hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm01139/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4011  ( 876 res)   mpm01139

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
HECTc    Domain Homologous to E6-AP Carboxyl Terminus   608.8   1.9e-178   1
WW                                                      208.8      5e-58   4
C2       Protein kinase C conserved region 2 (CalB)      55.6    6.6e-12   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
C2         1/1      31   126 ..     1    92 []    55.6  6.6e-12
WW         1/4     300   332 ..     1    34 []    57.4  1.8e-12
WW         2/4     333   364 ..     1    34 []    49.0    6e-10
WW         3/4     412   444 ..     1    34 []    68.0  1.2e-15
WW         4/4     452   484 ..     1    34 []    51.5  1.1e-10
HECTc      1/1     540   876 .]     1   407 []   608.8 1.9e-178

Alignments of top-scoring domains:
C2: domain 1 of 1, from 31 to 126: score 55.6, E = 6.6e-12
                   *->tLtvkiisArnLp........DPYVkvs......kTkvvkktlsgfN
                      +L +++isA+   ++++  ++ PYV+v+ +++++kT+ + +t+   +
   mKIAA4011    31    QLQITVISAKLKEnkknwfgpSPYVEVTvdgqskKTEKCNNTN---S 74   

                   PvWnEesetFeFevpp.s.LeieVyDk......dfiGrvtippnnahqhs
                   P+W +    +++ v+p+s+L+++V+++ + +++ ++G++ ++        
   mKIAA4011    75 PKWKQ---PLTVIVTPtSkLCFRVWSHqtlksdVLLGTAGLD-------- 113  

                   adglihlsell.ggrh.kl<-*
                         + e l+++ ++ +   
   mKIAA4011   114 ------IYETLkSNNMkLE    126  

WW: domain 1 of 4, from 300 to 332: score 57.4, E = 1.8e-12
                   *->plPpgWeerkdpdsGrpYYyNheTketqWekPre<-*
                      plPpgWe+r d+  Gr+YY++h+ k+t+W++P++   
   mKIAA4011   300    PLPPGWEQRVDQH-GRVYYVDHVEKRTTWDRPEP    332  

WW: domain 2 of 4, from 333 to 364: score 49.0, E = 6e-10
                   *->plPpgWeerkdpdsGrpYYyNheTketqWekPre<-*
                       lPpgWe+r d+  Gr+YY++h T++t+W++P++   
   mKIAA4011   333    -LPPGWERRVDNM-GRIYYVDHFTRTTTWQRPTL    364  

WW: domain 3 of 4, from 412 to 444: score 68.0, E = 1.2e-15
                   *->plPpgWeerkdpdsGrpYYyNheTketqWekPre<-*
                      plPpgWe+r+d + Gr+Y++Nh+T+ tqWe+Pr+   
   mKIAA4011   412    PLPPGWEKRTDSN-GRVYFVNHNTRITQWEDPRS    444  

WW: domain 4 of 4, from 452 to 484: score 51.5, E = 1.1e-10
                   *->plPpgWeerkdpdsGrpYYyNheTketqWekPre<-*
                      plP+gWe+r++ d G pY+++h+ + t++ +Pr    
   mKIAA4011   452    PLPEGWEMRFTVD-GIPYFVDHNRRATTYIDPRT    484  

HECTc: domain 1 of 1, from 540 to 876: score 608.8, E = 1.9e-178
                   *->nsspddLkkrskeaLeIefvvnehgvgEeglDgGGvtrEFffllske
                       +sp+dL++r    L ++f       gEeglD+GGv rE+fflls+e
   mKIAA4011   540    SFSPQDLRRR----LWVIF------PGEEGLDYGGVAREWFFLLSHE 576  

                   lfnptdygLFryspndnaeksktiYigrlrylLfpnPsagfaneehlaav
                   ++np +y+LF+y + dn             y+L++nP++++ n++hl+  
   mKIAA4011   577 VLNP-MYCLFEYAGKDN-------------YCLQINPASYI-NPDHLK-- 609  

                   yFrfiGrvlGkAlyenrllDlrFarpFyKkLLgkpkgtdvtlhDleslDP
                   yFrfiGr++++Al++++++D  F++pFyK +L+kp    v l+Dles+DP
   mKIAA4011   610 YFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKP----VGLKDLESIDP 655  

                   elyksLvwLilvrrKleleeDlseeskslenditeveldmaLtFsivles
                   e+y+sL w                    +en+i+e++l+   +F +v+ +
   mKIAA4011   656 EFYNSLIWV-------------------KENNIEECGLE--MYF-SVDKE 683  

                   dfgevkvvELkpGGsnipVTeeNkkEYVhlvieyrlnkgvekqleAFreG
                    +ge k ++Lkp+G ni VTeeNk+EY++ v+e+rl +gve+q+ AF eG
   mKIAA4011   684 ILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEG 733  

                   FseVipeelLrylFdeeELeLLicGleeeidvddLksnTeyrggYtensq
                   F+e++p+  L+ +Fd++ELe L+cG++ eid++d++ +++yr +Yt++s+
   mKIAA4011   734 FNEILPQQYLQ-YFDAKELEVLLCGMQ-EIDLNDWQRHAIYR-HYTRTSK 780  

                   tirfkkwFWevvesFtneerrkLLqFVTGssrlPASvgGFaaLspsNGpq
                   +i    wFW+ v + +ne+r +LLqFVTG++rlP  vgGFa+L +sNGpq
   mKIAA4011   781 QI---MWFWQFVKEIDNEKRMRLLQFVTGTCRLP--VGGFADLMGSNGPQ 825  

                   kFtIrkagsetlsdddrLPtAhTCfNrLkLPpYsSkeiLreKLLlAIneg
                   kF+I+k+g     ++ +LP++hTCfNrL+LPpY S+e+L+eKLL AI+e 
   mKIAA4011   826 KFCIEKVG-----KENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEE- 869  

                   RiggeGFgls<-*
                      +eGFg++   
   mKIAA4011   870 ---TEGFGQE    876  

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