hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mph/mph01643/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1869  ( 774 res)   mph01643

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
Sema       Sema domain                                  224.3    1.8e-63   1
PSI        Plexin repeat                                  9.3        0.1   1
Extensin_2 Extensin-like region                        -103.6      0.018   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
Sema         1/1       1   335 [.     1   490 []   224.3  1.8e-63
PSI          1/1     362   425 ..     1    63 []     9.3      0.1
Extensin_2   1/1     446   767 ..     1   385 []  -103.6    0.018

Alignments of top-scoring domains:
Sema: domain 1 of 1, from 1 to 335: score 224.3, E = 1.8e-63
                   *->frtllldedrgrLyVGArNhvyvLnledlserlqqkigWpsspgeek
                                                                     
   mKIAA1869     1    -----------------------------------------Q----- 1    

                   ceeCkmkgkspgcVeteCqNfirVLqpyndthLyvCGTnaFqPvCtlinl
                             +                                       
   mKIAA1869     2 ----------Q--------------------------------------- 2    

                   gdrseaviiaetdcLFsldvekeesGkgrCPydPlhnstsvlvqgrtgeL
                                      +++e sG++rCP+d++++++++++    g L
   mKIAA1869     3 -------------------EGEELSGQARCPFDATQSTVAIFA-E--GSL 30   

                   YsGtviDssvaasFsGrdpaIrRslgshdplrTeqhdskwlnePnFVdsy
                   Ys+t++D      F  +d++++Rslg ++plr  ++dskwl eP+FV + 
   mKIAA1869    31 YSATAAD------FQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVYAL 74   

                   pipyvhsfdDdkVYFFFrEtaveyspnsgkaiysRVaRvCknDvGG.rry
                     +       ++VYFFFrE +ve++   g++ +sRVaRvCk D+GG++r 
   mKIAA1869    75 EHG-------EHVYFFFREVSVEDA-RLGRVQFSRVARVCKRDMGGsPRA 116  

                   lelnkWTTFLKARLnCSvpGeegipkfyFNeLQavfllptganlAreLgI
                   l    WT+FLK RLnCSvpG  +   fyF++LQ+                
   mKIAA1869   117 LD-RHWTSFLKLRLNCSVPG--DST-FYFDVLQSLTGPVNLHG------- 155  

                   serdpviYGVFttssnsiagpgdnSAVCaFsmsdIrqvFenGpfkhqsnE
                     r   ++GVFtt+ nsi+g    SAVCaF + dI++ F +G+fk+q + 
   mKIAA1869   156 --RS-ALFGVFTTQTNSIPG----SAVCAFYLDDIERGF-EGKFKEQRS- 196  

                   gpnskwlpyrglkvPyPRPGqCpndssgpnytStkdlPDdtlnfikshpL
                     + +w+p+   kvP+PRPG+C++    ++++S+ dlPDd+l fik hpL
   mKIAA1869   197 -LDGAWTPVSEDKVPSPRPGSCAGVGAAASFSSSQDLPDDVLLFIKAHPL 245  

                   mdevvpPlhnrPlfvgtsvnyrlTqIaVdkrVragdGqlYtVlFlGTddG
                   +d +vpP + +Pl++ ts   +lTq+aVd   +ag  ++ tVlFlG +dG
   mKIAA1869   246 LDPAVPPATHQPLLTLTSR-ALLTQVAVD--GMAGPHRNTTVLFLGSNDG 292  

                   tvlKkvvvlsrsss.syeevvleelqvfkdpriePvqnleisskq<-*
                   tvlK +    +s ++ +   vlee++ +++ r+++ ++ ++++     
   mKIAA1869   293 TVLKVLPPGGQSLGsEPI--VLEEIDAYSHARCSGKRSPRAARRI    335  

PSI: domain 1 of 1, from 362 to 425: score 9.3, E = 0.1
                   *->nCsqytsC.ssCLaardpfyCgWCssegrC.................
                      +C++++ C+ sCLa+ dp yCgW  s + C + +++++++ + ++++
   mKIAA1869   362    RCARHGACqRSCLASLDP-YCGWHRS-RGCmsirgpggtdvdltgnq 406  

                   ..trgsaytsfyGeCpraependqwldwswssskCp<-*
                   ++t ++       +C+ ++          + s+  p   
   mKIAA1869   407 esTEHG-------DCQDGA----------TGSQSGP    425  

Extensin_2: domain 1 of 1, from 446 to 767: score -103.6, E = 0.018
                   *->lltlvvalvslslpseasakYsYsSPPPpekpY....vYkSPPpPsp
                       + l++a v+  ++  as      S    +   ++++  + P +P p
   mKIAA1869   446    PIPLLLACVAAAFALGASVSGLLVSCACRRANRrrskDIETPGLPRP 492  

                   kyvykSPPPpkkpYvYsSPPPPsyvykSPPPPkpyvYkSPPpPkyvYkSP
                       +S      + +   P PP       PPP                  
   mKIAA1869   493 -LSLRS----LARLHGGGPEPP-------PPP------------KDGDAA 518  

                   PpPv.ykYkSPPPPthsppPpyvykSPPPPpkkyvykSpPpptPvYkYkS
                    +P  y    PPP            SPP           P p        
   mKIAA1869   519 QTPQlYTTFLPPPDG---------GSPPELA------CLPTPE-----TT 548  

                   PPPPpyvYkspPpPvkkripyvYkSPPPPpPYvYkSpPppvkkyiykspp
                   P  P+   + +  P +        S  P  P      P+       + + 
   mKIAA1869   549 PELPVKHLRASGGPWEWNQNGNNASEGPGRP------PRGC-----SGAG 587  

                   ppephkYvYkSPPPPpP..YvyesvpeqkikYvYkSPPPPkksYkspspp
                    p p+    + PPP  P++ v    +e+  +Y    P PP+k        
   mKIAA1869   588 GPAPR-VLVRPPPPGCPgqAVEVTTLEELLRYL-HGPQPPRK-------- 627  

                   kyVYkSpPpPvipykYkSPPPPkkkyspaP.rkpyvYkSPPP....Ptyv
                        S P    p+  +   PP     + P+   +v +SP P+++ P+  
   mKIAA1869   628 ----GSEPLASAPFTSR---PP----ASEPgASLFVDSSPMPrdgvPPLR 666  

                   YkSpPpPykpptppkiyksPPPPtP.........vyvYkspPpippikss
                      pP  +++ + + +  s P P  + +++++ + +  ++pP    +   
   mKIAA1869   667 LDVPPEGKRAAPSGRPALSAPAPRLgvggsrrlpFPTHRAPPG--LLTRV 714  

                   sppPvyvYkSpPppvysPPPPyvYssPPPPvyvynsaPvykksPPkhhYi
                   +   +  Y   P          +Y   P      +   v +ksP  +   
   mKIAA1869   715 PSGGPARYSGGPGRH------LLYLGRPEGHRGRSLKRVDVKSPLSPKPP 758  

                   YsSPPPphh<-*
                    +SPP p     
   mKIAA1869   759 LASPPQPAP    767  

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