hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mej/mej00370/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1783  ( 869 res)   mej00370

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
SH3_2      Variant SH3 domain                            38.2    1.9e-07   1
SH3_1      SH3 domain                                     1.9        0.1   1
Extensin_2 Extensin-like region                        -118.1      0.068   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
Extensin_2   1/1     237   600 ..     1   385 []  -118.1    0.068
SH3_1        1/1     779   835 ..     1    58 []     1.9      0.1
SH3_2        1/1     780   835 ..     1    69 []    38.2  1.9e-07

Alignments of top-scoring domains:
Extensin_2: domain 1 of 1, from 237 to 600: score -118.1, E = 0.068
                   *->lltlvvalvslslpseasakYsYsSPPPpekpYvYkSPPpPspkyvy
                        +++   +slsl  + +   + +            S PpPs   + 
   mKIAA1783   237    AQQMTTQAMSLSLEQQNQ-RHQHQAQTSGA-----TSQPPPSTTAPK 277  

                   kSPPPpkkpYvYsSPPPPsyvykSPPPPkpyvYkSPPpP.......kyvY
                      PP+ ++   +S   Ps v      P +   + P +P++ ++++ y  
   mKIAA1783   278 AKKPPA-PQEKPESNLEPSGVGLREDTP-EEAESKPQRPksfqqkrDYFQ 325  

                   kSPPpPvykYkSPPPPthsppPpyvykSPPPPpkkyvykSpPpptPvYkY
                   k    P+ +    PP      P+   +     +++    SpPp       
   mKIAA1783   326 KMGQEPIRVKTVKPPAK-VQIPQEEMEETEEEEEETAELSPPP------- 367  

                   kSPPPPp...yvYkspPpPvkk.ripyvYkSPP.....PPpPYvYkSpPp
                     PPPP+ +++   s P  vk+++ ++     P+++++PP+    +S+P 
   mKIAA1783   368 --PPPPVvkkPLKASRPKAVKEdEAEPAQEEVPtqgedPPV-HSSNSAPQ 414  

                   pvkkyiyksppppephkYvYkSPPPPpPYvyesvpeqkikYvYkSPPPPk
                          +s  pp +       PP P+P    s   ++i  +Y+S P P 
   mKIAA1783   415 HP----KPSRVPPVQS--SNSAPPRPQP----SREIRNIIRMYQSRPGPV 454  

                   ksYkspsppkyVYkSpPpPvipykYkSPPPPkkkyspaP.........rk
                              V   p +P+  +  k  P  +   +   ++ + + ++ +
   mKIAA1783   455 ----------AVPVQPTRPIKTFQKKNDPKDEALAKLGIngvhlplstSP 494  

                   pyvYkSPPPPtyvYkSpPpPyk.........pptppkiyksPPPPtPvyv
                       +SPP  ++  k  P+ +++ + +++++p +  +   sP PPt    
   mKIAA1783   495 NQGKSSPPAVVPRPKARPRLEPslsiqekqgPLRDLFGPCSPNPPT---- 540  

                   YkspPpippiksssppPvyvYkSpPppvysPPPP.yvYssPPPPvyvyns
                      +P       ++ppP+     pPp +  P  P+   ++   P+   n 
   mKIAA1783   541 ---APA------PPPPPAL----PPPLSGEPKTPsVESHALTEPMEDKNI 577  

                   aPvykksPPkhhYiYsSPPPphh<-*
                   +     +     ++Y+S P   +   
   mKIAA1783   578 STKLLVPSGSVCFSYASAPWKLF    600  

SH3_1: domain 1 of 1, from 779 to 835: score 1.9, E = 0.1
                   *->kkvvALYDYearesdELsFkkGDvitvleksdd..gWWkgrlkgtgG
                       +v+AL  Y   + + LsF +GD i +l  +  ++gW +g      G
   mKIAA1783   779    GYVIALRSYITDDNSLLSFHRGDLIRLLPVTTLepGWQFGSAG---G 822  

                   keGliPsNYVepv<-*
                   + Gl+P   V+p    
   mKIAA1783   823 RSGLFPDDVVQPA    835  

SH3_2: domain 1 of 1, from 780 to 835: score 38.2, E = 1.9e-07
                   *->ygraiedyvaAtdknenleeeeLslkkGdvvkvidvggskddd.gww
                      y++a+++y+   d++       Ls+++Gd+++++   + +  ++gw 
   mKIAA1783   780    YVIALRSYIT-DDNSL------LSFHRGDLIRLL---PVTTLEpGWQ 816  

                   lgeslggGrrrRGlvPssaveel<-*
                   +g+   gGr   Gl+P + v++    
   mKIAA1783   817 FGSA--GGRS--GLFPDDVVQPA    835  

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