hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj01350/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA4080  ( 1323 res)   mfj01350

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    187.6    1.2e-51   1
DnaJ     DnaJ molecular chaperone homology domain        29.7    0.00041   1
TyrKc    Tyrosine kinase, catalytic domain              -24.8    1.3e-09   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TyrKc      1/1      58   331 ..     1   280 []   -24.8  1.3e-09
S_TKc      1/1      58   335 ..     1   231 []   187.6  1.2e-51
DnaJ       1/1    1258  1319 ..     1    72 []    29.7  0.00041

Alignments of top-scoring domains:
TyrKc: domain 1 of 1, from 58 to 331: score -24.8, E = 1.3e-09
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda...keeFlrEa
                      l+  ++L eG F  Vy+++  ++++e A K L ++ +++ +++++E 
   mKIAA4080    58    LRVRRVLAEGGFAFVYEAQDLgsgREYALKRLLSNEeekNRAIIQEV 104  

                   kiMkklGgkHpNiVkLlGvcteegrr....FmevePlmivmEymegGdLl
                     +kkl   HpNiV++  +++ +++ ++++       ++++E+++ G L 
   mKIAA4080   105 CFLKKL-SGHPNIVQFCSAASIGKEEsdtgQ---AEFLLLTELCK-GQLV 149  

                   dyLrknrpk..lslsdLlsfAlQIAkGMeYLesk..nfvHRDLAARNcLv
                   ++L++ + k++ls +  l++ +Q ++  ++ ++++++++HRDL   N L+
   mKIAA4080   150 EFLKRVECKgpLSCDSILKIFYQTCRAVQHMHRQkpPIIHRDLKVENLLL 199  

                   genkvvKIsDFGLsRdlyddDkkG...........eskdyYrkkggkggk
                   ++++++K +DFG +  + ++    + + + +++  ++++  r ++    +
   mKIAA4080   200 SNQGTIKLCDFGSATTISHY---PdyswsaqkramVEEEITRNTT-PMYR 245  

                   tllPirWmAPEsl.kdgkF..tskSDVWSFGVlLWEiftlGeqPYpgeiq
                   t        PE  + ++ F+  +k D+W+ G  L+ ++ + + P ++   
   mKIAA4080   246 T--------PEIVdLYSNFpiGEKQDIWALGCILY-LLCFRQHPFED--- 283  

                   qfmsneevleylkkGyRlpkPendlpiSsvtCPdelYd.lMlqCWaedPe
                          +  ++ +G++  +  +            ++ +l++   + +Pe
   mKIAA4080   284 ------GAKLRIVNGKYSIPVND--------TRYTVFHdLIRAMLKVNPE 319  

                   dRPtFselverl<-*
                   +R + +e+v++l   
   mKIAA4080   320 ERLSIAEVVRQL    331  

S_TKc: domain 1 of 1, from 58 to 335: score 187.6, E = 1.2e-51
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik.......erilrEi
                       ++ ++l +G+F+ Vy a+d ++gr++A+K++ ++++++++ i++E+
   mKIAA4080    58    LRVRRVLAEGGFAFVYEAQDLGSGREYALKRLLsneeeknRAIIQEV 104  

                   kiLkk..dHPNIVkLydvfed.........dklylVmEyceGdlGdLfdl
                     Lkk ++HPNIV++  +   +++++++++ ++ l +E+c G    L ++
   mKIAA4080   105 CFLKKlsGHPNIVQFCSAASIgkeesdtgqAEFLLLTELCKG---QLVEF 151  

                   lkkrgrrglrkvlsE.earfyfrQilsaLeYLHsq..gIiHRDLKPeNiL
                   lk+  ++g+   ls + + ++f+Q+++a++++H+q++ IiHRDLK eN+L
   mKIAA4080   152 LKRVECKGP---LSCdSILKIFYQTCRAVQHMHRQkpPIIHRDLKVENLL 198  

                   Lds..hvKlaDFGlArql...................ttfvGTpeYmAPE
                   L++++++Kl+DFG+A+ +++ ++ + + +++   +++ t   Tp Y+ PE
   mKIAA4080   199 LSNqgTIKLCDFGSATTIshypdyswsaqkramveeeITRNTTPMYRTPE 248  

                   vl......gYgkpavDiWSlGcilyElltGkpPFp..qldlifkkig...
                   +++  ++ + g  + DiW+lGcily l+ ++ PF+++   +i +   + +
   mKIAA4080   249 IVdlysnfPIGE-KQDIWALGCILYLLCFRQHPFEdgAKLRIVNGKYsip 297  

                   .....SpeakdLikklLvkdPekRlta.eaLedeldikaHPff<-*
                    ++++   + dLi+ +L+++Pe+Rl++ e+ +      + +     
   mKIAA4080   298 vndtrYTVFHDLIRAMLKVNPEERLSIaEVVR-----QLQEIA    335  

DnaJ: domain 1 of 1, from 1258 to 1319: score 29.7, E = 0.00041
                   *->tdyYeiLGvskdAsddeIKKAYRkLAlkyHPDKnpgdpelseeklpe
                      +  +         +++++KK+YR+ +l +HPDK +g p         
   mKIAA4080  1258    ESRWTPVSMADLVTPEQVKKQYRRAVLVVHPDKATGQPY-------- 1296 

                   eekeeAeekFkeIneAYevLsDpek<-*
                     ++ A+  F+e+n A++   ++ +   
   mKIAA4080  1297 --EQYAKMIFMELNDAWSEFENQGS    1319 

//