T IVAIDAL + Q+ P+ + RE+NKA+CG
Sbjct: 710 YTGYAETYRWSRSHEDGSERDDWQRRCTEIVAIDALHFRRYLDQFVPEKMRRELNKAYCG 769
Query: 394 FLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRMEQCNNI 453
FL P +SE N
Sbjct: 770 FL---------------------------RPGVSSE---------------------NLS 781
Query: 454 GVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTF-RLEALHNIDKVAHWILSHR 512
VATGNWGCGAFGGD +K +IQ LAA+ A R + Y+TF E + +I + ++ +
Sbjct: 782 AVATGNWGCGAFGGDARLKALIQILAAAAAERD-VVYFTFGDSELMRDIYSMHIFLTERK 840
Query: 513 WTVGDLWNMLTEY 525
TVGD++ +L Y
Sbjct: 841 LTVGDVYKLLLRY 853
>emb|CAH90218.1| hypothetical protein [Pongo pygmaeus]
Length = 978
Score = 202 bits (514), Expect = 2e-50
Identities = 136/373 (36%), Positives = 193/373 (51%), Gaps = 62/373 (16%)
Query: 155 VFLSQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHY 214
+ +SQE IA+LL +FFC FP K S D F L++ S ++ K++ + Y
Sbjct: 625 ITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCY 684
Query: 215 FQRITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLS 274
F+R+T P G+V+F R+ LED +P W PL R V G IE+
Sbjct: 685 FRRVTEKKPTGLVTFTRQ--SLED------FPE---WERCEKPLTRLHVTYEGTIEENGR 733
Query: 275 EAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSS 334
++VDFAN ++GGG G VQEEIRF+I+PELI+ LF + NE + I G E++S
Sbjct: 734 GMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNECLIITGTEQYSE 793
Query: 335 YTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREINKAFCG 393
YTGYA ++R+S ++ D + D RR T IVAIDAL + Q+ P+ + RE+NKA+CG
Sbjct: 794 YTGYAETYRWSRSHEDGSERDGWQRRCTEIVAIDALHFRRYLDQFVPEKMRRELNKAYCG 853
Query: 394 FLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRMEQCNNI 453
FL P +SE N
Sbjct: 854 FL---------------------------RPGVSSE---------------------NLS 865
Query: 454 GVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTF-RLEALHNIDKVAHWILSHR 512
VATGNWGCGAFGGD +K +IQ LAA+ A R + Y+TF E + +I + ++ +
Sbjct: 866 AVATGNWGCGAFGGDARLKALIQILAAAAAERD-VVYFTFGDSELMRDIYSMHIFLTERK 924
Query: 513 WTVGDLWNMLTEY 525
TVGD++ +L +Y
Sbjct: 925 LTVGDVYKLLLQY 937
>gb|AAH52966.1| PARG protein [Homo sapiens]
Length = 976
Score = 200 bits (509), Expect = 9e-50
Identities = 135/373 (36%), Positives = 191/373 (51%), Gaps = 62/373 (16%)
Query: 155 VFLSQELIAALLVCSFFCLFPVNERYGKHLQSINFDELFGSLYDYYSQKQESKIQCIIHY 214
+ +SQE IA+LL +FFC FP K S D F L++ S ++ K++ + Y
Sbjct: 623 ITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCY 682
Query: 215 FQRITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLS 274
F+R+T P G+V+F R+ LED +P W PL R V G IE+
Sbjct: 683 FRRVTEKKPTGLVTFTRQ--SLED------FPE---WERCEKPLTRLHVTYEGTIEENGQ 731
Query: 275 EAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSS 334
++VDFAN ++GGG G VQEEIRF+I+PELI+ LF + NE + I G E++S
Sbjct: 732 GMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNECLIITGTEQYSE 791
Query: 335 YTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREINKAFCG 393
YTGYA ++R+S ++ D + D R T IVAIDAL + Q+ P+ + RE+NKA+CG
Sbjct: 792 YTGYAETYRWSRSHEDGSERDDWQRHCTEIVAIDALHFRRYLDQFVPEKMRRELNKAYCG 851
