hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mph/mph01858/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1753  ( 826 res)   mph01858

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
zf-CCCH    Zinc finger C-x8-C-x5-C-x3-H type (and sim    21.4      0.013   5
Extensin_2 Extensin-like region                        -140.0       0.52   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
zf-CCCH      1/5     101   128 ..     1    27 []    12.0     0.23
zf-CCCH      2/5     141   169 ..     1    27 []     4.0      2.6
zf-CCCH      3/5     232   256 ..     1    27 []     6.2      1.3
zf-CCCH      4/5     268   300 ..     1    27 []    -0.6       11
zf-CCCH      5/5     310   336 ..     1    27 []    26.4  0.00067
Extensin_2   1/1     207   598 ..     1   385 []  -140.0     0.52

Alignments of top-scoring domains:
zf-CCCH: domain 1 of 5, from 101 to 128: score 12.0, E = 0.23
                   *->yktelCrff.srtGtCkyGdrCkFaHge<-*
                         + C +++ +tG C+ Gd C+F H     
   mKIAA1753   101    SPDVYCTKYdEATGLCPEGDECPFLHRT    128  

zf-CCCH: domain 2 of 5, from 141 to 169: score 4.0, E = 2.6
                   *->yktelCrffsrt...GtC.kyGdrCkFaHge<-*
                      ykt +C   ++t+++G C+k G  C FaHg+   
   mKIAA1753   141    YKTGICI--HETdskGNCtKNGLHCAFAHGP    169  

zf-CCCH: domain 3 of 5, from 232 to 256: score 6.2, E = 1.3
                   *->yktelCrffsrtGtCkyGdrCkFaHge<-*
                      ykte+C+  +    C+ G +C++ H     
   mKIAA1753   232    YKTEPCK--KPPRLCRQGYACPYYHNS    256  

zf-CCCH: domain 4 of 5, from 268 to 300: score -0.6, E = 11
                   *->yktelCrffsrt......GtCkyGdrCkFaHge<-*
                      y+  +C++ + +++ +++G C  Gd+C++ H +   
   mKIAA1753   268    YRSSPCPNVKHGdewgdpGKCENGDACQYCHTR    300  

zf-CCCH: domain 5 of 5, from 310 to 336: score 26.4, E = 0.00067
                   *->yktelCrffsrtGtCkyGdrCkFaHge<-*
                      yk   C++ ++ G+C++G+ C FaH e   
   mKIAA1753   310    YKSTKCNDMQQAGSCPRGPFCAFAHIE    336  

Extensin_2: domain 1 of 1, from 207 to 598: score -140.0, E = 0.52
                   *->lltlvvalvslslpseasakYs...YsSPPPpekpY....vYkSPPp
                          ++  +  + p   +  Y+ ++Y+  P  ++p   ++ Y  P  
   mKIAA1753   207    ASHAMIEKILSEEPRWQETAYVlgnYKTEPCKKPPRlcrqGYACPYY 253  

                   PspkyvykSPPPpkkpYvYsSPPPPsyvykSPPPPkp.............
                      k   +SP    ++  Y S P P  v++      p++ ++++  +  +
   mKIAA1753   254 HNSKDRRRSP----RKHKYRSSPCP-NVKHGDEWGDPgkcengdacqych 298  

                   .........yvYkSPPpP..kyvYkSPPpPv..ykYkSPPPPthsppPpy
                   ++++++ ++ +YkS    + +   + P  P   +    PPP +    P  
   mKIAA1753   299 trteqqfhpEIYKSTKCNdmQQAGSCPRGPFcaFAHIEPPPLSDDVQPSS 348  

                   vykSPPPPpk.....kyvykSpPpptPvYkYkSPPPPp...yvYkspPpP
                     +SP  P +    ++    S+P  +P    +SP  P  +    + +   
   mKIAA1753   349 AVSSPTQPGPvlympSAAGDSVPV-SP----SSPHAPDlsaLLCRNSGLG 393  

                   vkkripyvYkSPPPPpPYvYkSpPppvkkyiyksppppephkYvYkSPPP
                   ++       +SPP P+     S    +   +++      p +Y+ k P  
   mKIAA1753   394 SPS---HLCSSPPGPS--RKASNLEGL---VFPGESSLAPGSYK-KAPGF 434  

                   PpP.Yv...yesvpeqkikYvYkSPPPPkksYkspsppkyVYkSpPpPvi
                      + v+ +y +  + + k +  S  P ++      p + V    P    
   mKIAA1753   435 EREdQVgaeYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDVLGILPVGS- 483  

                   pykYkSPPPPkkkyspaPrkpyvYkSPPPPtyvYkSpPpPykpptppkiy
                            P  +  ++   +     PP P    +S P   ++   p++ 
   mKIAA1753   484 ---------PLTSSISSSITSSLAATPPSPAGT-NSTPG-MNANALPFY- 521  

                   ksPPPPtPvyvYkspPpippik...sssppPvyvYkSpPppvysPPPPyv
                     P   t   v +s+     + + ++   +  +     P p+       +
   mKIAA1753   522 --PTSDTVESVIESALDDLDLNefgVAALEKTFDNSAVPHPSSVTIGGSL 569  

                   YssPPPPvyvynsaPvykksPPkhhYiYsSPPPphh<-*
                    +s  P v+      ++ +      +  +SP Pp+    
   mKIAA1753   570 LQSSAP-VN------IPGSLGSSASFHSASPSPPVS    598  

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