hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/meh/meh01075/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1995  ( 1005 res)   meh01075

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    259.4    2.9e-73   1
TyrKc    Tyrosine kinase, catalytic domain               21.2    1.9e-12   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
S_TKc      1/1      73   329 ..     1   231 []   259.4  2.9e-73
TyrKc      1/1      73   329 ..     1   280 []    21.2  1.9e-12

Alignments of top-scoring domains:
S_TKc: domain 1 of 1, from 73 to 329: score 259.4, E = 2.9e-73
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik.........erilr
                      Y  +++lG+GaFG+  l r ++++ lv  K+++ ++ ++++++++l+
   mKIAA1995    73    YIPIRVLGRGAFGEATLYRRTEDDSLVVWKEVDltrlsekerRDALN 119  

                   EikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgrr
                   Ei iL   +H+NI+ +y +f d++ l + +Eyc+G  G+L+d + +++  
   mKIAA1995   120 EIVILALlQHDNIIAYYNHFMDnTTLLIELEYCNG--GNLYDKILRQKD- 166  

                   glrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvKl
                      k + E+++  y+ Qi+sa+  +H+ gI+HRD+K  Ni+L++ + +Kl
   mKIAA1995   167 ---KLFEEeMVVWYLFQIVSAVSCIHKAGILHRDIKTLNIFLTKanLIKL 213  

                   aDFGlArql.......ttfvGTpeYmAPEvl...gYgkpavDiWSlGcil
                   +D GlA++l+++ +   t+vGTp+Ym+PE++++ +Y++ ++DiW++Gc++
   mKIAA1995   214 GDYGLAKKLnseysmaETLVGTPYYMSPELCqgvKYNF-KSDIWAVGCVI 262  

                   yElltGkpPFp..qldlifkkig.............SpeakdLikklLvk
                   +Ellt k  F+ +++  +  ki+ + +  + +++ +S e+++L+  +L+ 
   mKIAA1995   263 FELLTLKRTFDatNPLNLCVKIVqgiramevdssqySLELIQLVHACLDQ 312  

                   dPekRlta.eaLedeldikaHPff<-*
                   dPe+R+ a+ +L         P +   
   mKIAA1995   313 DPEQRPAAdALLD-------LPLL    329  

TyrKc: domain 1 of 1, from 73 to 329: score 21.2, E = 1.9e-12
                   *->ltlgkkLGeGaFGeVykGtlk......ieVAVKtLkeda.....kee
                         +++LG+GaFGe   +tl+++++++  V  K +     +++++++
   mKIAA1995    73    YIPIRVLGRGAFGE---ATLYrrteddSLVVWKEVDLTRlsekeRRD 116  

                   FlrEakiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdL
                    l+E+ i+  l  +H+Ni++ +   ++          l+i +Ey+ gG+L
   mKIAA1995   117 ALNEIVILALL--QHDNIIAYYNHFMDN-------TTLLIELEYCNGGNL 157  

                   .ldyLrknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvge
                    ++ Lr + + +  +  + + +QI +  + +++ ++ HRD+ + N+ +++
   mKIAA1995   158 yDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILHRDIKTLNIFLTK 207  

                   nkvvKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEsl
                    + +K +D GL+++l ++         Y++     +  +     m+PE  
   mKIAA1995   208 ANLIKLGDYGLAKKLNSE---------YSM----AETLVGTPYYMSPELC 244  

                   kdgkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGy
                   +  k+++kSD+W+ G +++E++tl  +          ++  +  ++ +G 
   mKIAA1995   245 QGVKYNFKSDIWAVGCVIFELLTLKRTFDA------TNPLNLCVKIVQGI 288  

                   RlpkPendlpiSsvtCPdelYdlMlqCWaedPedRPtFsel..verl<-*
                   R +  ++         + el +l   C + dPe+RP   +l +  +l   
   mKIAA1995   289 RAMEVDS------SQYSLELIQLVHACLDQDPEQRPAADALldLPLL    329  

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