hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg11557/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4052  ( 1046 res)   mbg11557

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RasGEF   Guanine nucleotide exchange factor for Ras-l   304.2    9.3e-87   1
RA       Ras association (RalGDS/AF-6) domain            83.5    2.6e-20   1
PDZ      Domain present in PSD-95, Dlg, and ZO-1/2.      67.2    2.1e-15   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PDZ        1/1      76   148 ..     1    80 []    67.2  2.1e-15
RA         1/1     285   371 ..     1   102 []    83.5  2.6e-20
RasGEF     1/1     392   631 ..     1   261 []   304.2  9.3e-87

Alignments of top-scoring domains:
PDZ: domain 1 of 1, from 76 to 148: score 67.2, E = 2.1e-15
                   *->gglGfsivg......gifvssvvpGspAakaGrkslglLkvGDvIle
                       +l f ++g+++++ g+fv +v+ Gs Aa aG      Lk GD+++e
   mKIAA4052    76    SPLHFCLTGgsekgfGVFVEEVESGSKAADAG------LKRGDQVME 116  

                   VNGetsvegltheeavdllkkaggggvGekvtLtvlRgg<-*
                   VNG ++ e+ t + a+++l++      ++++ Ltv+ +    
   mKIAA4052   117 VNG-QNFENITLAKALEILRN------NTHLALTVKTNI    148  

RA: domain 1 of 1, from 285 to 371: score 83.5, E = 2.6e-20
                   *->dtyvlrVyvddlsavdpgqtyktlrvskrtTardViqqllekfhltd
                        +v+rV+ +d       q+++++ +sk+tTa++V++q++++f+lt+
   mKIAA4052   285    PDQVIRVFKAD-------QQSCYIIISKDTTAKEVVCQAVQEFGLTG 324  

                   edpeeYvLvevlpsggkErvLlddenPlqlqklwprdaksprqsslrFvL
                     +++Y+L+ev+  +  E v++++++P q  kl+ r+     q + r++L
   mKIAA4052   325 -ASDTYSLCEVS--VTPEGVIKQRRLPDQFSKLADRI-----QLNGRYYL 366  

                   rkrdd<-*
                   ++++    
   mKIAA4052   367 KNNME    371  

RasGEF: domain 1 of 1, from 392 to 631: score 304.2, E = 9.3e-87
                   *->lllldpeelAeQLTlldfelFrkIepsEllgsvwgkrskkspsplap
                       l+l++ e+A+QL+++df lFr+Iep+E+++ +++ +sk ++++   
   mKIAA4052   392    MLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTH--- 435  

                   qnleafierfNevsnwVateIlkqttlkpkkRaevlskFIkVAkhcreLn
                     l++f    N+ ++wVa+eIl++ +    kR++++++FIk+A hcre++
   mKIAA4052   436 --LKQFEDIVNQETFWVASEILSESN--QLKRMKIIKHFIKIALHCRECK 481  

                   NFnSlmAIvsaLssspIsRLkkTWeklsskykklfeeLeelldpserNfk
                   NFnS++AI+s+L+ +p+ RL+ TWekl+sky+k +++L++l+dps rN+ 
   mKIAA4052   482 NFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPS-RNMA 530  

                   nYReaLkscnkspnvqppcvPflGvyLkDLtfidegnpdflengtkglvN
                   +YR+ L+s       qpp++P ++v  kD+tf++egn+  ++    glvN
   mKIAA4052   531 KYRNILSSQSM----QPPIIPLFPVVKKDMTFLHEGNDSKVD----GLVN 572  

                   FeKrrkiakilreirqlqsacqpynlkpnrndiqellrasrplevlpeee
                   FeK+r+iak +r+i++++s  +++++++++++ ++ +r+   l++l++  
   mKIAA4052   573 FEKLRMIAKEIRHIIRMTS--ANMDPAMMFRQRKKRWRS---LGSLSQGS 617  

                   delyelSlriEPrv<-*
                    +++ l  +        
   mKIAA4052   618 TNSNMLDVQGGAHK    631  

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