hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj30170/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4163  ( 536 res)   mfj30170

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       348.3   8.6e-101   1
Pkinase_Tyr Protein tyrosine kinase                       8.2    2.2e-12   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase_Tyr   1/1      38   294 ..     1   272 []     8.2  2.2e-12
Pkinase       1/1      38   296 ..     1   287 []   348.3 8.6e-101

Alignments of top-scoring domains:
Pkinase_Tyr: domain 1 of 1, from 38 to 294: score 8.2, E = 2.2e-12
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtL.keigasseei
                       +l ++LG+GaF +V+++        t+++ A K+++ + + s ++ 
   mKIAA4163    38    YQLFEELGKGAFSVVRRCMKI----PTGQEYAAKIInTK-KLSARD- 78   

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                    ++++ rEA+i + l +HpNiVrL+  +++ ++     +y+V+ ++ gG 
   mKIAA4163    79 -HQKLEREARICRLL-KHPNIVRLHDSISE-EGF----HYLVFDLVTGGE 121  

                   LldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLV
                   L +   +   ++  + +d  +  +Qi +  ++ + +++vHRDL   N L+
   mKIAA4163   122 LFEDIVA---REYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLL 168  

                   se...nlvVKIsDFGLaRdiynddyYvrkkgggk.lPvkWmAPEslkygk
                   ++++++  VK +DFGLa  +   d   ++   g       ++PE+l+   
   mKIAA4163   169 ASkskGAAVKLADFGLAIEV-QGD---QQAWFGFaGTPGYLSPEVLRKDP 214  

                   FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPen
                   +    D W+ GV L+ ++  G +P +++ + +++++++    y  p Pe 
   mKIAA4163   215 YGKPVDMWACGVILYILLV-GYPP-FWDEDQHRLYQQIKAGAYDFPSPEW 262  

                   C..PdelYdlMlqCWaedPedRPtFselverL<-*
                    + ++e  dl+ +    +P++R t se + +    
   mKIAA4163   263 DtvTPEAKDLINKMLTINPAKRITASEALKHP    294  

Pkinase: domain 1 of 1, from 38 to 296: score 348.3, E = 8.6e-101
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      y+l e lG+G+f++V++++++ tg+++A Kii+ +k +   ++ + r
   mKIAA4163    38    YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 84   

                   rsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrlldLfdylse
                     E++i + L+HpNIvrl+d+  +++  ylV++++ gG    +Lf+ +  
   mKIAA4163    85 --EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG----ELFEDIV- 127  

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILld..en
                     ++  +  se +a +++ Qil+ ++++H ngi+HRDLKPeN+Ll ++++
   mKIAA4163   128 --AREYY--SEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLAskSK 173  

                   gvvdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtk
                   g     +K+aDFGlA  +  + ++   +f+GTp+Y++PEvl+   +yg++
   mKIAA4163   174 GAA---VKLADFGLAIEV-QgDQQaWFGFAGTPGYLSPEVLR-KDPYGKP 218  

                   vDvWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewd
                   vD+W++Gvily+ll G+pPF++e     dq  l+++i+ + ++f+spewd
   mKIAA4163   219 VDMWACGVILYILLVGYPPFWDE-----DQHRLYQQIKAGAYDFPSPEWD 263  

                   sisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                    +            +eakdLi+k+L+ +P+kR+ta e+l+HPw+   
   mKIAA4163   264 TVT-----------PEAKDLINKMLTINPAKRITASEALKHPWI    296  

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