hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm11085/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4047  ( 1506 res)   mpm11085

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
CUT      CUT domain                                     558.6   4.1e-164   3
Homeobox Homeobox domain                                 73.5    4.4e-18   1
Filament Intermediate filament protein                 -188.8       0.58   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Filament   1/1      38   347 ..     1   359 []  -188.8     0.58
CUT        1/3     553   640 ..     1    88 []   185.8  6.9e-52
CUT        2/3     920  1007 ..     1    88 []   191.9    1e-53
CUT        3/3    1103  1190 ..     1    88 []   188.6  9.9e-53
Homeobox   1/1    1231  1287 ..     1    57 []    73.5  4.4e-18

Alignments of top-scoring domains:
Filament: domain 1 of 1, from 38 to 347: score -188.8, E = 0.58
                   *->nEKeqmQnLNDRLAsYIdKVRfLEqqNkeLevkieelrqkqsrg.gp
                                          +  Eq  k+L  + +e +  +++  + 
   mKIAA4047    38    --------------------DESEQSRKRLIEQSREFKKNTPEDlRK 64   

                   asvsrlyslYeteieeLRrqidqltner......................
                   + v++l   ++ ei+ L +   +++++  +  ++  + +++ +  + +++
   mKIAA4047    65 Q-VAPLLKSFQGEIDALSKRSKEAEAAFltvykrlidvpdpvpaldvgqq 113  

                   ........arlqlEidnlrealedfrkKyed...Ke.DL.aaQnqlkdlE
                    + + ++  +++ E  +lre le+++k++ + ++ e  ++a+  +++++E
   mKIAA4047   114 leikvqrlHDIETENQKLRETLEEYNKEFAEvknQEvTIkALKEKIREYE 163  

                   ialntkeaeLaTaLeRqeaEndlvgLRaQiAklEslaaRkdlDeaTLarv
                   + l  + ae   ++  q++ nd++               + l+e  ++ +
   mKIAA4047   164 QTL-KSQAETIALEKEQKLQNDFAEK------------ERKLQETQMSTT 200  

                   ....DLEnkvEsLqEElaFLKknHeEEvkeLqaqiqdtgqvnVEmDaarq
                   ++ +++E k+++Lq  l+  +     E+ +L+    +   +++  D+   
   mKIAA4047   201 skleEAEHKLQTLQTALEKTRT----ELFDLKTKYDEE--TTAKADE--- 241  

                   qEwklDLtkaLrEiRaQYEeiAeknrqeaEewYksKleeLqtaaarngea
                                        +e+ + ++E   +++ e +q +a++  e+
   mKIAA4047   242 ---------------------IEMIMTDLERA-NQRAEVAQREAETLREQ 269  

                   lrsaKeEitElRRqiQ.sLeiELqslksqnasLErqlaElEeryeaelaq
                   l+sa + + +l  qiQ++    ++ l  +++sLE +la      e+e aq
   mKIAA4047   270 LSSANHSL-QLASQIQkAPDVAIEVL--TRSSLEVELA----AKEREIAQ 312  

                   yqalisqlEeeLqqlreEMarqLrEYQeLLdVKlaLDiEIATYRKLLEGE
                   + +  ++l++ L++lre  a q  ++++ L++K                 
   mKIAA4047   313 LVEDVQRLQASLTKLRENSASQISQLEQQLNAK----------------- 345  

                   EsR<-*
                    +    
   mKIAA4047   346 -NS    347  

CUT: domain 1 of 3, from 553 to 640: score 185.8, E = 6.9e-52
                   *->nqqigmneelDTaeIarrvkeeLkrhnIgQriFAekvLGlSQGslSd
                      +++i+++ee+DTaeIar+vke+L++hnIgQriF+++vLGlSQGs+S+
   mKIAA4047   553    AGSISEGEEIDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSE 599  

                   LLrkPKPWskLtqkGREpFrRMqnWLsdpnavrdlilqqek<-*
                   +L++PKPW+kLt++G+EpF++M+++Lsd++++ +l+++q++   
   mKIAA4047   600 ILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGR    640  

CUT: domain 2 of 3, from 920 to 1007: score 191.9, E = 1e-53
                   *->nqqigmneelDTaeIarrvkeeLkrhnIgQriFAekvLGlSQGslSd
                      +++++m++e+DT+e++r+vke+L++++I+QriF+ekvLGlSQGs+Sd
   mKIAA4047   920    QYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSD 966  

                   LLrkPKPWskLtqkGREpFrRMqnWLsdpnavrdlilqqek<-*
                   +L++PKPWskLtqkGREpF+RMq+WL++++ + +l++q ++   
   mKIAA4047   967 MLSRPKPWSKLTQKGREPFIRMQLWLNGELGQGVLPVQGQQ    1007 

CUT: domain 3 of 3, from 1103 to 1190: score 188.6, E = 9.9e-53
                   *->nqqigmneelDTaeIarrvkeeLkrhnIgQriFAekvLGlSQGslSd
                      ++ ++m++elDT+ I++rvke L+++n gQr+F+e++LGl+QGs+Sd
   mKIAA4047  1103    QELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSD 1149 

                   LLrkPKPWskLtqkGREpFrRMqnWLsdpnavrdlilqqek<-*
                   LL++PKPW+kL+ kGREpF+RMq+WL+dpn+v++l++++++   
   mKIAA4047  1150 LLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRM    1190 

Homeobox: domain 1 of 1, from 1231 to 1287: score 73.5, E = 4.4e-18
                   *->rrkRTtftpeQleeLEkeFqknrYPsreeReeLAkkLgLterqVkvW
                      +++R++  pe  e+L++++q+ +YPs++++eeLA +L+L  + V +W
   mKIAA4047  1231    KKPRVVLAPEEKEALKRAYQQKPYPSPKTIEELATQLNLKTSTVINW 1277 

                   FQNRRaKwKk<-*
                   F+N R + ++   
   mKIAA4047  1278 FHNYRSRIRR    1287 

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