hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mnh/mnh07319/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1905  ( 742 res)   mnh07319

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
GEL      Gelsolin homology domain                       648.9   1.6e-190   6

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
GEL        1/6      44   141 ..     1   102 []   102.2    6e-26
GEL        2/6     162   254 ..     1   102 []   115.3  6.8e-30
GEL        3/6     279   374 ..     1   102 []   121.2  1.1e-31
GEL        4/6     423   516 ..     1   102 []   111.0  1.4e-28
GEL        5/6     537   623 ..     1   102 []    92.8    4e-23
GEL        6/6     642   737 ..     1   102 []   112.9  3.7e-29

Alignments of top-scoring domains:
GEL: domain 1 of 6, from 44 to 141: score 102.2, E = 6e-26
                   *->yklflwrvkgkknvrvpeVpfsqgsLnsgDcyiLdtg.......gse
                       +l++wrv+  ++v+vp  + ++g+++ gD+y+++++++++++ ++ 
   mKIAA1905    44    AGLQVWRVEKLELVPVP--QGAYGDFYVGDAYLVLHTtkssrgfSYR 88   

                   iyvWvGkkssqdEkkkAaelAvelddelrLeGppagrprptqvrvvdeGk
                   +++W+Gk++sqdE ++Aa+++v++dd+l        +++p+q r++ +G+
   mKIAA1905    89 LHFWLGKECSQDESTAAAIFTVQMDDYL--------GGKPVQSREL-QGY 129  

                   EppeFwslFggw<-*
                   E+  F ++F+g+   
   mKIAA1905   130 ESTDFVGYFKGG    141  

GEL: domain 2 of 6, from 162 to 254: score 115.3, E = 6.8e-30
                   *->yklflwrvkgkknvrvpeVpfsqgsLnsgDcyiLdtggseiyvWvGk
                      +  +l++vkg+++vr+ eVp+s++s+n gDc+i+d g +eiy+W+G+
   mKIAA1905   162    TAKRLLHVKGRRVVRATEVPLSWESFNKGDCFIIDLG-TEIYQWCGS 207  

                   kssqdEkkkAaelAvelddelrLeGppagrprptqvrvvdeGkEppeFws
                    ++  E+ kA ++A  ++d++        r+++ q +vv+eG Ep e ++
   mKIAA1905   208 SCNKYERLKASQVAIGIRDNE--------RKGRSQLIVVEEGSEPSELMK 249  

                   lFggw<-*
                   ++g +   
   mKIAA1905   250 VLGRK    254  

GEL: domain 3 of 6, from 279 to 374: score 121.2, E = 1.1e-31
                   *->yklflwrvkgkknvrvpeVpfsqgsLnsgDcyiLdtg.gseiyvWvG
                      y ++   +++k+ ++++e pfs g+L s+ c+iLd+g +++i+vW+G
   mKIAA1905   279    YMVSDASGSMKVTLVAEENPFSMGMLLSEECFILDHGaAKQIFVWKG 325  

                   kkssqdEkkkAaelAvelddelrLeGppagrprptqvrvvdeGkEppeFw
                   k+++++E+k+A+++A+e+++++       +++  tq++v++eG E+p F+
   mKIAA1905   326 KNANPQERKTAMKTAEEFLQKM-------KYSTNTQIQVLPEGGETPIFK 368  

                   slFggw<-*
                   ++F+ w   
   mKIAA1905   369 QFFKDW    374  

GEL: domain 4 of 6, from 423 to 516: score 111.0, E = 1.4e-28
                   *->yklflwrvkgkknvrvpeVpfsqgsLnsgDcyiLdtg...gseiyvW
                      +++++wrv++++ v ++  p s+g +++gDcyi++++ ++g++iy W
   mKIAA1905   423    GGVEIWRVENSGRVQID--PSSYGEFYGGDCYIILYTyprGQIIYTW 467  

                   vGkkssqdEkkkAaelAvelddelrLeGppagrprptqvrvvdeGkEppe
                   +G ++++dE +++a l+v+ld++l        ++ ++qvrv  +GkEp++
   mKIAA1905   468 QGANATRDELTMSAFLTVQLDRSL--------GGQAVQVRVS-QGKEPAH 508  

                   FwslFggw<-*
                    +slF+ +   
   mKIAA1905   509 LLSLFKDK    516  

GEL: domain 5 of 6, from 537 to 623: score 92.8, E = 4e-23
                   *->yklflwrvkgkknvrvpeVpfsqgsLnsgDcyiLdtggseiyvWvGk
                      ++lf++r + +  +r++eV++++ sLns+D ++L+ +++  ++W+Gk
   mKIAA1905   537    TRLFQVRRNLASITRIVEVDVDANSLNSNDTFVLKLPRNNGFIWIGK 583  

                   kssqdEkkkAaelAvelddelrLeGppagrprptqvrvvdeGkEppeFws
                   ++sq+E k A ++A++l+ +                r+  eGkEp+eFw 
   mKIAA1905   584 GASQEEEKGAEYVADVLKCKA--------------SRIQ-EGKEPEEFWN 618  

                   lFggw<-*
                    +gg    
   mKIAA1905   619 SLGGR    623  

GEL: domain 6 of 6, from 642 to 737: score 112.9, E = 3.7e-29
                   *->yklflwrvkgkknvrvpeVpfsqgsLnsgDcyiLdtggseiyvWvGk
                      ++  +++ +g++ ++++ ++f+q++L  +D+++Ld++  +i++W+Gk
   mKIAA1905   642    RLYGCSNKTGRFIIEEVPGEFTQDDLAEDDVMLLDAW-EQIFIWIGK 687  

                   kssqdEkkkAaelAvelddelrLeGppagrprptqvrvvdeGkEppeFws
                   ++++ Ekk + + A+ +++++     p gr ++t++ ++++G+Epp+F++
   mKIAA1905   688 DANEVEKKESVKSAKMYLETD-----PSGRDKRTPIVIIKQGHEPPTFTG 732  

                   lFggw<-*
                   +F gw   
   mKIAA1905   733 WFLGW    737  

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