hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj68342/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4107  ( 1176 res)   mfj68342

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       207.9    1.6e-58   1
Pkinase_Tyr Protein tyrosine kinase                     -46.1    5.3e-09   1
Kdo         Lipopolysaccharide kinase (Kdo/WaaP) fami   -86.7       0.54   1
RIO1        RIO1 family                                -105.4       0.85   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
RIO1          1/1     204   357 ..     1   203 []  -105.4     0.85
Kdo           1/1     201   368 ..     1   223 []   -86.7     0.54
Pkinase_Tyr   1/1     206   431 ..     1   272 []   -46.1  5.3e-09
Pkinase       1/1     206   534 ..     1   287 []   207.9  1.6e-58

Alignments of top-scoring domains:
RIO1: domain 1 of 1, from 204 to 357: score -105.4, E = 0.85
                   *->nVYhAvsyaedgedptevAvKiyrtgtteFkkrkkYrdgdfRFrdrk
                      n Y+++   ++g++    +vK  + gt+e   +k         r + 
   mKIAA4107   204    NTYEVLEFLGRGTF--GQVVKCWKRGTNEIVAIKILKNHPSYARQG- 247  

                   sktswrklvrlWAe.KEfrNLkRLyeaGvpVPkPiavnrh.vLVMEfIgd
                    ++    l+rl++e+    N +R+ye          +++h++LV E++  
   mKIAA4107   248 -QIEVSILARLSTEsADDYNFVRAYEC-------FQHKNHtCLVFEMLE- 288  

                   edGvpAPrLkdveleldlseeeaeelYdeiirEymrrlYkeagLVHGDLS
                           Lk + +++ l+   ++ +++++       ++k  gL+H+DL 
   mKIAA4107   289 --QNLYDFLKQNKFSP-LPLKYIRPVLQQVAT--ALMKLKSLGLIHADLK 333  

                   EYNiLvhddgkpviIDvsQaVetdHPnAlefLeRDieNIinFFrrkgvdk
                     Ni++ d             +                     r+ +  k
   mKIAA4107   334 PENIMLVDP------------S---------------------RQPYRVK 350  

                   rvvdvrel<-*
                    v+d+ ++   
   mKIAA4107   351 -VIDFGSA    357  

Kdo: domain 1 of 1, from 201 to 368: score -86.7, E = 0.54
                   *->defWqlqgkvvgeanGRrttwFvvaeklFGvngalrhYyRG...glw
                          +   +v++ + GR+t  F++  k          + RG++++  
   mKIAA4107   201    --SMTNTYEVLEFL-GRGT--FGQVVK---------CWKRGtneIVA 233  

                   gkLvrDryrfpGlgrtrsvr.EfrllrrLreaGvpVPkpvAagavkvgle
                    k+ ++   +p  +++r  + E++ l rL  +  +    v a++    ++
   mKIAA4107   234 IKILKN---HP--SYARQGQiEVSILARLSTESADDYNFVRAYEC---FQ 275  

                   r.yqAdLLtEklegaqDLvtwlaqWaddPpaeelrqalweavGrlIakmH
                    + +  L+ E le  q L+++l q    P++ +  + ++++v+++  k+ 
   mKIAA4107   276 HkNHTCLVFEMLE--QNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLK 323  

                   ragvnHtDLnahnILldqeesvegkfkvwlIDfdKcrrrlrvgdrWrekn
                   ++g+ H+DL + nI l ++   ++  +v +IDf  + + +          
   mKIAA4107   324 SLGLIHADLKPENIMLVDPS--RQPYRVKVIDFGSASHVS---------- 361  

                   LarLkRSflKErGkrsigfteaDwaallrgY<-*
                                            a++++Y   
   mKIAA4107   362 ------------------------KAVCSTY    368  

Pkinase_Tyr: domain 1 of 1, from 206 to 431: score -46.1, E = 5.3e-09
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtLkeigasseeie
                       + ++ LG+G FG V+k+  +    gt+  VA+K+Lk+ + s     
   mKIAA4107   206    YEVLEFLGRGTFGQVVKCWKR----GTNEIVAIKILKN-HPSYA--- 244  

                   redFlrEAsiMkklGdHp.....NiVrLlGvctkegePggpglyiVtEym
                    +  + E+si+ +l + ++ ++ N Vr + +  + +       ++V+E+ 
   mKIAA4107   245 -RQGQIEVSILARL-STEsaddyNFVRAYECFQH-KNH----TCLVFEML 287  

                   egGdLldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAAR
                   e  +L+dfL+++   +pL+lk    + +Q+A ++  L s +++H DL   
   mKIAA4107   288 EQ-NLYDFLKQN-KFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPE 335  

                   NcLVse....nlvVKIsDFG....LaRdi...ynddyYvrkkgggklPvk
                   N+++ ++++++  VK+ DFG+ ++ ++++ ++y  + Y            
   mKIAA4107   336 NIMLVDpsrqPYRVKVIDFGsashVSKAVcstYLQSRY------------ 373  

                   WmAPEslkygkFtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlelly
                     APE +    F ++ D WS G+++ E+f  G +  Ypg s ++ + ++ 
   mKIAA4107   374 YRAPEIILGLPFCEAIDMWSLGCVIAELFL-GWPL-YPGASEYDQIRYI- 420  

                   edGyRLprPenCPdelYdlMlqCWaedPedRPtFselverL<-*
                    + + Lp+                                L   
   mKIAA4107   421 SQTQGLPAE------------------------------YL    431  

Pkinase: domain 1 of 1, from 206 to 534: score 207.9, E = 1.6e-58
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      ye+le lG+G+fG+V k+ ++gt++iVA+Ki+k +     + ++   
   mKIAA4107   206    YEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI--- 249  

                   rsEiqilkrLs.....HpNIvrlidvfedkdhlylVlEycegGLrlldLf
                     E++il+rLs+++ +  N vr +++f+ k+h +lV+E +e       L+
   mKIAA4107   250 --EVSILARLStesadDYNFVRAYECFQHKNHTCLVFEMLEQ-----NLY 292  

                   dylsetrrkgpll.fsedeakkialQilrgleYLHsngiiHRDLKPeNIL
                   d+l+    ++++++++ + ++ ++ Q++ +l  L s g iH DLKPeNI+
   mKIAA4107   293 DFLK----QNKFSpLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIM 338  

                   ldengvvdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggng
                   l++    + ++K++DFG+A    + s+  ++t+  +++Y+APE++l g +
   mKIAA4107   339 LVDPSRQPYRVKVIDFGSAS---HvSKAvCSTYLQSRYYRAPEIIL-GLP 384  

                   ygtkvDvWSlGvilyelltGkpPFsgevqds.ldqlqlirkilgpplefd
                      ++D+WSlG++++el++G p+++g+   s++dq+  i +++g p e+ 
   mKIAA4107   385 FCEAIDMWSLGCVIAELFLGWPLYPGA---SeYDQIRYISQTQGLPAEYL 431  

                   spewdsisrse.fr....................................
                           r++++ ++++ +  + +++++++ +++ ++++ ++   +  +
   mKIAA4107   432 LSAGTKTTRFFnRDtdspyplwrlktpddheaetgikskearkyifncld 481  

                   ...............r.l.pnlseeakdLikkcLnkDPskRltaeeilqH
                   +  + + +++ +++++ ++++  +e++dL+kk+L+ D  kR t+ e l+H
   mKIAA4107   482 dmaqvnmttdlegsdMlVeKADRREFIDLLKKMLTIDADKRVTPIETLNH 531  

                   Pwf<-*
                   P++   
   mKIAA4107   532 PFV    534  

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