hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs Sequence file: /cdna4/rodent/full/goal/mbg/mbg12616/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA4089 ( 1251 res) mbg12616 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- TSP1 Thrombospondin type 1 repeats 213.3 2.2e-59 4 HormR Domain present in hormone receptors 82.7 4.5e-20 1 GPS G-protein-coupled receptor proteolytic site 76.9 2.5e-18 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- TSP1 1/4 21 71 .. 1 66 [] 38.2 1.1e-06 TSP1 2/4 76 126 .. 1 66 [] 68.8 6.8e-16 TSP1 3/4 134 184 .. 1 66 [] 64.3 1.6e-14 TSP1 4/4 189 239 .. 1 66 [] 65.5 6.6e-15 HormR 1/1 241 307 .. 1 89 [] 82.7 4.5e-20 GPS 1/1 544 602 .. 1 51 [] 76.9 2.5e-18 Alignments of top-scoring domains: TSP1: domain 1 of 4, from 21 to 71: score 38.2, E = 1.1e-06 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg eWs+WS CS tCG+G ++tRt + c + mKIAA4089 21 AEEWSPWSVCS-STCGEG-----WQTRT-----HFCVSSSY-----S 51 epCs....EtrpCntqpnLqpCp<-* +Cs++ +E+r Cn + ++Cp mKIAA4089 52 TQCSgplrEQRLCNNS---AVCP 71 TSP1: domain 2 of 4, from 76 to 126: score 68.8, E = 6.8e-16 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg w eWs+WS CS tCG+G +r RtR +c+pp+ +gg mKIAA4089 76 WDEWSPWSLCS-STCGRG-----FRDRTR-----TCRPPQ----FGG 107 epCs....EtrpCntqpnLqpCp<-* pC++++++t+ Cn Cp mKIAA4089 108 NPCEgpekQTKFCNIA----LCP 126 TSP1: domain 3 of 4, from 134 to 184: score 64.3, E = 1.6e-14 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg w eWs+WS+CS ++C G +++RtR c++p+ gg mKIAA4089 134 WNEWSSWSTCS-ASCSQG-----RQQRTR-----ECNGPS----YGG 165 epCs....EtrpCntqpnLqpCp<-* ++C+++ Etr+C++q Cp mKIAA4089 166 AECQghwvETRDCFLQ----QCP 184 TSP1: domain 4 of 4, from 189 to 239: score 65.5, E = 6.6e-15 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg w +W +W++CS vtCGgG ++R+R +cs+p +gg mKIAA4089 189 WQAWASWGSCS-VTCGGG-----SQRRER-----VCSGPF----FGG 220 epCs....EtrpCntqpnLqpCp<-* + C+++++E+r+C q Cp mKIAA4089 221 AACQgpqdEYRQCGAQ----RCP 239 HormR: domain 1 of 1, from 241 to 307: score 82.7, E = 4.5e-20 *->tdlgCpatwDgiiCWpsTpaGqlvavpCPeyfsgfsnktggNrtqGn +++ C +++ g + W++TpaG+++av CP++++g+ mKIAA4089 241 PHEICDEDNFGAVVWKETPAGEVAAVRCPRNATGL------------ 275 asRnCtedt.GvGgWsepfpgaeSnrtWpnysnCtsndyeelk<-* + R+C +d++G++ W++ p y++C s+dy++++ mKIAA4089 276 ILRRCELDEeGIAFWEP-----------PTYIRCVSIDYRNIQ 307 GPS: domain 1 of 1, from 544 to 602: score 76.9, E = 2.5e-18 *->snpiCvfWdese.........tgeWstrGCelvetnkpthttCsCnH +n++C Wde+++++++ ++++g Ws+rGC++v++++ +t+C+C++ mKIAA4089 544 TNQTCILWDETDgpsssappqLGPWSWRGCRTVPLDA-LRTRCLCDR 589 LTsFAvLmdvspn<-* L++FA+L+++s++ mKIAA4089 590 LSTFAILAQLSAD 602 //