hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg12171/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4026  ( 986 res)   mbg12171

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    319.6    2.2e-91   1
TyrKc    Tyrosine kinase, catalytic domain               63.5    4.6e-15   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
S_TKc      1/1      56   314 ..     1   231 []   319.6  2.2e-91
TyrKc      1/1      56   317 ..     1   280 []    63.5  4.6e-15

Alignments of top-scoring domains:
S_TKc: domain 1 of 1, from 56 to 314: score 319.6, E = 2.2e-91
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik.......erilrEi
                      +e++ +lG GaFGkVy+a++k+tg l A Kvi ++++++ e+ + Ei
   mKIAA4026    56    WEIVGELGDGAFGKVYKAKNKETGALAAAKVIEtkseeelEDYIVEI 102  

                   kiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgrrgl
                   +iL   dHP+IVkL+++++ ++kl++  E+c+G  G +  ++ +  r+  
   mKIAA4026   103 EILATcDHPYIVKLLGAYYYdGKLWIMIEFCPG--GAVDAIMLELDRG-- 148  

                   rkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvKlaD
                      l+E++++ ++rQ+l+aL++LH ++IiHRDLK  N+L++ ++ + laD
   mKIAA4026   149 ---LTEpQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLegDIRLAD 195  

                   FGlArql.......ttfvGTpeYmAPEvl........gYgkpavDiWSlG
                   FG++++  ++ +++++f+GTp++mAPEv+  ++ ++ +Y++ ++DiWSlG
   mKIAA4026   196 FGVSAKNlktlqkrDSFIGTPYWMAPEVVlcetmkdaPYDY-KADIWSLG 244  

                   cilyElltGkpPFp...qldlifkkig............SpeakdLikkl
                   ++l+E++  +pP ++ + + +++k+ ++++++  +++++S e++d++k  
   mKIAA4026   245 ITLIEMAQIEPPHHelnPMRVLLKIAKsdpptlltpskwSVEFRDFLKIA 294  

                   LvkdPekRlta.eaLedeldikaHPff<-*
                   L+k+Pe R++a ++L+       HPf+   
   mKIAA4026   295 LDKNPETRPSAaQLLQ-------HPFV    314  

TyrKc: domain 1 of 1, from 56 to 317: score 63.5, E = 4.6e-15
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda...keeFlrEa
                       +   +LG GaFG+Vyk++ k+++   A K++   +++++e+ + E+
   mKIAA4026    56    WEIVGELGDGAFGKVYKAKNKetgALAAAKVIETKSeeeLEDYIVEI 102  

                   kiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldyLr
                   +i+     +Hp iVkLlG+   +       + l+i  E+++gG+ +    
   mKIAA4026   103 EILATC--DHPYIVKLLGAYYYD-------GKLWIMIEFCPGGAVDAIML 143  

                   knrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenkvvKI
                   +  + l+ ++    + Q  +  ++L+ k+++HRDL A N+L + ++ ++ 
   mKIAA4026   144 ELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGDIRL 193  

                   sDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEsl.....k
                   +DFG s +             +r +   g+       WmAPE+   ++ k
   mKIAA4026   194 ADFGVSAKNLKT-------LQKRDSF-IGTP-----YWMAPEVVlcetmK 230  

                   dgkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGy.
                   d  +  k D+WS G++L E+    e+P+ +     +++ +vl ++ k ++
   mKIAA4026   231 DAPYDYKADIWSLGITLIEMA-QIEPPHHE-----LNPMRVLLKIAKSDp 274  

                   .RlpkPendlpiSsvtCPdelYdlMlqCWaedPedRPtFsel.....ver
                   + l  P           + e  d  +   + +Pe RP+ ++l +++ v+r
   mKIAA4026   275 pTLLTPSK--------WSVEFRDFLKIALDKNPETRPSAAQLlqhpfVSR 316  

                   l<-*
                       
   mKIAA4026   317 V    317  

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