hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mtj/mtj02423/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1997  ( 1226 res)   mtj02423

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N 
--------     -----------                                -----    ------- ---
Dynein_heavy Dynein heavy chain                         413.1   2.7e-120   1
DUF164       Uncharacterized ACR, COG1579               -73.0       0.41   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
DUF164         1/1      12   216 ..     1   235 []   -73.0     0.41
Dynein_heavy   1/1     526  1224 ..     1   783 []   413.1 2.7e-120

Alignments of top-scoring domains:
DUF164: domain 1 of 1, from 12 to 216: score -73.0, E = 0.41
                   *->mknelk...sLvkiqeidkekerLeerikeipkeLkkakellealkk
                       k + + ++ L  iq +  e   Le  +k+ +    k++ ll  +  
   mKIAA1997    12    VKANVQyshVLERIQPLETEQSGLELNLKKTEDRKRKLEDLLNSVGQ 58   

                   eveeleqekeelkeevkklekeiqeieekikkaEekmdeiktqrEYkALe
                   +v el +++ +   e +kle e+ ++ e ik aE+ +++         L+
   mKIAA1997    59 KVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLISQ---------LD 99   

                   rElqkakdkevtlrkeieqleeelkkieeeieelkeeilkqEkeleeeee
                   rE    + +   +  e++ l    +  +  i  l    + + k  +ee  
   mKIAA1997   100 REHRRWNAQVAEIAEELATLPKRAQLAAAFITYLSAAPEGLRKNCLEEWT 149  

                   evelEvrkikekvlellskreelkek.tdedllsfYERiiknkknlviVP
                   +    ++   +  l  +s+ +  k+++++ d ls+        +n   V 
   mKIAA1997   150 KAAGLEKFDLRRFLCTESEQLIWKSEgLPSDDLSI--------EN-ALVI 190  

                   iennvCaGChiiLpsqfenkVrkePddivfCPyCSRILYyee<-*
                   +  +vC   + i ps  +++ +k   ++            ++   
   mKIAA1997   191 LQSRVCP--FLIDPSSQATEWLKT--HL------------KD    216  

Dynein_heavy: domain 1 of 1, from 526 to 1224: score 413.1, E = 2.7e-120
                   *->lentypnpkvdwlsdqqWdsiarLseleeFrgLdddleknapdkrWk
                       ++ +++++ +w+ +++ +++a L+   ++++L + l   +  + W+
   mKIAA1997   526    QQRIRDQLP-SWIDQERSWAVATLKI--SLPSLYQTLCLED-GAFWR 568  

                   kwydseqPgEeeklPkeWkdeqklsidslkksaFqKLlllRalRPDRlty
                   + y ++ +  e+++P             +k+s Fq +l+++alRPDRl++
   mKIAA1997   569 TYYHHSMC--EQEFPSILA---------KKVSLFQQVLVVQALRPDRLQS 607  

                   alrnFveekLpGekfvepdppldlskiyekeSspstPilFiLSPGaDPsk
                   a++ F +++L G k   p  pl+l++ y+ e+ + +Pil i SPGaDPs+
   mKIAA1997   608 AMALFACKAL-GLKELSP-LPLNLKRLYK-ETLEIEPILIIISPGADPSQ 654  

                   dvekLAkkmGFtfdnGkklhSiSLGQGQgpniAekaIetAaksGhWVlLQ
                   ++ +LA+       ++  +h +++GQGQ   +A +++++ a++G W +L+
   mKIAA1997   655 ELQELASAER---SSEC-YHQVAMGQGQAD-LAIQMLKECARNGDWLCLK 699  

                   NiHLaasWLptLEKkLesltppegtHpdFRLFLTaEpaprPeehIfPigl
                   N HL+ sWLp LEK L  l+p      +FRL+LTaE +p+     f   l
   mKIAA1997   700 NLHLVVSWLPVLEKELNTLQP----KDSFRLWLTAEVHPN-----FTPIL 740  

                   LqnSiKiTNEPPtGlKANLlraysnDPIfdqeflemckkpaefkrllFlL
                   Lq+S+KiT+E P+GlK NL+r+y +    ++e++   + +  ++  lF+L
   mKIAA1997   741 LQSSLKITYESPPGLKKNLMRTYES---WTPEQISK-RDNIHRAHALFSL 786  

                   CfFHAVVqERRkFGPlGWNksYEFNesDLriSvdvldnyLeanakGRqNi
                   ++FHA  qERR+++P+GW+k+YEF+ sDLr  + v+d+  + +       
   mKIAA1997   787 AWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYHVIDRLFDGT------- 829  

                   dpdkvPWeaLRYlfGeimYGGrItDdwDrRLLrtyLeefftpelfd...g
                     + v We++ +l+   +YGGr+++++D R+L++yL +ff+ +++d  ++
   mKIAA1997   830 --KDVQWEFVHGLLENSIYGGRVDNYFDLRVLQSYLKQFFNSSIIDvlnQ 877  

                   nadyeLapkidgdlgfavPpntdyeeYieyIeesLPsessPelfGLhpNA
                   +   + +p+     ++++P++ ++ +Y   Ie+ LP+ + P  fGL++N+
   mKIAA1997   878 RNKKSIFPY-----SISLPNSCSILDYRAVIEK-LPEDDKPSFFGLPANI 921  

                   EIgfltqeteklirtllelQpreaggeldggsgekvsrkkdssEEvvkqv
                    ++ +   + + i+ l+ l  r+      +g +    r      E+ ++ 
   mKIAA1997   922 ARSSQRMISSQVISQLRILG-RSVT----AGCK--FDR------EIWSNE 958  

                   lrdileklpkklCqklFdkeelmlkr..t.eeikdPlfvVlvQEiermNk
                   l+ +l +++ kl   + +  ++ +k++++++++ +P+  + + E  ++  
   mKIAA1997   959 LSPVLNLWK-KL---NQNSNLIHQKVspPnDRQGSPILSFIILEQFNAIR 1004 

                   LlkeirrSLkeLdlglkGeltmsndlEeliksLlngrVPa.WD.mWakks
                   L++ +++SL+ L+++++G+ + s+++++l+++Lln++ P +W + W ++ 
   mKIAA1997  1005 LVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLtWQsRWEGPE 1054 

                   yPslkpLgsWvtDLlkRirQLqeWtedsGGAklglPkvvWLsGFFnPQsF
                   +P      +++  L++R+  +q+W e++     +l  + +Ls +F P +F
   mKIAA1997  1055 DPL-----QYLRGLVARTLAIQNWVEKA-EKQVLLADTLDLSELFHPDTF 1098 

                   LTAimQsvARknkwPLDkLcLdteVtkkekeeqdskepPedGvyVhGLfL
                   L+A++Q++AR+ + + D L++   +  + +e  ++       + ++GL L
   mKIAA1997  1099 LNALRQETARATGCSVDSLKFVASWKGRLQEAKLQ-------IKISGLLL 1141 

                   EGArWDsktgllaeskpKeLfspmPViwlkavpas..dkqetkdvyecPV
                   EG  +D+ + l + ++ +  +s +   +  ++p+ +     +++ +++PV
   mKIAA1997  1142 EGCSFDG-NRLSENQHDSPSVSSVLPCYMGWTPQGsyGPYSPDECISLPV 1190 

                   YktkaRggvLSTTGHStnyvftfnLktkedtpaskWilaGVALllq<-*
                   Y  ++R +           v+ +++++    ++++Wi+ G AL+l    
   mKIAA1997  1191 YTSAERER----------VVTNIDVPCGG--NQDQWIQCGAALFLK    1224 

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