Query: 394 FLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRMEQCNNI 453
FL P +SE N
Sbjct: 852 FL---------------------------RPGVSSE---------------------NLS 863
Query: 454 GVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTF-RLEALHNIDKVAHWILSHR 512
VATGNWGCGAFGGD +K +IQ LAA+ A R + Y+TF E + +I + ++ +
Sbjct: 864 AVATGNWGCGAFGGDARLKALIQILAAAAAERD-VVYFTFGDSELMRDIYSMHIFLTERK 922
Query: 513 WTVGDLWNMLTEY 525
TVGD++ +L Y
Sbjct: 923 LTVGDVYKLLLRY 935
>ref|XP_642024.1| hypothetical protein DDB0204317 [Dictyostelium discoideum]
gi|60470164|gb|EAL68144.1| hypothetical protein
DDB0204317 [Dictyostelium discoideum]
Length = 658
Score = 200 bits (509), Expect = 9e-50
Identities = 143/451 (31%), Positives = 206/451 (44%), Gaps = 100/451 (22%)
Query: 96 TIEESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRTGLRLLDSQEPGIV 155
T E+ ++F + +P + L L+LP L + LL S +
Sbjct: 265 TESETNEFFSQTLPKIIKLALQLPFLCARP------------------IPLLKSSVDREI 306
Query: 156 FLSQELIAALLVCSFFCLFPV--------NERYGKHLQ---------SINFDELFGSLYD 198
LSQ+ +++LL +F C FP N H + SINF LF
Sbjct: 307 ILSQKQVSSLLANAFLCTFPRQGNITSNNNNNNNNHYRRGGNQDKFPSINFHSLFSGKM- 365
Query: 199 YYSQKQESKIQCIIHYFQRITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPL 258
+ +K++CI HYF+ +T P G +SF R+V + P+ W S L
Sbjct: 366 --IPSRAAKLKCIFHYFKCVTEKTPTGTISFHRQVFDESE------IPD---WERSTATL 414
Query: 259 CRFEVHSSGLIEDQLSEAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSM 318
+ G IED ++ DFAN+ LGGG L GCVQEEIRF+I+PEL+V LF +
Sbjct: 415 RDLTCFTEGTIEDNGIGMLQADFANKSLGGGVLGYGCVQEEIRFVINPELLVSCLFTSIL 474
Query: 319 ADNEAIEIVGVERFSSYTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDALCSP----G 374
+NE + I G +RFS YTGY SF+++G Y+D+ D +GRR T IVA+DA+ P
Sbjct: 475 QENETVIITGSQRFSKYTGYGDSFQWNGPYIDKTPYDQMGRRLTSIVAMDAIKLPHGGNS 534
Query: 375 MRQYRPKFLLREINKAFCGFLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSN 434
+Q+ P + RE+NK+ CGF FD + T
Sbjct: 535 FQQFSPSAVERELNKSLCGF----------------------FDRVSLTIPPP------- 565
Query: 435 HEIRDSQNDYHRMEQCNNIGVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFR 494
VATGNWGCG FGGD +K+IIQ ++ SQA R + +
Sbjct: 566 --------------------VATGNWGCGVFGGDKHLKSIIQLMSGSQAGRDLVYFSFGD 605
Query: 495 LEALHNIDKVAHWILSHRWTVGDLWNMLTEY 525
E + ++ ++ + TVG L+ L EY
Sbjct: 606 QEFTDELTQMISFLHLKKVTVGGLYKALWEY 636
>emb|CAG05369.1| unnamed protein product [Tetraodon nigroviridis]
Length = 327
Score = 197 bits (502), Expect = 6e-49
Identities = 132/384 (34%), Positives = 194/384 (50%), Gaps = 70/384 (18%)
Query: 143 GLRLLDSQEPGIVFLSQELIAALLVCSFFCLFPVNERYGKHLQ-----SINFDELFGSLY 197
G+ LL + LSQ I+ LL +FFC FP H SINF LF
Sbjct: 5 GIPLLQQGRAAAITLSQAQISCLLANAFFCTFPHRNSTSFHSDYHTYPSINFTRLFS--- 61
Query: 198 DYYSQKQESKIQCIIHYFQRITSNMPQ--GVVSFERKVLPLEDDYIHISYPNADVWSTSI 255
++S+++ K++ I+HYF T + G+V+FER+ L D A WS
Sbjct: 62 -HWSERKMEKLKAIVHYFHVATDEKTKLDGLVTFERRCLANTD---------ARTWSCCK 111
Query: 256 IPLCRFEVHSSGLIEDQLSEAVEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFL 315
+ + V S G IE + S ++VDFA+ +LGGG L G +QEEI F++SPELIV LF
