hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mic/mic12051/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4058  ( 832 res)   mic12051

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
Kinesin  Kinesin motor domain                           576.8   1.3e-169   1
CHASE3   CHASE3 domain                                  -29.7       0.81   1
GBP_C    Guanylate-binding protein, C-terminal domain  -154.1       0.98   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
CHASE3     1/1     143   269 ..     1   142 []   -29.7     0.81
Kinesin    1/1      52   404 ..     1   424 []   576.8 1.3e-169
GBP_C      1/1     307   567 ..     1   305 []  -154.1     0.98

Alignments of top-scoring domains:
CHASE3: domain 1 of 1, from 143 to 269: score -29.7, E = 0.81
                   *->aaaqwvs.htqevlaal.dellallldaEsgqmRGYLLTgddeyLdp
                       + +wv+++ ++v+ ++ + + +++++  ++q   YL+  +  yL+ 
   mKIAA4058   143    MQGTWVEpELRGVIPNAfEHIFTHISRSQNQQ---YLV--RASYLEI 184  

                   YeqAkpeldqalarLraLtvDNPqqqkrldrlealieekldeaeetldla
                   Y++ ++ l+ +    r  ++ NP+   ++++l++ ++  ++e+e++++l 
   mKIAA4058   185 YQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVKEIEHVMNL- 233  

                   reraggleaavalvrsdrGKtlmdeiRelldqmreeEerlLaqrnaa<-*
                     ++++  +av +       t m+e  + + ++     +  ++ +     
   mKIAA4058   234 --GNQA--RAVGS-------THMNEVSSRSHAIFVITVECSERGSDG    269  

Kinesin: domain 1 of 1, from 52 to 404: score 576.8, E = 1.3e-169
                   *->RvRPlnerEksrgs.vvvnv.....sedvessrltn.gkkktFtFDk
                      R+RPl+ +E+++g++++++++ + + ++ ++ r  +++ +ktFtFD+
   mKIAA4058    52    RCRPLSRKEEAAGHeQILTMdvklgQVTLRNPRAAPgELPKTFTFDA 98   

                   VFdpeatQegssepYAsqefvyesvakPlvesvleGyNgtiFAYGQTGSG
                   V+d ++           q+++y+++++Pl++svl+G+Ngt+FAYGQTG+G
   mKIAA4058    99 VYDASSK----------QADLYDETVRPLIDSVLQGFNGTVFAYGQTGTG 138  

                   KTYTMeGppesdkesgnptddsytlpeeepGiiPRaledlFerieerker
                   KTYTM+G+      ++         ++e +G+iP a+e++F++i++ +  
   mKIAA4058   139 KTYTMQGT------WV---------EPELRGVIPNAFEHIFTHISRSQ-- 171  

                   kpvfKPklnekgwellnsqetligvsfdrglssdlyvndlefsvkvSylE
                                                         + +++v++SylE
   mKIAA4058   172 --------------------------------------NQQYLVRASYLE 183  

                   IYNEkirDLLspsppqrgspskanekkkkkpLrireDpkrGgkmdgvyVe
                   IY+E+irDLLs++p            +k+  L+++e+p++G     vy++
   mKIAA4058   184 IYQEEIRDLLSKEP------------GKR--LELKENPETG-----VYIK 214  

                   GLteveVssaeevlelLelGnknRtvasTkmNerSSRSHaiFtitveqrn
                   +L++++ +++ e+ ++++lGn+ R+v+sT+mNe SSRSHaiF itve ++
   mKIAA4058   215 DLSSFVTKNVKEIEHVMNLGNQARAVGSTHMNEVSSRSHAIFVITVECSE 264  

                   tdstgsvvtgkdnsgeesvrvskLnLVDLAGSERaskTgatg........
                   ++s+g+          +++rv+kLnLVDLAGSER+ k+g  + +++ +++
   mKIAA4058   265 RGSDGQ----------DHIRVGKLNLVDLAGSERQNKAGPNAaggpatqp 304  

                   ...............AggrRLkEaanINkSLsaLGnVInALadkqkssHi
                   + ++++++++ +++ ++g+R kEa++IN SLsaLGnVI+ALa + +s+Hi
   mKIAA4058   305 tagggsgsgsasgsaSSGERPKEASKINLSLSALGNVIAALAGN-RSTHI 353  

                   PYRDSKLTrLLqDSLGGGDNsKTlMIaniSPsssrNntnyeETLsTLrFA
                   PYRDSKLTrLLqDSLGG  N+KT+M+a+  P+s+    +y+E+LsTLrFA
   mKIAA4058   354 PYRDSKLTRLLQDSLGG--NAKTIMVATLGPASH----SYDESLSTLRFA 397  

                   sRAKnIk<-*
                   +RAKnIk   
   mKIAA4058   398 NRAKNIK    404  

GBP_C: domain 1 of 1, from 307 to 567: score -154.1, E = 0.98
                   *->GGiiVTGprLatLVqtYvnAInSGsVPClesav.tTLAQiENsaAVq
                      GG    G++ ++         +SG+ P+  s  ++ L  + N +A  
   mKIAA4058   307    GGGSGSGSASGS--------ASSGERPKEASKInLSLSALGNVIA-- 343  

                   kAiahYeeqMeQrleLP.TetlQeLLdvHrdCEkEAlavFmenSFkNVDv
                    A a      ++  + P  ++   L  +  d+        m    +    
   mKIAA4058   344 -ALAG-----NRSTHIPyRDS--KLTRLLQDSLGGNAKTIMVATLG--PA 383  

                   kQkFqrkLvaqLeaakedFcrkNeeaSssrCqalLedLskdLeelikqGd
                    + + + L ++L+ a+ +   kN+                 + e++k   
   mKIAA4058   384 SHSYDESL-STLRFANRAKNIKNKP---------------RVNEDPKD-- 415  

                   fsvpGGhrLfleavqeieakYkQvPrKGvkAsevLkefLqDILVHskedl
                           L+ e  +ei     Q   KG   +   +++ +     +k  +
   mKIAA4058   416 -------TLLREFQEEIARLKAQLEKKGMLGKRPRRKSSR-----RKKAV 453  

                   aDsLlqtdqaLtlkekaiEaerN.........ikkEaAEkaekllrEkQK
                          + +  ++  a E+  N+++++++++i+  a+Ek  +   ++QK
   mKIAA4058   454 SAPAGYPEGSVIEAWVAEEEDDNnnnhhppqpILEAALEKNMENYLQDQK 503  

                   rhEeamEakEksyqEhkkqLtek...mEserkqLmaEqnrmLEhklkeqe
                   +          + +E k+ ++ +++    e+ +L++E ++mLE ++ eq 
   mKIAA4058   504 E----------RLEEEKAAIQDDrslVSEEKQKLLEEKEKMLEDLRREQQ 543  

                   ..eLleeGFknestllekeIselr<-*
                    +eLl  ++k     l  + +++    
   mKIAA4058   544 atELLAAKYKAMESKLLIGGRNIM    567  

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