hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm01139/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4011  ( 876 res)   mpm01139

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
HECT     HECT-domain (ubiquitin-transferase)            617.0   1.1e-181   1
WW       WW domain                                      221.7    1.1e-62   4
C2       C2 domain                                       61.6    1.7e-14   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
C2         1/1      32   111 ..     1    88 []    61.6  1.7e-14
WW         1/4     301   330 ..     1    30 []    58.4  1.6e-13
WW         2/4     333   362 ..     1    30 []    58.2  1.8e-13
WW         3/4     413   442 ..     1    30 []    68.1  1.8e-16
WW         4/4     453   482 ..     1    30 []    52.5  9.2e-12
HECT       1/1     571   876 .]     1   366 []   617.0 1.1e-181

Alignments of top-scoring domains:
C2: domain 1 of 1, from 32 to 111: score 61.6, E = 1.7e-14
                   *->LrVtvieAknLppkDfkngksDPYVkvslggdkkdqkkkTkvikktl
                      L +tvi+Ak   +k + +  ++PYV+v+++g    q kkT+  ++t 
   mKIAA4011    32    LQITVISAKLKENKKNWF-GPSPYVEVTVDG----QSKKTEKCNNTN 73   

                   NPvWNEtFtFevpppdlqetLeieVyDydrfgrddflGevs<-*
                   +P+W + +t+   + +  + L + V+ + ++++d +lG++    
   mKIAA4011    74 SPKWKQPLTVI--VTPTSK-LCFRVWSHQTLKSDVLLGTAG    111  

WW: domain 1 of 4, from 301 to 330: score 58.4, E = 1.6e-13
                   *->LppgWeerkdpdGrpYYyNhnTktTqWekP<-*
                      LppgWe+r d++Gr+YY++h+ k+T+W++P   
   mKIAA4011   301    LPPGWEQRVDQHGRVYYVDHVEKRTTWDRP    330  

WW: domain 2 of 4, from 333 to 362: score 58.2, E = 1.8e-13
                   *->LppgWeerkdpdGrpYYyNhnTktTqWekP<-*
                      LppgWe+r d  Gr+YY++h T+tT+W++P   
   mKIAA4011   333    LPPGWERRVDNMGRIYYVDHFTRTTTWQRP    362  

WW: domain 3 of 4, from 413 to 442: score 68.1, E = 1.8e-16
                   *->LppgWeerkdpdGrpYYyNhnTktTqWekP<-*
                      LppgWe+r+d++Gr+Y++NhnT+ TqWe+P   
   mKIAA4011   413    LPPGWEKRTDSNGRVYFVNHNTRITQWEDP    442  

WW: domain 4 of 4, from 453 to 482: score 52.5, E = 9.2e-12
                   *->LppgWeerkdpdGrpYYyNhnTktTqWekP<-*
                      Lp+gWe+r++ dG pY+++hn + T++++P   
   mKIAA4011   453    LPEGWEMRFTVDGIPYFVDHNRRATTYIDP    482  

HECT: domain 1 of 1, from 571 to 876: score 617.0, E = 1.1e-181
                   *->tLlsrelfnPdygLFeysdnseakseeddsysgyvedsytlfpnPls
                      +Lls+e++nP+y+LFey+                ++d+y+l++nP s
   mKIAA4011   571    FLLSHEVLNPMYCLFEYA----------------GKDNYCLQINPAS 601  

                   gesnpehervlkyFkflGrilGlAlydgrllDlpFsraFyKklLmagkps
                   ++ np+h   lkyF+f+Gr++++Al++g+++D  Fs++FyK++L  +kp 
   mKIAA4011   602 YI-NPDH---LKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRIL--NKP- 644  

                   igivtleDlesvDPelynSLkwllendgdKkIedsLLgsledveedLeLt
                      v l+Dles+DPe+ynSL+w++en+++              e+ Le++
   mKIAA4011   645 ---VGLKDLESIDPEFYNSLIWVKENNIE--------------ECGLEMY 677  

                   FsveeessvgfeadarffGgtktveELkPnGrnipVTneNkeeYvelyvd
                   Fsv+ e    +       G++k+++ LkPnG ni VT+eNkeeY++++++
   mKIAA4011   678 FSVDKEI---L-------GEIKSHD-LKPNGGNILVTEENKEEYIRMVAE 716  

                   yrLnkgiekQfeAFrkGFsevipsrlLslFdpeELelLicGspeeiDvdd
                   +rL +g+e+Q++AF +GF+e++p + L++Fd++ELe L+cG++ eiD++d
   mKIAA4011   717 WRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQ-EIDLND 765  

                   LkenTeYdggYtedsplktiqwFWevleeftneeraklLqFvTGssRlPv
                   ++++++Y+ +Yt++s+  +i wFW+ ++e +ne+r +lLqFvTG++RlPv
   mKIAA4011   766 WQRHAIYR-HYTRTSK--QIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPV 812  

                   gGFkaLqgGsnGpPkFtIvrkegggdddrLPtAhTCFNrLkLPpYsSkei
                   gGF++L+ GsnGp+kF+I+++   g++++LP++hTCFNrL+LPpY+S+e+
   mKIAA4011   813 GGFADLM-GSNGPQKFCIEKV---GKENWLPRSHTCFNRLDLPPYKSYEQ 858  

                   LrekLllAInEgseGFgle<-*
                   L+ekLl AI E++eGFg+e   
   mKIAA4011   859 LKEKLLFAI-EETEGFGQE    876  

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