hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mph/mph02039/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA3012  ( 253 res)   mph02039

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
Ras      Ras family                                     355.7   4.9e-103   1
MMR_HSR1 GTPase of unknown function                       2.9     0.0036   1
Arf      ADP-ribosylation factor family                 -33.9    2.4e-06   1
GTP_EFTU Elongation factor Tu GTP binding domain        -80.0       0.37   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
MMR_HSR1   1/1      60   175 ..     1   140 []     2.9   0.0036
Arf        1/1      44   220 ..     1   186 []   -33.9  2.4e-06
Ras        1/1      61   222 ..     1   174 []   355.7 4.9e-103
GTP_EFTU   1/1      57   224 ..     1   299 []   -80.0     0.37

Alignments of top-scoring domains:
MMR_HSR1: domain 1 of 1, from 60 to 175: score 2.9, E = 0.0036
                   *->lrvaivGrPNVGKSTLiNaLtgk..kraiVsdyPGtTrdpnegrvel
                      ++  ++G + VGKS L+ + +  +   +++s +    +d + +++el
   mKIAA3012    60    FKLLLIGDSGVGKSCLLLRFADDtyTESYISTIG---VDFKIRTIEL 103  

                   dgrqiil..vDTPGiiegaskgegelgertleaieeaDlilfVvDasegl
                   dg+ i+l++ DT+G  +              +  + a+ i++V D+++  
   mKIAA3012   104 DGKTIKLqrWDTAGQERFRTITS--------SYYRGAHGIIVVYDVTDQ- 144  

                   tedy.tieeDleiadllydeerernleltLqelekkgkPvilvlNKiD<-
                    e ++++++ l+ +d+                 + +++  +lv NK+D  
   mKIAA3012   145 -ESFnNVKQWLQEIDR----------------YASENVNKLLVGNKCD   175  

                   *
                    
   mKIAA3012     -   -    

Arf: domain 1 of 1, from 44 to 220: score -33.9, E = 2.4e-06
                   *->gflkiflkllglwnKEmRILiLGLDnAGKTTILykLklge.vvttiP
                      g  ++ +++ + ++  +++L+ G  + GK+ +L ++ ++      i 
   mKIAA3012    44    GSCSDMSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTyTESYIS 90   

                   TiG..FNvEtveykn..vkFtvWDvGGQeslRPlWrnYfpnTdavIfVVD
                   TiG +F + t+e  ++++k++ WD  GQe+ R    +Y++   ++I V D
   mKIAA3012    91 TIGvdFKIRTIELDGktIKLQRWDTAGQERFRTITSSYYRGAHGIIVVYD 140  

                   SaDrdRieeakeELhaLLneeeLadaplLilANKQDlpgAlseaEireaL
                   + D + ++  k+ L+++  +   +++  L ++NK Dl++ +++ + ++a 
   mKIAA3012   141 VTDQESFNNVKQWLQEI-DRYASENVNKLLVGNKCDLTT-KKVVDYTTAK 188  

                   gLhelkgskgkVtlegdRpWeiqgcsAvkGeGLyEGldWLsnni<-*
                   +  +   +         +p+    +sA    ++ + +   +  i   
   mKIAA3012   189 EFADSL-G---------IPFL--ETSAKNATNVEQSFMTMAAEI    220  

Ras: domain 1 of 1, from 61 to 222: score 355.7, E = 4.9e-103
                   *->KlVlvGDgGVGKSsLliRFtdnkFpeeYipTIGvDFytktvevdgkt
                      Kl+l+GD+GVGKS+Ll+RF+d++++e+Yi+TIGvDF+++t+e+dgkt
   mKIAA3012    61    KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKT 107  

                   vkLqIWDTAGQErFralrpaYYRgAqGfLLVYDITsrdSFenvkkWleei
                   +kLq WDTAGQErFr+++++YYRgA+G+++VYD+T+++SF+nvk+Wl+ei
   mKIAA3012   108 IKLQRWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEI 157  

                   lrhadkdenvpivLVGNKcDLeddedlelekqkRqVsteeGealAkelgA
                   +r+a+  env ++LVGNKcDL           k++V++ +++++A++lg 
   mKIAA3012   158 DRYAS--ENVNKLLVGNKCDLTT---------KKVVDYTTAKEFADSLG- 195  

                   lpFmETSAKtneNVeeaFeelareilk<-*
                   +pF+ETSAK+++NVe+ F+++a ei+k   
   mKIAA3012   196 IPFLETSAKNATNVEQSFMTMAAEIKK    222  

GTP_EFTU: domain 1 of 1, from 57 to 224: score -80.0, E = 0.37
                   *->krhrNigiiGHVDHGKTTLtdrLlyytgaisertleklegeakegge
                           +  iG    GK+ L+ r   +t + s +        ++    
   mKIAA3012    57    DYLFKLLLIGDSGVGKSCLLLRFADDTYTESYI------STIGVD-- 95   

                   rkgsfklaaviDkmeeErERGITIksahvsfewkdededletkakegkkr
                             i + e+    G+TIk + +                     
   mKIAA3012    96 --------FKIRTIELD---GKTIKLQRWD-------------------- 114  

                   gnelTekrhiniIDTPGHvDFtkevirGlaqaDGAiLVVdAveG.....v
                                 T G + F   ++   + a G i+V d ++ ++ ++v
   mKIAA3012   115 --------------TAGQERFRTITSSYYRGAHGIIVVYDVTDQesfnnV 150  

                   mpGfkGQTrehlrlArqlgvppiilvVaiNKiDrvgaelklppvpeelye
                    +       e  r A +   +   lv   NK+D+++       v+   y 
   mKIAA3012   151 KQ----WLQEIDRYASENVNK--LLV--GNKCDLTTKK-----VV--DYT 185  

                   elekevrellkpIgedfgvidlilaevaeddelmeyylegeeipiipiSa
                     ++++  l                                 ip+ + Sa
   mKIAA3012   186 TAKEFADSL--------------------------------GIPFLETSA 203  

                   lggdnidelsiknkLkkddlslvPwykgvSalknkgrdrgaiptLLeald
                   + + n++                                   + ++ +  
   mKIAA3012   204 KNATNVE-----------------------------------QSFMTMAA 218  

                   dylPsPe<-*
                   + +   +   
   mKIAA3012   219 E-IKKRM    224  

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