hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg08227/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4212  ( 600 res)   mbg08227

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RUN      RUN domain                                     141.6    1.4e-38   1
FYVE     FYVE zinc finger                               110.3    3.6e-29   1
Filament Intermediate filament protein                 -186.7       0.47   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RUN        1/1      39   163 ..     1   174 []   141.6  1.4e-38
Filament   1/1     216   501 ..     1   359 []  -186.7     0.47
FYVE       1/1     529   593 ..     1    77 []   110.3  3.6e-29

Alignments of top-scoring domains:
RUN: domain 1 of 1, from 39 to 163: score 141.6, E = 1.4e-38
                   *->tLCpaleAllsHGLkrpelltgaihpwafiedaaagefekaalsvls
                      +++ ++e++l+HGLk                          + s++ 
   mKIAA4212    39    QFFVVMEHCLKHGLK-------------------------VKKSFIG 60   

                   sssllldsqrslgcdtnnldpsfkvlpvaeslkhivsqieqLaeKrSsvi
                   +       ++s+      ++p+++v ++ ++  +i  ++++L+e     +
   mKIAA4212    61 Q-------NKSF------FGPLELVEKLCPEASDIATSVRNLPE-----L 92   

                   ktavgrgRKyAWiRlaLneksLssylklLlsdeellrkyYkpnAlLrdpS
                   ktavgrgR  AW++laL++k+L  ylk L++++ ll+++Y+p+Al+++  
   mKIAA4212    93 KTAVGRGR--AWLYLALMQKKLADYLKVLIDNKQLLSEFYEPEALMME-- 138  

                   deegCeillslLqgLsaldFsLdlkfe<-*
                    eeg   + +lL+gL++ld +L+lk+e   
   mKIAA4212   139 -EEG-MVIVGLLVGLNVLDANLCLKGE    163  

Filament: domain 1 of 1, from 216 to 501: score -186.7, E = 0.47
                   *->nEKeqmQnLNDRLAsYIdKVRfLEqqNkeLevkieelrqkqsrggpa
                          ++Q+          K++ LE+ N++L+ ++++  ++ +     
   mKIAA4212   216    ----DLQT----------KIDGLEKTNSKLQEELSAATDRIC----- 243  

                   svsrlyslYeteieeLRrqidqltner...........arlqlE.....i
                   s+       ++e ++LR+q +++ +er++++ + ++++ +++lE+ ++++
   mKIAA4212   244 SL-------QKEQQQLREQ-NEVIRERseksveitkqdTKVELEtykqtR 285  

                   dnlrealedfrkKyedKeDLaaQnqlkdlEialntkeaeLaTaLeRqeaE
                     l e + d+ k++++             E               R e+E
   mKIAA4212   286 QGLDEMYSDVWKQLKE-------------EKKV------------RLELE 310  

                   ndlvgLRaQiAklEslaaRkdlDeaTLarvDLEnkvEsLqEElaFLKknH
                    +l+ +             +  + +  +++ LE+     q+ l  L++  
   mKIAA4212   311 KELELQ-----------IGMKTEMEIAMKL-LEKDTHEKQDTLVALRQQL 348  

                   eEEvkeLqaqiqdtg.......qvnVEmDaarqqEwklDLtkaLrEiRaQ
                    EEvk +  q  ++ ++ +++ q + E  a++    + + t+++  +++ 
   mKIAA4212   349 -EEVKAINLQMFHKVqsaesslQQKNEAIASF----EGKTTQVMSSMKQM 393  

                   YE..eiAeknrqeaEewYksKleeLqtaaarngealrsaKeEitElRRqi
                    E+ ++Ae+ rq aEe    ++  Lq++ +  g al+ +   +++lR q 
   mKIAA4212   394 EErlQQAERARQAAEE----RSHKLQQELSGRGSALQLQ---LSQLRDQC 436  

                   QsLeiELqslksqnasLErqlaElEeryeaelaqyqalisqlEeeLqqlr
                     Le EL s k q+++L+r+l+  +++ ++ + ++q +   l  eL++l 
   mKIAA4212   437 SGLEKELKSEKEQRQALQRELQREKDTSCLLQTELQ-QVEGLKKELRELQ 485  

                   eEMarqLrEYQeLLdVKlaLDiEIATYRKLLEGEEsR<-*
                   +E a +                     RK  E +E+    
   mKIAA4212   486 DEKAEL---------------------RKVCEEQEQA    501  

FYVE: domain 1 of 1, from 529 to 593: score 110.3, E = 3.6e-29
                   *->phWvpDeevsnCmrCgkpFtkltkRrHHCRaCGrifCgsCssktvll
                      ++W++D+e+++C +C+k F+ + +R+HHCR+CG+ifC++Css++++l
   mKIAA4212   529    HTWLKDDEATHCKQCEKDFS-ISRRKHHCRNCGHIFCNTCSSNELAL 574  

                   pylgiaallkndviekpvRVCdsCydrlnk<-*
                   p+             kpvRVCdsC+++l +   
   mKIAA4212   575 PSY-----------PKPVRVCDSCHTLLLQ    593  

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