hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mph/mph00586/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1835  ( 646 res)   mph00586

Scores for sequence family classification (score includes all domains):
Model     Description                                   Score    E-value  N 
--------  -----------                                   -----    ------- ---
RanGAP1_C RanGAP1 C-terminal domain                     423.2   2.3e-123   1
LRR_1     Leucine Rich Repeat                            28.4    0.00017   6

Parsed for domains:
Model     Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------  ------- ----- -----    ----- -----      -----  -------
LRR_1       1/6     107   134 ..     1    25 []     0.9  1.4e+03
LRR_1       2/6     170   193 ..     1    25 []     9.9       45
LRR_1       3/6     200   227 ..     1    25 []     2.6  7.3e+02
LRR_1       4/6     294   321 ..     1    25 []     4.2  4.1e+02
LRR_1       5/6     351   372 ..     1    25 []     4.3  3.9e+02
LRR_1       6/6     379   406 ..     1    25 []     6.6  1.6e+02
RanGAP1_C   1/1     463   645 ..     1   185 []   423.2 2.3e-123

Alignments of top-scoring domains:
LRR_1: domain 1 of 6, from 107 to 134: score 0.9, E = 1.4e+03
                   *->nLeeLdLsgCNpslsgs.....lppsl.glp<-*
                       Le L+L+g N  + g +++  +++ l++ +   
   mKIAA1835   107    GLEALRLEG-N-TV-GVeaarvIAKALeKKS    134  

LRR_1: domain 2 of 6, from 170 to 193: score 9.9, E = 45
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      +L eLdLs+ N  + g+    +++ l    
   mKIAA1835   170    QLVELDLSD-N-AF-GPDGVRgFeALL    193  

LRR_1: domain 3 of 6, from 200 to 227: score 2.6, E = 7.3e+02
                   *->nLeeLdLsgCNpslsgs.....lppsl.glp<-*
                      +L+eL L++C     g ++++ l++ l  +    
   mKIAA1835   200    TLQELKLNNC--GM-GIgggkiLAAALtECH    227  

LRR_1: domain 4 of 6, from 294 to 321: score 4.2, E = 4.1e+02
                   *->nLeeLdLsgCNpslsgs.....lppsl.glp<-*
                       L++++L++ N  ++ ++++ ++++ l+ l+   
   mKIAA1835   294    LLRVINLND-N-TFT-EkggvaMAETLkTLR    321  

LRR_1: domain 5 of 6, from 351 to 372: score 4.3, E = 3.9e+02
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      +L+eL+Ls C  ++ +  ++ l +     
   mKIAA1835   351    KLKELNLSFC--EI-KRDAA-LvVAE    372  

LRR_1: domain 6 of 6, from 379 to 406: score 6.6, E = 1.6e+02
                   *->nLeeLdLsgCNpslsgs.....lppsl.glp<-*
                      +Le+LdL+g N  l g+++ + l++  +++    
   mKIAA1835   379    ELEKLDLNG-N-AL-GEegceqLQEVMdSFN    406  

RanGAP1_C: domain 1 of 1, from 463 to 645: score 423.2, E = 2.3e-123
                   *->GedaeekekkkekpvieekaPvlepplpsdvstFLafPSpEKLirLG
                      Ge+ +++ +k+++p+ +e+aPvl++p p d+stFL+fPSpEKL+rLG
   mKIAA1835   463    GEEPATPLRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPEKLLRLG 509  

                   pkrsaLIaQQvdvaDaeKVveaFLkVSSVYkdeaeVkaAVeetvDALmkk
                   pk s+LI QQ+d++D+eKVv+aFLkV SV++d+a Vk AV +++DALmkk
   mKIAA1835   510 PKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKK 559  

                   AFenssFSqSnsFitsLLVnmGLLKSEDKKvKkisvLnGpLLtLnHmVqQ
                   AF+ ssF +Sn+F+t+LL++mGLLKSED K+K+i+ L GpL+ LnH V Q
   mKIAA1835   560 AFSCSSF-NSNTFLTRLLIHMGLLKSED-KIKAIPSLHGPLMVLNHVVRQ 607  

                   eYFPkdlAsvLlAFVskpnavLEscasARhaLlitLyk<-*
                   +YFPk+lA++LlAFV+kpn++LE c++ARh Ll+tLy+   
   mKIAA1835   608 DYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYN    645  

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