hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg15810/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA3020  ( 1884 res)   mbg15810

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N 
--------       -----------                              -----    ------- ---
DENN           DENN (AEX-3) domain                      218.8    8.2e-62   1
uDENN          uDENN domain                             157.9    1.7e-43   1
Myotub-related Myotubularin-related                     115.5      1e-30   1
dDENN          dDENN domain                             106.6    4.7e-28   1
PH             PH domain                                 63.0    6.3e-15   1
GRAM           GRAM domain                               62.5    9.3e-15   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
uDENN            1/1      18   103 ..     1   108 []   157.9  1.7e-43
DENN             1/1     145   327 ..     1   231 []   218.8  8.2e-62
dDENN            1/1     380   449 ..     1    81 []   106.6  4.7e-28
GRAM             1/1     899   985 ..     1    82 []    62.5  9.3e-15
Myotub-related   1/1    1176  1269 ..     1   123 []   115.5    1e-30
PH               1/1    1779  1882 ..     1    92 []    63.0  6.3e-15

Alignments of top-scoring domains:
uDENN: domain 1 of 1, from 18 to 103: score 157.9, E = 1.7e-43
                   *->carLfDyfVvVgldkkpsglgPDelagdneylPellrqFPSKllahy
                      +arL+DyfV+V++ ++p        +g++e+++++l++FP       
   mKIAA3020    18    MARLADYFVLVAFGPHP--------RGSGEGQGQILQRFP------- 49   

                   kedhedepfdlksipkFCfPegldsvsvrevnalrdpqfFsFvLTdeDsk
                   ++d+ed+pf +++i++FC+P+g++++++r++     p+fF+ vLTd++s+
   mKIAA3020    50 EKDWEDNPF-PQGIELFCQPSGWQLCPERNP-----PTFFVAVLTDINSE 93   

                   RtryGfCltfy<-*
                   R +y+ Cltf+   
   mKIAA3020    94 R-HYCACLTFW    103  

DENN: domain 1 of 1, from 145 to 327: score 218.8, E = 8.2e-62
                   *->rvpksiCliSrlpffeaFrkvLlelkrvldssqasslppssglksgk
                      ++pk ++l+Srl + e+Fr  L +++ +++   ++s           
   mKIAA3020   145    FAPKTLVLVSRLDHAEVFRNSLGLIYAIHVEGLNVS----------- 180  

                   srdtvwrvltgvlevLhdirElEslirnLlyeVplPapGktirvkvvvls
                                        lE++i nLl++  +P  G ++r  + +  
   mKIAA3020   181 ---------------------LENVIGNLLTC-TVPLAGGSQRTISLG-- 206  

                   sgvkHyrplelilfplpdplplpledfdlaelFeaLGvenvlqLfaaaLl
                          +++++++++p+ ++lp++  ++a+lF++LG+ nvl+Lf+aaL+
   mKIAA3020   207 -------AGDRQVIQTPLVDSLPVSRCSVALLFRQLGITNVLSLFCAALT 249  

                   ErkiLflSsklsrLsscchAlvaLLYPleWqhpyIPvLPasLlsAEdvLc
                   E+k+LflS++++rL ++c+ l+aLL+Pl+++++y+P+LPa+Ll   +vL+
   mKIAA3020   250 EHKVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLL---EVLS 296  

                   APtPFlIGVhssffelvkdlpleidvvvVDLDtn<-*
                    PtPF+IGV + f+ +  +l+   dv+v DLD +   
   mKIAA3020   297 TPTPFIIGVNAAFQAETQELL---DVIVADLDGG    327  

dDENN: domain 1 of 1, from 380 to 449: score 106.6, E = 4.7e-28
                   *->lddqvreaFLrfFNasllggYrnfLryprkapewegardevvtFqke
                       d+++r++FLr+F a+ll+gYr++L++ r++pe      +v+ F+k+
   mKIAA3020   380    QDKELRAVFLRLF-AQLLQGYRWCLHIVRIHPE------PVIRFHKA 419  

                   aFLksrprssqraFlsrlletQAVemFaeFIeeR<-*
                   aFL++r +++  +Fl+++le +   +Fa+F+ eR   
   mKIAA3020   420 AFLGQRGLVED-DFLMKVLEGM---AFAGFVSER    449  

GRAM: domain 1 of 1, from 899 to 985: score 62.5, E = 9.3e-15
                   *->ekfrkiFkeilppeEkLiadckaeVysCplqrpf............s
                      +k+  +    lp+eE++++       +++l  ++++++ +++++++ 
   mKIAA3020   899    PKLLRPRL--LPGEECVLDG-----LRVYLLPDGreegvggsgggpA 938  

                   kipvqGrlYltnnrlcFrSdklgdltkegvyklviPladiervekes<-*
                    +p+ G+++lt++r++F +++ ++l+ e+v+++ +P a++++ +++s   
   mKIAA3020   939 LLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRIS    985  

Myotub-related: domain 1 of 1, from 1176 to 1269: score 115.5, E = 1e-30
                   *->YelCpsYPakLvVPksisDdeLkkvAkFRsrgRlPVLswrHqengAv
                      Y++C+sYP++L+VP+si+D +L++v+++++++R+PV++wr  +++Av
   mKIAA3020  1176    YAICRSYPGLLIVPQSIQDNALQRVSRCYRQNRFPVVCWRSGRSKAV 1222 

                   IvRcSQPLvGfsgkRckeDEkllkailkanaiDekiqskklyIvDaRprt
                   ++R++    G+ ++++     ++ +++++n      +s  +   D+    
   mKIAA3020  1223 LLRSG----GL-HGKG-----VVGLFKAQNT-----PSPGQAQADS---- 1253 

                   nAlaNrAkGGGyEneenYpnaelvfl<-*
                            ++ E +e+Y +a++  +   
   mKIAA3020  1254 ---------SSLE-QEKYLQAVVSSM    1269 

PH: domain 1 of 1, from 1779 to 1882: score 63.0, E = 6.3e-15
                   *->vikeGwLlkkg.gkkswkkRyfvLfn..dvLlyykdkk.kkpkgsip
                        +eG L+kkg + k wk R+fvL  ++++L yy+ + + ++kg+i+
   mKIAA3020  1779    RSYEGILYKKGaFMKPWKARWFVLDKtkHQLRYYDHRMdTECKGVID 1825 

                   Lsgiqvekvpdn........krkncFeirt.dretlllqaeseeerkeWv
                   L +++ + + +++ + +++ ++k  F ++t+ r ++ ++a +  ++++Wv
   mKIAA3020  1826 LAEVEAVAPGTPtigapktvDEKAFFDVKTtRR-VYNFCAQDVPSAQQWV 1874 

                   kaiqsair<-*
                   + iqs+++   
   mKIAA3020  1875 DRIQSCLS    1882 

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