Sbjct: 112 EEMNKLYVSSCGAIETEGSGLLQVDFASSWLGGGVLDSGLLQEEILFLMSPELIVSRLFT 171
Query: 316 PSMADNEAIEIVGVERFSSYTGYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPG 374
+ DNE + + G ++FS+Y+GY +FR+ G Y D D RR+ +++A+DAL + G
Sbjct: 172 EKLQDNECVIVTGCQQFSTYSGYGDTFRWKGPYADPTGRDGWARRQRQVLAMDALRFTHG 231
Query: 375 MRQYRPKFLLREINKAFCGFLYGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSN 434
QY K ++RE+NKA+CGF K
Sbjct: 232 RDQYSMKLVVRELNKAYCGF------------------------------------KRCE 255
Query: 435 HEIRDSQNDYHRMEQCNNIGVATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFR 494
E R + D +ATG WGCGAF GDP++K +IQ +AA++A R +A++TF+
Sbjct: 256 EERRGEEPD-----------IATGKWGCGAFKGDPQLKAVIQLMAAARAGRG-LAFFTFK 303
Query: 495 LEAL-HNIDKVAHWILSHRWTVGD 517
E L H + + + + TVG+
Sbjct: 304 DEKLEHGLRQAYRLLRTKGTTVGE 327
>emb|CAF98668.1| unnamed protein product [Tetraodon nigroviridis]
Length = 463
Score = 196 bits (498), Expect = 2e-48
Identities = 136/399 (34%), Positives = 200/399 (50%), Gaps = 77/399 (19%)
Query: 99 ESRKWFQEVVPALGILLLRLPSLLEAHYQNADRVLDEDGGLVRT-GLRLLDSQEPGIVFL 157
E + +F+ V+PA+ L ++ P L ++R + LL ++ + L
Sbjct: 33 EKQHFFEVVLPAMVELAVQAPFLCTM------------ASILRIFPIPLLKARMNHSLTL 80
Query: 158 SQELIAALLVCSFFCLFPVNERYGKHLQSINFDEL-FGSLYDYYSQKQESKIQCIIHYFQ 216
SQE IA LL +FFC FP R + + N+ E+ F L++ S ++ K++ ++ YF+
Sbjct: 81 SQEQIACLLANAFFCTFP--RRNSRKSEYGNYPEINFYRLFEGSSMRKIEKLKTLLCYFR 138
Query: 217 RITSNMPQGVVSFERKVLPLEDDYIHISYPNADVWSTSIIPLCRFEVHSSGLIEDQLSEA 276
R+T N P+G+V+F R+ L W +S L R + G IED
Sbjct: 139 RVTQNRPKGLVTFTRQTLN-----------EPPKWESSQKQLTRLHITCQGTIEDDGYGM 187
Query: 277 VEVDFANEYLGGGALRRGCVQEEIRFMISPELIVDMLFLPSMADNEAIEIVGVERFSSYT 336
++VDFAN ++GGG G VQEEIRF+I+PELIV LF ++ +E + I G ER+S Y+
Sbjct: 188 LQVDFANRFVGGGVTGHGLVQEEIRFLINPELIVSRLFTEALEHDECLIITGTERYSKYS 247
Query: 337 GYASSFRFSGNYVDERDVDTLGRRKTRIVAIDAL-CSPGMRQYRPKFLLREINKAFCGFL 395
GYA S+++ ++DE D RR T IVAIDAL + Q+ P+ + RE+ KA+CGF
Sbjct: 248 GYAESYKWQDCHIDETPSDEWQRRCTEIVAIDALKFRHYLEQFVPQKIRRELYKAYCGFF 307
Query: 396 YGSKHQLYQKILQEKGCPSTLFDAATSTPMETSEGKCSNHEIRDSQNDYHRMEQCNNIGV 455
C S A V
Sbjct: 308 -------------RNNCESKHLSA-----------------------------------V 319
Query: 456 ATGNWGCGAFGGDPEVKTIIQWLAASQALRPFIAYYTFR 494
ATGNWGCGAFGGD +K +IQ +AA++A R +AY+TFR
Sbjct: 320 ATGNWGCGAFGGDTRLKALIQLMAAAEAGRD-VAYFTFR 357
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.321 0.138 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 998,906,856
Number of Sequences: 2540612
Number of extensions: 43873926
Number of successful extensions: 107754
Number of sequences better than 10.0: 80
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 107546
Number of HSP's gapped (non-prelim): 128
length of query: 558
length of database: 863,360,394
effective HSP length: 133
effective length of query: 425
effective length of database: 525,458,998
effective search space: 223320074150
effective search space used: 223320074150
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 78 (34.7 bits)
Lotus: description of TM0057b.8