hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/Pfam Sequence file: /cdna4/rodent/full/goal/mid/mid39041/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA4111 ( 619 res) mid39041 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- LRR_1 Leucine Rich Repeat 185.6 7.7e-52 19 LRRNT Leucine rich repeat N-terminal domain 51.3 2.1e-11 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- LRRNT 1/1 56 89 .. 1 34 [] 51.3 2.1e-11 LRR_1 1/19 91 114 .. 1 25 [] 15.9 0.95 LRR_1 2/19 115 138 .. 1 25 [] 8.4 82 LRR_1 3/19 139 162 .. 1 25 [] 12.0 15 LRR_1 4/19 163 186 .. 1 25 [] 13.6 4.7 LRR_1 5/19 187 210 .. 1 25 [] 8.8 69 LRR_1 6/19 211 234 .. 1 25 [] 12.8 8.1 LRR_1 7/19 235 258 .. 1 25 [] 15.8 1 LRR_1 8/19 259 282 .. 1 25 [] 12.5 10 LRR_1 9/19 283 306 .. 1 25 [] 14.0 3.5 LRR_1 10/19 307 330 .. 1 25 [] 12.3 12 LRR_1 11/19 331 354 .. 1 25 [] 12.5 10 LRR_1 12/19 355 378 .. 1 25 [] 8.8 70 LRR_1 13/19 379 402 .. 1 25 [] 14.3 2.9 LRR_1 14/19 403 426 .. 1 25 [] 9.4 55 LRR_1 15/19 427 450 .. 1 25 [] 15.3 1.5 LRR_1 16/19 451 474 .. 1 25 [] 13.2 6.5 LRR_1 17/19 475 498 .. 1 25 [] 15.8 1 LRR_1 18/19 499 522 .. 1 25 [] 9.4 55 LRR_1 19/19 523 547 .. 1 25 [] 12.7 9.1 Alignments of top-scoring domains: LRRNT: domain 1 of 1, from 56 to 89: score 51.3, E = 2.1e-11 *->aCpapCtCser.ytdglvVdCsgrgLtvavPrdlP<-* +Cp+ CtCs+++ytd+l+V+Cs+r+Lt ++P+ +P mKIAA4111 56 QCPVTCTCSYDdYTDELSVFCSSRNLT-QLPDSIP 89 LRR_1: domain 1 of 19, from 91 to 114: score 15.9, E = 0.95 *->nLeeLdLsgCNpslsgslpps.l.glp<-* + + L L+g N +ls s+p+ ++++l+ mKIAA4111 91 STRALWLDG-N-NLS-SIPSAaFqNLS 114 LRR_1: domain 2 of 19, from 115 to 138: score 8.4, E = 82 *->nLeeLdLsgCNpslsgslpps.l.glp<-* +L L+L+g + l +sl+p +l gl+ mKIAA4111 115 SLDFLNLQG-S-WL-RSLEPQaLlGLQ 138 LRR_1: domain 3 of 19, from 139 to 162: score 12.0, E = 15 *->nLeeLdLsgCNpslsgslpps.l.glp<-* nL +L+L++ N l +sl+++ +++ p mKIAA4111 139 NLYHLHLER-N-LL-RSLAAGlFrHTP 162 LRR_1: domain 4 of 19, from 163 to 186: score 13.6, E = 4.7 *->nLeeLdLsgCNpslsgslpps.l.glp<-* +L +L+L++ N l g l+++ ++gl+ mKIAA4111 163 SLASLSLGN-N-LL-GRLEEGlFrGLS 186 LRR_1: domain 5 of 19, from 187 to 210: score 8.8, E = 69 *->nLeeLdLsgCNpslsgslpps.l.glp<-* +L L+L+ N sl lp+ ++gl mKIAA4111 187 HLWDLNLGW-N-SLV-VLPDTvFqGLG 210 LRR_1: domain 6 of 19, from 211 to 234: score 