hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj42151/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA4165  ( 674 res)   mfj42151

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    333.8    1.2e-95   1
S_TK_X   Extension to Ser/Thr-type protein kinases       81.9      8e-20   1
C1       Protein kinase C conserved region 1 (C1) dom    61.8    8.5e-14   1
OPR      Octicosapeptide repeat                          45.5      7e-09   1
TyrKc    Tyrosine kinase, catalytic domain               13.7    5.5e-12   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
OPR        1/1     144   173 ..     1    30 []    45.5    7e-09
C1         1/1     220   269 ..     1    61 []    61.8  8.5e-14
S_TKc      1/1     332   600 ..     1   231 []   333.8  1.2e-95
TyrKc      1/1     332   600 ..     1   280 []    13.7  5.5e-12
S_TK_X     1/1     601   664 ..     1    79 []    81.9    8e-20

Alignments of top-scoring domains:
OPR: domain 1 of 1, from 144 to 173: score 45.5, E = 7e-09
                   *->tvtikYiDeDGDlVtivSdeDleeAlelar<-*
                      ++t k+iDe+GD++t++S+ +leeA++l++   
   mKIAA4165   144    PFTMKWIDEEGDPCTVSSQLELEEAFRLYE    173  

C1: domain 1 of 1, from 220 to 269: score 61.8, E = 8.5e-14
                   *->Hkfvfrtf.kptfCdvCrksiwgsfkqaaksqglrCseCkvkcHkkC
                      H+f++++f++++ C++C ++iwg+ +q     g++C++Ck+ +HkkC
   mKIAA4165   220    HTFQAKRFnRRAHCAICTDRIWGLGRQ-----GYKCINCKLLVHKKC 261  

                   aekvpaqshksglsC<-*
                   ++ v+         C   
   mKIAA4165   262 HKLVTI-------EC    269  

S_TKc: domain 1 of 1, from 332 to 600: score 333.8, E = 1.2e-95
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik..........eril
                      ++ll+++G+G+++kV l+r kkt+r++A+Kv+k++  +++++ + ++
   mKIAA4165   332    FDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKkelvnddediDWVQ 378  

                   rEikiLkk..dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrg
                    E  + ++ ++HP++V L+ +f+++++l++V Ey++G  GdL+ ++++++
   mKIAA4165   379 TEKHVFEQasNHPFLVGLHSCFQTeSRLFFVIEYVNG--GDLMFHMQRQR 426  

                   rrglrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hv
                   +      l+E++arfy ++i +aL+YLH++gIi+RDLK +N+LLds++h+
   mKIAA4165   427 K------LPEeHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSegHI 470  

                   KlaDFGlArql.......ttfvGTpeYmAPEvl...gYgkpavDiWSlGc
                   Kl+D G++++  +++++++tf+GTp+Y+APE+l+++ Yg+ +vD+W+lG+
   mKIAA4165   471 KLTDYGMCKEGlrpgdttSTFCGTPNYIAPEILrgeDYGF-SVDWWALGV 519  

                   ilyElltGkpPFp...........qldlifkkig..........Speakd
                   +++E+++G+ PF+  +++++++++++d +f++i+++  + +++ S  a +
   mKIAA4165   520 LMFEMMAGRSPFDivgssdnpdqnTEDYLFQVILekqiriprslSVKAAS 569  

                   LikklLvkdPekRlta.eaLedeldikaHPff<-*
                    +k  L+kdP++Rl+++       di  HPff   
   mKIAA4165   570 VLKSFLNKDPKERLGChPQTG-FADIQGHPFF    600  

TyrKc: domain 1 of 1, from 332 to 600: score 13.7, E = 5.5e-12
                   *->ltlgkkLGeGaFGeVykGtlk.......ieVAVKtLkeda..keeFl
                        l++++G+G + +V + +lk++++   ++V  K L +d +++    
   mKIAA4165   332    FDLLRVIGRGSYAKVLLVRLKktdriyaMKVVKKELVNDDedIDWVQ 378  

                   rEakiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLld
                    E  +  +   +Hp +V L+ +  +e         l+ v Ey+ gGdL  
   mKIAA4165   379 TEKHVFEQA-SNHPFLVGLHSCFQTE-------SRLFFVIEYVNGGDLMF 420  

                   yLrknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenkv
                   + ++ r+ l+ ++   ++  I+   +YL++++++ RDL   N+L++++++
   mKIAA4165   421 HMQRQRK-LPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGH 469  

                   vKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEslkdg
                   +K +D G+++++             +++   +g         APE l+  
   mKIAA4165   470 IKLTDYGMCKEGLRP-------GDTTSTF--CGTP----NYIAPEILRGE 506  

                   kFtskSDVWSFGVlLWEiftl.......GeqPYpgeiqqfmsneevleyl
                    + +  D W+ GVl++E++  +++ +  G +  p+      + e+ l ++
   mKIAA4165   507 DYGFSVDWWALGVLMFEMMAGrspfdivGSSDNPD-----QNTEDYLFQV 551  

                   kkGyRlpkPendlpiSsvtCPdelYdlMlqCWaedPedRP......tFse
                      +  ++P +         + +  ++ ++  + dP++R + ++++ F++
   mKIAA4165   552 ILEKQIRIPRS--------LSVKAASVLKSFLNKDPKERLgchpqtGFAD 593  

                   l..verl<-*
                   ++++ ++   
   mKIAA4165   594 IqgHPFF    600  

S_TK_X: domain 1 of 1, from 601 to 664: score 81.9, E = 8e-20
                   *->rgiDWdkLenekkeiePPFkPkikeVyAsptDtsNFDkeFteetpvl
                      r++DWd  e+  k++ PPFkP+i+    +++ + NFD  Ft+e++ l
   mKIAA4165   601    RNVDWDMMEQ--KQVVPPFKPNIS----GEFGLDNFDSQFTNEPVQL 641  

                   tpvdsalsnsiqqeeaeteippdpFrGFsyvf<-*
                   tp+d+ +++ i+q+e         F+GF y++   
   mKIAA4165   642 TPDDDDIVRKIDQSE---------FEGFEYIN    664  

//