hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mph/mph00541/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA3016  ( 714 res)   mph00541

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
IG       Immunoglobulin                                 114.4    1.3e-29   3
IGc2     Immunoglobulin C-2 Type                        108.7    6.7e-28   3
LRRCT    Leucine rich repeat C-terminal domain           39.1      6e-07   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
LRRCT      1/1      52   102 ..     1    55 []    39.1    6e-07
IGc2       1/3     119   185 ..     1    56 []    12.9     0.25
IG         1/3     113   197 ..     1    58 []    23.7    0.026
IGc2       2/3     212   280 ..     1    56 []    43.4    3e-08
IG         2/3     206   291 ..     1    58 []    45.2  8.6e-09
IGc2       3/3     306   371 ..     1    56 []    52.3  6.3e-11
IG         3/3     300   382 ..     1    58 []    45.5  7.1e-09

Alignments of top-scoring domains:
LRRCT: domain 1 of 1, from 52 to 102: score 39.1, E = 6e-07
                   *->NPfnCDCeLrwLlrwleaqnnealqdpvsslrCasPeslrGqpllll
                       ++ CDC+LrwL++w+ +     +q +v ++ Ca+P  l+G  ++++
   mKIAA3016    52    SSLLCDCQLRWLPQWVAE---NNFQSFV-NASCAHPQLLKGRSIFTV 94   

                   lpsefsCp<-*
                    p++f+C+   
   mKIAA3016    95 SPDGFVCD    102  

IGc2: domain 1 of 3, from 119 to 185: score 12.9, E = 0.25
                   *->leGqsVtLtCp.asgdpvp.nItWlk.gkplp............sgs
                      + G +V++tC  as ++ p ++ W+k+++ l++ + ++  + +  g+
   mKIAA3016   119    IKGSDVSFTCSaASSSDSPmTFAWKKdNEALQdaemenyahlraQGG 165  

                   tLtiknvsleDsGlYtCvArNsvg<-*
                   +L    +++  +G+Y+Cv +N+ g   
   mKIAA3016   166 EL----MEFTSEGKYQCVISNHFG    185  

IG: domain 1 of 3, from 113 to 197: score 23.7, E = 0.026
                   *->pp.vtvkeGesvtLtC.as.......titWy................
                      p+++++  G++v++tC+a+++++++ t+ W++++   ++    +  +
   mKIAA3016   113    PEtQSAIKGSDVSFTCsAAsssdspmTFAWKkdnealqdaemenyah 159  

                   .....LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-*
                    + ++ ++ + t e     G Y+C+ +++ gs +s   ++Lt+    
   mKIAA3016   160 lraqgGELmEFTSE-----GKYQCVISnhFGSSYS-VKAKLTIN    197  

IGc2: domain 2 of 3, from 212 to 280: score 43.4, E = 3e-08
                   *->leGqsVtLtCpasgdpvpnItWlk..gkplp...........sgstL
                      + G  ++L+C a g p+p+I W k++g+  p  ++++ +  + +   
   mKIAA3016   212    RAGAMARLECAAVGHPAPQIAWQKdgGTDFPaarerrmhvmpEDDVF 258  

                   tiknvsleDsGlYtCvArNsvg<-*
                    i +v+ eD G+Y+C+A+Ns+g   
   mKIAA3016   259 FIVDVKIEDIGVYSCTAQNSAG    280  

IG: domain 2 of 3, from 206 to 291: score 45.2, E = 8.6e-09
                   *->pp.vtvkeGesvtLtC.as.....titWy..................
                      p ++t ++G  ++L+C a +++ ++i W ++++++ +  + ++ +  
   mKIAA3016   206    PMdLTIRAGAMARLECaAVghpapQIAWQkdggtdfpaarerrmhvm 252  

                   .....LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-*
                   + ++ + I +v+ eD    G+Y C+a++++gs+s+  ++tLtVl   
   mKIAA3016   253 peddvFFIvDVKIEDI---GVYSCTAQnsAGSVSA--NATLTVL    291  

IGc2: domain 3 of 3, from 306 to 371: score 52.3, E = 6.3e-11
                   *->leGqsVtLtCpasgdpvpnItWlk.gkplp.........sgstLtik
                        G++++L+C+a g+p p   W+k+++pl  ++++    +++ L i 
   mKIAA3016   306    TKGETAVLQCIAGGSPPPRLNWTKdDSPLVvterhffaaGNQLLIIV 352  

                   nvsleDsGlYtCvArNsvg<-*
                   +  ++D+G+YtC+ +N  g   
   mKIAA3016   353 DSDVSDAGKYTCEMSNTLG    371  

IG: domain 3 of 3, from 300 to 382: score 45.5, E = 7.1e-09
                   *->pp.vtvkeGesvtLtC.as.....titWy..................
                        + tv  Ge+++L+C a +++++++ W++++++   + ++    ++
   mKIAA3016   300    LLdRTVTKGETAVLQCiAGgspppRLNWTkddsplvvterhffaagn 346  

                   ..LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-*
                   + L+I +  ++D+   G YtC+ +++ g+  +  +++L+V    
   mKIAA3016   347 qlLIIvDSDVSDA---GKYTCEMSntLGTERG--NVRLSVI    382  

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