12.8, E = 8.1 *->nLeeLdLsgCNpslsgslpps.l.glp<-* nL eL L g N +l+ l+p l gl mKIAA4111 211 NLHELVLAG-N-KLT-YLQPAlLcGLG 234 LRR_1: domain 7 of 19, from 235 to 258: score 15.8, E = 1 *->nLeeLdLsgCNpslsgslpps.l.glp<-* +L+eLdLs+ N l +s+ ++ + +lp mKIAA4111 235 ELRELDLSR-N-AL-RSVKANvFiHLP 258 LRR_1: domain 8 of 19, from 259 to 282: score 12.5, E = 10 *->nLeeLdLsgCNpslsgslpps.l.glp<-* +L++L+L++ N ++ ++p ++ g++ mKIAA4111 259 RLQKLYLDR-N-LIT-AVAPRaFlGMK 282 LRR_1: domain 9 of 19, from 283 to 306: score 14.0, E = 3.5 *->nLeeLdLsgCNpslsgslppsl.glp<-* L++LdLs+ N ++ g l++ ++gl mKIAA4111 283 ALRWLDLSH-N-RVAGLLEDTFpGLL 306 LRR_1: domain 10 of 19, from 307 to 330: score 12.3, E = 12 *->nLeeLdLsgCNpslsgslpps.l.glp<-* L +L+L + N ++ sl p ++++l mKIAA4111 307 GLHVLRLAH-N-AIT-SLRPRtFkDLH 330 LRR_1: domain 11 of 19, from 331 to 354: score 12.5, E = 10 *->nLeeLdLsgCNpslsgslpps.l.glp<-* LeeL L++ N ++ + l + +++gl mKIAA4111 331 FLEELQLGH-N-RI-RQLGEKtFeGLG 354 LRR_1: domain 12 of 19, from 355 to 378: score 8.8, E = 70 *->nLeeLdLsgCNpslsgslpps.l.glp<-* +Le+L L++ N ++ ++ +++ gl mKIAA4111 355 QLEVLTLND-N-QIH-EVKVGaFfGLF 378 LRR_1: domain 13 of 19, from 379 to 402: score 14.3, E = 2.9 *->nLeeLdLsgCNpslsgslpps.l.glp<-* n+ + +Lsg N l +slp++ ++gl mKIAA4111 379 NVAVMNLSG-N-CL-RSLPEHvFqGLG 402 LRR_1: domain 14 of 19, from 403 to 426: score 9.4, E = 55 *->nLeeLdLsgCNpslsgslpps.l.glp<-* +L +L+L++ + l g + +++ gl+ mKIAA4111 403 RLHSLHLEH-S-CL-GRIRLHtFaGLS 426 LRR_1: domain 15 of 19, from 427 to 450: score 15.3, E = 1.5 *->nLeeLdLsgCNpslsgslpps.l.glp<-* L+ L L++ N s+s s+++ +l gl+ mKIAA4111 427 GLRRLFLRD-N-SIS-SIEEQsLaGLS 450 LRR_1: domain 16 of 19, from 451 to 474: score 13.2, E = 6.5 *->nLeeLdLsgCNpslsgslpps.l.glp<-* +L eLdL N +l+ +lp ++gl mKIAA4111 451 ELLELDLTA-N-QLT-HLPRQlFqGLG 474 LRR_1: domain 17 of 19, from 475 to 498: score 15.8, E = 1 *->nLeeLdLsgCNpslsgslpps.l.glp<-* +Le+L Ls+ N +l+ l+++ l+ l+ mKIAA4111 475 QLEYLLLSN-N-QLT-MLSEDvLgPLQ 498 LRR_1: domain 18 of 19, from 499 to 522: score 9.4, E = 55 *->nLeeLdLsgCNpslsgslpps.l.glp<-* + +LdLs+ N +l+ + +++ +++l mKIAA4111 499 RAFWLDLSH-N-RLE-TPAEGlFsSLG 522 LRR_1: domain 19 of 19, from 523 to 547: score 12.7, E = 9.1 *->nLeeLdLsgCNpslsgs.lpps.l.glp<-* +L++L+L++ N sl+ + +p +l+ l mKIAA4111 523 RLRYLNLRN-N-SLQ-TfVPQPgLeRLW 547 //