hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg11557/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4052  ( 1046 res)   mbg11557

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RasGEF   RasGEF domain                                  175.6    7.9e-49   1
RA       Ras association (RalGDS/AF-6) domain            82.4    9.5e-21   1
PDZ      PDZ domain (Also known as DHR or GLGF)          65.5    1.1e-15   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PDZ        1/1      66   145 ..     1    82 []    65.5  1.1e-15
RA         1/1     285   371 ..     1    98 []    82.4  9.5e-21
RasGEF     1/1     393   578 ..     1   227 []   175.6  7.9e-49

Alignments of top-scoring domains:
PDZ: domain 1 of 1, from 66 to 145: score 65.5, E = 1.1e-15
                   *->evtlekevkrgglGfsikggsdk..givvsevlpGsgaAeagGrLke
                      +v+l+k    ++l f + ggs+k+ g++v ev  Gs aA+ag  Lk 
   mKIAA4052    66    QVVLQKASRESPLHFCLTGGSEKgfGVFVEEVESGSKAADAG--LKR 110  

                   GDqIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                   GDq+++vNGq++en+++++a ++l++    +++Lt++   
   mKIAA4052   111 GDQVMEVNGQNFENITLAKALEILRNNT--HLALTVK    145  

RA: domain 1 of 1, from 285 to 371: score 82.4, E = 9.5e-21
                   *->dsgvlrVygedgtpgtyktilvskntTaeeViralLrKfgldaddpe
                       + v+rV++ d++   ++ i +sk+tTa+eV++++++ fgl +  ++
   mKIAA4052   285    PDQVIRVFKADQQ---SCYIIISKDTTAKEVVCQAVQEFGL-TGASD 327  

                   dyvLvEvslvlerggeerrvLpddEkPlqiqlqlkrdaqvrsrFlLrrre
                    y+L+Evs+  e  +++r +Lpd+   l  + ql      ++r++L+++ 
   mKIAA4052   328 TYSLCEVSVTPEGVIKQR-RLPDQFSKLADRIQL------NGRYYLKNNM 370  

                   d<-*
                   +   
   mKIAA4052   371 E    371  

RasGEF: domain 1 of 1, from 393 to 578: score 175.6, E = 7.9e-49
                   *->LllDplelAkQLTLlEhelfkkItpfefLgsKmKHEGPqvWgkksfk
                      L l+  e+A+QL  ++++lf++I+p e  +         + +  s++
   mKIAA4052   393    LQLSTIEVATQLSMRDFDLFRNIEPTEYID--------DLFKLDSKT 431  

                   gkeerspnidktiknfNqltnfvsetIlkqeFPTNPEFSKkvdpkkRaev
                   g+      + ++    Nq t +v+++Il++            +  kR+++
   mKIAA4052   432 GNT----HLKQFEDIVNQETFWVASEILSES-----------NQLKRMKI 466  

                   iqkfIqVAdhcReLnNFnSllaIisALysspIyRLkkTWekvppqslklI
                   i++fI +A hcRe +NFnS++aIis+L+ +p+ RL+ TWek+p+++ k  
   mKIAA4052   467 IKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKH- 515  

                   feeLnkLmdsdrNfsnyRelLksigplappnLdddfvraPCVPFfGvYLs
                   +++L+ L+d++rN  +yR+ L+s +            + P +P f+v  +
   mKIAA4052   516 LQDLQDLFDPSRNMAKYRNILSSQSM-----------QPPIIPLFPVVKK 554  

                   DLtfleeGnpdyleekKINtnlvNFsKrrk<-*
                   D tfl+eGn+++        +lvNF+K r+   
   mKIAA4052   555 DMTFLHEGNDSKVD------GLVNFEKLRM    578  

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