hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg12171/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4026  ( 986 res)   mbg12171

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       294.1    1.7e-84   1
Pkinase_Tyr Protein tyrosine kinase                      92.1    1.1e-23   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase       1/1      56   314 ..     1   287 []   294.1  1.7e-84
Pkinase_Tyr   1/1      56   314 ..     1   272 []    92.1  1.1e-23

Alignments of top-scoring domains:
Pkinase: domain 1 of 1, from 56 to 314: score 294.1, E = 1.7e-84
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      +e+++ lG G+fG+Vykak+k tg + A K+i+ ++e++ +d++   
   mKIAA4026    56    WEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIV-- 100  

                   rsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrlldLfdylse
                     Ei+il+ ++Hp+Iv+l+++++++++l++  E+c+gG       +++  
   mKIAA4026   101 --EIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGG----AVDAIML- 143  

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldengv
                    + +++l  +e +++ +++Q+l++l++LH ++iiHRDLK  N+L+  +g+
   mKIAA4026   144 -ELDRGL--TEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGD 190  

                   vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvll....ggngyg
                   +    ++aDFG+++k  ++  ++ ++f GTp++mAPEv+l ++ ++ +y+
   mKIAA4026   191 I----RLADFGVSAKN-LkTLQkRDSFIGTPYWMAPEVVLcetmKDAPYD 235  

                   tkvDvWSlGvilyelltGkpPFsgevqds.ldqlqlirkilgpplefdsp
                   +k+D+WSlG++l+e++  +pP  +    ++ + l +i+k  +p l  +s 
   mKIAA4026   236 YKADIWSLGITLIEMAQIEPPHHEL---NpMRVLLKIAKSDPPTLLTPSK 282  

                   ewdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                   ++                e++d++k  L+k+P+ R++a+++lqHP++   
   mKIAA4026   283 WS---------------VEFRDFLKIALDKNPETRPSAAQLLQHPFV    314  

Pkinase_Tyr: domain 1 of 1, from 56 to 314: score 92.1, E = 1.1e-23
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtLkeigasseeie
                       ++  +LG GaFG+Vyk++ k    +t+   A K++ e + s+ee  
   mKIAA4026    56    WEIVGELGDGAFGKVYKAKNK----ETGALAAAKVI-E-TKSEEE-- 94   

                   redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL
                   +ed + E++i+ +  dHp iV+LlG+ +  ++     l+i  E+++gG  
   mKIAA4026    95 LEDYIVEIEILATC-DHPYIVKLLGAYYY-DGK----LWIMIEFCPGGAV 138  

                   ldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLVs
                   +  + +   +r Lt ++   +++Q  +++++L+ k+++HRDL A N+L +
   mKIAA4026   139 DAIMLEL--DRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMT 186  

                   enlvVKIsDFGLaRdiynddyY.vrkkgggk.lPvkWmAPEslkygk...
                    ++ ++ +DFG +       + ++ +k ++      WmAPE+      ++
   mKIAA4026   187 LEGDIRLADFGVSAK-----NLkTLQKRDSFiGTPYWMAPEVVLCETmkd 231  

                   ..FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyed.GyRLpr
                    ++  k D+WS G++L E+    e+P   ++ + +vl ++++++   L  
   mKIAA4026   232 apYDYKADIWSLGITLIEMAQ-IEPP-HHELNPMRVLLKIAKSdPPTLLT 279  

                   PenCPdelYdlMlqCWaedPedRPtFsel..verL<-*
                   P + + e  d  +   +++Pe RP+ ++l ++ +    
   mKIAA4026   280 PSKWSVEFRDFLKIALDKNPETRPSAAQLlqHPFV    314  

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