hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mid/mid04050/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1860  ( 634 res)   mid04050

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    204.1    1.3e-56   1
UBA      Ubiquitin associated domain                     40.3    2.6e-07   1
TyrKc    Tyrosine kinase, catalytic domain              -55.9    1.1e-07   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TyrKc      1/1       1   191 [.     1   280 []   -55.9  1.1e-07
S_TKc      1/1       1   192 [.     1   231 []   204.1  1.3e-56
UBA        1/1     213   250 ..     1    38 []    40.3  2.6e-07

Alignments of top-scoring domains:
TyrKc: domain 1 of 1, from 1 to 191: score -55.9, E = 1.1e-07
                   *->ltlgkkLGeGaFGeVykGtlkieVAVKtLkedakeeFlrEakiMkkl
                                                                     
   mKIAA1860     -    ----------------------------------------------- -    

                   GgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldyLrknrpkl
                          VkL+ v+ +e       + l++vmEy++ G   dyL ++++  
   mKIAA1860     1 -------VKLFEVIETE-------KTLYLVMEYASAGEVFDYLVSHGR-M 35   

                   slsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenkvvKIsDFGLs
                   + ++      QI +   Y ++kn+vHRDL A N L++++  +KI+DFG s
   mKIAA1860    36 KEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFS 85   

                   RdlyddDkkGeskdyYrkkggkggktllPirWmAPEslkdgkFt.skSDV
                    + + +      ++  +     +g    P+   APE ++ +k+ +++ D+
   mKIAA1860    86 NEFTLG------SKLDTF----CGS--PPYA--APELFQGKKYDgPEVDI 121  

                   WSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGyRlpkPendlpi
                   WS GV L+ + + G  P  g      + +e++e++ +G   + P +    
   mKIAA1860   122 WSLGVILYTLVS-GSLPFDG-----HNLKELRERVLRG-KYRVPFY---- 160  

                   SsvtCPdelYdlMlqCWaedPedRPtFsel.verl<-*
                       ++++  ++ ++    +P++R+t +++ ++++   
   mKIAA1860   161 ----MSTDCESILRRFLVLNPAKRCTLEQImKDKW    191  

S_TKc: domain 1 of 1, from 1 to 192: score 204.1, E = 1.3e-56
                   *->YellkklGkGaFGkVylardkktgrlvAiKvikerilrEikiLkkdH
                                                                     
   mKIAA1860     -    ----------------------------------------------- -    

                   PNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgrrglrkvlsE.e
                      VkL++v+e+++ lylVmEy++   G++fd+l+++gr      + E+e
   mKIAA1860     1 ---VKLFEVIETeKTLYLVMEYASA--GEVFDYLVSHGR------MKEkE 39   

                   arfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvKlaDFGlArql.
                   ar  frQi+sa+ Y+H+++I+HRDLK eN+LLd + ++K+aDFG++ +++
   mKIAA1860    40 ARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAeaNIKIADFGFSNEFt 89   

                   .....ttfvGTpeYmAPEvl...gYgkpavDiWSlGcilyElltGkpPFp
                    +++ +tf+G+p Y APE++++++Y++p+vDiWSlG+ily l++G  PF+
   mKIAA1860    90 lgsklDTFCGSPPYAAPELFqgkKYDGPEVDIWSLGVILYTLVSGSLPFD 139  

                   ..qldlifkkig..........SpeakdLikklLvkdPekRlta.eaLed
                   +++l+++ +++++++++ + + S ++ +++++ Lv +P+kR t +++++ 
   mKIAA1860   140 ghNLKELRERVLrgkyrvpfymSTDCESILRRFLVLNPAKRCTLeQIMK- 188  

                   eldikaHPff<-*
                         + ++   
   mKIAA1860   189 ------DKWI    192  

UBA: domain 1 of 1, from 213 to 250: score 40.3, E = 2.6e-07
                   *->deekieqLleMGFsreeavdALratngNverAaeyLls<-*
                      d ++ie +++MG++ree+++AL ++++N+ +A+++Ll    
   mKIAA1860   213    DTKRIEVMVGMGYTREEIKEALTNQKYNEVTATYLLLG    250  

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