hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpg/mpg00417/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4032  ( 749 res)   mpg00417

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N 
--------      -----------                               -----    ------- ---
Fzo_mitofusin fzo-like conserved region                 390.7   1.4e-113   1
Dynamin_N     Dynamin family                            102.8    6.6e-27   1
MMR_HSR1      GTPase of unknown function                  3.7     0.0031   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
Dynamin_N       1/1      86   246 ..     1   217 []   102.8  6.6e-27
MMR_HSR1        1/1      84   248 ..     1   140 []     3.7   0.0031
Fzo_mitofusin   1/1     575   745 ..     1   171 []   390.7 1.4e-113

Alignments of top-scoring domains:
Dynamin_N: domain 1 of 1, from 86 to 246: score 102.8, E = 6.6e-27
                   *->IaVvGdqSsGKSSvLnaLlGrdfnLPhrgpgEptTrrplvTlqlges
                      +a++G  SsGKSSv+na+l   + LP +g+g +tT ++l  ++  + 
   mKIAA4032    86    VAFFGRTSSGKSSVINAMLWDKV-LP-SGIG-HTTNCFLS-VEGTDG 128  

                   peaieivsipgavkveykdflhplkkfedfsevreeieketdriagknkg
                    +        +++  e  d+   +k  +  +++++++ +  d +ag +++
   mKIAA4032   129 DK--------AYLMTEGSDE---KKSVKTVNQLAHALHMDKDLKAGCLVH 167  

                   isseGalakvsfgavkyCnfskpiileilsplvpgltLVDtPGldslSva
                   +                      +    +++l+++l+LVD+PG d   + 
   mKIAA4032   168 V---------------------FWPKAKCALLRDDLVLVDSPGTDV--TT 194  

                   vgdqqPeDieeqIrelteeyiskpadiILaVvpAnvaLdlstssdealfl
                   + d            ++++++   ad++++V ++ +   l ++  e+ f 
   mKIAA4032   195 ELD-----------IWIDKFC-LDADVFVLVANSES--TLMNT--EKHFF 228  

                   arevdpkgerdktigVltKd<-*
                    +  +   +    i++l++    
   mKIAA4032   229 HKVNERLSKP--NIFILNNR    246  

MMR_HSR1: domain 1 of 1, from 84 to 248: score 3.7, E = 0.0031
                   *->lrvaivGrPNVGKSTLiNaLtgkkraiVsdyPGtTrdpnegrvel..
                      ++va+ Gr+ +GKS+ iNa++  +++  s +  tT       + +++
   mKIAA4032    84    MKVAFFGRTSSGKSSVINAMLW-DKVLPSGIGHTTNC----FLSVeg 125  

                   ..................................................
                   +++++    +++++++++ ++ ++  +  + +++ + +   +   ++ + 
   mKIAA4032   126 tdgdkaylmtegsdekksvktvnqlahalhmdkdlkagclvhvfwpkakc 175  

                   ..dgrqiilvDTPGiiegaskgegelgertleaieeaDlilfVvDasegl
                       ++++lvD PG   +   +         +   +aD+ ++V ++   l
   mKIAA4032   176 alLRDDLVLVDSPGTDVTTELDIW-----IDKFCLDADVFVLVANSESTL 220  

                   tedytieeDleiadllydeerernleltLqelekkgkPvilvlNKiD<-*
                         + +++++ ++    +           ++++  ++++ N +D   
   mKIAA4032   221 M-----NTEKHFFHKV----N----------ERLSKPNIFILNNRWD    248  

Fzo_mitofusin: domain 1 of 1, from 575 to 745: score 390.7, E = 1.4e-113
                   *->lpPlvsgnseqqemmislVtglASvtSrGSlGilvVgGvvwKavGWr
                        P++++n+ q+e+mi+l+tglAS+tSr+S+Gi+vVgGv+wK+vGW+
   mKIAA4032   575    SNPAAPDNAAQEELMITLITGLASLTSRTSMGIIVVGGVIWKTVGWK 621  

                   viavsgaLYGsLYlYERlsWTtaAKERaFKsQFvrhatekLrmvvsaTss
                   +i+v + +YG+LYlYERl+WTt AKERaFK+QFv++atekL+m+vs Ts+
   mKIAA4032   622 LISVTLSMYGALYLYERLTWTTRAKERAFKQQFVNYATEKLQMIVSFTSA 671  

                   nCshQvqQeLattFarLcaqVdetlrdLnnelaeLkkqIdaleslQkslK
                   nCshQvqQe+attFarLc+qVd+t++ L++e+a+L k+Id+le++Q+++K
   mKIAA4032   672 NCSHQVQQEMATTFARLCQQVDVTQKHLEEEIARLSKEIDQLEKIQNNSK 721  

                   lLRnKAvfLaseLeqFthqYLrss<-*
                   lLRnKA +L+seLe+F +q+L +s   
   mKIAA4032   722 LLRNKAIQLESELENFSKQFLHPS    745  

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