hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj10260/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA4003  ( 677 res)   mfj10260

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N 
--------     -----------                                -----    ------- ---
MCM          MCM2/3/5 family                            701.2     5e-207   1
AAA_3        ATPase family associated with various ce     4.5    0.00068   1
AAA_5        ATPase family associated with various ce     2.7      0.014   1
Mg_chelatase Magnesium chelatase, subunit ChlI         -122.8    0.00099   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
AAA_3          1/1     319   460 ..     1   133 []     4.5  0.00068
AAA_5          1/1     319   466 ..     1   184 []     2.7    0.014
Mg_chelatase   1/1     305   472 ..     1   209 []  -122.8  0.00099
MCM            1/1     259   584 ..     1   374 []   701.2   5e-207

Alignments of top-scoring domains:
AAA_3: domain 1 of 1, from 319 to 460: score 4.5, E = 0.00068
                   *->HvLlegvPGlaKTllvkalAkaldlkfkRiQaFTpDLlPsDilGtev
                       +Ll g PG+ K +l + + +++     R Q +T+    s  +G + 
   mKIAA4003   319    NILLCGDPGTSKSQLLQYVYNLV----PRGQ-YTSG-KGSSAVGLTA 359  

                   ydekt...refefkkGPvFan...llLADEINRappKtQsALLEaMeElr
                   y +k++++r++ ++ G ++ +++++   DE    +  t s L E+Me  +
   mKIAA4003   360 YVMKDpetRQLVLQTGALVLSdngICCIDEFDKMNESTRSVLHEVMEQ-Q 408  

                   qVTv..dgethkLpepFlVlATqNPieqeG........tYpLPEAqlDRF
                   + ++ ++g   +L+    VlA  NPie++ ++++++ +  +LP   l RF
   mKIAA4003   409 TLSIakAGIICQLNARTSVLAAANPIESQWnpkkttieNIQLPHTLLSRF 458  

                   ll<-*
                    l   
   mKIAA4003   459 DL    460  

AAA_5: domain 1 of 1, from 319 to 466: score 2.7, E = 0.014
                   *->pvlLvGppGtGKtelaerLaaalsgqggrpvfyvqltrdtteedllg
                      ++lL G+pGt K++l + +  +     +r     q t +  ++ + g
   mKIAA4003   319    NILLCGDPGTSKSQLLQYVYNLV----PRG----QYTSGKGSSAV-G 356  

                   rrniapll.eGngttswvdgpLvrAaryaretegslpeghilvlDEinra
                      + ++++ + +  +++ g+Lv                 i+++DE+++ 
   mKIAA4003   357 LTAY-VMKdPETRQLVLQTGALVLSDN------------GICCIDEFDKM 393  

                   spevlnvLlslLderrlllpdggelvkvppydklaergreeldlwklgrl
                   ++++  vL+ +++  +l++   g +++ ++                    
   mKIAA4003   394 NESTRSVLHEVMEQQTLSIAKAGIICQLNAR------------------- 424  

                   ihdfrlIatsNpld.......gprglnelsaALrrRFlfvtvdpp<-*
                      ++++a++Np  ++ ++++   +   l+  L++RF +++++     
   mKIAA4003   425 ---TSVLAAANPIEsqwnpkkTTIENIQLPHTLLSRFDLIFLMLD    466  

Mg_chelatase: domain 1 of 1, from 305 to 472: score -122.8, E = 0.00099
                   *->DlaDVkGQeqAKRALEIAAAGgHNLLmiGPPGsGKtMLAkRLpgILP
                      D++      + K  +EI      N+L++G PG+ K+ L +    + P
   mKIAA4003   305    DFSH---TGRGKFRAEI------NILLCGDPGTSKSQLLQYVYNLVP 342  

                   PLseeEaLEvtaihSvaGllggdgglirrRPFRaPHHsaSaaALvGGGsg
                   +  ++    + +  S++G        ++ +  R                 
   mKIAA4003   343 RGQYT----SGKGSSAVG---LTAYVMKDPETRQ--------------L- 370  

                   iprPGEISLAHnGVLFLDElPEFsrrvLEsLRqPLEdGevtIsRaaakvt
                     + G+  L  nG+   DE+   + ++  +L + +E     I+ a     
   mKIAA4003   371 VLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQ 420  

                   yPArFqLVAAmNPCPCGylgdpdkrCrCsprqirrYlsrlSGPLLDRIDl
                     Ar    AA+NP    ++  p+k +  + +  +         LL R+Dl
   mKIAA4003   421 LNARTSVLAAANPIES-QWN-PKKTTIENIQLPHT--------LLSRFDL 460  

                   qveVprlsaeeL<-*
                      +   + e++   
   mKIAA4003   461 IFLMLDPQDEAY    472  

MCM: domain 1 of 1, from 259 to 584: score 701.2, E = 5e-207
                   *->deeeirelakdpdiyeklarSIAPsIyGhedvKkAilLqLFGGvrKn
                      +++ ++el+++pdiye+la+ +APsIy+hed+Kk+ilLqLFGG+rK 
   mKIAA4003   259    RVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKD 305  

                   lpdgtr..lRGDINVLLvGDPGKTAKSQLLKyveklaPRaVYTsGkGSSA
                   +   +r+++R +IN+LL+GDPG T+KSQLL+yv +l PR++YTsGkGSSA
   mKIAA4003   306 FSHTGRgkFRAEINILLCGDPG-TSKSQLLQYVYNLVPRGQYTSGKGSSA 354  

                   aGLTAaVvrDpetgEftLEaGALVLADgGvCCIDEFDKMdesDRvAIHEA
                   +GLTA+V++Dpet++ +L  GALVL+D+G+CCIDEFDKM+es+R+++HE+
   mKIAA4003   355 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEV 404  

                   MEQQTISIAKAGIvatLNARtSvLAAANPigGRYdpsktvaeNInlpapL
                   MEQQT+SIAKAGI++ LNARtSvLAAANPi+++++p+kt +eNI+lp++L
   mKIAA4003   405 MEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTL 454  

                   LSRFDLiFvllDkpdeekDerLAeHivslHrkgepeqedeeggllvagad
                   LSRFDLiF++lD +de +D+rLA H+vsl++ +                 
   mKIAA4003   455 LSRFDLIFLMLDPQDEAYDRRLAHHLVSLYYQS----------------- 487  

                   ksaeesletepyveDllskrektlkekeidgeidpelLrkYIaYARenvk
                      ee++e+e                      +d+  L+ YIaYA  ++ 
   mKIAA4003   488 ---EEQVEEEF---------------------LDMAVLKDYIAYAHSTIM 513  

                   PkLseeAsekLvdaYvelRkegeqEsltgsssrssipITvRQLESlIRLS
                   P+LseeAs++L++aYv++Rk g        ssr+++ +++RQLESlIRL+
   mKIAA4003   514 PRLSEEASQALIEAYVNMRKIG--------SSRGMVSAYPRQLESLIRLA 555  

                   EAhAklrLseiVteeDVeeAirLlkeSlk<-*
                   EAhAk+r+s+ V++ DVeeA rL++e+lk   
   mKIAA4003   556 EAHAKVRFSNKVEAIDVEEAKRLHREALK    584  

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