hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mid/mid27006/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4159  ( 511 res)   mid27006

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
CUB      CUB domain                                     447.3   1.3e-130   3
Astacin  Astacin (Peptidase family M12A)                248.4    9.9e-71   1
EGF_CA   Calcium binding EGF domain                      29.9    5.8e-05   1
EGF      EGF-like domain                                 29.8    6.4e-05   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Astacin    1/1       2   178 ..     1   200 []   248.4  9.9e-71
CUB        1/3     179   288 ..     1   116 []   204.3  1.9e-57
CUB        2/3     292   401 ..     1   116 []   230.4  2.7e-65
EGF        1/1     408   444 ..     1    39 []    29.8  6.4e-05
EGF_CA     1/1     405   444 ..     1    55 []    29.9  5.8e-05
CUB        3/3     448   511 .]     1   116 []    23.6    4e-06

Alignments of top-scoring domains:
Astacin: domain 1 of 1, from 2 to 178: score 248.4, E = 9.9e-71
                   *->rrWpngsnGiVvIPYvidssysgreralIrqAmrhweqkTCirFvpr
                         +++s     IP   ++s s + r++I++              p 
   mKIAA4159     2    ---TGRS-----IP--VSPSWSAQMRTAILYS-------------PT 25   

                   tsagendylrffsgdGCySyVGraggGaQevSlGanGCdyfGiIvHElgH
                   ++a   +  +  +++ C+SyVGr+ggG+Q++S+G ++Cd+fGi+vHElgH
   mKIAA4159    26 DPAARDHPPELAPPSRCCSYVGRRGGGPQAISIG-KNCDKFGIVVHELGH 74   

                   ALGFyHEQsRpDRDdyVtInwqNIdpgqegnFdKydpdevdslGvpYDYg
                   ++GF+HE++RpDRD++V+I+++NI+pgqe+nF K+  +ev+slG++YD++
   mKIAA4159    75 VIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFD 124  

                   SIMHYgryaFSknggkpTIvpkdne.iyqatIGQReglSfiDikkiNklY
                   SIMHY+r++FS+++ ++TIvpk ++++ ++ IGQR +lS++Di+++ klY
   mKIAA4159   125 SIMHYARNTFSRGIFLDTIVPKYEVnGVKPSIGQRTRLSKGDIAQARKLY 174  

                   kCse<-*
                   kC+    
   mKIAA4159   175 KCPA    178  

CUB: domain 1 of 3, from 179 to 288: score 204.3, E = 1.9e-57
                   *->CGgtldltessGsitSPnYPnrdYppnkeCvWrIrappgyrvVeLtF
                      CG+t  l++s+G+++SP+YPn  Y+ +++CvWrI+++pg++ + L+F
   mKIAA4159   179    CGET--LQDSTGNFSSPEYPN-GYSAHMHCVWRISVTPGEK-IILNF 221  

                   qdFdlEdhdgaCryDyvEirDGdpssspllGrfCGgsgpPedirStsnrm
                   +++dl++++  C+yDyvE+rDG+++++pl+GrfCG  ++Pe+i+St++r+
   mKIAA4159   222 TSMDLYRSRL-CWYDYVEVRDGFWRKAPLRGRFCG-GKLPEPIVSTDSRL 269  

                   likFvsDasvqkrGFkAty<-*
                   +++F s++++ ++GF+A y   
   mKIAA4159   270 WVEFRSSSNWVGKGFFAVY    288  

CUB: domain 2 of 3, from 292 to 401: score 230.4, E = 2.7e-65
                   *->CGgtldltessGsitSPnYPnrdYppnkeCvWrIrappgyrvVeLtF
                      CGg+  +++ +G+i+SPnYP+ dY+p+k C+WrI++ +g++ V LtF
   mKIAA4159   292    CGGD--VKKDNGHIQSPNYPD-DYRPSKVCIWRIQVSEGFH-VGLTF 334  

                   qdFdlEdhdgaCryDyvEirDGdpssspllGrfCGgsgpPedirStsnrm
                   q+F++E+hd+ C+yDy+E+rDG+++ss l+Gr+CG +++P+di+Sts+r+
   mKIAA4159   335 QSFEIERHDS-CAYDYLEVRDGHSESSNLIGRYCG-YEKPDDIKSTSSRL 382  

                   likFvsDasvqkrGFkAty<-*
                   ++kFvsD+s++k+GF+ ++   
   mKIAA4159   383 WLKFVSDGSINKAGFAVNF    401  

EGF: domain 1 of 1, from 408 to 444: score 29.8, E = 6.4e-05
                   *->Cspnn.gpCsngGtCvdtpggytCeCppGdyfllytGkrC<-*
                      Cs  n+g+C    +C++t g+y+C C+pG y l+ + +rC   
   mKIAA4159   408    CSRPNrGGCEQ--RCLNTLGSYKCSCDPG-YELAPDKRRC    444  

EGF_CA: domain 1 of 1, from 405 to 444: score 29.9, E = 5.8e-05
                   *->DvDECatgtlhvCpDpdentvCvNtiGSFeCvarkdCpeGYeVpvse
                       vDEC  +    C        C+Nt GS++C+    C++GYe     
   mKIAA4159   405    -VDECSRPNRGGC-----EQRCLNTLGSYKCS----CDPGYE----- 436  

                   nnedgtnC<-*
                     +d   C   
   mKIAA4159   437 LAPDKRRC    444  

CUB: domain 3 of 3, from 448 to 511: score 23.6, E = 4e-06
                   *->CGgtldltessGsitSPnYPnrdYppnkeCvWrIrappgyrvVeLtF
                      CGg   lt+ +GsitSP++P+ +Yppnk+C+W+++ap +yr ++L+F
   mKIAA4159   448    CGGF--LTKLNGSITSPGWPK-EYPPNKNCIWQLVAPTQYR-ISLQF 490  

                   qdFdlEdhdgaCryDyvEirDGdpssspllGrfCGgsgpPedirStsnrm
                   + F++E+            +DG +            s+  + + S     
   mKIAA4159   491 DFFETEG------------NDGVS------------SPERGSLQS----- 511  

                   likFvsDasvqkrGFkAty<-*
                                         
   mKIAA4159     - -------------------    -    

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