hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg07317/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4223  ( 1076 res)   mbg07317

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PDZ      PDZ domain (Also known as DHR or GLGF)         341.6    8.6e-99   7

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PDZ        1/7      69   149 ..     1    82 []    45.6  1.1e-09
PDZ        2/7     168   251 ..     1    82 []    68.7  1.2e-16
PDZ        3/7     268   349 ..     1    82 []    37.9  2.3e-07
PDZ        4/7     435   521 ..     1    82 []    47.9  2.3e-10
PDZ        5/7     536   618 ..     1    82 []    51.2  2.2e-11
PDZ        6/7     636   715 ..     1    82 []    68.1  1.9e-16
PDZ        7/7     952  1031 ..     1    82 []    30.8  3.2e-05

Alignments of top-scoring domains:
PDZ: domain 1 of 7, from 69 to 149: score 45.6, E = 1.1e-09
                   *->evtlekevkrgglGfsikggsdk..givvsevlpGsgaAeagGrLke
                       v l+k  ++  lG++++gg dk++   vs++ +G g A+++  L +
   mKIAA4223    69    VVELMKK-EGTTLGLTVSGGIDKdgKPRVSNLRQG-GIAARSDQLDV 113  

                   GDqIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                   GD I +vNG ++++++h++++ +lk+ g+  v L+++   
   mKIAA4223   114 GDYIKAVNGINLAKFRHDEIISLLKNVGE-RVVLEVE    149  

PDZ: domain 2 of 7, from 168 to 251: score 68.7, E = 1.2e-16
                   *->evtlekevkrgglGfsikggsdk......givvsevlpGsgaAeagG
                      evtl+k  +++ +Gf i+gg  +++++++++v++ v pG g+A++ G
   mKIAA4223   168    EVTLHK--EGNTFGFVIRGGAHDdrnksrPVVITCVRPG-GPADREG 211  

                   rLkeGDqIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                    +k+GD++lsv+G  + + +h++a+ +lk++g+ e tL+i+   
   mKIAA4223   212 TIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQ-EATLLIE    251  

PDZ: domain 3 of 7, from 268 to 349: score 37.9, E = 2.3e-07
                   *->evtlekevkrgglGfsikggsdk...givvsevlpGsgaAeagGrLk
                      +v + k   + +lG+ +     ++++ iv+ ++    + A++ G+L+
   mKIAA4223   268    LVEVAKT-PGASLGVALTTSVCCnkqVIVIDKIKSA-SIADRCGALH 312  

                   eGDqIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                   +GD Ils++G+++e  ++++a ++l ++ + +v+L+il   
   mKIAA4223   313 VGDHILSIDGTSMEYCTLAEATQFLANTTD-QVKLEIL    349  

PDZ: domain 4 of 7, from 435 to 521: score 47.9, E = 2.3e-10
                   *->evtlekevkrgglGfsikggsdk......givvsevlpGsgaAeagG
                      ev+l  +    g+G++++g   ++++ +++  +s + ++ ++Ae+ G
   mKIAA4223   435    EVVLTAD-PVTGFGIQLQGSVFAtetlssPPLISYIEAD-SPAERCG 479  

                   rLkeGDqIlsvNGqdvenlsheravlalkgsgg.sevtLtil<-*
                    L++GD+++++NG ++e+ + e+a ++l++s+ +s+vtL+i+   
   mKIAA4223   480 VLQIGDRVMAINGIPTEDSTFEEANQLLRDSSItSKVTLEIE    521  

PDZ: domain 5 of 7, from 536 to 618: score 51.2, E = 2.2e-11
                   *->evtlekevkrgglGfsikggsdk....givvsevlpGsgaAeagGrL
                       v+l+k      lG++i++ s+ ++++++v+s++ +G + A++ G L
   mKIAA4223   536    HVKLPKK-HSVELGITISSPSSRkpgdPLVISDIKKG-SVAHRTGTL 580  

                   keGDqIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                   + GD++l++++  + n s e+av++l+++ +  v+L+i+   
   mKIAA4223   581 ELGDKLLAIDNIRLDNCSMEDAVQILQQCED-LVKLKIR    618  

PDZ: domain 6 of 7, from 636 to 715: score 68.1, E = 1.9e-16
                   *->evtlekevkrgglGfsikggsdk..givvsevlpGsgaAeagGrLke
                      +v l++   +g+lG++i+g ++  ++i++s++ +G g Ae+ G++++
   mKIAA4223   636    TVELKR--YGGPLGITISGTEEPfdPIIISSLTKG-GLAERTGAIHI 679  

                   GDqIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                   GD+Il++N  ++ + ++ +a+ +l+++g+ +vtL+i+   
   mKIAA4223   680 GDRILAINSSSLKGKPLSEAIHLLQMAGE-TVTLKIK    715  

PDZ: domain 7 of 7, from 952 to 1031: score 30.8, E = 3.2e-05
                   *->evtlekevkrgglGfsikggsdk.givvsevlpGsgaAeagGrLkeG
                      +vtl k+ + + +Gfs++ g  ++g++v+++ p  g+ ++gG Lk+ 
   mKIAA4223   952    KVTLYKDSGMEDFGFSVADGLLEkGVYVKNIRPA-GPGDVGG-LKPY 996  

                   DqIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                   D++l+vN + ++++    +v ++ +sg+ ++ L+i    
   mKIAA4223   997 DRLLQVNHVRTRDFDCCLVVPLIAESGN-KLDLVIS    1031 

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