hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpf/mpf00123/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4135  ( 723 res)   mpf00123

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
CUE        CUE domain                                    40.6    3.5e-08   1
zf-RanBP   Zn-finger in Ran binding protein and other    25.0     0.0018   1
Extensin_2 Extensin-like region                        -140.7       0.56   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
CUE          1/1      15    57 ..     1    43 []    40.6  3.5e-08
Extensin_2   1/1     124   459 ..     1   385 []  -140.7     0.56
zf-RanBP     1/1     693   723 .]     1    32 []    25.0   0.0018

Alignments of top-scoring domains:
CUE: domain 1 of 1, from 15 to 57: score 40.6, E = 3.5e-08
                   *->vneealhelkemFPqldksvIravLeantgnveatinnLLegs<-*
                         ++lh+l++ FP+++++v+++++++n++n+ea++ +L ++s   
   mKIAA4135    15    LDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQES    57   

Extensin_2: domain 1 of 1, from 124 to 459: score -140.7, E = 0.56
                   *->lltlvvalvslslpseasakYsY........sSPPPpekpYvYkSPP
                      l+ lv  + s      a+++Y +   +++++s   Pp       S P
   mKIAA4135   124    LICLVQEPHSAPAVVAATPNYNPffmneqnrSAATPP-------SQP 163  

                   pPspkyvykSPPPpkkpYvYsSPPPPsyvykSPPPPkpyvYkSPPpPkyv
                   p  p        P+      + P PP      PPPP    Y   P+    
   mKIAA4135   164 PQQPSSMQTGMNPS----AMQGPSPP------PPPP---SYMHIPR---- 196  

                   YkSPPpPvykYkSPPPPthsppPpyvykSPPPPpkkyvykSpPpptPvYk
                   Y+  P  v + +  P       P+     P  P+    y Sp  +   ++
   mKIAA4135   197 YSTNPITVTVSQNLPSGQ--TVPRALQILPQIPS--NLYGSPGSI---FI 239  

                   YkSPPPPp........yvYkspPpPvkkripyvYkSPPPPpPYvYkSpPp
                    +     ++++++++ +   sp  Pv++     Y+  P P+ Y  +    
   mKIAA4135   240 RQTSQSSSgrqtpqnaPWQSSPQGPVPH-----YSQRPLPV-YPHQQNYQ 283  

                   pvkkyiyksppppephkYvYkSPPP...PpPYvyesvpeqkikYvYkSPP
                   p+ +y   sp   + ++ vY SPPP++ P+P   +s p+++++       
   mKIAA4135   284 PS-QY---SPKQQQIPQSVYHSPPPsqcPSP---FSSPQHQVQ------- 319  

                   PPkksYkspsppkyVYkSp.PpPvipykYkSPPPPkkkyspaPrkpyvYk
                   PP+       p + V+  p+P  ++p+ Y+   PP+++ + +  + y   
   mKIAA4135   320 PPQ----LGHPSSHVFMPPsPSTTPPHLYQ-QGPPSYQKPGSHSVAYL-- 362  

                   SPPPPtyvYkSpPpPykpptppkiyksPPPPtPvyvYkspPpippiksss
                        +y   S P  +       +  s  P t     +sp pi   ++s+
   mKIAA4135   363 -----PYTASSLPKGSMKKIEITVEPSQRPGT--AITRSPSPISN-QPSP 404  

                   ppPvyvYkSpPppvysPPPPyvYssPPPPvyvynsaPvykk.sPPkhhYi
                         Y    pp+ sP    + s P PP    +  Pvy+  + P  +  
   mKIAA4135   405 RNQHSLYTATTPPSSSPSRG-ISSQPKPPF---SVNPVYITyTQPTGPSC 450  

                   YsSPPPphh<-*
                     SP P +    
   mKIAA4135   451 APSPSPRVI    459  

zf-RanBP: domain 1 of 1, from 693 to 723: score 25.0, E = 0.0018
                   *->ragsdWdCissClvqNfatstkCvaCqapkps<-*
                       +g  W+C +sC++ N +  ++C +C+ p++    
   mKIAA4135   693    YEGAPWNC-DSCTFLNHPALNRCEQCEMPRYT    723  

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