hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpg/mpg03874/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA1901  ( 1234 res)   mpg03874

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       306.6    2.9e-88   1
Pkinase_Tyr Protein tyrosine kinase                      74.1    2.9e-18   1
APH         Phosphotransferase enzyme family            -16.4       0.52   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
APH           1/1       9   196 ..     1   256 []   -16.4     0.52
Pkinase       1/1       7   261 ..     1   287 []   306.6  2.9e-88
Pkinase_Tyr   1/1       7   261 ..     1   272 []    74.1  2.9e-18

Alignments of top-scoring domains:
APH: domain 1 of 1, from 9 to 196: score -16.4, E = 0.52
                   *->elrplsgGasnrtylvttgd..gdapryvlrlappg..eaaeelerE
                      +l+ +++G  + ++lv  +++++    yv +  + ++   +e+ e  
   mKIAA1901     9    RLQKIGEGSFGKAVLVKSTEdgR---HYVIKEINISrmSDKERQESR 52   

                   aavlrhLaalgipvpvpvPrvlaggtdgeglglpfllleglpGevlsrpn
                    +v+ +   +++        ++ + +  e++g ++ ++++ +G +l    
   mKIAA1901    53 REVAVLANMKHP-------NIVQYKESFEENGSLYIVMDYCEGGDLFK-- 93   

                   alspaerpallealarlLarLHqvdppalplarrlerrlkllrqlaaala
                                         ++++    l+ +         q++++  
   mKIAA1901    94 ----------------------RINAQKGALFQED--------QILDW-- 111  

                   rlvaaelldeerglllelaerllaaleallp..ppvlvHGDlhpgNvlvd
                                        + + ++al + +++ ++H+D  + N++++
   mKIAA1901   112 ---------------------FVQICLALKHvhDRKILHRDIKSQNIFLT 140  

                   dapdggrvsGvIDfedaglGdpayDlAmllrslfgeefgpefldaylaay
                      dg+    + Df+ a++     +lA+++    ++ +    + +   + 
   mKIAA1901   141 --KDGTVQ--LGDFGIARVLNSTVELARTC-I-GTPYYLSPEICENKPYN 184  

                   grqfaapglerlrel<-*
                    +   ++ ++    l   
   mKIAA1901   185 NK---SDIWALGCVL    196  

Pkinase: domain 1 of 1, from 7 to 261: score 306.6, E = 2.9e-88
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      y++l+k+G+GsfG+  + k   +g+ +++K+i+ ++ ++k++++ rr
   mKIAA1901     7    YVRLQKIGEGSFGKAVLVKSTEDGRHYVIKEINISRMSDKERQESRR 53   

                   rsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrlldLfdylse
                     E+++l++++HpNIv+++++fe++++ly+V++ycegG    dLf ++  
   mKIAA1901    54 --EVAVLANMKHPNIVQYKESFEENGSLYIVMDYCEGG----DLFKRIN- 96   

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldengv
                     +kg+l f+ed++ +++ Qi+ +l++ H+++i+HRD+K++NI+l ++g+
   mKIAA1901    97 -AQKGAL-FQEDQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDGT 144  

                   vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD
                   v     ++DFG+A++l ++  + + t  GTp+Y++PE++  +++y  k+D
   mKIAA1901   145 V----QLGDFGIARVL-NsTVElARTCIGTPYYLSPEICE-NKPYNNKSD 188  

                   vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi
                   +W+lG++lyel+t k  F        +++ l+ ki +++++  sp+ +  
   mKIAA1901   189 IWALGCVLYELCTLKHAFEAG-----NMKNLVLKIISGSFPPVSPHYS-- 231  

                   srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                                ++++L++ +++++P +R++   il+  ++   
   mKIAA1901   232 ------------YDLRSLLSQLFKRNPRDRPSVNSILEKGFI    261  

Pkinase_Tyr: domain 1 of 1, from 7 to 261: score 74.1, E = 2.9e-18
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtL.keigasseei
                       + ++k+GeG+FG   k++l  +  +++ +  +K ++     s++e 
   mKIAA1901     7    YVRLQKIGEGSFG---KAVLV-KSTEDGRHYVIKEInIS-RMSDKE- 47   

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                    r++  rE++++ ++ +HpNiV++     +  ++    lyiV+ y+egGd
   mKIAA1901    48 -RQESRREVAVLANM-KHPNIVQYKESFEE-NGS----LYIVMDYCEGGD 90   

                   LldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLV
                   L +   ++  g  +   + l++ +Qi+ ++ + +++++ HRD+   N+ +
   mKIAA1901    91 LFKRINAQ-KGALFQEDQILDWFVQICLALKHVHDRKILHRDIKSQNIFL 139  

                   senlvVKIsDFGLaRdiynddyY.vrkkgggklPvkWmAPEslkygkFts
                   +++++V  +DFG aR +    + +v     +      ++PE   ++ ++ 
   mKIAA1901   140 TKDGTVQLGDFGIARVL----NStVELARTCIGTPYYLSPEICENKPYNN 185  

                   kSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPenCPd
                   kSD+W+ G++L+E++tl     ++      ++ ++  +G   p  ++ + 
   mKIAA1901   186 KSDIWALGCVLYELCTLK-HA-FEAGNMKNLVLKI-ISGSFPPVSPHYSY 232  

                   elYdlMlqCWaedPedRPtFsel..verL<-*
                   +l +l  q  +++P dRP+   + +  ++   
   mKIAA1901   233 DLRSLLSQLFKRNPRDRPSVNSIleKGFI    261  

//