hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbj/mbj00115/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA4172  ( 515 res)   mbj00115

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N 
--------     -----------                                -----    ------- ---
Sulfatase    Sulfatase                                  276.6    3.1e-79   1
Phosphodiest Type I phosphodiesterase / nucleotide py   -98.0       0.68   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
Phosphodiest   1/1      29   412 ..     1   460 []   -98.0     0.68
Sulfatase      1/1      28   448 ..     1   531 []   276.6  3.1e-79

Alignments of top-scoring domains:
Phosphodiest: domain 1 of 1, from 29 to 412: score -98.0, E = 0.68
                   *->pkllvislDGfradyldrlyha.gltPnlsaLlaeeGvsapytltpv
                      p  l+i  D ++ + l  ++h++ +tPnl++L ae G +     t  
   mKIAA4172    29    PNILLIFADDLGYGDLGSYGHPsSTTPNLDQL-AEGGLR----FTDF 70   

                   fPtlTf..PnhytlvTGlyPesHGIvgNtfyDpktgavvyffeltdseav
                   + +++  +P+ + l+TG+ P + G++      p+   +        s++ 
   mKIAA4172    71 YVPVSLctPSRAALLTGRLPVRSGMY------PGVLGP--------SSQG 106  

                   ldpknWWdtttdglslkdnggepiwvtaqkqGgaiaaagvkaaaffWPgs
                     p+                  ++ +++++ G    + g+ +  ++  g 
   mKIAA4172   107 GLPL---------------EEVTLAEVLAARG---YLTGMAGKWHLGVGP 138  

                   evaiidstyyrpqypqwv.apg...............yrrPdireelays
                   e+a+         +p+    +  + + ++++++ ++  ++P+    +  +
   mKIAA4172   139 EGAFL--------PPHQGfHRFlgipyshdqgpcqnlTCFPPD---IPCK 177  

                   grpyngdvpv.l.agspldl.p.....leervdtilkarfqpldlaslew
                   g++ +g vp++l a+ + + +p+  ++le r  ++             + 
   mKIAA4172   178 GGCDQGLVPIpLlANLTVEAqPpwlpgLEARYVSFS------------RD 215  

                   lalsaklpgtderPdllllYleepDsaGHkyGPd.nspeavl........
                   l ++a      +  + ++lY+    ++ H + P+ ++   +++++++++ 
   mKIAA4172   216 LMADAQ-----RQGRPFFLYY----ASHHTHYPQfSGQS-FTkrsgrgpf 255  

                   .dalrrvDraigrLieaLkerglledtnlivvSDHGmapv.kspdkvifl
                   +d l ++D a+g L+ ++ + glle+t +i+++D G + ++ s+ +   l
   mKIAA4172   256 gDSLMELDGAVGALMTTVGDLGLLEETLVIFTADNGPELMrMSNGGCSGL 305  

                   ndpaylpdkgllalkeedledadsasiksdafavsegpvariypnkpgel
                    +  + +   +                       +    a +y  +++ +
   mKIAA4172   306 LR--CGKGTTFE---------------------GGVREPALVYW-PGHIT 331  

                   eevyearqavdelLsklpgvaevskliallegdphvkvylke.dlpkrlh
                   + v ++   ++  L  lp +       a+l g+p  +v l++ d+   l 
   mKIAA4172   332 PGVTHE---LASSLDLLPTL-------AALTGAPLPNVTLDGvDISPLLL 371  

                   y.akn....e.ry.pRigdlvlvadp.Gwyitadyywldekkapdfaktv
                    ++k+++++  +y+p   +++ v   +   + a                 
   mKIAA4172   372 GtGKSprksVfFYpPYPDEIHGVFAVrNGKYKA----------------- 404  

                   dypgGtHGyd<-*
                     ++ t G+    
   mKIAA4172   405 --HFFTQGSA    412  

Sulfatase: domain 1 of 1, from 28 to 448: score 276.6, E = 3.1e-79
                   *->ppnvvlilgESaradrrlnmglyGyprpttPfLsdklaqdeegllFs
                      ppn++li+++++++    ++g yG+p  ttP+L d la  e+gl+F+
   mKIAA4172    28    PPNILLIFADDLGYG---DLGSYGHPSSTTPNL-DQLA--EGGLRFT 68   

                   nfysgapgTapSlfalLtglppsnlgvgvstpyqqvyakgpgydiqlprt
                   +fy+    ++pS++alLtg+ p + g+++  + +  +       ++lp++
   mKIAA4172    69 DFYVPVSLCTPSRAALLTGRLPVRSGMYPGVLGPSSQ-------GGLPLE 111  

                   qpnlpdlLkqaGYrTnfigkwhlswysrqsvykgkktSveaflP.nlGFd
                   + +l+++L ++GY T++ gkwhl+    +++           lP+++GF+
   mKIAA4172   112 EVTLAEVLAARGYLTGMAGKWHLGVGPEGAF-----------LPpHQGFH 150  

                   sffdrnallelyadppdseyylgpgggnn.kgniy.eefaddlalmeCfL
                   +f++  + ++  ++p  + +  +p   +++ +++  ++++         L
   mKIAA4172   151 RFLG--IPYSHDQGPCQNLTCFPPDIPCKgGCDQGlVPIP---------L 189  

                   l.nl.vvaqPp.l.vsDealldkilevL.alqkndkPffivlhtmgsHag
                   l nl+v+aqPp l+   ++   ++ +++ ++q++++Pff++ +++++H  
   mKIAA4172   190 LaNLtVEAQPPwLpGLEARYVSFSRDLMaDAQRQGRPFFLYYASHHTHY- 238  

                   ppiPyypdrypekfakfqptcgeaerscskeqqlnnYlnavaytDdligr
                   p    + + + +                   + +    +++ + D ++g 
   mKIAA4172   239 PQ--FSGQSFTKR------------------SGRGPFGDSLMELDGAVGA 268  

                   liekLkksgkdkntlvvytSDHGpslget.s.tkekkggvylhgektnay
                   l   + + g+++ tlv++t+D+Gp+l  +++++      + l+ +k+++ 
   mKIAA4172   269 LMTTVGDLGLLEETLVIFTADNGPELMRMsNgG----CSGLLRCGKGTTF 314  

                   eggyrvPlliwspdgkpakhpidvqclkgqkikalvshiDlfpTlLdlaG
                   egg r P+l+++p+++ +            ++++l+s+ Dl+pTl  l+G
   mKIAA4172   315 EGGVREPALVYWPGHITP-----------GVTHELASSLDLLPTLAALTG 353  

                   ikktsdvplyyadlteppsnpqagpkyllldgrdtlailegkkilvndgy
                   +                         +++ldg+d+ + l+g         
   mKIAA4172   354 A----------------------PLPNVTLDGVDISPLLLGT-------- 373  

                   rtydgilggyssqsehdslfgyl.k.vr.ddlkavtlyef.ntraivk.g
                              ++s+++s f+y++++ +   ++av++ +++ +++++++ 
   mKIAA4172   374 -----------GKSPRKSVFFYPpYpDEiHGVFAVRNGKYkAHFFTQGsA 412  

                   weavtldp.da.tct.evEffrllkvkpldmsftrdppeLYdlngdlgel
                   + + t dp ++     +                 ++pp+LYdl++d+ge 
   mKIAA4172   413 HSDTTSDPaCHaANRlTA----------------HEPPLLYDLSQDPGEN 446  

                   en<-*
                   +n   
   mKIAA4172   447 YN    448  

//