hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mid/mid04050/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1860  ( 634 res)   mid04050

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       181.7    1.2e-50   1
KA1         Kinase associated domain 1                   49.4    7.9e-11   1
UBA         UBA/TS-N domain                              33.7    4.1e-06   1
Pkinase_Tyr Protein tyrosine kinase                     -40.6    2.4e-09   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase_Tyr   1/1       1   190 [.     1   272 []   -40.6  2.4e-09
Pkinase       1/1       1   192 [.     1   287 []   181.7  1.2e-50
UBA           1/1     212   251 ..     1    45 []    33.7  4.1e-06
KA1           1/1     585   634 .]     1    50 []    49.4  7.9e-11

Alignments of top-scoring domains:
Pkinase_Tyr: domain 1 of 1, from 1 to 190: score -40.6, E = 2.4e-09
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtLkeigasseeie
                                                      VK        + e  
   mKIAA1860     1    --------------------------------VKLF---EVIETE-- 10   

                   redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL
                              k+l                        y+V+Ey+  G  
   mKIAA1860    11 -----------KTL------------------------YLVMEYASAGEV 25   

                   ldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLVs
                    d+L +h   ++ + k+     +Qi ++  Y ++kn+vHRDL A N L++
   mKIAA1860    26 FDYLVSH---GRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD 72   

                   enlvVKIsDFGLaRdiynddyYvrkkgggk.lPvkWmAPEslkygkF.ts
                    +  +KI+DFG +           +k ++        APE ++ +k++  
   mKIAA1860    73 AEANIKIADFGFSNEF----TL-GSKLDTFcGSPPYAAPELFQGKKYdGP 117  

                   kSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPenCPd
                   + D+WS GV L+ +++ G  P + g    e+ e++ +  yR p  +  + 
   mKIAA1860   118 EVDIWSLGVILYTLVS-GSLP-FDGHNLKELRERVLRGKYRVPFYM--ST 163  

                   elYdlMlqCWaedPedRPtFselverL<-*
                   +  ++ ++    +P++R t +++  +    
   mKIAA1860   164 DCESILRRFLVLNPAKRCTLEQIMKDK    190  

Pkinase: domain 1 of 1, from 1 to 192: score 181.7, E = 1.2e-50
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                                                                     
   mKIAA1860     -    ----------------------------------------------- -    

                   rsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrlldLfdylse
                                  v+l++v e+++ lylV+Ey+  G    + fdyl  
   mKIAA1860     1 ---------------VKLFEVIETEKTLYLVMEYASAG----EVFDYLV- 30   

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldengv
                     ++g++   e+ea+  ++Qi++++ Y+H+++i+HRDLK eN+Lld + +
   mKIAA1860    31 --SHGRM--KEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEAN 76   

                   vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD
                   +    KiaDFG++     + +s+l+tf+G+p+Y+APE+ +g +++g++vD
   mKIAA1860    77 I----KIADFGFSNE--FtLGSkLDTFCGSPPYAAPELFQGKKYDGPEVD 120  

                   vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi
                   +WSlGvily l++G +PF+g+     + ++l +++l+++++ +++ +   
   mKIAA1860   121 IWSLGVILYTLVSGSLPFDGH-----NLKELRERVLRGKYRVPFYMS--- 162  

                   srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                                ++ +++++ L ++P+kR+t e+i++++w+   
   mKIAA1860   163 ------------TDCESILRRFLVLNPAKRCTLEQIMKDKWI    192  

UBA: domain 1 of 1, from 212 to 251: score 33.7, E = 4.1e-06
                   *->ideelvkqLreMGGGvfsreeakkALratnnnsDverAvewLleh<-
                       d + ++ ++ MG   ++ree+k+AL +  +n  + +A+++Ll +  
   mKIAA1860   212    GDTKRIEVMVGMG---YTREEIKEALTNQKYN--EVTATYLLLGR   251  

                   *
                    
   mKIAA1860     -   -    

KA1: domain 1 of 1, from 585 to 634: score 49.4, E = 7.9e-11
                   *->ddksksvvkFEiqlyKlprldlyGvdfqRisGpqwlFkdLcsailne
                      +  + ++  FE+++++lpr++l+Gv f+R+ G++++F +L+++i+n 
   mKIAA1860   585    AGGPEPLSHFEVEVCQLPRPGLRGVLFRRVAGTALAFRTLVTRISND 631  

                   Lkv<-*
                   L++   
   mKIAA1860   632 LEL    634  

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