hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpj/mpj00538/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1845  ( 362 res)   mpj00538

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Calpain_III Calpain large subunit, domain III            55.0    1.6e-12   2

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Calpain_III   1/2      34   184 ..     1   164 []    51.8  1.5e-11
Calpain_III   2/2     203   335 ..     1   164 []     3.2  4.7e-07

Alignments of top-scoring domains:
Calpain_III: domain 1 of 2, from 34 to 184: score 51.8, E = 1.5e-11
                   *->kWelaiveGeWtRgedpsdstAGGCrNypdTFwtNPQYiitLeepDe
                        +++++ G+W++g     + AGGCrN+   F  NP + ++L ep e
   mKIAA1845    34    --HTRTLPGAWVTG-----QSAGGCRNNSC-FPCNPKFWLRLLEPSE 72   

                   ddddedsevgCsvLvaLmQKdrRke....Rrm...........Gegdmlt
                                 va++Q++rR++ +++R   + ++ + + +G+ d ++
   mKIAA1845    73 V------------CVAVLQRPRRRLvgqtRALagaspapvnlpGK-DYQA 109  

                   IGFavYevpdelnGqtnvhlsrdffltnqsrarSstFINlREVslRfrLP
                    G ++ +v+++         s  ++l + ++a+++  +  RE+ lR +L 
   mKIAA1845   110 VGLHIWKVEKRKI-------SLPRVLSAPPVAGTACHAYDREIHLRCELS 152  

                   pGeYvvVPSTFEPneegeFiLRVFSEkkante<-*
                   pG Y+ VPSTF     g F+LRVFS  k+ ++   
   mKIAA1845   153 PGYYLAVPSTFLKDVPGQFLLRVFSTGKISLS    184  

Calpain_III: domain 2 of 2, from 203 to 335: score 3.2, E = 4.7e-07
                   *->kWelaiveGeWtRgedpsdstAGGCrNypdTFwtNPQYiitLeepDe
                       We+  ++G+W+ g     +tAGG rN+ + +  NP   ++++e   
   mKIAA1845   203    EWETVQLQGCWRAG-----QTAGGSRNF-ASYPCNPCLPFSVPEGAG 243  

                   ddddedsevgCsvLvaLmQKdrRkeRrmGegdmltIGFavYevpdelnGq
                        ++       + L+Q  r +   + +  +++IGF+v++vp + + q
   mKIAA1845   244 P--RYIR-------ITLQQHCRLS---DSQ--LHPIGFHVFQVPADGENQ 279  

                   tnvhlsrdffltnqsrarSstFINlREVslRfrLPpGeYvvVPSTFEPne
                    +  l  +  l    + r ++     EVs    L  G+Y +VPST+ P  
   mKIAA1845   280 DACSLLLQEPLLSCVPHRYAQ-----EVSRLCLLSVGNYRIVPSTYLPDT 324  

                   egeFiLRVFSEkkante<-*
                   eg F       + + t+   
   mKIAA1845   325 EGTFT------VTIATR    335  

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