hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj58259/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4225  ( 868 res)   mfj58259

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
Sema     Sema domain                                    744.2   5.5e-220   1
PSI      Plexin repeat                                   52.5    9.4e-12   1
ig       Immunoglobulin domain                           20.7      0.036   1
V-set    Immunoglobulin V-set domain                     11.4      0.044   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Sema       1/1      57   489 ..     1   490 []   744.2 5.5e-220
PSI        1/1     509   561 ..     1    63 []    52.5  9.4e-12
ig         1/1     576   633 ..     1    65 []    20.7    0.036
V-set      1/1     536   654 ..     1   130 []    11.4    0.044

Alignments of top-scoring domains:
Sema: domain 1 of 1, from 57 to 489: score 744.2, E = 5.5e-220
                   *->frtllldedrgrLyVGArNhvyvLnledlserlqqkigWpsspgeek
                      +++ll++ed+++LyVGAr++v+++n  ++se  q++++W++s  e+k
   mKIAA4225    57    YSALLMSEDKDTLYVGAREAVFAVNALNISEK-QHEVYWKVS--EDK 100  

                   ceeCkmkgkspgcVeteCqNfirVLqpyndthLyvCGTnaFqPvCtlinl
                   +++C+ kgks+   +teC N+irVLqp ++t LyvCGTnaFqP+C ++nl
   mKIAA4225   101 KSKCAEKGKSK---QTECLNYIRVLQPLSSTSLYVCGTNAFQPTCDHLNL 147  

                   gdrseaviiaetdcLFsldvekeesGkgrCPydPlhnstsvlvqgrtgeL
                   ++             F++  +k+e+GkgrCP+dP+h++tsv+v g  geL
   mKIAA4225   148 TS-------------FKF-LGKSEDGKGRCPFDPAHSYTSVMV-G--GEL 180  

                   YsGtviDssvaasFsGrdpaIrRslgshdplrTeqhdskwlnePnFVdsy
                   YsGt+++      F+G++p+I R   sh+plrTe+    wlneP+FV ++
   mKIAA4225   181 YSGTSYN------FLGSEPIISRNS-SHSPLRTEY-AIPWLNEPSFVFAD 222  

                   pipyvhsf...dDdkVYFFFrEtaveyspnsgkaiysRVaRvCknDvGGr
                   +i+++++ ++++DdkVYFFF+E +vey+ +++k++++RVaRvCk+D+GG 
   mKIAA4225   223 VIQKSPDGpegEDDKVYFFFTEVSVEYE-FVFKLMIPRVARVCKGDQGGL 271  

                   rylelnkWTTFLKARLnCSvpGeegipkfyFNeLQavfllptganlAreL
                   r+l+ +kWT+FLKARL+CS p+  +    +FN+LQ+vf+l++++      
   mKIAA4225   272 RTLQ-KKWTSFLKARLICSKPD--S-G-LVFNILQDVFVLRAPGL----- 311  

                   gIserdpviYGVFttssnsiagpgdnSAVCaFsmsdIrqvFenGpfkhqs
                       ++pv+Y+VFt + n ++     SAVCa++++++++vF+ G++++ +
   mKIAA4225   312 ----KEPVFYAVFTPQLNNVGL----SAVCAYTLATVEAVFSRGKYMQSA 353  

                   n.EgpnskwlpyrglkvPyPRPGqCpndssgp.nytStkdlPDdtlnfik
                   + E++++kw++y+g +vP+PRPG C+ +  ++ nytS+++lPD+tl+f+k
   mKIAA4225   354 TvEQSHTKWVRYNG-PVPTPRPGACIDSEARAaNYTSSLNLPDKTLQFVK 402  

                   shpLmdevvpPlhnrPlfvgtsvnyrlTqIaVdkrVragdGqlYtVlFlG
                   +hpLmd++v+P+ nrP +++++vny  TqI+Vd r +a+dG++Y+V+F++
   mKIAA4225   403 DHPLMDDSVTPIDNRPKLIKKDVNY--TQIVVD-RTQALDGTFYDVMFIS 449  

                   TddGtvlKkvvvlsrsss.syeevvleelqvfkdpriePvqnleisskq<
                   Td+G ++ k+v+l   ++ +    v+ee+q+f+d+  ePv++l++ssk+ 
   mKIAA4225   450 TDRGALH-KAVIL--TKEvH----VIEETQLFRDS--EPVLTLLLSSKK  489  

                   -*
                     
   mKIAA4225     -    -    

PSI: domain 1 of 1, from 509 to 561: score 52.5, E = 9.4e-12
                   *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfyGeCpraep
                       C+ ++sC +C++ardp yC+W +  + C++ +++      ++r++ 
   mKIAA4225   509    FCEKHGSCEDCVLARDP-YCAWSPAIKACVTLHQE----EASSRGW- 549  

                   endqwldwswssskCp<-*
                       ++d+s ++s C    
   mKIAA4225   550 ----IQDMSGDTSSCL    561  

ig: domain 1 of 1, from 576 to 633: score 20.7, E = 0.036
                   *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq
                      G+++ L C      +  ++v W++++++l    + + ++ +      
   mKIAA4225   576    GGTAELKCFQ---KSNLARVVWKFQNGeLKaASPKYGFVGRKH---- 615  

                   tsLtitnvtpeDggtYtCvv<-*
                     L i n++ +D+g+Y C     
   mKIAA4225   616 --LLIFNLSDGDSGVYQCLS    633  

V-set: domain 1 of 1, from 536 to 654: score 11.4, E = 0.044
                   *->qstvtqepprLLLASLfWp.t........................sv
                      ++t++q  ++        +++++  ++ ++++++  ++++++ +++ 
   mKIAA4225   536    CVTLHQ--EE--------AsSrgwiqdmsgdtsscldkskesfnqH- 571  

                   tvaeGgsvtLpCtysGtfddsssssgtgsvyWyrqqppGekpeliiisyy
                   + + Gg+++L+C+++     s    +  +v W + q+             
   mKIAA4225   572 FFKHGGTAELKCFQK-----S----NLARVVWKF-QNG------------ 599  

                   tyysysegngtvserfkgrvrfsgnpskgdfsLtIsnlqlsDsGtYyCa.
                      +       ++  f gr +           L I nl+  DsG+Y C +
   mKIAA4225   600 -ELKAA----SPKYGFVGRKH-----------LLIFNLSDGDSGVYQCLs 633  

                   ............gggtrLtVl<-*
                   +++ ++++ +      +L V+   
   mKIAA4225   634 eervrnktvsqlLAKHVLEVK    654  

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