hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mph/mph00951/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4088  ( 652 res)   mph00951

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    358.9   3.3e-103   1
TyrKc    Tyrosine kinase, catalytic domain               95.0    8.8e-24   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TyrKc      1/1      78   326 ..     1   280 []    95.0  8.8e-24
S_TKc      1/1      78   328 ..     1   231 []   358.9 3.3e-103

Alignments of top-scoring domains:
TyrKc: domain 1 of 1, from 78 to 326: score 95.0, E = 8.8e-24
                   *->ltlgkkLGeGaFGeVykGtlk..ieVAVKtLkeda......keeFlr
                       +++++LG G +G+V k++ ++++ VA+K++++d+ ++++++  ++r
   mKIAA4088    78    YEFLETLGKGTYGKVKKARESsgRLVAIKSIRKDKikdeqdLLHIRR 124  

                   EakiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldy
                   E++iM++l  +Hp+i++++ v   +         + ivmEy++ GdL dy
   mKIAA4088   125 EIEIMSSL--NHPHIIAIHEVFENS-------SKIVIVMEYASRGDLYDY 165  

                   LrknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenkvv
                   + + rp+ls +d  +f  QI +   Y +++++vHRDL   N+L+++n+ +
   mKIAA4088   166 I-SERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNI 214  

                   KIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEslkdgk
                   KI+DFGLs   + +      k   +     +g    P+   +PE  + + 
   mKIAA4088   215 KIADFGLSNLYHKG------KFLQTF----CG---SPL-YASPEIVNGKP 250  

                   F.tskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGyRlp
                   +  ++ D WS GVlL+ i+  G +P  g      + + +++++ +G +++
   mKIAA4088   251 YvGPEVDSWSLGVLLY-ILVHGTMPFDG-----QDHKTLVKQISNGAYRE 294  

                   kPendlpiSsvtCPdelYd.lMlqCWaedPedRPtFselverl<-*
                   +P+                +l+++  + +P  R t +++ + +   
   mKIAA4088   295 PPKP-----------SDACgLIRWLLMVNPTRRATLEDVASHW    326  

S_TKc: domain 1 of 1, from 78 to 328: score 358.9, E = 3.3e-103
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik..........eril
                      Ye+l++lGkG++GkV++ar+ + grlvAiK i++++ +++++  +i+
   mKIAA4088    78    YEFLETLGKGTYGKVKKARESS-GRLVAIKSIRkdkikdeqdlLHIR 123  

                   rEikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgr
                   rEi+i+++ +HP+I+ +++vfe+++k+ +VmEy++   GdL+d++ +r+r
   mKIAA4088   124 REIEIMSSlNHPHIIAIHEVFENsSKIVIVMEYASR--GDLYDYISERPR 171  

                   rglrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvK
                         lsE++ar++frQi+saL Y+H++gI+HRDLK eNiLLd ++++K
   mKIAA4088   172 ------LSErDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDAngNIK 215  

                   laDFGlArql......ttfvGTpeYmAPEvl....gYgkpavDiWSlGci
                   +aDFGl+ ++++++   tf+G+p Y +PE++++++  g+ +vD WSlG++
   mKIAA4088   216 IADFGLSNLYhkgkflQTFCGSPLYASPEIVngkpYVGP-EVDSWSLGVL 264  

                   lyElltGkpPFp..qldlifkkig.........SpeakdLikklLvkdPe
                   ly+l+ G  PF++++++++ k+i ++ +++++++++a+ Li+ lL ++P+
   mKIAA4088   265 LYILVHGTMPFDgqDHKTLVKQISngayreppkPSDACGLIRWLLMVNPT 314  

                   kRlta.eaLedeldikaHPff<-*
                   +R t +++         H ++   
   mKIAA4088   315 RRATLeDVAS-------HWWV    328  

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