hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/Pfam Sequence file: /cdna4/rodent/full/goal/mpf/mpf00636/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA1924 ( 1782 res) mpf00636 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- WD40 WD domain, G-beta repeat 196.7 3.7e-55 18 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- WD40 1/18 414 451 .. 1 38 [] 3.6 72 WD40 2/18 466 502 .. 1 38 [] 8.1 20 WD40 3/18 580 615 .. 1 38 [] 13.8 4 WD40 4/18 619 656 .. 1 38 [] 11.4 7.9 WD40 5/18 661 698 .. 1 38 [] 25.9 0.00097 WD40 6/18 703 740 .. 1 38 [] 10.9 9.1 WD40 7/18 745 782 .. 1 38 [] 11.3 8.2 WD40 8/18 845 883 .. 1 38 [] 8.3 19 WD40 9/18 888 925 .. 1 38 [] 7.9 22 WD40 10/18 932 967 .. 1 38 [] 17.3 0.37 WD40 11/18 1181 1218 .. 1 38 [] 7.1 27 WD40 12/18 1229 1268 .. 1 38 [] 3.4 77 WD40 13/18 1324 1359 .. 1 38 [] 10.0 12 WD40 14/18 1364 1399 .. 1 38 [] 5.6 41 WD40 15/18 1460 1497 .. 1 38 [] 36.4 6.6e-07 WD40 16/18 1502 1545 .. 1 38 [] 18.2 0.2 WD40 17/18 1550 1587 .. 1 38 [] 10.3 11 WD40 18/18 1742 1778 .. 1 38 [] 20.0 0.058 Alignments of top-scoring domains: WD40: domain 1 of 18, from 414 to 451: score 3.6, E = 72 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* cl+ ++ +++++++fs + g ll+ + D++ + mKIAA1924 414 SCLSLFrSPLHTICSLSFSGS-GALLCGVGKDRHGRTVV 451 WD40: domain 2 of 18, from 466 to 502: score 8.1, E = 20 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* +la + +++ ++ + +++as++r g++++W mKIAA1924 466 VVLAKVhTD-FDIRAFQVAFFDETRMASCGR-GSVRLWR 502 WD40: domain 3 of 18, from 580 to 615: score 13.8, E = 4 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* e + g +++++++s ++a gS+Dg +++W mKIAA1924 580 EKQNFSvGSGIAISSLSVSTA---TCAVGSEDGYLRLWP 615 WD40: domain 4 of 18, from 619 to 656: score 11.4, E = 7.9 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* + H +pV++v+fspd g +++s g++ d mKIAA1924 619 SSVLLEaEHDGPVSSVSFSPD-GLRVLSTTTSGHLGFLD 656 WD40: domain 5 of 18, from 661 to 698: score 25.9, E = 0.00097 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* e + + H +pV +++ p+ + ++a+ S D+t++iWd mKIAA1924 661 EYTVLArSHMAPVLALSTEPN-RGQMATVSLDHTVRIWD 698 WD40: domain 6 of 18, from 703 to 740: score 10.9, E = 9.1 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* ++l+ ++ +++ ++vaf+p +p +++g + g ++ ++ mKIAA1924 703 QQLYDFsSSEDTPCAVAFHPT-MPNFFCGFSSGAVRSFS 740 WD40: domain 7 of 18, from 745 to 782: score 11.3, E = 8.2 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* +l +++ H +++t++ + d g++l+s+++ g++ ++ mKIAA1924 745 GVLVEHtRHRGAITSLVITLD-GRFLFSSCSQGSLVQYS 782 WD40: domain 8 of 18, from 845 to 883: score 8.3, E = 19 *->eclavl.gHtspVtcvafspd.sgpllasgSrDgtikiWd<-* l + H ++ +++fsp +sg+ll+s S+ +++ + d mKIAA1924 845 STLNLAsNHLDWAVAICFSPGnSGHLLVSTSS-NKVVVLD 883 WD40: domain 9 of 18, from 888 to 925: score 7.9, E = 22 *->eclavl..gHtspVtcvafspdsgpllasgSrDgtikiWd<-* l++l++ + +++++a s d +l+ + D+ti +Wd mKIAA1924 888 HTLRELssVRSRACCSLALSED--AHLLLAATDRTITVWD 925 WD40: domain 10 of 18, from 932 to 967: score 17.3, E = 0.37 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* +v+ gH+ pV +vaf pd + +++s ++ i +Wd mKIAA1924 932 PSCQVYiGHSEPVHAVAFTPD-QLQVISVGD--AIFLWD 967 WD40: domain 11 of 18, from 1181 to 1218: score 7.1, E = 27 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* +++ gH+ ++ +a ++d g++las+S+ g+ mKIAA1924 1181 GTQRHWlGHSQEISTLALNQD-GQILASASCCGNTAARC 1218 WD40: domain 12 of 18, from 1229 to 1268: score 3.4, E = 77 *->eclavl.gHtspVtcvafspd.sgpllasgSrDgtikiWd<-* c + l++H +V ++afspd++ + + +D+++ +W+ mKIAA1924 1229 LCRHLLsHHDTAVQALAFSPDdEFLVTLGDYADRNLALWS 1268 WD40: domain 13 of 18, from 1324 to 1359: score 10.0, E = 12 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* e++ + g s t++++ + pll +gS+ g +++Wd mKIAA1924 1324 EPIPEElGA-SELTSLCYGAS--PLLYCGSSSGQVCVWD 1359 WD40: domain 14 of 18, from 1364 to 1399: score 5.6, E = 41 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* c ++ + + + +s + +l+sgS + +++W mKIAA1924 1364 HCFLAWeADDGEIGVLLCSGS---RLISGSNTKRLRLWA 1399 WD40: domain 15 of 18, from 1460 to 1497: score 36.4, E = 6.6e-07 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* + ++ ++gH V+ v fsp +++a++++Dg++++W+ mKIAA1924 1460 TSTRLIsGHRTKVNEVVFSPG-ESHCATCGEDGSVRVWS 1497 WD40: domain 16 of 18, from 1502 to 1545: score 18.2, E = 0.2 *->eclavl.gHtspVtcvafspd.....sgpllasgSrDgtikiWd<-* e++ ++ + ++ c+a+ p++ + +++++++ g +Dgt+++++ mKIAA1924 1502 ELVIQFqVLNQSCLCLAWTPPscelpEQQQVVAGYSDGTLRVFS 1545 WD40: domain 17 of 18, from 1550 to 1587: score 10.3, E = 11 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* + H + t++afs d g++++sg Dg + i + mKIAA1924 1550 AMELKMhPHRTALTAIAFSTD-GQTILSGDKDGLVAISH 1587 WD40: domain 18 of 18, from 1742 to 1778: score 20.0, E = 0.058 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* + l+gH ++V ++f p+ g+ll+++ + + i +W+ mKIAA1924 1742 GTAQDLeGHDDSVHLCRFTPS-GRLLFTAAH-NEILVWE 1778 //