hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj30170/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA4163  ( 536 res)   mfj30170

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    379.1   2.7e-109   1
TyrKc    Tyrosine kinase, catalytic domain                4.7      2e-11   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
S_TKc      1/1      38   296 ..     1   231 []   379.1 2.7e-109
TyrKc      1/1      38   296 ..     1   280 []     4.7    2e-11

Alignments of top-scoring domains:
S_TKc: domain 1 of 1, from 38 to 296: score 379.1, E = 2.7e-109
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik.........erilr
                      Y+l ++lGkGaF++V+++ ++ tg+++A K+i++++ + +++++++r
   mKIAA4163    38    YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINtkklsardhQKLER 84   

                   EikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgrr
                   E +i++  +HPNIV+L+d++ ++++ ylV++++ G  G+Lf+ ++ r + 
   mKIAA4163    85 EARICRLlKHPNIVRLHDSISEeGFHYLVFDLVTG--GELFEDIVAREY- 131  

                   glrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds.....h
                        +sE +a + ++Qil+ ++++H +gI+HRDLKPeN+LL s++++  
   mKIAA4163   132 -----YSEaDASHCIQQILESVNHCHLNGIVHRDLKPENLLLASkskgaA 176  

                   vKlaDFGlArql.......ttfvGTpeYmAPEvl...gYgkpavDiWSlG
                   vKlaDFGlA +++++++    f GTp Y++PEvl++++Ygk +vD+W++G
   mKIAA4163   177 VKLADFGLAIEVqgdqqawFGFAGTPGYLSPEVLrkdPYGK-PVDMWACG 225  

                   cilyElltGkpPFp..qldlifkkig..............SpeakdLikk
                   +ily+ll+G+pPF+++++++++++i+ + ++ +++++++ +peakdLi+k
   mKIAA4163   226 VILYILLVGYPPFWdeDQHRLYQQIKagaydfpspewdtvTPEAKDLINK 275  

                   lLvkdPekRlta.eaLedeldikaHPff<-*
                   +L+ +P+kR+ta+eaL+       HP++   
   mKIAA4163   276 MLTINPAKRITAsEALK-------HPWI    296  

TyrKc: domain 1 of 1, from 38 to 296: score 4.7, E = 2e-11
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda.....keeFlr
                       +l ++LG GaF +V++++ +++++e A K ++  + + ++++ + r
   mKIAA4163    38    YQLFEELGKGAFSVVRRCMKIptgQEYAAKIINTKKlsardHQKLER 84   

                   EakiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldy
                   Ea+i + l  kHpNiV+L+  ++ee       + +++v+ ++ gG L + 
   mKIAA4163    85 EARICRLL--KHPNIVRLHDSISEE-------GFHYLVFDLVTGGELFED 125  

                   LrknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenk..
                   + +++   s +d  +   QI +  ++ + +++vHRDL   N L++++ ++
   mKIAA4163   126 IVAREY-YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSkg 174  

                   .vvKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEslk
                     vK +DFGL+ ++  d      +     +   g+ +      ++PE+l+
   mKIAA4163   175 aAVKLADFGLAIEVQGD-----QQAWFGFA---GTPG-----YLSPEVLR 211  

                   dgkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGyR
                   +  +    D W+ GV L+ i+  G +P ++      +  ++++++k+G +
   mKIAA4163   212 KDPYGKPVDMWACGVILY-ILLVGYPPFWD-----EDQHRLYQQIKAGAY 255  

                   lpkPendlpiSsvtCPdelYdlMlqCWaedPedRPtFsel..verl<-*
                     + ++       t ++e  dl+ +    +P++R t se  ++  +   
   mKIAA4163   256 DFPSPE-----WDTVTPEAKDLINKMLTINPAKRITASEAlkHPWI    296  

//