hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg00138/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4230  ( 408 res)   mbg00138

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       362.1     6e-105   1
Pkinase_Tyr Protein tyrosine kinase                     124.0    2.7e-33   1
UBA         UBA/TS-N domain                              26.1    0.00082   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase_Tyr   1/1      64   313 ..     1   272 []   124.0  2.7e-33
Pkinase       1/1      64   315 ..     1   287 []   362.1   6e-105
UBA           1/1     335   374 ..     1    45 []    26.1  0.00082

Alignments of top-scoring domains:
Pkinase_Tyr: domain 1 of 1, from 64 to 313: score 124.0, E = 2.7e-33
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtL.keigasseei
                       +l+k++G+G+F +V +++       t+ +VA+K+++k     +   
   mKIAA4230    64    YRLLKTIGKGNFAKVKLARHI----LTGREVAIKIIdKT-QLNPTS- 104  

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                    +++++rE++iMk l +HpNiV+L  v+   ++     ly+++Ey+ gG 
   mKIAA4230   105 -LQKLFREVRIMKIL-NHPNIVKLFEVIET-EKT----LYLIMEYASGGE 147  

                   LldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLV
                     d+L +h   ++ + k+     +Qi ++ +Y ++k++vHRDL A N L+
   mKIAA4230   148 VFDYLVAH---GRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLL 194  

                   senlvVKIsDFGLaRdiynddyYvrkkgggk.l..PvkWmAPEslkygkF
                   + ++ +KI+DFG +          +++++  ++ +     APE ++ +k+
   mKIAA4230   195 DADMNIKIADFGFSNEF-------TVGSKLDtFcgSPPYAAPELFQGKKY 237  

                   .tskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPen
                   +  + DVWS GV L+ +++ G  P + g    e+ e++ +  yR p  + 
   mKIAA4230   238 dGPEVDVWSLGVILYTLVS-GSLP-FDGQNLKELRERVLRGKYRIPFYM- 284  

                   CPdelYdlMlqCWaedPedRPtFselverL<-*
                    + +  +l ++    +P +R t +++  +    
   mKIAA4230   285 -STDCENLLKRFLVLNPVKRGTLEQIMKDR    313  

Pkinase: domain 1 of 1, from 64 to 315: score 362.1, E = 6e-105
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      y+ll+++G+G+f++V++a+h+ tg++VA+Kii+k   ++  ++ ++r
   mKIAA4230    64    YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFR 110  

                   rsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrlldLfdylse
                     E++i+k L+HpNIv+l++v e+++ lyl++Ey+ gG    + fdyl  
   mKIAA4230   111 --EVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGG----EVFDYLV- 153  

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldengv
                     ++g++   e+ea+  ++Qi+++++Y+H+++i+HRDLK eN+Lld +++
   mKIAA4230   154 --AHGRM--KEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMN 199  

                   vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD
                   +    KiaDFG++     + +s+l+tf+G+p+Y+APE+ +g +++g++vD
   mKIAA4230   200 I----KIADFGFSNE--FtVGSkLDTFCGSPPYAAPELFQGKKYDGPEVD 243  

                   vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi
                   vWSlGvily l++G +PF+g+     + ++l +++l+++++++++ +   
   mKIAA4230   244 VWSLGVILYTLVSGSLPFDGQ-----NLKELRERVLRGKYRIPFYMS--- 285  

                   srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                                ++  L+k+ L ++P kR t e+i+++ w+   
   mKIAA4230   286 ------------TDCENLLKRFLVLNPVKRGTLEQIMKDRWI    315  

UBA: domain 1 of 1, from 335 to 374: score 26.1, E = 0.00082
                   *->ideelvkqLreMGGGvfsreeakkALratnnnsDverAvewLleh<-
                      +d++ ++ ++ MG   +s+ee+ + L +  +  D+ +A+++Ll +  
   mKIAA4230   335    SDQKRIDIMVGMG---YSQEEIQESLSKMKY--DEITATYLLLGR   374  

                   *
                    
   mKIAA4230     -   -    

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