hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mph/mph00550/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4207  ( 780 res)   mph00550

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       363.7     2e-105   1
Pkinase_Tyr Protein tyrosine kinase                     128.0    1.8e-34   1
KA1         Kinase associated domain 1                   86.1      7e-22   1
UBA         UBA/TS-N domain                              20.8      0.032   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase_Tyr   1/1      57   306 ..     1   272 []   128.0  1.8e-34
Pkinase       1/1      57   308 ..     1   287 []   363.7   2e-105
UBA           1/1     328   367 ..     1    45 []    20.8    0.032
KA1           1/1     731   780 .]     1    50 []    86.1    7e-22

Alignments of top-scoring domains:
Pkinase_Tyr: domain 1 of 1, from 57 to 306: score 128.0, E = 1.8e-34
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtL.keigasseei
                       +l+k++G+G+F +V +++       t+ +VAVK+++k     s+  
   mKIAA4207    57    YRLLKTIGKGNFAKVKLARHI----LTGKEVAVKIIdKT-QLNSSS- 97   

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                    +++++rE++iMk l +HpNiV+L  v+   ++     ly+V+Ey+ gG 
   mKIAA4207    98 -LQKLFREVRIMKVL-NHPNIVKLFEVIET-EKT----LYLVMEYASGGE 140  

                   LldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLV
                     d+L +h   ++ + k+     +Qi ++ +Y ++k +vHRDL A N L+
   mKIAA4207   141 VFDYLVAH---GRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL 187  

                   senlvVKIsDFGLaRdiynddyYvrkkgggk.lPvkWmAPEslkygkF.t
                   + ++ +KI+DFG +         +  k ++        APE ++ +k++ 
   mKIAA4207   188 DADMNIKIADFGFSNEF-----TFGNKLDTFcGSPPYAAPELFQGKKYdG 232  

                   skSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPenCP
                    + DVWS GV L+ +++ G  P + g    e+ e++ +  yR p  +  +
   mKIAA4207   233 PEVDVWSLGVILYTLVS-GSLP-FDGQNLKELRERVLRGKYRIPFYM--S 278  

                   delYdlMlqCWaedPedRPtFselverL<-*
                    +  +l ++    +P++R t +++  +    
   mKIAA4207   279 TDCENLLKKFLILNPSKRGTLEQIMKDR    306  

Pkinase: domain 1 of 1, from 57 to 308: score 363.7, E = 2e-105
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      y+ll+++G+G+f++V++a+h+ tgk+VAvKii+k   +s+ ++ ++r
   mKIAA4207    57    YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFR 103  

                   rsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrlldLfdylse
                     E++i+k L+HpNIv+l++v e+++ lylV+Ey+ gG    + fdyl  
   mKIAA4207   104 --EVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGG----EVFDYLV- 146  

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldengv
                     ++g++   e+ea+  ++Qi+++++Y+H++ i+HRDLK eN+Lld +++
   mKIAA4207   147 --AHGRM--KEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMN 192  

                   vdaflKiaDFGlAkklst.ssslttfvGTpwYmAPEvllggngygtkvDv
                   +    KiaDFG++  + t  + l+tf+G+p+Y+APE+ +g +++g++vDv
   mKIAA4207   193 I----KIADFGFSNEF-TfGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV 237  

                   WSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsis
                   WSlGvily l++G +PF+g+     + ++l +++l+++++++++ +    
   mKIAA4207   238 WSLGVILYTLVSGSLPFDGQ-----NLKELRERVLRGKYRIPFYMS---- 278  

                   rsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                               ++  L+kk L ++PskR t e+i+++ w+   
   mKIAA4207   279 -----------TDCENLLKKFLILNPSKRGTLEQIMKDRWM    308  

UBA: domain 1 of 1, from 328 to 367: score 20.8, E = 0.032
                   *->ideelvkqLreMGGGvfsreeakkALratnnnsDverAvewLleh<-
                       d+   + +++MG   ++ree+ + L    +n  + +A+++Ll    
   mKIAA4207   328    KDPRRTELMVSMG---YTREEIQDSLVGQRYN--EVMATYLLLGY   367  

                   *
                    
   mKIAA4207     -   -    

KA1: domain 1 of 1, from 731 to 780: score 86.1, E = 7e-22
                   *->ddksksvvkFEiqlyKlprldlyGvdfqRisGpqwlFkdLcsailne
                      ++   + v++E++++Klprl+l+Gv+f+RisG++ +Fk+++s+i+ne
   mKIAA4207   731    TPGHENFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANE 777  

                   Lkv<-*
                   Lk+   
   mKIAA4207   778 LKL    780  

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