hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg07434/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4053  ( 1400 res)   mbg07434

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
TIG      IPT/TIG domain                                 265.8    5.6e-76   4
PSI      Plexin repeat                                  150.4    3.1e-41   3

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PSI        1/3      18    68 ..     1    63 []    62.9  6.9e-15
PSI        2/3     164   211 ..     1    63 []    47.9  2.2e-10
PSI        3/3     312   366 ..     1    63 []    56.6  5.5e-13
TIG        1/4     368   463 ..     1   105 []    71.1  2.3e-17
TIG        2/4     465   549 ..     1   105 []    88.8  1.1e-22
TIG        3/4     552   651 ..     1   105 []    71.3  2.1e-17
TIG        4/4     654   740 ..     1   105 []    41.4    2e-08

Alignments of top-scoring domains:
PSI: domain 1 of 3, from 18 to 68: score 62.9, E = 6.9e-15
                   *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfyGeCprae.
                      +C qytsC  CL++rdp +CgWC++++ C+r++        C+rae+
   mKIAA4053    18    SCVQYTSCELCLGSRDP-HCGWCVLHSICSRQD-------ACERAEe 56   

                   pendqwldwswssskCp<-*
                   p      +++++  +C+   
   mKIAA4053    57 PQ-----RFASDLLQCV    68   

PSI: domain 2 of 3, from 164 to 211: score 47.9, E = 2.2e-10
                   *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfyGeCpraep
                      nCs+++sC +C++ +    C+WC++++ Ct ++a      +C   e 
   mKIAA4053   164    NCSVHQSCLACVNGSF--PCHWCKYRHVCTNNAA------DCAFLE- 201  

                   endqwldwswssskCp<-*
                         +++++s++Cp   
   mKIAA4053   202 ------GRVNMSEDCP    211  

PSI: domain 3 of 3, from 312 to 366: score 56.6, E = 5.5e-13
                   *->nCsqy.tsCssCLaardpfyCgWCssegrCtrgsaytsfyGeCprae
                      +C ++++sC+ CL a++ f+CgWC+ e+rC++++       +Cp ++
   mKIAA4053   312    KCPALrQSCGLCLKADPRFECGWCVAERRCSLRH-------HCPADS 351  

                   .pendqwldwswssskCp<-*
                   +++   w+++ + ss+C+   
   mKIAA4053   352 pAS---WMHAHHGSSRCT    366  

TIG: domain 1 of 4, from 368 to 463: score 71.1, E = 2.3e-17
                   *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt
                      P+I ++sP++gp  GGt++TitG+nlg          +fed ++ V 
   mKIAA4053   368    PKILKLSPETGPRQGGTRLTITGENLG---------LRFEDVRLGVH 405  

                   fggtpvpCdvisssss..tqivCktPpva.ggpsppvvtvsvdggg.sgd
                   +g +   C ++ s++++ +qivC+++ +++ +       v+v + + s  
   mKIAA4053   406 VGKVL--CSPVESEYIsaEQIVCEIGDAStLRAHD--ALVEVCVRDcSLH 451  

                   grssspvtFtYv<-*
                   +r  sp++Ft+v   
   mKIAA4053   452 YRALSPKRFTFV    463  

TIG: domain 2 of 4, from 465 to 549: score 88.8, E = 1.1e-22
                   *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt
                      P+++++sPs+gplsGGt+i i Gs+l++gs            d+ V+
   mKIAA4053   465    PTFYRVSPSRGPLSGGTWIGIEGSHLNAGS------------DVAVS 499  

                   fggtpvpCdvissssstqivCktPpva.ggpsppvvtvsvdgggsgdgrs
                   +gg+p  C + +++s  +i+C tPp++++g +p  + + +++++    +s
   mKIAA4053   500 IGGRP--CSFSWRNS-REIRCLTPPGHtPGSAP--IVININRAQ----LS 540  

                   sspvtFtYv<-*
                     +v ++Y+   
   mKIAA4053   541 NPEVKYNYT    549  

TIG: domain 3 of 4, from 552 to 651: score 71.3, E = 2.1e-17
                   *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt
                      P+I +i P+++  sGGt +T+tG+nl ++ ePrir           +
   mKIAA4053   552    PTILRIDPEWSINSGGTLLTVTGTNLATVREPRIR----------AK 588  

                   fggtpv..pCdvissssstqivCktPpva.ggpsppv.......vtvsvd
                   +gg++ +++C+v +++    +vC+ P+  ++  spp+ +++++++ + +d
   mKIAA4053   589 YGGIERenSCMVYNDTT---MVCRAPSIDnPKRSPPElgerpdeIGFIMD 635  

                   gggsgdgrssspvtFtYv<-*
                   +++   +++ ++ +F Y+   
   mKIAA4053   636 NVR--TLLVLNSSSFLYY    651  

TIG: domain 4 of 4, from 654 to 740: score 41.4, E = 2e-08
                   *->PvItsisP.ssgplsGGteiTitGsnlgsgsePrirk.ntfededik
                      Pv + +sP+    l++ + ++++G+nl  ++ ++ r+++t       
   mKIAA4053   654    PVLEPLSPtGLLELKPSSPLILKGRNLLPPAPGNSRLnYT------- 693  

                   VtfggtpvpCdvissssstqivCktPpva.ggpsppvvtvsvdgggsgdg
                   V++g+tp  C +++s+  tq+ C+ P+++++++    vtv  +g +    
   mKIAA4053   694 VLIGSTP--CILTVSE--TQLLCEAPNLTgQHK----VTVRAGGFE---- 731  

                   rssspvtFtYv<-*
                      sp+  +++   
   mKIAA4053   732 --FSPGMLQVY    740  

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