hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mib/mib04094/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA2028  ( 1392 res)   mib04094

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
MyTH4    Domain in Myosin and Kinesin Tails             143.6    2.1e-38   1
B41      Band 4.1 homologues                            107.3    1.8e-27   1
PH       Pleckstrin homology domain.                     85.4    6.8e-21   2

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PH         1/2     597   699 ..     1    82 []    55.3  8.1e-12
PH         2/2     712   821 ..     1    82 []    31.2  0.00014
MyTH4      1/1     855  1010 ..     1   166 []   143.6  2.1e-38
B41        1/1    1017  1254 ..     1   232 []   107.3  1.8e-27

Alignments of top-scoring domains:
PH: domain 1 of 2, from 597 to 699: score 55.3, E = 8.1e-12
                   *->vikeGwLlkks.........k.swkkryfvLfngvLlyyksk.....
                       +++  L  + ++++  + + ++wk+r+fvL++g Llyyks+++  +
   mKIAA2028   597    KLLKTCLASCDngknemsvrVkTWKRRWFVLKGGELLYYKSPsdvir 643  

                   kpkgsipLsgc.svre.p...cFeivt.drtlllqAeseeereeWvealq
                   kp+g i Ls   s+ +++++ + ++ t+++t++l A+s+  +eeW++ lq
   mKIAA2028   644 KPQGHIELSAScSILRgDnkqTVQLATeKHTYYLTADSPNILEEWIKVLQ 693  

                   saiaka<-*
                   s+++ +   
   mKIAA2028   694 SVLRVQ    699  

PH: domain 2 of 2, from 712 to 821: score 31.2, E = 0.00014
                   *->vikeGwLlkksk.swkkryfvLfngvLlyyksk...kpkgsipLsgc
                      +  +G L+k + +  k+++++L ++vL+y+++ +++ p g + L ++
   mKIAA2028   712    PAVKGLLTKVKHgYSKRVWCMLVGKVLYYFRNQedkFPLGQLKLWEA 758  

                   svre.p.....................cFeivt.dr..tlllqAeseeer
                   +v+e +++ +++++ + ++    + + ++ ++ +d+++t+ll  + + e+
   mKIAA2028   759 KVEEvDrscdsdedyetrgcyllsthyTIIVHPkDQgpTYLLIGS-KHEK 807  

                   eeWvealqsaiaka<-*
                   e W+ +l  a+ ++   
   mKIAA2028   808 EAWLYHLTVAVGSN    821  

MyTH4: domain 1 of 1, from 855 to 1010: score 143.6, E = 2.1e-38
                   *->fskkPiktsLLkleddkeedskeAvkiFkaILkfMGDlPlpkssssk
                      +sk+ i  +L++l+++   ++ eA+k+Fk+++ f++  +++      
   mKIAA2028   855    HSKEGILSPLTTLPSE--ALQTEAIKLFKTCQLFIN-AAVDS----- 893  

                   lytLGeaqeFnmlepspdshlelvqfIlqkglarpeLRDEiYCQliKQlt
                                 p +d+h++l+q +lq +l +peL++Ei CQliKQ++
   mKIAA2028   894 --------------PAIDYHISLAQSALQVCLTHPELQNEICCQLIKQTR 929  

                   kR..........GWeLLylctglFpPSeSrllkyLlqFLkrradqptetp
                    R+ ++++++ +GW+LL+lc+glF+P +  +l+ L+ +L+r+ad +te +
   mKIAA2028   930 RRqlqnqpgplqGWQLLALCVGLFLPHH-PFLWLLQLHLQRNADSRTEFG 978  

                   qlmaqglakycle........GaRkqpPsrlEleAik<-*
                        ++a yc++  ++++++G R+  Psr+E+ +++   
   mKIAA2028   979 -----KYAIYCQRcvertqqnGDREARPSRMEILSTL    1010 

B41: domain 1 of 1, from 1017 to 1254: score 107.3, E = 1.8e-27
                   *->spkprvlkVylldgttlefevdssttaeelletvcrklglspresey
                      +++p+ + V++++g ++ + +d stt+ee+l+t+ +  g+   ++ +
   mKIAA2028  1017    HSRPFSIPVHFMNGLYQVVGFDASTTVEEFLNTLNQDTGMRKPAQSG 1063 

                   FgLqfedkded..shWldpaktilkqdvks............pksepltl
                   F+L+ +d+ + +  h+l+ + +i++++ k+++ ++++++++ + s + +l
   mKIAA2028  1064 FALFTDDPSGRdlEHCLQGNIKICDIISKWeqaskeqqpgkcEGSRTVRL 1113 

                   yFRvkFyppdwhgppeqlkeDptrynllylQvrddilsGrlpcpseeeal
                    ++ ++y++     + + + D   + ll +Q  d+i++G +p++ ++ al
   mKIAA2028  1114 TYKNRLYFSV----QARGETDREKT-LLLYQTNDQIINGLFPLN-KDLAL 1157 

                   lLAaLalqaefGdydpeeeek.....kkslkhvakelslkrflPkqllds
                   ++AaL+ q++ Gd+  + + + ++ ++  +         +rf+Pk++++ 
   mKIAA2028  1158 EMAALLAQVDIGDFERPFSTPagpvtNQCKANQTLKQVIERFYPKRYRE- 1206 

                   ikasflqiqltlkewrerIvelhkehaglspeeaklkYLelarrLpptYG
                        + +  +l ++++r++ +++ ++g s +++ + YL +ar++p  +G
   mKIAA2028  1207 -----GCSEEQLRQLYQRLSTKWMALRGHSAADCIRIYLTVARKWP-FFG 1250 

                   velF<-*
                   + lF   
   mKIAA2028  1251 AKLF    1254 

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